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Cancer-ID: Toward Identification of Cancer by Tumor-Derived Extracellular Vesicles in Blood

Authors :
L. G. Rikkert
P. Beekman
J. Caro
F. A. W. Coumans
A. Enciso-Martinez
G. Jenster
S. Le Gac
W. Lee
T. G. van Leeuwen
G. B. Loozen
A. Nanou
R. Nieuwland
H. L. Offerhaus
C. Otto
D. M. Pegtel
M. C. Piontek
E. van der Pol
L. de Rond
W. H. Roos
R. B. M. Schasfoort
M. H. M. Wauben
H. Zuilhof
L. W. M. M. Terstappen
Source :
Frontiers in Oncology, Vol 10 (2020)
Publication Year :
2020
Publisher :
Frontiers Media S.A., 2020.

Abstract

Extracellular vesicles (EVs) have great potential as biomarkers since their composition and concentration in biofluids are disease state dependent and their cargo can contain disease-related information. Large tumor-derived EVs (tdEVs, >1 μm) in blood from cancer patients are associated with poor outcome, and changes in their number can be used to monitor therapy effectiveness. Whereas, small tumor-derived EVs (

Details

Language :
English
ISSN :
2234943X
Volume :
10
Database :
Directory of Open Access Journals
Journal :
Frontiers in Oncology
Publication Type :
Academic Journal
Accession number :
edsdoj.082acfe9a39b48b295204f818f431623
Document Type :
article
Full Text :
https://doi.org/10.3389/fonc.2020.00608