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1. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

Alonso, A., Barrio Lopez, M.T., Basterra-Gortari, F.J., Benito Corchon, S., Bes-Rastrollo, M., Beunza, J.J., Carlos, S., Cervantes, S., de Irala, J., de la Rosa, P.A., de la Fuente, C., Donat-Vargas, C.L., Donazar, M., Fernandez Montero, A., Gea, A., Goni-Ochandorena, E., Guillen-Grima, F., Lahortiga, F., Llorca, J., Lopez del Burgo, C., Mari-Sanchıs, A., Marti, A., Mendonça, R., Nuñez-Cordoba, J.M., Pimenta, A.M., Rico, A., Ruiz Zambrana, A., Sayon-Orea, C., Toledo-Atucha, J., Vazquez Ruiz, Z., Zazpe Garcıa, I., Sánchez- Tainta, A., Buil-Cosiales, P., Díez-Espino, J., Sanjulian, B., Martínez, J.A., Serrano-Martínez, M., Extremera-Urabayen, J.V., Garcia-Pérez, L., Arroyo-Azpa, C., Barcena, A.F., Oreja-Arrayago, C., Lasanta-Sáez, M.J., Cia-Lecumberri, P., Elcarte-Lopez, T., Artal-Moneva, F., Esparza-López, J.M., Figuerido-Garmendia, E., Tabar-Sarrias, J.A., Fernández- Urzainqui, L., Ariz-Arnedo, M.J., Cabeza-Beunza, J.A., Pascual-Pascual, P., Martínez-Mazo, M.D., Arina-Vergara, E., Macua-Martínez, T., Pascual Pascual, P., Garcés Ducar, M.L., Martí Massó, R., Villanueva Moreno, R., Parra-Osés, A., Serra-Mir, M., Pérez-Heras, A., Viñas, C., Casas, R., Medina-Remon, A., Villanueva, P., Baena, J.M., García, M., Oller, M., Amat, J., Duaso, I., García, Y., Iglesias, C., Simón, C., Quinzavos, L., Parra, L., Liroz, M., Benavent, J., Clos, J., Pla, I., Amorós, M., Bonet, M.T., Martín, M.T., Sánchez, M.S., Altirriba, J., Manzano, E., Altés, A., Cofán, M., Valls-Pedret, C., Sala-Vila, A., Doménech, M., Bulló, M., Basora-Gallisa, J., González, R., Molina, C., Mena, G., Martínez, P., Ibarrola, N., Sorlí, J., García Roselló, J., Martin, F., Tort, N., Isach, A., Babio, N., Salas-Huetos, A., Becerra-Tomás, N., Rosique- Esteban, N., Hernandez, P., Canudas, S., Papandreou, C., Ferreira, C., Cabre, M., Mestres, G., Paris, F., Llauradó, M., Pedret, R., Basells, J., Vizcaino, J., Segarra, R., Giardina, S., Guasch-Ferré, M., Díaz-López, A., Fernández-Ballart, J., Balanza, R., Tello, S., Vila, J., de la Torre, R., Muñoz-Aguayo, D., Elosua, R., Marrugat, J., Schröder, H., Molina, N., Maestre, E., Rovira, A., Castañer, O., Farré, M., Sorli, J., Carrasco, P., Ortega-Azorín, C., Asensio, E.M., Osma, R., Barragán, R., Francés, F., Guillén, M., González, J.I., Sáiz, C., Portolés, O., Giménez, F.J., Coltell, O., Fernández-Carrión, R., Guillem-Sáiz, P., González-Monje, I., Quiles, L., Pascual, V., Riera, C., Pages, M.A., Godoy, D., Carratalá-Calvo, A., Sánchez-Navarro, S., Valero-Barceló, C., Salaverria, I., Hierro, T. del, Algorta, J., Francisco, S., San Vicente, J., Casi, A., Sanz, E., Felipe, I., Rekondo, J., Loma-Osorio, A., Fernandez-Crehuet, J., Garcia-Rodriguez, A., Wärnberg, J., Benitez Pont, R., Bianchi Alba, M., Navajas, R., Gómez-Huelgas, R., Martínez-González, J., Velasco García, V., de Diego Salas, J., Baca Osorio, A., Gil Zarzosa, J., Sánchez Luque, J.J., Vargas López, E., Romaguera, D., García-Valdueza, M., Proenza, A., Prieto, R., Frontera, G., Munuera, S., Vivó, M., Bestard, F., Munar, J.A., Coll, L., Fiol, F., Ginard, M., Jover, A., García, J., Santos-Lozano, J.M., Ortega-Calvo, M., Leal, M., Martínez, E., Mellado, L., Miró-Moriano, L., Domínguez-Espinaco, C., Vaquero- Diaz, S., Iglesias, P., Román, P., Corchado, Y., Lozano-Rodríguez, J.M., Lamuela-Raventós, R., López- Sabater, M.C., Castellote-Bargalló, A.I., Quifer-Rada, P., Tresserra-Rimbau, A., Alvarez-Pérez, J., Díez Benítez, E., Bautista Castaño, I., Maldonado Díaz, I., Sanchez-Villegas, A., Férnandez- Rodríguez, M.J., Sarmiendo de la Fe, F., Simón García, C., Falcón Sanabria, I., Macías Gutiérrez, B., Santana Santana, A.J., de la Cruz, E., Galera, A., Pintó-Salas, X., Trias, F., Sarasa, I., Rodríguez, M.A., Corbella, X., Corbella, E., Goday, A., Muñoz, M.A., Cabezas, C., Vinyoles, E., Rovira, M.A., Garcia, L., Baby, P., Ramos, A., Mengual, L., Roura, P., Yuste, M.C., Guarner, A., Santamaria, M.I., Mata, M., de Juan, C., Brau, A., Fernandez, M., Gutierrez, E., Murillo, C., Garcia, J., Tafalla, M., Bobe, I., Díaz, A., Araque, M., Solis, E., Cervello, T., Montull, I., Tur, J.A., Portillo, M.P., Sáez, G., Garcia-Arellano, Ana, Martínez-González, Miguel A., Ramallal, Raul, Salas-Salvadó, Jordi, Hébert, James R., Corella, Dolores, Shivappa, Nitin, Forga, Luis, Schröder, Helmut, Muñoz-Bravo, Carlos, Estruch, Ramón, Fiol, Miquel, Lapetra, José, Serra-Majem, Lluís, Ros, Emilio, Rekondo, Javier, Toledo, Estefanía, Razquin, Cristina, and Ruiz-Canela, Miguel

Published
2019
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2. La siniestralidad laboral en la población inmigrante de Navarra en el 2006: Una aproximación a sus causas

Author

Ángel Parra Osés, Vega García López, Jesús Fernández Baraibar, and José Ramón Ayestarán Ruiz Bazán

Subjects
Occupational injuries, immigrants workers, characteristics and causes, Medicine, Internal medicine, RC31-1245, Industrial medicine. Industrial hygiene, RC963-969
Abstract

Introducción: El cambio económico y social que está experimentando Navarra en las últimas décadas está asociado con la llegada de un flujo creciente de inmigrantes. El fenómeno migratorio plantea un gran número de desafíos: legislativos, políticos, culturales, sociales, sanitarios y por supuesto laborales. Desde el punto de vista laboral la incorporación de inmigrantes al mercado de trabajo ha supuesto, sin duda, aspectos positivos, pero también algunas disfunciones y problemas, siendo uno de ellos los altos niveles de siniestralidad que presenta este colectivo. Objetivos: Analizar y profundizar en las características y causas de la siniestralidad en este colectivo y los factores que podrían incidir en ella. Metodología: Estudio descriptivo - observacional tomando como base los datos del Registro de Accidentes de Trabajo del año 2006. Resultados: Para un 9,8% de trabajadores extranjeros, éstos sufren el 20% de los accidentes de trabajo( AT). Las mujeres extranjeras se accidentan casi 4 puntos menos en porcentaje relativo que las nacionales. La distribución de AT es similar en ambas poblaciones atendiendo a su gravedad, los trabajadores extranjeros sufrieron el 19,3% de los accidentes graves y el 15,8% de los mortales. En este colectivo los grupos de edades más jóvenes presentan porcentajes más elevados de siniestralidad. Por sectores económicos: una tercera parte de los accidentes en Agricultura y Construcción corresponden a trabajadores emigrantes. Su distribución porcentual es reflejo de la diferente ocupación sectorial de este colectivo, duplicando los porcentajes en los sectores agrícola y construcción en comparación con la población de acogida. En población extranjera la proporción de hombres que se accidentan es superior al de las mujeres en todos los sectores productivos, excepto en Servicios. Cerca de 80% de accidentes en población inmigrante acontece en puestos de baja cualificación o no cualificados y casi las tres cuartas partes de los sucesos se producen en trabajadores inmigrantes con menos de un año de antigüedad en el puesto. La forma de producción, descripción y localización de las lesiones y el agente material responsable presentan perfiles de distribución superponibles en ambos colectivos. En porcentaje relativo los accidentes de trabajo notificados por Empresas de Trabajo Temporal en inmigrantes superan a los comunicados en población autóctona y mientras que casi el 75% se dan en varones, una tercera parte corresponden a población trabajadora extranjera. Además mientras el peso relativo de los ocurridos en mujeres extranjeras con esta modalidad de contrato supera al de nativas, en varones ocurre al contrario. Los índices de incidencia de AT por sector de actividad son superiores en el colectivo extranjero frente a los índices en población total, incluso en aquellas actividades menos representadas. En población inmigrante tanto los índices de incidencia globales como los diferentes índices según gravedad se duplican con respecto a la población nacional. Estos índices son inferiores en los países UE en relación al resto de países no UE. Por zonas geográficas de origen superan el índice medio los trabajadores del Magreb, Europa Occidental y África y por países Marruecos, Argelia y Portugal. Conclusiones y discusión: Tal vez las condiciones de trabajo que se caracterizan por la excesiva temporalidad, la frecuente subcontratación, el elevado índice de rotación (casi las tres cuartas partes de los accidentados extranjeros llevaban menos de un año en el puesto de trabajo) hacen que proporcionalmente el número de extranjeros con escasa experiencia y falta de adaptación sea todavía mayor que en el conjunto de la población. Es posible que la inestabilidad y precariedad laboral que afectan al colectivo inmigrante pudieran influir en su mayor incidencia. Otros trabajos a nivel nacional e internacional confirman tal aumento en los índices de incidencia. Analizar si este exceso de accidentalidad se debe a factores ocupacionales, tareas de mayor riesgo o bien es debida a factores de índole cultural, idiomática o adaptativos (tiempo de permanencia en nuestro país) son factores que se abordan en la discusión.Introducction: The economical and social changes Navarra is suffering during the last decades, is connected with the increasing immigration income rates. This aspect supposes different and huge legal, political, cultural, social, sanitary and of course professional challenges. Professionally speaking the big immigration income rates have, of course, advantages but have also some problems and dysfunctions as the very high accident levels this collective is suffering. Objetives: Analyzing and widening the accident’s characteristics and reasons and studying the possible causes Methodology: Descriptive and observation study by analyzing the Working Accident Register Year 2006. Results: At the moment a 9,8% of the total workers are foreign workers. These foreign workers have a 20% of the total working accident rate (WAR). Foreign working women have 4% less of the WAR than the local working women .If we talk about the seriousness of the accidents; the WAR average is similar between the foreign and the local workers. Foreign workers suffer the 19,3% of the grave accidents and 15,8% of the fatal ones. The under-aged working groups have a higher % of working accidents. If we study the different economical sectors, the results are the following: One-third of the accidents occurred in the Agriculture and Construction sector are suffered by immigrant workers. The reason is that immigrant workers cover a very wide range of sectors, being double as local workers in these both mentioned sectors. Immigrant men workers accident rate is higher than the immigrant women workers accident rate in all the sectors, except the non-productive industries. Almost the 80% of the working accidents suffered by the immigrant population occurred in the low level or not level qualification jobs and almost three quarters of the casualties are less than one year experimented workers. The accident’s happenings are, for both profiles, similar. The relative percent of the working accidents disclosed by the Casual Job Search Companies is higher for the immigrant population as for the local one. Almost the 75% is suffered by men workers and one-third by foreign workers. The relative percent of the working accidents disclosed by the Casual Job Search Companies is also higher for the foreign working women but lower for foreign working men. The incidence rate classified by activity sector is always higher for the foreign collective, even the less represented activity sectors. The immigrant population’s accident rate is double not only for the global rate but also for all the other rates classified by seriousness. These rates are lower for the EU countries as for the NO-EU countries. The highest rates are found in the following areas: Maghreb, Occidental Europe and Africa. The countries classification is the following: Morocco, Algeria and Portugal. Conclusion and discussions: Perhaps the too temporal working conditions or the too frequent subcontracting working conditions or the too frequent rotary conditions connote a higher rate of non-experience or non-adapted immigrant workers. Perhaps this inconstancy or this predicament acts on the working accident rate. Other national and international works corroborate the accident rate increase. The search of the accident rate’s source: working or risk factors or cultural, idiomatic or adaption factors will be under discussion.

Published
2008

4. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

L. Parra, Luis V. García, Cinta Valls-Pedret, Patricia Guillem-Saiz, Josep A. Tur, María P. Portillo, J. Vila, Estefanía Toledo, R. Martí Massó, E. de la Cruz, José I. González, J. de Irala, L. Garcia-Pérez, Simona Giardina, J.A. Cabeza-Beunza, I. Bautista Castaño, R. Osma, Alejandro Diaz, Ana Jover, M. Mata, Laura Quiles, Elena Martinez, T. Macua-Martínez, T. Elcarte-Lopez, Daniel Muñoz-Aguayo, Andrés Díaz-López, I. Duaso, Christopher Papandreou, L. Mellado, Manuel Leal, Carlos Ferreira, M.L. Garcés Ducar, M.J. Férnandez Rodríguez, I. Falcón Sanabria, P. Pascual-Pascual, L. Mengual, M.T. Martín, V. Velasco García, C. Simón García, G. Mestres, R. Benítez Pont, M. Ginard, Manuel Ortega-Calvo, L. Fernández Urzainqui, Susana Munuera, A. Fernandez Montero, James R. Hébert, E. Maestre, J. Amat, Miquel Fiol, Antonio García-Rodríguez, M. Vivó, Ernest Vinyoles, A. Ramos, B. Macías Gutiérrez, A. Casi, F. Artal-Moneva, M.A. Rodríguez, I. González-Monje, I. Maldonado Díaz, José V. Sorlí, Miguel-Angel Muñoz, Josep Basora-Gallisà, Dolores Corella, J. Gil Zarzosa, J. Alvarez-Pérez, M.A. Rovira, Mònica Bulló, Maira Bes-Rastrollo, P. Iglesias, N. Tort, Adriano Marçal Pimenta, S. Sánchez-Navarro, J. San Vicente, Pilar Buil-Cosiales, José Alfredo Martínez, E. Gutierrez, A. Proenza, Cristina Razquin, Paola Quifer-Rada, J. Marrugat, A.J. Santana Santana, Olga Castañer, Javier Rekondo, F. Trias, Magí Farré, J.M. Lozano-Rodriguez, Carlos Muñoz-Bravo, Marta Evelia Aparicio García, G. Mena, Leticia Miró-Moriano, Anna Tresserra-Rimbau, Z. Vazquez Ruiz, S. Tello, P. Baby, M.J. Ariz-Arnedo, J. García, M. Donazar, Emili Corbella, Jordi Salas-Salvadó, J. Fernandez-Crehuet, C. Simón, J.M. Baena, C. Murillo, Amelia Marti, A. Brau, H. Schröder, Rafael Balanza, C. Iglesias, R. Pedret, C. Oreja-Arrayago, J. Clos, R. Villanueva Moreno, V. Pascual, C. Lopez del Burgo, Raquel Pimienta González, Mercè Serra-Mir, Luis Forga, Helmut Schröder, Alex Medina-Remón, Javier Díez-Espino, C. de Juan, M. Amorós, M.D. Martínez-Mazo, D. Godoy, Olga Portolés, L. Quinzavos, Nancy Babio, Nerea Becerra-Tomás, J. Altirriba, P. Martínez, Carolina Donat-Vargas, N. Rosique Esteban, P. Villanueva, Ramon Estruch, Albert Goday, M. Tafalla, Alfredo Gea, R. de la Torre, F. Martin, B. Sanjulián, Ana García-Arellano, Y. García, Alvaro Alonso, P. Román, M. García-Valdueza, M.T. Barrio Lopez, N. Ibarrola, Marisa Guillén, Francisco Javier Basterra-Gortari, M. Liroz, Joan Fernández-Ballart, I. Bobe, F. Paris, P. Pascual Pascual, E. Manzano, Ricardo Gómez-Huelgas, F. Sarmiendo de la Fe, José Lapetra, R. Navajas, J. García Roselló, E. Sanz, F. Fiol, A. Baca Osorio, A.I. Castellote-Bargalló, J.V. Extremera-Urabayen, Carmen Sayón-Orea, I. Montull, Xavier Corbella, Sebastián Cervantes, T. del Hierro, Nitin Shivappa, E. Solis, Jorge M. Núñez-Córdoba, I. Zazpe Garcıa, A. Parra-Osés, Rosa Casas, Francisco Guillén-Grima, A. Altés, F.J. Giménez, Itziar Salaverria, M.C. Yuste, Carolina Ortega-Azorín, A. Carratalá-Calvo, E. Vargas López, F. Bestard, Eva M. Asensio, Paula Carrasco, T. Cervello, J.J. Sánchez Luque, Raul Ramallal, A. Isach, Ariadna Rovira, Juan Carlos Martínez-González, M. Oller, Francesc Francés, Lluis Serra-Majem, Montse Cofán, J.M. Santos-Lozano, Julia Wärnberg, C. Arroyo-Azpa, I. Sarasa, E. Díez Benítez, Guiem Frontera, J. Rekondo, Manuel Serrano-Martínez, Ana Pérez-Heras, Emilio Ros, I. Felipe, C. Domínguez-Espinaco, Carmen Saiz, M.I. Santamaría, Francisca Lahortiga, E. Figuerido-Garmendia, I. Pla, J. Benavent, Marta Guasch-Ferré, J.A. Tabar-Sarrias, P. Hernandez, X. Pintó-Salas, Rafel M. Prieto, C. Valero-Barceló, Albert Salas-Huetos, A. Loma-Osorio, M.T. Bonet, E. Arina-Vergara, P.A. de la Rosa, C. de la Fuente, J. Basells, Jaime Algorta, R. Segarra, A. Guarner, Rocío Barragán, S. Vaquero Diaz, Roberto Elosua, A. Sánchez Tainta, M. Bianchi Alba, Pilar Roura, Casandra Riera, Ana Galera, N. Molina, P. Cia-Lecumberri, J.A. Munar, Jesús Vizcaíno, J. de Diego Salas, J.M. Esparza-López, R. M. Lamuela-Raventos, A. Ruiz Zambrana, Aleix Sala-Vila, Amelia Marí-Sanchis, L. Coll, A.F. Barcena, Miguel Ángel Martínez-González, J.J. Beunza, Y. Corchado, M.S. Sánchez, Mónica Doménech, J. Toledo-Atucha, E. Goni-Ochandorena, Silvia Canudas, Raquel de Deus Mendonça, M. Cabre, O. Coltell, Miguel Ruiz-Canela, Javier Llorca, M.A. Pages, M.C. López Sabater, Guillermo T. Sáez, S. Francisco, M. Araque, Almudena Sánchez-Villegas, Silvia Carlos, Carmen Cabezas, Dora Romaguera, M. Llauradó, S. Benito Corchon, A. Rico, M.J. Lasanta-Sáez, C. Molina, C. Viñas, Rebeca Fernández-Carrión, M.A. Fernandez, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Centro Nacional de Investigaciones Cardiovasculares (España), European Commission, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat de Catalunya, Generalitat Valenciana, and Diputación Foral de Navarra

Subjects
Adult, Male, 0301 basic medicine, medicine.medical_specialty, Mediterranean diet, 030209 endocrinology & metabolism, Context (language use), Type 2 diabetes, Diet, Mediterranean, Critical Care and Intensive Care Medicine, Dietary inflammatory index, Body Mass Index, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Internal medicine, Humans, Medicine, Obesity, Prospective Studies, Mortality, Prospective cohort study, Randomized Controlled Trials as Topic, Inflammation, 030109 nutrition & dietetics, Nutrition and Dietetics, business.industry, Smoking, Hazard ratio, Middle Aged, medicine.disease, Diet, C-Reactive Protein, Diabetes Mellitus, Type 2, Cohort, Patient Compliance, Cohort studies, Female, business, CRP, Cohort study
Abstract

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts., [Design]: We assessed 18,566 participants in the “Seguimiento Universidad de Navarra” (SUN) cohort followed-up during 188,891 person-years and 6790 participants in the “PREvencion con DIeta MEDiterránea” (PREDIMED) randomized trial representing 30,233 person-years of follow-up. DII scores were calculated in both cohorts from validated FFQs. Higher DII scores corresponded to more proinflammatory diets. A total of 230 and 302 deaths occurred in SUN and PREDIMED, respectively. In a random-effect meta-analysis we included 12 prospective studies (SUN, PREDIMED and 10 additional studies) that assessed the association between DII scores and all-cause mortality., [Results]: After adjusting for a wide array of potential confounders, the comparison between extreme quartiles of the DII showed a positive and significant association with all-cause mortality in both the SUN (hazard ratio [HR] = 1.85; 95% CI: 1.15, 2.98; P-trend = 0.004) and the PREDIMED cohort (HR = 1.42; 95% CI: 1.00, 2.02; P-trend = 0.009). In the meta-analysis of 12 cohorts, the DII was significantly associated with an increase of 23% in all-cause mortality (95% CI: 16%–32%, for the highest vs lowest category of DII)., [Conclusion]: Our results provide strong and consistent support for the hypothesis that a pro-inflammatory diet is associated with increased all-cause mortality. The SUN cohort and PREDIMED trial were registered at clinicaltrials.gov as NCT02669602 and at isrctn.com as ISRCTN35739639, respectively., Supported by the official funding agency for biomedical research of the Spanish Government, Instituto de Salud Carlos III (ISCIII), through grants provided to research networks specifically developed for the trial (RTIC G03/140, to R.E.; RTIC RD 06/0045, to Miguel A. Martínez-González) and through Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigación Sanitaria–Fondo Europeo de Desarrollo Regional (Proyecto de Investigación (PI) 04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, P11/02505, PI13/00462, PI13/00615, PI13/01090, PI14/01668, PI14/01798, PI14/01764), Ministerio de Ciencia e Innovación (Recursos y teconologia agroalimentarias(AGL)-2009-13906-C02 and AGL2010-22319-C03 and AGL2013-49083-C3-1- R), Fundación Mapfre 2010, the Consejería de Salud de la Junta de Andalucía (PI0105/2007), the Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana (Generalitat Valenciana Ayuda Complementaria (GVACOMP) 06109, GVACOMP2010-181, GVACOMP2011-151), Conselleria de Sanitat y, PI14/01764 AP; Atención Primaria (CS) 2010-AP-111, and CS2011-AP-042), and Regional Government of Navarra (P27/2011).). Drs. Shivappa and Hébert were supported by grant number R44DK103377 from the United States National Institute of Diabetes and Digestive and Kidney Diseases.

Published
2019

5. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

Garcia-Arellano, Ana, primary, Martínez-González, Miguel A., additional, Ramallal, Raul, additional, Salas-Salvadó, Jordi, additional, Hébert, James R., additional, Corella, Dolores, additional, Shivappa, Nitin, additional, Forga, Luis, additional, Schröder, Helmut, additional, Muñoz-Bravo, Carlos, additional, Estruch, Ramón, additional, Fiol, Miquel, additional, Lapetra, José, additional, Serra-Majem, Lluís, additional, Ros, Emilio, additional, Rekondo, Javier, additional, Toledo, Estefanía, additional, Razquin, Cristina, additional, Ruiz-Canela, Miguel, additional, Alonso, A., additional, Barrio Lopez, M.T., additional, Basterra-Gortari, F.J., additional, Benito Corchon, S., additional, Bes-Rastrollo, M., additional, Beunza, J.J., additional, Carlos, S., additional, Cervantes, S., additional, de Irala, J., additional, de la Rosa, P.A., additional, de la Fuente, C., additional, Donat-Vargas, C.L., additional, Donazar, M., additional, Fernandez Montero, A., additional, Gea, A., additional, Goni-Ochandorena, E., additional, Guillen-Grima, F., additional, Lahortiga, F., additional, Llorca, J., additional, Lopez del Burgo, C., additional, Mari-Sanchıs, A., additional, Marti, A., additional, Mendonça, R., additional, Nuñez-Cordoba, J.M., additional, Pimenta, A.M., additional, Rico, A., additional, Ruiz Zambrana, A., additional, Sayon-Orea, C., additional, Toledo-Atucha, J., additional, Vazquez Ruiz, Z., additional, Zazpe Garcıa, I., additional, Sánchez- Tainta, A., additional, Buil-Cosiales, P., additional, Díez-Espino, J., additional, Sanjulian, B., additional, Martínez, J.A., additional, Serrano-Martínez, M., additional, Extremera-Urabayen, J.V., additional, Garcia-Pérez, L., additional, Arroyo-Azpa, C., additional, Barcena, A.F., additional, Oreja-Arrayago, C., additional, Lasanta-Sáez, M.J., additional, Cia-Lecumberri, P., additional, Elcarte-Lopez, T., additional, Artal-Moneva, F., additional, Esparza-López, J.M., additional, Figuerido-Garmendia, E., additional, Tabar-Sarrias, J.A., additional, Fernández- Urzainqui, L., additional, Ariz-Arnedo, M.J., additional, Cabeza-Beunza, J.A., additional, Pascual-Pascual, P., additional, Martínez-Mazo, M.D., additional, Arina-Vergara, E., additional, Macua-Martínez, T., additional, Pascual Pascual, P., additional, Garcés Ducar, M.L., additional, Martí Massó, R., additional, Villanueva Moreno, R., additional, Parra-Osés, A., additional, Serra-Mir, M., additional, Pérez-Heras, A., additional, Viñas, C., additional, Casas, R., additional, Medina-Remon, A., additional, Villanueva, P., additional, Baena, J.M., additional, García, M., additional, Oller, M., additional, Amat, J., additional, Duaso, I., additional, García, Y., additional, Iglesias, C., additional, Simón, C., additional, Quinzavos, L., additional, Parra, L., additional, Liroz, M., additional, Benavent, J., additional, Clos, J., additional, Pla, I., additional, Amorós, M., additional, Bonet, M.T., additional, Martín, M.T., additional, Sánchez, M.S., additional, Altirriba, J., additional, Manzano, E., additional, Altés, A., additional, Cofán, M., additional, Valls-Pedret, C., additional, Sala-Vila, A., additional, Doménech, M., additional, Bulló, M., additional, Basora-Gallisa, J., additional, González, R., additional, Molina, C., additional, Mena, G., additional, Martínez, P., additional, Ibarrola, N., additional, Sorlí, J., additional, García Roselló, J., additional, Martin, F., additional, Tort, N., additional, Isach, A., additional, Babio, N., additional, Salas-Huetos, A., additional, Becerra-Tomás, N., additional, Rosique- Esteban, N., additional, Hernandez, P., additional, Canudas, S., additional, Papandreou, C., additional, Ferreira, C., additional, Cabre, M., additional, Mestres, G., additional, Paris, F., additional, Llauradó, M., additional, Pedret, R., additional, Basells, J., additional, Vizcaino, J., additional, Segarra, R., additional, Giardina, S., additional, Guasch-Ferré, M., additional, Díaz-López, A., additional, Fernández-Ballart, J., additional, Balanza, R., additional, Tello, S., additional, Vila, J., additional, de la Torre, R., additional, Muñoz-Aguayo, D., additional, Elosua, R., additional, Marrugat, J., additional, Schröder, H., additional, Molina, N., additional, Maestre, E., additional, Rovira, A., additional, Castañer, O., additional, Farré, M., additional, Sorli, J., additional, Carrasco, P., additional, Ortega-Azorín, C., additional, Asensio, E.M., additional, Osma, R., additional, Barragán, R., additional, Francés, F., additional, Guillén, M., additional, González, J.I., additional, Sáiz, C., additional, Portolés, O., additional, Giménez, F.J., additional, Coltell, O., additional, Fernández-Carrión, R., additional, Guillem-Sáiz, P., additional, González-Monje, I., additional, Quiles, L., additional, Pascual, V., additional, Riera, C., additional, Pages, M.A., additional, Godoy, D., additional, Carratalá-Calvo, A., additional, Sánchez-Navarro, S., additional, Valero-Barceló, C., additional, Salaverria, I., additional, Hierro, T. del, additional, Algorta, J., additional, Francisco, S., additional, San Vicente, J., additional, Casi, A., additional, Sanz, E., additional, Felipe, I., additional, Rekondo, J., additional, Loma-Osorio, A., additional, Fernandez-Crehuet, J., additional, Garcia-Rodriguez, A., additional, Wärnberg, J., additional, Benitez Pont, R., additional, Bianchi Alba, M., additional, Navajas, R., additional, Gómez-Huelgas, R., additional, Martínez-González, J., additional, Velasco García, V., additional, de Diego Salas, J., additional, Baca Osorio, A., additional, Gil Zarzosa, J., additional, Sánchez Luque, J.J., additional, Vargas López, E., additional, Romaguera, D., additional, García-Valdueza, M., additional, Proenza, A., additional, Prieto, R., additional, Frontera, G., additional, Munuera, S., additional, Vivó, M., additional, Bestard, F., additional, Munar, J.A., additional, Coll, L., additional, Fiol, F., additional, Ginard, M., additional, Jover, A., additional, García, J., additional, Santos-Lozano, J.M., additional, Ortega-Calvo, M., additional, Leal, M., additional, Martínez, E., additional, Mellado, L., additional, Miró-Moriano, L., additional, Domínguez-Espinaco, C., additional, Vaquero- Diaz, S., additional, Iglesias, P., additional, Román, P., additional, Corchado, Y., additional, Lozano-Rodríguez, J.M., additional, Lamuela-Raventós, R., additional, López- Sabater, M.C., additional, Castellote-Bargalló, A.I., additional, Quifer-Rada, P., additional, Tresserra-Rimbau, A., additional, Alvarez-Pérez, J., additional, Díez Benítez, E., additional, Bautista Castaño, I., additional, Maldonado Díaz, I., additional, Sanchez-Villegas, A., additional, Férnandez- Rodríguez, M.J., additional, Sarmiendo de la Fe, F., additional, Simón García, C., additional, Falcón Sanabria, I., additional, Macías Gutiérrez, B., additional, Santana Santana, A.J., additional, de la Cruz, E., additional, Galera, A., additional, Pintó-Salas, X., additional, Trias, F., additional, Sarasa, I., additional, Rodríguez, M.A., additional, Corbella, X., additional, Corbella, E., additional, Goday, A., additional, Muñoz, M.A., additional, Cabezas, C., additional, Vinyoles, E., additional, Rovira, M.A., additional, Garcia, L., additional, Baby, P., additional, Ramos, A., additional, Mengual, L., additional, Roura, P., additional, Yuste, M.C., additional, Guarner, A., additional, Santamaria, M.I., additional, Mata, M., additional, de Juan, C., additional, Brau, A., additional, Fernandez, M., additional, Gutierrez, E., additional, Murillo, C., additional, Garcia, J., additional, Tafalla, M., additional, Bobe, I., additional, Díaz, A., additional, Araque, M., additional, Solis, E., additional, Cervello, T., additional, Montull, I., additional, Tur, J.A., additional, Portillo, M.P., additional, and Sáez, G., additional

Published
2019
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6. Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

Author

Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Centro Nacional de Investigaciones Cardiovasculares (España), European Commission, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat de Catalunya, Generalitat Valenciana, Diputación Foral de Navarra, García-Arellano, Ana, Martínez-González, Miguel Ángel, Ramallal, Raúl, Salas-Salvadó, Jordi, Hébert, James R., Corella, Dolores, Shivappa, Nitin, Forga, Luis, Schröder, Helmut, Muñoz-Bravo, C., Estruch, Ramón, Hernández, P., Murillo, C., Mestres, G., Mengual, L., Serra-Majem, Lluis, Juan, C.de, Romaguera, Dora, Ruiz-Canela, Miguel, Vizcaíno, J., Bautista Castaño, I., Mendonça, Raquel Bicudo Deus, Farré, M., Basora-Gallisa, J., Barrio López, M.T., Buil-Cosiales, Pilar, Sarmiendo de la Fe, F., Medina-Remón, Alexander, Sánchez Luque, J. J., Sorlí, J., Cervantes, S., Pérez-Heras, A., Gil Zarzosa, J., Villanueva Moreno, R., Goni-Ochandorena, E., Lasanta-Sáez, M.J., Cia-Lecumberri, P., Fernandez-Urzainqui, L., Sáiz, C., Schroder, H., Carrasco, P., Doménech, M., Mellado, L., Toledo-Atucha, J., Guillen-Grima, F., Marrugat, J., Sáez, G., Ruiz Zambrana, A., Miró-Moriano, L., Zazpe Garcia, I, Godoy, D., Segarra, R., Toledo, Estefania, Molina, C., Loma-Osorio, A., Martínez, E., Bulló, Mònica, Vinyoles, E., Estremera-Urabayen, J. V., García, Y., Simón, C., Amorós, M., Navajas, R., Sánchez-Navarro, S., Casi, A., Pimenta, A. M., Tabar-Sarrias, J. A., Cruz, E. de la, Pascual-Pascual, P., Riera, C., García-Pérez, L., Carratalá-Calvo, A., Sanchez-Tainta, A., Ariz-Arnedo, M.J., Galera, A., Arina-Vergara, E., Martínez-González, José, Munuera, S., Francés, F., Felipe, I., Martínez, P., Gea, A., Díaz-López, A., Santana Santana, A. J., Serra-Mir, Mercè, Ros, Emilio, Villanueva, P., Becerra-Tomás, Nerea, Rosique-Esteban, N., Papandreou, Christopher, García, J., Prieto, R., Bestard, F., Osma, R., Baena, J.M., Figuerido-Garmendia, E., Pla, I., Tafalla, M., Benavent, J., Sánchez, M. S., Proenza, A., García, M., Vivo, M., Garcés Ducar, M. L., Bonet, M.T., Casas, Ricard, Bobe, I., Altés, A., Ginard, M., Díez-Espino, Javier, López-Sabater, M. C., Wärnberg, Julia, Valls-Pedret, C., Basells, J., Serrano-Martinez, M., Giménez, F.J., Velasco García, V., González, R., González, J. I., Barragán, Rocío, Martín, F., Muñoz-Aguayo, Daniel, Elosua, Roberto, Rovira, A., Fernández-Rodríguez, M. J., Román, Pablo, Quifer-Rada, P., Fernández-Crehuet, Joaquín, Llorca, J., Tort, N., Iglesias, P., Clos, J., Ferreira, C., Lopez del Burgo, C., Llauradó, M., Sarasa, Iziar, Jover, A., Altirriba, J., Bianchi Alba, M., Lahortiga, F., García-Rodriguez, A., Cabeza-Beunza, J. A., Fernández-Ballart, J., Pascual, V., Pages, M.A., del Hierro, T., Mata, M., Corbella, X., García, L., Maestre, E., Barcena, A. F., Sorlí, José V., Carlos, Silvia, Balanza, R., Rodríguez, M. A., Pedret, R., Castañer, Olga, Oreja-Arrayago, C., Ortega-Azorín, Carolina, Cervello, T., Maldonado Díaz, I., Ramos, A., Gómez-Huelgas, R., García Roselló, J., Benito Crochon, S., Arroyo-Azpa, C., Guillén, M., Martín, M. T., Coltell, O., García-Valdueza, M., Frontera, G., Fernandez Montero, A., Rosa, Pedro Antonio de la, Tur, Josep A., Díez Benítez, E., Razquin, Cristina, Molina, N., Salaverria Lete, Itziar, Amat, J., Alonso, A., Araque, M., Fernández-Carrión, Rebeca, Montull, I., Asensio, Eva M., Algorta, J., Portolés, Olga, Duaso, I., Sanz, E., Donat-Vargas, Carolina, Sayón-Orea, Carmen, Guarner, A., Fiol, F., Guasch‐Ferré, Marta, Simón García, C., Oller, M., Brau, A., Benítez Pont, R., Sánchez-Villegas, A., Diego Salas, J. de, Domínguez-Espinaco, C., Vaquero-Díaz, S., Lozano-Rodríguez, J.M., Marti, A., Núñez-Córdoba, J.M., Vázquez Ruiz, Z., Roura, P., Babio, Nancy, Baca Osorio, A., Valero-Barcelo, C., Basterra-Gortari, F. Javier, Salas-Huetos, A., Munar, J.A., Elcarte-Lopez, T., Donazar, M., San Vicente, J., Santamaria, M. I., Isach, A., Yuste, M. C., Ortega-Calvo, Manuel, Pintó-Salas, X., Trias, Ferrán, Muñoz, Miguel Ángel, Viñas, C., Esparza-López, J.M., Martínez-Mazo, M.D., Bes-Rastrollo, M., Vila, J., Castellote-Bargalló, Ana I., Leal, M., Artal-Moneva, F., Coll, L., Lamuela-Raventós, Rosa M., Torre, Rafael de la, Tresserra-Rimbau, A., Quinzavos, L., Sanjulian, B., Macua-Martínez, T., Irala, J. de, Sala-Vila, Aleix, Tello, S., Beunza, J.J., Francisco, S., Falcón Sanabria, I., Díaz, A., Solis, E., Lapetra, José, Mena, G., Liroz, M., Manzano, E., Corchado, Y., Goday, A., Gonzaláz-Monje, I., Rovira, M.A., Iglesias, C., Macías Gutiérrez, B., Parra, L., Álvarez-Pérez, J., Cabezas, C., Quiles, L., Baby, P., Ibarrola-Jurado, Nuria, Cabre, M., Parra-Osés, A., Cofán, Montserrat, Fuente, Carmen de la, Santos-Lozano, J. M., Guillem-Saiz, P., Martínez, J. A., Fernández, M., Mari-Sanchıs, A., Rico, A., Giardina, S., Canudas, Silvia, Paris, F., Marti Massó, R., Gutierrez, E., Corbella, Emili, Fiol, Miquel, Vargas López, E., Portillo, María P., Rekondo, Javier, Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y Nutrición (España), Centro Nacional de Investigaciones Cardiovasculares (España), European Commission, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Junta de Andalucía, Generalitat de Catalunya, Generalitat Valenciana, Diputación Foral de Navarra, García-Arellano, Ana, Martínez-González, Miguel Ángel, Ramallal, Raúl, Salas-Salvadó, Jordi, Hébert, James R., Corella, Dolores, Shivappa, Nitin, Forga, Luis, Schröder, Helmut, Muñoz-Bravo, C., Estruch, Ramón, Hernández, P., Murillo, C., Mestres, G., Mengual, L., Serra-Majem, Lluis, Juan, C.de, Romaguera, Dora, Ruiz-Canela, Miguel, Vizcaíno, J., Bautista Castaño, I., Mendonça, Raquel Bicudo Deus, Farré, M., Basora-Gallisa, J., Barrio López, M.T., Buil-Cosiales, Pilar, Sarmiendo de la Fe, F., Medina-Remón, Alexander, Sánchez Luque, J. J., Sorlí, J., Cervantes, S., Pérez-Heras, A., Gil Zarzosa, J., Villanueva Moreno, R., Goni-Ochandorena, E., Lasanta-Sáez, M.J., Cia-Lecumberri, P., Fernandez-Urzainqui, L., Sáiz, C., Schroder, H., Carrasco, P., Doménech, M., Mellado, L., Toledo-Atucha, J., Guillen-Grima, F., Marrugat, J., Sáez, G., Ruiz Zambrana, A., Miró-Moriano, L., Zazpe Garcia, I, Godoy, D., Segarra, R., Toledo, Estefania, Molina, C., Loma-Osorio, A., Martínez, E., Bulló, Mònica, Vinyoles, E., Estremera-Urabayen, J. V., García, Y., Simón, C., Amorós, M., Navajas, R., Sánchez-Navarro, S., Casi, A., Pimenta, A. M., Tabar-Sarrias, J. A., Cruz, E. de la, Pascual-Pascual, P., Riera, C., García-Pérez, L., Carratalá-Calvo, A., Sanchez-Tainta, A., Ariz-Arnedo, M.J., Galera, A., Arina-Vergara, E., Martínez-González, José, Munuera, S., Francés, F., Felipe, I., Martínez, P., Gea, A., Díaz-López, A., Santana Santana, A. J., Serra-Mir, Mercè, Ros, Emilio, Villanueva, P., Becerra-Tomás, Nerea, Rosique-Esteban, N., Papandreou, Christopher, García, J., Prieto, R., Bestard, F., Osma, R., Baena, J.M., Figuerido-Garmendia, E., Pla, I., Tafalla, M., Benavent, J., Sánchez, M. S., Proenza, A., García, M., Vivo, M., Garcés Ducar, M. L., Bonet, M.T., Casas, Ricard, Bobe, I., Altés, A., Ginard, M., Díez-Espino, Javier, López-Sabater, M. C., Wärnberg, Julia, Valls-Pedret, C., Basells, J., Serrano-Martinez, M., Giménez, F.J., Velasco García, V., González, R., González, J. I., Barragán, Rocío, Martín, F., Muñoz-Aguayo, Daniel, Elosua, Roberto, Rovira, A., Fernández-Rodríguez, M. J., Román, Pablo, Quifer-Rada, P., Fernández-Crehuet, Joaquín, Llorca, J., Tort, N., Iglesias, P., Clos, J., Ferreira, C., Lopez del Burgo, C., Llauradó, M., Sarasa, Iziar, Jover, A., Altirriba, J., Bianchi Alba, M., Lahortiga, F., García-Rodriguez, A., Cabeza-Beunza, J. A., Fernández-Ballart, J., Pascual, V., Pages, M.A., del Hierro, T., Mata, M., Corbella, X., García, L., Maestre, E., Barcena, A. F., Sorlí, José V., Carlos, Silvia, Balanza, R., Rodríguez, M. A., Pedret, R., Castañer, Olga, Oreja-Arrayago, C., Ortega-Azorín, Carolina, Cervello, T., Maldonado Díaz, I., Ramos, A., Gómez-Huelgas, R., García Roselló, J., Benito Crochon, S., Arroyo-Azpa, C., Guillén, M., Martín, M. T., Coltell, O., García-Valdueza, M., Frontera, G., Fernandez Montero, A., Rosa, Pedro Antonio de la, Tur, Josep A., Díez Benítez, E., Razquin, Cristina, Molina, N., Salaverria Lete, Itziar, Amat, J., Alonso, A., Araque, M., Fernández-Carrión, Rebeca, Montull, I., Asensio, Eva M., Algorta, J., Portolés, Olga, Duaso, I., Sanz, E., Donat-Vargas, Carolina, Sayón-Orea, Carmen, Guarner, A., Fiol, F., Guasch‐Ferré, Marta, Simón García, C., Oller, M., Brau, A., Benítez Pont, R., Sánchez-Villegas, A., Diego Salas, J. de, Domínguez-Espinaco, C., Vaquero-Díaz, S., Lozano-Rodríguez, J.M., Marti, A., Núñez-Córdoba, J.M., Vázquez Ruiz, Z., Roura, P., Babio, Nancy, Baca Osorio, A., Valero-Barcelo, C., Basterra-Gortari, F. Javier, Salas-Huetos, A., Munar, J.A., Elcarte-Lopez, T., Donazar, M., San Vicente, J., Santamaria, M. I., Isach, A., Yuste, M. C., Ortega-Calvo, Manuel, Pintó-Salas, X., Trias, Ferrán, Muñoz, Miguel Ángel, Viñas, C., Esparza-López, J.M., Martínez-Mazo, M.D., Bes-Rastrollo, M., Vila, J., Castellote-Bargalló, Ana I., Leal, M., Artal-Moneva, F., Coll, L., Lamuela-Raventós, Rosa M., Torre, Rafael de la, Tresserra-Rimbau, A., Quinzavos, L., Sanjulian, B., Macua-Martínez, T., Irala, J. de, Sala-Vila, Aleix, Tello, S., Beunza, J.J., Francisco, S., Falcón Sanabria, I., Díaz, A., Solis, E., Lapetra, José, Mena, G., Liroz, M., Manzano, E., Corchado, Y., Goday, A., Gonzaláz-Monje, I., Rovira, M.A., Iglesias, C., Macías Gutiérrez, B., Parra, L., Álvarez-Pérez, J., Cabezas, C., Quiles, L., Baby, P., Ibarrola-Jurado, Nuria, Cabre, M., Parra-Osés, A., Cofán, Montserrat, Fuente, Carmen de la, Santos-Lozano, J. M., Guillem-Saiz, P., Martínez, J. A., Fernández, M., Mari-Sanchıs, A., Rico, A., Giardina, S., Canudas, Silvia, Paris, F., Marti Massó, R., Gutierrez, E., Corbella, Emili, Fiol, Miquel, Vargas López, E., Portillo, María P., and Rekondo, Javier

Abstract

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts., [Design]: We assessed 18,566 participants in the “Seguimiento Universidad de Navarra” (SUN) cohort followed-up during 188,891 person-years and 6790 participants in the “PREvencion con DIeta MEDiterránea” (PREDIMED) randomized trial representing 30,233 person-years of follow-up. DII scores were calculated in both cohorts from validated FFQs. Higher DII scores corresponded to more proinflammatory diets. A total of 230 and 302 deaths occurred in SUN and PREDIMED, respectively. In a random-effect meta-analysis we included 12 prospective studies (SUN, PREDIMED and 10 additional studies) that assessed the association between DII scores and all-cause mortality., [Results]: After adjusting for a wide array of potential confounders, the comparison between extreme quartiles of the DII showed a positive and significant association with all-cause mortality in both the SUN (hazard ratio [HR] = 1.85; 95% CI: 1.15, 2.98; P-trend = 0.004) and the PREDIMED cohort (HR = 1.42; 95% CI: 1.00, 2.02; P-trend = 0.009). In the meta-analysis of 12 cohorts, the DII was significantly associated with an increase of 23% in all-cause mortality (95% CI: 16%–32%, for the highest vs lowest category of DII)., [Conclusion]: Our results provide strong and consistent support for the hypothesis that a pro-inflammatory diet is associated with increased all-cause mortality. The SUN cohort and PREDIMED trial were registered at clinicaltrials.gov as NCT02669602 and at isrctn.com as ISRCTN35739639, respectively.

Published
2019

7. Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

Author

Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Tresserra-Rimbau, A., Amat, J., García Roselló, J., Sanchez-Villegas, A., Álvarez-Pérez, J., Amorós, M., Cervello, T., Díez Benítez, E., Rovira, M.A., Altirriba, J., Sáiz, C., Mata, M., Bautista-Castaño, Inmaculada, Maldonado Díaz, I., Fernández-Rodríguez, M. J., Duaso, I., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Sáez, G., Corbella, E., de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, Sánchez-Ruiz, D., Schröder, H., Jurado-Ruiz, E., Portillo, M.P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, O., Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual, V., García-Arellano, A., Fernandez, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Casas, R., Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Martín, M.T., Vargas López, E., Medina-Remón, A., Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Tabar-Sarrias, J.A., Pages, M.A., Rebholz, C.M., Fernández-Urzainqui, L., Ariz-Arnedo, M.J., San Vicente, J., Martínez, P., Cabeza-Beunza, J.A., Simón, C., Rekondo, J., Sánchez, M.S., Pascual-Pascual, P., Martínez-Mazo, M.D., Arina-Vergara, E., Godoy, D., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martin, F., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., de la Torre, Rafael, Muñoz-Aguayo, D., Murillo, C., Fernández-Carrión, R., Rodríguez, M.A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Rovira, A., González, R., Castañer, O., Farré, M., Sanz, E., García, J., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, C., Romaguera, D., Roura, P., Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Munar, J.A., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fiol, F., del Hierro, T., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., Gómez-Gracia, Enrique, Montull, I., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Miró-Moriano, L., De la Fuente-Arrillaga, C., Oller, M., Domínguez-Espinaco, C., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Santamaria, M.I., Salas-Huetos, A., Galera, A., Vinyoles, E., Castellote-Bargalló, A. I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), and Junta de Andalucía

Subjects
Adult, Male, Pediatrics, medicine.medical_specialty, Diastole, Medicine (miscellaneous), 030204 cardiovascular system & hematology, Mediterranean, 03 medical and health sciences, 0302 clinical medicine, Animal science, Glycemic load, SUN cohort, medicine, Humans, 030212 general & internal medicine, Intervention trial, Prospective cohort study, Potatoes, Generalized estimating equation, Aged, Solanum tuberosum, Aged, 80 and over, Nutrition and Dietetics, Increase blood pressure, business.industry, Incidence (epidemiology), PREDIMED study, Middle Aged, Diet, Blood pressure, Spain, Hypertension, Female, business
Abstract

5 Tablas, Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension. Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations. Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means±SDs) of 42.7±13.3 y for men and 35.1± 10.7 y for women. In PREDIMED, generalized estimating equations adjusted for lifestyle and dietary characteristics were used to assess changes in BP across quintiles of total potato consumption during a 4-y follow-up. Controlled BP values (systolic BP < 140 mm Hg and diastolic BP < 90 mm Hg) during follow-up were also assessed. For SUN, multivariateadjusted HRs for incident hypertension during a mean 6.7-y follow-up were calculated. Results: In PREDIMED, the total potato intake was 81.9 ± 40.6 g/d. No overall differences in systolic or diastolic BP changes were detected based on consumption of potatoes. For total potatoes, the mean difference in change between quintile 5 (highest intake) and quintile 1 (lowest intake) in systolic BP after multivariate adjustment was 20.90 mm Hg (95% CI: -2.56, 0.76 mm Hg; P-trend = 0.1) and for diastolic BP was 20.02 mm Hg (95% CI: -0.93, 0.89 mm Hg; P-trend = 0.8). In SUN, the total potato consumption was 52.7 ± 33.6 g/d, and no significant association between potato consumption and hypertension incidence was observed in the fully adjusted HR for total potato consumption (quintile 5 compared with quintile 1: 0.98; 95% CI: 0.80, 1.19; P-trend = 0.8). Conclusions: Potato consumption is not associated with changes over 4 y in blood pressure among older adults in Spain or with the risk of hypertension among Spanish adults., Supported by the official funding agency for biomedical research of the Spanish Government, Instituto de Salud Carlos III through grants provided to research networks specifically developed for the trial (RTIC G03/140, to RE; RTIC RD 06/0045, to MAM-G) and through Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn), and by grants from Centro Nacional de Investigaciones Cardiovasculares (CNIC 06/2007), Fondo de Investigación Sanitaria–Fondo Europeo de Desarrollo Regional [Proyecto de Investigación (PI) 04-2239, PI 05/2584, CP06/00100, PI07/0240, PI07/1138, PI07/0954, PI 07/0473, PI10/01407, PI10/02658, PI11/01647, P11/02505 and PI13/00462], Ministerio de Ciencia e Innovación [Recursos y teconologia agroalimentarias (AGL)-2009-13906-C02 and AGL2010-22319-C03 and AGL2013-49083-C3-1-R], Fundación Mapfre 2010, the Consejería de Salud de la Junta de Andalucía (PI0105/2007), the Public Health Division of the Department of Health of the Autonomous Government of Catalonia, Generalitat Valenciana [Generalitat Valenciana Ayuda Complementaria (GVACOMP) 06109, GVACOMP2010-181, GVACOMP2011-151], Conselleria de Sanitat y AP; Atención Primaria (CS) 2010-AP-111 and CS2011-AP-042, and Regional Government of Navarra (P27/2011).

Published
2017

8. Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

Author

Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), Junta de Andalucía, Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Rovira, M.A., Tabar-Sarrias, J.A., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Pages, M.A., Altirriba, J., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Rebholz, C.M., Munar, J.A., Sáiz, C., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fernández-Urzainqui, L., Fiol, F., del Hierro, T., Mata, M., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., García, J., Gómez-Gracia, Enrique, Montull, I., Ariz-Arnedo, M.J., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., Bautista-Castaño, Inmaculada, García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., San Vicente, J., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Maldonado Díaz, I., Miró-Moriano, L., De la Fuente-Arrillaga, C., Rovira, A., Oller, M., Domínguez-Espinaco, C., Martínez, P., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., Fernández-Rodríguez, M. J., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Cabeza-Beunza, J.A., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Duaso, I., Santamaria, M.I., Salas-Huetos, A., Galera, A., Simón, C., Vinyoles, E., Castellote-Bargalló, Ana I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Rekondo, J., Sáez, G., Corbella, Emili, de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, R., Sánchez-Ruiz, D., Tresserra-Rimbau, A., Schröder, H., Jurado-Ruíz, Enrique, Portillo, María P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sánchez, M.S., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, Olga, Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual-Pascual, P., Pascual, V., García-Arellano, A., Fernández, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Martínez-Mazo, M.D., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Arina-Vergara, E., Casas, Ricard, Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Godoy, D., Martín, M. T., Vargas López, E., Medina-Remón, Alexander, Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martín, F., Amat, J., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., García Roselló, J., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Sanchez-Villegas, A., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., Álvarez-Pérez, J., de la Torre, Rafael, Muñoz-Aguayo, Daniel, Murillo, C., Fernández-Carrión, R., Rodríguez, M. A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Amorós, M., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Cervello, T., González, R., Castañer, O., Farré, M., Sanz, E., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, Carolina, Romaguera, D., Díez Benítez, E., Roura, P., Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), Junta de Andalucía, Hu, E.A., Martínez-González, Miguel Ángel, Salas-Salvadó, J., Corella, D., Ros, E., Fitó, Montserrat, García-Rodriguez, A., Estruch, R., Arós, F., Fiol, M., Lapetra, José, Asensio, E.M., Vázquez-Ruiz, Z., Canudas, S., Osma, R., Barragán, R., Muñoz, M.A., Martínez-González, J., Razquin, C., Valero-Barceló, C., Rovira, M.A., Tabar-Sarrias, J.A., Felipe, I., Francés, F., Guillén, M., González, J.I., Macías Gutiérrez, B., Tafalla, M., Bulló, M., Salaverria, I., Loma-Osorio, A., Baca Osorio, A., Pages, M.A., Altirriba, J., Munuera, S., Alonso, A., Sorlí, J., Vivó, M., Benitez Pont, R., Llauradó, M., Bestard, F., Montero Romero, Emilio, Molina, C., Rebholz, C.M., Munar, J.A., Sáiz, C., Cofán, M., Papandreou, C., Frontera, G., Coll, L., Quiles, L., Isach, A., Bes-Rastrollo, M., Perona, Javier S., Fernández-Urzainqui, L., Fiol, F., del Hierro, T., Mata, M., Ginard, M., Jover, A., Liroz, M., Parra-Osés, A., García, J., Gómez-Gracia, Enrique, Montull, I., Ariz-Arnedo, M.J., Santos-Lozano, J.M., Ortega-Calvo, M., Valls-Pedret, C., Bautista-Castaño, Inmaculada, García, M., Leal, M., Gil Zarzosa, J., Rico, A., Serra-Mir, M., Martínez, E., San Vicente, J., Mellado, L., Babio, N., Santana Santana, A.J., Benavent, J., Maldonado Díaz, I., Miró-Moriano, L., De la Fuente-Arrillaga, C., Rovira, A., Oller, M., Domínguez-Espinaco, C., Martínez, P., Bianchi Alba, M., Vaquero-Diaz, S., Iglesias, P., Cabezas, C., Sala-Vila, A., Fernández-Rodríguez, M. J., de la Cruz, E., Román, P., Corchado, Y., Solis, E., Cabeza-Beunza, J.A., Clos, J., Lozano-Rodríguez, J.M., Mestres, G., García-García, M., Lamuela-Raventós, Rosa M., López-Sabater, M.C., Duaso, I., Santamaria, M.I., Salas-Huetos, A., Galera, A., Simón, C., Vinyoles, E., Castellote-Bargalló, Ana I., Quifer-Rada, P., Gea, A., Pérez-Heras, A., Doménech, M., Becerra-Tomás, Nerea, Trias, F., García, L., Brau, A., Rekondo, J., Sáez, G., Corbella, Emili, de Diego Salas, J., Fernández-Montero, A., Yuste, M.C., Prieto, R., Pérez-de-Ciriza, P., Bobe, I., Navajas, R., Sánchez-Ruiz, D., Tresserra-Rimbau, A., Schröder, H., Jurado-Ruíz, Enrique, Portillo, María P., Buil-Cosiales, P., Sarmiendo de la Fe, F., Sánchez Luque, J.J., Ferreira, C., Zazpe, I., Díez-Espino, Javier, Sarasa, I., Sánchez, M.S., Sanjulian, B., Marti, A., Sorlí, J.V., Portolés, Olga, Martínez, J. Alfredo, Baby, P., Ibarrola-Jurado, Nuria, Serrano-Martínez, M., Sánchez-Tainta, A., Fernández-Crehuet, Joaquín, Pascual-Pascual, P., Pascual, V., García-Arellano, A., Fernández, M., Paris, F., Giménez, F.J., Basteara-Gortari, J., Extremera-Urabayen, J.V., Benítez Pont, R., Viñas, C., Algorta, J., Martínez-Mazo, M.D., Garcia-Pérez, L., Serra-Majem, L., Bonet, M.T., Riera, C., Arroyo-Azpa, C., Guarner, A., Sola-Larraza, A., Barcena, F., García, Y., Gutiérrez-Bedmar, M., Arina-Vergara, E., Casas, Ricard, Oreja-Arrayago, C., Lasanta-Sáez, M.J., Mena, G., Francisco, S., Cia-Lecumberri, P., García-Valdueza, M., Diáz, A., Elcarte-Lopez, T., Artal-Moneva, F., Godoy, D., Martín, M. T., Vargas López, E., Medina-Remón, Alexander, Iglesias, C., Esparza-López, J.M., Figuerido-Garmendia, E., Cabre, M., Coltell, O., Wärnberg, J., Ruiz-Gutiérrez, Valentina, Villanueva, P., Quinzavos, L., Manzano, E., Martín, F., Amat, J., de Juan, C., Basells, J., Pla, I., Tur, J.A., Vizcaino, J., Basora-Gallisa, J., Núñez-Córdoba, J.M., Segarra, R., Hernández, P., Araque, M., García Roselló, J., Giardina, S., Macua-Martínez, T., Gutierrez, E., Toledo, E., Pedret, R., Guasch-Ferré, Marta, Baena, J.M., Pintó, Xavier, Díaz-López, A., Rosique-Esteban, N., Sanchez-Villegas, A., Fernández-Ballart, J., Parra, L., Velasco García, V., Balanza, R., Tello, S., Ramos, A., Simón García, C., Vila, J., Altés, A., Proenza, A., Álvarez-Pérez, J., de la Torre, Rafael, Muñoz-Aguayo, Daniel, Murillo, C., Fernández-Carrión, R., Rodríguez, M. A., Elosua, R., Tort, N., Casi, A., Falcón Sanabria, I., Marrugat, J., Amorós, M., Ruiz-Canela, M., Carratalá-Calvo, A., Mengual, L., Guillem-Saiz, P., Molina, N., Maestre, E., Gómez-Huelgas, R., Corbella, X., Cervello, T., González, R., Castañer, O., Farré, M., Sanz, E., González-Monje, I., Sánchez-Navarro, S., Carrasco, P., Ortega-Azorín, Carolina, Romaguera, D., Díez Benítez, E., and Roura, P.

Abstract

Background: Potatoes have a high glycemic load but also antioxidants, vitamins, and minerals. It is unclear what mechanisms are involved in relation to their effect on blood pressure (BP) and hypertension. Objectives: This study aimed to assess the association between potato consumption, BP changes, and the risk of hypertension in 2 Spanish populations. Methods: Separate analyses were performed in PREDIMED (PREvención con DIeta MEDiterránea), a multicenter nutrition intervention trial of adults aged 55-80 y, and the SUN (Seguimiento Universidad de Navarra) project, a prospective cohort made up of university graduates and educated adults with ages (means±SDs) of 42.7±13.3 y for men and 35.1± 10.7 y for women. In PREDIMED, generalized estimating equations adjusted for lifestyle and dietary characteristics were used to assess changes in BP across quintiles of total potato consumption during a 4-y follow-up. Controlled BP values (systolic BP < 140 mm Hg and diastolic BP < 90 mm Hg) during follow-up were also assessed. For SUN, multivariateadjusted HRs for incident hypertension during a mean 6.7-y follow-up were calculated. Results: In PREDIMED, the total potato intake was 81.9 ± 40.6 g/d. No overall differences in systolic or diastolic BP changes were detected based on consumption of potatoes. For total potatoes, the mean difference in change between quintile 5 (highest intake) and quintile 1 (lowest intake) in systolic BP after multivariate adjustment was 20.90 mm Hg (95% CI: -2.56, 0.76 mm Hg; P-trend = 0.1) and for diastolic BP was 20.02 mm Hg (95% CI: -0.93, 0.89 mm Hg; P-trend = 0.8). In SUN, the total potato consumption was 52.7 ± 33.6 g/d, and no significant association between potato consumption and hypertension incidence was observed in the fully adjusted HR for total potato consumption (quintile 5 compared with quintile 1: 0.98; 95% CI: 0.80, 1.19; P-trend = 0.8). Conclusions: Potato consumption is not associated with changes over 4 y in blood pressure among o

Published
2017

9. Lesiones premalignas y malignas en cirugía menor de un centro de salud. Las apariencias engañan

Author

S. de la Red Arroyo, R. Osés Primo, R. Molinero Pinilla, C. González Anguren, and A. Parra Osés

Subjects
Medicine(all), business.industry, General Medicine, Primary care, Atencion primaria, Minor surgery, Malignant lesions, Atención primaria, Cirugía menor, Medicine, Lesiones malignas, business, Family Practice, Humanities
Abstract

ObjetivoDescribir las características de las lesiones malignas y premalignas detectadas en las intervenciones de cirugía menor realizadas en un centro de saludDiseñoEstudio descriptivo retrospectivoParticipantesSe analizaron 682 lesiones correspondientes a todas las lesiones extirpadas remitidas a anatomía patológica, exceptuando los quistes epidérmicos y triquilemales, lipomas, molluscum, verrugas vulgares y uñasEmplazamientoCentro de Salud Rochapea (Pamplona)Mediciones principalesAnalizamos los diagnósticos anatomopatológicos y la distribución por sexos, grupos de edad, localización, técnica y afección de bordes en 27 lesiones displásicas y 11 lesiones malignasResultadosEncontramos una mayor frecuencia de lesiones malignas y premalignas en mujeres, entre 15 y 44 años de edad para las displasias y entre 45 y 64 años para las malignas. La localización más frecuente fue la espalda, y la técnica más empleada la escisión fusiforme. Con esta técnica encontramos el mayor porcentaje de bordes sin lesión en las displasias. Las lesiones que tenían afectados los bordes corresponden a muestras de punch y escisión circular. Ninguna de las lesiones malignas presentaba afección de bordesConclusionesLa mayor parte de las lesions malignas no se sospechan, aparecen en muestras que se remiten con un diagnóstico de benignidad. El empleo de ciertas técnicas como la escisión fusiforme en las lesiones en que existe una potencial malignidad, aunque en principio parezcan benignas, nos permite una extirpación con bordes libresObjectiveTo describe the characteristics of the malignant and pre-malignant lesions found in the minor surgical interventions performed at a health centreDesignRetrospective, descriptive studyParticipants682 lesions: all the lesions extirpated and referred to pathology except for epidermal and trichilemmal cysts, lipomas, molluscum, common warts, and nailsSettingRochapea Health Centre, PamplonaMain measurementsWe analysed the anatomical-pathological results and the distribution by sex, age-group, location, technique and edges affected in 27 dysplasias and 11 malignant lesionsResultsWe found that malignant and premalignant lesions were more common in women, aged 15 to 44 for dysplasias and 45- 64 for malignant lesions. The most common location was on the back; the most frequent technique, fusiform excision. This technique had the highest percentage of edges without lesion in dysplasias. The lesions whose edges were affected corresponded to punch and circular excision samples. None of the malignant lesions had their edges affectedConclusionsMost malignant lesions are not suspected. They appear in samples referred with a diagnosis of benign. Employment of techniques such as fusiform excision in lesions which are potentially malign, even though in principle they seem benign, enables them to be extirpated with free edges

Published
2003
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11. La siniestralidad laboral en la población inmigrante de Navarra en el 2006. Una aproximación a sus causas

Author

Jesús Fernández Baraibar, José Ramón Ayestarán Ruiz Bazán, Ángel Parra Osés, and Vega García López

Subjects
lcsh:Internal medicine, Casual, media_common.quotation_subject, Immigration, Siniestralidad, Characteristics and causes, lcsh:Medicine, characteristics and causes, immigrants workers, Politics, lcsh:RC963-969, Occupational injuries, Medicine, lcsh:RC31-1245, media_common, business.industry, Población trabajadora inmigrante, Social change, lcsh:R, Immigrants workers, Spanish Civil War, Agriculture, lcsh:Industrial medicine. Industrial hygiene, Demographic economics, Working group, business, Seriousness
Abstract

Introducción: El cambio económico y social que está experimentando Navarra en las últimas décadas está asociado con la llegada de un flujo creciente de inmigrantes. El fenómeno migratorio plantea un gran número de desafíos: legislativos, políticos, culturales, sociales, sanitarios y por supuesto laborales. Desde el punto de vista laboral la incorporación de inmigrantes al mercado de trabajo ha supuesto, sin duda, aspectos positivos, pero también algunas disfunciones y problemas, siendo uno de ellos los altos niveles de siniestralidad que presenta este colectivo. Objetivos: Analizar y profundizar en las características y causas de la siniestralidad en este colectivo y los factores que podrían incidir en ella. Metodología: Estudio descriptivo - observacional tomando como base los datos del Registro de Accidentes de Trabajo del año 2006. Resultados: Para un 9,8% de trabajadores extranjeros, éstos sufren el 20% de los accidentes de trabajo( AT). Las mujeres extranjeras se accidentan casi 4 puntos menos en porcentaje relativo que las nacionales. La distribución de AT es similar en ambas poblaciones atendiendo a su gravedad, los trabajadores extranjeros sufrieron el 19,3% de los accidentes graves y el 15,8% de los mortales. En este colectivo los grupos de edades más jóvenes presentan porcentajes más elevados de siniestralidad. Por sectores económicos: una tercera parte de los accidentes en Agricultura y Construcción corresponden a trabajadores emigrantes. Su distribución porcentual es reflejo de la diferente ocupación sectorial de este colectivo, duplicando los porcentajes en los sectores agrícola y construcción en comparación con la población de acogida. En población extranjera la proporción de hombres que se accidentan es superior al de las mujeres en todos los sectores productivos, excepto en Servicios. Cerca de 80% de accidentes en población inmigrante acontece en puestos de baja cualificación o no cualificados y casi las tres cuartas partes de los sucesos se producen en trabajadores inmigrantes con menos de un año de antigüedad en el puesto. La forma de producción, descripción y localización de las lesiones y el agente material responsable presentan perfiles de distribución superponibles en ambos colectivos. En porcentaje relativo los accidentes de trabajo notificados por Empresas de Trabajo Temporal en inmigrantes superan a los comunicados en población autóctona y mientras que casi el 75% se dan en varones, una tercera parte corresponden a población trabajadora extranjera. Además mientras el peso relativo de los ocurridos en mujeres extranjeras con esta modalidad de contrato supera al de nativas, en varones ocurre al contrario. Los índices de incidencia de AT por sector de actividad son superiores en el colectivo extranjero frente a los índices en población total, incluso en aquellas actividades menos representadas. En población inmigrante tanto los índices de incidencia globales como los diferentes índices según gravedad se duplican con respecto a la población nacional. Estos índices son inferiores en los países UE en relación al resto de países no UE. Por zonas geográficas de origen superan el índice medio los trabajadores del Magreb, Europa Occidental y África y por países Marruecos, Argelia y Portugal. Conclusiones y discusión: Tal vez las condiciones de trabajo que se caracterizan por la excesiva temporalidad, la frecuente subcontratación, el elevado índice de rotación (casi las tres cuartas partes de los accidentados extranjeros llevaban menos de un año en el puesto de trabajo) hacen que proporcionalmente el número de extranjeros con escasa experiencia y falta de adaptación sea todavía mayor que en el conjunto de la población. Es posible que la inestabilidad y precariedad laboral que afectan al colectivo inmigrante pudieran influir en su mayor incidencia. Otros trabajos a nivel nacional e internacional confirman tal aumento en los índices de incidencia. Analizar si este exceso de accidentalidad se debe a factores ocupacionales, tareas de mayor riesgo o bien es debida a factores de índole cultural, idiomática o adaptativos (tiempo de permanencia en nuestro país) son factores que se abordan en la discusión.Introducction: The economical and social changes Navarra is suffering during the last decades, is connected with the increasing immigration income rates. This aspect supposes different and huge legal, political, cultural, social, sanitary and of course professional challenges. Professionally speaking the big immigration income rates have, of course, advantages but have also some problems and dysfunctions as the very high accident levels this collective is suffering. Objetives: Analyzing and widening the accident’s characteristics and reasons and studying the possible causes Methodology: Descriptive and observation study by analyzing the Working Accident Register Year 2006. Results: At the moment a 9,8% of the total workers are foreign workers. These foreign workers have a 20% of the total working accident rate (WAR). Foreign working women have 4% less of the WAR than the local working women .If we talk about the seriousness of the accidents; the WAR average is similar between the foreign and the local workers. Foreign workers suffer the 19,3% of the grave accidents and 15,8% of the fatal ones. The under-aged working groups have a higher % of working accidents. If we study the different economical sectors, the results are the following: One-third of the accidents occurred in the Agriculture and Construction sector are suffered by immigrant workers. The reason is that immigrant workers cover a very wide range of sectors, being double as local workers in these both mentioned sectors. Immigrant men workers accident rate is higher than the immigrant women workers accident rate in all the sectors, except the non-productive industries. Almost the 80% of the working accidents suffered by the immigrant population occurred in the low level or not level qualification jobs and almost three quarters of the casualties are less than one year experimented workers. The accident’s happenings are, for both profiles, similar. The relative percent of the working accidents disclosed by the Casual Job Search Companies is higher for the immigrant population as for the local one. Almost the 75% is suffered by men workers and one-third by foreign workers. The relative percent of the working accidents disclosed by the Casual Job Search Companies is also higher for the foreign working women but lower for foreign working men. The incidence rate classified by activity sector is always higher for the foreign collective, even the less represented activity sectors. The immigrant population’s accident rate is double not only for the global rate but also for all the other rates classified by seriousness. These rates are lower for the EU countries as for the NO-EU countries. The highest rates are found in the following areas: Maghreb, Occidental Europe and Africa. The countries classification is the following: Morocco, Algeria and Portugal. Conclusion and discussions: Perhaps the too temporal working conditions or the too frequent subcontracting working conditions or the too frequent rotary conditions connote a higher rate of non-experience or non-adapted immigrant workers. Perhaps this inconstancy or this predicament acts on the working accident rate. Other national and international works corroborate the accident rate increase. The search of the accident rate’s source: working or risk factors or cultural, idiomatic or adaption factors will be under discussion.

Published
2008

12. [Pre-malignant and malignant lesions in minor surgery at a health centre. Appearances can't be trusted]

Author

C, González Anguren, R, Osés Primo, R, Molinero Pinilla, A, Parra Osés, and S, de la Red Arroyo

Subjects
Adult, Male, Skin Neoplasms, Adolescent, Middle Aged, Originales, Humans, Female, Health Facilities, Minor Surgical Procedures, Nevus, Precancerous Conditions, Aged, Retrospective Studies, Skin
Abstract

OBJECTIVE: To describe the characteristics of the malignant and pre-malignant lesions found in the minor surgical interventions performed at a health centre DESIGN: Retrospective, descriptive study PARTICIPANTS: 682 lesions: all the lesions extirpated and referred to pathology except for epidermal and trichilemmal cysts, lipomas, molluscum, common warts, and nails SETTING: Rochapea Health Centre, Pamplona MAIN MEASUREMENTS: We analysed the anatomical-pathological results and the distribution by sex, age-group, location, technique and edges affected in 27 dysplasias and 11 malignant lesions RESULTS: We found that malignant and premalignant lesions were more common in women, aged 15 to 44 for dysplasias and 45- 64 for malignant lesions. The most common location was on the back; the most frequent technique, fusiform excision. This technique had the highest percentage of edges without lesion in dysplasias. The lesions whose edges were affected corresponded to punch and circular excision samples. None of the malignant lesions had their edges affected CONCLUSIONS: Most malignant lesions are not suspected. They appear in samples referred with a diagnosis of benign. Employment of techniques such as fusiform excision in lesions which are potentially malign, even though in principle they seem benign, enables them to be extirpated with free edges

Published
2003

16. [Management of viral dermatologic lesions primary care].

Author

Artieda Lanas M, Miranda Alcoz S, Martín-Almendros S, Parra Osés A, Alvarez Martín A, and Sobrado Rojo R

Subjects
Adolescent, Adult, Condylomata Acuminata therapy, Female, Humans, Male, Middle Aged, Retrospective Studies, Molluscum Contagiosum therapy, Warts therapy
Abstract

Objective: To describe the characteristics of various viral tumoural lesions and their treatment by family doctors., Design: Descriptive, retrospective study., Setting: Urban health centre., Patients: 225 patients registered at the centre., Interventions: The following variables were collected over two years: sex, age, type of lesion, anatomical location and treatments used., Measurements and Main Results: 51% of the sample were men, and 49% women. Almost half were between 15 and 34. The most common pathologies were common verrucas (72%), plantar warts (19%) and Molluscum contagiosum (8%). All the plantar warts were located on the lower limbs; condylomas and bowenoid papulosis on the genitals; 35% of the common verrucas on the head and neck (the rest on upper limbs); and 26% of the Molluscum contagiosum on the head and neck too (37% on the thorax and/or abdomen). All the genital lesions were treated medically. Cryotherapy was the most common treatment, used for all plantar warts, 53% of verrucas and 21% of the Molluscum contagiosum. Curettage was used on 80% of the Molluscum and 30% of the verrucas. 11% of the verrucas were sliced off., Conclusions: There are no conclusive data in the literature about the choice of technique for treating these lesions. We recommend cryotherapy for multiple lesions and in areas where surgery could have functional repercussions. Curettage seems effective for Molluscum contagiosum and where there is resistance to medical treatment.

Published
2001
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