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Your search keyword '"PulseWave Velocity"' showing total 5 results
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5 results on '"PulseWave Velocity"'

1. Lack of acute or chronic effects of epicatechin-rich and procyanidin-rich apple extracts on blood pressure and cardiometabolic biomarkers in adults with moderately elevated blood pressure: a randomized, placebo-controlled crossover trial.

Author

Hollands, Wendy J, Tapp, Henri, Defernez, Marianne, Moral, Natalia Perez, Winterbone, Mark S, Philo, Mark, Lucey, Alice J, Kiely, Mairead E, and Kroon, Paul A

Subjects
EPICATECHIN, PROCYANIDINS, BIOLOGICAL tags, POLYPHENOLS, APPLES, ARTERIAL diseases, BIOMARKERS, BLOOD pressure, CARBOHYDRATES, CARDIOVASCULAR diseases, CARDIOVASCULAR diseases risk factors, ENDOTHELINS, FLAVONOIDS, HIGH density lipoproteins, HYPERTENSION, LOW density lipoproteins, NITRIC oxide, TRIGLYCERIDES, PLANT extracts, RANDOMIZED controlled trials, BLIND experiment, SEVERITY of illness index
Abstract

Background: The reported effects of flavanol-rich foods such as cocoa, dark chocolate, and apples on blood pressure and endothelial function may be due to the monomeric flavanols [mainly (-)-epicatechin (EC)], the oligomeric flavanols [procyanidins (PCs)], or other components. Reports of well-controlled intervention studies that test the effects of isolated oligomeric flavanols on biomarkers of cardiovascular health are lacking. Objective: We studied the acute and chronic effects of an ECrich apple flavanol extract and isolated apple PCs on systolic blood pressure (BP) and other cardiometabolic biomarkers. Design: Forty-two healthymen andwomenwith moderately elevated BP completed this randomized, double-blind, placebo-controlled, 4-arm crossover trial. Participants ingested a single dose of an apple flavanol extract (70 mg monomeric flavanols, 65 mg PCs), a double dose of this extract (140 mg monomeric flavanols, 130 mg PCs), an apple PC extract (130 mg PCs, 6.5 mg monomeric flavanols), or placebo capsules once daily for 4 wk, in random order. Biomarkers of cardiovascular disease risk and vascular function were measured before and 2 h after ingestion of the first dose and after the 4-wk intervention. Results: Compared with placebo, none of the isolated flavanol treatments significantly (P < 0.05) changed systolic or diastolic BP (peripheral and aortic), plasma nitric oxide (NO) reaction products, or measures of arterial stiffness (carotid femoral pulsewave velocity, brachial-ankle pulse-wave velocity, or Augmentation Index) after 2 h or 4 wk of the intervention. There were no changes in plasma endogenous metabolite profiles or circulating NO; endothelin 1; total, HDL, or LDL cholesterol; triglycerides; fasting glucose; fructosamine; or insulin after 4 wk of the intervention. Conclusions: Our data suggest that, in isolation, neither monomeric flavanols nor PCs affect BP, blood lipid profiles, endothelial function, or glucose control in individuals with moderately elevated BP. The reported benefits of consuming flavanol-rich cocoa, chocolate, and apple products appear to be dependent on other components, which may work in combination with monomeric flavanols and PCs. [ABSTRACT FROM AUTHOR]

Published
2018
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3. Arterial stiffness is increased in patients with inflammatory bowel disease

Author

Luca Zanoli, Marcella Di Gangi, Gaetano Inserra, Stéphane Laurent, Mariarita Cannavò, Pietro Castellino, Pierre Boutouyrie, Stefania Rastelli, Ines Monte, and Luigi Di Pino

Subjects
Adult, Male, medicine.medical_specialty, Physiology, Inflammatory bowel disease, Vascular remodelling in the embryo, Vascular Stiffness, Internal medicine, Internal Medicine, medicine, Humans, In patient, cardiovascular diseases, Vascular stiffness, PulseWave Velocity, Pulse wave velocity, business.industry, Case-control study, Middle Aged, medicine.disease, Inflammatory Bowel Diseases, Confidence interval, Surgery, Pulse pressure, Case-Control Studies, cardiovascular system, Cardiology, Arterial stiffness, Female, Cardiology and Cardiovascular Medicine, business
Abstract

Recent studies have reported early atherosclerosis in patients with inflammatory bowel disease (IBD). In these patients, the chronic low-grade inflammation may predispose to vascular remodelling and arterial stiffening. We aimed at studying arterial stiffness in IBD patients.Thirty-two IBD patients without cardiovascular risk factors and 32 matched controls were enrolled (age 19-49 years). SphygmoCor device (AtCor Medical, Sydney, Australia) was used to measure carotid-femoral and carotid-radial (muscular artery) pulse wave velocity (PWV), augmentation index and central blood pressure.Carotid-femoral PWV was higher in IBD patients than in controls (6.6 ± 1.4 vs. 6.0 ± 0.8 m/s, respectively, P 0.05), as well as carotid-radial PWV (8.5 ± 1.2 vs. 7.2 ± 1.0 m/s, P 0.001). Central pulse pressure was higher in IBD than in controls (32 ± 6 vs. 28 ± 7 mmHg, P 0.05). Aging was an important determinant of carotid-femoral PWV in both groups and carotid-radial PWV only in IBD patients. In fully adjusted model performed in both groups of patients considered as a whole, age was positively associated with carotid-femoral PWV [R(2) = 0.10; +0.05 m/s per 1 year of aging, 95% confidence interval (CI) 0.01-0.08 m/s, P 0.05], as well as IBD (R(2) = 0.10; +0.72 m/s if IBD present, 95% CI 0.19-1.26 m/s, P 0.05). In IBD patients, carotid-radial PWV was positively associated with the disease duration (R(2) = 0.20; +0.11 m/s per 1 year of aging, 95% CI 0.03-0.19 m/s, P 0.05).Arterial stiffness is increased in patients with IBD independently of conventional cardiovascular risk factors.

Published
2012

4. Pulse wave velocity in Endemic (Balkan) Nephropathy patients undergoing hemodialysis

Author

Premužić, Vedran, Laganović, Mario, Kovač-Peić, Ana-Marija, Leko, Ninoslav, Čvoriščec, Dubravka, Pohl, Tibor, Pećin, Ivan, and Jelaković, Bojan

Subjects
musculoskeletal diseases, animal structures, technology, industry, and agriculture, macromolecular substances, equipment and supplies, pulsewave velocity, hemodialysis, endemic nephropathy
Abstract

Arterial stiffness is a strong predictor of cardiovascular outcome, especially in hemodialysis patients. Our aim was to determine arterial stiffness in endemic nephropathy patients undergoing hemodialysis

Published
2009

5. Arterial characteristics in normotensive offspring of parents with or without a history of hypertension

Author

Wiktoria Wojciechowska, Robert Fagard, Jan A. Staessen, Jitka Kucerová, Kalina Kawecka-Jaszcz, Jan Filipovský, M. Dolejšová, Marcin Cwynar, Tomasz Grodzicki, Katarzyna Stolarz, Tatiana Kuznetsova, and Jerzy Gasowski

Subjects
Adult, Male, medicine.medical_specialty, Mean arterial pressure, Adolescent, Offspring, Hemodynamics, Blood Pressure, augmentation index, Internal medicine, Internal Medicine, medicine, Humans, Systole, Pulse, Pulse wave velocity, pulsewave velocity, offspring, business.industry, Arteries, Blood Pressure Monitoring, Ambulatory, Pulse pressure, Endocrinology, Blood pressure, Cross-Sectional Studies, Ambulatory, Hypertension, Adult Children, Female, business
Abstract

BACKGROUND: In this study we compared the arterial characteristics and blood pressure (BP) of normotensive offspring of two normotensive parents (OFF/NT) and normotensive offspring who had at least one hypertensive parent (OFF/HT). METHODS: A total of 174 OFF/HT (17 to 40 years of age) and 59 OFF/NT (16 to 34 years) were recruited in Cracow, Poland (n = 138) and Pilsen, Czech Republic (n = 95). Peripheral pulse pressure (PPp) was determined from conventional and 24-h ambulatory BP. A SphygmoCor device was used to measure the central (CAIx) and peripheral (PAIx) systolic augmentation indexes, central pulse pressure (PPc), and the aortic pulse wave velocity (PWV). In multivariate analyses family clusters and significant covariates were accounted for. RESULTS: The OFF/HT had higher (.14 < P < .0007) conventional BP and PPp on conventional BP measurement (121/75 v 114/71 mm Hg and 46 v 42 mm Hg) as well as on 24-h ambulatory monitoring (118/70 v 114/67 mm Hg and 48 v 47 mm Hg). OFF/HT, compared with OFF/NT, also had higher (.05 < P < .0008) PPc (28 v 26 mm Hg), PAIx (54.7% v 44.9%), CAIx (108.8% v 99.8%), and PWV (7.4 v 6.6 m/sec). However, complex adjustment including mean arterial pressure and age removed the differences between the offspring in the PAIx, CAIx, and PWV. CONCLUSIONS: Large-artery properties are altered in OFF/HT compared with OFF/NT. The findings from this cross-sectional study suggest that the alterations in arterial function in subjects with a family history of hypertension are determined mainly by an increased BP and age-related hemodynamic changes. ispartof: American Journal of Hypertension vol:19 issue:3 pages:264-269 ispartof: location:United States status: published

Published
2005

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