1. [Essential Tremor: Update of Therapeutic Strategies].
- Author
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Gironell A, Marín-Lahoz J, and Póveda S
- Subjects
- Humans, Propranolol therapeutic use, Primidone therapeutic use, High-Intensity Focused Ultrasound Ablation, Anticonvulsants therapeutic use, Thalamus, Adrenergic beta-Antagonists therapeutic use, Essential Tremor therapy, Essential Tremor drug therapy
- Abstract
In the last decades there has been progress in the treatment of essential tremor (TE) especially in the surgical field and to a lesser extent in the pharmacological field. We carry out a review of the currently available treatments. The first intervention is the use of non-pharmacological and non-surgical strategies (general advice, occupational therapy, speech therapy, psychotherapy). With discrete advances, the pharmacological treatment is not very satisfactory. Only 30-60% of patients have a positive response, and in these the anti-tremor effectiveness is 40-60%. The first-line drugs are still propranolol and primidone. In cases with severe tremor we will consider a surgical option, the method of choice being thalamotomy using high-intensity focused ultrasound. In the future we must continue to study the pathophysiology of TE, develop drugs specifically designed for TE and improve the technology of available invasive techniques., (Copyright © 2024 Elsevier España, S.L.U. All rights reserved.)
- Published
- 2024
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