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1. Outcomes Following Transcatheter Mitral Valve Replacement Using Dedicated Devices in Patients With Mitral Annular Calcification

Author

Coisne, Augustin, Ludwig, Sebastian, Scotti, Andrea, Ben Ali, Walid, Weimann, Jessica, Duncan, Alison, Webb, John G., Kalbacher, Daniel, Rudolph, Tanja K., Nickenig, Georg, Hausleiter, Jörg, Ruge, Hendrik, Adam, Matti, Petronio, Anna S., Dumonteil, Nicolas, Søndergaard, Lars, Adamo, Marianna, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Dahle, Gry, Taramasso, Maurizio, Walther, Thomas, Kempfert, Joerg, Obadia, Jean-François, Redwood, Simon, Tang, Gilbert H.L., Goel, Sachin, Fam, Neil, Metra, Marco, Andreas, Martin, Muller, David W., Denti, Paolo, Praz, Fabien, von Bardeleben, Ralph Stephan, Leroux, Lionel, Latib, Azeem, Granada, Juan F., Conradi, Lenard, and Modine, Thomas

Published
2024
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3. Impact of Transcatheter Edge-to-Edge Mitral Valve Repair on Guideline-Directed Medical Therapy Uptitration

Author

Adamo, Marianna, Tomasoni, Daniela, Stolz, Lukas, Stocker, Thomas J., Pancaldi, Edoardo, Koell, Benedikt, Karam, Nicole, Besler, Christian, Giannini, Cristina, Sampaio, Francisco, Praz, Fabien, Ruf, Tobias, Pechmajou, Louis, Neuss, Michael, Iliadis, Christos, Baldus, Stephan, Butter, Christian, Kalbacher, Daniel, Lurz, Philipp, Melica, Bruno, Petronio, Anna S., von Bardeleben, Ralph Stephan, Windecker, Stephan, Butler, Javed, Fonarow, Gregg C., Hausleiter, Jörg, and Metra, Marco

Published
2023
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4. Pre-procedural oral anticoagulant use is associated with cardiovascular events in women after transcatheter aortic valve replacement: An analysis from the WIN-TAVI cohort

Author

van Bergeijk, Kees H., Wykrzykowska, Joanna J., Sartori, Samantha, Snyder, Clayton, Vogel, Birgit, Tchetche, Didier, Petronio, Anna S., Mehilli, Julinda, Lefèvre, Thierry, Presbitero, Patrizia, Capranzano, Piera, Iadanza, Alessandro, Sardella, Gennaro, Van Mieghem, Nicolas M., Meliga, Emanuele, Dumonteil, Nicolas, Fraccaro, Chiara, Trabattoni, Daniela, Mikhail, Ghada, Ferrer-Gracia, Maria-Cruz, Naber, Christoph, Kievit, Peter, Sharma, Samin K., Morice, Marie-Claude, Dangas, George D., Chieffo, Alaide, Voors, Adriaan A., and Mehran, Roxana

Published
2023
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5. Impact of Small Valve Size on 1-Year Outcomes After Transcatheter Aortic Valve Implantation in Women (from the WIN-TAVI Registry)

Author

Pivato, Carlo A., Cao, Davide, Spirito, Alessandro, Sartori, Samantha, Nicolas, Johny, Chiarito, Mauro, Snyder, Clayton, Mehilli, Julinda, Lefèvre, Thierry, Stefanini, Giulio G., Presbitero, Patrizia, Capranzano, Piera, Tchetche, Didier, Iadanza, Alessandro, Vogel, Birgit, Sardella, Gennaro, Van Mieghem, Nicolas M., Nardin, Matteo, Tavenier, Anne H., Meliga, Emanuele, Dumonteil, Nicholas, Fraccaro, Chiara, Trabattoni, Daniela, Mikhail, Ghada, Sharma, Samin, Ferrer, Maria Cruz, Naber, Christoph, Kievit, Peter, Baber, Usman, Petronio, Anna S., Morice, Marie C., Chieffo, Alaide, Dangas, George, and Mehran, Roxana

Published
2022
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6. Transcatheter Mitral Valve Replacement Versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score–Matched Comparison

Author

Ludwig, Sebastian, Conradi, Lenard, Cohen, David J., Coisne, Augustin, Scotti, Andrea, Abraham, William T., Ben Ali, Walid, Zhou, Zhipeng, Li, Yanru, Kar, Saibal, Duncan, Alison, Lim, D. Scott, Adamo, Marianna, Redfors, Björn, Muller, David W.M., Webb, John G., Petronio, Anna S., Ruge, Hendrik, Nickenig, Georg, Sondergaard, Lars, Adam, Matti, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Andreas, Martin, Dahle, Gry, Walther, Thomas, Kempfert, Joerg, Tang, Gilbert H.L., Redwood, Simon, Taramasso, Maurizio, Praz, Fabien, Fam, Neil, Dumonteil, Nicolas, Obadia, Jean-François, von Bardeleben, Ralph Stephan, Rudolph, Tanja K., Reardon, Michael J., Metra, Marco, Denti, Paolo, Mack, Michael J., Hausleiter, Jörg, Asch, Federico M., Latib, Azeem, Lindenfeld, JoAnn, Modine, Thomas, Stone, Gregg W., and Granada, Juan F.

Published
2023
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8. European Society of Cardiology quality indicators for the care and outcomes of adults undergoing transcatheter aortic valve implantation

Author

Ali, Noman, Aktaa, Suleman, Younsi, Tanina, Beska, Ben, Batra, Gorav, Blackman, Daniel J, James, Stefan, Ludman, Peter, Mamas, Mamas A, Abdel-Wahab, Mohamed, Borregaard, Britt, Iung, Bernard, Joner, Michael, Kunadian, Vijay, Modine, Thomas, Neylon, Antoinette, Petronio, Anna S, Pibarot, Philippe, Popescu, Bogdan A, Sabaté, Manel, Stortecky, Stefan, Teles, Rui C, Treede, Hendrik, and Gale, Chris P

Abstract

Graphical AbstractCentral illustration. The 2023 ESC quality indicators for TAVI. AKI, acute kidney injury; AS, aortic stenosis; GA, general anaesthesia; GCCT, gated cardiac computed tomography; MDT, multidisciplinary team; OAC, oral anti-coagulant; PCI, percutaneous coronary intervention; PROMs, patient-reported outcome measures; PVL, paravalvular leak; PPM, permanent pacemaker; QI, quality indicator; SAPT, single antiplatelet therapy; TAVI, transcatheter aortic valve implantation; TF, transfemoral; ViV, valve-in-valve.

Published
2024
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9. Abstract 14790: Impact of Pre-Frailty and Frailty in Women Undergoing TAVR: Insights From the WIN-TAVI Registry

Author

Petrovic, Marija, Spirito, Alessandro, Sartori, Samantha, Snyder, Clayton, Vogel, Birgit, Nicolas, Johny, Cohen, Rebecca M, Cao, Davide, Tchetche, Didier, Petronio, Anna S, Mehilli, Julinda, Lefevre, Thierry, Presbitero, Patrizia, Capranzano, Piera, IADANZA, ALESSANDRO, Sardella, Gennaro, Van Mieghem, Nicolas M, meliga, emanuele, DUMONTEIL, Nicolas, Fraccaro, Chiara, Trabattoni, Daniela, Mikhail, Ghada, Ferrer-Gracia, Maria-Cruz, Naber, Christoph, Kievit, Peter C, Sharma, Samin K, Morice, Marie C, Dangas, George, Chieffo, Alaide, and Mehran, Roxana

Published
2022
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10. Transcatheter Aortic Valve Replacement With the LOTUS Edge System: Early European Experience

Author

Armario, Xavier, Rosseel, Liesbeth, Kharbanda, Rajesh, Khogali, Saib, Abdel-Wahab, Mohamed, Van Mieghem, Nicolas M., Tchétché, Didier, Dumonteil, Nicolas, De Backer, Ole, Cotton, James, McGrath, Brian, Balakrishnan, Deepu, Ali, Noman, Farhan, Serdar, Joseph, Jubin, Charbonnier, Gaetan, Okuno, Taishi, McHugh, Fiachra, Hildick-Smith, David, Gilgen, Nicole, Hokken, Thijmen, Spence, Mark S., Frerker, Christian, Angelillis, Marco, Grygier, Marek, Cockburn, James, Bjursten, Henrik, Jeger, Raban V., Teles, Rui, Petronio, Anna S., Pilgrim, Thomas, Sinning, Jan-Malte, Nickenig, Georg, Søndergaard, Lars, Blackman, Daniel J., and Mylotte, Darren

Published
2021
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12. Predictors of early discharge after transcatheter aortic valve implantation: insight from the CoreValve ClinicalService

Author

Angelillis, Marco, Costa, Giulia, Giannini, Cristina, Fiorina, Claudia, Branca, Luca, Tamburino, Corrado, Barbanti, Marco, Gorla, Riccardo, Casenghi, Matteo, Bruschi, Giuseppe, Merlanti, Bruno, Montorfano, Matteo, Ferri, Luca A., Poli, Arnaldo, Regazzoli, Damiano, De Felice, Francesco, Maffeo, Diego, Trani, Carlo, Iadanza, Alessandro, and Petronio, Anna S.

Published
2022
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13. Impact of Discharge Location After Transcatheter Aortic Valve Replacement on 1-Year Outcomes in Women: Results From the WIN-TAVI Registry

Author

Mehilli, Julinda, Chandrasekhar, Jaya, Sartori, Samantha, Chieffo, Alaide, Petronio, Anna S., Lefèvre, Thierry, Presbitero, Patrizia, Capranzano, Piera, Tchetche, Didier, Iadanza, Alessandro, Sardella, Gennaro, Van Mieghem, Nicolas M., Meliga, Emanuela, Dumonteil, Nicolas, Fraccaro, Chiara, Trabattoni, Daniela, Jochheim, David, Zadrozny, Magda, Mikhail, Ghada W., Sharma, Samin, Ferrer, Maria C., Naber, Christoph, Kievit, Peter, Moalem, Kamilia, Baber, Usman, Snyder, Clayton, Sharma, Madhav, Morice, Marie C., and Mehran, Roxana

Published
2019
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16. Impact of diabetes on clinical outcome among elderly patients with acute coronary syndrome treated with percutaneous coronary intervention: insights from the ELDERLY ACS 2 trial

Author

De Luca, Giuseppe, Verdoia, Monica, Savonitto, Stefano, Piatti, Luigi, Grosseto, Daniele, Morici, Nuccia, Bossi, Irene, Sganzerla, Paolo, Tortorella, Giovanni, Cacucci, Michele, Murena, Ernesto, Toso, Anna, Bongioanni, Sergio, Ravera, Amelia, Corrada, Elena, Mariani, Matteo, Di Ascenzo, Leonardo, Petronio, Anna S., Cavallini, Claudio, Vitrella, Giancarlo, Antonicelli, Roberto, Rogacka, Renata, and De Servi, Stefano

Published
2020
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17. Transcatheter Mitral Valve Replacement Versus Medical Therapy for Secondary Mitral Regurgitation:A Propensity Score-Matched Comparison

Author

Ludwig, Sebastian, Conradi, Lenard, Cohen, David J., Coisne, Augustin, Scotti, Andrea, Abraham, William T., Ben Ali, Walid, Zhou, Zhipeng, Li, Yanru, Kar, Saibal, Duncan, Alison, Scott Lim, D., Adamo, Marianna, Redfors, Björn, Muller, David W.M., Webb, John G., Petronio, Anna S., Ruge, Hendrik, Nickenig, Georg, Sondergaard, Lars, Adam, Matti, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Andreas, Martin, Dahle, Gry, Walther, Thomas, Kempfert, Joerg, Tang, Gilbert H.L., Redwood, Simon, Taramasso, Maurizio, Praz, Fabien, Fam, Neil, Dumonteil, Nicolas, Obadia, Jean François, Von Bardeleben, Ralph Stephan, Rudolph, Tanja K., Reardon, Michael J., Metra, Marco, Denti, Paolo, Mack, Michael J., Hausleiter, Jörg, Asch, Federico M., Latib, Azeem, Lindenfeld, Joann, Modine, Thomas, Stone, Gregg W., Granada, Juan F., Ludwig, Sebastian, Conradi, Lenard, Cohen, David J., Coisne, Augustin, Scotti, Andrea, Abraham, William T., Ben Ali, Walid, Zhou, Zhipeng, Li, Yanru, Kar, Saibal, Duncan, Alison, Scott Lim, D., Adamo, Marianna, Redfors, Björn, Muller, David W.M., Webb, John G., Petronio, Anna S., Ruge, Hendrik, Nickenig, Georg, Sondergaard, Lars, Adam, Matti, Regazzoli, Damiano, Garatti, Andrea, Schmidt, Tobias, Andreas, Martin, Dahle, Gry, Walther, Thomas, Kempfert, Joerg, Tang, Gilbert H.L., Redwood, Simon, Taramasso, Maurizio, Praz, Fabien, Fam, Neil, Dumonteil, Nicolas, Obadia, Jean François, Von Bardeleben, Ralph Stephan, Rudolph, Tanja K., Reardon, Michael J., Metra, Marco, Denti, Paolo, Mack, Michael J., Hausleiter, Jörg, Asch, Federico M., Latib, Azeem, Lindenfeld, Joann, Modine, Thomas, Stone, Gregg W., and Granada, Juan F.

Abstract

Background: Transcatheter mitral valve replacement (TMVR) is an emerging therapeutic alternative for patients with secondary mitral regurgitation (MR). Outcomes of TMVR versus guideline-directed medical therapy (GDMT) have not been investigated for this population. This study aimed to compare clinical outcomes of patients with secondary MR undergoing TMVR versus GDMT alone. Methods: The CHOICE-MI registry (Choice of Optimal Transcatheter Treatment for Mitral Insufficiency) included patients with MR undergoing TMVR using dedicated devices. Patients with MR pathogeneses other than secondary MR were excluded. Patients treated with GDMT alone were derived from the control arm of the COAPT trial (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation). We compared outcomes between the TMVR and GDMT groups, using propensity score matching to adjust for baseline differences. Results: After propensity score matching, 97 patient pairs undergoing TMVR (72.9±8.7 years; 60.8% men; transapical access, 91.8%) versus GDMT (73.1±11.0 years; 59.8% men) were compared. At 1 and 2 years, residual MR was ≤1+ in all patients of the TMVR group compared with 6.9% and 7.7%, respectively, in those receiving GDMT alone (both P<0.001). The 2-year rate of heart failure hospitalization was significantly lower in the TMVR group (32.8% versus 54.4%; hazard ratio, 0.59 [95% CI, 0.35–0.99]; P=0.04). Among survivors, a higher proportion of patients were in the New York Heart Association functional class I or II in the TMVR group at 1 year (78.2% versus 59.7%; P=0.03) and at 2 years (77.8% versus 53.2%; P=0.09). Two-year mortality was similar in the 2 groups (TMVR versus GDMT, 36.8% versus 40.8%; hazard ratio, 1.01 [95% CI, 0.62–1.64]; P=0.98). Conclusions: In this observational comparison, over 2-year follow-up, TMVR using mostly transapical devices in patients with secondar, Background: Transcatheter mitral valve replacement (TMVR) is an emerging therapeutic alternative for patients with secondary mitral regurgitation (MR). Outcomes of TMVR versus guideline-directed medical therapy (GDMT) have not been investigated for this population. This study aimed to compare clinical outcomes of patients with secondary MR undergoing TMVR versus GDMT alone. Methods: The CHOICE-MI registry (Choice of Optimal Transcatheter Treatment for Mitral Insufficiency) included patients with MR undergoing TMVR using dedicated devices. Patients with MR pathogeneses other than secondary MR were excluded. Patients treated with GDMT alone were derived from the control arm of the COAPT trial (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation). We compared outcomes between the TMVR and GDMT groups, using propensity score matching to adjust for baseline differences. Results: After propensity score matching, 97 patient pairs undergoing TMVR (72.9±8.7 years; 60.8% men; transapical access, 91.8%) versus GDMT (73.1±11.0 years; 59.8% men) were compared. At 1 and 2 years, residual MR was ≤1+ in all patients of the TMVR group compared with 6.9% and 7.7%, respectively, in those receiving GDMT alone (both P<0.001). The 2-year rate of heart failure hospitalization was significantly lower in the TMVR group (32.8% versus 54.4%; hazard ratio, 0.59 [95% CI, 0.35-0.99]; P=0.04). Among survivors, a higher proportion of patients were in the New York Heart Association functional class I or II in the TMVR group at 1 year (78.2% versus 59.7%; P=0.03) and at 2 years (77.8% versus 53.2%; P=0.09). Two-year mortality was similar in the 2 groups (TMVR versus GDMT, 36.8% versus 40.8%; hazard ratio, 1.01 [95% CI, 0.62-1.64]; P=0.98). Conclusions: In this observational comparison, over 2-year follow-up, TMVR using mostly transapical devices in patients with secondary MR was associated with significant red

Published
2023

19. Transcatheter aortic valve replacement with or without anesthesiologist: results from a high-volume single center

Author

Angelillis, Marco, primary, Stazzoni, Laura, additional, Costa, Giulia, additional, Giannini, Cristina, additional, Primerano, Chiara, additional, Spontoni, Paolo, additional, Pieroni, Andrea, additional, Guarracino, Fabio, additional, Bertini, Pietro, additional, Baldassarri, Rubia, additional, De Carlo, Marco, additional, and Petronio, Anna S., additional

Published
2022
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21. Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Capodanno, Davide, Petronio, Anna S., Prendergast, Bernard, Eltchaninoff, Helene, Vahanian, Alec, Modine, Thomas, Lancellotti, Patrizio, Sondergaard, Lars, Ludman, Peter F., Tamburino, Corrado, Piazza, Nicolò, Hancock, Jane, Mehilli, Julinda, Byrne, Robert A., Baumbach, Andreas, Kappetein, Arie Pieter, Windecker, Stephan, Bax, Jeroen, and Haude, Michael

Published
2017
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24. Abstract 12919: Impact of Small Valve Size After Transcatheter Aortic Valve Implantation on 1-year Outcomes in Women: Results From the WIN-TAVI Registry

Author

Pivato, Carlo Andrea, primary, Cao, Davide, additional, Sartori, Samantha, additional, Snyder, Clayton, additional, Nicolas, Johny, additional, Chiarito, Mauro, additional, Tavennier, Annerieke, additional, Nardin, Matteo, additional, Sharma, Samin K, additional, Mehilli, Julinda, additional, Petronio, Anna S, additional, Morice, Marie c, additional, Chieffo, Alaide, additional, Dangas, George, additional, and Mehran, Roxana, additional

Published
2021
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25. Implantation of one, two or multiple MitraClips for transcatheter mitral valve repair: insights from a 1824-patient multicenter study

Author

GIORDANO, Arturo, primary, FERRARO, Paolo, additional, FINIZIO, Filippo, additional, BIONDI-ZOCCAI, Giuseppe, additional, DENTI, Paolo, additional, BEDOGNI, Francesco, additional, RUBBIO, Antonio P., additional, PETRONIO, Anna S., additional, BARTORELLI, Antonio L., additional, MONGIARDO, Annalisa, additional, GIORDANO, Salvatore, additional, DE FELICE, Francesco, additional, ADAMO, Marianna, additional, MONTORFANO, Matteo, additional, BALDI, Cesare, additional, TARANTINI, Giuseppe, additional, GIANNINI, Francesco, additional, RONCO, Federico, additional, MONTEFORTE, Ida, additional, VILLA, Emmanuel, additional, FERRARIO, Maurizio, additional, FIOCCA, Luigi, additional, CASTRIOTA, Fausto, additional, and TAMBURINO, Corrado, additional

Published
2021
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26. Transcatheter Aortic Valve Replacement With the LOTUS Edge System:Early European Experience

Author

Armario, Xavier, Rosseel, Liesbeth, Kharbanda, Rajesh, Khogali, Saib, Abdel-Wahab, Mohamed, Van Mieghem, Nicolas M., Tchétché, Didier, Dumonteil, Nicolas, De Backer, Ole, Cotton, James, McGrath, Brian, Balakrishnan, Deepu, Ali, Noman, Farhan, Serdar, Joseph, Jubin, Charbonnier, Gaetan, Okuno, Taishi, McHugh, Fiachra, Hildick-Smith, David, Gilgen, Nicole, Hokken, Thijmen, Spence, Mark S., Frerker, Christian, Angelillis, Marco, Grygier, Marek, Cockburn, James, Bjursten, Henrik, Jeger, Raban V., Teles, Rui, Petronio, Anna S., Pilgrim, Thomas, Sinning, Jan Malte, Nickenig, Georg, Søndergaard, Lars, Blackman, Daniel J., Mylotte, Darren, Armario, Xavier, Rosseel, Liesbeth, Kharbanda, Rajesh, Khogali, Saib, Abdel-Wahab, Mohamed, Van Mieghem, Nicolas M., Tchétché, Didier, Dumonteil, Nicolas, De Backer, Ole, Cotton, James, McGrath, Brian, Balakrishnan, Deepu, Ali, Noman, Farhan, Serdar, Joseph, Jubin, Charbonnier, Gaetan, Okuno, Taishi, McHugh, Fiachra, Hildick-Smith, David, Gilgen, Nicole, Hokken, Thijmen, Spence, Mark S., Frerker, Christian, Angelillis, Marco, Grygier, Marek, Cockburn, James, Bjursten, Henrik, Jeger, Raban V., Teles, Rui, Petronio, Anna S., Pilgrim, Thomas, Sinning, Jan Malte, Nickenig, Georg, Søndergaard, Lars, Blackman, Daniel J., and Mylotte, Darren

Abstract

Objectives: The aim of this study was to evaluate the short-term safety and efficacy of transcatheter aortic valve replacement (TAVR) with the LOTUS Edge system. Background: The LOTUS Edge system was commercially re-released in April 2019. The authors report the first European experience with this device. Methods: A multicenter, single-arm, retrospective registry was initiated to evaluate short-term clinical outcomes. Included cases are the first experience with this device and new implantation technique in Europe. Clinical, echocardiographic, and computed tomographic data were analyzed. Endpoints were defined according to Valve Academic Research Consortium-2 and were site reported. Results: Between April and November 2019, 286 consecutive patients undergoing TAVR with the LOTUS Edge system at 18 European centers were included. The mean age and Society of Thoracic Surgeons score were 81.2 ± 6.9 years and 5.2 ± 5.4%, respectively. Nearly one-half of all patients (47.9%) were considered to have complex anatomy. Thirty-day major adverse events included death (2.4% [n = 7]) and stroke (3.5% [n = 10]). After TAVR, the mean aortic valve area was 1.9 ± 0.9 cm2, and the mean transvalvular gradient was 11.9 ± 5.7 mm Hg. None or trace paravalvular leak (PVL) occurred in 84.4% and moderate PVL in 2.0%. There were no cases of severe PVL. New permanent pacemaker (PPM) implantation was required in 25.9% among all patients and 30.8% among PPM-naive patients. Conclusions: Early experience with the LOTUS Edge system demonstrated satisfactory short-term safety and efficacy, favorable hemodynamic data, and very low rates of PVL in an anatomically complex cohort. New PPM implantation remained high. Further study will evaluate if increasing operator experience with the device and new implantation technique can reduce the incidence of PPM implantation.

Published
2021

27. Threshold for calcium volume evaluation in patients with aortic valve stenosis:correlation with Agatston score

Author

Angelillis, Marco, Costa, Giulia, De Backer, Ole, Mochi, Veronica, Christou, Andrea, Giannini, Cristina, Spontoni, Paolo, De Carlo, Marco, Søndergaard, Lars, Miccoli, Mario, Petronio, Anna S, Angelillis, Marco, Costa, Giulia, De Backer, Ole, Mochi, Veronica, Christou, Andrea, Giannini, Cristina, Spontoni, Paolo, De Carlo, Marco, Søndergaard, Lars, Miccoli, Mario, and Petronio, Anna S

Abstract

BACKGROUND: The evaluation of aortic valve calcium burden is important when planning for transcatheter aortic valve implantation (TAVI). Although a robust golden standard methodology is available for calcium evaluation on noncontrast-enhanced (NCE) computed tomographic (CT) series, a standard reference for calcium assessment on contrast-enhanced CT series is currently lacking.METHODS: Two hundred and forty-four preprocedural CT scans from patients who had received TAVI were analysed. We correlated the aortic calcium volumes obtained on CE series at three thresholds [450, 850, and 'probe + 100' Hounsfield Units (HU)] with the Agatston score obtained on NCE scans. A subgroup analysis was performed taking into account the contrast enhancement of the left ventricular outflow tract (LVOT), with a prespecified cut-off of 300 HU.RESULTS: The overall population analysis showed higher correlation with the Agatston score using the 850 HU threshold (r = 0.45, P < 0.0001); no correlation was found with the 450 HU threshold, whilst the 'probe + 100' HU threshold showed a weaker correlation (r = 0.30, P < 0.0001). In patients with LVOT enhancement less than 300 HU, 450 HU showed the highest accuracy in calcium identification (r = 0.70, P < 0.0001), whereas in patients with LVOT enhancement of at least 300 HU, the most accurate threshold was 850 HU (r = 0.46, P < 0.0001).CONCLUSION: The thresholds for correct calcium identification using the automatic 3Mensio software depend on the contrast enhancement of aortic and cardiac structures, which can be estimated by measuring the HU in the LVOT. In patients with LVOT HU of less than 300, the correct threshold to be set in the software is 450 HU, whereas in patients with LVOT HU of at least 300 the correct threshold is 850 HU.

Published
2021

30. Long-term outcomes after transcatheter aortic valve replacement in nonagenarians: a multicenter age-based analysis

Author

Costa, Giuliano, primary, Valvo, Roberto, additional, Fiorina, Claudia, additional, Adamo, Marianna, additional, Giannini, Cristina, additional, Testa, Luca, additional, Bruschi, Giuseppe, additional, Poli, Arnaldo, additional, De Felice, Francesco, additional, Montorfano, Matteo, additional, Maffeo, Diego, additional, Iadanza, Alessandro, additional, Reimers, Bernhard, additional, Bedogni, Francesco, additional, Petronio, Anna S., additional, Tamburino, Corrado, additional, and Barbanti, Marco, additional

Published
2020
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31. Implantation of one, two or multiple MitraClip™ for transcatheter mitral valve repair: insights from a 1824-patient multicenter study.

Author

GIORDANO, Arturo, FERRARO, Paolo, FINIZIO, Filippo, BIONDI-ZOCCAI, Giuseppe, DENTI, Paolo, BEDOGNI, Francesco, RUBBIO, Antonio P., PETRONIO, Anna S., BARTORELLI, Antonio L., MONGIARDO, Annalisa, GIORDANO, Salvatore, FELICE, Francesco DE, ADAMO, Marianna, MONTORFANO, Matteo, BALDI, Cesare, TARANTINI, Giuseppe, GIANNINI, Francesco, RONCO, Federico, MONTEFORTE, Ida, and VILLA, Emmanuel

Published
2022
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33. Bicuspid aortic valve sizing for transcatheter aortic valve implantation:Development and validation of an algorithm based on multi-slice computed tomography

Author

Petronio, Anna S., Angelillis, Marco, De Backer, Ole, Giannini, Cristina, Costa, Giulia, Fiorina, Claudia, Castriota, Fausto, Bedogni, Francesco, Laborde, Jean C., Søndergaard, Lars, Petronio, Anna S., Angelillis, Marco, De Backer, Ole, Giannini, Cristina, Costa, Giulia, Fiorina, Claudia, Castriota, Fausto, Bedogni, Francesco, Laborde, Jean C., and Søndergaard, Lars

Abstract

Background: No indication are available for transcatheter aortic valve implantation (TAVI) sizing in bicuspid aortic valve (BAV). Aim of the study is to develop and validate a Multi-Slice Computed Tomography (MSCT)-based algorithm for transcatheter heart valve (THV) sizing in patients with stenotic BAV under evaluation for TAVI. Methods: A two steps method was applied: 1)evaluation of a cohort of 19 consecutive patients with type I BAV stenosis undergoing TAVI through pre and post-procedural MSCT, and development of an algorithm for THV sizing; 2)validation of the algorithm on a new cohort of 21 patients. Results: In the first cohort, a high correlation was found between the raphe-level area measured at pre-procedural MSCT and the smallest THV area measured at post-procedural MSCT (p < 0.001). Moreover, reduced THV expansion was observed among patients with higher calcium burden (p = 0.048). Then, a new algorithm for TAVI sizing in BAV was develop (CASPER: Calcium Algorithm Sizing for bicusPid Evaluation with Raphe). This algorithm is based on the reassessment of the perimeter/area derived annulus diameter, according to three main anatomical features: 1) the ratio between raphe length and annulus diameter; 2)calcium burden; 3)calcium distribution in relation to the raphe. The algorithm was then validated in a new cohort of 21 patients, achieving 100% of procedural success and excellent TAVI performance. Conclusion: MSCT assessment of raphe length, calcium burden and its distribution is of crucial relevance in the pre-procedural evaluation of patients with BAV. These anatomical features can be combined in a new and simple algorithm for TAVI sizing.

Published
2020

37. Efficacy and Safety of ProGlide Versus Prostar XL Vascular Closure Devices in Transcatheter Aortic Valve Replacement: The RISPEVA Registry.

Author

Berti, Sergio, Bedogni, Francesco, Giordano, Arturo, Petronio, Anna S., Iadanza, Alessandro, Bartorelli, Antonio L., Reimers, Bernard, Spaccarotella, Carmen, Trani, Carlo, Attisano, Tiziana, Cenname, Angela Marella, Sardella, Gennaro, Bonmassari, Roberto, Medda, Massimo, Tomai, Fabrizio, Tarantini, Giuseppe, Navarese, Eliano P., Marella Cenname, Angela, and Italian Society of Interventional Cardiology‐GISE†

Published
2020
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38. Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves: a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Capodanno, Davide, primary, Petronio, Anna S, additional, Prendergast, Bernard, additional, Eltchaninoff, Helene, additional, Vahanian, Alec, additional, Modine, Thomas, additional, Lancellotti, Patrizio, additional, Sondergaard, Lars, additional, Ludman, Peter F, additional, Tamburino, Corrado, additional, Piazza, Nicolò, additional, Hancock, Jane, additional, Mehilli, Julinda, additional, Byrne, Robert A, additional, Baumbach, Andreas, additional, Kappetein, Arie Pieter, additional, Windecker, Stephan, additional, Bax, Jeroen, additional, and Haude, Michael, additional

Published
2017
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39. Standardized definitions of structural deterioration and valve failure in assessing long-term durability of transcatheter and surgical aortic bioprosthetic valves:a consensus statement from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) endorsed by the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)

Author

Capodanno, Davide, Petronio, Anna S, Prendergast, Bernard, Eltchaninoff, Helene, Vahanian, Alec, Modine, Thomas, Lancellotti, Patrizio, Sondergaard, Lars, Ludman, Peter F, Tamburino, Corrado, Piazza, Nicolò, Hancock, Jane, Mehilli, Julinda, Byrne, Robert A, Baumbach, Andreas, Kappetein, Arie Pieter, Windecker, Stephan, Bax, Jeroen, Haude, Michael, Capodanno, Davide, Petronio, Anna S, Prendergast, Bernard, Eltchaninoff, Helene, Vahanian, Alec, Modine, Thomas, Lancellotti, Patrizio, Sondergaard, Lars, Ludman, Peter F, Tamburino, Corrado, Piazza, Nicolò, Hancock, Jane, Mehilli, Julinda, Byrne, Robert A, Baumbach, Andreas, Kappetein, Arie Pieter, Windecker, Stephan, Bax, Jeroen, and Haude, Michael

Published
2017

41. Impact of Discharge Location After Transcatheter Aortic Valve Replacement on 1-Year Outcomes in Women: Results From the WIN-TAVI Registry

Author

Mehilli, Julinda, Chandrasekhar, Jaya, Sartori, Samantha, Chieffo, Alaide, Petronio, Anna S., Lefèvre, Thierry, Presbitero, Patrizia, Capranzano, Piera, Tchetche, Didier, Iadanza, Alessandro, Sardella, Gennaro, Van Mieghem, Nicolas M., Meliga, Emanuela, Dumonteil, Nicolas, Fraccaro, Chiara, Trabattoni, Daniela, Jochheim, David, Zadrozny, Magda, Mikhail, Ghada, Sharma, Samin, Ferrer, Maria C., Naber, Christoph, Kievit, Peter, Moalem, Kamilia, Baber, Usman, Snyder, Clayton, Sharma, Madhav, Morice, Marie C., and Mehran, Roxana

Abstract

Several clinical and procedural factors determine outcomes after transcatheter aortic valve replacement (TAVR), but data are scarce on the impact of post-TAVR discharge disposition on long-term outcomes. We sought to analyse whether discharge location after TAVR is associated with 1-year outcomes in women undergoing contemporary TAVR.

Published
2024
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42. Optimal Implantation Depth and Adherence to Guidelines on Permanent Pacing to Improve the Results of Transcatheter Aortic Valve Replacement With the Medtronic CoreValve System

Author

Petronio, Anna S., primary, Sinning, Jan-Malte, additional, Van Mieghem, Nicolas, additional, Zucchelli, Giulio, additional, Nickenig, Georg, additional, Bekeredjian, Raffi, additional, Bosmans, Johan, additional, Bedogni, Francesco, additional, Branny, Marian, additional, Stangl, Karl, additional, Kovac, Jan, additional, Schiltgen, Molly, additional, Kraus, Stacia, additional, and de Jaegere, Peter, additional

Published
2015
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