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1. Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b

Author

Annika Graaf, Ronja Piesche, Julia Sehl-Ewert, Christian Grund, Anne Pohlmann, Martin Beer, and Timm Harder

Subjects
pigs, HPAIV, H5N1, zoonosis, mammal, panzootic, Medicine, Infectious and parasitic diseases, RC109-216
Abstract

We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.

Published
2023
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