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Low Susceptibility of Pigs against Experimental Infection with HPAI Virus H5N1 Clade 2.3.4.4b

Authors :
Annika Graaf
Ronja Piesche
Julia Sehl-Ewert
Christian Grund
Anne Pohlmann
Martin Beer
Timm Harder
Source :
Emerging Infectious Diseases, Vol 29, Iss 7, Pp 1492-1495 (2023)
Publication Year :
2023
Publisher :
Centers for Disease Control and Prevention, 2023.

Abstract

We found that nasal and alimentary experimental exposure of pigs to highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b was associated with marginal viral replication, without inducing any clinical manifestation or pathological changes. Only 1 of 8 pigs seroconverted, pointing to high resistance of pigs to clade 2.3.4.4b infection.

Details

Language :
English
ISSN :
10806040 and 10806059
Volume :
29
Issue :
7
Database :
Directory of Open Access Journals
Journal :
Emerging Infectious Diseases
Publication Type :
Academic Journal
Accession number :
edsdoj.87d432d0e4175b9487c636edbeafc
Document Type :
article
Full Text :
https://doi.org/10.3201/eid2907.230296