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Mode of delivery in HIV-infected pregnant women and prevention of mother-to-child transmission: changing practices in Western Europe
- Source :
- HIV medicine, 11(6), 368-378. Wiley-Blackwell
- Publication Year :
- 2010
- Publisher :
- WILEY-BLACKWELL, 2010.
-
Abstract
- Objectives The aim of the study was to examine temporal and geographical patterns of mode of delivery in the European Collaborative Study (ECS), identify factors associated with elective caesarean section (CS) delivery in the highly active antiretroviral therapy (HAART) era and explore associations between mode of delivery and mother-to-child transmission (MTCT). Methods The ECS is a cohort study in which HIV-infected pregnant women are enrolled and their infants prospectively followed. Data on 5238 mother-child pairs (MCPs) enrolled in Western European ECS sites between 1985 and 2007 were analysed. Results The elective CS rate increased from 16% in 1985-1993 to 67% in 1999-2001, declining to 51% by 2005-2007. In 2002-2004, 10% of infants were delivered vaginally, increasing to 34% by 2005-2007. During the HAART era, women in Belgium, the United Kingdom and the Netherlands were less likely to deliver by elective CS than those in Italy and Spain [adjusted odds ratio (AOR) 0.07; 95% confidence interval (CI) 0.04-0.12]. The MTCT rate in 2005-2007 was 1%. Among MCPs with maternal HIV RNA
- Subjects :
- mode of delivery
HIV Infections
0302 clinical medicine
prevention
Pregnancy
Antiretroviral Therapy, Highly Active
Pharmacology (medical)
030212 general & internal medicine
Young adult
Pregnancy Complications, Infectious
Substance Abuse, Intravenous
elective caesarean section, mode of delivery, mother-to-child transmission, prevention
030219 obstetrics & reproductive medicine
pregnancy mother-to-child transmission
Vaginal delivery
Obstetrics
Health Policy
Prenatal Care
Viral Load
3. Good health
Substance abuse
Europe
Infectious Diseases
Premature birth
Premature Birth
Reverse Transcriptase Inhibitors
Female
medicine.symptom
delivery
Viral load
Zidovudine
Adult
medicine.medical_specialty
elective caesarean section
Prenatal care
Article
03 medical and health sciences
Young Adult
medicine
Humans
business.industry
Cesarean Section
mother-to-child transmission
HIV
Infant, Newborn
Infant
medicine.disease
Delivery, Obstetric
Infectious Disease Transmission, Vertical
Low birth weight
business
Epidemiologic Methods
Subjects
Details
- Language :
- English
- ISSN :
- 14642662
- Database :
- OpenAIRE
- Journal :
- HIV medicine, 11(6), 368-378. Wiley-Blackwell
- Accession number :
- edsair.doi.dedup.....870f49e69e60e717eacf1ea6278af2f8