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Introduction: Dermatoglyphics is one of the important diagnostic tools used in the recent days for identification of an individual. Dermatoglyphics is the study of type of patterns present on digits, palms and foot. The mesiodistal diameter of the tooth is an important factor which reveals the tooth-bone discrepancy. Deciduous second molar and permanent first molar exhibit least degree of variation. Both the dermal ridges and the enamel layer of the tooth originate from ectodermal layer and during the same period of intrauterine life. Aim: To determine and compare the dermatoglyphics with the mesiodistal width of the deciduous second molar and permanent first molar. Materials and Methods: A sample of 120 child ranaged between 6-12 years were included in the study whose digital and palmer traits were recorded using ink method and the mesiodistal widths of the deciduous second molar and permanent first molar were recorded using a vernier caliper.The data was subjected to statistical analysis using unpaired t test. results: The 'ATD' angle was found in the range of 40°-50°. The loop patterns were more common followed by whorls and arch patterns. Girls expressed a greater mesiodistal diameter of deciduous second molar than boys. No significant correlation was found in between the dermatoglyphics and tooth size. conclusion: There was no significant correlation between the finger print patterns, 'ATD' angle and the mesiodistal diameter of the deciduous second molar and the permanent first molar. [ABSTRACT FROM AUTHOR]

We describe the clinical presentation, course and pathologic findings found in three adult patients with lipid storage myopathy. Excessive lipid storage was found in Type 1 fibers of muscle. Clinical improvement on oral levo-carnitine therapy suggests the possibility of carnitine deficiency as the most likely etiology in two of the patients and one had mitochondrial myopathy confirmed on genetic analysis. [ABSTRACT FROM AUTHOR]

Hyperplastic polyps are not thought to carry a malignant potential. They are, therefore, not regularly screened by the majority of clinicians. We present two case reports of serrated adenomas that add to a small but expanding body of clinical and histological evidence that suggests a hyperplastic to neoplastic pathway. Regular colonoscopic surveillance may be indicated in at least some cases of hyperplastic polyposis [ABSTRACT FROM AUTHOR]

The design and synthesis of highly durable and active electrocatalysts are crucial for improving the hydrogen evolution reaction (HER) and oxygen reduction reaction (ORR) in proton exchange membrane fuel cells (PEMFCs). In this work, we present a novel dealloyed nanoporous PtCuNiCoMn multicomponent alloy with ligaments/pores ranging from 2-3 nm, which is in situ encapsulated in a three-dimensional, free-standing nanoporous nanotubular graphene network featuring a pore/tube diameter of ∼200 to 300 nm. This method allows precise control over the noble metal loading and alloy composition while preventing noble metal loss throughout the preparation process. The innovative bimodal nanoporous graphene/alloy structure, coupled with an open 3D spongy morphology, and optimized surface Pt electronic structure through multicomponent interaction, significantly enhances the activity for the HER/ORR, outperforming commercial Pt/C. Moreover, this design addresses the issues of Pt nanoparticle aggregation and detachment from carbon supports that typically exist in Pt/C-type catalysts, thereby substantially improving the catalytic durability, even under intense gas bubbling conditions.

High-entropy oxides (HEOs) have been showing great promise in a wide range of applications. There remains a lack of clarity regarding the influence of nanostructure and composition on their Li storage performance. Herein, a dealloying technique to synthesize hierarchical nanoporous HEOs with tunable compositions is employed. Building upon the extensively studied quinary AlFeNiCrMnO x , an additional element (Co, V, Ti, or Cu) is introduced to create senary HEOs, allowing for investigation of the impact of the added component on Li storage performance. With higher specific surface areas and oxygen vacancy concentrations, all their HEOs exhibit high Li storage performances. Remarkably, the senary HEO with the addition of V (AlNiFeCrMnVO x ) achieves an impressive capacity of 730.2 mAh g -1 at 2.0 A g -1 , which surpasses all reported performance of HEOs. This result demonstrates the synergistic interaction of the six elements in one HEO nanostructure. Additionally, the battery cycling-induced reconstruction and cation diffusion in the HEOs is uncovered, which results in an initial capacity decrease followed by a subsequent continuous capacity increase and enhanced Li ion diffusion. The results highlight the crucial roles played by both nanoporous structure design and composition optimization in enhancing Li storage of HEOs., (© 2023 Wiley‐VCH GmbH.)

Developing electrocatalysts with excellent activity and stability for water splitting in acidic media remains a formidable challenge due to the sluggish kinetics and severe dissolution. As a solution, a multi-component doped RuO 2 prepared through a process of dealloying-annealing is presented. The resulting multi-doped RuO 2 possesses a nanoporous structure, ensuring a high utilization efficiency of Ru. Furthermore, the dopants can regulate the electronic structure, causing electron aggregation around unsaturated Ru sites, which mitigates Ru dissolution and significantly enhances the catalytic stability/activity. The representative catalyst (FeCoNiCrTi-RuO 2 ) shows an overpotential of 167 mV at 10 mA cm -2 for oxygen evolution reaction (OER) in 0.5 m H 2 SO 4 solution with a Tafel slope of 53.1 mV dec -1 , which is among the highest performance reported. Moreover, it remains stable for over 200 h at a current density of 10 mA cm -2 . This work presents a promising approach for improving RuO 2 -based electrocatalysts, offering a crucial advancement for electrochemical water splitting., (© 2024 Wiley‐VCH GmbH.)

Introduction: Treatment of posterior malleolar (PM) ankle fractures remains controversial. Despite increasing recommendation for small PM fragment fixation, high quality evidence demonstrating improved clinical outcomes over the unfixated PM is limited. We describe the long term clinical and radiographical outcomes in younger adult patients with PM ankle fractures managed without PM fragment fixation., Material and Methods: A retrospective cohort study was performed on PM ankle fracture patients aged 18-55 years old admitted under our orthopaedic unit between 1st of April 2009 and 31st of October 2013. Inclusion criteria were ASA 1 and 2, independent mobility pre-trauma, no pre-existing ankle pathologies, with satisfactory bimalleolar and syndesmotic stabilisation. Open fractures, talar fractures, calcaneal fractures, pilon fractures, subsequent re-injury and major complications were excluded. All PM fragments were unfixated. Clinical outcomes were evaluated using visual analogue scale (VAS) for pain, Foot and Ankle Ability Measure (FAAM) with activities of daily living (ADL) and sports subscale for function, and patient satisfaction ratings. Osteoarthritis was assessed using modified Kellgren-Lawrence scale on follow-up weightbearing ankle radiographs., Results: Sixty-one participants were included. Mean follow-up was 10.26 years. Average PM size was 16.2 ± 7.39%. All participants were evaluated for clinical outcomes. Mean score of FAAM-ADL was 95.5 ± 7.13, FAAM-Sports 86.4 ± 15.5, patient satisfaction 86.2 ± 14.4% and pain score 1.13 ± 1.65. Radiographical outcomes were evaluated in 52 participants, showing no-to-minimal osteoarthritis in 36/52 (69%), mild osteoarthritis in 14/52 (27%) and moderate osteoarthritis in 2/52 (4%). Pain and functional scores were independent of PM fragment size, post-reduction step-off, dislocation, malleoli fractured or syndesmotic injury. PM step-off more than 1 mm and traumatic dislocation/subluxation were associated with worse radiographical osteoarthritis., Conclusion: After controlling for confounders, the unfixated smaller posterior malleolus fragment at 10-year follow-up demonstrated largely satisfactory clinical outcomes with some radiographical progression of osteoarthritis., Level of Evidence: Level III - Retrospective cohort study., Competing Interests: Declaration of Competing Interest None., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

We present an annotated catalogue of the Lepidoptera family Gelechiidae of India, comprising 351 species in 80 genera, encompassing seven subfamilies. The Indian fauna represents 7.47% of global gelechiid species diversity (i.e., 4,700 species in 500 genera). Among the seven subfamilies, Dichomeridinae is the best represented (122 species in four genera), followed by Gelechiinae (76 species in 38 genera), Anacampsinae (70 species in 16 genera), Thiotrichinae (49 species in five genera), Anomologinae (26 species in nine genera), Apatetrinae (seven species in seven genera), and Physoptilinae(single species). Information on type locality, type repository, synonyms, geographical distribution, hosts, natural enemies, and references to illustrations are provided. We also reviewed the history of descriptive work on the Gelechiidae of India, and resolved ambiguities regarding the current status of some species.

Nanoporous high-entropy oxide (np-HEO) powders with tunable composition are integrated with a poly(vinylidene fluoride) network to create self-floating solar absorber films for seawater desalination. By progressively increasing the element count, we obtain an optimized 9-component AlNiCoFeCrMoVCuTi-O x . Density functional theory (DFT) calculations reveal a remarkable reduction in its bandgap, facilitating the light-induced migration of electrons to conduction bands to generate electron-hole pairs, which recombine to produce heat. Simultaneously, the intricate light reflection and refraction pathways, shaped by the nanoporous structure, coupled with the reduced thermal conductivity attributed to the suboptimal crystalline quality of the np-HEO ensure an effective conversion of captured light into thermal energy. Consequently, all these films demonstrate an impressive absorbance rate exceeding 93% across the 250-2500 nm spectral range. Under one sun, the surface temperature of the 9-component film rapidly rises to 110 °C within 90 s with a high pure water evaporation rate of 2.16 kg m -2 h -1 .

Background: Brain imaging has been utilized as a diagnostic tool in the workup of persistent pediatric dysphagia, yet the indications for imaging and the prevalence of Chiari malformation (CM) have not been established., Objective: to evaluate the prevalence of CM anomalies in children who underwent brain magnetic resonance imaging (MRI) for pharyngeal dysphagia and to review the clinical findings in the CM group compared to the non-CM group., Methods: A retrospective cohort study of children who underwent MRI as part of the workup for the diagnosis of dysphagia in a tertiary care children's hospital between 2010 and 2021., Results: 150 patients were included. The mean age at diagnosis of dysphagia was 1 ± 3.4 years, and the mean age at MRI was 3.5 ± 4.2 years. Common comorbidities in our cohort included prematurity (n = 70, 46.7 %), gastroesophageal reflux (n = 65, 43.3 %), neuromuscular/seizure disorder (n = 53,35.3 %), and underlying syndrome (n = 16, 10.7 %). Abnormal brain findings were seen in 32 (21.3 %) patients, of whom 5 (3.3 %) were diagnosed with CM-I and 4 (2.7 %) patients with tonsillar ectopia. Clinical characteristics and dysphagia severity were similar between patients with CM-I/tonsillar ectopia and patients without tonsillar herniation., Conclusions: Brain MRI should be pursued as part of the work-up for persistent dysphagia in pediatric patients given the relatively higher prevalence of CM-I. Multi-institutional studies are required to establish the criteria and timing of brain imaging in patients with dysphagia., Competing Interests: Declaration of competing interest The authors declare that they have no conflict of interest and that this study did not receive financial support. All authors have seen and approved the manuscript. Work was performed at Children's Healthcare of Atlanta in Atlanta, GA., (Copyright © 2023 Elsevier Inc. All rights reserved.)

Anchoring single metal atom to carbon supports represents an exceptionally effective strategy to maximize the efficiency of catalysts. Recently, dual-atom catalysts (DACs) emerge as an intriguing candidate for atomic catalysts, which perform better than single-atom catalysts (SACs). However, the clarification of the polynary single-atom structures and their beneficial effects remains a daunting challenge. Here, atomically dispersed triple Zn-Co-Fe sites anchored to nitrogen-doped carbon (ZnCoFe-N-C) prepared by one-step pyrolysis of a designed metal-organic framework precursor are reported. The atomically isolated trimetallic configuration in ZnCoFe-N-C is identified by annular dark-field scanning transmission electron microscopy and spectroscopic techniques. Benefiting from the synergistic effect of trimetallic single atoms, nitrogen, and carbon, ZnCoFe-N-C exhibits excellent catalytic performance in bifunctional oxygen reduction/evolution reactions in an alkaline medium, outperforming other SACs and DACs. The ZnCoFe-N-C-based Zn-air battery exhibits a high specific capacity (liquid state: 931.8 Wh kg Zn -1 ), power density (liquid state: 137.8 mW cm -2 ; all-solid-state: 107.9 mW cm -2 ), and good cycling stability. Furthermore, density-functional theory calculations rationalize the excellent performance by demonstrating that the ZnCoFe-N-C catalyst has upshifted d-band center that enhances the adsorption of the reaction intermediates., (© 2023 Wiley-VCH GmbH.)

Understanding the growth and coarsening mechanisms of metal-organic framework (MOF) nanoparticles is crucially important for the design and fabrication of MOF materials with diverse functionalities and controllable stability. Oriented attachment (OA) growth is a common manner of MOF nanocrystal coarsening and agglomeration, but the underlying molecular mechanisms have not been well understood to date. Here we report the molecular-scale characterization of the OA interfaces of zeolitic imidazolate framework (ZIF) crystals by state-of-the-art low-dose aberration-corrected transmission electron microscopy. A series of OA interfaces with different molecular structures are captured, implying that multiple kinetic steps are involved in the OA growth of ZIF crystals from non-directional physical attractions between primary nanocrystals, lattice-aligned attachment of the ligand-capped nanocrystals, to coherent interfaces with perfect lattice alignment or stacking faults. It was found that the surface-capping organic ligands not only play an essential role in crystal lattice alignment by near-field directional interactions, but also dominate the interfacial reaction kinetics by interfacial diffusion-controlled elimination of excess surface-capping ligands. These observations provide molecular-scale insights into the OA growth mechanisms of ZIF crystals, which is important for engineering MOF crystal growth pathways by designing surface-capping ligands.

Controlling the optical properties of metal plasma nanomaterials through structure manipulation has attracted great attention for solar steam generation. However, realizing broadband solar absorption for high-efficiency vapor generation is still challenging. In this work, a free-standing ultralight gold film/foam with a hierarchical porous microstructure and high porosity is obtained through controllably etching a designed cold-rolled (NiCoFeCr) 99 Au 1 high-entropy precursor alloy with a unique grain texture. During chemical dealloying, the high-entropy precursor went through anisotropic contraction, resulting in a larger surface area compared with that from the Cu 99 Au 1 precursor although the volume shrinkage is similar (over 85%), which is beneficial for the photothermal conversion. The low Au content also results in a special hierarchical lamellar microstructure with both micropores and nanopores within each lamella, which significantly broadens the optical absorption range and makes the optical absorption of the porous film reach 71.1-94.6% between 250 and 2500 nm. In addition, the free-standing nanoporous gold film has excellent hydrophilicity, with the contact angle reaching zero within 2.2 s. Thus, the 28 h dealloyed nanoporous gold film (NPG-28) exhibits a rapid evaporation rate of seawater under 1 kW m -2 light intensity, reaching 1.53 kg m -2 h -1 , and the photothermal conversion efficiency reaches 96.28%. This work demonstrates the enhanced noble metal gold using efficiency and solar thermal conversion efficiency by controlled anisotropic shrinkage and forming a hierarchical porous foam.

Oxygen vacancy control has been one of the most efficient methods to tune the physicochemical properties of conventional oxide materials. A new conceptual multi-principal oxide (MPO) is still lacking a control approach to introduce oxygen vacancies for tuning its inherent properties. Taking multi-principal rare earth-transition metal (CeGdLa-Zr/Hf) oxides as model systems, here we report temperature induced oxygen vacancy generation (OVG) phenomenon in MPOs. It is found that the OVG is strongly dependent on the composition of the MPOs showing different degrees of oxygen loss in (CeGdLaZr)O x and (CeGdLaHf)O x under identical high temperature annealing conditions. The results revealed that (CeGdLaZr)O x remained stable single phase with a marginal decrease in the band gap of about 0.08 eV, whereas (CeGdLaHf)O x contained two phases with similar crystal structure but different oxygen vacancy concentrations causing semiconductor-to-metal like transition. Due to the intrinsic high entropy, the metallic atoms sublattice in (CeGdLaHf)O x remains rather stable, regardless of the interstitial oxygen atoms ranging from almost fully occupied (61.84 at%) to almost fully empty (8.73 at%) state in the respective crystal phases. Such highly tunable oxygen vacancies in (CeGdLa-Zr/Hf) oxides show a possible path for band gap engineering in MPOs for the development of efficient photocatalysts., (© 2023. The Author(s).)

Green-solvent-processed perovskite solar cells (PSCs) have reached an efficiency of 20%, showing great promise in safe industrial production. However, the nucleation process in green-solvent-based deposition is rarely optimized, resulting in randomized crystallization and much lowered reported efficiencies. Herein, a nanostructured tin oxide nanorods (SnO 2 -NRs) substrate is utilized to prepare a high-quality formamidinium (FA)-based perovskite film processed from a green solvent of triethyl phosphate (TEP) with a low toxic antisolvent of dibutyl ether (DEE). Compared with SnO 2 nanoparticles, the oriented SnO 2 -NRs can accelerate the formation of heterogeneous nucleation sites and retard the crystal growth process of the perovskite film, resulting in a high-quality perovskite film with uniform grain growth. Furthermore, a chlorine-terminated bifunctional supramolecule (Cl-BSM) is introduced to passivate the increasing interfacial defects due to the vast contact area in SnO 2 -NRs. Correspondingly, the substrate design of SnO 2 -NRs with Cl-BSM increases the power conversion efficiency (PCE) of green-solvent-processed PSCs to 22.42% with an open-circuit voltage improvement from 1.02 to 1.12 V, which can be attributed to the uniform grain growth and reduced carrier recombination at the SnO 2 -NRs/perovskite interface. More importantly, the photo and humidity stabilities of the unencapsulated device for up to 500 and 1000 hours are also achieved with negligible interfacial delamination after aging. This work provides a new perspective on the future industrial scale production of PSCs using environment-friendly solvents with compatible substrate design.

Three new species of tribe Grapholitini (Lepidoptera: Tortricidae: Olethreutinae) from India viz., Acanthoclita bengaluruensis Reddy and Shashank, sp. nov., Grapholita constricta Reddy and Shashank sp. nov. and Thaumatotibia ramamurthyi Shashank and Reddy, sp. nov. are recorded. Descriptions and photographic illustrations of adult habitus and genitalia are provided.

Mesoporous carbon supported non-noble metals, as promising catalysts for boosting the oxygen reduction reaction (ORR) in metal-air batteries, usually face challenges of low activity and performance degradation caused by the catalyst detachment from carbon substrates. Herein, a one-stone-two-birds strategy is reported to simultaneously improve the ORR activity and anchor nanosized MnS catalysts on a mesoporous carbon framework via nitrogen (N) and sulfur (S) dopants (MnS/NS-C). Synchrotron-based X-ray absorption spectroscopy (XAS) confirms the existence of Mn-N and Mn-S bonds, which firmly anchor active MnS nanoparticles. Density functional theory (DFT) calculations reveal that the N, S codoping lowers the d-band center of Mn and optimizes ORR intermediate adsorption. An excellent ORR performance (the onset and half-wave potential of 1.07 and 0.91 V) and long-term durability are achieved for MnS/NS-C in alkaline media. The flexible Al-air battery, using MnS/NS-C as the cathode catalyst, shows a power density of 134.6 mW cm -2 in comparison to the Pt/C-based counterpart of 106.2 mW cm -2 . This study constructs a stable interaction with non-noble catalysts and carbon substrates for enhancing catalytic activity and durability in metal-air batteries.

Background and Purpose: The American College of Radiology is now offering an accreditation pathway for programs that use peer learning. Here, we share feasibility and outcome data from a pilot peer learning program in a pediatric neuroradiology section that, in its design, follows the American College of Radiology peer learning accreditation pathway criteria., Materials and Methods: We retrospectively reviewed metrics from a peer learning program with 5 participating full-time pediatric neuroradiologists during 1 year: 1) number of cases submitted, 2) percentage of radiologists meeting targets, 3) monthly attendance, 4) number of cases reviewed, 5) learning points, and 6) improvement actions. In addition, a faculty survey was conducted and is reported here., Results: Three hundred twenty-four cases were submitted (mean, 7 cases/faculty/month). The faculty never met the monthly submission target. Peer learning meeting attendance was 100%. One hundred seventy-nine cases were reviewed during the peer learning meetings. There were 22 learning points throughout the year and 30 documented improvement actions. The faculty survey yielded the highest ratings (4.8 of 5) for ease of meeting the 100% attendance requirement and for the learning value of the peer learning sessions. The lowest rating (4.2 of 5) was given for the effectiveness of improvements as a result of peer learning discussions., Conclusions: Implementing a peer learning program that follows the American College of Radiology peer learning accreditation pathway criteria is feasible. Program metric documentation can be time-consuming. Participant feedback led to meaningful program improvement, such as improving trust, expanding case submission categories, and delegating tasks to administrative staff. Effort to make peer learning operations more efficient and more effective is underway., (© 2022 by American Journal of Neuroradiology.)

Aim: The aim of this study was to compare the wear behavior of human tooth enamel opposing monolithic zirconia and layered zirconia after glazing and polishing by a two-body wear mechanism using a wear simulator., Settings and Design: This In-vitro study was done in Department of Prosthodontics, Sri Sai College of Dental Research, Vikarabad., Materials and Methods: Zirconia specimens were divided into four groups (n = 15), Group monolithic glazed zirconia (MG), Group monolithic polished zirconia (MP), Group zirconia layered with E. max ceram and glazed (LG), Group zirconia layered with E. max ceram and polished without glaze (LP). Sixty human premolar teeth were subjected to wear test against the zirconia specimens using a Pin on Disc wear tester under a constant load of 5 kg (49 N) at 30 rpm for 10,000 cycles. The loss of enamel was recorded before and after the wear test and mean loss of height of tooth enamel after 10,000 cycles of wear was measured with a profile projector. The surface characteristics of all the four group zirconia specimens were evaluated qualitatively with scanning electron microscope., Statistical Analysis Used: One way ANOVA, Tukey Post hoc., Results: One-way analysis of variance test revealed that the mean loss of enamel of four groups was statistically different with P < 0.001. A further Tukey post hoc test revealed that the MP group had lesser mean scores than group LP, MG, and LG., Conclusion: It was concluded that MP caused less wear to opposing natural teeth, and polished surfaces of both monolithic and layered zirconia showed less tooth wear compared to glazed surfaces of monolithic and layered zirconia., Competing Interests: None

Lightweight polycrystalline ceramics possess promising physical, chemical, and mechanical properties, which can be used in a variety of important structural applications. However, these ceramics with coarse-grained structures are brittle and have low fracture toughness due to their rigid covalent bonding (more often consisting of high-angle grain boundaries) that can cause catastrophic failures. Nanocrystalline ceramics with soft interface phases or disordered structures at grain boundaries have been demonstrated to enhance their mechanical properties, such as strength, toughness, and ductility, significantly. In this review, the underlying deformation mechanisms that are contributing to the enhanced mechanical properties of superhard nanocrystalline ceramics, particularly in boron carbide and silicon carbide, are elucidated using state-of-the-art transmission electron microscopy and first-principles simulations. The observations on these superhard ceramics revealed that grain boundary sliding induced amorphization can effectively accommodate local deformation, leading to an outstanding combination of mechanical properties., Competing Interests: The authors declare that they have no conflict of interest in this work.

Background: Percutaneous Endoscopic Gastrostomy (PEG) tubes are often placed for dysphagia following a stroke in order to maintain sufficient caloric intake. The 2011 ASGE guidelines recommend delaying PEG tube placement for two weeks, as half of patients with dysphagia improve within 2 wk. There are few studies comparing outcomes based on timing of PEG tube placement, and there is increasing demand for early PEG tube placement to meet requirements for timely discharge to rehab and skilled nursing facilities., Aim: To assess the safety of early (≤ 7 d post stroke) vs late (> 7 d post stroke) PEG tube placement and evaluate whether pre-procedural risk factors could predict mortality or complications., Methods: We performed a retrospective study of patients undergoing PEG tube placement for dysphagia following a stroke at two hospitals in Saint Louis, MO between January 2011 and December 2017. Patients were identified by keyword search of endoscopy reports. Mortality, peri-procedural complication rates, and post-procedural complication rates were compared in both groups. Predictors of morbidity and mortality such as protein-calorie malnutrition, presence of an independent cardiovascular risk equivalent, and presence of Systemic inflammatory response syndrome (SIRS) criteria or documented infection were evaluated by multivariate logistic regression., Results: 154 patients had a PEG tube placed for dysphagia following a stroke, 92 in the late group and 62 in the early group. There were 32 observed deaths, with 8 occurring within 30 d of the procedure. There was an increase in peri-procedural and post-procedural complications with delayed PEG placement which was not statistically significant. Hospital length of stay was significantly less in patients with early PEG tube placement (12.9 vs 22.34 d, P < 0.001). Protein calorie malnutrition, presence of SIRS criteria and/or documented infection prior to procedure or having a cardiovascular disease risk equivalent did not significantly predict mortality or complications., Conclusion: Early PEG tube placement following a stroke did not result in a higher rate of mortality or complications and significantly decreased hospital length of stay. Given similar safety outcomes in both groups, early PEG tube placement should be considered in the appropriate patient to potentially reduce length of hospital stay and incurred costs., Competing Interests: Conflict-of-interest statement: None of the authors have any conflicts of interest., (©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.)

"Inherited metabolic disorders represent a large group of disorders of which approximately 25% present in neonatal period with acute metabolic decompensation, rapid clinical deterioration, and often nonspecific imaging findings. Neonatal onset signifies the profound severity of the metabolic abnormality compared with cases with later presentation and necessitates rapid diagnosis and urgent therapeutic measures in an attempt to decrease the extent of brain injury and prevent grave neurologic sequela or death. Here, the authors discuss classification and clinical and imaging findings in a spectrum of metabolic and endocrine disorders with neonatal presentation.", (Copyright © 2022 Elsevier Inc. All rights reserved.)

Nanostructured high-entropy materials such as alloys, oxides, etc. , are attracting extensive attention because of their widely tunable surface electronic structure/catalytic activity through mixing different elements in one system. To further tune the catalytic performance and multifunctionality, the designed fabrication of multicomponent high-entropy nanocomposites such as high-entropy alloy@high-entropy oxides (HEA@HEO) should be very promising. In this work, we design a two-step alloying-dealloying strategy to synthesize ultra-small HEA nanoclusters (∼2 nm) loaded on nanoporous HEO nanowires, and the compositions of both the HEA and HEO can be adjusted separately. To demonstrate this concept, a seven-component HEA (PtPdAuAgCuIrRu) clusters@seven-component HEO (AlNiCoFeCrMoTi) 3 O 4 was prepared, which is highly active for both oxygen evolution and reduction reactions. Our comprehensive experimental results and first-principles density functional theory (DFT) calculations clearly show that better oxygen evolution reaction (OER) performance is obtained by optimizing the composition of the HEO support, and the seven-component HEA nanocluster is much more active for the ORR when compared with pure Pt due to the modified surface electronic structure. Specifically, the high-entropy composite exhibits an OER activity comparable to the best reported value, and the ORR activity exceeded the performance of commercial Pt/C in alkaline solutions with a record-low bifunctional Δ E of 0.61 V in 0.1 M KOH solution. This work shows an important route to prepare complex HEA@HEO nanocomposites with tuned catalytic performance for multifunctional catalysis and energy conversion., Competing Interests: The authors declare no conflict of interest., (This journal is © The Royal Society of Chemistry.)

Aim: The aim of the study was to compare the efficiency of three denture cleansers (Valclean, Polident and Clinsodent) in removal of turmeric stains from flexible denture base resins., Settings and Design: In vitro - comparative study., Materials and Methods: A total of 45 specimens of flexible denture base resins were fabricated and subjected to baseline colour measurements using spectrophotometer. Specimens were stained with turmeric and colour measurements of stained specimens were made. All the stained specimens were divided into three groups (n = 15) for removal of stains with three denture cleansers: Valclean, Polident, Clinsodent and colour measurements of cleansed specimens were made. The colour measurements (ΔE) values obtained were collected and statistical analysis was done., Statistical Analysis Used: One-way ANOVA (Analysis of Variance), Tukey's post hoc test., Results: One way ANOVA test revealed that the mean colour difference of three groups were statistically different with P value < 0.001. A further Tukey post hoc test revealed that the Valclean group had lesser mean scores than Polident and Clinsodent group., Conclusion: It was concluded that Valclean showed statistically significant greater stain removal efficiency than Polident followed by Clinsodent., Competing Interests: None

Context: Preterm birth is defined as births before 37 weeks of gestational age. Preterm birth is a major challenge in obstetric health care and leading cause of perinatal mortality and long-term morbidity. Complications arising from preterm births are the leading cause of deaths among children less than 5 years of age. Seventy-five percent of them could be saved with current, cost-effective interventions. The rate of preterm births worldwide is 5-18% with the developing countries accounting for the maximum deaths., Aims: This study was undertaken to evaluate the prevalence of preterm births and risk factors associated with it among women delivered at a rural tertiary teaching hospital in Telangana and further assess its impact on perinatal outcome., Settings and Design: This was a retrospective case control study conducted at Mediciti Institute of Medical Sciences from January 2019 to December 2019., Methods and Material: Of the 1243 deliveries during the study period, 135 births that occurred at <37 weeks were taken as cases and 248 term neonates were taken as control group. Data were collected retrospectively through review of prenatal and hospital delivery records., Statistical Analysis Used: Data were collected and tabulated as shown in the results. Statistical analysis was done using Microsoft Excel. Frequency and percentage of each parameter were calculated and analyzed. The risk estimates were analyzed between the cases and controls by calculating the odds ratio, 95% confidence interval, and P value. P Value of <0.05 was considered significant., Results: The prevalence rate of preterm birth was 10.86%. History of previous preterm birth (OR = 4.88, C.I: 1.50-15.87, P = 0.0084), previous LSCS (OR = 2.16, C.I: 1.36-3.44, P = 0.001), inter-pregnancy interval <12 months (OR = 2.78, C.I: 1.13-6.84, P = 0.026), hypertension (OR = 3.10, C.I: 1.78-5.42, P = 0.0001), PROM (OR =0.73, C.I: 2.36-9.49, P < 0.0001), Oligohydramnios (OR = 3.58, C.I: 1.29-9.9, P = 0.01), and multiple pregnancy (OR = 24.09, C.I: 3.09-187.46, P = 0.0024) were found to be significant risk factors for preterm birth. Though the NICU admission rate was high (52%), neonatal outcome was found to be satisfactory., Conclusions: Some of the risk factors that contributed to preterm birth were modifiable. Preventive strategies addressing the risk factors such as hypertension, oligohydramnios, and also improving health care quality to pregnant women will reduce the prevalence of preterm births and outcomes., Competing Interests: There are no conflicts of interest., (Copyright: © 2022 Journal of Family Medicine and Primary Care.)

Heteronuclear double-atom catalysts, unlike single atom catalysts, may change the charge density of active metal sites by introducing another metal single atom, thereby modifying the adsorption energies of reaction intermediates and increasing the catalytic activities. First, density functional theory calculations are used to figure out the best combination by modeling two transition-metal atoms from Fe, Co, and Ni onto N-doped graphene. Generally, Fe and Co sites are highly active for the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER), respectively. The combination of Co and Fe to form CoFe-N-C not only further improves the Fe's ORR and Co's OER activities but also greatly enhances the Co site's ORR and Fe site's OER activities. Then, we synthesize the CoFe-N-C by a two-step pyrolysis process and find that the CoFe-N-C exhibits exceptional ORR and OER electrocatalytic activities in alkaline media, significantly superior to Fe-N-C and Co-N-C and even commercial catalysts.

Zn-ion batteries (ZIBs) using aqueous electrolyte, recently, have been a hot topic owing to the high safety, low cost, and high specific energy capacity. However, the formation of dendrite and side reactions on the Zn anode during cycling inhibit the application of ZIBs. An advanced Zn anode by alloying a small amount of Li and Mn with Zn is hereby reported. It is found that Li and Mn can form cationic ions which restrain lateral diffusion of Zn ions and regulate zinc electrodeposition through the electrostatic shield mechanism. As a result, the formation of Zn dendrite is greatly inhibited. This process also mitigates the formation of Zn-based byproduct and Zn passivation. Consequently, the symmetric ZnLiMn/ZnLiMn cell presents a small overpotential of 30 mV at 1 mA cm -2 , greatly enhanced cycling durability (1000 h at a current density of 1 mA cm -2 ), and a dendrite-free morphology after cycles. Moreover, the authors find that the ZnLiMn alloy has greatly enhanced mechanical properties. The assembled ZnLiMn/MnO 2 full cell can retain 96% capacity after 400 cycles at 1 C. Thus, the alloying low-cost Li/Mn strategy is very promising for large-scale production of dendrite-free Zn electrode in rechargeable ZIBs., (© 2022 Wiley-VCH GmbH.)

Single-atom cobalt-based CoNC are promising low-cost electrocatalysts for oxygen reduction reaction (ORR). However, further increasing the single cobalt-based active sites and the ORR activity remain a major challenge. Herein, an acetate (OAc) assisted metal-organic framework (MOF) structure-engineering strategy is developed to synthesize hierarchical accordion-like MOF with higher loading amount and better spatial isolation of Co and much higher yield when compared with widely reported polyhedron MOF. After pyrolysis, the accordion-structured CoNC (CoNC (A)) is loaded with denser CoN 4 active sites (Co: 2.88 wt%), approximately twice that of Co in the CoNC reported. The presence of OAc in MOF also induces the generation of big pores (5-50 nm) for improving the accessibility of active sites and mass transfer during catalytic reactions. Consequently, the CoNC (A) catalyst shows an admirable ORR activity with a E 1/2 of 0.89 V (40 mV better than Pt/C) in alkaline electrolytes, outstanding durability, and absolute tolerance to methanol in both alkaline and acidic media. The CoNC-based Zn-air battery exhibits a high specific capacity (976 mAh g -1 Zn ), power density (158 mW cm -2 ), rate capability, and long-term stability. This work demonstrates a reliable approach to construct single atom doped carbon catalysts with denser accessible active sites through MOF structure engineering., (© 2021 Wiley-VCH GmbH.)

Intussusception more commonly occurs in pediatrics but is a rare cause of bowel obstruction and gastrointestinal bleeding in adults. It typically occurs in adults due to a malignancy, which serves as a pathologic lead point. We present a case of a 64-year-old female with nausea, vomiting, and melena who was found to have intussusception associated with a primary jejunal amelanotic melanoma. Both intussusception and primary small bowel melanomas are rare causes of obstruction and bleeding. Intussusception occurring as a result of a primary small bowel amelanotic melanoma is exceedingly rare with very few reported cases. We provide a case report and review of the literature., (© 2021. Japanese Society of Gastroenterology.)

Aim: The aim of this study was to evaluate and compare the shear bond strength between ceramic layered over titanium and ceramic layered over cobalt-chromium alloy, which are used in the fabrication of screw-retained implant prosthesis., Settings and Design: In-vitro - Comparative study., Materials and Method: A total of 40 samples (20 samples of Titanium in Group 1 and 20 samples of Cobalt-Chromium in Group 2) were fabricated. For all the samples bonding agent was applied on to the sand blasted surface and firing was done at a temperature of 980° C. A layer of opaque was applied using a brush and placed back in the furnace at a temperature of 910° C. Then ceramic was layered on to the surface with putty index as guide and firing was done in the ceramic furnace up to a temperature of 880° C followed by glazing. Shear bond strength was measured using a Universal Testing Machine., Statistical Analyses Used: One sample t-test and paired sample t-test., Results: Descriptive statistics were done to calculate mean differences between groups and samples. The mean bond strength of titanium- ceramic samples was more than those of cobalt-chromium-ceramic samples. Inferential statistics used in the study were one sample t-test for intra-group comparison and paired sample t-test for inter group comparison which showed no statistically significant difference between the two metal types (P value = 0.163)., Conclusion: The shear bond strength of ceramic veneered over titanium meets the ISO requirements of minimum shear bond strength between metal-ceramic systems and has achieved the clinically acceptable values. The use of titanium super structure over titanium implants reduces the adverse effects and avoids undesirable effects., Competing Interests: None

Highly active, cost-effective and durable electrocatalysts for the oxygen reduction reaction (ORR) are critically important for renewable energy conversion and storage. Here we report a 3D bicontinuous nitrogen doped nanoporous graphene electrocatalyst co-anchoring with atomically dispersed nickel and copper atoms ((Ni,Cu)-NG) as a highly active single-atom ORR catalyst, fabricated by the combination of chemical vapor deposition and high temperature gas transportation. The resultant (Ni,Cu)-NG exhibits an exceptional ORR activity in alkaline electrolytes, comparable to the Pt-based benchmarks, from the synergistic effect of the CuNx and NiNx complexes. Endowed with high catalytic activity and outstanding durability under harsh electrochemical environments, rechargeable zinc-air batteries using (Ni,Cu)-NG as the cathodes show excellent energy efficiency (voltage gap of 0.74 V), large power density (150.6 mW cm-2 at 250 mA cm-2) and high cycling stability (>500 discharge-charge cycles at 10 mA cm-2). This study may pave an efficient avenue for designing highly durable single-atom ORR catalysts for metal-air batteries.

Discovery of advanced soft-magnetic high entropy alloy (HEA) thin films are highly pursued to obtain unidentified functional materials. The figure of merit in current nanocrystalline HEA thin films relies in integration of a simple single-step electrochemical approach with a complex HEA system containing multiple elements with dissimilar crystal structures and large variation of melting points. A new family of Cobalt-Copper-Iron-Nickel-Zinc (Co-Cu-Fe-Ni-Zn) HEA thin films are prepared through pulse electrodeposition in aqueous medium, hosts nanocrystalline features in the range of ~ 5-20 nm having FCC and BCC dual phases. The fabricated Co-Cu-Fe-Ni-Zn HEA thin films exhibited high saturation magnetization value of ~ 82 emu/g, relatively low coercivity value of 19.5 Oe and remanent magnetization of 1.17%. Irrespective of the alloying of diamagnetic Zn and Cu with ferromagnetic Fe, Co, Ni elements, the HEA thin film has resulted in relatively high saturation magnetization which can provide useful insights for its potential unexplored applications.

Prolonged exposure to Ultra Violet Radiation (UVR) adversely alters the functions of many skin cell types causing skin cancer and photoaging, which had led to increase in demand for more safe and natural sunscreens against UVR. The present study focuses on production, structural characterization and evaluation of photoprotective nature of melanin pigment derived from lime dwelling Pseudomonas sp. Melanin was characterized by solubility, UV-Vis, FT-IR, 13 C-CPMAS, ESI-MS spectroscopy, including particle size, melting point and elemental analyses. In vitro cytotoxicity and photo-protective effect of Pseudomonas derived melanin (Mel-P) against UV-B (Broad Band-BB) radiations were assessed on mouse fibroblasts NIH 3 T3 cell lines. Reactive Oxygen Species (ROS) generated in NIH 3 T3 cells upon UV-B (BB) exposure was determined and quantified by Fluorescent microscopic and Flow cytometric analyses. A natural melanin obtained from Pseudomonas sp. contains 5,6- dihydroxy indole 2-carboxyic acid (DHICA) as its basic constituent and possess typical properties of eumelanin as revealed by the characterization studies. Mel-P has shown cell viability of 61.33 ± 6.58% at the concentration of 500 μg/mL proving its non-cytotoxic effect. Owing to its anti-oxidant property, melanin efficiently protected the mouse fibroblast cells from UV-B (BB) irradiation in a dose dependant manner demonstrating its potential as an active photoprotective agent., (Copyright © 2021 Elsevier B.V. All rights reserved.)

The failure of superhard materials is often associated with stress-induced amorphization. However, the underlying mechanisms of the structural evolution remain largely unknown. Here, we report the experimental measurements of the onset of shear amorphization in single-crystal boron carbide by nanoindentation and transmission electron microscopy. We verified that rate-dependent loading discontinuity, i.e., pop-in, in nanoindentation load-displacement curves results from the formation of nanosized amorphous bands via shear amorphization. Stochastic analysis of the pop-in events reveals an exceptionally small activation volume, slow nucleation rate, and lower activation energy of the shear amorphization, suggesting that the high-pressure structural transition is activated and initiated by dislocation nucleation. This dislocation-mediated amorphization has important implications in understanding the failure mechanisms of superhard materials at stresses far below their theoretical strengths., (Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).)

Introduction: Deep brain stimulation of the zona incerta is effective at treating tremor and other forms of parkinsonism. However, the structure is not well visualized with standard MRI protocols making direct surgical targeting unfeasible and contributing to inconsistent clinical outcomes. In this study, we applied coronal gradient echo MRI to directly visualize the rostral zona incerta in Parkinson's disease patients to improve targeting for deep brain stimulation., Methods: We conducted a prospective study to optimize and evaluate an MRI sequence to visualize the rostral zona incerta in patients with Parkinson's disease (n = 31) and other movement disorders (n = 13). We performed a contrast-to-noise ratio analysis of specific regions of interest to quantitatively assess visual discrimination of relevant deep brain structures in the optimized MRI sequence. Regions of interest were independently assessed by 2 neuroradiologists, and interrater reliability was assessed., Results: Rostral zona incerta and subthalamic nucleus were well delineated in our 5.5-min MRI sequence, indicated by excellent interrater agreement between neuroradiologists for region-of-interest measurements (>0.90 intraclass coefficient). Mean contrast-to-noise ratio was high for both rostral zona incerta (6.39 ± 3.37) and subthalamic nucleus (17.27 ± 5.61) relative to adjacent white matter. There was no significant difference between mean signal intensities or contrast-to-noise ratio for Parkinson's and non-Parkinson's patients for either structure., Discussion/conclusion: Our optimized coronal gradient echo MRI sequence delineates subcortical structures relevant to traditional and novel deep brain stimulation targets, including the zona incerta, with high contrast-to-noise. Future studies will prospectively apply this sequence to surgical planning and postimplantation outcomes., (© 2021 S. Karger AG, Basel.)

The structural characterization of sublayer surfaces of MIL-101 is reported by low-dose spherical aberration-corrected high-resolution transmission electron microscopy (HRTEM). The state-of-the-art microscopy directly images atomic/molecular configurations in thin crystals from charge density projections, and uncovers the structures of sublayer surfaces and their evolution to stable surfaces regulated by inorganic Cr 3 (μ 3 -O) trimers. This study provides compelling evidence of metal-organic frameworks (MOFs) crystal growth via the assembly of sublayer surfaces and has important implications in understanding the crystal growth and surface-related properties of MOFs., (© 2020 Wiley-VCH GmbH.)

Background: Hypertension is the biggest contributor to global burden of disease and mortality. Increasing compliance with antihypertensive treatment and achieving a wide BP control in the population represents a major challenge for clinical practice. The benefits of single pill combination versus free-equivalent combination has been demonstrated in several meta-analyses and is now strongly supported by the latest 2018 ESC/ESH guidelines. The RAAS blocker with CCB and thiazide like diuretic is proposed as the optimal combination in patients inadequately controlled by two drugs., Objective: To assess the blood pressure control rate, safety, tolerability and quality of life with triple-drug SPC in patients with grade II/ III hypertension., Methods: Hypertensive patients uncontrolled (BP ≥ 140/90 mmHg) on two-drug therapy were recruited in an open-label, phase III clinical trial conducted in outpatient setting in India with 6 months treatment period. No other antihypertensive medication except the study medication was received by the patients., Results: Out of 218 evaluable patients the observed average blood pressure reduction achieved from baseline to end of study at 6 months was Systolic Blood Pressure (SBP) 28.5 mm Hg / Diastolic Blood Pressure (DBP) 13.8 mm Hg. The quality of life (QoL) questionnaire demonstrated improvement in QoL for all patients., Conclusion: This study showed the clinical efficacy, safety and acceptability of the perindopril/indapamide/amlodipine SPC in patients with grade 2/3 hypertension inadequately controlled with two-drug therapy. The clinical effectiveness was observed in more than 96 % patients. The benefit of single-pill combination (SPC) therapy in hypertension control was reconfirmed in this study., (© Journal of the Association of Physicians of India 2011.)