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4 results on '"Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness [DISEASES]"'

1. 'Acute kidney injury in critically ill patients with COVID–19: The AKICOV multicenter study in Catalonia'

Author

de la Vega Sánchez, Arsenio, Navas Pérez, Ana Maria, Pérez Carrasco, Marcos, Torrens Sonet, María, Diaz Buendia, Yolanda, Ortiz Ballujera, Patricia, Institut Català de la Salut, [Sánchez AV, Pérez-Carrasco M] Servei de Medicina Intensiva, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca de Shock, Disfunció Orgànica i Ressuscitació (SODIR), Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Bellaterra, Spain. [Pérez AN] Critical Care Center, Parc Tauli Hospital Universitari, Institut d’Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell, Barcelona, Spain. [Sonet MT] Intensive Care Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain. [Buendia YD] Critical Care Department, Hospital del Mar, Barcelona, Spain. [Ballujera PO] Intensive Care Department, Hospital Universitari Doctor Josep Trueta de Girona, Girona, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crítica [ENFERMEDADES], Insuficiència renal aguda - Prognosi, enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales::insuficiencia renal::lesión renal aguda [ENFERMEDADES], virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], Ronyons - Malalties - Prognosi, Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Acute Kidney Injury [DISEASES], Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness [DISEASES], COVID-19 (Malaltia) - Complicacions
Abstract

Acute kidney injury; COVID-19; Catalonia Lesión renal aguda; COVID-19; Cataluña Lesió renal aguda; COVID-19; Catalunya This study describes the incidence, evolution and prognosis of acute kidney injury (AKI) in critical COVID-19 during the first pandemic wave. We performed a prospective, observational, multicenter study of confirmed COVID-19 patients admitted to 19 intensive care units (ICUs) in Catalonia (Spain). Data regarding demographics, comorbidities, drug and medical treatment, physiological and laboratory results, AKI development, need for renal replacement therapy (RRT) and clinical outcomes were collected. Descriptive statistics and logistic regression analysis for AKI development and mortality were used. A total of 1,642 patients were enrolled (mean age 63 (15.95) years, 67.5% male). Mechanical ventilation (MV) was required for 80.8% and 64.4% of these patients, who were in prone position, while 67.7% received vasopressors. AKI at ICU admission was 28.4% and increased to 40.1% during ICU stay. A total of 172 (10.9%) patients required RRT, which represents 27.8% of the patients who developed AKI. AKI was more frequent in severe acute respiratory distress syndrome (ARDS) ARDS patients (68% vs 53.6%, p

Published
2023

2. Pre-analytical and analytical procedures to avoid loss of vitamin C. Comment on: 'COVID-19: up to 82% critically ill patients had low vitamin C values'

Author

Luis Chiscano-Camón, Juan Carlos Ruiz-Rodriguez, Roser Ferrer, Sílvia Camós, Adolf Ruiz-Sanmartin, Ricard Ferrer, Institut Català de la Salut, [Chiscano-Camón L, Ruiz-Rodriguez JC, Ruiz-Sanmartin A, Ferrer R] Unitat de Cures Intensives, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca de Shock, Disfunció Orgànica i Ressuscitació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Vall d’Hebron Hospital Universitari, Barcelona, Spain. Departament de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain. [Ferrer R, Camós S] Servei de Bioquímica, Laboratoris Clínics, Vall d’Hebron Hospital Universitari, Barcelona, Spain, and Vall d'Hebron Barcelona Hospital Campus

Subjects
Vitamina C, Nutrition and Dietetics, compuestos orgánicos::ácidos carboxílicos::ácidos acíclicos::azúcares ácidos::ácido ascórbico [COMPUESTOS QUÍMICOS Y DROGAS], afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crítica [ENFERMEDADES], virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], Medicine (miscellaneous), Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], COVID-19 (Malaltia), Unitats de cures intensives, Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness [DISEASES], Organic Chemicals::Carboxylic Acids::Acids, Acyclic::Sugar Acids::Ascorbic Acid [CHEMICALS AND DRUGS]
Abstract

COVID-19; Vitamin C COVID-19; Vitamina C COVID-19; Vitamina C

Published
2022

3. Clinical nutrition issues in 2022: What is missing to trust supplemental parenteral nutrition (SPN) in ICU patients?

Author

Mette M. Berger, Rosa Burgos, Michael P. Casaer, Edoardo De Robertis, Juan Carlos Lopez Delgado, Vincent Fraipont, João Gonçalves-Pereira, Claude Pichard, Christian Stoppe, Institut Català de la Salut, [Berger MM] Lausanne University Hospital, Lausanne, Switzerland. [Burgos R] Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Casaer MP] Laboratory and Clinical Department of Intensive Care Medicine, KU Leuven, Leuven, Belgium. [De Robertis E] Intensive Care Service, Department of Surgical and Biomedical Science, University of Perugia, Perugia, Italy. [Lopez Delgado JC] Area de Vigilancia Intensiva (ICMiD), Hospital Clínic de Barcelona, Barcelona, Spain. [Fraipont V] Service of Intensive Care Medicine, Citadelle Hospital, Liège, Belgium, and Vall d'Hebron Barcelona Hospital Campus

Subjects
Adult, Clinical nutrition, Parenteral Nutrition, Critical Care, Critical Illness, Critical Care and Intensive Care Medicine, Trust, Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness [DISEASES], Critical Care Medicine, afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crítica [ENFERMEDADES], General & Internal Medicine, Nutrition care, Supplemental parenteral nutrition, Humans, Intensive care unit, Critically ill, Unitats de cures intensives, Otros calificadores::/terapia [Otros calificadores], Science & Technology, Other subheadings::/therapy [Other subheadings], terapéutica::métodos de alimentación::nutrición parenteral [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Health Care Facilities, Manpower, and Services::Health Facilities::Hospital Units::Intensive Care Units [HEALTH CARE], Intensive Care Units, Malalts en estat crític, instalaciones, servicios y personal de asistencia sanitaria::centros sanitarios::unidades hospitalarias::unidades de cuidados intensivos [ATENCIÓN DE SALUD], Therapeutics::Feeding Methods::Parenteral Nutrition [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], CRITICALLY-ILL ADULTS, Life Sciences & Biomedicine, Nutrició parenteral
Abstract

Clinical nutrition; Intensive care unit; Nutrition care Nutrició clínica; Unitat de cures intensives; Cura de la nutrició Nutrición Clínica; Unidad de cuidados intensivos; Cuidado de la nutrición A multidisciplinary group of international physicians involved in the medical nutrition therapy (MNT) of adult critically ill patients met to discuss the value, role, and open questions regarding supplemental parenteral nutrition (SPN) along with oral or enteral nutrition (EN), particularly in the intensive care unit (ICU) setting. This manuscript summarizes the discussions and results to highlight the importance of SPN as part of a comprehensive approach to MNT in critically ill adults and for researchers to generate new evidence based on well-powered randomized controlled trials (RCTs). The experts agreed on several key points: SPN has shown clinical benefits, resulting in this strategy being included in American and European guidelines. Nevertheless, its use is heterogeneous across European countries, due to the persistence of uncertainties, such as the optimal timing and the risk of overfeeding in absence of indirect calorimetry (IC), which results in divergent opinions and barriers to SPN implementation. Education is also insufficient. The experts agreed on actions needed to increase evidence quality on SPN use in specific patients at a given time point during acute critical illness or recovery. The organization of the Virtual Meeting that motivated this publication was funded by Baxter Healthcare SA. The authors received no financial support for the research, authorship, and/or publication of this article. MPC receives funding from the Research Foundation Flanders (FWO) (Grant No. 1832817N) and Onderzoeksraad, KU Leuven (Grant No. C24/17/070) and from the Private Charity Organization “Help Brandwonden Kids.

Published
2022

4. Different epidemiology of bloodstream infections in COVID-19 compared to non-COVID-19 critically ill patients: a descriptive analysis of the Eurobact II study

Author

Buetti, Niccolò, Tabah, Alexis, Loiodice, Ambre, Ruckly, Stéphane, Aslan, Abdullah Tarik, Montrucchio, Giorgia, Cortegiani, Andrea, Saltoglu, Nese, Kayaaslan, Bircan, Aksoy, Firdevs, Murat, Akova, Akdoğan, Özlem, Saracoglu, Kemal Tolga, Erdogan, Cem, Leone, Marc, Ferrer, Ricard, Paiva, José-Artur, Hayashi, Yoshiro, Ramanan, Mahesh, Conway Morris, Andrew, Barbier, François, Timsit, Jean-François, Lipman, Jeffrey, Litton, Edward, Palermo, Anna Maria, Yap, Timothy, Eroglu, Ege, Hosokawa, Koji, Yoshida, Hideki, Fujitani, Shigeki, Zand, Farid, Mahmoodpoor, Ata, Tabatabaei, Seyed Mohammad Nasirodin, Elrabi, Omar, Almekhlafi, Ghaleb A, Vidal, Gabriela, Aparicio, Marta, Alonzo, Irene, Namendys-Silva, Silvio A, Hermosillo, Mariana, Castillo, Roberto Alejandro, De Bus, Liesbet, De Waele, Jan, Hollevoet, Isabelle, De Schryver, Nicolas, Serck, Nicolas, Kovacevic, Pedja, Zlojutro, Biljana, Ruppe, Etienne, Montravers, Philippe, Dulac, Thierry, Castanera, Jérémy, Massri, Alexandre, Guesdon, Charlotte, Garcon, Pierre, Duprey, Matthieu, Philippart, François, Tran, Marc, Bruel, Cédric, Kalfon, Pierre, Badre, Gaëtan, Demeret, Sophie, Le Guennec, Loïc, Bassetti, Matteo, Giacobbe, Daniele, Sales, Gabriele, Daroui, Ivan, Lodi, Giovanni, Ippolito, Mariachiara, Bellina, Davide, Di Guardo, Andrea, Rocco, Monica, Fiorelli, Silvia, Mikstacki, Adam, Peichota, Mariusz, Pietraszek-Grzywaczewska, Iwona, Póvoa, Pedro, Krystopchuk, Andriy, Teresa, Ana, De Figueiredo, António Manuel Pereira, Botelho, Isabel, Costa, Vasco, Cunha, Rui Pedro, Gritsan, Alexey, Belskiy, Vladislav, Furman, Mikhail, Martinez, Maria, Casares, Vanessa, Arnillas, Maria Pilar Gracia, Bermudez, Rosana Munoz, Ubeda, Alejandro, Salgado, Maria, Maseda, Emilio, De La Rica, Alejandro Suarez, Blasco-Navalpotro, Miguel Angel, Gallego, Alberto Orejas, Prazak, Josef, Pagani, JL, Abed-Maillard, S, Iskit, Arzu Topeli, Mehtap, Selcuk, Ceyhun, Solakoğlu, Kalem, Ayşe Kaya, Kurt, Ibrahim, Telli, Murat, Ozturk, Barcin, Baykam, Nurcan, Karaali, Ridvan, Koksal, Iftihar, Bilir, Yeliz, Guzeldag, Seda, Ersoz, Gulden, Evik, Guliz, Bayindir, Yasar, Ersoy, Yasemin, Ercole, Ari, Raj, Ashok, Zormpa, Artemis, Tinaslanidis, George, Khade, Reena, Roshdy, Ashraf, Kannan, Santhana, Antrolikar, Supriya, Marsden, Nicholas, Attwood, Ben, Patel, Jamie, Gurjar, Mohan, Dsilva, Carol, Chandran, Jagadish, Sanousi, Bashir El, Saidahmed, Elfayadh, Hamid, Hytham KS, Buetti, Niccolò, Tabah, Alexi, Loiodice, Ambre, Ruckly, Stéphane, Aslan, Abdullah Tarik, Montrucchio, Giorgia, Cortegiani, Andrea, Saltoglu, Nese, Kayaaslan, Bircan, Aksoy, Firdev, Murat, Akova, Akdoğan, Özlem, Saracoglu, Kemal Tolga, Erdogan, Cem, Leone, Marc, Ferrer, Ricard, Paiva, José-Artur, Hayashi, Yoshiro, Ramanan, Mahesh, Conway Morris, Andrew, Barbier, Françoi, Timsit, Jean-François, Conway Morris, Andrew [0000-0002-3211-3216], Apollo - University of Cambridge Repository, Institut Català de la Salut, [Buetti N] Infection Control Program and WHO Collaborating Centre on Patient Safety, Geneva University Hospitals and Faculty of Medicine, Geneva, Switzerland. INSERM, IAME, Université Paris-Cité, Paris, France. [Tabah A] Intensive Care Unit, Redclife Hospital, Metro North Hospital and Health Services, Brisbane, QLD, Australia. Queensland University of Technology, Brisbane, QLD, Australia. Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia. [Loiodice A, Ruckly S] ICURESEARCH, Fonaine, France. [Aslan AT] Department of Internal Medicine, Hacettepe University, Sihhiye, Ankara, Turkey. [Montrucchio G] Department of Surgical Sciences, University of Turin, Turin, Italy. Department of Anaesthesia, Critical Care and Emergency, Città Della Salute e Della Scienza Hospital, Turin, Italy. [Ferrer R] Servei de Medicina Intensiva, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Grup de Recerca en Xoc, Disfunció Orgànica i Ressuscitació, Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, Timsit, Jean-Françoi, Lipman, Jeffrey, Litton, Edward, Palermo, Anna Maria, Yap, Timothy, Eroglu, Ege, Hosokawa, Koji, Yoshida, Hideki, Fujitani, Shigeki, Zand, Farid, Mahmoodpoor, Ata, Tabatabaei, Seyed Mohammad Nasirodin, Elrabi, Omar, Almekhlafi, Ghaleb A., Vidal, Gabriela, Aparicio, Marta, Alonzo, Irene, Namendys-Silva, Silvio A., Hermosillo, Mariana, Castillo, Roberto Alejandro, De Bus, Liesbet, De Waele, Jan, Hollevoet, Isabelle, De Schryver, Nicola, Serck, Nicola, Kovacevic, Pedja, Zlojutro, Biljana, Ruppe, Etienne, Montravers, Philippe, Dulac, Thierry, Castanera, Jérémy, Massri, Alexandre, Guesdon, Charlotte, Garcon, Pierre, Duprey, Matthieu, Philippart, Françoi, Tran, Marc, Bruel, Cédric, Kalfon, Pierre, Badre, Gaëtan, Demeret, Sophie, Le Guennec, Loïc, Bassetti, Matteo, Giacobbe, Daniele, Sales, Gabriele, Daroui, Ivan, Lodi, Giovanni, Ippolito, Mariachiara, Bellina, Davide, Di Guardo, Andrea, Rocco, Monica, Fiorelli, Silvia, Mikstacki, Adam, Peichota, Mariusz, Pietraszek-Grzywaczewska, Iwona, Póvoa, Pedro, Krystopchuk, Andriy, Teresa, Ana, de Figueiredo, António Manuel Pereira, Botelho, Isabel, Costa, Vasco, Cunha, Rui Pedro, Gritsan, Alexey, Belskiy, Vladislav, Furman, Mikhail, Martinez, Maria, Casares, Vanessa, Arnillas, Maria Pilar Gracia, Bermudez, Rosana Munoz, Ubeda, Alejandro, Salgado, Maria, Maseda, Emilio, De La Rica, Alejandro Suarez, Blasco-Navalpotro, Miguel Angel, Gallego, Alberto Oreja, Prazak, Josef, Pagani, J. L., Abed-Maillard, S., Iskit, Arzu Topeli, Mehtap, Selcuk, Ceyhun, Solakoğlu, Kalem, Ayşe Kaya, Kurt, Ibrahim, Telli, Murat, Ozturk, Barcin, Baykam, Nurcan, Karaali, Ridvan, Koksal, Iftihar, Bilir, Yeliz, Guzeldag, Seda, Ersoz, Gulden, Evik, Guliz, Bayindir, Yasar, Ersoy, Yasemin, Ercole, Ari, Raj, Ashok, Zormpa, Artemi, Tinaslanidis, George, Khade, Reena, Roshdy, Ashraf, Kannan, Santhana, Antrolikar, Supriya, Marsden, Nichola, Attwood, Ben, Patel, Jamie, Gurjar, Mohan, Dsilva, Carol, Chandran, Jagadish, Sanousi, Bashir El, Saidahmed, Elfayadh, and Hamid, Hytham K. S.

Subjects
Male, bloodstream infections, Other subheadings::Other subheadings::/epidemiology [Other subheadings], Critical Illness, COVID-19 (Malaltia) - Epidemiologia, RESISTANT ENTEROCOCCI, Bacteremia, Bloodstream infection, Critical Care and Intensive Care Medicine, Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Critical Illness [DISEASES], Cohort Studies, afecciones patológicas, signos y síntomas::procesos patológicos::atributos de la enfermedad::enfermedad crítica [ENFERMEDADES], Sepsis, virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], Medicine and Health Sciences, Humans, NCT03937245, Unitats de cures intensives, Aged, Cross Infection, Malalties bacterianes, infecciones bacterianas y micosis::infección::infección hospitalaria [ENFERMEDADES], Research, Otros calificadores::Otros calificadores::/epidemiología [Otros calificadores], COVID-19, Enterococcus, ICU-acquired, Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], Bacterial Infections and Mycoses::Infection::Cross Infection [DISEASES], Intensive Care Units, NCT, ICU, RNA
Abstract

Funder: European society of Intensive Care Medicine, Funder: European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Funder: Norva Dahlia foundation and the Redcliffe Hospital Private Practice Trust Fund, Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 and non-COVID-19 critically ill patients. Methods We used data from the Eurobact II study, a prospective observational multicontinental cohort study on HABSI treated in ICU. For the current analysis, we selected centers that included both COVID-19 and non-COVID-19 critically ill patients. We performed descriptive statistics between COVID-19 and non-COVID-19 in terms of patients’ characteristics, source of infection and microorganism distribution. We studied the association between COVID-19 status and mortality using multivariable fragility Cox models. Results A total of 53 centers from 19 countries over the 5 continents were eligible. Overall, 829 patients (median age 65 years [IQR 55; 74]; male, n = 538 [64.9%]) were treated for a HABSI. Included patients comprised 252 (30.4%) COVID-19 and 577 (69.6%) non-COVID-19 patients. The time interval between hospital admission and HABSI was similar between both groups. Respiratory sources (40.1 vs. 26.0%, p < 0.0001) and primary HABSI (25.4% vs. 17.2%, p = 0.006) were more frequent in COVID-19 patients. COVID-19 patients had more often enterococcal (20.5% vs. 9%) and Acinetobacter spp. (18.8% vs. 13.6%) HABSIs. Bacteremic COVID-19 patients had an increased mortality hazard ratio (HR) versus non-COVID-19 patients (HR 1.91, 95% CI 1.49–2.45). Conclusions We showed that the epidemiology of HABSI differed between COVID-19 and non-COVID-19 patients. Enterococcal HABSI predominated in COVID-19 patients. COVID-19 patients with HABSI had elevated risk of mortality. Trial registration ClinicalTrials.org number NCT03937245. Registered 3 May 2019.

Published
2022

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