Lopinavir/ritonavir pharmacokinetic profile: impact of sex and other covariates following a change from twice-daily to once-daily therapy

Authors :: Ofotokun, Ighovwerha
Chuck, Susan K.
Binongo, Jose N.
Palau, Mauricio
Lennox, Jeffrey L.
Acosta, Edward P.
Source :: Journal of Clinical Pharmacology. August 2007, Vol. 47 Issue 8, p970, 8 p.
Publication Year :: 2007
Abstract: The aim of this study was to determine the impact of sex on the pharmacokinetics of lopinavir/ritonavir. Interaction between lopinavir/ritonavir and tenofovir was also evaluated. Steady-state plasma samples were obtained [...]

Subjects :: Sexual intercourse -- Influence -- Research
Pharmacokinetics -- Research
Ritonavir -- Dosage and administration -- Research
Tenofovir -- Dosage and administration -- Research
Health
Influence
Research
Dosage and administration

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