271,682 results on '"Quinn A."'
Search Results
2. Consequences of gene editing of PRLR on thermotolerance, growth, and male reproduction in cattle
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Camila J. Cuellar, Thiago F. Amaral, Paula Rodriguez‐Villamil, F. Ongaratto, D. Onan Martinez, Rémi Labrecque, João D. de Agostini Losano, Eliab Estrada‐Cortés, Jonathan R. Bostrom, Kyra Martins, D. Owen Rae, Jeremy Block, Quinn A. Hoorn, Bradford W. Daigneault, Jonathan Merriam, Michael Lohuis, Serdal Dikmen, João H. J. Bittar, Tatiane S. Maia, Daniel F. Carlson, Sabreena Larson, Tad S. Sonstegard, and Peter J. Hansen
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cattle ,gene editing ,PRLR ,slick allele ,thermotolerance ,Biology (General) ,QH301-705.5 - Abstract
Abstract Global warming is a major challenge to the sustainable and humane production of food because of the increased risk of livestock to heat stress. Here, the example of the prolactin receptor (PRLR) gene is used to demonstrate how gene editing can increase the resistance of cattle to heat stress by the introduction of mutations conferring thermotolerance. Several cattle populations in South and Central America possess natural mutations in PRLR that result in affected animals having short hair and being thermotolerant. CRISPR/Cas9 technology was used to introduce variants of PRLR in two thermosensitive breeds of cattle – Angus and Jersey. Gene‐edited animals exhibited superior ability to regulate vaginal temperature (heifers) and rectal temperature (bulls) compared to animals that were not gene‐edited. Moreover, gene‐edited animals exhibited superior growth characteristics and had larger scrotal circumference. There was no evidence for deleterious effects of the mutation on carcass characteristics or male reproductive function. These results indicate the potential for reducing heat stress in relevant environments to enhance cattle productivity.
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- 2024
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3. Kinetically controlled metal-elastomer nanophases for environmentally resilient stretchable electronics
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Soosang Chae, Won Jin Choi, Lisa Julia Nebel, Chang Hee Cho, Quinn A. Besford, André Knapp, Pavlo Makushko, Yevhen Zabila, Oleksandr Pylypovskyi, Min Woo Jeong, Stanislav Avdoshenko, Oliver Sander, Denys Makarov, Yoon Jang Chung, Andreas Fery, Jin Young Oh, and Tae Il Lee
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Science - Abstract
Abstract Nanophase mixtures, leveraging the complementary strengths of each component, are vital for composites to overcome limitations posed by single elemental materials. Among these, metal-elastomer nanophases are particularly important, holding various practical applications for stretchable electronics. However, the methodology and understanding of nanophase mixing metals and elastomers are limited due to difficulties in blending caused by thermodynamic incompatibility. Here, we present a controlled method using kinetics to mix metal atoms with elastomeric chains on the nanoscale. We find that the chain migration flux and metal deposition rate are key factors, allowing the formation of reticular nanophases when kinetically in-phase. Moreover, we observe spontaneous structural evolution, resulting in gyrified structures akin to the human brain. The hybridized gyrified reticular nanophases exhibit strain-invariant metallic electrical conductivity up to 156% areal strain, unparalleled durability in organic solvents and aqueous environments with pH 2–13, and high mechanical robustness, a prerequisite for environmentally resilient devices.
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- 2024
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4. Identification of quantitative trait loci and associated candidate genes for pregnancy success in Angus–Brahman crossbred heifers
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Quinn A. Hoorn, Gabriel A. Zayas, Eduardo E. Rodriguez, Laura M. Jensen, Raluca G. Mateescu, and Peter J. Hansen
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Beef cattle ,Fertility ,GWAS ,QTL ,Animal culture ,SF1-1100 ,Veterinary medicine ,SF600-1100 - Abstract
Abstract Background In beef cattle, more than 50% of the energy input to produce a unit of beef is consumed by the female that produced the calf. Development of genomic tools to identify females with high genetic merit for reproductive function could increase the profitability and sustainability of beef production. Results Genome-wide association studies (GWAS) were performed using a single-step genomic best linear unbiased prediction approach on pregnancy outcome traits from a population of Angus–Brahman crossbred heifers. Furthermore, a validation GWAS was performed using data from another farm. Heifers were genotyped with the Bovine GGP F250 array that contains 221,077 SNPs. In the discovery population, heifers were bred in winter breeding seasons involving a single round of timed artificial insemination (AI) followed by natural mating for 3 months. Two phenotypes were analyzed: pregnancy outcome to first-service AI (PAI; n = 1,481) and pregnancy status at the end of the breeding season (PEBS; n = 1,725). The heritability was estimated as 0.149 and 0.122 for PAI and PEBS, respectively. In the PAI model, one quantitative trait locus (QTL), located between 52.3 and 52.5 Mb on BTA7, explained about 3% of the genetic variation, in a region containing a cluster of γ-protocadherin genes and SLC25A2. Other QTLs explaining between 0.5% and 1% of the genetic variation were found on BTA12 and 25. In the PEBS model, a large QTL on BTA7 was synonymous with the QTL for PAI, with minor QTLs located on BTA5, 9, 10, 11, 19, and 20. The validation population for pregnancy status at the end of the breeding season were Angus–Brahman crossbred heifers bred by natural mating. In concordance with the discovery population, the large QTL on BTA7 and QTLs on BTA10 and 12 were identified. Conclusions In summary, QTLs and candidate SNPs identified were associated with pregnancy outcomes in beef heifers, including a large QTL associated with a group of protocadherin genes. Confirmation of these associations with larger populations could lead to the development of genomic predictions of reproductive function in beef cattle. Moreover, additional research is warranted to study the function of candidate genes associated with QTLs.
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- 2023
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5. Changes in peripheral oxytocin and vasopressin during a silent month-long Insight meditation retreat
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Quinn A. Conklin, Anthony P. Zanesco, Brandon G. King, Elissa S. Epel, and Clifford D. Saron
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meditation ,oxytocin ,vasopressin ,prosociality ,social interaction ,attachment style ,Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
BackgroundGiven its putative roles in mediating prosocial behavior, attachment bonds, and stress physiology, oxytocin modulation has been hypothesized to be a biological correlate of the salubrious effects of meditation practice. Here we investigated the effects of a month-long silent meditation retreat on changes in oxytocin, and the related hormone and vasopressin, in relation to psychosocial changes in attachment style, anxiety, personality measures, and feelings of social connectedness with fellow meditators.MethodsPlasma oxytocin and vasopressin and self-report questionnaires were measured in retreat participants (n = 28) at the beginning of, and 3 weeks into, a residential meditation retreat. Control participants (n = 34), who were similar in age, gender, and meditation experience, were also assessed across a 3-week interval. Linear mixed effects models were used to assess outcomes.ResultsThe retreat group showed a small but significant decrease in oxytocin compared to controls who showed no change. In the retreat group, higher openness to experience at Time 1 predicted greater reductions in oxytocin during the retreat, and lower oxytocin at Time 2 was related to stronger feelings of personal connection with fellow meditators. The changes in oxytocin were not related to attachment style or anxiety. Vasopressin decreased over time across both groups, suggesting no specific effect of retreat.ConclusionThese preliminary findings suggest that meditation training in the context of a silent residential retreat may reduce circulating levels of oxytocin. We interpret this finding from multiple theoretical perspectives, discussing key measurement limitations and proposing future study designs that may help to differentiate the effects of different meditation practices and contexts on oxytocin signaling.
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- 2024
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6. Fucik spectrum with weights and existence of solutions for nonlinear elliptic equations with nonlinear boundary conditions
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Nsoki Mavinga, Quinn A. Morris, and Stephen B. Robinson
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fucik spectrum ,resonance ,nonlinear boundary condition ,Mathematics ,QA1-939 - Published
- 2023
7. Integrated FRET Polymers Spatially Reveal Micro‐ to Nanostructure and Irregularities in Electrospun Microfibers
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Xiaojian Liao, Dmitrii Sychev, Khrystyna Rymsha, Mahmoud Al‐Hussein, José Paulo Farinha, Andreas Fery, and Quinn A. Besford
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conformation reporting ,electrospinning ,FRET ,messenger materials ,polymers ,Science - Abstract
Abstract A spatial view of macroscopic polymer material properties, in terms of nanostructure and irregularities, can help to better understand engineering processes such as when materials may fail. However, bridging the gap between the molecular‐scale arrangement of polymer chains and the spatially resolved macroscopic properties of a material poses numerous difficulties. Herein, an integrated messenger material that can report on the material micro‐ to nanostructure and its processes is introduced. It is based on polymer chains labeled with fluorescent dyes that feature Förster resonance energy transfer (FRET) dependent on chain conformation and concentration within a host polymer material. These FRET materials are integrated within electrospun polystyrene microfibers, and the FRET is analyzed by confocal laser scanning microscopy (CLSM). Importantly, the use of CLSM allows a spatial view of material nanostructure and irregularities within the microfibers, where changes in FRET are significant when differences in fiber geometries and regularities exist. Furthermore, changes in FRET observed in damaged regions of the fibers indicate changes in polymer conformation and/or concentration as the material changes during compression. The system promises high utility for applications where nano‐to‐macro communication is needed for a better understanding of material processes.
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- 2023
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8. Implementing Equity Policies in Illinois Higher Education Institutions: The Illinois Equity in Attainment Initiative
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NORC at the University of Chicago, Fordham University, Rachel Carly Feldman, Johanna S. Quinn, Alannah S. Caisey, and Carol Chen
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The Partnership for College Completion (PCC) was founded to "advance equity in higher education" by supporting colleges and universities to improve college completion for Black, Latinx, and Pell-eligible students--those groups that experience persistent disparities in completion. Simultaneously, PCC engages in state policy reform to bring about systems-wide change. Begun in 2018, the Illinois Equity in Attainment Initiative (ILEA) is its flagship initiative, designed to partner with Illinois colleges and universities to assist them in narrowing their college completion gaps. Promising new research suggests improving equity in college completion requires an explicit focus on race, attention to organizational change, commitment to equity-focused policies and plans, and cross-institutional partnerships to help manifest change. Drawing from this research, ILEA and its partner institutions developed and implemented public-facing equity plans to improve graduation rates for their Black, Latinx, and Pell-eligible students. This study examines how the ILEA collaborative institutions confronted and negotiated structural barriers inhibiting graduation for these historically marginalized groups. The report aims to: (1) Provide study partners, including the Partnership for College Completion, with program feedback; (2) Inform readers about equity plan development and implementation, policy, and practice collaboratives; (3) Identify strengths and growth opportunities about PCC's efforts to bring colleges and universities together to jointly improve college completion for Black, Latinx, and Pell-eligible students; and (4) Reflect on implementation successes and challenges.
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- 2024
9. Species diversity and molecular characterization of Alternaria section Alternaria isolates collected mainly from cereal crops in Canada
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Jeremy R. Dettman, Quinn A. Eggertson, and Natalie E. Kim
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Alternaria alternata ,A. arborescens ,ASA-10 ,ASA-19 ,RPB2 ,species complex ,Microbiology ,QR1-502 - Abstract
Alternaria is often one on the most abundant fungal genera recovered from a wide array of plant hosts and environmental substrates. Many species within the sub-generic Alternaria section Alternaria are common plant pathogens that cause pre-harvest losses due to reduced productivity and post-harvest losses due to spoilage and contamination with mycotoxins. As certain species of Alternaria may have distinct mycotoxin profiles, and very broad host ranges, understanding the distribution of species by geography and host is critical for disease prediction, toxicological risk assessment, and guiding regulatory decisions. In two previous reports, we performed phylogenomic analyses to identify highly informative molecular markers for Alternaria section Alternaria, and validated their diagnostic ability. Here, we perform molecular characterization of 558 section Alternaria strains, collected from 64 host genera in 12 countries, using two of these section-specific loci (ASA-10 and ASA-19) along with the RNA polymerase II second largest subunit (rpb2) gene. The majority of strains (57.4%) originated from various cereal crops in Canada, which formed the main focus of our study. Phylogenetic analyses were used to classify strains into section Alternaria species/lineages, demonstrating that the most common species on Canadian cereal crops are Alternaria alternata and A. arborescens. Further population genetic analyses were consistent with A. alternata being a widely distributed species with relatively low levels of geographic isolation (i.e., Canadian isolates did not form distinct clades when compared to other regions). Our expanded sampling of A. arborescens has greatly increased the known diversity of this group, with A. arborescens isolates forming at least three distinct phylogenetic lineages. Proportionally, A. arborescens is more prevalent in Eastern Canada than in Western Canada. Sequence analyses, putative hybrids, and mating-type distributions provided some evidence for recombination events, both within and between species. There was little evidence for associations between hosts and genetic haplotypes of A. alternata or A. arborescens.
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- 2023
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10. Study protocol: cluster randomized trial of consultation strategies for the sustainment of mental health interventions in under-resourced urban schools: rationale, design, and methods
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Ricardo Eiraldi, Barry L. McCurdy, Muniya S. Khanna, Courtney Benjamin Wolk, Henry A. Glick, Quinn A. Rabenau-McDonnell, Rachel Comly, Laura E. Rutherford, Jayme Banks, Steven A. Rufe, Kristina M. Popkin, Tara Wilson, Kathryn Henson, Abraham Wandersman, and Abbas F. Jawad
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Sustainment ,Implementation ,PBIS ,Mental health supports ,Urban schools ,Effectiveness ,Psychology ,BF1-990 - Abstract
Abstract Background The school is a key setting for the provision of mental health services to children, particularly those underserved through traditional service delivery systems. School-wide Positive Behavioral Interventions and Supports (PBIS) is a tiered approach to service delivery based on the public health model that schools use to implement universal (Tier 1) supports to improve school climate and safety. As our prior research has demonstrated, PBIS is a useful vehicle for implementing mental and behavioral health evidence-based practices (EBPs) at Tier 2 for children with, or at risk for, mental health disorders. Very little research has been conducted regarding the use of mental health EBPs at Tier 2 or how to sustain implementation in schools. Methods/design The main aim of the study is to compare fidelity, penetration, cost-effectiveness, and student outcomes of Tier 2 mental health interventions across 2 sustainment approaches for school implementers in 12 K-8 schools. The study uses a 2-arm, cluster randomized controlled trial design. The two arms are: (a) Preparing for Sustainment (PS)—a consultation strategy implemented by school district coaches who receive support from external consultants, and (b) Sustainment as Usual (SAU)—a consultation strategy implemented by school district coaches alone. Participants will be 60 implementers and 360 students at risk for externalizing and anxiety disorders. The interventions implemented by school personnel are: Coping Power Program (CPP) for externalizing disorders, CBT for Anxiety Treatment in Schools (CATS) for anxiety disorders, and Check-in/Check-out (CICO) for externalizing and internalizing disorders. The Interactive Systems Framework (ISF) for Dissemination and Implementation guides the training and support procedures for implementers. Discussion We expect that this study will result in a feasible, effective, and cost-effective strategy for sustaining mental health EBPs that is embedded within a multi-tiered system of support. Results from this study conducted in a large urban school district would likely generalize to other large, urban districts and have an impact on population-level child mental health. Trial registration ClinicalTrials.gov identifier number NCT04869657. Registered May 3, 2021.
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- 2022
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11. Scalable and Accurate Application-Level Crash-Consistency Testing via Representative Testing
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Gu, Yile, Neal, Ian, Xu, Jiexiao, Lee, Shaun Christopher, Said, Ayman, Haydar, Musa, Van Geffen, Jacob, Kadekodi, Rohan, Quinn, Andrew, and Kasikci, Baris
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Computer Science - Operating Systems ,Computer Science - Programming Languages ,Computer Science - Software Engineering - Abstract
Crash consistency is essential for applications that must persist data. Crash-consistency testing has been commonly applied to find crash-consistency bugs in applications. The crash-state space grows exponentially as the number of operations in the program increases, necessitating techniques for pruning the search space. However, state-of-the-art crash-state space pruning is far from ideal. Some techniques look for known buggy patterns or bound the exploration for efficiency, but they sacrifice coverage and may miss bugs lodged deep within applications. Other techniques eliminate redundancy in the search space by skipping identical crash states, but they still fail to scale to larger applications. In this work, we propose representative testing: a new crash-state space reduction strategy that achieves high scalability and high coverage. Our key observation is that the consistency of crash states is often correlated, even if those crash states are not identical. We build Pathfinder, a crash-consistency testing tool that implements an update behaviors-based heuristic to approximate a small set of representative crash states. We evaluate Pathfinder on POSIX-based and MMIO-based applications, where it finds 18 (7 new) bugs across 8 production-ready systems. Pathfinder scales more effectively to large applications than prior works and finds 4x more bugs in POSIX-based applications and 8x more bugs in MMIO-based applications compared to state-of-the-art systems., Comment: OOPSLA 2025
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- 2025
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12. Spatial Analysis of Neuromuscular Junctions Activation in Three-Dimensional Histology-based Muscle Reconstructions
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Orsini, Alessandro Ascani, Bhatt, Manan, Perkins, Pierce L., Wang, Siyu, Quinn, Kiara N., Griffith, Kenzi, Kang, Fausto, and Thakor, Nitish V.
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Quantitative Biology - Quantitative Methods - Abstract
Histology has long been a foundational technique for studying anatomical structures through tissue slicing. Advances in computational methods now enable three dimensional (3D) reconstruction of organs from histology images, enhancing the analysis of structural and functional features. Here, we present a novel multimodal computational method to reconstruct rodent muscles in 3D using classical image processing and data analysis techniques, analyze their structural features and correlate them to previously recorded electrophysiological data. The algorithm analyzes spatial distribution patterns of features identified through histological staining, normalizing them across multiple samples. Further, the algorithm successfully correlates spatial patterns with high density epimysial ElectroMyoGraphy (hdEMG) recordings, providing a multimodal perspective on neuromuscular dynamics, linking spatial and electrophysiological information. The code was validated by looking at the distribution of NeuroMuscular Junctions (NMJs) in naive soleus muscles and compared the distributions and patterns observed with ones observed in previous literature. Our results showed consistency with the expected results, validating our method for features and pattern recognition. The multimodal aspect was shown in a naive soleus muscle, where a strong correlation was found between motor unit locations derived via hdEMG, and NMJ locations obtained from histology, highlighting their spatial relationship. This multimodal analysis tool integrates 3D structural data with electrophysiological activity, opening new avenues in muscle diagnostics, regenerative medicine, and personalized therapies where spatial insights could one day predict electrophysiological behavior or vice versa., Comment: 31 pages, 6 figures, for associated codes see: https://github.com/AleAsca/Histology-NMJ-and-muscle-Activity-Toolbox
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- 2025
13. Roadmap to fault tolerant quantum computation using topological qubit arrays
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Aasen, David, Aghaee, Morteza, Alam, Zulfi, Andrzejczuk, Mariusz, Antipov, Andrey, Astafev, Mikhail, Avilovas, Lukas, Barzegar, Amin, Bauer, Bela, Becker, Jonathan, Bello-Rivas, Juan M., Bhaskar, Umesh, Bocharov, Alex, Boddapati, Srini, Bohn, David, Bommer, Jouri, Bonderson, Parsa, Borovsky, Jan, Bourdet, Leo, Boutin, Samuel, Brown, Tom, Campbell, Gary, Casparis, Lucas, Chakravarthi, Srivatsa, Chao, Rui, Chapman, Benjamin J., Chatoor, Sohail, Christensen, Anna Wulff, Codd, Patrick, Cole, William, Cooper, Paul, Corsetti, Fabiano, Cui, Ajuan, van Dam, Wim, Dandachi, Tareq El, Daraeizadeh, Sahar, Dumitrascu, Adrian, Ekefjärd, Andreas, Fallahi, Saeed, Galletti, Luca, Gardner, Geoff, Gatta, Raghu, Gavranovic, Haris, Goulding, Michael, Govender, Deshan, Griggio, Flavio, Grigoryan, Ruben, Grijalva, Sebastian, Gronin, Sergei, Gukelberger, Jan, Haah, Jeongwan, Hamdast, Marzie, Hansen, Esben Bork, Hastings, Matthew, Heedt, Sebastian, Ho, Samantha, Hogaboam, Justin, Holgaard, Laurens, Van Hoogdalem, Kevin, Indrapiromkul, Jinnapat, Ingerslev, Henrik, Ivancevic, Lovro, Jablonski, Sarah, Jensen, Thomas, Jhoja, Jaspreet, Jones, Jeffrey, Kalashnikov, Kostya, Kallaher, Ray, Kalra, Rachpon, Karimi, Farhad, Karzig, Torsten, Kimes, Seth, Kliuchnikov, Vadym, Kloster, Maren Elisabeth, Knapp, Christina, Knee, Derek, Koski, Jonne, Kostamo, Pasi, Kuesel, Jamie, Lackey, Brad, Laeven, Tom, Lai, Jeffrey, de Lange, Gijs, Larsen, Thorvald, Lee, Jason, Lee, Kyunghoon, Leum, Grant, Li, Kongyi, Lindemann, Tyler, Lucas, Marijn, Lutchyn, Roman, Madsen, Morten Hannibal, Madulid, Nash, Manfra, Michael, Markussen, Signe Brynold, Martinez, Esteban, Mattila, Marco, Mattinson, Jake, McNeil, Robert, Mei, Antonio Rodolph, Mishmash, Ryan V., Mohandas, Gopakumar, Mollgaard, Christian, de Moor, Michiel, Morgan, Trevor, Moussa, George, Narla, Anirudh, Nayak, Chetan, Nielsen, Jens Hedegaard, Nielsen, William Hvidtfelt Padkær, Nolet, Frédéric, Nystrom, Mike, O'Farrell, Eoin, Otani, Keita, Paetznick, Adam, Papon, Camille, Paz, Andres, Petersson, Karl, Petit, Luca, Pikulin, Dima, Pons, Diego Olivier Fernandez, Quinn, Sam, Rajpalke, Mohana, Ramirez, Alejandro Alcaraz, Rasmussen, Katrine, Razmadze, David, Reichardt, Ben, Ren, Yuan, Reneris, Ken, Riccomini, Roy, Sadovskyy, Ivan, Sainiemi, Lauri, Saldaña, Juan Carlos Estrada, Sanlorenzo, Irene, Schaal, Simon, Schmidgall, Emma, Sfiligoj, Cristina, da Silva, Marcus P., Sinha, Sarat, Soeken, Mathias, Sohr, Patrick, Stankevic, Tomas, Stek, Lieuwe, Strøm-Hansen, Patrick, Stuppard, Eric, Sundaram, Aarthi, Suominen, Henri, Suter, Judith, Suzuki, Satoshi, Svore, Krysta, Teicher, Sam, Thiyagarajah, Nivetha, Tholapi, Raj, Thomas, Mason, Tom, Dennis, Toomey, Emily, Tracy, Josh, Troyer, Matthias, Turley, Michelle, Turner, Matthew D., Upadhyay, Shivendra, Urban, Ivan, Vaschillo, Alexander, Viazmitinov, Dmitrii, Vogel, Dominik, Wang, Zhenghan, Watson, John, Webster, Alex, Weston, Joseph, Williamson, Timothy, Winkler, Georg W., van Woerkom, David J., Wütz, Brian Paquelet, Yang, Chung Kai, Yu, Richard, Yucelen, Emrah, Zamorano, Jesús Herranz, Zeisel, Roland, Zheng, Guoji, Zilke, Justin, and Zimmerman, Andrew
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Quantum Physics ,Condensed Matter - Superconductivity - Abstract
We describe a concrete device roadmap towards a fault-tolerant quantum computing architecture based on noise-resilient, topologically protected Majorana-based qubits. Our roadmap encompasses four generations of devices: a single-qubit device that enables a measurement-based qubit benchmarking protocol; a two-qubit device that uses measurement-based braiding to perform single-qubit Clifford operations; an eight-qubit device that can be used to show an improvement of a two-qubit operation when performed on logical qubits rather than directly on physical qubits; and a topological qubit array supporting lattice surgery demonstrations on two logical qubits. Devices that enable this path require a superconductor-semiconductor heterostructure that supports a topological phase, quantum dots and coupling between those quantum dots that can create the appropriate loops for interferometric measurements, and a microwave readout system that can perform fast, low-error single-shot measurements. We describe the key design components of these qubit devices, along with the associated protocols for demonstrations of single-qubit benchmarking, Clifford gate execution, quantum error detection, and quantum error correction, which differ greatly from those in more conventional qubits. Finally, we comment on implications and advantages of this architecture for utility-scale quantum computation., Comment: 11+6 pages, 8+5 figures
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- 2025
14. Higher-order continuum models for twisted bilayer graphene
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Quinn, Solomon, Kong, Tianyu, Luskin, Mitchell, and Watson, Alexander B.
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Mathematical Physics - Abstract
The first-order continuum PDE model proposed by Bistritzer and MacDonald in \cite{bistritzer2011moire} accurately describes the single-particle electronic properties of twisted bilayer graphene (TBG) at small twist angles. In this paper, we obtain higher-order corrections to the Bistritzer-MacDonald model via a systematic multiple-scales expansion. We prove that the solution of the resulting higher-order PDE model accurately approximates the corresponding tight-binding wave function under a natural choice of parameters and given initial conditions that are spectrally localized to the monolayer Dirac points. Numerical simulations of tight-binding and continuum dynamics demonstrate the validity of the higher-order continuum model. Symmetries of the higher-order models are also discussed. This work extends the analysis from \cite{watson2023bistritzer}, which rigorously established the validity of the (first-order) BM model.
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- 2025
15. Proving the Coding Interview: A Benchmark for Formally Verified Code Generation
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Dougherty, Quinn and Mehta, Ronak
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Computer Science - Software Engineering ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning ,Computer Science - Logic in Computer Science - Abstract
We introduce the Formally Verified Automated Programming Progress Standards, or FVAPPS, a benchmark of 4715 samples for writing programs and proving their correctness, the largest formal verification benchmark, including 1083 curated and quality controlled samples. Previously, APPS provided a benchmark and dataset for programming puzzles to be completed in Python and checked against unit tests, of the kind seen in technical assessments in the software engineering industry. Building upon recent approaches for benchmarks in interactive theorem proving, we generalize the unit tests to Lean 4 theorems given without proof (i.e., using Lean's "sorry" keyword). On the 406 theorems of 100 randomly selected samples, Sonnet correctly proves 30% and Gemini correctly proves 18%. We challenge the machine learning and program synthesis communities to solve both each general purpose programming problem and its associated correctness specifications. The benchmark is available at https://huggingface.co/datasets/quinn-dougherty/fvapps., Comment: 8 pages, to appear at the 2025LLM4Code Workshop at ICSE 2025
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- 2025
16. On the Orbit of the Binary Brown Dwarf Companion GL229 Ba and Bb
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Thompson, William, Blakely, Dori, Xuan, Jerry W., Bouchard-Côté, Alexandre, Bourdarot, Guillaume, Biron-Lattes, Miguel, Campbell, Trevor, Eisenhauer, Frank, Henning, Thomas, Janson, Markus, Johnstone, Doug, Kammerer, Jens, Konopacky, Quinn, Lacour, Sylvestre, Marois, Christian, Mawet, Dimitri, Mérand, Antoine, Nguyen, Jayke Samson, Nielsen, Eric, Rickman, Emily, Ruffio, Jean-Baptiste, Surjanovic, Nikola, Wang, Jason J., and Winterhalder, Thomas
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Astrophysics - Solar and Stellar Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
The companion GL229B was recently resolved by Xuan et al. (2024) as a tight binary of two brown dwarfs (Ba and Bb) through VLTI-GRAVITY interferometry and VLT-CRIRES+ RV measurements. Here, we present Bayesian models of the interferometric and RV data in additional detail, along with an updated outer orbit of the brown dwarf pair about the primary. To create a model of the inner orbit with robust uncertainties, we apply kernel phases to the GRAVITY data to address baseline redundancy in the raw closure phases. Using parallel tempering, we constrain the binary's orbit using only VLTI-GRAVITY data, despite each epoch having low visibility-plane coverage and/or SNR. We demonstrate very agreement the VLTI-GRAVITY and CRIRES+ datasets and find that the inner binary has a period of 12.1346$\pm$0.0011 days, eccentricity of 0.2317$\pm$0.0025, and total mass of 71.0$\pm$0.4 Mjup, with Ba and Bb having masses of 37.7$\pm$1.1Mjup and 33.4$\pm$1.0Mjup respectively. With new Keck/NIRC2 astrometry, we update the outer orbit GL229B around the primary. We find a semi-major axis of 42.9+3.0-2.4AU, eccentricity of 0.736$\pm$0.014, and a total mass for B of 71.7$\pm$0.6Mjup, consistent with that derived from the inner orbit. We find a mutual inclination of 31$\pm$2.5deg, below the threshold for Kozai-Lidov oscillations. The agreement on the mass of Ba+Bb between the inner and outer orbits is an important test of our ability to model RV, astrometry, and Hipparcos-Gaia proper motion anomaly. Our methodological advances in handling interferometric data with low SNR and sparse UV-coverage will benefit future observations of rapidly-orbiting companions with VLTI-GRAVITY., Comment: Resubmitted to AJ
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- 2025
17. VERITAS and multiwavelength observations of the Blazar B3 2247+381 in response to an IceCube neutrino alert
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Acharyya, Atreya, Adams, Colin B., Bangale, Priyadarshini, Bartkoske, J. T., Benbow, Wystan, Buckley, James H., Chen, Yu, Christiansen, Jodi, Chromey, Alisha, Duerr, Anne, Errando, Manel, Godoy, Miguel E., Falcone, Abe, Feng, Qi, Foote, Juniper, Fortson, Lucy, Furniss, Amy, Hanlon, William, Hanna, David, Hervet, Olivier, Hinrichs, Claire E., Holder, Jamie, Humensky, Thomas B., Jin, Weidong, Johnson, Madalyn N., Kaaret, Philip, Kertzman, Mary P., Kherlakian, Maria, Kieda, David, Kleiner, Tobias K., Korzoun, Mx. Nikolas, Krennrich, Frank, Kumar, Sajan, Lang, Mark J., Lundy, Matthew, McGrath, Conor, Meyer, Eileen T., Millard, Matthew J., Millis, John, Mooney, Connor, Moriarty, Patrick, Mukherjee, Reshmi, Ning, Wenmeng, O'Brien, Stephan, Ong, Rene A., Pohl, Martin, Pueschel, Elisa, Quinn, John, Rabinowitz, Pazit L., Ragan, Ken, Reynolds, Paul, Ribeiro, Deivid, Roache, Emmet Thomas, Ryan, Jamie L., Sadeh, Iftach, Sadun, Alberto, Saha, Lab, Santander, Marcos, Sembroski, Glenn H., Shang, Ruo-Yu, Splettstoesser, Megan, Tak, Donggeun, Talluri, Anjana K., Tucci, James V., Valverde, Janeth, Williams, David A., Wong, Sam L., Woo, Jooyun, Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S. K., Aguilar, J. A., Ahlers, M., Alameddine, J. M., Amin, N. M., Andeen, K., Argüelles, C., Ashida, Y., Athanasiadou, S., Axani, S. N., Babu, R., Bai, X., V., A. Balagopal, Baricevic, M., Barwick, S. W., Bash, S., Basu, V., Bay, R., Beatty, J. J., Tjus, J. Becker, Beise, J., Bellenghi, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D. Z., Blaufuss, E., Bloom, L., Blot, S., Bontempo, F., Motzkin, J. Y. Book, Meneguolo, C. Boscolo, Böser, S., Botner, O., Böttcher, J., Braun, J., Brinson, B., Brisson-Tsavoussis, Z., Brostean-Kaiser, J., Brusa, L., Burley, R. T., Butterfield, D., Campana, M. A., Caracas, I., Carloni, K., Carpio, J., Chattopadhyay, S., Chau, N., Chen, Z., Chirkin, D., Choi, S., Clark, B. A., Coleman, A., Coleman, P., Collin, G. H., Connolly, A., Conrad, J. M., Corley, R., Cowen, D. F., De Clercq, C., DeLaunay, J. J., Delgado, D., Deng, S., Desai, A., Desiati, P., de Vries, K. D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J. C., Dierichs, P., Dittmer, M., Domi, A., Draper, L., Dujmovic, H., Durnford, D., Dutta, K., DuVernois, M. A., Ehrhardt, T., Eidenschink, L., Eimer, A., Eller, P., Ellinger, E., Mentawi, S. El, Elsässer, D., Engel, R., Erpenbeck, H., Esmail, W., Evans, J., Evenson, P. A., Fan, K. L., Fang, K., Farrag, K., Fazely, A. R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Fukami, S., Fürst, P., Gallagher, J., Ganster, E., Garcia, A., Garcia, M., Garg, G., Genton, E., Gerhardt, L., Ghadimi, A., Girard-Carillo, C., Glaser, C., Glüsenkamp, T., Gonzalez, J. G., Goswami, S., Granados, A., Grant, D., Gray, S. J., Griffin, S., Griswold, S., Groth, K. M., Guevel, D., Günther, C., Gutjahr, P., Ha, C., Haack, C., Hallgren, A., Halve, L., Halzen, F., Hamacher, L., Hamdaoui, H., Minh, M. Ha, Handt, M., Hanson, K., Hardin, J., Harnisch, A. A., Hatch, P., Haungs, A., Häußler, J., Helbing, K., Hellrung, J., Hermannsgabner, J., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G. C., Hmaid, R., Hoffman, K. D., Hori, S., Hoshina, K., Hostert, M., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., Ishihara, A., Iwakiri, W., Jacquart, M., Jain, S., Janik, O., Jansson, M., Jeong, M., Jin, M., Jones, B. J. P., Kamp, N., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katil, A., Katz, U., Kauer, M., Kelley, J. L., Khanal, M., Zathul, A. Khatee, Kheirandish, A., Kiryluk, J., Klein, S. R., Kobayashi, Y., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D. J., Koundal, P., Kowalski, M., Kozynets, T., Krieger, N., Krishnamoorthi, J., Krishnan, T., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Gualda, C. Lagunas, Lamoureux, M., Larson, M. J., Lauber, F., Lazar, J. P., DeHolton, K. Leonard, Leszczyńska, A., Liao, J., Lincetto, M., Liu, Y. T., Liubarska, M., Love, C., Lu, L., Lucarelli, F., Luszczak, W., Lyu, Y., Madsen, J., Magnus, E., Mahn, K. B. M., Makino, Y., Manao, E., Mancina, S., Mand, A., Sainte, W. Marie, Mariş, I. C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McNally, F., Mead, J. V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Mitchell, J., Montaruli, T., Moore, R. W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nakos, M., Naumann, U., Necker, J., Negi, A., Neste, L., Neumann, M., Niederhausen, H., Nisa, M. U., Noda, K., Noell, A., Novikov, A., Pollmann, A. Obertacke, O'Dell, V., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Palusova, V., Pandya, H., Park, N., Parker, G. K., Parrish, V., Paudel, E. N., Paul, L., Heros, C. Pérez de los, Pernice, T., Peterson, J., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Rodriguez, M. Prado, Pries, B., Procter-Murphy, R., Przybylski, G. T., Pyras, L., Raab, C., Rack-Helleis, J., Rad, N., Ravn, M., Rawlins, K., Rechav, Z., Rehman, A., Resconi, E., Reusch, S., Rhode, W., Riedel, B., Rifaie, A., Roberts, E. J., Robertson, S., Rodan, S., Rongen, M., Rosted, A., Rott, C., Ruhe, T., Ruohan, L., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaile, P., Schaufel, M., Schieler, H., Schindler, S., Schlickmann, L., Schlüter, B., Schlüter, F., Schmeisser, N., Schmidt, T., Schneider, J., Schröder, F. G., Schumacher, L., Schwirn, S., Sclafani, S., Seckel, D., Seen, L., Seikh, M., Seo, M., Seunarine, S., Myhr, P. A. Sevle, Shah, R., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G. M., Spiering, C., Stachurska, J., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G. W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W. G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Elorrieta, M. A. Unland, Upadhyay, A. K., Upshaw, K., Vaidyanathan, A., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Varsi, F., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Carrasco, S. Vergara, Verpoest, S., Veske, D., Vijai, A., Walck, C., Wang, A., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wen, A. Y., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C. H., Williams, D. R., Witthaus, L., Wolf, M., Wrede, G., Xu, X. W., Yanez, J. P., Yildizci, E., Yoshida, S., Young, R., Yu, F., Yu, S., Yuan, T., Zegarelli, A., Zhang, S., Zhang, Z., Zhelnin, P., Zilberman, P., Zimmerman, M., Drake, Pablo, Spira-Savett, Elizabeth, Lusen, Piatra, and Mori, Kaya
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
While the sources of the diffuse astrophysical neutrino flux detected by the IceCube Neutrino Observatory are still largely unknown, one of the promising methods used towards understanding this is investigating the potential temporal and spatial correlations between neutrino alerts and the electromagnetic radiation from blazars. We report on the multiwavelength target-of-opportunity observations of the blazar B3 2247+381, taken in response to an IceCube multiplet alert for a cluster of muon neutrino events compatible with the source location between May 20, 2022 and November 10, 2022. B3 2247+381 was not detected with VERITAS during this time period. The source was found to be in a low-flux state in the optical, ultraviolet and gamma-ray bands for the time interval corresponding to the neutrino event, but was detected in the hard X-ray band with NuSTAR during this period. We find the multiwavelength spectral energy distribution is well described using a simple one-zone leptonic synchrotron self-Compton radiation model. Moreover, assuming the neutrinos originate from hadronic processes within the jet, the neutrino flux would be accompanied by a photon flux from the cascade emission, and the integrated photon flux required in such a case would significantly exceed the total multiwavelength fluxes and the VERITAS upper limits presented here. The lack of flaring activity observed with VERITAS, combined with the low multiwavelength flux levels, and given the significance of the neutrino excess is at 3$\sigma$ level (uncorrected for trials), makes B3 2247+381 an unlikely source of the IceCube multiplet. We conclude that the neutrino excess is likely a background fluctuation., Comment: 26 pages, 5 figures. Accepted for publication in the Astrophysical Journal (ApJ)
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- 2025
18. Developing multilingual speech synthesis system for Ojibwe, Mi'kmaq, and Maliseet
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Wang, Shenran, Yang, Changbing, Parkhill, Mike, Quinn, Chad, Hammerly, Christopher, and Zhu, Jian
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence ,Computer Science - Machine Learning ,Computer Science - Sound ,Electrical Engineering and Systems Science - Audio and Speech Processing - Abstract
We present lightweight flow matching multilingual text-to-speech (TTS) systems for Ojibwe, Mi'kmaq, and Maliseet, three Indigenous languages in North America. Our results show that training a multilingual TTS model on three typologically similar languages can improve the performance over monolingual models, especially when data are scarce. Attention-free architectures are highly competitive with self-attention architecture with higher memory efficiency. Our research not only advances technical development for the revitalization of low-resource languages but also highlights the cultural gap in human evaluation protocols, calling for a more community-centered approach to human evaluation.
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- 2025
19. End-to-End Imitation Learning for Optimal Asteroid Proximity Operations
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Quinn, Patrick, Nehma, George, and Tiwari, Madhur
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Computer Science - Robotics ,Computer Science - Machine Learning ,I.2.9 - Abstract
Controlling spacecraft near asteroids in deep space comes with many challenges. The delays involved necessitate heavy usage of limited onboard computation resources while fuel efficiency remains a priority to support the long loiter times needed for gathering data. Additionally, the difficulty of state determination due to the lack of traditional reference systems requires a guidance, navigation, and control (GNC) pipeline that ideally is both computationally and fuel-efficient, and that incorporates a robust state determination system. In this paper, we propose an end-to-end algorithm utilizing neural networks to generate near-optimal control commands from raw sensor data, as well as a hybrid model predictive control (MPC) guided imitation learning controller delivering improvements in computational efficiency over a traditional MPC controller., Comment: 7 pages, 8 figures. Submitted to the 2025 IEEE Aerospace Conference
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- 2025
20. A 16 Myr super-Neptune in Upper-Centaurus Lupus and a preliminary survey of transiting planets in Sco-Cen with TESS
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Vach, Sydney, Zhou, George, Mann, Andrew W., Barber, Madyson G., Fairnington, Tyler R., Huang, Chelsea X., Rogers, James G., Bouma, Luke G., Krüger, Joachim, Wright, Duncan, Niblett, Annabelle E., Nelson, Jack M., Quinn, Samuel N., Latham, David W., Bieryla, Allyson, Collins, Karen A., Kunimoto, Michelle, Watkins, Cristilyn N., Schwarz, Richard P., Collins, Kevin I., Sefako, Ramotholo, Horne, Keith, Howell, Steve B., Clark, Catherine A., Littlefield, Colin, Christiansen, Jessie L., Essack, Zahra, and Winn, Joshua N.
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Astrophysics - Earth and Planetary Astrophysics - Abstract
Measuring the properties of planets younger than about 50 Myr helps to test different planetary formation and evolution models. NASA's Transiting Exoplanet Survey Satellite (TESS) has observed nearly the entire sky, including a wide range of star-forming regions and young stellar clusters, expanding our census of the newborn planet population. In this work, we present the discovery of the TIC 88785435 planetary system located in the Upper-Centaurus Lupus (UCL) region of the Scorpius-Centaurus OB association (Sco-Cen) and a preliminary survey of the planet population within Sco-Cen. TIC 88785435 is a pre-main sequence, K7V dwarf ($M_\star = 0.72M_\odot$, $R_\star = 0.91R_\odot$, $T_\mathrm{eff}$ = 3998K, V = 11.7 mag) located within the bounds of UCL. We investigate the distribution of rotation periods measured from the TESS long-cadence data and the Halpha and Li abundances from the spectra of TIC 88785435. TESS long-candence data reveal that TIC 88785435 hosts a transiting super-Neptune ($R_b = 5.03R_\oplus$, P = 10.51 days), TIC 88785435 b. Ground-based follow-up validates the planetary nature of TIC 88785435 b. Using the TESS data, we perform a preliminary survey to investigate how TIC 88785435 b compares to the population of newly born planets located within Sco-Cen., Comment: 15 pages, 9 Figures, submitted to AJ
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- 2025
21. Million Points of Light (MPoL): a PyTorch library for radio interferometric imaging and inference
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Czekala, Ian, Jennings, Jeff, Zawadzki, Brianna, Nizam, Kadri, Loomis, Ryan, Delamer, Megan, de Soto, Kaylee, Frazier, Robert, Grzybowski, Hannah, Huang, Jane, Ogborn, Mary, and Quinn, Tyler
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Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Earth and Planetary Astrophysics - Abstract
Astronomical radio interferometers achieve exquisite angular resolution by cross-correlating signal from a cosmic source simultaneously observed by distant pairs of radio telescopes to produce a Fourier-type measurement called a visibility. Million Points of Light (MPoL) is a Python library supporting feed-forward modeling of interferometric visibility datasets for synthesis imaging and parametric Bayesian inference, built using the autodifferentiable machine learning framework PyTorch. Neural network components provide a rich set of modular and composable building blocks that can be used to express the physical relationships between latent model parameters and observed data following the radio interferometric measurement equation. Industry-grade optimizers make it straightforward to simultaneously solve for the synthesized image and calibration parameters using stochastic gradient descent., Comment: Submitted to JOSS. 1559 words, 1 figure
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- 2025
22. Structure and Dynamics of the Young Massive Star Cluster Westerlund 1
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Wei, Lingfeng, Lu, Jessica R., Boyle, Peter C., Hosek Jr., Matthew W., Konopacky, Quinn M., Spencer, Richard G., Kim, Dongwon, Rui, Nicholas Z., Service, Max, Huang, D. B., and Anderson, Jay
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Astrophysics - Astrophysics of Galaxies ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present a structural analysis of the young massive star cluster Westerlund 1 (Wd 1). With multi-epoch Hubble Space Telescope (HST) observations, we measure the proper motions of $10346$ stars and determine their kinematic memberships by fitting a Gaussian mixture model to their proper motions. After correcting for extinction and completeness, we model the stellar density distribution and confirm the presence of an elongation with an eccentricity of $0.71$. The eccentricity decreases slightly with increasing mass. We fit the radial profile with the Elson, Fall, and Freeman model, observing a decrease in the core radius with increasing mass, indicative of weak but detectable mass segregation. This finding is further supported by a measured mass segregation ratio of $\Lambda_\mathrm{\rm MSR}=1.11\pm0.11$, only above $1$ by $1\sigma$, and slightly shorter minimum spanning tree length for higher mass bins. The cluster has a 1D velocity dispersion of $3.42 \pm 0.10~\mathrm{km}\,\mathrm{s}^{-1}$, suggesting it is subvirial. The subvirial state implies either exceptionally high star formation efficiency or inefficient stellar feedback caused by local gas expulsion before stars reach the cluster. The crossing time is $0.30$ Myr and the relaxation time is $0.26$ Gyr. Given the age of Wd 1 of $10.7$ Myr, we expect evident mass segregation for stars more massive than $10~M_\odot$, which accounts for the minor mass segregation found in the mass range of $1.00\unicode{x2013}12.14~M_\odot$ in this work. This suggests the overall mass segregation in Wd 1 is not primordial., Comment: 26 pages, 22 figures, 6 tables
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- 2025
23. CARING-AI: Towards Authoring Context-aware Augmented Reality INstruction through Generative Artificial Intelligence
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Shi, Jingyu, Jain, Rahul, Chi, Seungguen, Doh, Hyungjun, Chi, Hyunggun, Quinn, Alexander J., and Ramani, Karthik
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Computer Science - Human-Computer Interaction - Abstract
Context-aware AR instruction enables adaptive and in-situ learning experiences. However, hardware limitations and expertise requirements constrain the creation of such instructions. With recent developments in Generative Artificial Intelligence (Gen-AI), current research tries to tackle these constraints by deploying AI-generated content (AIGC) in AR applications. However, our preliminary study with six AR practitioners revealed that the current AIGC lacks contextual information to adapt to varying application scenarios and is therefore limited in authoring. To utilize the strong generative power of GenAI to ease the authoring of AR instruction while capturing the context, we developed CARING-AI, an AR system to author context-aware humanoid-avatar-based instructions with GenAI. By navigating in the environment, users naturally provide contextual information to generate humanoid-avatar animation as AR instructions that blend in the context spatially and temporally. We showcased three application scenarios of CARING-AI: Asynchronous Instructions, Remote Instructions, and Ad Hoc Instructions based on a design space of AIGC in AR Instructions. With two user studies (N=12), we assessed the system usability of CARING-AI and demonstrated the easiness and effectiveness of authoring with Gen-AI.
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- 2025
24. A MARVEL-ous study of how well galaxy shapes reflect Dark Matter halo shapes in Cold Dark Matter Simulations
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Keith, Blake, Munshi, Ferah, Brooks, Alyson M., Van Nest, Jordan, Engelhardt, Anna, Cruz, Akaxia, Keller, Ben, Quinn, Thomas, and Wadsley, James
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Astrophysics - Astrophysics of Galaxies - Abstract
We present a 3D shape analysis of both dark matter (DM) and stellar matter (SM) in simulated dwarf galaxies to determine whether stellar shape traces DM shape. Using 80 central and satellite galaxies from three simulation suites (Marvelous Massive Dwarfs, Marvelous Dwarfs, and DC Justice League) spanning stellar masses of $10^6$--$10^{10}$ M$_\odot$, we measure 3D shapes through the moment of inertia tensor at two times the effective radius to derive axis ratios ($C/A$, $B/A$) and triaxiality. We find that stellar shape does indeed follow DM halo shape for our dwarf galaxies. However, the presence of a stellar disk in more massive dwarfs (M$_* \gtrsim 10^{7.5}$ M$_\odot$) pulls the distribution of stellar $C/A$ ratios to lower values, while in lower mass galaxies the gravitational potential remains predominantly shaped by DM. Similarly, stellar triaxiality generally tracks dark matter halo triaxiality, with this relationship being particularly strong for non-disky galaxies though weaker in disky systems. This correlation is reinforced by strong alignment between SM and DM axes, particularly in disk galaxies. Further, we find no detectable difference in either SM or DM shape comparing two different SNe feedback implementations, demonstrating that shape measurements may be robust to different implementations of baryonic feedback in dwarf galaxies. We also observe that a dwarf galaxy's shape is largely unperturbed by recent mergers (with merger ratios $>4$). This comprehensive study demonstrates that stellar shape measurements can serve as a reliable tool for inferring DM shapes in dwarf galaxies., Comment: 22 pages, 14 figures, Submitted to ApJ
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- 2025
25. Pervasiveness of $\mathcal{L}^r(E,F)$ in $\mathcal{L}^r(E,F^{\delta})$
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Starkey, Quinn Kiervin and Xanthos, Foivos
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Mathematics - Functional Analysis ,46A40, 46B42, 47B65 - Abstract
Let $E, F$ be Archimedean Riesz spaces, and let $F^{\delta}$ denote an order completion of $F$. In this note, we provide necessary conditions under which the space of regular operators $\mathcal{L}^r(E, F)$ is pervasive in $\mathcal{L}^r(E, F^{\delta})$. Pervasiveness of $\mathcal{L}^r(E, F)$ in $\mathcal{L}^r(E, F^{\delta})$ implies that the Riesz completion of $ \mathcal{L}^r(E, F)$ can be realized as a Riesz subspace of $ \mathcal{L}^r(E, F^{\delta}$. It also ensures that the regular part of the space of order continuous operators $\mathcal{L}^{oc}(E, F)$ forms a band of $\mathcal{L}^r(E, F)$. Furthermore, the positive part $T^+$ of any operator $T \in \mathcal{L}^r(E, F)$, provided it exists, is given by the Riesz-Kantorovich formula. The results apply in particular to cases where $E = \ell_0^{\infty}$, $E = c$, or $F$ is atomic, and they provide solutions to some problems posed in [3] and [16].
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- 2025
26. The NCORES Program: Precise planetary masses, null results, and insight into the planet mass distribution near the radius gap
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Armstrong, David J., Osborn, Ares, Burn, Remo, Venturini, Julia, Adibekyan, Vardan, Bonfanti, Andrea, Burt, Jennifer A., Collins, Karen A., Mena, Elisa Delgado, Hadjigeorghiou, Andreas, Howell, Steve, Quinn, Sam, Sousa, Sergio G., Keniger, Marcelo Aron F., Barrado, David, Barros, Susana C. C., Bayliss, Daniel, Bouchy, François, Castro-González, Amadeo, Collins, Kevin I., Conti, Denis M., Crossfield, Ian M., Diaz, Rodrigo, Dumusque, Xavier, Feng, Fabo, Lester, Kathryn V., Box, Jorge Lillo, Matson, Rachel A., Matthews, Elisabeth C., Mordasini, Christoph, Murgas, Felipe, Osborn, Hugh P., Palle, Enric, Santos, Nuno, Schwarz, Richard P., Silva, Tomás Azevedo, Stassun, Keivan, Strøm, Paul, Tan, Thiam-Guan, Teske, Johanna, Wang, Gavin, and Wheatley, Peter J.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
NCORES was a large observing program on the ESO HARPS spectrograph, dedicated to measuring the masses of Neptune-like and smaller transiting planets discovered by the TESS satellite using the radial velocity technique. This paper presents an overview of the programme, its scientific goals and published results, covering 35 planets in 18 planetary systems. We present spectrally derived stellar characterisation and mass constraints for five additional TOIs where radial velocity observations found only marginally significant signals (TOI-510.01, $M_p=1.08^{+0.58}_{-0.55}M_\oplus$), or found no signal (TOIs 271.01, 641.01, 697.01 and 745.01). A newly detected non-transiting radial velocity candidate is presented orbiting TOI-510 on a 10.0d orbit, with a minimum mass of $4.82^{+1.29}_{-1.26}M_\oplus$, although uncertainties on the system architecture and true orbital period remain. Combining the NCORES sample with archival known planets we investigate the distribution of planet masses and compositions around and below the radius gap, finding that the population of planets below the gap is consistent with a rocky composition and ranges up to a sharp cut-off at $10M_\oplus$. We compare the observed distribution to models of pebble- and planetesimal-driven formation and evolution, finding good broad agreement with both models while highlighting interesting areas of potential discrepancy. Increased numbers of precisely measured planet masses in this parameter space are required to distinguish between pebble and planetesimal accretion., Comment: Accepted to MNRAS. Minor updates to text, references, affiliations
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- 2025
27. HD 206893 B at High Spectral Resolution with the Keck Planet Imager and Characterizer (KPIC)
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Sappey, Ben, Konopacky, Quinn, O, Clarissa R. Do, Barman, Travis, Ruffio, Jean-Baptiste, Wang, Jason, Theissen, Christopher A., Finnerty, Luke, Xuan, Jerry, Hortsman, Katelyn, Mawet, Dimitri, Zhang, Yapeng, Inglis, Julie, Wallack, Nicole L., Sanghi, Aniket, Baker, Ashley, Bartos, Randall, Blake, Geoffrey A., Bond, Charlotte Z., Calvin, Benjamin, Cetre, Sylvain, Delorme, Jacques-Robert, Doppmann, Greg, Echeverri, Daniel, Fitzgerald, Michael P., Hsu, Chih-Chun, Jovanovic, Nemanja, Liberman, Joshua, Lopez, Ronald A., Martin, Emily C., Morris, Evan, Pezzato-Rovner, Jacklyn, Phillips, Caprice L., Ruane, Garreth, Schofield, Tobias, Skemer, Andrew, Venenciano, Taylor, Wallace, J. Kent, Wang, Ji, Wizinowich, Peter, and Xin, Yinzi
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present an atmospheric characterization and orbital analysis of HD 206893 B, an exceptionally red, L/T-transition substellar companion in a multiplanetary system, via Keck Planet Imager and Characterizer (KPIC) high-resolution (R $\sim$ 35,000) K-band spectroscopy. Using PHOENIX atmospheric models in a forward-model framework that fits the spectrum of the companion and diffracted starlight simultaneously, we detect HD 206893 B at $>8\sigma$ significance via cross-correlation in two epochs. We find an effective temperature for the companion of $1634^{+72}_{-38}$ K and a log(g) of $4.55^{+0.17}_{-0.22}$. Only accounting for statistical uncertainties, we measure the carbon-oxygen ratio (C/O) of this companion to be $0.57 \pm 0.02$, or near-solar while assuming solar metallicity. The C/O ratio we measure fits the tentative trend of $>4 M_{Jup}$ companions having near-solar C/O ratios while less massive companions have greater-than-solar C/O ratios. Using substellar evolution models, we find an age of $112^{+36}_{-22}$ Myr, a mass of $22.7^{+2.5}_{-1.7} M_{Jup}$, and a radius of $1.11 \pm 0.03 R_{Jup}$ for this companion. We also use KPIC radial velocity data to fit the orbit of HD 206893 B and analyze the orbital stability of this system. We find that the orbital stability is relatively independent of the mass of HD 206893 B, and favors an orbital configuration where B and its interior planetary companion, HD 206893 c, are co-planar. The measured C/O ratio coupled with the current architecture of the system cannot rule out a core accretion scenario, nor a disk fragmentation scenario regarding the formation pathway of HD 206893 B., Comment: 37 pages, 23 figures
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- 2025
28. The Impact of Helium Exposure on the PMTs of the SuperNEMO Experiment
- Author
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SuperNEMO Collaboration, Aguerre, X., Barabash, A. S., Basharina-Freshville, A., Bongrand, M., Bourgeois, Ch., Breton, D., Breier, R., Busto, J., Cerna, C., Ceschia, M., Chauveau, E., Chopra, A., Dawson, L., Duchesneau, D., Evans, J. J., Filosofov, D., Garrido, X., Girard-Carillo, C., Granjon, M., Hoballah, M., Hodák, R., Horner, G., Hussain, M. H., Islam, A., Jérémie, A., Jullian, S., Kaizer, J., Klimenko, A., Kochetov, O., Koňařík, F., Konovalov, S. I., Křižák, T., Kovalenko, S., Lahaie, A., Lang, K., Lemière, Y., Li, P., Maalmi, J., Macko, M., Mamedov, F., Marquet, C., Mauger, F., Mendl, A., Morgan, B., Nemchenok, I., Nomachi, M., Palušová, V., Patrick, C., Pavicic, T., Perrot, F., Petro, M., Piquemal, F., Povinec, P., Pratt, S., Proga, M., Quinn, W. S., Ramachers, Y. A., Riddle, C. L., Rukhadze, N., Saakyan, R., Salazar, R., Sedgbeer, J., Shitov, Yu., Simard, L., Šimkovic, F., Smolnikov, A., Söldner-Rembold, S., Štekl, I., Suhonen, J., Tedjditi, H., Thomas, J., Timkin, V., Tretyak, V. I., Tretyak, Vl. I., Turnbull, G., Umatov, V. I., Vereshchaka, Y., and Waters, D.
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Physics - Instrumentation and Detectors ,Nuclear Experiment - Abstract
The performance of Hamamatsu 8" photomultiplier tubes (PMTs) of the type used in the SuperNEMO neutrinoless double-beta decay experiment (R5912-MOD), is investigated as a function of exposure to helium (He) gas. Two PMTs were monitored for over a year, one exposed to varying concentrations of He, and the other kept in standard atmospheric conditions as a control. Both PMTs were exposed to light signals generated by a Bi-207 radioactive source that provided consistent large input PMT signals similar to those that are typical of the SuperNEMO experiment. The energy resolution of PMT signals corresponding to 1 MeV energy scale determined from the Bi-207 decay spectrum, shows a negligible degradation with He exposure; however the rate of after-pulsing shows a clear increase with He exposure, which is modelled and compared to diffusion theory. A method for reconstructing the partial pressure of He within the PMT and a method for determining the He breakdown point, are introduced. The implications for long-term SuperNEMO operations are briefly discussed.
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- 2025
29. Sunny.jl: A Julia Package for Spin Dynamics
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Dahlbom, David, Zhang, Hao, Miles, Cole, Quinn, Sam, Niraula, Alin, Thipe, Bhushan, Wilson, Matthew, Matin, Sakib, Mankad, Het, Hahn, Steven, Pajerowski, Daniel, Johnston, Steve, Wang, Zhentao, Lane, Harry, Li, Ying Wai, Bai, Xiaojian, Mourigal, Martin, Batista, Cristian D., and Barros, Kipton
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Quantum Physics ,Condensed Matter - Strongly Correlated Electrons ,Physics - Computational Physics - Abstract
Sunny is a Julia package designed to serve the needs of the quantum magnetism community. It supports the specification of a very broad class of spin models and a diverse suite of numerical solvers. These include powerful methods for simulating spin dynamics both in and out of equilibrium. Uniquely, it features a broad generalization of classical and semiclassical approaches to SU(N) coherent states, which is useful for studying systems exhibiting strong spin-orbit coupling or local entanglement effects. Sunny also offers a well-developed framework for calculating the dynamical spin structure factor, enabling direct comparison with scattering experiments. Ease of use is a priority, with tools for symmetry-guided modeling and interactive visualization.
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- 2025
30. An in-depth study of Gamma rays from the Starburst Galaxy M 82 with VERITAS
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Acharyya, Atreya, Adams, Colin B., Bangale, Priyadarshini, Bartkoske, Joshua T., Benbow, Wystan, Chen, Yu, Christiansen, Jodi L., Chromey, Alisha J., Duerr, Anne, Errando, Manel, Godoy, Miguel E., Falcone, Abe, Feldman, Sydney, Feng, Qi, Foote, Juniper, Fortson, Lucy, Furniss, Amy, Hanlon, William, Hanna, David, Hervet, Olivier, Hinrichs, Claire E., Holder, Jamie, Humensky, Thomas B., Jin, Weidong, Johnson, Madalyn N., Kaaret, Philip, Kertzman, Mary, Kherlakian, Maria, Kieda, David, Kleiner, Tobias K., Korzoun, Nikolas, Krennrich, Frank, Kumar, Sajan, Lang, Mark J., Lundy, Matthew, Maier, Gernot, Millard, Matthew J., Mooney, Connor L., Moriarty, Patrick, Mukherjee, Reshmi, Ning, Wenmeng, Brien, Stephan Ó, Ong, Rene A., Pohl, Martin, Pueschel, Elisa, Quinn, John, Rabinowitz, Pazit L., Ragan, Kenneth J., Reynolds, Paul T., Ribeiro, Deivid, Roache, Emmet, Sadeh, Iftach, Saha, Lab, Santander, Marcos, Sembroski, Glenn H., Shang, Ruo, Splettstoesser, Megan, Talluri, Anjana K., Tucci, James V., Vassiliev, Vladimir V., Williams, David A., Wong, Samantha L., and Woo, Jooyun
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Assuming Galactic cosmic rays originate in supernovae and the winds of massive stars, starburst galaxies should produce very-high-energy (VHE; E$>$100 GeV) gamma-ray emission via the interaction of their copious quantities of cosmic rays with the large reservoirs of dense gas within the galaxies. Such VHE emission was detected by VERITAS from the starburst galaxy M 82 in 2008-09. An extensive, multi-year campaign followed these initial observations, yielding a total of 254 h of good quality VERITAS data on M 82. Leveraging modern analysis techniques and the larger exposure, these VERITAS data show a more statistically significant VHE signal ($\sim$6.5 standard deviations ($\sigma$)). The corresponding photon spectrum is well fit by a power law ($\Gamma = 2.3 \pm 0.3_{stat} \pm0.2_{sys}$) and the observed integral flux is F($>$450 GeV) = $(3.2 \pm0.6_{stat} \pm 0.6_{sys}) \times 10^{-13}~\mathrm{cm^{-2}~s}^{-1}$, or $\sim$0.4\% of the Crab Nebula flux above the same energy threshold. The improved VERITAS measurements, when combined with various multi-wavelength data, enable modeling of the underlying emission and transport processes. A purely leptonic scenario is found to be a poor representation of the gamma-ray spectral energy distribution (SED). A lepto-hadronic scenario with cosmic rays following a power-law spectrum in momentum (index $s\simeq 2.25$), and with significant bremsstrahlung below $1$~GeV, provides a good match to the observed SED. The synchrotron emission from the secondary electrons indicates that efficient non-radiative losses of cosmic-ray electrons may be related to advective escape from the starburst core., Comment: 15 pages, 7 figures; Accepted for the publication in The Astrophysical Journal (ApJ)
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- 2025
31. 11 New Transiting Brown Dwarfs and Very Low Mass Stars from TESS
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Vowell, Noah, Rodriguez, Joseph E., Latham, David W., Quinn, Samuel N., Schulte, Jack, Eastman, Jason D., Bieryla, Allyson, Barkaoui, Khalid, Ciardi, David R., Collins, Karen A., Girardin, Eric, Heldridge, Ellie, Kotten, Brooke, Mancini, Luigi, Murgas, Felipe, Narita, Norio, Radford, D. J., Relles, Howard M., Shporer, Avi, Soares-Furtado, Melinda, Strakhov, Ivan A., Ziegler, Carl, Briceño, César, Calkins, Michael L., Clark, Catherine A., Collins, Kevin I., Esquerdo, Gilbert A., Fajardo-Acosta, Sergio B., Fukui, Akihiko, Watkins, Cristilyn N., He, Ruixuan, Horne, Keith, Jenkins, Jon M., Mann, Andrew W., Naponiello, Luca, Palle, Enric, Schwarz, Richard P., Seager, S., Southworth, John, Srdoc, Gregor, Swift, Jonathan J., and Winn, Joshua N.
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Astrophysics - Earth and Planetary Astrophysics ,Astrophysics - Solar and Stellar Astrophysics - Abstract
We present the discovery of 11 new transiting brown dwarfs and low-mass M-dwarfs from NASA's TESS mission: TOI-2844, TOI-3122, TOI-3577, TOI-3755, TOI-4462, TOI-4635, TOI-4737, TOI-4759, TOI-5240, TOI-5467, and TOI-5882. They consist of 5 brown dwarf companions and 6 very low mass stellar companions ranging in mass from $25 M_{\rm J}$ to $128 M_{\rm J}$. We used a combination of photometric time-series, spectroscopic, and high resolution imaging follow-up as a part of the TESS Follow-up Observing Program (TFOP) in order to characterize each system. With over 50 transiting brown dwarfs confirmed, we now have a large enough sample to directly test different formation and evolutionary scenarios. We provide a renewed perspective on the transiting brown dwarf desert and its role in differentiating between planetary and stellar formation mechanisms. Our analysis of the eccentricity distribution for the transiting brown dwarf sample does not support previous claims of a transition between planetary and stellar formation at $\sim42$ $M_{\rm J}$. We also contribute a first look into the metallicity distribution of transiting companions in the range $7 - 150$ $M_{\rm J}$, showing that this too does not support a $\sim42$ $M_{\rm J}$ transition. Finally, we also detect a significant lithium absorption feature in one of the brown dwarf hosts (TOI-5882) but determine that the host star is likely old based on rotation, kinematic, and photometric measurements. We therefore claim that TOI-5882 may be a candidate for planetary engulfment., Comment: Submitted, 32 pages, 16 figures
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- 2025
32. Symbol Resolution MatRs: Make it Fast and Observable with Stable Linking
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Zakaria, Farid, Quinn, Andrew, and Scogland, Thomas R. W.
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Computer Science - Operating Systems ,Computer Science - Software Engineering - Abstract
Dynamic linking is the standard mechanism for using external dependencies since it enables code reuse, streamlines software updates, and reduces disk/network use. Dynamic linking waits until runtime to calculate an application's relocation mapping, i.e., the mapping between each externally referenced symbol in the application to the dependency that provides the symbol. Unfortunately, it comes with two downsides. First, dynamic linking limits the performance of current systems since it can take seconds to calculate a relocation mapping for a large program. Second, dynamic linking limits the dependency management of applications since it prevents a developer from accurately observing a relocation mapping except at runtime. This paper makes the key insight that the benefits conventionally attributed to dynamic linking: code reuse, streamlined software updates, and reduced disk/network use are actually benefits of shared libraries. Thus, we present stable linking, a new mechanism for using dependencies that uses shared libraries to retain their benefits but eliminates the downsides of dynamic linking. Stable linking separates a system's state into management times; when the system can be modified, and epochs when it cannot. Stable linking calculates each application's relocation mapping at the beginning of each epoch, allows developers to inspect the relocation mapping during the epoch, and reuses the mapping for subsequent executions in the epoch. We design and build MatR, the first stable linker. We use MatR in three workloads and show that it improves upon dynamic linking performance by a factor of 2.19 on average. Additionally, we use the system in three vignettes, or case-studies, that illustrate the system's improvements to dependency management., Comment: 11 pages
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- 2025
33. Geodesic Variational Bayes for Multiway Covariances
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Simonis, Quinn and Wells, Martin T.
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Statistics - Computation - Abstract
This article explores the optimization of variational approximations for posterior covariances of Gaussian multiway arrays. To achieve this, we establish a natural differential geometric optimization framework on the space using the pullback of the affine-invariant metric. In the case of a truly separable covariance, we demonstrate a joint approximation in the multiway space outperforms a mean-field approximation in optimization efficiency and provides a superior approximation to an unstructured Inverse-Wishart posterior under the average Mahalanobis distance of the data while maintaining a multiway interpretation. We moreover establish efficient expressions for the Euclidean and Riemannian gradients in both cases of the joint and mean-field approximation. We end with an analysis of commodity trade data., Comment: 40 pages, 4 figures, 1 table
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- 2025
34. Separable Geodesic Lagrangian Monte Carlo for Inference in 2-Way Covariance Models
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Simonis, Quinn and Wells, Martin T.
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Statistics - Computation - Abstract
Matrix normal models have an associated 4-tensor for their covariance representation. The covariance array associated with a matrix normal model is naturally represented as a Kronecker-product structured covariance associated with the vector normal, also known as separable covariance matrices. Separable covariance matrices have been studied extensively in the context of multiway data, but little work has been done within the scope of MCMC beyond Gibbs sampling. This paper aims to fill this gap by considering the pullback geometry induced from the Kronecker structure of the parameter space to develop a geodesic Hamiltonian Monte Carlo sampler., Comment: 67 pages, 24 figures, 1 table
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- 2025
35. Deep Photometric Observations of Ultra-Faint Milky Way Satellites Centaurus I and Eridanus IV
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Casey, Quinn O., Mutlu-Pakdil, Burçin, Sand, David J., Pace, Andrew B., Crnojevic, Denija, Doliva-Dolinsky, Amandine, Cerny, William, Heiger, Mairead E., Riley, Alex H., Ji, Alexander P., Limberg, Guilherme, Marin, Laurella, Martínez-Vázquez, Clara E., Medina, Gustavo E., Li, Ting S., Campana, Sasha N., Chaturvedi, Astha, Sakowska, Joanna D., Zenteno, Alfredo, Carballo-Bello, Julio A., Navabi, Mahdieh, and Bom, Clecio R.
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Astrophysics - Astrophysics of Galaxies - Abstract
We present deep Magellan$+$Megacam imaging of Centaurus I (Cen I) and Eridanus IV (Eri IV), two recently discovered Milky Way ultra-faint satellites. Our data reach $\sim2-3$ magnitudes deeper than the discovery data from the DECam Local Volume Exploration (DELVE) Survey. We use these data to constrain their distances, structural properties (e.g., half-light radii, ellipticity, and position angle), and luminosities. We investigate whether these systems show signs of tidal disturbance, and identify new potential member stars using Gaia EDR3. Our deep color-magnitude diagrams show that Cen I and Eri IV are consistent with an old ($\tau\sim 13.0$ Gyr) and metal-poor ($\text{[Fe/H]}\le-2.2$) stellar population. We find Cen I to have a half-light radius of $r_{h}=2.60\pm0.30'$ ($90.6\pm11$ pc), an ellipticity of $\epsilon=0.36\pm0.05$, a distance of $D=119.8\pm4.1$ kpc ($m-M=20.39\pm0.08$ mag), and an absolute magnitude of $M_{V}=-5.39\pm0.19$. Similarly, Eri IV has $r_{h}=3.24\pm0.48'$ ($65.9\pm10$ pc), $\epsilon=0.26\pm0.09$, $D=69.9\pm3.6$ kpc ($m-M=19.22\pm0.11$ mag), and $M_{V}=-3.55\pm0.24$. These systems occupy a space on the size-luminosity plane consistent with other known Milky Way dwarf galaxies which supports the findings from our previous spectroscopic follow-up. Cen I has a well-defined morphology which lacks any clear evidence of tidal disruption, whereas Eri IV hosts a significant extended feature with multiple possible interpretations., Comment: 14 pages, 3 figures. Submitted to ApJ, comments are welcome!
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- 2025
36. Roadmap on Atomic-scale Semiconductor Devices
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Schofield, Steven R., Fisher, Andrew J., Ginossar, Eran, Lyding, Joseph W., Silver, Richard, Fei, Fan, Namboodiri, Pradeep, Wyrick, Jonathan, Masteghin, M. G., Cox, D. C., Murdin, B. N., Clowes, S. K, Keizer, Joris G., Simmons, Michelle Y., Stemp, Holly G., Morello, Andrea, Voisin, Benoit, Rogge, Sven, Wolkow, Robert A., Livadaru, Lucian, Pitters, Jason, Stock, Taylor J. Z., Curson, Neil J., Butera, Robert E., Pavlova, Tatiana V., Jakob, A. M., Spemann, D., Räcke, P., Schmidt-Kaler, F., Jamieson, D. N., Pratiush, Utkarsh, Duscher, Gerd, Kalinin, Sergei V., Kazazis, Dimitrios, Constantinou, Procopios, Aeppli, Gabriel, Ekinci, Yasin, Owen, James H. G., Fowler, Emma, Moheimani, S. O. Reza, Randall, John N., Misra, Shashank, Ivie, Jeffrey, Allemang, Christopher R., Anderson, Evan M., Bussmann, Ezra, Campbell, Quinn, Gao, Xujiao, Lu, Tzu-Ming, and Schmucker, Scott W.
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Quantum Physics ,Physics - Applied Physics - Abstract
Spin states in semiconductors provide exceptionally stable and noise-resistant environments for qubits, positioning them as optimal candidates for reliable quantum computing technologies. The proposal to use nuclear and electronic spins of donor atoms in silicon, introduced by Kane in 1998, sparked a new research field focused on the precise positioning of individual impurity atoms for quantum devices, utilising scanning tunnelling microscopy and ion implantation. This roadmap article reviews the advancements in the 25 years since Kane's proposal, the current challenges, and the future directions in atomic-scale semiconductor device fabrication and measurement. It covers the quest to create a silicon-based quantum computer and expands to include diverse material systems and fabrication techniques, highlighting the potential for a broad range of semiconductor quantum technological applications. Key developments include phosphorus in silicon devices such as single-atom transistors, arrayed few-donor devices, one- and two-qubit gates, three-dimensional architectures, and the development of a toolbox for future quantum integrated circuits. The roadmap also explores new impurity species like arsenic and antimony for enhanced scalability and higher-dimensional spin systems, new chemistry for dopant precursors and lithographic resists, and the potential for germanium-based devices. Emerging methods, such as photon-based lithography and electron beam manipulation, are discussed for their disruptive potential. This roadmap charts the path toward scalable quantum computing and advanced semiconductor quantum technologies, emphasising the critical intersections of experiment, technological development, and theory., Comment: 94 pages
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- 2025
37. Confirmation of four hot Jupiters detected by TESS using follow-up spectroscopy from MaHPS at Wendelstein together with NEID and TRES
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Ehrhardt, Juliana, Thomas, Luis, Kellermann, Hanna, Freitag, Christine, Grupp, Frank, Yee, Samuel W., Winn, Joshua N., Hartman, Joel D., Collins, Karen A., Watkins, Cristilyn N., Stassun, Keivan G., Benni, Paul, Bieryla, Allyson, Carden, Kylee, Checinski, Jacek, Cheryasov, Dmitry V., Diamond, Brendan, Dowling, Nicholas, Dressing, Courtney D., Esparza-Borges, Emma, Evans, Phil, Forés-Toribio, Raquel, Fukui, Akihiko, Giacalone, Steven, Girardin, Eric, Goeke, Robert F., Goessl, Claus, Hayashi, Yuya, Hopp, Ulrich, Jenkins, Jon M., Khan, Isa, Laloum, Didier, Lark, Adam, Latham, David W., de Leon, Jerome, Marchini, Alessandro, Massey, Bob, Munoz, Jose A., Murgas, Felipe, Narita, Norio, Palle, Enric, Papini, Riccardo, Parviainen, Hannu, Pippert, Jan-Niklas, Popowicz, Adam, Pritchard, Tyler, Quinn, Samuel N., Raetz, Manfred, Ries, Christoph, Riffeser, Arno, Savel, Arjun B., Seager, Sara, Schmidt, Michael, Striegel, Stephanie, Srdoc, Gregor, Stockdale, Chris, Verna, Gaia, Watanabe, David, Ziegler, Carl, and Zöller, Raphael
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Astrophysics - Earth and Planetary Astrophysics - Abstract
We report the confirmation and characterization of four hot Jupiter-type exoplanets initially detected by TESS: TOI-1295 b, TOI-2580 b, TOI-6016 b, and TOI-6130 b. Using observations with the high-resolution echelle spectrograph MaHPS on the 2.1m telescope at Wendelstein Observatory, together with NEID at Kitt Peak National Observatory and TRES at the Fred Lawrence Whipple Observatory, we confirmed the planetary nature of these four planet candidates. We also performed precise mass measurements. All four planets are found to be hot Jupiters with orbital periods between 2.4 and 4.0 days. The sizes of these planets range from 1.29 to 1.64 Jupiter radii, while their masses range from 0.6 to 1.5 Jupiter masses. Additionally, we investigated whether there are signs of other planets in the systems but have found none. Lastly, we compared the radii of our four objects to the results of an empirical study of radius inflation and see that all four demonstrate a good fit with the current models. These four planets belong to the first array of planets confirmed with MaHPS data, supporting the ability of the spectrograph to detect planets around fainter stars as faint as V=12.
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- 2025
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38. TOI-5108 b and TOI 5786 b: Two transiting sub-Saturns detected and characterized with TESS, MaHPS and SOPHIE
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Thomas, Luis, Hébrard, Guillaume, Kellermann, Hanna, Korth, Judith, Heidari, Neda, Forveille, Thierry, Sousa, Sérgio G., Schöller, Laura, Riffeser, Arno, Gössl, Claus, Bell, Juan Serrano, Kiefer, Flavien, Hara, Nathan, Grupp, Frank, Ehrhardt, Juliana, Murgas, Felipe, Collins, Karen A., Bieryla, Allyson, Parviainen, Hannu, Belinski, Alexandr A., Esparza-Borges, Emma, Ciardi, David R., Clark, Catherine A., Fukui, Akihiko, Gilbert, Emily A., Hopp, Ulrich, Ikuta, Kai, Jenkins, Jon M., Latham, David W., Narita, Norio, Nielsen, Louise D., Quinn, Samuel N., Palle, Enric, Pippert, Jan-Niklas, Polanski, Alex S., Ries, Christoph, Schmidt, Michael, Schwarz, Richard P., Seager, Sara, Strakhov, Ivan A., Striegel, Stephanie, van Eyken, Julian C., Watanabe, Noriharu, Watkins, Cristilyn N., Winn, Joshua N., Ziegler, Carl, and Zöller, Raphael
- Subjects
Astrophysics - Earth and Planetary Astrophysics - Abstract
We report the discovery and characterization of two sub-Saturns from the Transiting Exoplanet Survey Satellite (\textit{TESS}) using high-resolution spectroscopic observations from the MaHPS spectrograph at the Wendelstein Observatory and the SOPHIE spectrograph at the Haute-Provence Observatory. Combining photometry from TESS, KeplerCam, LCOGT, and MuSCAT2 with the radial velocity measurements from MaHPS and SOPHIE we measure precise radii and masses for both planets. TOI-5108 b is a sub-Saturn with a radius of $6.6 \pm 0.1$ $R_\oplus$ and a mass of $32 \pm 5$ $M_\oplus$. TOI-5786 b is similar to Saturn with a radius of $8.54 \pm 0.13$ $R_\oplus$ and a mass of $73 \pm 9$ $M_\oplus$. The host star for TOI-5108 b is a moderately bright (Vmag 9.75) G-type star. TOI-5786 is a slightly dimmer (Vmag 10.2) F-type star. Both planets are close to their host stars with periods of 6.75 days and 12.78 days respectively. This puts TOI-5108 b just inside the bounds of the Neptune desert while TOI-5786 b is right above the upper edge. We estimate hydrogen-helium envelope mass fractions of $38 \%$ for TOI-5108 b and $74 \% $ for TOI-5786 b. However, using a model for the interior structure that includes tidal effects the envelope fraction of TOI-5108 b could be much lower ($\sim 20\,\%$) depending on the obliquity. We estimate mass-loss rates between 1.0 * $10^9$ g/s and 9.8 * $10^9$ g/s for TOI-5108 b and between 3.6 * $10^8$ g/s and 3.5 * $10^9$ g/s for TOI-5786 b. Given their masses, this means that both planets are stable against photoevaporation. We also detect a transit signal for a second planet candidate in the TESS data of TOI-5786 with a period of 6.998 days and a radius of $3.83 \pm 0.16$ $R_\oplus$. Using our RV data and photodynamical modeling, we are able to provide a 3-$\sigma$ upper limit of 26.5 $M_\oplus$ for the mass of the potential inner companion to TOI-5786 b., Comment: 25 pages, 13 figures. Accepted for publication in A&A
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- 2025
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39. Mapping the Three‐Dimensional Nanostructure of the Ionic Liquid–Solid Interface Using Atomic Force Microscopy and Molecular Dynamics Simulations
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Aaron Elbourne, Madeleine Dupont, Rashad Kariuki, Nastaran Meftahi, Torben Daeneke, Tamar L. Greaves, Christopher F. McConville, Gary Bryant, Saffron J. Bryant, Quinn A. Besford, and Andrew J. Christofferson
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atomic force microscopy ,interfacial nanostructures ,ionic liquids ,lateral nanostructures ,mica ,molecular dynamics simulations ,Physics ,QC1-999 ,Technology - Abstract
Abstract Ionic liquids (ILs) are a widely investigated class of solvents for scientific and industrial applications due to their desirable and “tunable” properties. The IL–solid interface is a complex entity, and despite intensive investigation, its true nature remains elusive. The understanding of the IL–solid interface has evolved over the last decade from a simple 1D double layer, to a 2D ordered interface, and finally a liquid‐specific, complex 3D ordered liquid interface. However, most studies depend solely on one technique, which often only examine one aspect of the interfacial nanostructure. Here, a holistic study of the protic IL–solid interface is presented, which provides a more detailed picture of IL interfacial solvation. The 3D nanostructure of the ethylammonium nitrate (EAN)–mica interface is investigated using a combination of 1D, 2D, and 3D amplitude modulated‐atomic force microscopy and molecular dynamics simulations. Importantly, it is found that the EAN–mica interface is more complex than previously reported, possessing surface‐adsorbed, near‐surface, surface‐normal, and lateral heterogeneity, which propagates at relatively large distances from the solid substrate. The work presented in this study meaningfully enhances the understanding of the IL–solid interface.
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- 2023
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40. Identifying Virulence Determinants In Pathogenic Mycobacteria Via Changes In Host Cell Mitochondrial Morphology
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Quinn, Shannon, Abbadi, Amr, Vaezi, Seyed Alireza, Karls, Russell K., and Quinn, Frederick D.
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Quantitative Biology - Subcellular Processes - Abstract
The goal of this study is to develop a computational model of the progression of changes in mitochondrial phenotype resulting from infection with pathogenic mycobacteria. This ultimately will enable a large-scale virulence screen of mutant bacterial libraries. Mycobacterium tuberculosis (Mtb) is an intracellular pathogen, but only a small number of its genes have been studied for roles in intracellular host cell survival and replication. Mitochondria are the powerhouse of the host cell and play critical roles in cell survival when attacked by certain pathogens. When Mtb bacteria invade host cells, they induce changes in mitochondrial morphology, making mitochondria a novel target for image processing and machine learning to determine virulence associations of genes in Mtb and potentially other related intracellular pathogens. By hypothesizing mitochondria as an instance of a dynamic and interconnected graph, we demonstrate a statistical approach for quantitatively recognizing novel mitochondrial phenotypes induced by invading pathogens.
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- 2024
41. Understanding Preschool Educators' Writing Knowledge: Insights from the Early Writing Knowledge Assessment
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Margaret F. Quinn, Gary E. Bingham, Rebecca Rohloff, and Hope K. Gerde
- Abstract
Teachers' knowledge impacts their practices in classrooms. While considerable research has sought to understand teachers' broad emergent literacy knowledge, less is known about the specific knowledge teachers hold regarding early writing. The present study engaged 66 diverse early childhood teachers in five Head Start programs across two states to examine teachers' knowledge for early writing, bringing specificity to our understanding of teachers' knowledge of writing skills and development. To overcome issues of current elicitation materials which employ researcher generated questioning and decontextualized testing formats, we utilized an innovative instrument (The Early Writing Knowledge Assessment: EWKA) to elicit teachers' knowledge and beliefs from three authentic, contextualized child writing samples reflecting distinct, developmental writing skills. Teachers reflected on each sample and responses were coded using a two-step process and an a priori set of codes derived from established early writing theories. Results indicated that generally, teachers' early writing knowledge aligned with research-based conceptualizations, however, wide variation existed in the language used. Patterns existed in the components and subcomponents emphasized depending on the developmental skills demonstrated in the sample. Study findings highlight the wide variability, including inaccuracies, of teachers' early writing knowledge and the inconsistent language used to describe writing development used in the field, both of which have implications for research and practice. Implications for the field, including the potential use of the EWKA to better understand the workforce and for use in professional learning are further discussed.
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- 2025
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42. 'I'm on My Own and I'm Not Trained': A Cultural-Historical Activity Theory Analysis of Teaching Mathematics Out-of-Field in a Small School
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Frances Quinn and Linda Hobbs
- Abstract
This paper employs Cultural Historical Activity Theory (CHAT) as an analytical heuristic in exploring the internationally prevalent situation of teaching out-of-field. Drawing on interview transcripts, we use CHAT to frame the activity of a young teacher teaching mathematics out-of-field in a small rural K-12 school in Australia. We identify and map some important elements and tensions of out-of-field mathematics teaching, how these tensions change over time and how this activity interacts with in-field teaching. Finally, we consider emotions and identity in relation to the structural elements of CHAT mediational triangles to more fully explore and represent some of the complexities of teaching mathematics out-of-field in a small rural school and implications for responding to the out-of-field phenomenon.
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- 2025
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43. Understanding Young Children's Composition across Three Key Components: Transcription, Connection, and Discourse
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Margaret F. Quinn and Rebecca Rohloff
- Abstract
Early writing (i.e. young children's emerging skills prior to the onset of skilled writing) provides important foundations for literacy; however, its components are not evenly understood, assessed, or supported. Transcription skills (handwriting/spelling) are emphasized, while other aspects of composing are often sidelined. Understanding multiple composing components, including transcription, is critical. This study, examining a large corpus of composing samples (N = 394 samples) across two writing tasks, explores composing using a holistic conceptual frame and includes components of transcription in context (handwriting and spelling), connection (relationship between pre- and post-writing verbalizations), and discourse (quantity of ideas expressed). The results demonstrate variable skills (38%-41% of samples using scribbling and drawing; 63%-68% demonstrating connection between pre- and post-writing verbalizations) and further demonstrate that children express more ideas prior to writing, compared to following writing, on average (M = 3.48-4.12 ideas in pre-writing verbalization; M = 2.60-3.13 in post-writing verbalization), suggesting that many children transform and shorten their writing naturalistically and without prompting. Relationships between components were inconsistent (transcription and connection significantly related, ps < 0.05; other relationships were nonsignificant, ps > 0.05). The study provides insights into children's writing processes and has implications for instruction and assessment.
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- 2025
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44. Evidence-Based Instructional Practices for Twice-Exceptional Students with Autism
- Author
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Quinn Austermann, Sally M. Reis, and Julie Delgado
- Abstract
Academically talented students with autism, also known as twice-exceptional students with autism (2eASD), are increasingly identified in school. These students present challenges to educators who attempt to plan and implement successful instructional opportunities, as teachers' knowledge and use of evidence-based practices (EBPs) for students identified with 2eASD vary. The purpose of this qualitative study was to identify current practices used by 10 high-school content and special education teachers who teach these students, as well as their recommendations for postsecondary institutions for these students. The findings suggest high-school teachers support the use of differentiated, strength-based individualized instruction for college-bound students with 2eASD, but are generally unable to offer specific examples of how these practices are implemented in their special education or content classrooms. In addition, they seldom focus on the strengths and talents of this population in their classrooms and fail to recommend competitive colleges for their consideration.
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- 2025
- Full Text
- View/download PDF
45. 'That Fight Still Goes On': Narratives of Integration and Activism
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Darla Linville, Molly Quinn, and Nicoletta Christodoulou
- Abstract
Discussions of Black history and school desegregation in many K-12 schools have been narrowed to a few heroic figures and moments. Historic representations are currently challenged by a nationwide movement to uphold White supremacy and deny the violent history of racism in the US. The revisionist claims are challenged in this qualitative narrative research project that presents stories gathered from 10 Black educators in Augusta, Georgia, who recount their stories of desegregating schools and institutions as students or educators. This oral history narrative project imagines these stories as the basis for engaging K-12 teachers and students in creating new curricula.
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- 2025
- Full Text
- View/download PDF
46. Special issue on 'Ultrasound-assisted engineering of materials for biomedical uses'
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Quinn A. Besford and Francesca Cavalieri
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Chemistry ,QD1-999 ,Acoustics. Sound ,QC221-246 - Published
- 2022
- Full Text
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47. Grass bud responses to fire in a semiarid savanna system
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Quinn A. Hiers, Morgan L. Treadwell, Matthew B. Dickinson, Kathleen L. Kavanagh, Alexandra G. Lodge, Heath D. Starns, Doug R. Tolleson, Dirac Twidwell, Carissa L. Wonkka, and William E. Rogers
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bud dormancy ,fire management ,herbaceous perennial resprouting ,plant mortality ,vegetative tiller reproduction ,Ecology ,QH540-549.5 - Abstract
Abstract Increasingly, land managers have attempted to use extreme prescribed fire as a method to address woody plant encroachment in savanna ecosystems. The effect that these fires have on herbaceous vegetation is poorly understood. We experimentally examined immediate (
- Published
- 2021
- Full Text
- View/download PDF
48. Changes in the expression of inflammatory and epigenetic-modulatory genes after an intensive meditation retreat
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María Jesús Álvarez-López, Quinn A. Conklin, Marta Cosín-Tomás, Grant S. Shields, Brandon G. King, Anthony P. Zanesco, Perla Kaliman, and Clifford D. Saron
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Meditation ,Mindfulness ,Retreat ,Gene expression ,Cytokines ,Epigenetics ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Psychology ,BF1-990 - Abstract
Background: Meditation retreats are characterized by intensive or concentrated periods of meditation practice, commonly undertaken in a residential setting. Although research indicates that meditation training can positively influence physical and mental health outcomes, the biological consequences of meditation retreat interventions are relatively understudied. In this study, we examined the influence of a month-long, silent meditation retreat on the expression of genes involved in epigenetic modulation and immune processes. Method: We assessed gene expression changes in experienced meditators attending a month-long Insight meditation retreat (n = 28), as compared to a community control group (n = 34) of experienced practitioners living their everyday lives. Blood samples were collected on day two of the retreat (Time 1) and again 3 weeks later (Time 2). Control participants were also assessed across a 3-week interval, during which they maintained their regular daily routines. Results: As compared to controls, retreat participants showed differential changes in the expression of several genes involved in chromatin modulation and inflammation. The most substantive finding was downregulation of the TNF pathway in retreat participants, which was not observed in controls. Conclusions: These findings indicate that meditation retreat participation may influence some of the inflammatory mechanisms involved in the development of chronic diseases, and that this style of psychosocial intervention may have therapeutic potential, particularly in experienced practitioners.
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- 2022
- Full Text
- View/download PDF
49. Amyloid-β predominant Alzheimer’s disease neuropathologic change
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Kovacs, Gabor G, Katsumata, Yuriko, Wu, Xian, Aung, Khine Zin, Fardo, David W, Forrest, Shelley L, Bowen, James D, Crane, Paul K, Jarvik, Gail P, Keene, C Dirk, Larson, Eric B, McCormick, Wayne C, McCurry, Susan M, Mukherjee, Shubhabrata, Kowall, Neil W, McKee, Ann C, Stern, Robert A, Baldwin, Clinton T, Farrer, Lindsay A, Jun, Gyungah, Lunetta, Kathryn L, Honig, Lawrence S, Vonsattel, Jean Paul, Williamson, Jennifer, Small, Scott, Barral, Sandra, Reitz, Christiane, Vardarajan, Badri N, Mayeux, Richard, Burke, James R, Hulette, Christine M, Welsh-Bohmer, Kathleen A, Gearing, Marla, Lah, James J, Levey, Allan I, Wingo, Thomas S, Apostolova, Liana G, Farlow, Martin R, Ghetti, Bernardino, Saykin, Andrew J, Spina, Salvatore, Faber, Kelley M, Foroud, Tatiana M, Albert, Marilyn S, Lyketsos, Constantine G, Troncoso, Juan C, Frosch, Matthew P, Green, Robert C, Growdon, John H, Hyman, Bradley T, Tanzi, Rudolph E, Potter, Huntington, Dickson, Dennis W, Ertekin-Taner, Nilufer, Graff-Radford, Neill R, Parisi, Joseph E, Petersen, Ronald C, Boeve, Bradley F, Allen, Mariet, Carrasquillo, Minerva M, Younkin, Steven G, Duara, Ranjan, Buxbaum, Joseph D, Goate, Alison M, Sano, Mary, Masurkar, Arjun V, Wisniewski, Thomas, Bigio, Eileen H, Mesulam, Marsel, Weintraub, Sandra, Vassar, Robert, Kaye, Jeffrey A, Quinn, Joseph F, Woltjer, Randall L, Barnes, Lisa L, Yu, Lei, Evans, Denis A, Henderson, Victor, Fallon, Kenneth B, Harrell, Lindy E, Marson, Daniel C, Roberson, Erik D, DeCarli, Charles, Jin, Lee-Way, Olichney, John M, Kim, Ronald, LaFerla, Frank M, Monuki, Edwin, Head, Elizabeth, Sultzer, David, Geschwind, Daniel H, Vinters, Harry V, Chesselet, Marie-Francoise, Galasko, Douglas R, Brewer, James B, Boxer, Adam, Karydas, Anna, Kramer, Joel H, Miller, Bruce L, and Rosen, Howard J
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Biomedical and Clinical Sciences ,Health Sciences ,Psychology ,Aging ,Genetics ,Neurosciences ,Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) ,Alzheimer's Disease ,Acquired Cognitive Impairment ,Neurodegenerative ,Dementia ,Brain Disorders ,2.1 Biological and endogenous factors ,Neurological ,Humans ,Alzheimer Disease ,Female ,Aged ,Male ,Aged ,80 and over ,Amyloid beta-Peptides ,Plaque ,Amyloid ,tau Proteins ,Neurofibrillary Tangles ,Brain ,Alzheimer's Disease Genetics Consortium ,ADGC ,NACC ,amyloid-β ,biomarker ,diffuse plaques ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Neurology & Neurosurgery ,Biomedical and clinical sciences ,Health sciences - Abstract
Different subsets of Alzheimer's disease neuropathologic change (ADNC), including the intriguing set of individuals with severe/widespread amyloid-β (Aβ) plaques but no/mild tau tangles [Aβ-predominant (AP)-ADNC], may have distinct genetic and clinical features. Analysing National Alzheimer's Coordinating Center data, we stratified 1187 participants into AP-ADNC (n = 95), low Braak primary age-related tauopathy (PART; n = 185), typical-ADNC (n = 832) and high-Braak PART (n = 75). AP-ADNC differed in some clinical features and genetic polymorphisms in the APOE, SNX1, WNT3/MAPT and IGH genes. We conclude that AP-ADNC differs from classical ADNC with implications for in vivo studies.
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- 2025
50. Judgements of identity claims vary for monoracial and biracial people
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Quinn‐Jensen, Elizabeth A and Liberman, Zoe
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Clinical and Health Psychology ,Psychology ,Health Disparities ,Minority Health ,biracial ,contextual presentation ,identity flexibility ,racial identity ,Developmental & Child Psychology ,Applied and developmental psychology ,Biological psychology ,Social and personality psychology - Abstract
Abstract: Despite increasing racial diversity in the United States, and the particular growth of multiracial populations, questions about how children perceive others’ (bi)racial identities remain poorly understood. In two preregistered studies, we asked White and racially minoritized American children (N = 157; 4–11‐years old) and White and multiracial adults (N = 226) how acceptable it was for monoracial people (Black or White; Study 1) and/or biracial people (Black–White; Studies 1 and 2) to claim either a monoracial or biracial identity. Consistent with past research with adults, children said that monoracial people should claim (only) the monoracial identity which matched their ancestry. Judgements about biracial identity were more variable. White and multiracial adults (Study 2) reported that biracial targets could claim a racial identity that matched either or both of their parents, with biracial claims being evaluated most positively. Exploratory analyses on children's judgements about biracial people's identity claims (Study 1) revealed different patterns of development for White children and children from minoritized backgrounds. Whereas White children became more likely with age to report that all identity claims were acceptable, children from racially minoritized groups became more likely with age to endorse biracial targets who claimed a biracial identity. These findings suggest that children's own racial background and age may have a larger impact on their perceptions of biracial people's identities, compared to their perceptions of monoracial people's identities.
- Published
- 2025
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