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6 results on '"Ritonavir -- Dosage and administration -- Research"'

1. Lopinavir/ritonavir pharmacokinetic profile: impact of sex and other covariates following a change from twice-daily to once-daily therapy

Author

Ofotokun, Ighovwerha, Chuck, Susan K., Binongo, Jose N., Palau, Mauricio, Lennox, Jeffrey L., and Acosta, Edward P.

Subjects
Sexual intercourse -- Influence -- Research, Pharmacokinetics -- Research, Ritonavir -- Dosage and administration -- Research, Tenofovir -- Dosage and administration -- Research, Health, Influence, Research, Dosage and administration
Abstract

The aim of this study was to determine the impact of sex on the pharmacokinetics of lopinavir/ritonavir. Interaction between lopinavir/ritonavir and tenofovir was also evaluated. Steady-state plasma samples were obtained [...]

Published
2007

2. Pharmacokinetics of saquinavir with atazanavir of low-dose ritonavir administered once daily (ASPIRE I) or twice daily (ASPIRE II) in seronegative volunteers

Author

King, Jennifer R., Kakuda, Thomas N., Paul, Sunita, Tse, Man Ming, Acosta, Edward P., and Becker, Stephen L.

Subjects
Saquinavir -- Dosage and administration -- Research, Pharmacokinetics -- Research, Ritonavir -- Dosage and administration -- Research, HIV patients -- Drug therapy, Health, Drug therapy, Research, Dosage and administration
Abstract

ASPIRE I and II were prospective, 3-way sequential crossover studies in healthy volunteers to compare the safety and pharmacokinetics of saquinavir/ritonavir (SQV/RTV) with saquinavir/atazanavir (SQV/ATV) administered either once daily (QD, [...]

Published
2007

3. Ritonavir has minimal impact on the pharmacokinetic disposition of a single dose of bupropion administered to human volunteers

Author

Hesse, Leah M., Greenblatt, David J., von Moltke, Lisa L., and Court, Michael H.

Subjects
Ritonavir -- Dosage and administration -- Research, Drug interactions -- Research, Bupropion -- Dosage and administration -- Research, Health, Research, Dosage and administration
Abstract

A drug-drug interaction study was conducted to determine whether ritonavir (200 mg; 4 doses over 2 days) alters the pharmacokinetic disposition of bupropion (75 mg; once) coadministered to 7 healthy [...]

Published
2006

4. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings

Author

Chu, C.M., Cheng, V.C.C., Hung, I.F.N., Wong, M.M.L., Chan, K.H., Chan, K.S., Kao, R.Y.T., Poon, L.L.M., Wong, C.L.P., Guan, Y., Peiris, J.S.M., and Yuen, K.Y.

Subjects
Ritonavir -- Dosage and administration -- Research, Severe acute respiratory syndrome -- Drug therapy -- Research, Health
Abstract

Thorax 2004;59:252-256. doi: 10.1136/thorax.2003.012658 Background: The clinical response of patients with severe acute respiratory syndrome (SARS) to a combination of lopinavir/ritonavir and ribavirin was examined after establishing the in vitro [...]

Published
2004

5. Studies from University of Turin Further Understanding of Enzyme Inhibitors (Intracellular Antiviral Activity of Low-Dose Ritonavir in Boosted Protease Inhibitor Regimens)

Subjects
Proteases -- Research, Ritonavir -- Dosage and administration -- Research, Highly active antiretroviral therapy -- Research, Biotechnology industry, Pharmaceuticals and cosmetics industries
Abstract

By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Biotechnology. According to news reporting originating from Turin, Italy, by NewsRx correspondents, research stated, 'Protease [...]

Published
2014

6. Report Summarizes HIV/AIDS Study Findings from N. Clumeck and Co-Researchers

Subjects
Ritonavir -- Dosage and administration -- Research, Darunavir -- Dosage and administration -- Research, HIV infection -- Drug therapy -- Research, Pharmaceuticals and cosmetics industries
Abstract

New research, '96 week results from the MONET trial: a randomized comparison of darunavir/ritonavir with versus without nucleoside analogues, for patients with HIV RNA 'Treatment failure was defined as two [...]

Published
2011

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