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4. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight

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Iurilli, M.L.C. Zhou, B. Bennett, J.E. Carrillo-Larco, R.M. Sophiea, M.K. Rodriguez-Martinez, A. Bixby, H. Solomon, B.D. Taddei, C. Danaei, G. Di Cesare, M. Stevens, G.A. Riley, L.M. Savin, S. Cowan, M.J. Bovet, P. Damasceno, A. Chirita-Emandi, A. Hayes, A.J. Ikeda, N. Jackson, R.T. Khang, Y.-H. Laxmaiah, A. Liu, J. Miranda, J.J. Saidi, O. Sebert, S. Sorić, M. Starc, G. Gregg, E.W. Abarca-Gómez, L. Abdeen, Z.A. Abdrakhmanova, S. Ghaffar, S.A. Rahim, H.F.A. Abu-Rmeileh, N.M. Garba, J.A. Acosta-Cazares, B. Adams, R.J. Aekplakorn, W. Afsana, K. Afzal, S. Agdeppa, I.A. Aghazadeh-Attari, J. Aguilar-Salinas, C.A. Agyemang, C. Ahmad, M.H. Ahmad, N.A. Ahmadi, A. Ahmadi, N. Ahmed, S.H. Ahrens, W. Aitmurzaeva, G. Ajlouni, K. Al-Hazzaa, H.M. Al-Lahou, B. Al-Raddadi, R. Alarouj, M. AlBuhairan, F. AlDhukair, S. Ali, M.M. Alkandari, A. Alkerwi, A. Allin, K. Alvarez-Pedrerol, M. Aly, E. Amarapurkar, D.N. Amiri, P. Amougou, N. Amouyel, P. Andersen, L.B. Anderssen, S.A. Ängquist, L. Anjana, R.M. Ansari-Moghaddam, A. Aounallah-Skhiri, H. Araújo, J. Ariansen, I. Aris, T. Arku, R.E. Arlappa, N. Aryal, K.K. Aspelund, T. Assah, F.K. Assunção, M.C.F. Aung, M.S. Auvinen, J. Mária Avdicová Avi, S. Azevedo, A. Azimi-Nezhad, M. Azizi, F. Azmin, M. Babu, B.V. Bæksgaard Jørgensen, M. Baharudin, A. Bahijri, S. Baker, J.L. Balakrishna, N. Bamoshmoosh, M. Banach, M. Bandosz, P. Banegas, J.R. Baran, J. Barbagallo, C.M. Barceló, A. Barkat, A. Barros, A.J.D. Barros, M.V.G. Basit, A. Bastos, J.L.D. Bata, I. Batieha, A.M. Batista, R.L. Battakova, Z. Batyrbek, A. Baur, L.A. Beaglehole, R. Bel-Serrat, S. Belavendra, A. Romdhane, H.B. Benedics, J. Benet, M. Bergh, I.H. Berkinbayev, S. Bernabe-Ortiz, A. Bernotiene, G. Bettiol, H. Bezerra, J. Bhagyalaxmi, A. Bharadwaj, S. Bhargava, S.K. Bhutta, Z.A. Bi, H. Bi, Y. Bia, D. Lele, E.C.B. Bikbov, M.M. Bista, B. Bjelica, D.J. Bjerregaard, P. Bjertness, E. Bjertness, M.B. Björkelund, C. Bloch, K.V. Blokstra, A. Bo, S. Bobak, M. Boddy, L.M. Boehm, B.O. Boeing, H. Boggia, J.G. Bogova, E. Boissonnet, C.P. Bojesen, S.E. Bonaccio, M. Bongard, V. Bonilla-Vargas, A. Bopp, M. Borghs, H. Braeckevelt, L. Braeckman, L. Bragt, M.C.E. Brajkovich, I. Branca, F. Breckenkamp, J. Breda, J. Brenner, H. Brewster, L.M. Brian, G.R. Brinduse, L. Brophy, S. Bruno, G. Bueno-de-Mesquita, H.B. Bugge, A. Buoncristiano, M. Burazeri, G. Burns, C. de León, A.C. Cacciottolo, J. Cai, H. Cama, T. Cameron, C. Camolas, J. Can, G. Candido, A.P.C. Cañete, F. Capanzana, M.V. Capková, N. Capuano, E. Capuano, V. Cardol, M. Cardoso, V.C. Carlsson, A.C. Carmuega, E. Carvalho, J. Casajús, J.A. Casanueva, F.F. Celikcan, E. Censi, L. Cervantes-Loaiza, M. Cesar, J.A. Chamukuttan, S. Chan, A.W. Chan, Q. Chaturvedi, H.K. Chaturvedi, N. Rahim, N.C.A. Chee, M.L. Chen, C.-J. Chen, F. Chen, H. Chen, S. Chen, Z. Cheng, C.-Y. Cheraghian, B. Chetrit, A. Chikova-Iscener, E. Chiolero, A. Chiou, S.-T. Chirlaque, M.-D. Cho, B. Christensen, K. Christofaro, D.G. Chudek, J. Cifkova, R. Cilia, M. Cinteza, E. Claessens, F. Clarke, J. Clays, E. Cohen, E. Concin, H. Confortin, S.C. Cooper, C. Coppinger, T.C. Corpeleijn, E. Costanzo, S. Cottel, D. Cowell, C. Craig, C.L. Crampin, A.C. Crujeiras, A.B. Csilla, S. Cucu, A.M. Cui, L. Cureau, F.V. Czenczek-Lewandowska, E. D’Arrigo, G. d’Orsi, E. Dacica, L. Dal Re Saavedra, M.A. Dallongeville, J. Damsgaard, C.T. Dankner, R. Dantoft, T.M. Dasgupta, P. Dastgiri, S. Dauchet, L. Davletov, K. De Backer, G. De Bacquer, D. de Gaetano, G. De Henauw, S. de Oliveira, P.D. De Ridder, D. De Ridder, K. de Rooij, S.R. De Smedt, D. Deepa, M. Deev, A.D. DeGennaro, V., Jr Dehghan, A. Delisle, H. Delpeuch, F. Demarest, S. Dennison, E. Dereń, K. Deschamps, V. Dhimal, M. Di Castelnuovo, A.F. Dias-da-Costa, J.S. Díaz-Sánchez, M.E. Diaz, A. Dika, Z. Djalalinia, S. Djordjic, V. Do, H.T.P. Dobson, A.J. Donati, M.B. Donfrancesco, C. Donoso, S.P. Döring, A. Dorobantu, M. Dorosty, A.R. Doua, K. Dragano, N. Drygas, W. Duan, J.L. Duante, C.A. Duboz, P. Duda, R.B. Duleva, V. Dulskiene, V. Dumith, S.C. Dushpanova, A. Dzerve, V. Dziankowska-Zaborszczyk, E. Eddie, R. Eftekhar, E. Egbagbe, E.E. Eggertsen, R. Eghtesad, S. Eiben, G. Ekelund, U. El-Khateeb, M. Ati, J.E. Eldemire-Shearer, D. Eliasen, M. Elliott, P. Engle-Stone, R. Enguerran, M. Erasmus, R.T. Erbel, R. Erem, C. Eriksen, L. Eriksson, J.G. Escobedo-de la Peña, J. Eslami, S. Esmaeili, A. Evans, A. Faeh, D. Fakhretdinova, A.A. Fall, C.H. Faramarzi, E. Farjam, M. Sant’Angelo, V.F. Farzadfar, F. Fattahi, M.R. Fawwad, A. Felix-Redondo, F.J. Ferguson, T.S. Fernandes, R.A. Fernández-Bergés, D. Ferrante, D. Ferrao, T. Ferrari, M. Ferrario, M.M. Ferreccio, C. Ferrer, E. Ferrieres, J. Figueiró, T.H. Fijalkowska, A. Fink, G. Fischer, K. Foo, L.H. Forsner, M. Fouad, H.M. Francis, D.K. Maria do Carmo Franco Frikke-Schmidt, R. Frontera, G. Fuchs, F.D. Fuchs, S.C. Fujiati, I.I. Fujita, Y. Fumihiko, M. Furusawa, T. Gaciong, Z. Gafencu, M. Galbarczyk, A. Galenkamp, H. Galeone, D. Galfo, M. Galvano, F. Gao, J. Garcia-de-la-Hera, M. García-Solano, M. Gareta, D. Garnett, S.P. Gaspoz, J.-M. Gasull, M. Gaya, A.C.A. Gaya, A.R. Gazzinelli, A. Gehring, U. Geiger, H. Geleijnse, J.M. Ghanbari, A. Ghasemi, E. Gheorghe-Fronea, O.-F. Giampaoli, S. Gianfagna, F. Gill, T.K. Giovannelli, J. Gironella, G. Giwercman, A. Gkiouras, K. Godos, J. Gogen, S. Goldberg, M. Goldsmith, R.A. Goltzman, D. Gómez, S.F. Gomula, A. da Silva, B.G.C. Gonçalves, H. Gonzalez-Chica, D.A. Gonzalez-Gross, M. González-Leon, M. González-Rivas, J.P. González-Villalpando, C. González-Villalpando, M.-E. Gonzalez, A.R. Gottrand, F. Graça, A.P. Graff-Iversen, S. Grafnetter, D. Grajda, A. Grammatikopoulou, M.G. Gregor, R.D. Grodzicki, T. Grøholt, E.K. Grøntved, A. Grosso, G. Gruden, G. Gu, D. Gualdi-Russo, E. Guallar-Castillón, P. Gualtieri, A. Gudmundsson, E.F. Gudnason, V. Guerrero, R. Guessous, I. Guimaraes, A.L. Gulliford, M.C. Gunnlaugsdottir, J. Gunter, M.J. Guo, X.-H. Guo, Y. Gupta, P.C. Gupta, R. Gureje, O. Gurzkowska, B. Gutiérrez-González, E. Gutierrez, L. Gutzwiller, F. Ha, S. Hadaegh, F. Hadjigeorgiou, C.A. Haghshenas, R. Hakimi, H. Halkjær, J. Hambleton, I.R. Hamzeh, B. Hange, D. Hanif, A.A.M. Hantunen, S. Hao, J. Kumar, R.H. Hashemi-Shahri, S.M. Hassapidou, M. Hata, J. Haugsgjerd, T. He, J. He, Y. He, Y. Heidinger-Felso, R. Heinen, M. Hejgaard, T. Hendriks, M.E. dos Santos Henrique, R. Henriques, A. Cadena, L.H. Herrala, S. Herrera, V.M. Herter-Aeberli, I. Heshmat, R. Hill, A.G. Ho, S.Y. Ho, S.C. Hobbs, M. Holdsworth, M. Homayounfar, R. Homs, C. Hopman, W.M. Horimoto, A.R.V.R. Hormiga, C.M. Horta, B.L. Houti, L. Howitt, C. Htay, T.T. Htet, A.S. Htike, M.M.T. Hu, Y. Huerta, J.M. Huhtaniemi, I.T. Huiart, L. Petrescu, C.H. Huisman, M. Husseini, A. Huu, C.N. Huybrechts, I. Hwalla, N. Hyska, J. Iacoviello, L. Ibarluzea, J.M. Ibrahim, M.M. Wong, N.I. Ikram, M.A. Iotova, V. Irazola, V.E. Ishida, T. Islam, M. Islam, S.M.S. Iwasaki, M. Jacobs, J.M. Jaddou, H.Y. Jafar, T. James, K. Jamil, K.M. Jamrozik, K. Janszky, I. Janus, E. Jarani, J. Jarvelin, M.-R. Jasienska, G. Jelakovic, A. Jelakovic, B. Jennings, G. Jha, A.K. Jiang, C.Q. Jimenez, R.O. Jöckel, K.-H. Joffres, M. Johansson, M. Jokelainen, J.J. Jonas, J.B. Jonnagaddala, J. Jørgensen, T. Joshi, P. Joukar, F. Jovic, D.P. Jóźwiak, J.J. Juolevi, A. Jurak, G. Simina, I.J. Juresa, V. Kaaks, R. Kaducu, F.O. Kafatos, A. Kajantie, E.O. Kalmatayeva, Z. Kalter-Leibovici, O. Kameli, Y. Kampmann, F.B. Kanala, K.R. Kannan, S. Kapantais, E. Karakosta, A. Kårhus, L.L. Karki, K.B. Katibeh, M. Katz, J. Katzmarzyk, P.T. Kauhanen, J. Kaur, P. Kavousi, M. Kazakbaeva, G.M. Keil, U. Boker, L.K. Keinänen-Kiukaanniemi, S. Kelishadi, R. Kelleher, C. Kemper, H.C.G. Kengne, A.P. Keramati, M. Kerimkulova, A. Kersting, M. Key, T. Khader, Y.S. Khalili, D. Khaw, K.-T. Kheiri, B. Kheradmand, M. Khosravi, A. Khouw, I.M.S.L. Kiechl-Kohlendorfer, U. Kiechl, S. Killewo, J. Kim, D.W. Kim, H.C. Kim, J. Kindblom, J.M. Klakk, H. Klimek, M. Klimont, J. Klumbiene, J. Knoflach, M. Koirala, B. Kolle, E. Kolsteren, P. König, J. Korpelainen, R. Korrovits, P. Korzycka, M. Kos, J. Koskinen, S. Kouda, K. Kovacs, V.A. Kowlessur, S. Koziel, S. Kratenova, J. Kratzer, W. Kriemler, S. Kristensen, P.L. Krokstad, S. Kromhout, D. Kruger, H.S. Kubinova, R. Kuciene, R. Kujala, U.M. Kujundzic, E. Kulaga, Z. Kumar, R.K. Kunešová, M. Kurjata, P. Kusuma, Y.S. Kuulasmaa, K. Kyobutungi, C. La, Q.N. Laamiri, F.Z. Laatikainen, T. Lachat, C. Laid, Y. Lam, T.H. Lambrinou, C.-P. Landais, E. Lanska, V. Lappas, G. Larijani, B. Latt, T.S. Lauria, L. Lazo-Porras, M. Le Coroller, G. Bao, K.L.N. Le Port, A. Le, T.D. Lee, J. Lee, J. Lee, P.H. Lehmann, N. Lehtimäki, T. Lemogoum, D. Levitt, N.S. Li, Y. Liivak, M. Lilly, C.L. Lim, W.-Y. Lima-Costa, M.F. Lin, H.-H. Lin, X. Lin, Y.-T. Lind, L. Linneberg, A. Lissner, L. Litwin, M. Liu, L. Lo, W.-C. Loit, H.-M. Long, K.Q. Lopes, L. Lopes, O. Lopez-Garcia, E. Lopez, T. Lotufo, P.A. Lozano, J.E. Lukrafka, J.L. Luksiene, D. Lundqvist, A. Lundqvist, R. Lunet, N. Lunogelo, C. Lustigová, M. Łuszczki, E. Ma, G. Ma, J. Ma, X. Machado-Coelho, G.L.L. Machado-Rodrigues, A.M. Macieira, L.M. Madar, A.A. Maggi, S. Magliano, D.J. Magnacca, S. Magriplis, E. Mahasampath, G. Maire, B. Majer, M. Makdisse, M. Mäki, P. Malekzadeh, F. Malekzadeh, R. Malhotra, R. Rao, K.M. Malyutina, S.K. Maniego, L.V. Manios, Y. Mann, J.I. Mansour-Ghanaei, F. Manzato, E. Margozzini, P. Markaki, A. Markey, O. Ioannidou, E.M. Marques-Vidal, P. Marques, L.P. Marrugat, J. Martin-Prevel, Y. Martin, R. Martorell, R. Martos, E. Maruszczak, K. Marventano, S. Mascarenhas, L.P. Masoodi, S.R. Mathiesen, E.B. Mathur, P. Matijasevich, A. Matsha, T.E. Mavrogianni, C. Mazur, A. Mbanya, J.C.N. McFarlane, S.R. McGarvey, S.T. McKee, M. McLachlan, S. McLean, R.M. McLean, S.B. McNulty, B.A. Benchekor, S.M. Medzioniene, J. Mehdipour, P. Mehlig, K. Mehrparvar, A.H. Meirhaeghe, A. Meisfjord, J. Meisinger, C. Menezes, A.M.B. Menon, G.R. Mensink, G.B.M. Menzano, M.T. Mereke, A. Meshram, I.I. Metspalu, A. Meyer, H.E. Mi, J. Michaelsen, K.F. Michels, N. Mikkel, K. Milkowska, K. Miller, J.C. Minderico, C.S. Mini, G.K. Miquel, J.F. Mirjalili, M.R. Mirkopoulou, D. Mirrakhimov, E. Mišigoj-Durakovic, M. Mistretta, A. Mocanu, V. Modesti, P.A. Moghaddam, S.S. Mohajer, B. Mohamed, M.K. Mohamed, S.F. Mohammad, K. Mohammadi, Z. Mohammadifard, N. Mohammadpourhodki, R. Mohan, V. Mohanna, S. Yusoff, M.F.M. Mohebbi, I. Mohebi, F. Moitry, M. Molbo, D. Møllehave, L.T. Møller, N.C. Molnár, D. Momenan, A. Mondo, C.K. Monroy-Valle, M. Monterrubio-Flores, E. Monyeki, K.D.K. Moon, J.S. Moosazadeh, M. Moreira, L.B. Morejon, A. Moreno, L.A. Morgan, K. Morin, S.N. Mortensen, E.L. Moschonis, G. Mossakowska, M. Mostafa, A. Mota-Pinto, A. Mota, J. Motlagh, M.E. Motta, J. Moura-dos-Santos, M.A. Mridha, M.K. Msyamboza, K.P. Mu, T.T. Muc, M. Mugoša, B. Muiesan, M.L. Mukhtorova, P. Müller-Nurasyid, M. Murphy, N. Mursu, J. Murtagh, E.M. Musa, K.I. Milanovic, S.M. Musil, V. Mustafa, N. Nabipour, I. Naderimagham, S. Nagel, G. Naidu, B.M. Najafi, F. Nakamura, H. Námešná, J. Nang, E.E.K. Nangia, V.B. Nankap, M. Narake, S. Nardone, P. Nauck, M. Neal, W.A. Nejatizadeh, A. Nekkantti, C. Nelis, K. Nelis, L. Nenko, I. Neovius, M. Nervi, F. Nguyen, C.T. Nguyen, N.D. Nguyen, Q.N. Nieto-Martínez, R.E. Nikitin, Y.P. Ning, G. Ninomiya, T. Nishtar, S. Noale, M. Noboa, O.A. Nogueira, H. Norat, T. Nordendahl, M. Nordestgaard, B.G. Noto, D. Nowak-Szczepanska, N. Al Nsour, M. Nuhoglu, I. Nurk, E. O’Neill, T.W. O’Reilly, D. Obreja, G. Ochimana, C. Ochoa-Avilés, A.M. Oda, E. Oh, K. Ohara, K. Ohlsson, C. Ohtsuka, R. Olafsson, O. Olinto, M.T.A. Oliveira, I.O. Omar, M.A. Onat, A. Ong, S.K. Ono, L.M. Ordunez, P. Ornelas, R. Ortiz, A.P. Ortiz, P.J. Osler, M. Osmond, C. Ostojic, S.M. Ostovar, A. Otero, J.A. Overvad, K. Owusu-Dabo, E. Paccaud, F.M. Padez, C. Pagkalos, I. Pahomova, E. de Paiva, K.M. Pajak, A. Palli, D. Palloni, A. Palmieri, L. Pan, W.-H. Panda-Jonas, S. Pandey, A. Panza, F. Papandreou, D. Park, S.-W. Park, S. Parnell, W.R. Parsaeian, M. Pascanu, I.M. Pasquet, P. Patel, N.D. Pecin, I. Pednekar, M.S. Peer, N. Pei, G. Peixoto, S.V. Peltonen, M. Pereira, A.C. Peres, M.A. Pérez-Farinós, N. Pérez, C.M. Peterkova, V. Peters, A. Petersmann, A. Petkeviciene, J. Petrauskiene, A. Pettenuzzo, E. Peykari, N. Pham, S.T. Pichardo, R.N. Pierannunzio, D. Pigeot, I. Pikhart, H. Pilav, A. Pilotto, L. Pistelli, F. Pitakaka, F. Piwonska, A. Pizarro, A.N. Plans-Rubió, P. Poh, B.K. Pohlabeln, H. Pop, R.M. Popovic, S.R. Porta, M. Posch, G. Poudyal, A. Poulimeneas, D. Pouraram, H. Pourfarzi, F. Pourshams, A. Poustchi, H. Pradeepa, R. Price, A.J. Price, J.F. Providencia, R. Puder, J.J. Pudule, I. Puhakka, S.E. Puiu, M. Punab, M. Qasrawi, R.F. Qorbani, M. Bao, T.Q. Radic, I. Radisauskas, R. Rahimikazerooni, S. Rahman, M. Rahman, M. Raitakari, O. Raj, M. Rakhimova, E. Rakhmatulloev, S. Rakovac, I. Rao, S.R. Ramachandran, A. Ramke, J. Ramos, E. Ramos, R. Rampal, L. Rampal, S. Rarra, V. Rascon-Pacheco, R.A. Rasmussen, M. Rech, C.R. Redon, J. Reganit, P.F.M. Regecová, V. Revilla, L. Rezaianzadeh, A. Ribas-Barba, L. Ribeiro, R. Riboli, E. Richter, A. Rigo, F. Rinaldo, N. de Wit, T.F.R. Rito, A. Ritti-Dias, R.M. Rivera, J.A. Robitaille, C. Roccaldo, R. Rodrigues, D. Rodríguez-Artalejo, F. del Cristo Rodriguez-Perez, M. Rodríguez-Villamizar, L.A. Roggenbuck, U. Rojas-Martinez, R. Rojroongwasinkul, N. Romaguera, D. Romeo, E.L. Rosario, R.V. Rosengren, A. Rouse, I. Roy, J.G.R. Rubinstein, A. Rühli, F.J. Ruidavets, J.-B. Ruiz-Betancourt, B.S. Ruiz-Castell, M. Moreno, E.R. Rusakova, I.A. Jonsson, K.R. Russo, P. Rust, P. Rutkowski, M. Sabanayagam, C. Sacchini, E. Sachdev, H.S. Sadjadi, A. Safarpour, A.R. Safiri, S. Saki, N. Salanave, B. Martinez, E.S. Salmerón, D. Salomaa, V. Salonen, J.T. Salvetti, M. Samoutian, M. Sánchez-Abanto, J. Sans, S. Marina, L.S. Santos, D.A. Santos, I.S. Santos, L.C. Santos, M.P. Santos, O. Santos, R. Sanz, S.S. Saramies, J.L. Sardinha, L.B. Sarrafzadegan, N. Sathish, T. Saum, K.-U. Savva, S. Savy, M. Sawada, N. Sbaraini, M. Scazufca, M. Schaan, B.D. Rosario, A.S. Schargrodsky, H. Schienkiewitz, A. Schipf, S. Schmidt, C.O. Schmidt, I.M. Schnohr, P. Schöttker, B. Schramm, S. Schramm, S. Schröder, H. Schultsz, C. Schutte, A.E. Sein, A.A. Selamat, R. Sember, V. Sen, A. Senbanjo, I.O. Sepanlou, S.G. Sequera, V. Serra-Majem, L. Servais, J. Ševcíková, L. Shalnova, S.A. Shamah-Levy, T. Shamshirgaran, M. Shanthirani, C.S. Sharafkhah, M. Sharma, S.K. Shaw, J.E. Shayanrad, A. Shayesteh, A.A. Shengelia, L. Shi, Z. Shibuya, K. Shimizu-Furusawa, H. Shin, D.W. Shirani, M. Shiri, R. Shrestha, N. Si-Ramlee, K. Siani, A. Siantar, R. Sibai, A.M. Silva, A.M. Silva, D.A.S. Simon, M. Simons, J. Simons, L.A. Sjöberg, A. Sjöström, M. Skodje, G. Slowikowska-Hilczer, J. Slusarczyk, P. Smeeth, L. So, H.-K. Soares, F.C. Sobek, G. Sobngwi, E. Sodemann, M. Söderberg, S. Soekatri, M.Y.E. Soemantri, A. Sofat, R. 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Zargar, A.H. Zaw, K.K. Zdrojewski, T. Zejglicova, K. Vrkic, T.Z. Zeng, Y. Zhang, L. Zhang, Z.-Y. Zhao, D. Zhao, M.-H. Zhao, W. Zhen, S. Zheng, W. Zheng, Y. Zholdin, B. Zhou, M. Zhu, D. Zins, M. Zitt, E. Zocalo, Y. Cisneros, J.Z. Zuziak, M. Ezzati, M. Filippi, S. NCD Risk Factor Collaboration (NCD-RisC)

Subjects
nutritional and metabolic diseases, sense organs, skin and connective tissue diseases
Abstract

From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. © Copyright.

Published
2021

7. Strip profile and flatness in HSM with advanced packages. (Rolling)

Author

Auzinger, D, Djumlija, G, Nijhuis, T, Seilinger, A, Widder, M, Posch, G, and Peer, L

Subjects
Voest-Alpine Industrieanlagenbau GmbH -- Product information, Construction industry -- Product information, Machinery industry -- Product information, Steel industry -- Equipment and supplies, Business, Metals, metalworking and machinery industries
Published
2003

8. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults

Author

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Subjects
SDG 3 - Good Health and Well-being, Medicine (all)
Abstract

Made available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16 Wellcome Trust AstraZeneca Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based studies with measurements of height and weight on 128.9 million participants aged 5 years and older, including 31.5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Findings Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0.01 kg/m (2) per decade; 95% credible interval -0.42 to 0.39, posterior probability [PP] of the observed decrease being a true decrease= 0.5098) in eastern Europe to an increase of 1.00 kg/m(2) per decade (0.69-1.35, PP> 0.9999) in central Latin America and an increase of 0.95 kg/m (2) per decade (0.64-1.25, PP> 0.9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0.09 kg/m(2) per decade (-0.33 to 0.49, PP= 0.6926) in eastern Europe to an increase of 0.77 kg/m (2) per decade (0.50-1.06, PP> 0.9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0.7% (0.4-1.2) in 1975 to 5.6% (4.8-6.5) in 2016 in girls, and from 0.9% (0.5-1.3) in 1975 to 7.8% (6.7-9.1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9.2% (6.0-12.9) in 1975 to 8.4% (6.8-10.1) in 2016 in girls and from 14.8% (10.4-19.5) in 1975 to 12.4% (10.3-14.5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22.7% (16.7-29.6) among girls and 30.7% (23.5-38.0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. Interpretation The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. 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Univ Gdansk, Gdansk, Poland Univ Autonoma Madrid, Madrid, Spain Univ Palermo, Palermo, Italy Pan Amer Hlth Org, Washington, DC USA Mohammed V Univ Rabat, Rabat, Morocco Univ Pernambuco, Recife, PE, Brazil Dalhousie Univ, Calgary, AB, Canada Jordan Univ Technol, Amman, Jordan Univ Fed Maranhao, Sao Luis, Brazil Univ Auckland, Auckland, New Zealand Univ Tunis El Manar, El Manar, Tunisia Fed Minist Hlth & Womens Affairs, Vienna, Austria CAFAM Univ Fdn, Bogota, Colombia Imperial Coll London, London, England Lithuanian Univ Hlth Sci, Kaunas, Lithuania Univ Sao Paulo, Sao Paulo, Brazil BJ Med Coll, Pune, Maharashtra, India Chirayu Med Coll, Bhopal, India Sunder Lal Jain Hosp, Delhi, India Shandong Univ Tradit Chinese Med, Shanghai, Peoples R China Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China Norwegian Inst Publ, Oslo, Norway Ufa Eye Res Inst, Moscow, Russia Univ Montenegro, Montenegro, Mexico Univ Southern Denmark, Lyngby, Denmark Univ Oslo, Oslo, Norway Univ Gothenburg, Gothenburg, Sweden Natl Inst Publ Hlth & Environm, Amsterdam, Netherlands Univ Turin, Turin, Italy UCL, London, England Liverpool John Moores Univ, Liverpool, Merseyside, England Nanyang Technol Univ, Singapore, Singapore German Inst Human Nutr, Hamburg, Germany Univ Republica, Montevideo, Uruguay CEMIC, La Plata, Buenos Aires, Argentina IRCCS Ist Neurol Mediterraneo Neuromed, Naples, Italy Toulouse Univ, Sch Med, Toulouse, France Univ Lausanne, Minist Hlth, Lausanne, Switzerland Flemish Agcy Care & Hlth, Brussels, Belgium Univ Ghent, Ghent, Belgium FrieslandCampina, Amersfoort, Netherlands Univ Cent Venezuela, Caracas, Venezuela Bielefeld Univ, Bielefeld, Germany WHO, Reg Off Europe, Copenhagen, Denmark German Canc Res Ctr, Heidelberg, Germany Fred Hollows Fdn New Zealand, Auckland, New Zealand Carol Davila Univ Med & Pharm, Bucharest, Romania Natl Inst Publ Hlth & Environm, Amersroot, Netherlands Univ Southern Denmark, Copenhagen, Denmark Inst Publ Hlth, Tirana, Albania Cork Inst 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Algeria Minist Salud Publ, Havana, Cuba Sahlgrens Acad, Gothenburg, Sweden Endocrinol & Met Res Ctr, Arak, Iran Indicium Res, Manila, Philippines Food & Agr Org, Rome, Italy Natl Univ Singapore, Singapore, Singapore Tampere Univ Hosp, Tampere, Finland Univ Cape Town, Cape Town, South Africa West Virginia Univ, Morgantown, WV USA Fundacao Oswaldo Cruz, Rene Rachou Res Inst, Belo Horizonte, MG, Brazil Natl Taiwan Univ, Taipei, Taiwan Univ Chinese Acad Sci, Beijing, Peoples R China Uppsala Univ, Uppsala, Sweden Capital Med Univ, Beijing An Zhen Hosp, Beijing, Peoples R China Natl Inst Hlth Dev, Tallinn, Estonia Univ Med Greifswald, Greifswald, Germany Consejeria Sanidad Junta Castilla & Leon, Valladolid, Spain Univ Fed Ouro Pret, Ouro Preto, Brazil Jikei Univ, Sch Med, Tokyo, Japan CNR, Rome, Italy Baker Heart & Diabet Inst, Melbourne, Vic, Australia Agr Univ Athens, Athens, Greece Univ Putra Malaysia, Seri Kembangan, Malaysia Inst Rech Dev, Marseille, France Hosp Israelita Albert 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Fdn, Athens, Greece Univ Pharm & Med Ho Chi Min City, Ho Chi Minh, Vietnam Governm Med Coll, Secunderabad, India Sefako Makgatho Hlth Sci Univ, Kangnung, South Korea Addis Ababa Univ, Addis Ababa, Ethiopia Dasman Diabet Inst, Kuwait, Kuwait Minist Hlth, Thorndon, New Zealand Hellen Med Associat Obes, Athens, Greece Univ Ctr Occidental Lisandro Alvarado, Barquisimeto, Venezuela Meharry Med Coll, Nashville, TN USA Dokuz Eylul Univ, Izmir, Turkey Univ Tampere, Tays Eye Ctr, Tampere, Finland Polytech Inst Porto, Oporto, Portugal Univ Utrecht, Utrecht, Netherlands Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands Fed Univ Pelota, Pelotas, Brazil Italian Natl Res Council, Rome, Italy Univ Miguel Hernandez, Elche, Spain Minist Hlth, Victoria, Seychelles North Karelian Ctr Publ Hlth, Joensuu, Finland ISGlobal Ctr Res Environm Epidemiol, Barcelona, Spain Univ Witwatersrand, Johannesburg, South Africa Med Univ Vienna, Vienna, Austria Univ Coll Cork, Cork, Ireland Inst Med Res, Kuala Lumpur, Malaysia Xinjiang Med Univ, Urumqi, Peoples R China St Georges Univ London, London, England Univ Indonesia, Depok, Indonesia Natl Inst Hyg, Warsaw, Poland Caja Costarricense Seguro Social, Atenas, Costa Rica Univ Kebangsaan Malaysia, Bangi Selangor, Malaysia Univ New South Wales, Kensington, NSW, Australia Univ Mancheste, Manchester, Lancs, England Shandong Univ Tradit Chinese Med, Jinan, Shandong, Peoples R China Kailuan Gen Hosp, Tangshan, Peoples R China Minist Agr, Inst Food & Dev, Beijing, Peoples R China Fudan Univ, Childrens Hosp, Shanghai, Peoples R China Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China Univ Cyprus, Nicosia, Cyprus Univ Teknol MARA, Shah Alam, Malaysia Capital Med Univ Beijing, An Zhen Hosp, Beijing, Peoples R China West Kazakhstan State Med Univ, Aktobe, Kazakhstan Inner Mongolia Med Univ, Hohhot, Peoples R China Gorgas Mem Inst Publ Hlth, Panama City, Panama Univ Estadual Paulista, Sao Paulo, Brazil

Published
2017

9. Suitability of high alloyed wire electrodes for the positional laser-GMA-hybrid welding

Author

Lorenz, S., Kannengiesser, T., Herold, H., and Posch, G.

Subjects
Electrodes -- Analysis, Gas metal arc welding -- Analysis, Wire -- Properties, Wire -- Analysis, High technology industry
Abstract

Byline: S. Lorenz, T. Kannengiesser, H. Herold, G. Posch Laser-gas metal arc (GMA)-hybrid welding enables a high deposition rate and a stable welding process. Process stability was found to be profoundly dependent on the type of the applied filler wire (solid or tubular cored). Whereas solid wires are deposited in pulsed arc mode, tubular cored wire electrodes are weldable by a stable spray-arc process within a wide operating range. This fact applies above all to a high alloyed metal cored wire electrode, of which the achievable deposition rates exceed the upper limits recommended by the manufacturer. A further interesting aspect is the application of a rutile tubular cored wire for positional laser-GMA-hybrid welding. A modern 20 kW-fibre laser source was available for the experiments. This study is concerned with the weldability of high alloyed tubular cored electrodes for high power laser-GMA-hybrid welding. Results obtained from comparative investigations between tubular cored and solid wire electrodes relating to process stability are summarised.

Published
2010

10. Reproduce diameter reduction process of a powder filled tube in finite element analysis

Author

Böck, B., Buchmayr, B., Wallner, S., and Posch, G.

Subjects
Finite element method, Plasticity, Plasticity -- Mathematical models, Plasticitat, Elements finits, Mètode dels, Matemàtiques i estadística::Anàlisi numèrica::Mètodes en elements finits [Àrees temàtiques de la UPC], Roll Drawing, Reduction of a tube with powder filling, Powder Compaction, Plasticitat -- Models matemàtics
Abstract

Aim of the present work is to improve the production of laserwelded flux cored wires with the help of Finite Element Analysis in Abaqus. This flux cored wires are used as welding consumables. To simulate the whole production process for every variety of input parameters is far too time-consuming particularly with regard to the filling. The production process is as following: after roll forming of a strip to a U-shape it is filled continuously with flux. This powder consists of up to 20 different substances. Afterwards the profile is closed to a tube and the edge is laserwelded. At last the diameter of the tube is reduced to 1.2 mm. The reduction step is investigated and subject of the present work. Observations have shown the most abrasion of the working dies in reduction steps where it is not expected due to the calculated true strain sequence. Therefore, the influence of the filling on the roll drawing process has to be taken into account. This is not easy because the process starts with loose multicomponent powder and ends with high compaction. It is hard to cover these demands with a single model for powder behaviour. So a phenomenological approach is established to solve the problem. The influence of the powder is described as a load which only appears in the projected contact area. Consequently, it becomes possible to study parameters on the reduction like different quantities of the multicomponent powder, the reduction sequence of the roll drawing process and the geometry of the rolls.

Published
2011

19. ADVANCED GAS TUNGSTEN ARC WELDING (SURFACING) CURRENT STATUS AND APPLICATION.

Author

EGERLAND, S., ZIMMER, J., BRUNMAIER, R., NUSSBAUMER, R., POSCH, G., and RUTZINGER, B.

Subjects
ELECTRIC welding, METAL cladding, ELECTROSLAG process
Abstract

Gas Shielded Tungsten Arc Welding (GTAW) -- a process well-known providing highest quality weld results joined though by lower performance. Gas metal arc welding is frequently chosen to increase productivity along with broadly accepted quality. Those industry segments, especially required to produce high quality corrosion-resistant surfacing, e.g. applying nickel-based filler materials, are regularly in consistent demand to comply with «zero defect» criteria. In this conjunction weld performance limitations are overcome employing advanced «hot-wire» GTAW systems. This paper, from a welding automation perspective, describes the technology of such devices and deals with the current status is this field, namely the application of dual-cathode hot-wire electrode GTAW cladding, considerably broadening achievable limits. 27 Ref., 2 Tables, 14 Figures. [ABSTRACT FROM AUTHOR]

Published
2016
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21. Welding of railway wagons: tasks in the area of materials, processes and automation.

Author

Posch, G., Holtsinger, V., and Bychkovskii, S.L.

Subjects
WELDED joints, WAGONS, ELECTRIC welding automation, RAILROADS, HEAT treatment, WELDING defects, VEHICLE design & construction
Abstract

The key points of current trends in the development of materials and the latest achievements in the area of welding technology are discussed. Special attention is given to increasing the quality of welded joints and reducing the level of welding strains by minimizing the heat input. A number of methods of welding railway wagons, developed by Fronius International GmbH, are described. [ABSTRACT FROM AUTHOR]

Published
2015
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22. Welding advanced martensitic creep-resistant steels with boron containing filler metal.

Author

Baumgartner, S., Posch, G., and Mayr, P.

Subjects
*ALLOYS, *WELDING research, *WELDED joints, *MECHANICAL behavior of materials, *BORON, *FOUNDING, *CASTING (Manufacturing process)
Abstract

Within the last years, the beneficial effect of boron addition in order to increase the creep strength of martensitic 9-12 % Cr steels has been widely investigated and demonstrated. Several boron-strengthened alloys are the outcome of an intensive European research activity within the scientific framework of COST. Tire most promising alloy for castings with a targeted application temperature of 650 °C for use in future ultra-super critical steam power plants is a modified 0.1C-9Cr-1.5Mo steel with the addition of approximately 110 ppm boron. For joining of this advanced steel grade, new "chemically matching" welding consumables have to be developed to provide similar creep strength in the weld. Within this paper, the development of an advanced flux-cored wire with a good "out of position weldability" - based on a rutile slag system is presented. The work discusses the optimization of the chemical composition of the filler, the influence of various post-weld heat treatments on short term mechanical properties, first results of creep tests and results of thick section welds. The boron content of the consumable was optimized to achieve highest creep strength combined with acceptable toughness and lowest hot cracking sensitivity. For a butt weld of a 34 mm-thick casting, the optimum welding parameters and layer sequence were determined. A post-weld heat treatment consisting of stress relieving twice at 730 °C for 12 h seemed to be the best compromise between applicability in the manufacturing of large turbine casings and achievement of acceptable weld toughness. [ABSTRACT FROM AUTHOR]

Published
2014

23. Potential of the Tannerella forsythia S-layer to Delay the Immune Response.

Author

Sekot, G., Posch, G., Messner, P., Matejka, M., Rausch-Fan, X., Andrukhov, O., and Schäffer, C.

Subjects
IMMUNE response, BACTERIA, IMMUNOLOGY, CYTOKINES, MACROPHAGES, FIBROBLASTS, INFLAMMATION, MICROBIAL virulence, CELL lines, POLYMERASE chain reaction, MESSENGER RNA, ELECTRON microscopy
Abstract

The periodontal pathogen Tannerella forsythia possesses a glycosylated S-layer as an outermost cell decoration. While the S-layer provides a selection advantage to the bacterium in the natural habitat, its virulence potential remains to be investigated. In the present study, the immune responses of human macrophages and gingival fibroblasts upon stimulation with wild-type T. forsythia and an S-layer-deficient mutant were investigated. The mRNA expression levels of the pro-inflammatory mediators IL-1β, TNF-α, and IL-8 were analyzed by qPCR, and the production of the corresponding cytokines was investigated by ELISA. The S-layer-deficient T. forsythia mutant induced significantly higher levels of pro-inflammatory mediators compared with wild-type T. forsythia, especially at the early phase of response. Analysis of these data suggests that the S-layer of T. forsythia is an important virulence factor that attenuates the host immune response to this pathogen by evading the bacterium’s recognition by the innate immune system. Abbreviations: DMSO, dimethylsulfoxide; FBS, fetal bovine serum; GAPDH, glycerinaldehyde-3-phosphate-dehydrogenase; HGFs, human gingival fibroblasts; LPS, lipopolysaccharide; MEM, minimal essential medium; MTT, 3,4,5-dimethylthiazol-2-yl-2,5-diphenyl tetrazolium bromide; OD, optical density; PBS, phosphate-buffered saline; qPCR, quantitative polymerase chain-reaction; SD, standard deviation; Tannerella forsythia ATCC 43037, Tf wt; Tannerella forsythia ATCC 43037 S-layer mutant, Tf ΔtfsAB. [ABSTRACT FROM PUBLISHER]

Published
2011
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27. Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants

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Male, body-mass index, ADULTHOOD, Adolescents, pituuskasvu, Pediatrics, Body Mass Index, 0302 clinical medicine, Child Development, nuoret, Public health surveillance, Medicine, Health Status Indicators, 10. No inequality, Child, 11 Medical and Health Sciences, Body mass index, ComputingMilieux_MISCELLANEOUS, education.field_of_study, VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801, General Medicine, Body mass indexes, kansainvälinen vertailu, 3. Good health, Geography, Health, 030220 oncology & carcinogenesis, Child, Preschool, Medical and Health sciences, purl.org/becyt/ford/3 [https], medicine.medical_specialty, School-aged adolescents, Socio-culturale, lapset (ikäryhmät), Nursing, territories, ravinto, purl.org/becyt/ford/3.3 [https], 03 medical and health sciences, School Children, SDG 3 - Good Health and Well-being, SYSTEMATIC ANALYSIS, Humans, school-aged children and adolescents, Montenegro, education, Science & Technology, Omvårdnad, Health sciences, Medical and Health sciences, Ciências médicas e da saúde, Bayes Theorem, Anthropometry, Adolescent Development, medicine.disease, TRENDS, Height and Body-mass Index, Faculdade de Ciências Sociais, UNDERNUTRITION, Height index trajectories, Height, body mass index, children , epidemiology, risk factors, growth, Stature, Demography, Settore MED/09 - Medicina Interna, Internationality, [SDV]Life Sciences [q-bio], 030204 cardiovascular system & hematology, Body-mass index trajectories, Epidemiology, Medicine and Health Sciences, risk factors, countries, EPIDEMIOLOGY, height, children, adolescents, BMI, 030212 general & internal medicine, painoindeksi, Child development, 2. Zero hunger, Medicine(all), School age child, obestity children cardiovascular, Population Health, 1. No poverty, Pediatrik, Public Health, Global Health, Social Medicine and Epidemiology, 3142 Public health care science, environmental and occupational health, Pooled analysis, NUTRITION, Female, medicine.symptom, pooled analysis, Life Sciences & Biomedicine, terveys, height, BMI, nutrition, health, children, adolescents, Adolescent, growth, Population, body-mass, Population based, Body-mass index, Young Adult, Medicine, General & Internal, Meta-Analysis as Topic, General & Internal Medicine, parasitic diseases, Weight gain, School-aged childrens, Age trajectories, business.industry, Height, Weight, Body Height, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Malnutrition, ONSET, Ciências da Saúde, Ciências médicas e da saúde, School-aged children, VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801, business, terveysriskit, Estilos de Vida e Impacto na Saúde
Abstract

BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents., METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a Bayesian hierarchical model to estimate trends from 1985 to 2019 in mean height and mean BMI in 1-year age groups for ages 5–19 years. The model allowed for non-linear changes over time in mean height and mean BMI and for non-linear changes with age of children and adolescents, including periods of rapid growth during adolescence., FINDINGS: We pooled data from 2181 population-based studies, with measurements of height and weight in 65 million participants in 200 countries and territories. In 2019, we estimated a difference of 20 cm or higher in mean height of 19-year-old adolescents between countries with the tallest populations (the Netherlands, Montenegro, Estonia, and Bosnia and Herzegovina for boys; and the Netherlands, Montenegro, Denmark, and Iceland for girls) and those with the shortest populations (Timor-Leste, Laos, Solomon Islands, and Papua New Guinea for boys; and Guatemala, Bangladesh, Nepal, and Timor-Leste for girls). In the same year, the difference between the highest mean BMI (in Pacific island countries, Kuwait, Bahrain, The Bahamas, Chile, the USA, and New Zealand for both boys and girls and in South Africa for girls) and lowest mean BMI (in India, Bangladesh, Timor-Leste, Ethiopia, and Chad for boys and girls; and in Japan and Romania for girls) was approximately 9–10 kg/m2. In some countries, children aged 5 years started with healthier height or BMI than the global median and, in some cases, as healthy as the best performing countries, but they became progressively less healthy compared with their comparators as they grew older by not growing as tall (eg, boys in Austria and Barbados, and girls in Belgium and Puerto Rico) or gaining too much weight for their height (eg, girls and boys in Kuwait, Bahrain, Fiji, Jamaica, and Mexico; and girls in South Africa and New Zealand). In other countries, growing children overtook the height of their comparators (eg, Latvia, Czech Republic, Morocco, and Iran) or curbed their weight gain (eg, Italy, France, and Croatia) in late childhood and adolescence. When changes in both height and BMI were considered, girls in South Korea, Vietnam, Saudi Arabia, Turkey, and some central Asian countries (eg, Armenia and Azerbaijan), and boys in central and western Europe (eg, Portugal, Denmark, Poland, and Montenegro) had the healthiest changes in anthropometric status over the past 3·5 decades because, compared with children and adolescents in other countries, they had a much larger gain in height than they did in BMI. The unhealthiest changes—gaining too little height, too much weight for their height compared with children in other countries, or both—occurred in many countries in sub-Saharan Africa, New Zealand, and the USA for boys and girls; in Malaysia and some Pacific island nations for boys; and in Mexico for girls., INTERPRETATION: The height and BMI trajectories over age and time of school-aged children and adolescents are highly variable across countries, which indicates heterogeneous nutritional quality and lifelong health advantages and risks., Wellcome Trust, AstraZeneca Young Health Programme, EU., peer-reviewed

Published
2020
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28. Rising rural body-mass index is the main driver of the global obesity epidemic in adults

Author

Bixby, Honor, Bentham, James, Zhou, Bin, Di Cesare, Mariachiara, Paciorek, Christopher J., Bennett, James E., Taddei, Cristina, Stevens, Gretchen A., Rodriguez-Martinez, Andrea, Carrillo-Larco, Rodrigo M., Khang, Young-Ho, Soric, Maroje, Gregg, Edward W., Miranda, J. Jaime, Bhutta, Zulfiqar A., Savin, Stefan, Sophiea, Marisa K., Iurilli, Maria L. C., Solomon, Bethlehem D., Cowan, Melanie J., Riley, Leanne M., Danaei, Goodarz, Bovet, Pascal, Chirita-Emandi, Adela, Hambleton, Ian R., Hayes, Alison J., Ikeda, Nayu, Kengne, Andre P., Laxmaiah, Avula, Li, Yanping, McGarvey, Stephen T., Mostafa, Aya, Neovius, Martin, Starc, Gregor, Zainuddin, Ahmad A., Abarca-Gomez, Leandra, Abdeen, Ziad A., Abdrakhmanova, Shynar, Ghaffar, Suhaila Abdul, Hamid, Zargar Abdul, Garba, Jamila Abubakar, Abu-Rmeileh, Niveen M., Acosta-Cazares, Benjamin, Adams, Robert J., Aekplakorn, Wichai, Afsana, Kaosar, Agdeppa, Imelda A., Aguilar-Salinas, Carlos A., Agyemang, Charles, Ahmad, Mohamad Hasnan, Ahmad, Noor Ani, Ahmadi, Naser, Ahmadvand, Alireza, Ahrens, Wolfgang, Ajlouni, Kamel, AlBuhairan, Fadia, AlDhukair, Shahla, Al-Hazzaa, Hazzaa M., Ali, Mohamed M., Ali, Osman, Alkerwi, Ala'a, Al-Othman, Amani Rashed, Al-Raddadi, Rajaa, Alvarez-Pedrerol, Mar, Aly, Eman, Amarapurkar, Deepak N., Amouyel, Philippe, Amuzu, Antoinette, Bo, Lars, Anderssen, Sigmund A., Angquist, Lars H., Anjana, Ranjit Mohan, Ansari-Moghaddam, Alireza, Aounallah-Skhiri, Hajer, Araujo, Joana, Ariansen, Inger, Aris, Tahir, Arku, Raphael E., Arlappa, Nimmathota, Aryal, Krishna K., Aspelund, Thor, Assah, Felix K., Assuncao, Maria Cecilia F., Aung, May Soe, Auvinen, Juha, Avdicova, Maria, Azevedo, Ana, Azizi, Fereidoun, Azmin, Mehrdad, Babu, Bontha V., Baharudin, Azli, Bahijri, Suhad, Baker, Jennifer L., Balakrishna, Nagalla, Bamoshmoosh, Mohamed, Banach, Maciej, Bandosz, Piotr, Banegas, Jose R., Barbagallo, Carlo M., Barcelo, Alberto, Barkat, Amina, Barros, Aluisio J. D., Barros, Mauro V. G., Bata, Iqbal, Batieha, Anwar M., Batista, Rosangela L., Battakova, Zhamilya, Batyrbek, Assembekov, Baur, Louise A., Beaglehole, Robert, Bel-Serrat, Silvia, Ben Romdhane, Habiba, Benedics, Judith, Benet, Mikhail, Berkinbayev, Salim, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K., Bi, Hongsheng, Bi, Yufang, Biehl, Anna, Lele, Elysee Claude Bika, Bikbov, Mukharram, Bista, Bihungum, Bjelica, Dusko J., Bjerregaard, Peter, Bjertness, Espen, Bjertness, Marius B., Bjorkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boddy, Lynne M., Boehm, Bernhard O., Boeing, Heiner, Boggia, Jose G., Boissonnet, Carlos P., Bonaccio, Marialaura, Bongard, Vanina, Bopp, Matthias, Borchini, Rossana, Borghs, Herman, Braeckevelt, Lien, Braeckman, Lutgart, Bragt, Marjolijn C. E., Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Breda, Joao, Brenner, Hermann, Brewster, Lizzy M., Brian, Garry R., Brinduse, Lacramioara, Bruno, Graziella, Bueno-de-Mesquita, H. Bas, Bugge, Anna, Buoncristiano, Marta, Burazeri, Genc, Burns, Con, Cabrera de Leon, Antonio, Cacciottolo, Joseph, Cai, Hui, Cama, Tilema, Cameron, Christine, Camolas, Jose, Can, Gamze, Can, Gunay, Candido, Ana Paula C., Canete, Felicia, Capanzana, Mario V., Capuano, Eduardo, Capuano, Vincenzo, Cardoso, Viviane C., Carlsson, Axel C., Carmuega, Esteban, Carvalho, Maria J., Casanueva, Felipe F., Casas, Juan-Pablo, Caserta, Carmelo A., Celikcan, Ertugrul, Censi, Laura, Cesar, Juraci A., Chamukuttan, Snehalatha, Chan, Angelique W., Chan, Queenie, Chaturvedi, Himanshu K., Chaturvedi, Nishi, Rahim, Norsyamlina Che Abdul, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Cheng, Yiling J., Chetrit, Angela, Chikova-Iscener, Ekaterina, Chiolero, Arnaud, Chiou, Shu-Ti, Chirlaque, Maria-Dolores, Cho, Belong, Cho, Yumi, Christensen, Kaare, Christofaro, Diego G., Chudek, Jerzy, Cifkova, Renata, Cilia, Michelle, Cinteza, Eliza, Claessens, Frank, Clarke, Janine, Clays, Els, Concin, Hans, Confortin, Susana C., Cooper, Cyrus, Coppinger, Tara C., Costanzo, Simona, Cottel, Dominique, Cowell, Chris, Craig, Cora L., Crampin, Amelia C., Crujeiras, Ana B., Cruz, Juan J., Cucu, Alexandra, Cui, Liufu, Dallongeville, Jean, Damasceno, Albertino, Damsgaard, Camilla T., Dankner, Rachel, Dantoft, Thomas M., D'Arrigo, Graziella, Dasgupta, Parasmani, Dastgiri, Saeed, Dauchet, Luc, Davletov, Kairat, De Backer, Guy, De Bacquer, Dirk, De Curtis, Amalia, de Gaetano, Giovanni, De Henauw, Stefaan, de Oliveira, Paula Duarte, De Ridder, Karin, de Rooij, Susanne R., De Smedt, Delphine, Deepa, Mohan, Deev, Alexander D., Dehghan, Abbas, Delisle, Helene, Delpeuch, Francis, Dennison, Elaine, Deschamps, Valerie, Dhana, Klodian, Dhimal, Meghnath, Di Castelnuovo, Augusto F., Dias-da-Costa, Juvenal Soares, Diaz, Alejandro, Dika, Zivka, Djalalinia, Shirin, Do, Ha T. 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H, Zapata ME, Zaw KK, Zdrojewski T, Zeljkovic Vrkic T, Zeng Y, Zhao D, Zhao W, Zheng W, Zheng Y, Zholdin B, Zhou M, Zhu D, Zhussupov B, Zimmermann E, Zuñiga Cisneros J, Ezzati M, Yiallouros, Panayiotis K. [0000-0002-8339-9285], APH - Societal Participation & Health, APH - Aging & Later Life, Epidemiology and Data Science, Public and occupational health, APH - Health Behaviors & Chronic Diseases, and APH - Personalized Medicine

Subjects
Male, Rural Population, obesity, Obesity, body mass index, Settore MED/09 - Medicina Interna, Letter, Urban Population, Epidemiology, [SDV]Life Sciences [q-bio], humanos, body-mass index, adolescente, Geographic Mapping, Sex Factor, países desarrollados, Rural Health, purl.org/pe-repo/ocde/ford#3.03.09 [https], systematic analysis, Body Mass Index, países en desarrollo, 80 and over, risk factors, Age Factor, physical-activity, mediana edad, mapeo geográfico, Aged, 80 and over, anciano, purl.org/pe-repo/ocde/ford#3.02.18 [https], dieta, Age Factors, health, adulto, Middle Aged, Multidisciplinary Sciences, adulto joven, [SDV] Life Sciences [q-bio], estado nutricional, nutrition, Science & Technology - Other Topics, NUTRITION, Female, HEALTH, pooled analysis, Diet, Healthy, worldwide trends, Human, Developed Countrie, Adult, Adolescent, purl.org/pe-repo/ocde/ford#3.03.04 [https], FOOD SYSTEM, Socio-culturale, Nutritional Status, URBAN, Aged, Developed Countries, Developing Countries, Humans, Obesity, Sex Factors, Urban Health, Young Adult, POOLED ANALYSIS, Developing Countrie, MIDDLE-INCOME COUNTRIES, SYSTEMATIC ANALYSIS, Urban rural Obesity Body-Mass-Index, obesidad, Middle-income countries, food system, urban, weight, Healthy, Science & Technology, índice de masa corporal, Diet, PHYSICAL-ACTIVITY, WORLDWIDE TRENDS, Risk factors, [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, WEIGHT
Abstract

Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities(.)(1,2) This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity(3-6). Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean BMI segregated by place of residence (a rural or urban area) from 1985 to 2017. We show that, contrary to the dominant paradigm, more than 55% of the global rise in mean BMI from 1985 to 2017-and more than 80% in some low- and middle-income regions-was due to increases in BMI in rural areas. This large contribution stems from the fact that, with the exception of women in sub-Saharan Africa, BMI is increasing at the same rate or faster in rural areas than in cities in low- and middle-income regions. These trends have in turn resulted in a closing-and in some countries reversal-of the gap in BMI between urban and rural areas in low- and middle-income countries, especially for women. In high-income and industrialized countries, we noted a persistently higher rural BMI, especially for women. There is an urgent need for an integrated approach to rural nutrition that enhances financial and physical access to healthy foods, to avoid replacing the rural undernutrition disadvantage in poor countries with a more general malnutrition disadvantage that entails excessive consumption of low-quality calories., This study was funded by the Wellcome Trust. H.B. was supported by a Medical Research Council Doctoral Training Partnership Studentship, J.B. by a Royal Society Research Grant, and M.D.C. by an Academy of Medical Sciences Springboard Award. We thank L. Jaacks, B. Popkin, S. Sundberg and W. Willett for recommendations of relevant citations. The authors are responsible for the views expressed in this Letter and they do not necessarily represent the views, decisions, or policies of the institutions with which they are affiliated.

Published
2019
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29. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

Author

NCD Risk Factor Collaboration (NCD-RisC), Abarca-Gómez, L., Abdeen, Z.A., Hamid, Z.A., Abu-Rmeileh, N.M., Acosta-Cazares, B., Acuin, C., Adams, R.J., Aekplakorn, W., Afsana, K., Aguilar-Salinas, C.A., Agyemang, C., Ahmadvand, A., Ahrens, W., Ajlouni, K., Akhtaeva, N., Al-Hazzaa, H.M., Al-Othman, A.R., Al-Raddadi, R., Al Buhairan, F., Al Dhukair, S., Ali, M.M., Ali, O., Alkerwi, A., Alvarez-Pedrerol, M., Aly, E., Amarapurkar, D.N., Amouyel, P., Amuzu, A., Andersen, L.B., Anderssen, S.A., Andrade, D.S., Ängquist, L.H., Anjana, R.M., Aounallah-Skhiri, H., Araújo, J., Ariansen, I., Aris, T., Arlappa, N., Arveiler, D., Aryal, K.K., Aspelund, T., Assah, F.K., Assunção, MCF, Aung, M.S., Avdicová, M., Azevedo, A., Azizi, F., Babu, B.V., Bahijri, S., Baker, J.L., Balakrishna, N., Bamoshmoosh, M., Banach, M., Bandosz, P., Banegas, J.R., Barbagallo, C.M., Barceló, A., Barkat, A., Barros, A.J., Barros, M.V., Bata, I., Batieha, A.M., Batista, R.L., Batyrbek, A., Baur, L.A., Beaglehole, R., Romdhane, H.B., Benedics, J., Benet, M., Bennett, J.E., Bernabe-Ortiz, A., Bernotiene, G., Bettiol, H., Bhagyalaxmi, A., Bharadwaj, S., Bhargava, S.K., Bhatti, Z., Bhutta, Z.A., Bi, H., Bi, Y., Biehl, A., Bikbov, M., Bista, B., Bjelica, D.J., Bjerregaard, P., Bjertness, E., Bjertness, M.B., Björkelund, C., Blokstra, A., Bo, S., Bobak, M., Boddy, L.M., Boehm, B.O., Boeing, H., Boggia, J.G., Boissonnet, C.P., Bonaccio, M., Bongard, V., Bovet, P., Braeckevelt, L., Braeckman, L., Bragt, M.C., Brajkovich, I., Branca, F., Breckenkamp, J., Breda, J., Brenner, H., Brewster, L.M., Brian, G.R., Brinduse, L., Bruno, G., Bueno-de-Mesquita, HBA, Bugge, A., Buoncristiano, M., Burazeri, G., Burns, C., de León, A.C., Cacciottolo, J., Cai, H., Cama, T., Cameron, C., Camolas, J., Can, G., Cândido, APC, Capanzana, M., Capuano, V., Cardoso, V.C., Carlsson, A.C., Carvalho, M.J., Casanueva, F.F., Casas, J.P., Caserta, C.A., Chamukuttan, S., Chan, A.W., Chan, Q., Chaturvedi, H.K., Chaturvedi, N., Chen, C.J., Chen, F., Chen, H., Chen, S., Chen, Z., Cheng, C.Y., Chetrit, A., Chikova-Iscener, E., Chiolero, A., Chiou, S.T., Chirita-Emandi, A., Chirlaque, M.D., Cho, B., Cho, Y., Christensen, K., Christofaro, D.G., Chudek, J., Cifkova, R., Cinteza, E., Claessens, F., Clays, E., Concin, H., Confortin, S.C., Cooper, C., Cooper, R., Coppinger, T.C., Costanzo, S., Cottel, D., Cowell, C., Craig, C.L., Crujeiras, A.B., Cucu, A., D'Arrigo, G., d'Orsi, E., Dallongeville, J., Damasceno, A., Damsgaard, C.T., Danaei, G., Dankner, R., Dantoft, T.M., Dastgiri, S., Dauchet, L., Davletov, K., De Backer, G., De Bacquer, D., De Curtis, A., de Gaetano, G., De Henauw, S., de Oliveira, P.D., De Ridder, K., De Smedt, D., Deepa, M., Deev, A.D., Dehghan, A., Delisle, H., Delpeuch, F., Deschamps, V., Dhana, K., Di Castelnuovo, A.F., Dias-da-Costa, J.S., Diaz, A., Dika, Z., Djalalinia, S., Do, H.T., Dobson, A.J., Donati, M.B., Donfrancesco, C., Donoso, S.P., Döring, A., Dorobantu, M., Dorosty, A.R., Doua, K., Drygas, 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Abstract

Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants aged 5 years and older, including 31·5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0·01 kg/m2 per decade; 95% credible interval -0·42 to 0·39, posterior probability [PP] of the observed decrease being a true decrease=0·5098) in eastern Europe to an increase of 1·00 kg/m2 per decade (0·69-1·35, PP>0·9999) in central Latin America and an increase of 0·95 kg/m2 per decade (0·64-1·25, PP>0·9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0·09 kg/m2 per decade (-0·33 to 0·49, PP=0·6926) in eastern Europe to an increase of 0·77 kg/m2 per decade (0·50-1·06, PP>0·9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0·7% (0·4-1·2) in 1975 to 5·6% (4·8-6·5) in 2016 in girls, and from 0·9% (0·5-1·3) in 1975 to 7·8% (6·7-9·1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9·2% (6·0-12·9) in 1975 to 8·4% (6·8-10·1) in 2016 in girls and from 14·8% (10·4-19·5) in 1975 to 12·4% (10·3-14·5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22·7% (16·7-29·6) among girls and 30·7% (23·5-38·0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. Wellcome Trust, AstraZeneca Young Health Programme.

Published
2017

30. Search for diphoton events with large missing transverse energy in 7 TeV proton-proton collisions with the ATLAS detector

Author

N. Davidson, M. Uslenghi, Laurent Vacavant, M. Bendel, D. Schouten, J. Cammin, Gideon Bella, P. F. Zema, Wendy Taylor, Giancarlo Spigo, J. Meinhardt, R. Beccherle, Kathleen Whalen, S. Owen, Michel Lefebvre, Marcos Vinicius Silva Oliveira, D. Fassouliotis, Ralf Hertenberger, S. M. Fisher, Paul Laycock, Irakli Minashvili, A. A. Abdelalim, Corrinne Mills, Tapas Sarangi, A. Staude, Danuta Kisielewska, H. J. Burckhart, R. Dankers, Konstantin Toms, Yuri Kulchitsky, Vadim Gratchev, Si Xie, Jacqueline Batley, Manuela Venturi, Xuai Zhuang, Samira Hassani, Nikolai Rusakovich, C. J. Curtis, Gabriele Chiodini, Phillip Allport, Carlo Schiavi, Allan G Clark, Roger Moore, Anna Macchiolo, Kerstin Tackmann, E. Williams, S. Willocq, Marco Fraternali, Thibault Guillemin, C. Da Via, Stefanie Adomeit, S. Mättig, J. Farley, Kevin Varvell, V. Kral, V. A. Gapienko, G. S. Huang, M. Ibbotson, D. Su, J. T. Childers, Evgeniy Khramov, A. Ferretto Parodi, Ole Røhne, Frank Siegert, Judith Katzy, Fred Hartjes, N. D. Brett, S. De Castro, Ian Brock, G. Polesello, Vincent Hedberg, Jan Valenta, D. Traynor, M. Petteni, Yasuyuki Okumura, William Quayle, N. Skvorodnev, Y. B. Pan, O. G. Grebenyuk, Helio Takai, S. Hamilton, Yang Yang, M. Terwort, Massimo Sorbi, J. Garvey, Hans Krüger, William Brooks, M. C. Tamsett, D. Harper, M. Rescigno, V. Chernyatin, M. P. Sanders, Mous Tatarkhanov, Rashid M. Djilkibaev, Hyun-Chul Kim, Bengt Lund-Jensen, Benjamin Kaplan, Jun Wakabayashi, Lidia Smirnova, R. Kowalewski, Yaquan Fang, F. Wicek, Lukasz Zwalinski, Kirill Prokofiev, A. Palma, Reiner Hauser, S. Cuneo, Bruce Gallop, Laurent Chevalier, Tetiana Hryn'ova, Peter Hansen, Hantao Ji, J. D. Dowell, David Berge, N. De Groot, D. Roda Dos Santos, R. E. Hughes-Jones, Hiroshi Sakamoto, J. Petersen, Peter Kodys, Andreas W. W. Ludwig, Charles Taylor, C. Benchouk, M. Karnevskiy, L. Rosselet, M. Cambiaghi, Susumu Oda, A. Pickford, Shuang-Lin Li, O. B. Dogan, B. Sopko, A. I. Kononov, Gordon Watts, Fabienne Ledroit-Guillon, Kyle Cranmer, Claudio Ferretti, Aaron Angerami, J. Lundquist, R. Perrino, Tohru Takeshita, P. J. Clark, Bellisario Esposito, E. Cogneras, Vadim Kantserov, M. Hauschild, N. Boelaert, A. Kocnar, Alejandro Alonso, Mustafa Yilmaz, J. P. Archambault, S. Walch, Giovanni Darbo, K. Nagai, Iskander Ibragimov, Klaus Hamacher, M. D. Ciobotaru, B. Guo, Valerio Dao, Peter Buchholz, G. A. Odino, T. Perez Cavalcanti, Jian Wang, L. Rumyantsev, J. W. Schumacher, Marianna Testa, P. N. Ratoff, B. Auerbach, Tatiana Klioutchnikova, Dilip Jana, R. K. Bock, Stefan Valkar, Rostislav Konoplich, M. Lungwitz, Graeme Stewart, Zdenek Dolezal, J. E. García Navarro, Kerstin Jon-And, L. Xaplanteris, G. Cataldi, M. Sosebee, Jacob Searcy, Massimiliano Bellomo, Borut Paul Kerševan, Arthur Moraes, Barbara Wosiek, D. Joffe, J. Z. Will, Uwe Bratzler, Pierre-Antoine Delsart, S. Vallecorsa, K. Fowler, A. Papadelis, Tancredi Carli, T. Stahl, K. Stevenson, Roberto Cardarelli, Mark Sutton, José Salt, S. Nelson, Abdeslam Hoummada, D. H. Saxon, Laura Jeanty, T. Buran, Markus Elsing, Lee Sawyer, Sally Seidel, Peter Onyisi, Mattias Ellert, M. Losada, Filippo Maria Giorgi, P. M. Tuts, T. Ohsugi, K. H. Hiller, K. Mahboubi, J. Silva, Kiyotomo Kawagoe, Jean-Francois Arguin, D. Urbaniec, A. Vogel, Veysi Erkcan Ozcan, Andreas Petridis, Gianluca Alimonti, Rainer Stamen, T. B. Sjursen, G. Hughes, Urmila Soldevila, Alberto Mengarelli, P. D. Thompson, C. Carpentieri, S. Swedish, M. S. Kayl, M. Kurata, M. Schmitz, Patrick Fassnacht, I. Ludwig, Andrew Pilkington, Christos Anastopoulos, Bianca Osculati, Bobby Samir Acharya, H. A. Neal, P. Ruzicka, C. Cowden, J. Hoffman, M. T. Pérez García-Estañ, G. Bachy, Guillaume Unal, J. T. Linnemann, Andreas Hoecker, A. N. Sisakyan, A. Artamonov, A. V. Larionov, R. C. W. Henderson, M. J. Shochet, Alexandre Rozanov, Edmund Dawe, Claudio Santoni, Y. A. Tikhonov, David Yu, Evgeny Starchenko, M. Mechtel, C. 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Zhao, Monica D'Onofrio, I. Nasteva, Driss Benchekroun, Jos Vermeulen, D. Breton, Konstantinos Nikolopoulos, A. Bruni, Teng Jian Khoo, Kunihiro Nagano, L. Moneta, S. Eckweiler, B. Budick, I. Wilhelm, M. De Oliveira Branco, N. I. Bozhko, D. V. Dedovich, Elizaveta Shabalina, J. Ferland, Andrea Sansoni, J. Poll, G. Ordonez, S. Baker, L. M. Gilbert, G. T. Jones, M. Cirilli, Alison Lister, J. A. Gray, Rinat Fakhrutdinov, E. Spiriti, Stefania Spagnolo, R. Porter, Martine Bosman, H. Nomoto, E. Hazen, Sergio Gonzalez-Sevilla, M. Mikuž, Y. Zolnierowski, E. J. Buis, M. Aurousseau, M. Groh, Lucio Cerrito, Kerstin Lantzsch, Jochen Schieck, C. Belanger-Champagne, T. Del Prete, John Rutherfoord, Massimo Caccia, Holger Schulz, A. Phan, Filippo Ceradini, Krzysztof Korcyl, S. Campana, Martin Maß, S. T. French, C. A. Magrath, R. Schwierz, J. Knobloch, V. M. Romanov, Andrea Catinaccio, Rachel Maria Avramidou, Cigdem Issever, Song-Ming Wang, A. Leung Fook Cheong, Jana Schaarschmidt, I. A. Christidi, N. Ghodbane, D. Kuhn, D. Evangelakou, M. J. Oreglia, H. Wahlen, Stan Bentvelsen, T. Vu Anh, G. Volpini, Stefan Kaiser, Shigeru Odaka, H. von Radziewski, Daniel Muenstermann, I. Massa, A. J. Martin, C. Vellidis, Christophe Clement, J. Weber, Vipul Jain, Dominique Pallin, Rosy Nicolaidou, C. Pizio, Timothy Andeen, C. Grah, Z. Zhan, Jianming Qian, G. Tong, A. Borisov, Vincenzo Canale, W. Iwanski, A. G. Myagkov, L. Duflot, K. Jelen, E. Petit, Andrey Soukharev, A. Hidvegi, B. Nicquevert, A. Bertin, M. Tylmad, Calin Alexa, C. Wright, J. A. Bogaerts, T. N. Addy, Zhijun Liang, F. Bertinelli, Tomas Sykora, Jyothsna Rani Komaragiri, Mark Slater, Valery Schegelsky, F. Garberson, K. E. Johansson, Mark Stockton, Yoichi Ikegami, L. Chikovani, Pavol Strizenec, V. Sopko, V. A. Korotkov, Siegfried Wenig, T. J. Sloan, I. Torchiani, Jovan Mitrevski, Murrough Landon, Peter Jenni, Q. T. Shao, Hongfang Liu, S. Aoun, P. Giusti, J. Sloper, Paul Tipton, Margherita Primavera, A. Do Valle Wemans, M. Kelly, M. Strang, Olivier Arnaez, T. Akdogan, Elliot Lipeles, Saleh Sultansoy, C. Daum, R. Tanaka, T. Göpfert, I. Turk Cakir, Andreas Warburton, M. Ramstedt, M. C. Morone, Kazunori Hanagaki, G. Nanava, M. E. Zeller, E. Sedykh, G. Calderini, Carmen García, J. Lys, F. Föhlisch, Allen Mincer, M. V. Purohit, Uli Schäfer, Dirk L. Hoffmann, Junji Tojo, Ehud Duchovni, A. G. Kholodenko, S. J. Park, Paolo Camarri, Stefan Tapprogge, Mario Lassnig, A. Maio, C. Conta, Ralf P. Richter, Christopher J. Kenney, B. M. Waugh, F. Sarri, A. S. Kozhin, David Francis, Marcello Fanti, J. Colas, A. J. Lowe, A. Boveia, Ki Lie, T. Spreitzer, K. Miyazaki, J. Machado Miguens, Fumihiko Ukegawa, Andrea Formica, Venetios Polychronakos, V. Perez Reale, Yona Oren, R. A. McLaren, Eram Rizvi, L. La Rotonda, I. Hruska, M. Villaplana Perez, R. Herrberg, C. P. Buszello, Stephanie Majewski, Daniel Fournier, P. Yu Nechaeva, Xiaohu Sun, I. Stekl, P. Steinbach, G. M. Kolachev, Marzio Nessi, E. Jankowski, Martin Rybar, A. Seiden, T. Hayakawa, James Catmore, Robert Kehoe, W. E. Cleland, Renat Sadykov, Rudiger Voss, Georges Azuelos, Nick Barlow, Barry King, F. Alessandria, Helena Santos, Ricardo Neves, Fred R. Hirsch, Bertrand Laforge, K. H. Becks, G. Luijckx, David J. Smith, A. Filippas, O. Gutzwiller, M. Della Pietra, S. Gonzalez, Marco Schioppa, I. Jen-La Plante, G. Tzanakos, Andrea Bocci, M. Cooke, B. Sellden, K. K. Temming, Y. F. Ryabov, Nikola Makovec, Dave Charlton, Xiaoqin Li, Hulin Wang, A. Ahmad, Corinne Goy, C. Lapoire, Diane Cinca, Reiner Klingenberg, Helmut Wolters, Vladimir Nikolaenko, Z. Weng, A. Penson, Ian Michael Nugent, Muhammad Alhroob, P. Conde Muiño, Evelina Vassileva Bouhova-Thacker, Eugen Ertel, Georgios Tsipolitis, Sven Menke, A. Lupi, Mogens Dam, Victor Maleev, Karl Jakobs, Xie Yijin, Peter Schacht, Mauro Donegà, M. Jimenez Belenguer, M. Turala, O. Kvasnicka, H. Czirr, Frank Paige, Else Lytken, Charles Leggett, M. Rammes, Fabian Huegging, C. M. Hawkes, A. M. Zaitsev, F. Broggi, T. Mclaughlan, M. Mazzanti, E. De La Cruz-Burelo, J. R.A. Booth, D. Fasching, C. Ruwiedel, Thorsten Wengler, O. C. Jonsson, V. Savinov, Murdock Gilchriese, I. Satsounkevitch, F. Quinonez, Andrea Ventura, Michael Solar, A. Bangert, B. Åsman, M. Klemetti, Oldrich Kepka, F. Cataneo, A. Richards, Ulrich Parzefall, M. Ziolkowski, Alexander Bogdanchikov, Amanda R. Vest, Speranza Falciano, V. Kaushik, T. Meguro, Andreas Redelbach, Farid Ould-Saada, L. De Mora, B. Gosdzik, K. Facius, A. Di Ciaccio, C. Driouichi, Michael A. Strauss, M. Johansen, Voica Radescu, Driss Goujdami, C. Suhr, J. A. Parsons, Stefan Koperny, Julie Kirk, Susanne Kersten, Sebastian Grinstein, R. Ichimiya, Wolfgang Mader, Kendall Reeves, H. Landsman, C. Topfel, B. De Lotto, Emmerich Kneringer, D. van der Ster, Donatella Cavalli, U. Mallik, Mikhail Mineev, John Penwell, P. Hansson, Heiko Lacker, A. Kreisel, J. A. Ernst, F. Etienne, R. Mameghani, G. Lenzen, Dave Britton, Chiara Roda, Børge Kile Gjelsten, A. J. Fowler, James Boyd, D. Romero Maltrana, X. S. Anduaga, A. V. Ivashin, P. Miele, Dimitris Varouchas, Manolis Dris, G. Mahout, Shogo Okada, C. Guicheney, H. J. Yang, Juergen Kroseberg, A. T. Doyle, L. Labarga, B. Gaur, Dominick Olivito, Karel Smolek, Werner Wiedenmann, J. M. Foster, E. Castaneda-Miranda, A. G. Olchevski, Markus Schumacher, Frederic Brochu, Ryszard Stroynowski, T. Doherty, J. R. Lessard, Paul Nilsson, S. Prasad, D. Pomeroy, Alberto Annovi, M. Imhaeuser, Armin Michael Nairz, A. Reinsch, D. Whittington, A. A. Carter, Roger Jones, A. Firan, E. Bergeaas Kuutmann, Are Strandlie, Andrew Brandt, Fernando Marroquim, Frank Seifert, R. Engelmann, M. Wittgen, Ariel Schwartzman, S. Fratina, J. M. Maugain, A. Loginov, Marumi Kado, E. Urkovsky, James Frost, Pier-Olivier Deviveiros, Jonas Strandberg, M. Uhrmacher, A. Beddall, N. Giokaris, Giora Mikenberg, Wouter Verkerke, C. J.W.P. Timmermans, Lixin Ma, D. Typaldos, A. D'Orazio, H. von der Schmitt, E. Valladolid Gallego, X. Espinal Curull, Diego Casadei, Doris Chromek-Burckhart, Tadaaki Isobe, J. N. Lilley, M. Cascella, W. Ji, Tatsumi Koi, Maurice Garcia-Sciveres, V. V. Zmouchko, P. Perus, T. Kobayashi, Petr Andreevich Gorbounov, Torre Wenaus, D. Milstein, Dominic Hirschbuehl, S. Sandvoss, P. Federic, G. A. Chelkov, Alex Martyniuk, Wolfgang Wagner, A. Chilingarov, Marie-Hélène Genest, S. Subramania, O. Vitells, Carsten Hensel, M. Dameri, Luca Fiorini, G. Y. Mitrofanov, Alberto Belloni, M. Leahu, Aldo Saavedra, Atsuhiko Ochi, F. Polci, M. Maaßen, S. Di Luise, James Howarth, Stephen Haywood, Sotirios Vlachos, Walter Lampl, V. Moeller, S. Zenz, J. Inigo-Golfin, David Malon, Stefan Guindon, D. Lumb, B. M. Hawes, E. Dobson, E. Sarkisyan-Grinbaum, Ewa Stanecka, Enrico Tassi, F. Marzano, G. Nunes Hanninger, Jean François Marchand, Jens Dopke, Gokhan Unel, F. Dudziak, Richard Brenner, Marisa Sandhoff, A. Mitra, B. Radics, S. Y. Nesterov, Arely Cortes-Gonzalez, Alexander Milov, A. Irles Quiles, Matthias Klein, Alexey Talyshev, R. Giordano, Vladimir Cindro, Pierre-Hugues Beauchemin, M. Weber, A. Reichold, Konrad Kleinknecht, R. Maenner, Teresa Barillari, V. M. Kotov, Seema Bahinipati, Y. Ilchenko, G. Romeo, Marine Kuna, M. Kenyon, Sara Diglio, Steven Goldfarb, Z. G. Zhao, G. Ciapetti, Peter Loch, W. Mohr, J. B. De Vivie De Regie, Jan Kretzschmar, D. R. Quarrie, E. E. Schmidt, F. Parodi, D. Fellmann, C. C. Young, Anna Kaczmarska, N. Grau, Marina Cobal, A. Tonazzo, David Miller, Jiri Masik, Lawrence Lee, Oleg Fedin, S. Vahsen, W. T. Meyer, Dorothee Schaile, Michael Boehler, Bartosz Mindur, Lianyou Shan, Richard Nisius, Melissa Ridel, C. W. Loh, Jianyong Lu, Srinivasan Rajagopalan, Irene Vichou, Hal Evans, B. A. Dolgoshein, Y. Mahalalel, J. Snow, Ilija Vukotic, Jan Godlewski, M. Rijpstra, Jalal Abdallah, E. Strauss, G. Vegni, C. Schmitt, Erez Etzion, M. Werner, Francois Corriveau, Scott Snyder, Carlos Lacasta, Masaya Ishino, E. Turlay, Elias Coniavitis, K. Mueller, Victor Kukhtin, D. Ludwig, P. Ryan, G. Vandoni, J. Boudreau, P. S. Wells, M. A. Dufour, A. M. Castaneda Hernandez, Chong-Yu Xu, C. Melachrinos, J. Hrivnac, H. Guler, Vladimir Vinogradov, M. A. Wildt, B. Toczek, Gabriel Stoicea, N. Kundu, John Baines, Sergei Chekanov, J. Godfrey, A. Blondel, Pavel Staroba, E. Perez Codina, Giuseppe Costa, Max Baak, K. J. Grahn, Claudio Gatti, Stefan Kluth, J. Fleckner, A. Khomich, M. A. Pleier, Eleni Mountricha, Didier Lacour, Ioannis Nomidis, P. S. Mangeard, Oleg Bulekov, S. Viel, C. Deluca, D. Dzahini, Yueh-Feng Liu, S. Schuh, M. Kaneda, S. Rzaeva, Christoph Amelung, F. G. Oakham, S. Fleischmann, Oxana Smirnova, T. Todorov, T. J. McMahon, Danilo Giugni, V. Rojo, D. S. Damiani, Otmar Biebel, Konstantinos Bachas, F. Varela Rodriguez, Francesco Lanni, O. Gaumer, Aaron James Armbruster, V. Ryadovikov, S. Koenig, R. P. Thun, Giuseppe Iacobucci, Thomas Koffas, Frank Ellinghaus, Arnaud Foussat, R. Mehdiyev, T. Rador, Isabel Marian Trigger, Louise Skinnari, R. J. Homer, Antonio Baroncelli, Ulrich Landgraf, J. Schultes, Mauro Villa, N. Panikashvili, Claire Gwenlan, Vincent Garonne, M. Hohlfeld, X. Portell Bueso, Sandro Palestini, J. Snuverink, R. R. Rios, S. Rodier, I. Dolenc, J. Lellouch, D. Y. Bardin, L. Miralles Verge, E. Auge, R. W. Clifft, G. Brown, Andre Kruth, Julien Donini, Pascal Pralavorio, Ilias Efthymiopoulos, Sandra Kortner, S. Fazio, V. Vorwerk, Vadim Kostyukhin, Lamberto Luminari, M. Shamim, Y. Pylypchenko, Catrin Bernius, Remi Lafaye, Theodota Lagouri, G. Cortiana, Paolo Iengo, M. Marx, S. I. Buda, Hartmut Sadrozinski, K. W. McFarlane, N. Massol, Douglas M. Hawkins, D. S. Popovic, E. L. Barberio, Marco Delmastro, M. Fiascaris, Marina Rotaru, N. Dressnandt, Frédéric Chevallier, H. van der Graaf, S. N. White, Ilya Korolkov, Fridolin Dittus, Y. Munwes, Moritz Backes, Sofia Chouridou, Jason Nielsen, Armen Vartapetian, Maria-Teresa Dova, P. Giovannini, E. Ptacek, Tom McCarthy, M. C. Conidi, Zhiqing Zhang, A. Paoloni, R. Febbraro, M. Warsinsky, M. S. Levitski, E. Laisne, Bernard Aubert, Benjamin Trocmé, M. Moreno Llácer, Bing Li, Shlomit Tarem, Gabriela Navarro, J. Klaiber-Lodewigs, Tiesheng Dai, J. J. Veillet, J. Morel, Guennadi Borissov, Francesco Lacava, M. Tsiakiris, Michael Begel, L. De Nooij, S. Hillert, S. Persembe, M. Saleem, Gustaaf Brooijmans, Dirk-Uwe Bartsch, M. E. Sevior, Gabriella Gaudio, E. Solfaroli Camillocci, C. Del Papa, B. Szeless, K. Perez, P. Stavina, Gerjan Bobbink, Marisilvia Donadelli, Judita Mamuzic, Uta Klein, Maria Smizanska, D. Goldin, D. Imbault, N. Krieger, P. Matricon, M. Abolins, V. N. Goryachev, A. Tonoyan, M. Virchaux, J. A. Wilson, P. V.M. Da Silva, Takahiko Kondo, William Buttinger, S. P. Whitaker, B. M. Salvachua Ferrando, A. Canepa, J. Molina-Perez, I. van Vulpen, Andrzej Zemla, Giulio Aielli, Fernando Barreiro, Itamar Roth, Iacopo Vivarelli, M. Dosil, Xin Wu, Z. Zajacova, Eduardo Ros, Till Eifert, M. I. 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Bauer, Flera Rizatdinova, T. Sugimoto, John Derek Chapman, W. Kozanecki, S. O. Holmgren, P. G. Bright-Thomas, Martin Goebel, Katsuo Tokushuku, J. Sondericker, E. Brodet, S. Patricelli, T. O. Niinikoski, R. Zitoun, Marcella Capua, E. Rauter, Y. Suzuki, E. Segura, Marc Dobson, Andreas Battaglia, S. Johnert, J. L. Lane, Stephen Burke, S. Sushkov, Giorgi Arabidze, Philip Phillips, Samuel Silverstein, E. Graziani, Ilya Tsukerman, Guenter Duckeck, Michael Flowerdew, Reyhaneh Rezvani, M. Gruwe, H. H. Williams, Antonio Policicchio, D. Sherman, E. van der Kraaij, Sharka Todorova-Nova, T. Sasaki, S. Youssef, Christoph Posch, A. D. Hershenhorn, J. P. Dauvergne, M. Aleppo, C. Biscarat, K. K. Gan, Brian Petersen, Juan Antonio Aguilar-Saavedra, Tamar Djobava, W. H. Bell, L. Di Ciaccio, A. Zsenei, Benjamin Wynne, A. De Salvo, Steinar Stapnes, R. Ueno, L. P. Says, Koji Terashi, Jongmin Lee, A. Antonaki, M. Raas, Craig Buttar, A. P. Vorobiev, R. Bernhard, B. Lundberg, M. Olcese, S. Montesano, D. Greenfield, Michele Livan, Annick Lleres, J. Grognuz, Abbas Kenan Ciftci, Karlheinz Meier, Rui Wang, Josh Moss, Enrique Kajomovitz, C. Handel, J. Almond, J. Nadal, G. Rudolph, M. Schram, Louis Helary, C. Horn, Timothy Barklow, Daria Zieminska, E. Magradze, P. Valente, Andrei Snesarev, J. A. Macana Goia, R. D. Schamberger, C. Lasseur, Ahmimed Ouraou, V. V. Ammosov, Alan Litke, Mieczyslaw Witold Krasny, Yann Coadou, L. K. Gladilin, B. Pinto, Anna Mastroberardino, C. Gong, Bruno Lenzi, T. P. Kokott, Carla Sbarra, Gilbert Poulard, Yuta Takahashi, V. Zutshi, Amanda Cooper-Sarkar, W.J. Willis, S. Schaetzel, Marcin Wladyslaw Wolter, Peter Wienemann, Marek Idzik, D. Rousseau, Nicole Ruckstuhl, O. M. Harris, G. F. Moorhead, Antonio Ereditato, Alexander Grillo, J. E. Sundermann, M. Miñano, Harinder Singh Bawa, Oliver Kortner, C. Zendler, M. Aliyev, Brigitte Vachon, V. Grassi, Peter Sturm, Heather Gray, D. Fortin, O. Pirotte, R. Yoosoofmiya, R. E. Blair, A. Cazzato, A. Kapliy, Riccardo Vari, Jong-Sung Yu, Maria Pilar Casado, G. L. Darlea, W. G. Plano, V. I. Koreshev, J. Walbersloh, K. Benslama, S. Rajek, Robert McPherson, G. L. Glonti, Attila Krasznahorkay, Nicola Semprini-Cesari, H. O. Danielsson, Andrew D. Hamilton, J. Blocki, N. Guttman, T. Cuhadar Donszelmann, R. S. Orr, I. P. Duerdoth, M. V. Gallas, N. J. Cooper-Smith, T. Nishiyama, Igor Gavrilenko, Massimo Lamanna, Y. Gusakov, H. S. Chen, Antonio Limosani, V. O. Tikhomirov, T. Nunnemann, K. Edmonds, R. Di Nardo, Vaclav Vacek, V. Andrei, Dirk Zerwas, Raymond Brock, G. Sauvage, Giovanni Crosetti, Giovanna Bruni, D. R. Hadley, Klaus Mönig, Federica Legger, Valery Khovanskiy, Mihail Chizhov, V. Lombardo, Bruno Mansoulie, Paul Newman, Stanislav Pospisil, Ph. Schune, W-M. Yao, H. Khandanyan, Clara Troncon, Alexei Klimentov, Masaharu Nomachi, Y. Tanaka, B. Stugu, Nigel Hessey, M. Limper, Olga Beltramello, Nicoletta Garelli, J. Yamaoka, Michael R. Wessels, M. Imori, You Zhou, Aranzazu Ruiz-Martinez, Alison Holmes, J. Novakova, P. Zarzhitsky, L. Gauthier, Ricardo Gonçalo, Paul Jackson, G. E. Pospelov, Mihai Ciubancan, V. B. Bobrovnikov, D. A. Forbush, F. Cerutti, Kathryn Grimm, B. Nordkvist, B. D. Cooper, M. Morii, V. Castillo Gimenez, L. Chen, S. H. Kim, A. Renaud, M. Mudrinic, Sergey Kuleshov, M. Nožička, P. Puzo, Yang Gao, Elliott Cheu, T. Henß, G. Jin, A. Bogouch, P. Amaral, Andrea Favareto, M. Gouanère, P. Cwetanski, John Huth, N. Vlasov, M. I. Besana, H. Kiyamura, J. W. Chapman, G. Marchiori, Alexander Khanov, K. Harrison, H. Boterenbrood, H. Kagan, C. D. Cojocaru, A. Siebel, Michael Rijssenbeek, A.S. Vovenko, T. Stockmanns, Gary Boorman, Juan Terron, E. Gornicki, V. J. Guarino, Domizia Orestano, C. Fabre, V. G. Zaets, L. Bugge, Simone Monzani, Avi Gershon, A. Salamon, V. Zhuravlov, J. Coggeshall, Michael Dührssen, K. Tani, F. Georgatos, Richard Bates, C. R. Boddy, V. Juranek, Troels Petersen, S. Dean, K. Kessoku, I. Mussche, N. P. Gollub, S. González de la Hoz, C. Lebel, H. G. Sander, Hans Peter Beck, R. Zimmermann, M. Martinez, J. A. Valls Ferrer, M. L. Kocian, A. V. Pleskach, A. S. Thompson, B. Butler, Thomas Naumann, P. R. Norton, Markus Nordberg, E. Wulf, Dusan Bruncko, Mark Hatch, A. M. Bach, Vakhtang Tsiskaridze, Maria Curatolo, Saminder Dhaliwal, F. Tarrade, G. Akimoto, Riccardo-Maria Bianchi, Paolo Bagnaia, S. Kabana, J. N. Butler, Anyes Taffard, Nuno Anjos, M. Simonyan, A. J. Lankford, D. Prieur, Th. Müller, Joseph Izen, S. Antonelli, John Morris, Antoine Marzin, Juergen Thomas, Nicolas Ellis, Ruslan Mashinistov, Alessandra Ciocio, K. Sliwa, Shinichi Shimizu, L. Han, G. G.G. Massaro, Gen Kawamura, J. Treis, Wim Lavrijsen, Enrico Pasqualucci, V. F. Chepurnov, P. L. Rosendahl, Roberto Ferrari, R. Ishmukhametov, Anna Sfyrla, D. Tardif, Marcella Bona, V. V. Kabachenko, Abdenour Lounis, Ayda Beddall, Nathalie Besson, M. Robinson, Daniel Dobos, A. Cavallari, T. Greenshaw, Andrej Gorišek, Sophie Trincaz-Duvoid, Kazuhiko Hara, T. Frank, C. Dennis, Craig Blocker, A. Barbaro Galtieri, A. Mapelli, Gregor Herten, S. Cabrera Urbán, C. Geweniger, P. K. Mal, D. M. Gingrich, J. Glatzer, Enrico Rossi, H. S. Bansil, R. Calkins, Daniela Salvatore, A. Mayne, I. Orlov, Frank Filthaut, C. Caramarcu, J. Degenhardt, Anne-Isabelle Etienvre, F. Diblen, J. Ferencei, Michael Shupe, L. Lipinsky, G. Alexandre, S. Ventura, Pavel Reznicek, Chiara Meroni, Bruce Yabsley, Deywis Moreno, N. R. Nation, J. Griffiths, M. P. Goulette, Elzbieta Banas, A. Larner, T. Kanno, E. Le Menedeu, Stefan Simion, Serban Constantinescu, Takashi Matsushita, Adele Rimoldi, A. P. Colijn, X. Prudent, S. Kotov, G. A. Cowan, Paul Dervan, L. Köpke, L. V. Kalinovskaya, Darren Price, Fedor Prokoshin, Peter Kluit, R. Caputo, J. E. Pilcher, B. Koblitz, Pierre Savard, Matteo Cavalli-Sforza, T. Hott, Duc Ta, D. Oliveira Damazio, E. E. Kluge, W. Blum, J. Groth-Jensen, V. 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Rescigno, S. Resconi, B. Resende, P. Reznicek, R. Rezvani, A. Richards, R. Richter, E. Richter-Was, M. Ridel, S. Rieke, M. Rijpstra, M. Rijssenbeek, A. Rimoldi, L. Rinaldi, R. R. Rios, I. Riu, G. Rivoltella, F. Rizatdinova, E. Rizvi, S. H. Robertson, A. Robichaud-Veronneau, D. Robinson, J. E. M. Robinson, M. Robinson, A. Robson, J. G. Rocha de Lima, C. Roda, D. Roda Dos Santos, S. Rodier, D. Rodriguez, Y. Rodriguez Garcia, A. Roe, S. Roe, O. Røhne, V. Rojo, S. Rolli, A. Romaniouk, V. M. Romanov, G. Romeo, D. Romero Maltrana, L. Roos, E. Ros, S. Rosati, M. Rose, G. A. Rosenbaum, E. I. Rosenberg, P. L. Rosendahl, L. Rosselet, V. Rossetti, E. Rossi, L. P. Rossi, L. Rossi, M. Rotaru, I. Roth, J. Rothberg, I. Rottländer, D. Rousseau, C. R. Royon, A. Rozanov, Y. Rozen, X. Ruan, I. Rubinskiy, B. Ruckert, N. Ruckstuhl, V. I. Rud, G. Rudolph, F. Rühr, A. Ruiz-Martinez, E. Rulikowska-Zarebska, V. Rumiantsev, L. Rumyantsev, K. Runge, O. Runolfsson, Z. Rurikova, N. A. Rusakovich, D. R. Rust, J. 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Takeda, T. Takeshita, M. Talby, A. Talyshev, M. C. Tamsett, J. Tanaka, R. Tanaka, S. Tanaka, S. Tanaka, Y. Tanaka, K. Tani, N. Tannoury, G. P. Tappern, S. Tapprogge, D. Tardif, S. Tarem, F. Tarrade, G. F. Tartarelli, P. Tas, M. Tasevsky, E. Tassi, M. Tatarkhanov, C. Taylor, F. E. Taylor, G. Taylor, G. N. Taylor, W. Taylor, M. Teixeira Dias Castanheira, P. Teixeira-Dias, K. K. Temming, H. Ten Kate, P. K. Teng, Y. D. Tennenbaum-Katan, S. Terada, K. Terashi, J. Terron, M. Terwort, M. Testa, R. J. Teuscher, C. M. Tevlin, J. Thadome, J. Therhaag, T. Theveneaux-Pelzer, M. Thioye, S. Thoma, J. P. Thomas, E. N. Thompson, P. D. Thompson, P. D. Thompson, A. S. Thompson, E. Thomson, M. Thomson, R. P. Thun, T. Tic, V. O. Tikhomirov, Y. A. Tikhonov, C.J.W.P. Timmermans, P. Tipton, F. J. Tique Aires Viegas, S. Tisserant, J. Tobias, B. Toczek, T. Todorov, S. Todorova-Nova, B. Toggerson, J. Tojo, S. Tokár, K. Tokunaga, K. Tokushuku, K. Tollefson, M. Tomoto, L. Tompkins, K. Toms, A. Tonazzo, G. Tong, A. Tonoyan, C. Topfel, N. D. Topilin, I. Torchiani, E. Torrence, E. Torró Pastor, J. Toth, F. Touchard, D. R. Tovey, D. Traynor, T. Trefzger, J. Treis, L. Tremblet, A. Tricoli, I. M. Trigger, S. Trincaz-Duvoid, T. N. Trinh, M. F. Tripiana, N. Triplett, W. Trischuk, A. Trivedi, B. Trocmé, C. Troncon, M. Trottier-McDonald, A. Trzupek, C. Tsarouchas, J.C-L. Tseng, M. Tsiakiris, P. V. Tsiareshka, D. Tsionou, G. Tsipolitis, V. Tsiskaridze, E. G. Tskhadadze, I. I. Tsukerman, V. Tsulaia, J.-W. Tsung, S. Tsuno, D. Tsybychev, A. Tua, J. M. Tuggle, M. Turala, D. Turecek, I. Turk Cakir, E. Turlay, P. M. Tuts, A. Tykhonov, M. Tylmad, M. Tyndel, D. Typaldos, H. Tyrvainen, G. Tzanakos, K. Uchida, I. Ueda, R. Ueno, M. Ugland, M. Uhlenbrock, M. Uhrmacher, F. Ukegawa, G. Unal, D. G. Underwood, A. Undrus, G. Unel, Y. Unno, D. Urbaniec, E. Urkovsky, P. Urquijo, P. Urrejola, G. Usai, M. Uslenghi, L. Vacavant, V. Vacek, B. Vachon, S. Vahsen, C. Valderanis, J. Valenta, P. Valente, S. Valentinetti, S. Valkar, E. Valladolid Gallego, S. Vallecorsa, J. A. Valls Ferrer, H. van der Graaf, E. van der Kraaij, E. van der Poel, D. van der Ster, B. Van Eijk, N. van Eldik, P. van Gemmeren, Z. van Kesteren, I. van Vulpen, W. Vandelli, G. Vandoni, A. Vaniachine, P. Vankov, F. Vannucci, F. Varela Rodriguez, R. Vari, E. W. Varnes, D. Varouchas, A. Vartapetian, K. E. Varvell, V. I. Vassilakopoulos, F. Vazeille, G. Vegni, J. J. Veillet, C. Vellidis, F. Veloso, R. Veness, S. Veneziano, A. Ventura, D. Ventura, S. Ventura, M. Venturi, N. Venturi, V. Vercesi, M. Verducci, W. Verkerke, J. C. Vermeulen, A. Vest, M. C. Vetterli, I. Vichou, T. Vickey, G. H. A. Viehhauser, S. Viel, M. Villa, M. Villaplana Perez, E. Vilucchi, M. G. Vincter, E. Vinek, V. B. Vinogradov, M. Virchaux, S. Viret, J. Virzi, A. Vitale, O. Vitells, I. Vivarelli, F. Vives Vaque, S. Vlachos, M. Vlasak, N. Vlasov, A. Vogel, P. Vokac, M. Volpi, G. Volpini, H. von der Schmitt, J. von Loeben, H. von Radziewski, E. von Toerne, V. Vorobel, A. P. Vorobiev, V. Vorwerk, M. Vos, R. Voss, T. T. Voss, J. H. Vossebeld, A. S. Vovenko, N. Vranjes, M. Vranjes Milosavljevic, V. Vrba, M. Vreeswijk, T. Vu Anh, R. Vuillermet, I. Vukotic, W. Wagner, P. Wagner, H. Wahlen, J. Wakabayashi, J. Walbersloh, S. Walch, J. Walder, R. Walker, W. Walkowiak, R. Wall, P. Waller, C. Wang, H. Wang, J. Wang, J. C. Wang, R. Wang, S. M. Wang, A. Warburton, C. P. Ward, M. Warsinsky, P. M. Watkins, A. T. Watson, M. F. Watson, G. Watts, S. Watts, A. T. Waugh, B. M. Waugh, J. Weber, M. Weber, M. S. Weber, P. Weber, A. R. Weidberg, J. Weingarten, C. Weiser, H. Wellenstein, P. S. Wells, M. Wen, T. Wenaus, S. Wendler, Z. Weng, T. Wengler, S. Wenig, N. Wermes, M. Werner, P. Werner, M. Werth, M. Wessels, K. Whalen, S. J. Wheeler-Ellis, S. P. Whitaker, A. White, M. J. White, S. White, S. R. Whitehead, D. Whiteson, D. Whittington, F. Wicek, D. Wicke, F. J. Wickens, W. Wiedenmann, M. Wielers, P. Wienemann, C. Wiglesworth, L. A. M. Wiik, A. Wildauer, M. A. Wildt, I. Wilhelm, H. G. Wilkens, J. Z. Will, E. Williams, H. H. Williams, W. Willis, S. Willocq, J. A. Wilson, M. G. Wilson, A. Wilson, I. Wingerter-Seez, S. Winkelmann, F. Winklmeier, M. Wittgen, M. W. Wolter, H. Wolters, G. Wooden, B. K. Wosiek, J. Wotschack, M. J. Woudstra, K. Wraight, C. Wright, B. Wrona, S. L. Wu, X. Wu, Y. Wu, E. Wulf, R. Wunstorf, B. M. Wynne, L. Xaplanteris, S. Xella, S. Xie, Y. Xie, C. Xu, D. Xu, G. Xu, B. Yabsley, M. Yamada, A. Yamamoto, K. Yamamoto, S. Yamamoto, T. Yamamura, J. Yamaoka, T. Yamazaki, Y. Yamazaki, Z. Yan, H. Yang, U. K. Yang, Y. Yang, Y. Yang, Z. Yang, S. Yanush, W-M. Yao, Y. Yao, Y. Yasu, J. Ye, S. Ye, M. Yilmaz, R. Yoosoofmiya, K. Yorita, R. Yoshida, C. Young, S. Youssef, D. Yu, J. Yu, J. Yu, L. Yuan, A. Yurkewicz, V. G. Zaets, R. Zaidan, A. M. Zaitsev, Z. Zajacova, Yo.K. Zalite, L. Zanello, P. Zarzhitsky, A. Zaytsev, M. Zdrazil, C. Zeitnitz, M. Zeller, P. F. Zema, A. Zemla, C. Zendler, A. V. Zenin, O. Zenin, T. Ženiš, Z. Zenonos, S. Zenz, D. Zerwas, G. Zevi della Porta, Z. Zhan, D. Zhang, H. Zhang, J. Zhang, X. Zhang, Z. Zhang, L. Zhao, T. Zhao, Z. Zhao, A. Zhemchugov, S. Zheng, J. Zhong, B. Zhou, N. Zhou, Y. Zhou, C. G. Zhu, H. Zhu, Y. Zhu, X. Zhuang, V. Zhuravlov, D. Zieminska, B. Zilka, R. Zimmermann, S. Zimmermann, S. Zimmermann, M. Ziolkowski, R. Zitoun, L. Živković, V. V. Zmouchko, G. Zobernig, A. Zoccoli, Y. Zolnierowski, A. Zsenei, M. zur Nedden, V. Zutshi, L. Zwalinski, Doğuş Üniversitesi, Fen Edebiyat Fakültesi, Fizik Bölümü, TR3959, Çetin, Serkant Ali, G., Aad, Bianco, Michele, G., Chiodini, M. R., Coluccia, Gorini, Edoardo, Primavera, Margherita, Spagnolo, Stefania Antonia, Ventura, Andrea, Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Joseph Fourier - Grenoble 1 (UJF)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), UAM. Departamento de Física Teórica, Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC), Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Pierre et Marie Curie - Paris 6 (UPMC)-AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut Polytechnique de Grenoble - Grenoble Institute of Technology-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Université de Strasbourg (UNISTRA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Universidade do Minho, Abdelalim Aly, Ahmed Aly, Alexandre, Gauthier, Backes, Moritz, Bell, Paul, Bell, William, Berglund, Frida Elina, Blondel, Alain, Bucci, Francesca, Clark, Allan Geoffrey, Dao, Valerio, Efthymiopoulos, Ilias, Ferrere, Didier, Gadomski, Szymon, Garcia Navarro, Jose Enrique, Gaumer, Olivier, Gonzalez Sevilla, Sergio, Goulette, Marc, Hamilton, Andrew, Leger, Annie, Lister, Alison, Macina-Buono, Daniela, Martin Dit Latour, Bertrand, Mikulec, Bettina, Moneta, Lorenzo, Mora Herrera, Maria Clemencia Rosario, Morone, Maria Cristina, Nektarijevic, Snezana, Orellana, Frédérik, Pasztor, Arpad, Pohl, Martin, Robichaud-Veronneau, Andrée, Rosselet, Laurent, Urquijo, Phillip, Wu, Xin, and ATLAS Collaboration (ukupan broj autora: 3048)

Subjects
Particle physics, MISSING TRANSVERSE ENERGY, Ciências Naturais::Ciências Físicas, Atlas detector, Ciências Físicas [Ciências Naturais], FIS/04 - Fisica Nucleare e Subnucleare, General Physics and Astronomy, FOS: Physical sciences, transverse energy: missing-energy, ATLAS, universal extra dimension, compactification, CERN LHC Coll, background, p p: interaction, final state: two-photon, photon: Kaluza-Klein, electroweak interaction: standard model: validity test, experimental results, 7000 GeV-cms, ddc:500.2, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, Nuclear physics, Universal extra dimension, High Energy Physics - Experiment (hep-ex), 0103 physical sciences, ddc:550, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], diphoton, events, transverse energy, proton-proton collisions, Hadron, ddc:530, High Energy Physics, Specific model, 010306 general physics, Nuclear Experiment, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), QC, Physics, Large Hadron Collider, Science & Technology, Compactification (physics), 010308 nuclear & particles physics, Atlas (topology), Settore FIS/01 - Fisica Sperimentale, Física, FIS/01 - Fisica Sperimentale, Transverse plane, Col·lisions (Física nuclear), Experimental High Energy Physics, Universal Extra Dimensions, Física nuclear, High Energy Physics::Experiment, LHC, Particle Physics - Experiment
Abstract

A search for diphoton events with large missing transverse energy is presented. The data were collected with the ATLAS detector in proton-proton collisions at √s=7 TeV at the CERN Large Hadron Collider and correspond to an integrated luminosity of 3.1 pb−1. No excess of such events is observed above the standard model background prediction. In the context of a specific model with one universal extra dimension with compactification radius R and gravity-induced decays, values of 1/R, We wish to thank CERN for the efficient commissioning and operation of the LHC during this initial high-energy data-taking period as well as the support staff from our institutions without whom ATLAS could not be operated efficiently. We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF, DNSRC and Lundbeck Foundation, Denmark; ARTEMIS, European Union; IN2P3-CNRS, CEA-DSM/IRFU, France; GNAS, Georgia; BMBF, DFG, HGF, MPG and AvH Foundation, Germany; GSRT, Greece; ISF, MINERVA, GIF, DIP and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW, Poland; GRICES and FCT, Portugal; MERYS (MECTS), Romania; MES of Russia and ROSATOM, Russian Federation; JINR; MSTD, Serbia; MSSR, Slovakia; ARRS and MVZT, Slovenia; DST/NRF, South Africa; MICINN, Spain; SRC and Wallenberg Foundation, Sweden; SER, SNSF and Cantons of Bern and Geneva, Switzerland; NSC, Taiwan; TAEK, Turkey; STFC, the Royal Society and Leverhulme Trust, United Kingdom; DOE and NSF, United States of America. The crucial computing support from all WLCG partners is acknowledged gratefully, in particular, from CERN and the ATLAS Tier-1 facilities at TRIUMF (Canada), NDGF (Denmark, Norway, Sweden), CC-IN2P3 (France), KIT/GridKA (Germany), INFN-CNAF (Italy), NL-T1 (Netherlands), PIC (Spain), ASGC (Taiwan), RAL (UK) and BNL (USA) and in the Tier-2 facilities worldwide., info:eu-repo/semantics/publishedVersion

Published
2011
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31. Measurement of the inclusive isolated prompt photon cross section in pp collisions at √s=7 TeV with the ATLAS detector

Author

Aad, G., Abbott, B., Abdallah, J., Abdelalim, A. A., Abdesselam, A., Abdinov, O., Abi, B., Abolins, M., Abramowicz, H., Abreu, H., Acerbi, E., Acharya, B. S., Ackers, M., Adams, D. L., Addy, T. N., Adelman, J., Aderholz, M., Adomeit, S., Adragna, P., Adye, T., Aefsky, S., Aguilar-Saavedra, J. A., Aharrouche, M., Ahlen, S. P., Ahles, F., Ahmad, A., Ahsan, M., Aielli, G., Akdogan, T., Åkesson, T. P. A., Akimoto, G., Akimov, A. V., Alam, M. S., Alam, M. A., Albrand, S., Aleksa, M., Aleksandrov, I. N., Aleppo, M., Alessandria, F., Alexa, C., Alexander, G., Alexandre, G., Alexopoulos, T., Alhroob, M., Aliev, M., Alimonti, G., Alison, J., Aliyev, M., Allport, P. P., Allwood-Spiers, S. E., Almond, J., Aloisio, A., Alon, R., Alonso, A., Alonso, J., Alviggi, M. G., Amako, K., Amaral, P., Amelung, C., Ammosov, V. V., Amorim, A., Amorós, G., Amram, N., Anastopoulos, C., Andari, N., Andeen, T., Anders, C. F., Anderson, K. J., Andreazza, A., Andrei, V., Andrieux, M. -L., Anduaga, X. S., Angerami, A., Anghinolfi, F., Anjos, N., Annovi, A., Antonaki, A., Antonelli, M., Antonelli, S., Antos, J., Anulli, F., Aoun, S., Aperio Bella, L., Apolle, R., Arabidze, G., Aracena, I., Arai, Y., Arce, A. T. H., Archambault, J. P., Arfaoui, S., Arguin, J. -F., Arik, E., Arik, M., Armbruster, A. J., Arms, K. E., Armstrong, S. R., Arnaez, O., Arnault, C., Artamonov, A., Artoni, G., Arutinov, D., Asai, S., Asfandiyarov, R., Ask, S., Åsman, B., Asquith, L., Assamagan, K., Astbury, A., Astvatsatourov, A., Atoian, G., Aubert, B., Auerbach, B., Auge, E., Augsten, K., Aurousseau, M., Austin, N., Avramidou, R., Axen, D., Ay, C., Azuelos, G., Azuma, Y., Baak, M. A., Baccaglioni, G., Bacci, C., Bach, A. M., Bachacou, H., Bachas, K., Bachy, G., Backes, M., Badescu, E., Bagnaia, P., Bahinipati, S., Bai, Y., Bailey, D. C., Bain, T., Baines, J. T., Baker, O. K., Baker, S., Baltasar Dos Santos Pedrosa, F., Banas, E., Banerjee, P., Banerjee, Sw., Banfi, D., Bangert, A., Bansal, V., Bansil, H. S., Barak, L., Baranov, S. P., Barashkou, A., Barbaro Galtieri, A., Barber, T., Barberio, E. L., Barberis, D., Barbero, M., Bardin, D. Y., Barillari, T., Barisonzi, M., Barklow, T., Barlow, N., Barnett, B. M., Barnett, R. M., Baroncelli, A., Barr, A. J., Barreiro, F., Barreiro Guimarães Da Costa, J., Barrillon, P., Bartoldus, R., Barton, A. E., Bartsch, D., Bates, R. L., Batkova, L., Batley, J. R., Battaglia, A., Battistin, M., Battistoni, G., Bauer, F., Bawa, H. S., Beare, B., Beau, T., Beauchemin, P. H., Beccherle, R., Bechtle, P., Beck, H. P., Beckingham, M., Becks, K. H., Beddall, A. J., Beddall, A., Bednyakov, V. A., Bee, C., Begel, M., Behar Harpaz, S., Behera, P. K., Beimforde, M., Belanger-Champagne, C., Belhorma, B., Bell, P. J., Bell, W. H., Bella, G., Bellagamba, L., Bellina, F., Bellomo, G., Bellomo, M., Belloni, A., Belotskiy, K., Beltramello, O., Ben Ami, S., Benary, O., Benchekroun, D., Benchouk, C., Bendel, M., Benedict, B. H., Benekos, N., Benhammou, Y., Benjamin, D. 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Stahlman, R. Stamen, E. Stanecka, R. W. Stanek, C. Stanescu, S. Stapnes, E. A. Starchenko, J. Stark, P. Staroba, P. Starovoitov, A. Staude, P. Stavina, G. Stavropoulos, G. Steele, E. Stefanidis, P. Steinbach, P. Steinberg, I. Stekl, B. Stelzer, H. J. Stelzer, O. Stelzer-Chilton, H. Stenzel, K. Stevenson, G. A. Stewart, T. Stockmanns, M. C. Stockton, M. Stodulski, K. Stoerig, G. Stoicea, S. Stonjek, P. Strachota, A. R. Stradling, A. Straessner, J. Strandberg, S. Strandberg, A. Strandlie, M. Strang, E. Strauss, M. Strauss, P. Strizenec, R. Ströhmer, D. M. Strom, J. A. Strong, R. Stroynowski, J. Strube, B. Stugu, I. Stumer, J. Stupak, P. Sturm, D. A. Soh, D. Su, S. Subramania, Y. Sugaya, T. Sugimoto, C. Suhr, K. Suita, M. Suk, V. V. Sulin, S. Sultansoy, T. Sumida, X. Sun, J. E. Sundermann, K. Suruliz, S. Sushkov, G. Susinno, M. R. Sutton, Y. Suzuki, Yu. M. Sviridov, S. Swedish, I. Sykora, T. Sykora, B. Szeless, J. Sánchez, D. Ta, K. Tackmann, A. Taffard, R. Tafirout, A. Taga, N. Taiblum, Y. Takahashi, H. Takai, R. Takashima, H. Takeda, T. Takeshita, M. Talby, A. Talyshev, M. C. Tamsett, J. Tanaka, R. Tanaka, S. Tanaka, S. Tanaka, Y. Tanaka, K. Tani, N. Tannoury, G. P. Tappern, S. Tapprogge, D. Tardif, S. Tarem, F. Tarrade, G. F. Tartarelli, P. Tas, M. Tasevsky, E. Tassi, M. Tatarkhanov, C. Taylor, F. E. Taylor, G. Taylor, G. N. Taylor, W. Taylor, M. Teixeira Dias Castanheira, P. Teixeira-Dias, K. K. Temming, H. Ten Kate, P. K. Teng, Y. D. Tennenbaum-Katan, S. Terada, K. Terashi, J. Terron, M. Terwort, M. Testa, R. J. Teuscher, C. M. Tevlin, J. Thadome, J. Therhaag, T. Theveneaux-Pelzer, M. Thioye, S. Thoma, J. P. Thomas, E. N. Thompson, P. D. Thompson, P. D. Thompson, A. S. Thompson, E. Thomson, M. Thomson, R. P. Thun, T. Tic, V. O. Tikhomirov, Y. A. Tikhonov, C. J. W. P. Timmermans, P. Tipton, F. J. Tique Aires Viegas, S. Tisserant, J. Tobias, B. Toczek, T. Todorov, S. Todorova-Nova, B. Toggerson, J. Tojo, S. Tokár, K. Tokunaga, K. Tokushuku, K. Tollefson, M. Tomoto, L. Tompkins, K. Toms, A. Tonazzo, G. Tong, A. Tonoyan, C. Topfel, N. D. Topilin, I. Torchiani, E. Torrence, E. Torró Pastor, J. Toth, F. Touchard, D. R. Tovey, D. Traynor, T. Trefzger, J. Treis, L. Tremblet, A. Tricoli, I. M. Trigger, S. Trincaz-Duvoid, T. N. Trinh, M. F. Tripiana, N. Triplett, W. Trischuk, A. Trivedi, B. Trocmé, C. Troncon, M. Trottier-McDonald, A. Trzupek, C. Tsarouchas, J. C-L. Tseng, M. Tsiakiris, P. V. Tsiareshka, D. Tsionou, G. Tsipolitis, V. Tsiskaridze, E. G. Tskhadadze, I. I. Tsukerman, V. Tsulaia, J.-W. Tsung, S. Tsuno, D. Tsybychev, A. Tua, J. M. Tuggle, M. Turala, D. Turecek, I. Turk Cakir, E. Turlay, P. M. Tuts, A. Tykhonov, M. Tylmad, M. Tyndel, D. Typaldos, H. Tyrvainen, G. Tzanakos, K. Uchida, I. Ueda, R. Ueno, M. Ugland, M. Uhlenbrock, M. Uhrmacher, F. Ukegawa, G. Unal, D. G. Underwood, A. Undrus, G. Unel, Y. Unno, D. Urbaniec, E. Urkovsky, P. Urquijo, P. Urrejola, G. Usai, M. Uslenghi, L. Vacavant, V. Vacek, B. Vachon, S. Vahsen, C. Valderanis, J. Valenta, P. Valente, S. Valentinetti, S. Valkar, E. Valladolid Gallego, S. Vallecorsa, J. A. Valls Ferrer, H. van der Graaf, E. van der Kraaij, E. van der Poel, D. van der Ster, B. Van Eijk, N. van Eldik, P. van Gemmeren, Z. van Kesteren, I. van Vulpen, W. Vandelli, G. Vandoni, A. Vaniachine, P. Vankov, F. Vannucci, F. Varela Rodriguez, R. Vari, E. W. Varnes, D. Varouchas, A. Vartapetian, K. E. Varvell, V. I. Vassilakopoulos, F. Vazeille, G. Vegni, J. J. Veillet, C. Vellidis, F. Veloso, R. Veness, S. Veneziano, A. Ventura, D. Ventura, S. Ventura, M. Venturi, N. Venturi, V. Vercesi, M. Verducci, W. Verkerke, J. C. Vermeulen, L. Vertogardov, A. Vest, M. C. Vetterli, I. Vichou, T. Vickey, G. H. A. Viehhauser, S. Viel, M. Villa, M. Villaplana Perez, E. Vilucchi, M. G. Vincter, E. Vinek, V. B. Vinogradov, M. Virchaux, S. Viret, J. Virzi, A. Vitale, O. Vitells, I. Vivarelli, F. Vives Vaque, S. Vlachos, M. Vlasak, N. Vlasov, A. Vogel, P. Vokac, M. Volpi, G. Volpini, H. von der Schmitt, J. von Loeben, H. von Radziewski, E. von Toerne, V. Vorobel, A. P. Vorobiev, V. Vorwerk, M. Vos, R. Voss, T. T. Voss, J. H. Vossebeld, A. S. Vovenko, N. Vranjes, M. Vranjes Milosavljevic, V. Vrba, M. Vreeswijk, T. Vu Anh, R. Vuillermet, I. Vukotic, W. Wagner, P. Wagner, H. Wahlen, J. Wakabayashi, J. Walbersloh, S. Walch, J. Walder, R. Walker, W. Walkowiak, R. Wall, P. Waller, C. Wang, H. Wang, J. Wang, J. C. Wang, S. M. Wang, A. Warburton, C. P. Ward, M. Warsinsky, P. M. Watkins, A. T. Watson, M. F. Watson, G. Watts, S. Watts, A. T. Waugh, B. M. Waugh, J. Weber, M. Weber, M. S. Weber, P. Weber, A. R. Weidberg, J. Weingarten, C. Weiser, H. Wellenstein, P. S. Wells, M. Wen, T. Wenaus, S. Wendler, Z. Weng, T. Wengler, S. Wenig, N. Wermes, M. Werner, P. Werner, M. Werth, M. Wessels, K. Whalen, S. J. Wheeler-Ellis, S. P. Whitaker, A. White, M. J. White, S. White, S. R. Whitehead, D. Whiteson, D. Whittington, F. Wicek, D. Wicke, F. J. Wickens, W. Wiedenmann, M. Wielers, P. Wienemann, C. Wiglesworth, L. A. M. Wiik, A. Wildauer, M. A. Wildt, I. Wilhelm, H. G. Wilkens, J. Z. Will, E. Williams, H. H. Williams, W. Willis, S. Willocq, J. A. Wilson, M. G. Wilson, A. Wilson, I. Wingerter-Seez, S. Winkelmann, F. Winklmeier, M. Wittgen, M. W. Wolter, H. Wolters, G. Wooden, B. K. Wosiek, J. Wotschack, M. J. Woudstra, K. Wraight, C. Wright, B. Wrona, S. L. Wu, X. Wu, Y. Wu, E. Wulf, R. Wunstorf, B. M. Wynne, L. Xaplanteris, S. Xella, S. Xie, Y. Xie, C. Xu, D. Xu, G. Xu, B. Yabsley, M. Yamada, A. Yamamoto, K. Yamamoto, S. Yamamoto, T. Yamamura, J. Yamaoka, T. Yamazaki, Y. Yamazaki, Z. Yan, H. Yang, S. Yang, U. K. Yang, Y. Yang, Y. Yang, Z. Yang, S. Yanush, W-M. Yao, Y. Yao, Y. Yasu, J. Ye, S. Ye, M. Yilmaz, R. Yoosoofmiya, K. Yorita, R. Yoshida, C. Young, S. Youssef, D. Yu, J. Yu, J. Yu, L. Yuan, A. Yurkewicz, V. G. Zaets, R. Zaidan, A. M. Zaitsev, Z. Zajacova, Yo. K. Zalite, L. Zanello, P. Zarzhitsky, A. Zaytsev, M. Zdrazil, C. Zeitnitz, M. Zeller, P. F. Zema, A. Zemla, C. Zendler, A. V. Zenin, O. Zenin, T. Ženiš, Z. Zenonos, S. Zenz, D. Zerwas, G. Zevi della Porta, Z. Zhan, D. Zhang, H. Zhang, J. Zhang, X. Zhang, Z. Zhang, L. Zhao, T. Zhao, Z. Zhao, A. Zhemchugov, S. Zheng, J. Zhong, B. Zhou, N. Zhou, Y. Zhou, C. G. Zhu, H. Zhu, Y. Zhu, X. Zhuang, V. Zhuravlov, D. Zieminska, B. Zilka, R. Zimmermann, S. Zimmermann, S. Zimmermann, M. Ziolkowski, R. Zitoun, L. Živković, V. V. Zmouchko, G. Zobernig, A. Zoccoli, Y. Zolnierowski, A. Zsenei, M. zur Nedden, V. Zutshi, L. Zwalinski

Subjects
Nuclear and High Energy Physics, Physics and Astronomy (miscellaneous), High Energy Physics::Experiment, +10+GeV%29%3A+Inclusive+production+with+identified+leptons+photons+or+other+nonhadronic+particles%22">Hadron-induced high- and super-high-energy interactions (energy > 10 GeV): Inclusive production with identified leptons photons or other nonhadronic particles
Abstract

A measurement of the cross section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy √s=7 TeV is presented. The measurement covers the pseudorapidity ranges |ηγ

Published
2011

32. Mechanism of an animal toxin-antidote system.

Author

Caro L, Wei AD, Thomas CA, Posch G, Uremis A, Franzi MC, Abell SJ, Laszlo AH, Gundlach JH, Ramirez JM, and Ailion M

Abstract

Toxin-antidote systems are selfish genetic elements composed of a linked toxin and antidote. The peel-1 zeel-1 toxin-antidote system in C. elegans consists of a transmembrane toxin protein PEEL-1 which acts cell autonomously to kill cells. Here we investigate the molecular mechanism of PEEL-1 toxicity. We find that PEEL-1 requires a small membrane protein, PMPL-1, for toxicity. Together, PEEL-1 and PMPL-1 are sufficient for toxicity in a heterologous system, HEK293T cells, and cause cell swelling and increased cell permeability to monovalent cations. Using purified proteins, we show that PEEL-1 and PMPL-1 allow ion flux through lipid bilayers and generate currents which resemble ion channel gating. Our work suggests that PEEL-1 kills cells by co-opting PMPL-1 and creating a cation channel., Competing Interests: Competing interests: Authors declare no competing interests.

Published
2024
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33. Mutations in the NXF-1:NXT-1 mRNA export complex affect gene-expression driven by the hsp-16.41 promoter.

Author

Crawford MW, Posch G, Cattin-Ortolá J, Topalidou I, and Ailion M

Abstract

The NXF-1 : NXT-1 heterodimer is essential for the nuclear export of mRNA. Here we describe three new alleles of nxf-1 and one allele of nxt-1 isolated from a forward genetic screen. These mutations cause no apparent phenotype under normal growth conditions, but partially suppress the lethality caused by heat-shock induced expression of the PEEL-1 toxin from P hsp-16.41 :: peel-1 . There is also decreased expression of P hsp-16.41 ::eGFP in an nxf-1 mutant. We propose that NXF-1 : NXT-1 influences the expression of heat-shock activated genes due to a role in the recruitment of the hsp-16.41 promoter to the nuclear pore complex during heat-shock., Competing Interests: The authors declare that there are no conflicts of interest present., (Copyright: © 2023 by the authors.)

Published
2023
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34. Melanic pigmentation and light preference within and between two Drosophila species.

Author

Cooley AM, Schmitz S, Cabrera EJ, Cutter M, Sheffield M, Gingerich I, Thomas G, Lincoln CNM, Moore VH, Moore AE, Davidson SA, Lonberg N, Fournier EB, Love SM, Posch G, Bihrle MB, Mayer SD, Om K, Wilson L, Doe CQ, Vincent CE, Wong ERT, Wall I, Wicks J, and Roberts S

Abstract

Environmental adaptation and species divergence often involve suites of co-evolving traits. Pigmentation in insects presents a variable, adaptive, and well-characterized class of phenotypes for which correlations with multiple other traits have been demonstrated. In Drosophila , the pigmentation genes ebony and tan have pleiotropic effects on flies' response to light, creating the potential for correlated evolution of pigmentation and vision. Here, we investigate differences in light preference within and between two sister species, Drosophila americana and D. novamexicana , which differ in pigmentation in part because of evolution at ebony and tan and occupy environments that differ in many variables including solar radiation. We hypothesized that lighter pigmentation would be correlated with a greater preference for environmental light and tested this hypothesis using a habitat choice experiment. In a first set of experiments, using males of D. novamexicana line N14 and D. americana line A00, the light-bodied D. novamexicana was found slightly but significantly more often than D. americana in the light habitat. A second experiment, which included additional lines and females as well as males, failed to find any significant difference between D. novamexicana -N14 and D. americana -A00. Additionally, the other dark line of D. americana (A04) was found in the light habitat more often than the light-bodied D. novamexicana -N14, in contrast to our predictions. However, the lightest line of D. americana , A01, was found substantially and significantly more often in the light habitat than the two darker lines of D. americana , thus providing partial support for our hypothesis. Finally, across all four lines, females were found more often in the light habitat than their more darkly pigmented male counterparts. Additional replication is needed to corroborate these findings and evaluate conflicting results, with the consistent effect of sex within and between species providing an especially intriguing avenue for further research., Competing Interests: None declared., (© 2021 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd.)

Published
2021
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35. Structure and immunogenicity of the rough-type lipopolysaccharide from the periodontal pathogen Tannerella forsythia.

Author

Posch G, Andrukhov O, Vinogradov E, Lindner B, Messner P, Holst O, and Schäffer C

Subjects
Bacteroidetes isolation & purification, Cell Line, Cytokines metabolism, Humans, Macrophages drug effects, Macrophages immunology, Magnetic Resonance Spectroscopy, Mass Spectrometry, Periodontitis microbiology, Bacteroidetes chemistry, Bacteroidetes immunology, Lipopolysaccharides chemistry, Lipopolysaccharides immunology
Abstract

Tannerella forsythia is a Gram-negative anaerobic organism that inhabits subgingival plaque biofilms and is covered with a so far unique surface layer composed of two glycoproteins. It belongs to the so-called "red complex" of bacteria comprising species that are associated with periodontal disease. While the surface layer glycoprotein glycan structure had been elucidated recently and found to be a virulence factor, no structural data on the lipopolysaccharide (LPS) of this organism were available. In this study, the T. forsythia LPS structure was partially elucidated by a combined mass spectrometry (MS) and nuclear magnetic resonance spectroscopy (NMR) approach and initial experiments to characterize its immunostimulatory potential were performed. The T. forsythia LPS is a complex, rough-type LPS with a core region composed of one 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) residue, three mannose residues, and two glucosamine residues. MS analyses of O-deacylated LPS proved that, in addition, one phosphoethanolamine residue and most likely one galactose-phosphate residue were present, however, their positions could not be identified. Stimulation of human macrophages with T. forsythia LPS resulted in the production of the proinflammatory cytokines interleukin-1 (IL-1), IL-6, and tumor necrosis factor alpha in a dose-dependent manner. The response to T. forsythia LPS was observed only upon stimulation in the presence of fetal calf serum (FCS), whereas no cytokine production was observed in the absence of FCS. This finding suggests that the presence of certain additional cofactors is crucial for the immune response induced by T. forsythia LPS.

Published
2013
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36. "Cross-glycosylation" of proteins in Bacteroidales species.

Author

Posch G, Pabst M, Neumann L, Coyne MJ, Altmann F, Messner P, Comstock LE, and Schäffer C

Subjects
Bacterial Proteins chemistry, Bacteroides chemistry, Carbohydrate Sequence, Glycoproteins chemistry, Glycosylation, Molecular Sequence Data, Oligosaccharides chemistry, Polysaccharides chemistry, Polysaccharides metabolism, Bacterial Proteins metabolism, Bacteroides metabolism, Glycoproteins metabolism
Abstract

While it is now evident that the two Bacteroidales species Bacteroides fragilis and Tannerella forsythia both have general O-glycosylation systems and share a common glycosylation sequon, the ability of these organisms to glycosylate a protein native to the other organism has not yet been demonstrated. Here, we report on the glycosylation of heterologous proteins between these two organisms. Using genetic tools previously developed for Bacteroides species, two B. fragilis model glycoproteins were expressed in the fastidious anaerobe T. forsythia and the attachment of the known T. forsythia O-glycan to these proteins was demonstrated by liquid chromatography electrospray ionization tandem mass spectrometry. Likewise, two predominant T. forsythia glycoproteins were expressed in B. fragilis and glycosylation with the B. fragilis O-glycan was confirmed. Purification of these proteins from B. fragilis allowed the preliminary characterization of the previously uncharacterized B. fragilis protein O-glycan. Based on mass spectrometric data, we show that the B. fragilis protein O-glycan is an oligosaccharide composed of nine sugar units. Compositional and structural similarities with the T. forsythia O-glycan suggest commonalities in their biosynthesis. These data demonstrate the feasibility of exploiting these organisms for the design of novel glycoproteins.

Published
2013
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37. Phylum-wide general protein O-glycosylation system of the Bacteroidetes.

Author

Coyne MJ, Fletcher CM, Chatzidaki-Livanis M, Posch G, Schaffer C, and Comstock LE

Subjects
Conserved Sequence, Genes, Bacterial, Glycosylation, Metabolic Networks and Pathways, Bacterial Proteins metabolism, Bacteroidetes genetics, Bacteroidetes metabolism, Glycoproteins metabolism, Polysaccharides metabolism
Abstract

The human gut symbiont Bacteroides fragilis has a general protein O-glycosylation system in which numerous extracytoplasmic proteins are glycosylated at a three amino acid motif. In B. fragilis, protein glycosylation is a fundamental and essential property as mutants with protein glycosylation defects have impaired growth and are unable to competitively colonize the mammalian intestine. In this study, we analysed the phenotype of B. fragilis mutants with defective protein glycosylation and found that the glycan added to proteins is comprised of a core glycan and an outer glycan. The genetic region encoding proteins for the synthesis of the outer glycan is conserved within a Bacteroides species but divergent between species. Unlike the outer glycan, an antiserum raised to the core glycan reacted with all Bacteroidetes species tested, from all four classes of the phylum. We found that diverse Bacteroidetes species synthesize numerous glycoproteins and glycosylate proteins at the same three amino acid motif. The wide-spread conservation of this protein glycosylation system within the phylum suggests that this system of post-translational protein modification evolved early, before the divergence of the four classes of Bacteroidetes, and has been maintained due to its physiological importance to the diverse species of this phylum., (© 2013 John Wiley & Sons Ltd.)

Published
2013
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38. Glycobiology Aspects of the Periodontal Pathogen Tannerella forsythia.

Author

Posch G, Sekot G, Friedrich V, Megson ZA, Koerdt A, Messner P, and Schäffer C

Abstract

Glycobiology is important for the periodontal pathogen Tannerella forsythia, affecting the bacterium's cellular integrity, its life-style, and virulence potential. The bacterium possesses a unique Gram-negative cell envelope with a glycosylated surface (S-) layer as outermost decoration that is proposed to be anchored via a rough lipopolysaccharide. The S-layer glycan has the structure 4‑MeO-b-ManpNAcCONH2-(1→3)-[Pse5Am7Gc-(2→4)-]-b-ManpNAcA-(1→4)-[4-MeO-a-Galp-(1→2)-]-a-Fucp-(1→4)-[-a-Xylp-(1→3)-]-b-GlcpA-(1→3)-[-b-Digp-(1→2)-]-a-Galp and is linked to distinct serine and threonine residues within the D(S/T)(A/I/L/M/T/V) amino acid motif. Also several other Tannerella proteins are modified with the S‑layer oligosaccharide, indicating the presence of a general O‑glycosylation system. Protein O‑glycosylation impacts the life-style of T. forsythia since truncated S-layer glycans present in a defined mutant favor biofilm formation. While the S‑layer has also been shown to be a virulence factor and to delay the bacterium's recognition by the innate immune system of the host, the contribution of glycosylation to modulating host immunity is currently unraveling. Recently, it was shown that Tannerella surface glycosylation has a role in restraining the Th17-mediated neutrophil infiltration in the gingival tissues. Related to its asaccharolytic physiology, T. forsythia expresses a robust enzymatic repertoire, including several glycosidases, such as sialidases, which are linked to specific growth requirements and are involved in triggering host tissue destruction. This review compiles the current knowledge on the glycobiology of T. forsythia.

Published
2012
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39. Analysis of the cell surface layer ultrastructure of the oral pathogen Tannerella forsythia.

Author

Sekot G, Posch G, Oh YJ, Zayni S, Mayer HF, Pum D, Messner P, Hinterdorfer P, and Schäffer C

Subjects
Bacterial Proteins genetics, Bacteroidetes genetics, Bacteroidetes pathogenicity, Cloning, Molecular, Membrane Glycoproteins genetics, Microscopy, Atomic Force, Microscopy, Electron, Transmission, Transcription, Genetic, Virulence, Bacterial Proteins chemistry, Bacteroidetes ultrastructure, Cell Membrane ultrastructure, Membrane Glycoproteins chemistry
Abstract

The Gram-negative oral pathogen Tannerella forsythia is decorated with a 2D crystalline surface (S-) layer, with two different S-layer glycoprotein species being present. Prompted by the predicted virulence potential of the S-layer, this study focused on the analysis of the arrangement of the individual S-layer glycoproteins by a combination of microscopic, genetic, and biochemical analyses. The two S-layer genes are transcribed into mRNA and expressed into protein in equal amounts. The S-layer was investigated on intact bacterial cells by transmission electron microscopy, by immune fluorescence microscopy, and by atomic force microscopy. The analyses of wild-type cells revealed a distinct square S-layer lattice with an overall lattice constant of 10.1 ± 0.7 nm. In contrast, a blurred lattice with a lattice constant of 9.0 nm was found on S-layer single-mutant cells. This together with in vitro self-assembly studies using purified (glyco)protein species indicated their increased structural flexibility after self-assembly and/or impaired self-assembly capability. In conjunction with TEM analyses of thin-sectioned cells, this study demonstrates the unusual case that two S-layer glycoproteins are co-assembled into a single S-layer. Additionally, flagella and pilus-like structures were observed on T. forsythia cells, which might impact the pathogenicity of this bacterium.

Published
2012
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40. Characterization and scope of S-layer protein O-glycosylation in Tannerella forsythia.

Author

Posch G, Pabst M, Brecker L, Altmann F, Messner P, and Schäffer C

Subjects
Cell Membrane metabolism, Chromatography, Liquid methods, Genome, Bacterial, Glycopeptides chemistry, Glycosylation, Magnetic Resonance Spectroscopy, Monosaccharides chemistry, Proteomics methods, Spectrometry, Mass, Electrospray Ionization methods, Surface Properties, Tandem Mass Spectrometry methods, Virulence, Bacteroides metabolism, Membrane Glycoproteins chemistry
Abstract

Cell surface glycosylation is an important element in defining the life of pathogenic bacteria. Tannerella forsythia is a Gram-negative, anaerobic periodontal pathogen inhabiting the subgingival plaque biofilms. It is completely covered by a two-dimensional crystalline surface layer (S-layer) composed of two glycoproteins. Although the S-layer has previously been shown to delay the bacterium's recognition by the innate immune system, we characterize here the S-layer protein O-glycosylation as a potential virulence factor. The T. forsythia S-layer glycan was elucidated by a combination of electrospray ionization-tandem mass spectrometry and nuclear magnetic resonance spectroscopy as an oligosaccharide with the structure 4-Me-β-ManpNAcCONH(2)-(1→3)-[Pse5Am7Gc-(2→4)-]-β-ManpNAcA-(1→4)-[4-Me-α-Galp-(1→2)-]-α-Fucp-(1→4)-[-α-Xylp-(1→3)-]-β-GlcpA-(1→3)-[-β-Digp-(1→2)-]-α-Galp, which is O-glycosidically linked to distinct serine and threonine residues within the three-amino acid motif (D)(S/T)(A/I/L/M/T/V) on either S-layer protein. This S-layer glycan obviously impacts the life style of T. forsythia because increased biofilm formation of an UDP-N-acetylmannosaminuronic acid dehydrogenase mutant can be correlated with the presence of truncated S-layer glycans. We found that several other proteins of T. forsythia are modified with that specific oligosaccharide. Proteomics identified two of them as being among previously classified antigenic outer membrane proteins that are up-regulated under biofilm conditions, in addition to two predicted antigenic lipoproteins. Theoretical analysis of the S-layer O-glycosylation of T. forsythia indicates the involvement of a 6.8-kb gene locus that is conserved among different bacteria from the Bacteroidetes phylum. Together, these findings reveal the presence of a protein O-glycosylation system in T. forsythia that is essential for creating a rich glycoproteome pinpointing a possible relevance for the virulence of this bacterium.

Published
2011
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41. Evaluation of different expression systems for the heterologous expression of pyranose 2-oxidase from Trametes multicolor in E. coli.

Author

Spadiut O, Posch G, Ludwig R, Haltrich D, and Peterbauer CK

Subjects
Carbohydrate Dehydrogenases metabolism, Culture Techniques, Escherichia coli growth & development, Escherichia coli metabolism, Fungal Proteins metabolism, Genetic Vectors genetics, Genetic Vectors metabolism, Carbohydrate Dehydrogenases genetics, Escherichia coli genetics, Fungal Proteins genetics, Gene Expression, Genetic Engineering methods, Trametes enzymology
Abstract

The heterologous production of the industrially relevant fungal enzyme pyranose 2-oxidase in the prokaryotic host E. coli was investigated using 3 different expression systems, i.e. the well-studied T7 RNA polymerase based pET21d+, the L-arabinose inducible pBAD and the pCOLD system. Preliminary experiments were done in shaking flasks at 25 degrees C and optimized induction conditions to compare the productivity levels of the different expression systems. The pET21d+ and the pCOLD system gave 29 U/L x h and 14 U/L x h of active pyranose 2-oxidase, respectively, whereas the pBAD system only produced 6 U/L x h. Process conditions for batch fermentations were optimized for the pET21d+ and the pCOLD systems in order to reduce the formation of inactive inclusion bodies. The highest productivity rate with the pET21d+ expression system in batch fermentations was determined at 25 degrees C with 32 U/L x h. The pCOLD system showed the highest productivity rate (19 U/L x h) at 25 degrees C and induction from the start of the cultivation. Using the pCOLD system in a fed batch fermentation at 25 degrees C with a specific growth rate of mu = 0.15 h-1resulted in the highest productivity rate of active pyranose oxidase with 206 U/L x h.

Published
2010
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42. Biomedical evidence of influence of geopathic zones on the human body: scientifically traceable effects and ways of harmonization.

Author

Hacker GW, Pawlak E, Pauser G, Tichy G, Jell H, Posch G, Kraibacher G, Aigner A, and Hutter J

Subjects
Adolescent, Adult, Aged, Double-Blind Method, Electromagnetic Fields, Energy Metabolism physiology, Evidence-Based Medicine, Female, Humans, Immune System physiopathology, Male, Meridians, Middle Aged, Pineal Gland physiopathology, Reproducibility of Results, Stress, Physiological physiopathology, Biophysics methods, Complementary Therapies methods, Geography, Stress, Physiological etiology
Abstract

Background: Empiric knowledge of the existence of geopathic zones ('water veins' etc) is probably as old as humankind. It has often been tried to experimentally detect direct influences on the body. However, so far, there have been no publications in accepted biomedical journals. The target of this study was to verify influences of 2 different zones above ground on the human body and to test a device for which pilot studies have indicated a potential harmonizing effect in this context., Materials and Methods: Using a randomized, non-clinical, double-blinded trial design, 52 persons were tested with a gas discharge visualization (GDV) system whilst staying on 2 zones with or without the Geowave device (Geowave-Research, Salzburg, Austria). The 2 zones investigated had been dowsed by experienced professional dowsers and labeled with black dots in a non-persuasive manner, thereby blindly representing areas of geopathy or more neutral zones. The main analytical parameter was the GDV glow image area (area of glow). Complementary calculated parameters were spatial fractality, corona projections and corona diagrams., Results: In the geopathic zone, the detected areas of glow were statistically significantly smaller than in the more neutral zone. With the Geowave blindly mounted in an adjacent room of the above story, a marked increase of the glow image area was found in both zones. The corona projections showed well-recognizable points of body energy deficits in the geopathic zone, mostly associated with the lymphatic system, the cardiovascular system and the pineal gland, which were -- to a distinctly lesser degree -- also present in the more neutral zone. The device tested yielded compensation or harmonization in both zones in most of the test persons., Conclusion: The significant differences in the physical area of glow parameter, which were also noticed for the complementary parameters analyzed, lead to the conclusion that the 2 different zones within the same room (geopathic vs. more neutral zone) exerted different influences on the human body, which may have caused a geopathic stress phenomenon. As a result, individually different retardation of the immune system and other organs may occur. The device tested in both zones showed harmonizing effects, which may help to compensate some influences of geopathy and possibility also superimposed stressors derived from certain other sources, such as technical electromagnetic fields.

Published
2005
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43. [Characteristics of the heart rate of emergency physicians in emergency helicopters].

Author

Benzer A, Niebergall H, Posch G, and Flora G

Subjects
Adult, Humans, Aircraft, Emergency Medical Services, Heart Rate, Physicians psychology
Abstract

The heart rate behaviour of 14 emergency doctors was examined in 50 cases of medical emergency service by helicopter. In addition, the subjective stress experienced by the probands was inquired by means of a questionnaire. The alarm and the landing at the site of the emergency resulted in the most marked heart rate increases; also during the period of approaching the patient, his rescue and care, persistent tachycardia could be observed. Recovery began slowly during the return flight, but even 15 minutes after completion of the emergency task the heart rate was still higher than the original value before the alarm had been sounded. Subjectively the total stress was considered to be generally low in the opinion of the emergency doctors. It seems that unconscious mechanisms of repression prevent the actual realistic recording of physical and emotional stress during the emergency service by helicopter.

Published
1991
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44. [Lesion of the brachial plexus, caused by wrong positioning during surgery].

Author

Mitterschiffthaler G, Theiner A, Posch G, Jäger-Lackner E, and Fuith LC

Subjects
Adult, Female, Humans, Hysterectomy, Lipoma surgery, Male, Middle Aged, Thoracic Neoplasms surgery, Thyroid Neoplasms surgery, Thyroidectomy, Uterine Neoplasms surgery, Anesthesia, General, Brachial Plexus injuries, Postoperative Complications etiology, Posture
Abstract

We report three patients, which showed plexus palsies after routine operations. Compression and stretch of the nerves despite pads leaded to nerve injury in patient A. Abduction of the arm, fixed wrist, hypotension in steep Trendelenburg position and a preexisting shoulder-arm-syndrome were the causes in patient B. Hyperreclination of the head in semisitting position caused the lesion in patient C. The anaesthetist should know the risks of positioning to prevent nerve injuries.

Published
1987

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