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18 results on '"Ramdani Yanis"'

8. IgA Vasculitis Following COVID-19 Vaccination: A French Multicenter Case Series Including 12 Patients

Author

Ramdani, Yanis, primary, Bettuzzi, Thomas, additional, Bouznad, Amel, additional, Delaitre, Léa, additional, Nassarmadji, Kladoum, additional, Didier, Kevin, additional, Paul, Carle, additional, Liozon, Eric, additional, Tieu, Ashley, additional, Richard-Colmant, Gaëlle, additional, Terrier, Benjamin, additional, Moulis, Guillaume, additional, Lafaurie, Margaux, additional, Pillebout, Evangeline, additional, Maillot, François, additional, and Audemard-Verger, Alexandra, additional

Published
2022
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9. Immunoglobulin A Vasculitis Following COVID-19: A French Multicenter Case Series

Author

Ramdani, Yanis, primary, Galempoix, Jean Marc, additional, Augusto, Jean François, additional, Dekmeer, Eva, additional, Perard, Laurent, additional, Ferreira, Nicole, additional, Bigot, Adrien, additional, Magnant, Julie, additional, Jobard, Stéphanie, additional, Diot, Elisabeth, additional, Besse, Marie Charlotte, additional, Henrique, Hélène, additional, Maillot, François, additional, and Audemard-Verger, Alexandra, additional

Published
2022
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13. A Specific Diagnostic Metabolome Signature in Adult IgA Vasculitis

Author

Boissais, Alexandre, primary, Blasco, Hélène, additional, Emond, Patrick, additional, Lefevre, Antoine, additional, Bigot, Adrien, additional, Ramdani, Yanis, additional, Ferreira-Maldent, Nicole, additional, Mulleman, Denis, additional, Pillebout, Evangéline, additional, Maillot, Francois, additional, and Audemard-Verger, Alexandra, additional

Published
2022
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14. Neonatal Fc receptor expression in lymphoid and myeloid cells in systemic lupus erythematosus

Author

François Maillot, Nicole Ferreira-Maldent, Barbet Christelle, Pauline Beurier, Elisabeth Diot, Adrien Bigot, Cécile Bergua, Ramdani Yanis, and Valérie Gouilleux-Gruart

Subjects
Adult, Male, Adolescent, Lupus nephritis, Receptors, Fc, Monocytes, Young Adult, Neonatal Fc receptor, Rheumatology, immune system diseases, Medicine, Humans, Lupus Erythematosus, Systemic, skin and connective tissue diseases, Child, Aged, business.industry, Histocompatibility Antigens Class I, Receptors, IgG, Albumin, Middle Aged, medicine.disease, Pathophysiology, Case-Control Studies, Myeloid cells, Immunology, Female, business, Biomarkers
Abstract

The neonatal Fc receptor (FcRn) is a ubiquitously expressed protein historically involved in IgG and albumin recycling. Recent data suggest an involvement in the pathophysiology of antibody-mediated autoimmune diseases. Among them, systemic lupus erythematosus (SLE) implies clinical and biological abnormalities of innate and adaptive circulating immune cells, potentially involving newly described functions of FcRn. In this study, FcRn expression was assessed by flow cytometry in peripheral blood leukocytes of 41 SLE patients with either active or inactive disease and 32 healthy donors. FcRn expression in B cells, natural killer cells, and T cells of SLE patients was statistically lower as compared to healthy donors. Conversely, FcRn level was statistically higher in non-classical monocyte subpopulations (CD14+CD16+ monocytes) of SLE patients versus healthy donors providing an interesting perspective to further explore its role in SLE pathophysiology.

Published
2021

17. Impact of gender on baseline presentation and outcome in adult IgA vasculitis.

Author

Baud KL, Hankard A, Ramdani Y, Maisons V, Pillebout E, Augusto JF, Jourde-Chiche N, Faguer S, Ferreira-Maldent N, Maillot F, Halimi JM, Terrier B, and Audemard-Verger A

Abstract

Objectives: Adult IgA vasculitis (IgAV) is more common in males, but the potential impact of gender remains unclear. We aimed to describe the impact of gender on presentation and outcome in adult IgAV., Methods: We retrospectively analysed data from a multicentre retrospective cohort of 260 patients (IGAVAS). Comparisons were made according to gender status., Results: Data from 259 patients (95 females and 164 males) were analysed. Compared with females, baseline presentation in males was similar for cutaneous involvement (100% vs 100%, p= 1.0), joint involvement (60% vs 63%, p= 0.7), gastrointestinal involvement (57% vs 45%, p= 0.093) and glomerulonephritis (73% vs 64%, p= 0.16). Glomerulonephritis was more severe at baseline in males than in females, with a lower median estimated glomerular filtration rate (eGFR) (90 [IQR 59-105] vs 97 ml/min/1.73m2 [76-116], p= 0.015) and increased median proteinuria (0.84 vs 0.58 g/day, p= 0.01). There were no differences in histological findings in patients who had a kidney biopsy. Methylprednisolone was more frequently used in males (40% vs22%, p= 0.015), as were immunosuppressants, especially cyclophosphamide 24% vs 6%, p= 0.0025) and azathioprine (10% vs 2%, p= 0.038). Analysis of treatment response showed that males had more frequent refractory disease (30% vs 13%, p= 0.004). Long-term outcomes (mortality and progression to chronic kidney failure) did not differ., Conclusion: Kidney involvement in IgAV appears to more severe in males, which is supported by more intensive treatment contrasting with a lower response rate. This study raises the question of gender as a new prognostic factor in adult IgAV., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.)

Published
2023
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18. [Scurvy mimicking vasculitis].

Author

Maillet C, Wong So J, Ramdani Y, Bigot A, Ferreira-Maldent N, Chandenier B, Maillot F, and Audemard-Verger A

Subjects
Humans, Diagnosis, Differential, Ascorbic Acid, Scurvy diagnosis, Vasculitis diagnosis
Published
2023

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