48 results on '"Pilipenko, T."'
Search Results
2. New educational technologies as a means of cross - regional cooperation in the field of food raw material and product safety control
- Author
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Bazarnova J G, Zhilinskaya N T, Pilipenko T V, Belokurova E S, Ivanchenko O B, and Loboda V V
- Subjects
Environmental sciences ,GE1-350 - Abstract
International e-learning resource in the field of food product quality and veterinary disease control based on Government requirements of the European Union and Eurasian Economic Union has been created and tested. This resource consists of the one general professional cycle and five professional modules, about 60% of them are in distance e-learning format. The modularity of the educational resource allows the employer or students to choose a training program format, as well as the amount of distance learning or classroom training hours for different groups of specialists in the field of food quality and veterinary control: chiefs of quality control center or laboratories, veterinarians, microbiologists, specialists of veterinary diagnostics laboratories, chemical engineers. The involvement of participants from EU and EEU-countries in the educational process is important for the development of interregional and international activities, the creation of the unified legal framework in the field of food security in many countries.
- Published
- 2020
- Full Text
- View/download PDF
3. Mathematical modeling of flow hydraulics as a result of the development of the NSM channel open pit (on the example of the Tom river)
- Author
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Pilipenko, T, primary, Mikhailova, T, additional, and Panov, D, additional
- Published
- 2021
- Full Text
- View/download PDF
4. Assessment of the position of the project water flow in the lower reaches of hydroelectric facilities, using the example of the novosibirsk hydroelectric power station
- Author
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Akhmatova, N, primary, Mikhaylova, T, additional, and Pilipenko, T, additional
- Published
- 2021
- Full Text
- View/download PDF
5. Improvement of methods of hydrological forecasting using geoinformation technologies
- Author
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Zueva, A, primary, Shamova, V, additional, and Pilipenko, T, additional
- Published
- 2021
- Full Text
- View/download PDF
6. Сучасні підходи до застосування мінеральних добрив за збереження грунтової родючості в умовах зміни клімату
- Author
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Гамаюнова, В. В., Gamayunova, V., Хоненко, Л. Г., Khonenko, L., Бакланова, Т. В., Baklanova, T., Коваленко, О. А., Kovalenko, O., Пилипенко, Т. В., Pilipenko, T., Гамаюнова, В. В., Gamayunova, V., Хоненко, Л. Г., Khonenko, L., Бакланова, Т. В., Baklanova, T., Коваленко, О. А., Kovalenko, O., Пилипенко, Т. В., and Pilipenko, T.
- Abstract
В статті зазначено, що найкращі у світі, за потенціалом родючості, ґрунти України і, перш за все, чорноземи, останнім часом, внаслідок відхилення технологій від загальноприйнятих розроблених зональних рекомендацій та порушення основних законів землеробства, істотно втрачають основні показники родючості. Погіршується їх структура, зменшується вміст гумусу, органічної речовини, макро- та мікроелементів. Зазначене несприятливо позначається на продуктивності сільськогосподарських культур, що особливо проявляється як у зоні Південного Степу, так і загалом в Україні, у т. ч. й у зв’язку зі змінами кліматичних умов. Рівень урожайності сільськогосподарських рослин, у першу чергу, лімітує забезпеченість їх вологою, яка без оптимального вмісту органічної речовини ґрунтом не утримується, швидко втрачається на непродуктивне випаровування, а не на формування продуктивності. Друге місце серед факторів, що найбільшою мірою впливають на ріст і розвиток рослин, займає живлення. Найкращі умови забезпечення рослин поживними речовинами створюються за органо-мінеральної системи удобрення. Їх доцільно вносити сумісно у науково обґрунтованих нормах. За таких умов застосування добрив найбільш повно зберігаються існуючі параметри родючості ґрунту та навіть покращуються й особливо за обґрунтованого чергування сільськогосподарських культур у сівозміні. Разом з тим, в останні десятиліття суттєво зменшено обсяги внесення органіки, що негативно позначається на стані родючості ґрунтів. При цьому, виникає нагальна потреба у найбільш доцільному застосуванні мінеральних добрив, доборі їх видів, форм і співвідношень для збільшення врожайності та основних показників якості сільськогосподарських культур. Мінеральні добрива слід добирати з урахуванням зростання посушливості зони, з тим, щоб незалежно від рівня зволоження, вони поглиналися ґрунтом, рівномірно розподілялися у ньому та ефективно використовувалися рослинами. Разом з тим, внесені добрива повинні добре позначатися на основних показниках родюч, In article it is specified that the first in potentials of fertility soil of Ukraine and first of all chernozems, in recent years owing to a deviation of technologies from it is general the accepted developed zone recommendations and violation of fundamental laws of agriculture, key indicators of fertility significantly lose. Their structure worsens, the maintenance of a humus, organic matter, macro - and minerals decreases. Specified adversely affects productivity of crops that it is especially shown as in a zone of the southern steppe, and in general in Ukraine including due to changes of climatic conditions. Level of productivity of agricultural plants first of all limits security with their moisture which without the optimum content of organic matter by the soil does not keep, is quickly lost on unproductively evaporations, but not on formation of productivity. That most influences growth and development of plants, occupies the second place among factors food. The best conditions of providing plants with nutrients are created on body of a mineral system of fertilizer. It is expedient to bring them compatibly in evidence-based norms. Under such circumstances use of fertilizers most fully remains the existing parameters of fertility of the soil and even improves and especially for proved watch of crops in a crop rotation. At the same time in the last decades volumes of introduction of organic chemistry are significantly reduced that negatively affects a condition of fertility of soils. At the same time there is an urgent need for the most expedient use of mineral fertilizers, selection of their types, forms and ratios for increase in productivity and key indicators of quality of crops. Mineral fertilizers it is necessary to gather additionally taking into account growth of dryness of a zone irrespective of moistening level, they were absorbed by the soil, were evenly distributed in it and were effectively used by plants. At the same time fertilizers are introduced, В статье указано, что лучшие в мире, по потенциалу плодородия, почвы Украины и, прежде всего, черноземы, в последнее время, вследствие отклонения технологий от общепринятых разработанных зональных рекомендаций и нарушений основных законов земледелия, существенно теряют основные показатели плодородия. Ухудшается их структура, уменьшается содержание гумуса, органического вещества, макро- и микроэлементов. Указанное неблагоприятно сказывается на продуктивности сельскохозяйственных культур, что особенно проявляется как в зоне Южной Степи, так и в целом по Украине, в т. ч. и в связи с изменениями климатических условий. Уровень урожайности сельскохозяйственных растений, в первую очередь, лимитирует обеспеченность их влагой, которая без оптимального содержания органического вещества грунтом не содержится, быстро теряется в непродуктивном испарении, а не на формирование продуктивности. Второе место среди факторов, которые в наибольшей степени влияют на рост и развитие растений, занимает питание. Лучшие условия обеспечения растений питательными веществами создаются при органо-минеральной системе удобрения. Их целесообразно вносить в научно обоснованных нормах. При таких условиях применения удобрений наиболее полно сохраняются существующие параметры плодородия почвы и даже улучшаются, особенно при обоснованном чередовании сельскохозяйственных культур в севообороте. Вместе с тем, в последние десятилетия существенно уменьшены объемы внесения органики, что отрицательно сказывается на состоянии плодородия почв. При этом, возникает настоятельная потребность в наиболее целесообразном применении минеральных удобрений, подборе их видов, форм и соотношений для увеличения урожайности и основных показателей качества сельскохозяйственных культур. Минеральные удобрения следует подбирать с учетом роста засухи зоны, с тем, чтобы независимо от уровня увлажнения, они поглощались почвой, равномерно распределялись в ней и эффективно использовались растениями. Вместе с тем, внесенные удобрения д
- Published
- 2021
7. A study of the effect of metal corrosion inhibitors on the hydrogenation of steel and changes in its plasticity upon etching in sulfuric acid solutions
- Author
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Pilipenko, T. N. and Efimova, V. G.
- Published
- 2012
- Full Text
- View/download PDF
8. Сучасні підходи до застосування мінеральних добрив за збереження грунтової родючості в умовах зміни клімату
- Author
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Gamayunova, V., Khonenko, L., Baklanova, T., Kovalenko, O., and Pilipenko, T.
- Subjects
body mineral system to fertilizer ,тверді та рідкі мінеральні добрива ,efficiency of fertilizer ,fertility of the soil ,зміна клімату ,изменение климата ,solid and liquid mineral fertilizers ,органо-мінеральна система удобрення ,твердые и жидкие минеральные удобрения ,плодородие почвы ,ефективність удобрення ,эффективность удобрения ,climate change ,органо-минеральная система удобрения ,родючість ґрунту - Abstract
В статті зазначено, що найкращі у світі, за потенціалом родючості, ґрунти України і, перш за все, чорноземи, останнім часом, внаслідок відхилення технологій від загальноприйнятих розроблених зональних рекомендацій та порушення основних законів землеробства, істотно втрачають основні показники родючості. Погіршується їх структура, зменшується вміст гумусу, органічної речовини, макро- та мікроелементів. Зазначене несприятливо позначається на продуктивності сільськогосподарських культур, що особливо проявляється як у зоні Південного Степу, так і загалом в Україні, у т. ч. й у зв’язку зі змінами кліматичних умов. Рівень урожайності сільськогосподарських рослин, у першу чергу, лімітує забезпеченість їх вологою, яка без оптимального вмісту органічної речовини ґрунтом не утримується, швидко втрачається на непродуктивне випаровування, а не на формування продуктивності. Друге місце серед факторів, що найбільшою мірою впливають на ріст і розвиток рослин, займає живлення. Найкращі умови забезпечення рослин поживними речовинами створюються за органо-мінеральної системи удобрення. Їх доцільно вносити сумісно у науково обґрунтованих нормах. За таких умов застосування добрив найбільш повно зберігаються існуючі параметри родючості ґрунту та навіть покращуються й особливо за обґрунтованого чергування сільськогосподарських культур у сівозміні. Разом з тим, в останні десятиліття суттєво зменшено обсяги внесення органіки, що негативно позначається на стані родючості ґрунтів. При цьому, виникає нагальна потреба у найбільш доцільному застосуванні мінеральних добрив, доборі їх видів, форм і співвідношень для збільшення врожайності та основних показників якості сільськогосподарських культур. Мінеральні добрива слід добирати з урахуванням зростання посушливості зони, з тим, щоб незалежно від рівня зволоження, вони поглиналися ґрунтом, рівномірно розподілялися у ньому та ефективно використовувалися рослинами. Разом з тим, внесені добрива повинні добре позначатися на основних показниках родючості ґрунтів та підтримувати в них позитивний баланс не лише основних елементів живлення, а і гумусу. У статті обґрунтовано, що саме рідкі мінеральні добрива як прості, так і складні, мають певні переваги в ефективності порівняно з більш поширеними у застосуванні видами твердих (сипучих та гранульованих) добрив., In article it is specified that the first in potentials of fertility soil of Ukraine and first of all chernozems, in recent years owing to a deviation of technologies from it is general the accepted developed zone recommendations and violation of fundamental laws of agriculture, key indicators of fertility significantly lose. Their structure worsens, the maintenance of a humus, organic matter, macro - and minerals decreases. Specified adversely affects productivity of crops that it is especially shown as in a zone of the southern steppe, and in general in Ukraine including due to changes of climatic conditions. Level of productivity of agricultural plants first of all limits security with their moisture which without the optimum content of organic matter by the soil does not keep, is quickly lost on unproductively evaporations, but not on formation of productivity. That most influences growth and development of plants, occupies the second place among factors food. The best conditions of providing plants with nutrients are created on body of a mineral system of fertilizer. It is expedient to bring them compatibly in evidence-based norms. Under such circumstances use of fertilizers most fully remains the existing parameters of fertility of the soil and even improves and especially for proved watch of crops in a crop rotation. At the same time in the last decades volumes of introduction of organic chemistry are significantly reduced that negatively affects a condition of fertility of soils. At the same time there is an urgent need for the most expedient use of mineral fertilizers, selection of their types, forms and ratios for increase in productivity and key indicators of quality of crops. Mineral fertilizers it is necessary to gather additionally taking into account growth of dryness of a zone irrespective of moistening level, they were absorbed by the soil, were evenly distributed in it and were effectively used by plants. At the same time fertilizers are introduced have to affect well key indicators of fertility of soils and to maintain in them positive balance not only basic elements of food, and a humus. In article it is reasonable that liquid mineral fertilizers both simple, and difficult, have certain advantages in efficiency in comparison with types, more widespread in application, firm (loose and granulated) fertilizers., В статье указано, что лучшие в мире, по потенциалу плодородия, почвы Украины и, прежде всего, черноземы, в последнее время, вследствие отклонения технологий от общепринятых разработанных зональных рекомендаций и нарушений основных законов земледелия, существенно теряют основные показатели плодородия. Ухудшается их структура, уменьшается содержание гумуса, органического вещества, макро- и микроэлементов. Указанное неблагоприятно сказывается на продуктивности сельскохозяйственных культур, что особенно проявляется как в зоне Южной Степи, так и в целом по Украине, в т. ч. и в связи с изменениями климатических условий. Уровень урожайности сельскохозяйственных растений, в первую очередь, лимитирует обеспеченность их влагой, которая без оптимального содержания органического вещества грунтом не содержится, быстро теряется в непродуктивном испарении, а не на формирование продуктивности. Второе место среди факторов, которые в наибольшей степени влияют на рост и развитие растений, занимает питание. Лучшие условия обеспечения растений питательными веществами создаются при органо-минеральной системе удобрения. Их целесообразно вносить в научно обоснованных нормах. При таких условиях применения удобрений наиболее полно сохраняются существующие параметры плодородия почвы и даже улучшаются, особенно при обоснованном чередовании сельскохозяйственных культур в севообороте. Вместе с тем, в последние десятилетия существенно уменьшены объемы внесения органики, что отрицательно сказывается на состоянии плодородия почв. При этом, возникает настоятельная потребность в наиболее целесообразном применении минеральных удобрений, подборе их видов, форм и соотношений для увеличения урожайности и основных показателей качества сельскохозяйственных культур. Минеральные удобрения следует подбирать с учетом роста засухи зоны, с тем, чтобы независимо от уровня увлажнения, они поглощались почвой, равномерно распределялись в ней и эффективно использовались растениями. Вместе с тем, внесенные удобрения должны хорошо сказываться на основных показателях плодородия почвы и поддерживать в ней положительный баланс не только основных элементов питания, а и гумуса. В статье обосновано, что именно жидкие минеральные удобрения как простые, так и сложные, имеют определенные преимущества в эффективности по сравнению с более распространенными в применении видами твердых (сыпучих и гранулированных) удобрений.
- Published
- 2020
9. Corrosion-protective properties of 1-phenacylmethyl-2-arylcarbamido(arylthiocarbamido)pyridinium bromides
- Author
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Yurchenko, R. I., Pogrebova, I. S., Pilipenko, T. N., and Shubina, T. E.
- Published
- 2006
- Full Text
- View/download PDF
10. Anticorrosive properties of N-acetylmethylpyridinium bromides
- Author
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Yurchenko, R. I., Pogrebova, I. S., Pilipenko, T. N., and Shubina, T. E.
- Published
- 2006
- Full Text
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11. N-Phenacylpyridinium Bromides as Acid Corrosion Inhibitors
- Author
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Yurchenko, R. I., Pogrebova, I. S., Pilipenko, T. N., and Shubina, T. E.
- Published
- 2004
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- View/download PDF
12. Corrosion-Protective Properties of N-Phenacylmethylpyridinium Bromides
- Author
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Yurchenko, R. I., Pogrebova, I. S., Pilipenko, T. N., and Kras'ko, E. M.
- Published
- 2003
- Full Text
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13. Electrophysical methods for controlling the quality of vegetable oil in a digital economy
- Author
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Pilipenko, T V, primary, Nilova, L P, additional, Malyutenkova, S M, additional, and Tverskoi, V R, additional
- Published
- 2020
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- View/download PDF
14. Previous reproductive history and post-natal family planning among HIV-infected women in Ukraine†
- Author
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Saxton, J., Malyuta, R., Semenenko, I., Pilipenko, T., Tereshenko, R., Kulakovskaya, E., Adejnova, I., Kvasha, L., and Thorne, C.
- Published
- 2010
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15. 1-Phenacylmethyl-2-(acylaminothiocarbonylamino)pyridinium bromides as protectors of steel acid corrosion
- Author
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Yurchenko, R. I., Pogrebova, I. S., and Pilipenko, T. N.
- Published
- 2007
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16. Epoxy binders for manufacture of composite consumer goods
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Pet'ko, I. P., Durmanenko, N. A., Pilipenko, T. I., Episheva, O. V., Kuzovleva, L. V., Tonkha, Z. B., Fomicheva, N. P., Pandazi, I. F., Goncharov, V. V., Allaberdiev, Kh., Leonova, G. I., and Liskova, E. M.
- Published
- 1996
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17. Pyridinium Halides and Their Mixtures as Inhibitors of Steel Corrosion in Sulfuric Acid Solutions
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Yurchenko, R. I., Ivashchenko, S. V., Pilipenko, T. N., and Pogrebova, I. S.
- Published
- 2005
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18. Regulation of the pumping current as a method for controlling the temperature of the active region of a pulsed semiconductor laser
- Author
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Semenyuk, V. A. and Pilipenko, T. V.
- Published
- 1991
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19. New educational technologies as a means of cross - regional cooperation in the field of food raw material and product safety control.
- Author
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Smyatskaya, J., Bazarnova, J G, Zhilinskaya, N T, Pilipenko, T V, Belokurova, E S, Ivanchenko, O B, and Loboda, V V
- Published
- 2020
- Full Text
- View/download PDF
20. Thermodynamic Analysis of Removing the Non-Metallic Inclusions from the Molten Steel During Continuous Casting Process
- Author
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Yefimova, V. G. and Pilipenko, T. M.
- Subjects
неметалеві включення ,промежуточный ковш ,629.746.047 ,коагуляция ,tundish ,сталь ,non-metallic inclusions ,steel ,коагуляція ,coagulation ,проміжний ківш ,неметаллические включения - Abstract
Проблематика. Нині основними тенденціями розвитку металургійного виробництва в нашій країні є боротьба за підвищення якості металу в умовах загострення конкуренції як на внутрішньому, так і на світовому ринку. Одною з головних вимог, що ставляться до якісної сталі, є низький вміст неметалевих включень у готовій продукції, а також рівномірний їх розподіл по перетину металевої заготівки. З деякого часу отримання якісного металу стало можливим за рахунок рафінування його в рідкому стані на останньому етапі розливання у проміжному ковші. При цьому проведення досліджень у розливальному пристрої у промислових умовах обмежене внаслідок фізичних умов проведення процесу, а саме завеликого розміру розливального пристрою та високої температури. Ці обмеження можна подолати завдяки переміщенню експериментів з реального пристрою на фізичні моделі та подальшому дослідження якості отриманого металу металографічними методами. Видалення неметалевих включень на останньому етапі розливання є актуальною задачею. Однак проведені раніше дослідження не враховують впливу термодинамічних факторів на гідродинаміку проміжного ковша. Мета дослідження. Підвищення якості безперервнолитих заготівок. Методика реалізації. Термодинамічний аналіз процесів коагуляції та видалення неметалевих включень у шлак. Дослідження гідродинамічних процесів, які відбуваються у проміжному ковші у процесі безперервного розливання сталі і які сприяють видаленню неметалевих включень. Металографічні методики дослідження готового металу. Результати дослідження. Проведений термодинамічний аналіз дисперсної системи розплав сталі–неметалеві включення показав, що на частинках неметалевої фази утворюються металеві плівки. Фізичне моделювання гідродинамічних потоків показало, що найбільш ефективною структурою потоків, яка сприяє коагуляції неметалевих включень, є вихороподібна. Промислові випробування показали, що зразки металу, які були отримані при застосуванні реакційної камери, містять на 40–80 % менше неметалевих включень. Висновки. Для створення найбільш сприятливих умов для коагуляції неметалевої фази у проміжному ковші необхідно, щоб він був обладнаний реакційною камерою. Дані термодинамічного аналізу та фізичного моделювання узгоджуються з даними промислових випробувань. Background. Nowadays the main directions of the metallurgical production development in our country are the improvements of the metal quality, caused by the increased competition on both the internal and the world markets. One of the main requirements for the high quality steel is low content of the non-metallic inclusions in the finished product, as well as their uniform distribution along the metal blank cross-section. The manufacturing of the high quality metal has become possible, for some time now, because of its refining in the molten state at the last stage of casting in the tundish. Investigations in the casting device under the industrial conditions are limited, because of the physical conditions of the process being carried out, the too large size of the casting device and high temperature in particular. These limitations can be overcome, if the experiments are carried out not on the conventional device, but on the physical model with the further investigation of the metal quality, taking advantage of the metallographic methods. Objective. The aim of the paper is the quality improving of continuously cast steel. Methods. Thermodynamic analysis of coagulation and removal of non-metallic inclusions into slag have been applied. Investigation of hydrodynamic processes occurring in the tundish during continuous casting, which contributes to the removal of nonmetallic inclusions. Metallographic methods of investigation of finished product (steel). Results. The thermodynamic analysis of the disperse system of molten steel–non-metallic inclusions has shown that metallic films (layers) are formed on top of non-metallic phase particles. Physical modeling of hydrodynamic flows showed that the most effective structure of flows, which promotes the coagulation of nonmetallic inclusions, is a vortex type system. Industrial tests have shown that metal samples that were obtained with the use of “reaction chamber” contain 40–80 % less of non-metallic inclusions. Conclusions. In order to create the most favorable conditions for the coagulation of the non-metallic phase in the tundish, it is necessary that “reaction chamber” is used during the process. The data of thermodynamic analysis and physical modeling correspond to data of industrial tests. Проблематика. В настоящее время основными тенденциями развития металлургического производства в нашей стране является борьба за повышение качества металла в условиях обострившейся конкуренции как на внутреннем, так и на мировом рынке. Одним из главных требований, предъявляемых к качественной стали, является низкое содержание неметаллических включений в готовой продукции, а также равномерное их распределение по сечению металлической заготовки. С некоторого времени получение качественного металла стало возможным за счет рафинирования его в жидком состоянии на последнем этапе разливки в промежуточном ковше. При этом проведение исследований в разливочных устройствах в промышленных условиях ограничено вследствие физических условий проведения процесса, а именно слишком большого размера разливочного устройства и высокой температуры. Эти ограничения можно преодолеть путем перемещения экспериментов с реального устройства на физические модели и дальнейшего исследования качества полученного металла металлографическими методами. Удаление неметаллических включений на последнем этапе разливки является актуальной задачей. Однако проведенные ранее исследования не учитывают влияния термодинамических факторов на гидродинамику промежуточного ковша. Цель исследования. Повышение качества непрерывнолитых заготовок. Методика реализации. Термодинамический анализ процессов коагуляции и удаления неметаллических включений в шлак. Исследование гидродинамических процессов, протекающих в промежуточном ковше в процессе непрерывной разливки и способствующих удалению неметаллических включений. Металлографические методики исследования готового металла. Результаты исследования. Проведенный термодинамический анализ дисперсной системы расплав стали–неметаллические включения показал, что на частицах неметаллических включений образуются металлические пленки. Физическое моделирование гидродинамических потоков показало, что наиболее эффективной структурой потоков, которая способствует коагуляции неметаллических включений, является вихреобразная. Промышленные испытания показали, что образцы металла, которые были получены при применении реакционной камеры, содержат на 40–80 % меньше неметаллических включений. Выводы. Для создания наиболее благоприятных условий для коагуляции неметаллической фазы в промежуточном ковше необходимо, чтобы он был оборудован реакционной камерой. Данные термодинамического анализа и физического моделирования согласуются с данными промышленных испытаний.
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- 2018
21. Solving the problem of using dairy waste in Russia
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Pilipenko, T, primary, Belokurova, E, additional, Pankina, I, additional, and Shlykova, A, additional
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- 2019
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22. Innovative methods of human capital formation during bachelors academic training
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Belokurova, E., primary, Pankina, I., primary, and Pilipenko, T., primary
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- 2019
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23. Investigation of the growth of cavities for graphite inclusions during the annealing of white cast iron
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Neizhko, I. G. and Pilipenko, T. K.
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- 1991
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24. Protective effect of 1-benzyl-2-R-pyridinium halides in steel acid corrosion
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Yurchenko, R. I., Pilipenko, T. N., Yurchenko, M. A., and Krivovyaz, T. I.
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- 2006
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25. Physical-chemical regularities of steel refining from non-metallic inclusions
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Yefimova, V., primary and Pilipenko, T., additional
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- 2018
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26. Application of the “double pulse” method for the suppression of thermal waves in a semiconductor injection laser
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Semenyuk, V. A. and Pilipenko, T. V.
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- 1989
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27. A diglyceride uronoside from streptomyces LA 7017
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Batrakov, S. G., Pilipenko, T. V., and Bergel'son, L. D.
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- 1970
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28. A new ornithine-containing lipid from Actinomyces no. 660-15
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Batrakov, S. G., Pilipenko, T. V., and Bergel'son, L. D.
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- 1972
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29. Insufficient antiretroviral therapy in pregnancy: missed opportunities for prevention of mother-to-child transmission of HIV in Europe
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Bayley, H, Townsend, C, Cortina Borja, M, Thorne, C, Newell, Ml, Giaquinto, Carlo, Rampon, O, Mazza, A, DE ROSSI, Anita, Grosch Wörner, I, Mok, J, de José MI, Larrú Martínez, B, Ma Peña, J, Gonzalez Garcia, J, Arribas Lopez JR, Garcia Rodriguez MC, Asensi Botet, F, Otero, Mc, Pérez Tamarit, D, Scherpbier, Hj, Kreyenbroek, M, Godfried, Mh, Nellen, Fj, Boer, K, Navér, L, Bohlin, Ab, Belfrage, E, Lindgren, S, Levy, J, Barlow, P, Manigart, Y, Hainaut, M, Goetghebuer, T, Brichard, B, De Camps, J, Thiry, N, Deboone, G, Waterloos, H, Viscoli, C, De Maria, A, Bentivoglio, G, Ferrero, S, Gotta, C, Mûr, A, Pàya, A, López Vilchez MA, Carreras, R, Valerius, Nh, Rosenfeldt, V, Coll, O, Suy, A, Perez, Jm, Fortuny, C, Boguña, J, Savasi, V, Fiore, S, Crivelli, M, Viganò, A, Giacomet, V, Cerini, C, Raimondi, C, Zuccotti, G, Alberico, S, Tropea, M, Businelli, C, Taylor, Gp, Lyall, Eg, Penn, Z, Buffolano, W, Tiseo, R, Martinelli, P, Sansone, M, Maruotti, G, Agangi, A, Tibaldi, C, Marini, S, Masuelli, G, Benedetto, C, Niemieç, T, Marczynska, M, Dobosz, S, Popielska, J, Oldakowska, A, Malyuta, R, Semenenko, I, Pilipenko, T., European Collaborative Study in, Eurocoord, Buffolano, Wilma, Bailey, H, Townsend, C, Cortina Borja, M, Thorne, C., European Collaborative, Study, Martinelli, Pasquale, AII - Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology, General Internal Medicine, Infectious diseases, Other Research, and Obstetrics and Gynaecology
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Adult ,medicine.medical_specialty ,Acquired Immunodeficiency Syndrome ,HIV ,Pregnancy ,Antiviral Agents ,antiretroviral therapy ,Human immunodeficiency virus (HIV) ,HIV-1 infected women, mother-to-child transmission ,risk factors ,HIV Infections ,medicine.disease_cause ,Medical care ,Article ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Antiretroviral Therapy, Highly Active ,medicine ,Humans ,Pharmacology (medical) ,030212 general & internal medicine ,Disengagement theory ,Pregnancy Complications, Infectious ,Pharmacology ,030219 obstetrics & reproductive medicine ,business.industry ,mother-to-child transmission ,Prevention of mother to child transmission ,medicine.disease ,Antiretroviral therapy ,Infectious Disease Transmission, Vertical ,3. Good health ,Europe ,Infectious Diseases ,Family medicine ,Immunology ,HIV-1 ,Female ,business ,HIV-1 infected women ,Viral load - Abstract
Background Although mother-to-child transmission (MTCT) rates are at an all-time low in Western Europe, potentially preventable transmissions continue to occur. Duration of antenatal combination antiretroviral therapy (ART) is strongly associated with MTCT risk. Methods Data on pregnant HIV-infected women enrolled in the Western and Central European sites of the European Collaborative Study between January 2000 and July 2009 were analysed. The proportion of women receiving no antenatal ART or 1–13 days of treatment was investigated, and associated factors explored using logistic regression models. Results Of 2,148 women, 142 (7%) received no antenatal ART, decreasing from 8% in 2000–2003 to 5% in 2004– 2009 (χ2=8.73; PConclusions Over the last 10 years, around one in 11 women in this study received insufficient antenatal ART, accounting for 40% of MTCTs. One-half of these women were diagnosed before conception, suggesting disengagement from care.
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- 2011
30. Mode of delivery in HIV-infected pregnant women and prevention of mother-to-child transmission: changing practices in Western Europe
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Boer, K, England, K, Godfried, Mh, Thorne, C, Newell, Ml, Mahdavi, S, Giaquinto, Carlo, Rampon, O, Mazza, A, DE ROSSI, Anita, Worner, Ig, Mok, J, DE JOSE MI, Martinez, Bl, Pena, Jm, Garcia, Jg, Lopez, Jra, Rodriguez, Mcg, ASENSI BOTET, F, Otero, Mc, PEREZ TAMARIT, D, Scherpbier, Hj, Kreyenbroek, M, Nellen, Fjb, Naver, L, Bohlin, Ab, Lindgren, S, Kaldma, A, Belfrage, E, Levy, J, Barlow, P, Manigart, Y, Hainaut, M, Goetghebuer, T, Brichard, B, DE BRUYCKER JJ, Thiry, N, Waterloos, H, Viscoli, C, DE MARIA, A, Bentivoglio, G, Ferrero, S, Gotta, C, Mur, A, Paya, A, LOPEZ VILCHEZ MA, Carreras, R, Valerius, Nh, Rosenfeldt, V, Coll, O, Suy, A, Perez, Jm, Fortuny, C, Boguna, J, Savasi, V, Fiore, S, Crivelli, M, Vigano, A, Giacomet, V, Cerini, C, Raimondi, C, Zuccotti, G, Alberico, S, Tropea, M, Businelli, C, Taylor, Gp, Lyall, Egh, Penn, Z, Buffolano, W, Tiseo, R, Martinelli, P, Sansone, M, Maruotti, G, Agangi, A, Tibaldi, C, Marini, S, Masuelli, G, Benedetto, C, Niemiec, T, Marczynska, M, Dobosz, S, Popielska, J, Oldakowska, A, Malyuta, R, Semenenko, I, Pilipenko, T., Other Research, Obstetrics and Gynaecology, AII - Amsterdam institute for Infection and Immunity, General Internal Medicine, and Martinelli, Pasquale
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mode of delivery ,HIV Infections ,0302 clinical medicine ,prevention ,Pregnancy ,Antiretroviral Therapy, Highly Active ,Pharmacology (medical) ,030212 general & internal medicine ,Young adult ,Pregnancy Complications, Infectious ,Substance Abuse, Intravenous ,elective caesarean section, mode of delivery, mother-to-child transmission, prevention ,030219 obstetrics & reproductive medicine ,pregnancy mother-to-child transmission ,Vaginal delivery ,Obstetrics ,Health Policy ,Prenatal Care ,Viral Load ,3. Good health ,Substance abuse ,Europe ,Infectious Diseases ,Premature birth ,Premature Birth ,Reverse Transcriptase Inhibitors ,Female ,medicine.symptom ,delivery ,Viral load ,Zidovudine ,Adult ,medicine.medical_specialty ,elective caesarean section ,Prenatal care ,Article ,03 medical and health sciences ,Young Adult ,medicine ,Humans ,business.industry ,Cesarean Section ,mother-to-child transmission ,HIV ,Infant, Newborn ,Infant ,medicine.disease ,Delivery, Obstetric ,Infectious Disease Transmission, Vertical ,Low birth weight ,business ,Epidemiologic Methods - Abstract
Objectives The aim of the study was to examine temporal and geographical patterns of mode of delivery in the European Collaborative Study (ECS), identify factors associated with elective caesarean section (CS) delivery in the highly active antiretroviral therapy (HAART) era and explore associations between mode of delivery and mother-to-child transmission (MTCT). Methods The ECS is a cohort study in which HIV-infected pregnant women are enrolled and their infants prospectively followed. Data on 5238 mother-child pairs (MCPs) enrolled in Western European ECS sites between 1985 and 2007 were analysed. Results The elective CS rate increased from 16% in 1985-1993 to 67% in 1999-2001, declining to 51% by 2005-2007. In 2002-2004, 10% of infants were delivered vaginally, increasing to 34% by 2005-2007. During the HAART era, women in Belgium, the United Kingdom and the Netherlands were less likely to deliver by elective CS than those in Italy and Spain [adjusted odds ratio (AOR) 0.07; 95% confidence interval (CI) 0.04-0.12]. The MTCT rate in 2005-2007 was 1%. Among MCPs with maternal HIV RNA
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- 2010
31. An investigation into the effects of bioactive substances from vegetable oils on the antioxidant properties of bakery products.
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Nilova, L., Pilipenko, T., and Malyutenkova, S.
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ANTIOXIDANTS , *BAKED products , *VEGETABLE oils , *DOUGH , *PUMPKINSEED oil - Abstract
This article discusses ways in which the antioxidant capacity of bakery products (otherwise referred to as 'BPs') can be increased by adding various types of vegetable oil to the dough: chosen as test oil was unrefined rice bran oil, unrefined pumpkin seed oil, and refined and deodorised sunflower oil. The authors conducted a study of fatty acid compositions and biologically active substances to be found in vegetable oils. The antioxidant properties of vegetable oils were analysed according to the following characteristics: the formation of the primary (peroxide value) and secondary (anisidine value) oxidation products; the oxidation coefficient (IR spectroscopy) which can be determined in the process of applying thermal treatment (with five hours of heating at 120 °C), which leads to the Vitamin E being destroyed. The biochemical composition of vegetable oils affected their resistance to the thermal oxidation process in the following sequence: unrefined rice bran oil > unrefined pumpkin seed oil > refined and deodorised sunflower oil. BPs were made from wheat flour dough with the addition of 4% of the corresponding vegetable oil and 5% of sugar, and were baked at two temperature regimes: at 200 °C and at 220 °C. The antioxidant activity of the BPs was determined by means of two methods: by chemiluminescence, and by DPPH radical assay. The antioxidant activity of the BPs varies depending on the vegetable oil being used, with the differences being revealed in the following way: BPs with unrefined pumpkin seed oil > BPs with unrefined rice bran oil > BPs with refined and deodorised sunflower oil. Any increase in the baking temperature reduced the antioxidant activity of the BPs; the antioxidant properties in the crust and the crumb were reduced at differing rates. [ABSTRACT FROM AUTHOR]
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- 2017
32. Synthetic studies in the field of chlorobium chlorophyll: III. Synthesis of unsymmetrical dipyrrolylmethanemonocarboxylic acids
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Filippovich, E. I., Pilipenko, T. N., Demidkina, T. V., and Preobrazhenskii, N. A.
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- 1970
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33. Levels and patterns of HIV RNA viral load in untreated pregnant women
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Patel, D, Thorne, C, Newell, Ml, CORTINA BORJA, M, Giaquinto, Carlo, Rampon, O, D'Elia, R, DE ROSSI, Anita, GROSCH WORNER, I, Mok, J, DE JOSE MI, Martinez, Bl, Pena, Jm, Garcia, Jg, Lopez, Jra, GARCIA RODRIGUEZ, J, ASENSI BOTET, F, Otero, Mc, PEREZ TAMARIT, D, Scherpbier, Hj, Kreyenbroek, M, Godfried, Mh, Nellen, Fjb, Boer, K, Ehrnst, A, Bohlin, Ab, Lindgren, S, Anzen, B, Lidman, K, Levy, J, Barlow, P, Manigart, Y, Hainaut, M, Goetghebuer, T, Ferrazin, A, Viscoli, C, DE MARIA, A, Bentivoglio, G, Ferrero, S, Gotta, C, Mur, A, Paya, A, LOPEZ VILCHEZ MA, Carreras, R, Valerius, Nh, Rosenfeldt, V, Jimenez, J, Coll, O, Suy, A, Perez, Jm, Fortuny, C, Boguna, J, Caro, Mc, Canet, Y, Ravizza, M, Guerra, B, Lanari, M, Bianchi, S, Bovicelli, L, Prati, E, Duse, M, Scaravelli, G, Stegagno, M, DE SANTIS, M, Savasi, V, Fiore, S, Crivelli, M, Ferrazzi, E, Vigano, A, Giacomet, V, Cerini, C, Raimondi, C, Zuccotti, G, Probizer, Fr, Maccabruni, A, Bucceri, A, Rancilio, L, Alberico, S, Rabusin, M, Bernardon, M, Taylor, Gp, Lyall, Egh, Penn, Z, Buffolano, W, Tiseo, R, Martinelli, A, Sansone, M, Maruotti, G, Agangi, A, Tibaldi, C, Marini, S, Masuelli, G, Benedetto, C, Niemiec, T, Marczynska, M, Dobosz, S, Popielska, J, Oldakowska, A, Malyuta, R, Semenenko, I, Pilipenko, T, Posokhova, S, Kaleeva, T, Stelmah, A, Kiseleva, G., European Collaborative Study, Patel D, Thorne C, Newell ML, Cortina-Borja M [, Guerra B, Lanari M ], Amsterdam institute for Infection and Immunity, Paediatric Infectious Diseases / Rheumatology / Immunology, General Internal Medicine, Infectious diseases, Other Research, and Obstetrics and Gynaecology
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Microbiology (medical) ,Adult ,medicine.medical_specialty ,Race ,Adolescent ,Black People ,Gestational Age ,HIV Infections ,Disease ,White People ,HIV ,Pregnancy ,HIV RNA viral load ,ART-naïve ,Young Adult ,Asian People ,pregnancy ,Medicine ,Humans ,Young adult ,Pregnancy Complications, Infectious ,business.industry ,Obstetrics ,Confounding ,RNA ,Gestational age ,General Medicine ,Viral Load ,medicine.disease ,CD4 Lymphocyte Count ,hiv ,art-naïve ,hiv rna viral load ,race ,art-naive ,Infectious Diseases ,Immunology ,HIV-1 ,RNA, Viral ,Female ,Sample collection ,business ,Viral load - Abstract
Objective: To assess pregnancy levels and patterns of HIV RNA in the absence of antiretroviral therapy, while appropriately adjusting for potential confounders, including maternal immune status and race. Methods: Data on >= 1 antenatal HIV RNA measurements were available for 333 untreated HIV-infected pregnant women enrolled in the European Collaborative Study. CD4 counts and HIV RNA measurements were routinely collected from 1992 and 1998, respectively. Linear mixed effects models based on 246 women for whom complete data were available examined changes in HIV RNA levels over pregnancy, with a nested random effects term accounting for measurement variability within women and period of sample collection. Results: The change in HIV RNA over pregnancy varied significantly by race (p = 0.005): from the second trimester until delivery, HIV RNA decreased significantly by an estimated 0.019 log(10) copies/ml/week in white women (95% Cl -0.03, -0.007); in black women the estimated 0.016 log(10) copies/ml/week increase (95% Cl -0.005, 0.037) was not statistically significant. At delivery, HIV RNA levels in black women were 0.45 log(10) copies/ml higher (95% Cl 0.08, 0.83) than in white women. Conclusions: Our findings suggest that HIV RNA dynamics over pregnancy differ by race, although other interpretations cannot be excluded, due to potential for unmeasured confounding. (C) 2008 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved
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34. An investigation into the effects of bioactive substances from vegetable oils on the antioxidant properties of bakery products
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Nilova, L., Pilipenko, T., and Svetlana Malyutenkova
35. Identification of Natural Curcumins
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Berzin, V. B., Katsitadze, L. G., Pilipenko, T. V., Vladimir Ovcharenko, and Miroshnikov, A. I.
36. ChemInform Abstract: SYNTHETISCHE UNTERSUCHUNGEN IM BEREICH DES CHLOROBIUM‐CHLOROPHYLLS 3. MITT. DIE SYNTHESE DER MONOCARBONSAEUREN VON ASYMMETRISCHEN DIPYRROLYLMETHANEN
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FILIPPOVIC, E. I., primary, PILIPENKO, T. N., additional, DEMIDKINA, T. V., additional, and PREOBRAZENSKIJ, N. A., additional
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- 1971
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37. Exploring ultrasonic communication in mice treated with Cannabis sativa oil: Audio data processing and correlation study with different behaviours.
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Pilipenko T, Premoli M, Gnutti A, Bonini SA, Leonardi R, Memo M, and Migliorati P
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- Animals, Mice, Male, Cannabis, Ultrasonics, Social Behavior, Behavior, Animal drug effects, Behavior, Animal physiology, Vocalization, Animal drug effects, Vocalization, Animal physiology, Plant Oils pharmacology
- Abstract
Studying ultrasonic vocalizations (USVs) plays a crucial role in understanding animal communication, particularly in the field of ethology and neuropharmacology. Communication is associated with social behaviour; so, USVs study is a valid assay in behavioural readout and monitoring in this context. This paper delved into an investigation of ultrasonic communication in mice treated with Cannabis sativa oil (CS mice), which has been demonstrated having a prosocial effect on behaviour of mice, versus control mice (vehicle-treated, VH mice). To conduct this study, we created a dataset by recording audio-video files and annotating the duration of time that test mice spent engaging in social activities, along with categorizing the types of emitted USVs. The analysis encompassed the frequency of individual sounds as well as more complex sequences of consecutive syllables (patterns). The primary goal was to examine the extent and nature of diversity in ultrasonic communication patterns emitted by these two groups of mice. As a result, we observed statistically significant differences for each considered pattern length between the two groups of mice. Additionally, the study extended its research by considering specific behaviours, aiming to ascertain whether dissimilarities in ultrasonic communication between CS and VH mice are more pronounced or subtle within distinct behavioural contexts. Our findings suggest that while there is variation in USV communication between the two groups of mice, the degree of this diversity may vary depending on the specific behaviour being observed., (© 2024 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.)
- Published
- 2024
- Full Text
- View/download PDF
38. [Evaluation of antioxidant properties of enriched bakery products in experiment on laboratory animals].
- Author
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Nilova LP and Pilipenko TV
- Subjects
- Animals, Male, Rats, Rats, Wistar, Antioxidants metabolism, Bread, Food, Fortified, Free Radicals blood
- Abstract
The purpose was to study the effect of enriched bakery products in the diet of rats on indicators of prooxidant-antioxidant system of blood serum. Experiment was carried out on male Wistar rats with initial weight 140-180 g. After a quarantine during the preparatory period rats for 14 days were accustomed to the partial (50%) replacement of the standard diet by bakery products with standard compounding. Then, 7 groups of rats were formed: the 1st group of rats (control group, n=10) continued to receive bakery products of a standard composition; groups with the 2nd on 7th (experimental, n=8 in everyone) received enriched bakery products: the 2nd group - with blueberry powder; the 3rd group - with mountain ash powder; the 4th group - with sea-buckthorn powder; the 5th group - with flour of a pine nut; the 6th group - with rice bran oil; the 7th group - with pumpkin oil. The intensity of free radical oxidation and antioxidant activity (by chemiluminescence method), activity of superoxide dismutase and level of secondary oxidation products reacted with thiobarbituric acid (by spectrophotometry) were monitored in rat blood serum. It has been shown that the use of bakery products with different compounding in the animal diet had different effects on indicators of prooxidant-antioxidant system of blood serum. Bakery products containing sea buckthorn pomace powder, flour of pine nut and rice bran oil reduced intensity of free radical oxidation in rat blood serum by 36.0, 24.6 and 18.8%, respectively. It is suggested that bakery products containing flour of pine nut products brake a free radical oxidation in rat blood serum in case of simultaneous content of natural antioxidants and melanoidins. The anthocyanins of powder from blueberry berries can render antioxidant effect and slow down formation of by-products of oxidation. No statistically significant change on indicators of prooxidant-antioxidant system of blood serum of rats treated with bakery products with rowan powder or pumpkin oil was found, that may be due to animal refusal to eat such products.
- Published
- 2016
39. Factors associated with abandonment of infants born to HIV-positive women: results from a Ukrainian birth cohort.
- Author
-
Bailey H, Semenenko I, Pilipenko T, Malyuta R, and Thorne C
- Subjects
- Adult, Child Welfare statistics & numerical data, Child, Preschool, Female, HIV Infections drug therapy, HIV Infections epidemiology, HIV Infections transmission, Humans, Infant, Male, Parent-Child Relations, Pregnancy, Prenatal Care, Regression Analysis, Risk Factors, Socioeconomic Factors, Ukraine epidemiology, Anti-HIV Agents therapeutic use, Child, Abandoned statistics & numerical data, HIV Infections psychology, Infectious Disease Transmission, Vertical statistics & numerical data, Pregnancy Complications, Infectious drug therapy, Pregnancy Complications, Infectious virology
- Abstract
Social marginalisation and other challenges facing HIV-positive pregnant women in Ukraine may put them at increased risk of relinquishing their infants to the state. We described rates of infant abandonment (exclusive non-parental care to most recent follow-up, censored at two years of age) and investigated associated factors using logistic regression models, in 4759 mother-infant pairs enrolled across six Ukrainian sites in the European Collaborative Study from 2000 to May 2009. Median maternal age was 26.0 years, 81.8% were married or cohabiting and 60.6% were nulliparous at enrolment. An injecting drug use (IDU) history was reported by 18.4%, 80.2% took antiretroviral therapy (ART) antenatally and most deliveries were vaginal. A small but significant proportion of infants had been cared for exclusively in institutions by their second birthday (2.1% overall), decreasing from 3.8% (15/393) in 2000-2002 to 1.6% (49/3136) in 2006-2009 (p<0.01), concurrent with prevention of mother-to-child transmission scale-up. A further 1% of infants spent some time in non-parental care. Antenatal ART was associated with an 88% reduced abandonment risk (adjusted odds ratio (AOR) 0.12), versus receipt of single dose nevirapine only, and this was reflected in HIV infection prevalence in the two groups (17.1% of abandoned infants versus 6.6% in parental care). Mothers without a cohabiting partner or husband were more likely to abandon (AOR 4.08), as were active IDUs (AOR 3.27) and those with ≥1 previous children (AOR 1.89 for second-born and AOR 2.56 for subsequent births). Women delivering by elective caesarean section were less likely to abandon (AOR 0.37 versus vaginal), as were those leaving full-time education later (AOR 0.61 for 17-18 years versus ≤16 years and AOR 0.23 for ≥19 years versus ≤16 years). Interventions to extend family planning and IDU harm reduction services along with non-stigmatising antenatal care to marginalised women are needed, and may reduce abandonment.
- Published
- 2010
- Full Text
- View/download PDF
40. Treatment and disease progression in a birth cohort of vertically HIV-1 infected children in Ukraine.
- Author
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Mahdavi S, Malyuta R, Semenenko I, Pilipenko T, and Thorne C
- Subjects
- Female, Follow-Up Studies, HIV Infections epidemiology, HIV Infections transmission, Humans, Incidence, Infant, Newborn, Pregnancy, Prevalence, Prognosis, Prospective Studies, Survival Rate, Ukraine epidemiology, Anti-Retroviral Agents therapeutic use, Disease Progression, HIV Infections drug therapy, HIV-1 genetics, Infectious Disease Transmission, Vertical, Pregnancy Complications, Infectious, RNA, Viral analysis
- Abstract
Background: Ukraine has the highest HIV prevalence (1.6%) and is facing the fastest growing epidemic in Europe. Our objective was to describe the clinical, immunological and virological characteristics, treatment and response in vertically HIV-infected children living in Ukraine and followed from birth., Methods: The European Collaborative Study (ECS) is an ongoing cohort study, in which HIV-1 infected pregnant women are enrolled and followed in pregnancy, and their children prospectively followed from birth. ECS enrolment in Ukraine started in 2000 initially with three sites, increasing to seven sites by 2009., Results: A total of 245 infected children were included in the cohort by April 2009, with a median age of 23 months at most recent follow-up; 33% (n = 77) had injecting drug using mothers and 85% (n = 209) were infected despite some use of antiretroviral prophylaxis for prevention of mother-to-child transmission. Fifty-five (22%) children had developed AIDS, at a median age of 10 months (IQR = 6-19). The most prevalent AIDS indicator disease was Pneumocystis jiroveci pneumonia (PCP). Twenty-seven (11%) children had died (median age, 6.2 months). Overall, 108 (44%) children had started highly active antiretroviral treatment (HAART), at a median 18 months of age; median HAART duration was 6.6 months to date. No child discontinued HAART and 92% (100/108) remained on their first-line HAART regimen to date. Among children with moderate/severe immunosuppression, 36% had not yet started HAART. Among children on HAART, 71% (69/97) had no evidence of immunosuppression at their most recent visit; the median reduction in HIV RNA was 4.69 log10 copies/mL over a median of 10 months treatment. From survival analysis, an estimated 94%, 84% and 81% of children will be alive and AIDS-free at 6, 12 and 18 months of age, respectively. However, survival increased significantly over time: estimated survival rates to 12 months of age were 87% for children born in 2000/03 versus 96% for those born in 2004/08., Conclusion: One in five children had AIDS and one in ten had died. The half of children who received HAART has responded well and survival has significantly improved over time. Earlier diagnosis and prompt initiation of HAART remain key challenges.
- Published
- 2010
- Full Text
- View/download PDF
41. [Characteristic of gut microorganisms abnormalities].
- Author
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Batchaev KhKh, Arapova VI, and Pilipenko TD
- Subjects
- Adolescent, Child, Child, Preschool, Colony Count, Microbial, Enterohemorrhagic Escherichia coli isolation & purification, Feces microbiology, Humans, Infant, Infant, Newborn, Risk Factors, Russia epidemiology, Staphylococcus aureus isolation & purification, Intestinal Diseases epidemiology, Intestinal Diseases microbiology, Intestine, Large microbiology
- Abstract
Aim: To study dynamics of qualitative and quantitative changes of microflora of large intestine in different age groups., Materials and Methods: Stool samples from children of different age groups (0 - 6 months, 6 months - 1 year, 1 - 7 years, 7 - 14 years, >14 years) were tested on dysbiosis., Results: Majority of patients admitted during the period of 1999 - 2008 were children 1 - 7 years old (32 - 38%). The highest rate of dysbiosis was observed in infants (92 - 100%). Leading place in pathology of microbiota of large intestine during all study period belonged to Staphylococcus aureus and hemolytic Escherichia coli., Conclusion: In Karachaevo-Cherkessk republic tightening of measures for surveillance on infection control regime in health-care organizations as well as on carriage of S. aureus in health-care workers are needed.
- Published
- 2010
42. Progress in prevention of mother-to-child transmission of HIV infection in Ukraine: results from a birth cohort study.
- Author
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Thorne C, Semenenko I, Pilipenko T, and Malyuta R
- Subjects
- Adult, Anti-HIV Agents therapeutic use, Cohort Studies, Female, HIV Infections drug therapy, HIV Infections prevention & control, HIV-1, Humans, Infant, Pregnancy, Substance Abuse, Intravenous epidemiology, Ukraine epidemiology, Zidovudine therapeutic use, HIV Infections transmission, Infectious Disease Transmission, Vertical prevention & control, Pregnancy Complications, Infectious drug therapy
- Abstract
Background: Ukraine was the epicentre of the HIV epidemic in Eastern Europe, which has the most rapidly accelerating HIV epidemic world-wide today; national HIV prevalence is currently estimated at 1.6%. Our objective was to evaluate the uptake and effectiveness of interventions for prevention of mother-to-child transmission (PMTCT) over an eight year period within operational settings in Ukraine, within the context of an ongoing birth cohort study., Methods: The European Collaborative Study (ECS) is an ongoing birth cohort study in which HIV-infected pregnant women identified before or during pregnancy or at delivery were enrolled and their infants prospectively followed. Three centres in Ukraine started enrolling in 2000, with a further three joining in September 2006., Results: Of the 3356 women enrolled, 21% (689) reported current or past injecting drug use (IDU). Most women were diagnosed antenatally and of those, the proportion diagnosed in the first/second trimester increased from 47% in 2000/01 (83/178) to 73% (776/1060) in 2006/07 (p < 0.001); intrapartum diagnosis was associated with IDU (Adjusted odds ratio 4.38; 95%CI 3.19-6.02). The percentage of women not receiving any antiretroviral prophylaxis declined from 18% (36/205) in 2001 to 7% in 2007 (61/843) (p < 0.001). Use of sdNVP alone substantially declined after 2003, with a concomitant increase in zidovudine prophylaxis. Median antenatal zidovudine prophylaxis duration increased from 24 to 72 days between 2000 and 2007. Elective caesarean section (CS) rates were relatively stable over time and 34% overall. Mother-to-child transmission (MTCT) rates decreased from 15.2% in 2001 (95%CI 10.2-21.4) to 7.0% in 2006 (95%CI 2.6-14.6). In adjusted analysis, MTCT risk was reduced by 43% with elective CS versus vaginal delivery and by 75% with zidovudine versus no prophylaxis., Conclusion: There have been substantial improvements in use of PMTCT interventions in Ukraine, including earlier diagnosis of HIV-infected pregnant women and increasing coverage with antiretroviral prophylaxis and the initial MTCT rate has more than halved. Future research should focus on hard-to-reach populations such as IDU and on missed opportunities for further reducing the MTCT rate.
- Published
- 2009
- Full Text
- View/download PDF
43. Mother-to-child transmission risk is increased among HIV-infected pregnant women in Ukraine with serological test results positive for syphilis.
- Author
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Thorne C, Malyuta R, Semenenko I, Pilipenko T, Stelmah A, Posokhova S, and Newell ML
- Subjects
- Adolescent, Adult, Female, HIV Infections epidemiology, Humans, Infant, Newborn, Pregnancy, Pregnancy Complications, Infectious epidemiology, Risk Assessment, Syphilis epidemiology, Syphilis Serodiagnosis, Ukraine epidemiology, HIV Infections complications, HIV Infections transmission, Infectious Disease Transmission, Vertical, Syphilis diagnosis
- Published
- 2008
- Full Text
- View/download PDF
44. [Shigellosis in Karachaevo-Cherkes Republic in 1996-2005].
- Author
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Batchaev KhKh, Arapova VI, Pilipenko TD, Bolatchiev KKh, and Arkhipova NI
- Subjects
- Anti-Bacterial Agents pharmacology, Chloramphenicol pharmacology, Dysentery, Bacillary microbiology, Health Surveys, Humans, Incidence, Russia epidemiology, Shigella sonnei drug effects, Shigella sonnei isolation & purification, Tetracycline pharmacology, Dysentery, Bacillary epidemiology
- Abstract
Incidence and etiologic structure of shigellosis in Karachaevo-Cherkes Republic for 10 years are analyzed and compared with same characteristics in Russia overall. Sharp rise of shigellosis cases number is detected in 2003-2005 as well as predominance of Shigella sonnei represented by biovar Ilg. It was shown that Shigella strains with different resistance to tetracycline and chloramphenicol circulate in Karachaevo-Cherkes Republic.
- Published
- 2007
45. [Synthesis and properties of an acyclic analog of 9-deazainosine and related compounds].
- Author
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Ektova LV, Tolkachev VN, Sizova OS, Nikolaeva TG, and Pilipenko TV
- Subjects
- Antineoplastic Agents, Antiviral Agents, Cell Division drug effects, Cells, Cultured, Chemical Phenomena, Chemistry, Female, Humans, Inosine chemical synthesis, Inosine pharmacology, Ovarian Neoplasms pathology, Simplexvirus drug effects, Structure-Activity Relationship, Inosine analogs & derivatives
- Abstract
An acyclic analogue of 9-deazainosine, 9-(2-hydroxyethoxymethyl)-9-deazahypoxanthine, and related compounds have been synthesized starting from 9-(hydroxyethyl)-9-deazahypoxanthine. The acyclo-9-deazainosine exhibited some cytotoxic activity.
- Published
- 1985
46. [Use of a substance based on iodophor for washing and disinfecting dishes in public eating establishments].
- Author
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Iosilevich AI, Suchkov VV, Sergeev VS, and Pilipenko TV
- Subjects
- Escherichia coli drug effects, USSR, Cooking and Eating Utensils, Detergents, Disinfection, Iodine, Sterilization
- Published
- 1974
47. [New ornithine-containing lipid from Actinomyces].
- Author
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Batrakov SG, Pilipenko TV, and Bergel'son LD
- Subjects
- Lipids analysis, Actinomyces metabolism, Lipids biosynthesis, Ornithine
- Published
- 1971
48. A new glycolipid from Streptomyces.
- Author
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Bergelson LD, Batrakov SG, and Pilipenko T
- Subjects
- Chromatography, Gas, Chromatography, Thin Layer, Glycerides analysis, Hydrogen-Ion Concentration, Infrared Rays, Methane, Methylation, Oxidation-Reduction, Spectrophotometry, Glycolipids analysis, Streptomyces analysis
- Published
- 1970
- Full Text
- View/download PDF
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