1. Cancer-ID: Toward Identification of Cancer by Tumor-Derived Extracellular Vesicles in Blood
- Author
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L. G. Rikkert, P. Beekman, J. Caro, F. A. W. Coumans, A. Enciso-Martinez, G. Jenster, S. Le Gac, W. Lee, T. G. van Leeuwen, G. B. Loozen, A. Nanou, R. Nieuwland, H. L. Offerhaus, C. Otto, D. M. Pegtel, M. C. Piontek, E. van der Pol, L. de Rond, W. H. Roos, R. B. M. Schasfoort, M. H. M. Wauben, H. Zuilhof, and L. W. M. M. Terstappen
- Subjects
atomic force microscopy ,electrochemistry ,electron microscopy ,extracellular vesicles ,flow cytometry ,fluorescence microscopy ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Extracellular vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state dependent and their cargo can contain disease-related information. Large tumor-derived EVs (tdEVs, >1 μm) in blood from cancer patients are associated with poor outcome, and changes in their number can be used to monitor therapy effectiveness. Whereas, small tumor-derived EVs (
- Published
- 2020
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