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Taking the upper sub-member of Sha 4 in Well Fanye 1 and Well Niuye 1 in Dongying Sag, Jiyang Depression, Bohai Bay Basin as a typical example, this paper adopts the method of combining macro and micro laminar characterization and complementing each other. The characteristics of laminar development are studied by means of fine description of rock thin sections by cores and electron microscopic observation Reconstruction of the Bohai Bay Basin in sand four period of ancient sedimentary environment, it is concluded that the sand on the four period of development of four complete filling sedimentary cycle. Using Milankovitch cycles method, reveals the ancient climate control mechanism of lithofacies, formed by organic laminae under hot and humid climate and a small amount of calcite laminated lithofacies, in hot and humid climate, the lithofacies is mainly composed of organic lamina and a small amount of calcite lamina, while in cold and dry climate, the lithofacies is mainly composed of calcite lamina, and the lithofacies is mainly composed of organic lamina, silty lamina and gypsum lamina. Micro-laminar research is an important scientific issue in unconventional oil and gas eology. It can provide basic data for unconventional oil and gas exploration, such as the types, distribution and extension of laminar, especially the determination of sampling targets. Different laboratory samples can be analyzed according to the laminar types.

Acupuncture treatment can regulate blood pressure (BP) through multiple levels and ways. In the present paper, we reviewed the progress of researches on the underlying mechanisms of acupuncture in lowering BP from 1) regulation of activities of the neuroendocrine, 2) improvement of metabolic abnormality, and 3) alternation of gene expression in the heart and BP-regulation-related centers of the brain. The neuroendocrine mechanism mainly involves the inhibition of neuroinflammatory reaction in some higher brain regions, reduction of neuronal apoptosis, and suppression of the sympathetic cardiovascular regulatory functional areas of the brain stem, regulation of neurotransmitters and autonomic balance, activation of brain areas related to BP regulation, and promotion of functional connection between brain networks. The improvement of metabolic abnormality mainly refers to amelioration of imbalance of intestinal flora and target metabolites related to hypertension. The alteration of gene expression mainly manifests as up- and down-regulation of expression of genes related to oxidative stress, inflammation and vascular endothelial function in the myocardium, hypothalamus, rostral ventrolateral medulla. We reviewed the new research progress on the mechanism of acupuncture for hypertension, in order to provide evidence and research ideas for the treatment of related cardiovascular diseases by using acupuncture therapy in the future.针刺可通过多水平、多途径对血压进行调节。近年来，针刺的降压机制研究更多地集中在调节神经-内分泌、改善代谢紊乱和改变基因表达上。针刺的神经-内分泌机制包括抑制大脑神经炎性反应及神经元凋亡、抑制脑干交感调节功能区并调节相关神经递质、激活血压调节相关脑区、促进功能脑区联系以及影响自主神经功能状态等；改善代谢紊乱主要体现在对肠道菌群结构和高血压相关的靶代谢产物方面的影响；改变基因表达主要表现为调节与氧化应激、炎性反应和血管内皮功能相关的基因表达。本文就针刺降压机制的国内外研究新进展进行综述，以期为今后针刺在相关心血管疾病中的临床应用提供理论依据。.