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Essential tremor leading to toxic liver damage successfully treated with deep brain stimulation.
- Source :
-
Acta neurochirurgica [Acta Neurochir (Wien)] 2009 Oct; Vol. 151 (10), pp. 1305-7. Date of Electronic Publication: 2009 Mar 17. - Publication Year :
- 2009
-
Abstract
- Purpose: We present a patient with severe essential tremor (ET), who underwent thalamic deep brain stimulation (DBS). After previous medical treatment with Propranolol and Primidone failed, the patient resorted to alcohol, which greatly alleviated the symptoms. The downside of this situation, however, was that it led to alcoholism with severely disturbed liver enzymes and hepatic steatosis.<br />Methods & Results: After DBS the patient was free of tremor and thus could easily abstain from alcohol.<br />Conclusion: In time the elevated liver enzymes returned to normal, which indicates that sufficient tremor control by DBS can help these patients to abstain from alcohol.
- Subjects :
- Adrenergic beta-Antagonists therapeutic use
Aged
Alcoholism etiology
Anticonvulsants therapeutic use
Central Nervous System Depressants therapeutic use
Essential Tremor physiopathology
Ethanol therapeutic use
Humans
Liver diagnostic imaging
Liver drug effects
Liver physiopathology
Liver Diseases, Alcoholic pathology
Male
Neural Pathways physiology
Neurosurgical Procedures
Primidone therapeutic use
Propranolol therapeutic use
Stereotaxic Techniques
Treatment Failure
Treatment Outcome
Ultrasonography
Ventral Thalamic Nuclei anatomy & histology
Ventral Thalamic Nuclei physiology
Ventral Thalamic Nuclei surgery
Alcoholism complications
Central Nervous System Depressants adverse effects
Deep Brain Stimulation methods
Essential Tremor therapy
Ethanol adverse effects
Liver Diseases, Alcoholic physiopathology
Subjects
Details
- Language :
- English
- ISSN :
- 0942-0940
- Volume :
- 151
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Acta neurochirurgica
- Publication Type :
- Academic Journal
- Accession number :
- 19290467
- Full Text :
- https://doi.org/10.1007/s00701-009-0249-x