310 results on '"Pan W.-H."'
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2. Optimal Design of Funicular Arches Under Equally Spaced Point Loads for Maximum Buckling Load.
- Author
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Wang, C. M., Pan, W. H., Zhang, Y. P., and Hao, Y. Z.
- Subjects
- *
ARCHES , *BENDING moment , *STRUCTURAL models , *DECISION making - Abstract
This paper presents the optimal designs of pinned supported funicular arches under equally spaced point loads for maximum in-plane buckling load. Under such loading conditions, the funicular arch shapes comprise straight arch members between the point loads, that is, following the shape of the bending moment diagram of an equivalent simply supported beam under the same loading condition. Two classes of funicular arch optimization problems are considered herein. The first class of funicular arches imposes a constraint on the cross-sectional area to be uniform throughout the entire arch length. The second class of funicular arches allows the cross-sectional area to be different from one straight arch member to another member. To facilitate the buckling analysis, the Hencky bar-chain model (HBM) is adopted. This discrete structural model simplifies the optimization process as the decision variables are the HBM rotational spring stiffnesses that define the cross-sectional areas and the horizontal force that controls the arch shape. Presented herein are new optimal funicular arch shapes under various numbers of equally spaced point loads. By increasing the number of point loads, the optimal solution approaches the solution of a parabolic arch under a uniformly distributed load. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. Rapid adiposity growth increases risks of new-onset asthma and airway inflammation in children
- Author
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Chen, Y-C, Chih, A-H, Chen, J-R, Liou, T-H, Pan, W-H, and Lee, Y L
- Published
- 2017
- Full Text
- View/download PDF
4. Aetiology of tinea capitis in China: a multicentre prospective study
- Author
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Chen, X.-Q., primary, Zheng, D.-Y., additional, Xiao, Y.-Y., additional, Dong, B.-L., additional, Cao, C.-W., additional, Ma, L., additional, Tong, Z.-S., additional, Zhu, M., additional, Liu, Z.-H., additional, Xi, L.-Y., additional, Fu, M., additional, Jin, Y., additional, Yin, B., additional, Li, F.-Q., additional, Li, X.-F., additional, Abliz, P., additional, Liu, H.-F., additional, Zhang, Y., additional, Yu, N., additional, Wu, W.-W., additional, Xiong, X.-C., additional, Zeng, J.-S., additional, Huang, H.-Q., additional, Jiang, Y.-P., additional, Chen, G.-Z., additional, Pan, W.-H., additional, Sang, H., additional, Wang, Y., additional, Guo, Y., additional, Shi, D.-M., additional, Yang, J.-X., additional, Chen, W., additional, Wan, Z., additional, Li, R.-Y., additional, Wang, A.-P., additional, Ran, Y.-P., additional, and Yu, J., additional
- Published
- 2022
- Full Text
- View/download PDF
5. Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
- Author
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Iurilli, M.L.C. Zhou, B. Bennett, J.E. Carrillo-Larco, R.M. Sophiea, M.K. Rodriguez-Martinez, A. Bixby, H. Solomon, B.D. Taddei, C. Danaei, G. Di Cesare, M. Stevens, G.A. Riley, L.M. Savin, S. Cowan, M.J. Bovet, P. Damasceno, A. Chirita-Emandi, A. Hayes, A.J. Ikeda, N. Jackson, R.T. Khang, Y.-H. Laxmaiah, A. Liu, J. Miranda, J.J. Saidi, O. Sebert, S. Sorić, M. Starc, G. Gregg, E.W. Abarca-Gómez, L. Abdeen, Z.A. Abdrakhmanova, S. Ghaffar, S.A. Rahim, H.F.A. Abu-Rmeileh, N.M. Garba, J.A. Acosta-Cazares, B. Adams, R.J. Aekplakorn, W. Afsana, K. Afzal, S. Agdeppa, I.A. Aghazadeh-Attari, J. Aguilar-Salinas, C.A. Agyemang, C. Ahmad, M.H. Ahmad, N.A. Ahmadi, A. Ahmadi, N. Ahmed, S.H. Ahrens, W. Aitmurzaeva, G. Ajlouni, K. Al-Hazzaa, H.M. Al-Lahou, B. Al-Raddadi, R. Alarouj, M. AlBuhairan, F. AlDhukair, S. Ali, M.M. Alkandari, A. Alkerwi, A. Allin, K. Alvarez-Pedrerol, M. Aly, E. Amarapurkar, D.N. Amiri, P. Amougou, N. Amouyel, P. Andersen, L.B. Anderssen, S.A. Ängquist, L. Anjana, R.M. Ansari-Moghaddam, A. Aounallah-Skhiri, H. Araújo, J. Ariansen, I. Aris, T. Arku, R.E. Arlappa, N. Aryal, K.K. Aspelund, T. Assah, F.K. Assunção, M.C.F. Aung, M.S. Auvinen, J. Mária Avdicová Avi, S. Azevedo, A. Azimi-Nezhad, M. Azizi, F. Azmin, M. Babu, B.V. Bæksgaard Jørgensen, M. Baharudin, A. Bahijri, S. Baker, J.L. Balakrishna, N. Bamoshmoosh, M. Banach, M. Bandosz, P. Banegas, J.R. Baran, J. Barbagallo, C.M. Barceló, A. Barkat, A. Barros, A.J.D. Barros, M.V.G. Basit, A. Bastos, J.L.D. Bata, I. Batieha, A.M. Batista, R.L. Battakova, Z. Batyrbek, A. Baur, L.A. Beaglehole, R. Bel-Serrat, S. Belavendra, A. Romdhane, H.B. Benedics, J. Benet, M. Bergh, I.H. Berkinbayev, S. Bernabe-Ortiz, A. Bernotiene, G. Bettiol, H. Bezerra, J. Bhagyalaxmi, A. Bharadwaj, S. Bhargava, S.K. Bhutta, Z.A. Bi, H. Bi, Y. Bia, D. Lele, E.C.B. Bikbov, M.M. Bista, B. Bjelica, D.J. Bjerregaard, P. Bjertness, E. Bjertness, M.B. Björkelund, C. Bloch, K.V. Blokstra, A. Bo, S. Bobak, M. Boddy, L.M. Boehm, B.O. Boeing, H. Boggia, J.G. Bogova, E. Boissonnet, C.P. Bojesen, S.E. Bonaccio, M. Bongard, V. Bonilla-Vargas, A. Bopp, M. Borghs, H. Braeckevelt, L. Braeckman, L. Bragt, M.C.E. Brajkovich, I. Branca, F. Breckenkamp, J. Breda, J. Brenner, H. Brewster, L.M. Brian, G.R. Brinduse, L. Brophy, S. Bruno, G. Bueno-de-Mesquita, H.B. Bugge, A. Buoncristiano, M. Burazeri, G. Burns, C. de León, A.C. Cacciottolo, J. Cai, H. Cama, T. Cameron, C. Camolas, J. Can, G. Candido, A.P.C. Cañete, F. Capanzana, M.V. Capková, N. Capuano, E. Capuano, V. Cardol, M. Cardoso, V.C. Carlsson, A.C. Carmuega, E. Carvalho, J. Casajús, J.A. Casanueva, F.F. Celikcan, E. Censi, L. Cervantes-Loaiza, M. Cesar, J.A. Chamukuttan, S. Chan, A.W. Chan, Q. Chaturvedi, H.K. Chaturvedi, N. Rahim, N.C.A. Chee, M.L. Chen, C.-J. Chen, F. Chen, H. Chen, S. Chen, Z. Cheng, C.-Y. Cheraghian, B. Chetrit, A. Chikova-Iscener, E. Chiolero, A. Chiou, S.-T. Chirlaque, M.-D. Cho, B. Christensen, K. Christofaro, D.G. Chudek, J. Cifkova, R. Cilia, M. Cinteza, E. Claessens, F. Clarke, J. Clays, E. Cohen, E. Concin, H. Confortin, S.C. Cooper, C. Coppinger, T.C. Corpeleijn, E. Costanzo, S. Cottel, D. Cowell, C. Craig, C.L. Crampin, A.C. Crujeiras, A.B. Csilla, S. Cucu, A.M. Cui, L. Cureau, F.V. Czenczek-Lewandowska, E. D’Arrigo, G. d’Orsi, E. Dacica, L. Dal Re Saavedra, M.A. Dallongeville, J. Damsgaard, C.T. Dankner, R. Dantoft, T.M. Dasgupta, P. Dastgiri, S. Dauchet, L. Davletov, K. De Backer, G. De Bacquer, D. de Gaetano, G. De Henauw, S. de Oliveira, P.D. De Ridder, D. De Ridder, K. de Rooij, S.R. De Smedt, D. Deepa, M. Deev, A.D. DeGennaro, V., Jr Dehghan, A. Delisle, H. Delpeuch, F. Demarest, S. Dennison, E. Dereń, K. Deschamps, V. Dhimal, M. Di Castelnuovo, A.F. Dias-da-Costa, J.S. Díaz-Sánchez, M.E. Diaz, A. Dika, Z. Djalalinia, S. Djordjic, V. Do, H.T.P. Dobson, A.J. Donati, M.B. Donfrancesco, C. Donoso, S.P. Döring, A. Dorobantu, M. Dorosty, A.R. Doua, K. Dragano, N. Drygas, W. Duan, J.L. Duante, C.A. Duboz, P. Duda, R.B. Duleva, V. Dulskiene, V. Dumith, S.C. Dushpanova, A. Dzerve, V. Dziankowska-Zaborszczyk, E. Eddie, R. Eftekhar, E. Egbagbe, E.E. Eggertsen, R. Eghtesad, S. Eiben, G. Ekelund, U. El-Khateeb, M. Ati, J.E. Eldemire-Shearer, D. Eliasen, M. Elliott, P. Engle-Stone, R. Enguerran, M. Erasmus, R.T. Erbel, R. Erem, C. Eriksen, L. Eriksson, J.G. Escobedo-de la Peña, J. Eslami, S. Esmaeili, A. Evans, A. Faeh, D. Fakhretdinova, A.A. Fall, C.H. Faramarzi, E. Farjam, M. Sant’Angelo, V.F. Farzadfar, F. Fattahi, M.R. Fawwad, A. Felix-Redondo, F.J. Ferguson, T.S. Fernandes, R.A. Fernández-Bergés, D. Ferrante, D. Ferrao, T. Ferrari, M. Ferrario, M.M. Ferreccio, C. Ferrer, E. Ferrieres, J. Figueiró, T.H. Fijalkowska, A. Fink, G. Fischer, K. Foo, L.H. Forsner, M. Fouad, H.M. Francis, D.K. Maria do Carmo Franco Frikke-Schmidt, R. Frontera, G. Fuchs, F.D. Fuchs, S.C. Fujiati, I.I. Fujita, Y. Fumihiko, M. Furusawa, T. Gaciong, Z. Gafencu, M. Galbarczyk, A. Galenkamp, H. Galeone, D. Galfo, M. Galvano, F. Gao, J. Garcia-de-la-Hera, M. García-Solano, M. Gareta, D. Garnett, S.P. Gaspoz, J.-M. Gasull, M. Gaya, A.C.A. Gaya, A.R. Gazzinelli, A. Gehring, U. Geiger, H. Geleijnse, J.M. Ghanbari, A. Ghasemi, E. Gheorghe-Fronea, O.-F. Giampaoli, S. Gianfagna, F. Gill, T.K. Giovannelli, J. Gironella, G. Giwercman, A. Gkiouras, K. Godos, J. Gogen, S. Goldberg, M. Goldsmith, R.A. Goltzman, D. Gómez, S.F. Gomula, A. da Silva, B.G.C. Gonçalves, H. Gonzalez-Chica, D.A. Gonzalez-Gross, M. González-Leon, M. González-Rivas, J.P. González-Villalpando, C. González-Villalpando, M.-E. Gonzalez, A.R. Gottrand, F. Graça, A.P. Graff-Iversen, S. Grafnetter, D. Grajda, A. Grammatikopoulou, M.G. Gregor, R.D. Grodzicki, T. Grøholt, E.K. Grøntved, A. Grosso, G. Gruden, G. Gu, D. Gualdi-Russo, E. Guallar-Castillón, P. Gualtieri, A. Gudmundsson, E.F. Gudnason, V. Guerrero, R. Guessous, I. Guimaraes, A.L. Gulliford, M.C. Gunnlaugsdottir, J. Gunter, M.J. Guo, X.-H. Guo, Y. Gupta, P.C. Gupta, R. Gureje, O. Gurzkowska, B. Gutiérrez-González, E. Gutierrez, L. Gutzwiller, F. Ha, S. Hadaegh, F. Hadjigeorgiou, C.A. Haghshenas, R. Hakimi, H. Halkjær, J. Hambleton, I.R. Hamzeh, B. Hange, D. Hanif, A.A.M. Hantunen, S. Hao, J. Kumar, R.H. Hashemi-Shahri, S.M. Hassapidou, M. Hata, J. Haugsgjerd, T. He, J. He, Y. He, Y. Heidinger-Felso, R. Heinen, M. Hejgaard, T. Hendriks, M.E. dos Santos Henrique, R. Henriques, A. Cadena, L.H. Herrala, S. Herrera, V.M. Herter-Aeberli, I. Heshmat, R. Hill, A.G. Ho, S.Y. Ho, S.C. Hobbs, M. Holdsworth, M. Homayounfar, R. Homs, C. Hopman, W.M. Horimoto, A.R.V.R. Hormiga, C.M. Horta, B.L. Houti, L. Howitt, C. Htay, T.T. Htet, A.S. Htike, M.M.T. Hu, Y. Huerta, J.M. Huhtaniemi, I.T. Huiart, L. Petrescu, C.H. Huisman, M. Husseini, A. Huu, C.N. Huybrechts, I. Hwalla, N. Hyska, J. Iacoviello, L. Ibarluzea, J.M. Ibrahim, M.M. Wong, N.I. Ikram, M.A. Iotova, V. Irazola, V.E. Ishida, T. Islam, M. Islam, S.M.S. Iwasaki, M. Jacobs, J.M. Jaddou, H.Y. Jafar, T. James, K. Jamil, K.M. Jamrozik, K. Janszky, I. Janus, E. Jarani, J. Jarvelin, M.-R. Jasienska, G. Jelakovic, A. Jelakovic, B. Jennings, G. Jha, A.K. Jiang, C.Q. Jimenez, R.O. Jöckel, K.-H. Joffres, M. Johansson, M. Jokelainen, J.J. Jonas, J.B. Jonnagaddala, J. Jørgensen, T. Joshi, P. Joukar, F. Jovic, D.P. Jóźwiak, J.J. Juolevi, A. Jurak, G. Simina, I.J. Juresa, V. Kaaks, R. Kaducu, F.O. Kafatos, A. Kajantie, E.O. Kalmatayeva, Z. Kalter-Leibovici, O. Kameli, Y. Kampmann, F.B. Kanala, K.R. Kannan, S. Kapantais, E. Karakosta, A. Kårhus, L.L. Karki, K.B. Katibeh, M. Katz, J. Katzmarzyk, P.T. Kauhanen, J. Kaur, P. Kavousi, M. Kazakbaeva, G.M. Keil, U. Boker, L.K. Keinänen-Kiukaanniemi, S. Kelishadi, R. Kelleher, C. Kemper, H.C.G. Kengne, A.P. Keramati, M. Kerimkulova, A. Kersting, M. Key, T. Khader, Y.S. Khalili, D. Khaw, K.-T. Kheiri, B. Kheradmand, M. Khosravi, A. Khouw, I.M.S.L. Kiechl-Kohlendorfer, U. Kiechl, S. Killewo, J. Kim, D.W. Kim, H.C. Kim, J. Kindblom, J.M. Klakk, H. Klimek, M. Klimont, J. Klumbiene, J. Knoflach, M. Koirala, B. Kolle, E. Kolsteren, P. König, J. Korpelainen, R. Korrovits, P. Korzycka, M. Kos, J. Koskinen, S. Kouda, K. Kovacs, V.A. Kowlessur, S. Koziel, S. Kratenova, J. Kratzer, W. Kriemler, S. Kristensen, P.L. Krokstad, S. Kromhout, D. Kruger, H.S. Kubinova, R. Kuciene, R. Kujala, U.M. Kujundzic, E. Kulaga, Z. Kumar, R.K. Kunešová, M. Kurjata, P. Kusuma, Y.S. Kuulasmaa, K. Kyobutungi, C. La, Q.N. Laamiri, F.Z. Laatikainen, T. Lachat, C. Laid, Y. Lam, T.H. Lambrinou, C.-P. Landais, E. Lanska, V. Lappas, G. Larijani, B. Latt, T.S. Lauria, L. Lazo-Porras, M. Le Coroller, G. Bao, K.L.N. Le Port, A. Le, T.D. Lee, J. Lee, J. Lee, P.H. Lehmann, N. Lehtimäki, T. Lemogoum, D. Levitt, N.S. Li, Y. Liivak, M. Lilly, C.L. Lim, W.-Y. Lima-Costa, M.F. Lin, H.-H. Lin, X. Lin, Y.-T. Lind, L. Linneberg, A. Lissner, L. Litwin, M. Liu, L. Lo, W.-C. Loit, H.-M. Long, K.Q. Lopes, L. Lopes, O. Lopez-Garcia, E. Lopez, T. Lotufo, P.A. Lozano, J.E. Lukrafka, J.L. Luksiene, D. Lundqvist, A. Lundqvist, R. Lunet, N. Lunogelo, C. Lustigová, M. Łuszczki, E. Ma, G. Ma, J. Ma, X. Machado-Coelho, G.L.L. Machado-Rodrigues, A.M. Macieira, L.M. Madar, A.A. Maggi, S. Magliano, D.J. Magnacca, S. Magriplis, E. Mahasampath, G. Maire, B. Majer, M. Makdisse, M. Mäki, P. Malekzadeh, F. Malekzadeh, R. Malhotra, R. Rao, K.M. Malyutina, S.K. Maniego, L.V. Manios, Y. Mann, J.I. Mansour-Ghanaei, F. Manzato, E. Margozzini, P. Markaki, A. Markey, O. Ioannidou, E.M. Marques-Vidal, P. Marques, L.P. Marrugat, J. Martin-Prevel, Y. Martin, R. Martorell, R. Martos, E. Maruszczak, K. Marventano, S. Mascarenhas, L.P. Masoodi, S.R. Mathiesen, E.B. Mathur, P. Matijasevich, A. Matsha, T.E. Mavrogianni, C. Mazur, A. Mbanya, J.C.N. McFarlane, S.R. McGarvey, S.T. McKee, M. McLachlan, S. McLean, R.M. McLean, S.B. McNulty, B.A. Benchekor, S.M. Medzioniene, J. Mehdipour, P. Mehlig, K. Mehrparvar, A.H. Meirhaeghe, A. Meisfjord, J. Meisinger, C. Menezes, A.M.B. Menon, G.R. Mensink, G.B.M. Menzano, M.T. Mereke, A. Meshram, I.I. Metspalu, A. Meyer, H.E. Mi, J. Michaelsen, K.F. Michels, N. Mikkel, K. Milkowska, K. Miller, J.C. Minderico, C.S. Mini, G.K. Miquel, J.F. Mirjalili, M.R. Mirkopoulou, D. Mirrakhimov, E. Mišigoj-Durakovic, M. Mistretta, A. Mocanu, V. Modesti, P.A. Moghaddam, S.S. Mohajer, B. Mohamed, M.K. Mohamed, S.F. Mohammad, K. Mohammadi, Z. Mohammadifard, N. Mohammadpourhodki, R. Mohan, V. Mohanna, S. Yusoff, M.F.M. Mohebbi, I. Mohebi, F. Moitry, M. Molbo, D. Møllehave, L.T. Møller, N.C. Molnár, D. Momenan, A. Mondo, C.K. Monroy-Valle, M. Monterrubio-Flores, E. Monyeki, K.D.K. Moon, J.S. Moosazadeh, M. Moreira, L.B. Morejon, A. Moreno, L.A. Morgan, K. Morin, S.N. Mortensen, E.L. Moschonis, G. Mossakowska, M. Mostafa, A. Mota-Pinto, A. Mota, J. Motlagh, M.E. Motta, J. Moura-dos-Santos, M.A. Mridha, M.K. Msyamboza, K.P. Mu, T.T. Muc, M. Mugoša, B. Muiesan, M.L. Mukhtorova, P. Müller-Nurasyid, M. Murphy, N. Mursu, J. Murtagh, E.M. Musa, K.I. Milanovic, S.M. Musil, V. Mustafa, N. Nabipour, I. Naderimagham, S. Nagel, G. Naidu, B.M. Najafi, F. Nakamura, H. Námešná, J. Nang, E.E.K. Nangia, V.B. Nankap, M. Narake, S. Nardone, P. Nauck, M. Neal, W.A. Nejatizadeh, A. Nekkantti, C. Nelis, K. Nelis, L. Nenko, I. Neovius, M. Nervi, F. Nguyen, C.T. Nguyen, N.D. Nguyen, Q.N. Nieto-Martínez, R.E. Nikitin, Y.P. Ning, G. Ninomiya, T. Nishtar, S. Noale, M. Noboa, O.A. Nogueira, H. Norat, T. Nordendahl, M. Nordestgaard, B.G. Noto, D. Nowak-Szczepanska, N. Al Nsour, M. Nuhoglu, I. Nurk, E. O’Neill, T.W. O’Reilly, D. Obreja, G. Ochimana, C. Ochoa-Avilés, A.M. Oda, E. Oh, K. Ohara, K. Ohlsson, C. Ohtsuka, R. Olafsson, O. Olinto, M.T.A. Oliveira, I.O. Omar, M.A. Onat, A. Ong, S.K. Ono, L.M. Ordunez, P. Ornelas, R. Ortiz, A.P. Ortiz, P.J. Osler, M. Osmond, C. Ostojic, S.M. Ostovar, A. Otero, J.A. Overvad, K. Owusu-Dabo, E. Paccaud, F.M. Padez, C. Pagkalos, I. Pahomova, E. de Paiva, K.M. Pajak, A. Palli, D. Palloni, A. Palmieri, L. Pan, W.-H. Panda-Jonas, S. Pandey, A. Panza, F. Papandreou, D. Park, S.-W. Park, S. Parnell, W.R. Parsaeian, M. Pascanu, I.M. Pasquet, P. Patel, N.D. Pecin, I. Pednekar, M.S. Peer, N. Pei, G. Peixoto, S.V. Peltonen, M. Pereira, A.C. Peres, M.A. Pérez-Farinós, N. Pérez, C.M. Peterkova, V. Peters, A. Petersmann, A. Petkeviciene, J. Petrauskiene, A. Pettenuzzo, E. Peykari, N. Pham, S.T. Pichardo, R.N. Pierannunzio, D. Pigeot, I. Pikhart, H. Pilav, A. Pilotto, L. Pistelli, F. Pitakaka, F. Piwonska, A. Pizarro, A.N. Plans-Rubió, P. Poh, B.K. Pohlabeln, H. Pop, R.M. Popovic, S.R. Porta, M. Posch, G. Poudyal, A. Poulimeneas, D. Pouraram, H. Pourfarzi, F. Pourshams, A. Poustchi, H. Pradeepa, R. Price, A.J. Price, J.F. Providencia, R. Puder, J.J. Pudule, I. Puhakka, S.E. Puiu, M. Punab, M. Qasrawi, R.F. Qorbani, M. Bao, T.Q. Radic, I. Radisauskas, R. Rahimikazerooni, S. Rahman, M. Rahman, M. Raitakari, O. Raj, M. Rakhimova, E. Rakhmatulloev, S. Rakovac, I. Rao, S.R. Ramachandran, A. Ramke, J. Ramos, E. Ramos, R. Rampal, L. Rampal, S. Rarra, V. Rascon-Pacheco, R.A. Rasmussen, M. Rech, C.R. Redon, J. Reganit, P.F.M. Regecová, V. Revilla, L. Rezaianzadeh, A. Ribas-Barba, L. Ribeiro, R. Riboli, E. Richter, A. Rigo, F. Rinaldo, N. de Wit, T.F.R. Rito, A. Ritti-Dias, R.M. Rivera, J.A. Robitaille, C. Roccaldo, R. Rodrigues, D. Rodríguez-Artalejo, F. del Cristo Rodriguez-Perez, M. Rodríguez-Villamizar, L.A. Roggenbuck, U. Rojas-Martinez, R. Rojroongwasinkul, N. Romaguera, D. Romeo, E.L. Rosario, R.V. Rosengren, A. Rouse, I. Roy, J.G.R. Rubinstein, A. Rühli, F.J. Ruidavets, J.-B. Ruiz-Betancourt, B.S. Ruiz-Castell, M. Moreno, E.R. Rusakova, I.A. Jonsson, K.R. Russo, P. Rust, P. Rutkowski, M. Sabanayagam, C. Sacchini, E. Sachdev, H.S. Sadjadi, A. Safarpour, A.R. Safiri, S. Saki, N. Salanave, B. Martinez, E.S. Salmerón, D. Salomaa, V. Salonen, J.T. Salvetti, M. Samoutian, M. Sánchez-Abanto, J. Sans, S. Marina, L.S. Santos, D.A. Santos, I.S. Santos, L.C. Santos, M.P. Santos, O. Santos, R. 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Zargar, A.H. Zaw, K.K. Zdrojewski, T. Zejglicova, K. Vrkic, T.Z. Zeng, Y. Zhang, L. Zhang, Z.-Y. Zhao, D. Zhao, M.-H. Zhao, W. Zhen, S. Zheng, W. Zheng, Y. Zholdin, B. Zhou, M. Zhu, D. Zins, M. Zitt, E. Zocalo, Y. Cisneros, J.Z. Zuziak, M. Ezzati, M. Filippi, S. NCD Risk Factor Collaboration (NCD-RisC)
- Subjects
nutritional and metabolic diseases ,sense organs ,skin and connective tissue diseases - Abstract
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions. © Copyright.
- Published
- 2021
6. Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
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- Published
- 2021
7. Association between folate status, diabetes, antihypertensive medication and age-related cataracts in elderly Taiwanese
- Author
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Chen, Kuan-Ju, Pan, W. -H., Huang, C. -J., and Lin, Bi-Fong
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- 2011
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8. A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor
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Chung, C-M, Wang, R-Y, Chen, J-W, Fann, C S J, Leu, H-B, Ho, H-Y, Ting, C-T, Lin, T-H, Sheu, S-H, Tsai, W-C, Chen, J-H, Jong, Y-S, Lin, S-J, Chen, Y-T, and Pan, W-H
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- 2010
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9. Repositioning of the global epicentre of non-optimal cholesterol
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Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. (Julia), Tsugane, S. (Shoichiro), Tulloch-Reid, M.K. (Marshall K.), Tuomainen, T.-P. (Tomi-Pekka), Tuomilehto, J. (Jaakko), Tybjaerg-Hansen, A. (Anne), Tzourio, C. (Christophe), Ueda, P. (Peter), Ugel, E. (Eunice), Ulmer, H. (Hanno), Unal, B. (Belgin), Uusitalo, H., Valdivia, G. (Gonzalo), Valvi, D. (Damaskini), Dam, R.M. (Rob) van, Schouw, Y.T. (Yvonne) van der, Van Herck, K. (Koen), Van Minh, H. (Hoang), Rossem, L. (Lenie) van, Schoor, N.M. (Natasja) van, Valkengoed, I. (Irene) van, Vanderschueren, D. (Dirk), Vanuzzo, D. (Diego), Varbo, A. (Anette), Varona-Pérez, P. (Patricia), Vasan, S.K. (Senthil K.), Vatten, L. (Lars), Vega, T. (Tomas), Veidebaum, T. (Toomas), Velasquez-Melendez, G. (Gustavo), Venero-Fernández, S.J. (Silvia J.), Veronesi, G. (Giovanni), Verschuren, W.M.M. (W. M. Monique), Victora, C.G. (Cesar G.), Vidiawati, D. (Dhanasari), Viet, L. (Lucie), Villalpando, S. (Salvador), Vioque, J. (Jesus), Virtanen, J.K. (Jyrki K.), Visvikis-Siest, S. (Sophie), Viswanathan, B. (Bharathi), Vlasoff, T. (Tiina), Vollenweider, P. (Peter), Voutilainen, A. (Ari), Wade, A.N. (Alisha N.), Wagner, A. (Aline), Walton, J. (Janette), Bebakar, W.M.W. (Wan Mohamad Wan), Mohamud, W.N.W. (Wan Nazaimoon Wan), Wang, M.-D. (Ming-Dong), Wang, N. (Ningli), Wang, Q. (Qian), Wang, Y.X. (Ya Xing), Wang, Y.-W. (Ying-Wei), Wannamethee, S.G. (Goya), Wedderkopp, N. (Niels), Wei, W. (Wenbin), Whincup, P.H. (Peter), Widhalm, K. (Kurt), Widyahening, I.S. (Indah S.), Wiecek, A. (Andrzej), Wijga, A.H. (Alet), Wilks, R.J. (Rainford J.), Willeit, J. (Johann), Willeit, P. (Peter), Wilsgaard, T. (Tom), Wojtyniak, B. (Bogdan), Wong-McClure, R.A. (Roy A.), Wong, A. (Andrew), Wong, T.Y. (Tien Yin), Woo, J. (Jean), Woodward, M. (Mark), Wu, F.C. (Frederick C.), Wu, S. (Shouling), Xu, H. (Haiquan), Xu, L. (Liang), Yan, W. (Weili), Yang, X. (Xiaoguang), Yasuharu, T. (Tabara), Ye, X. (Xingwang), Yeow, T.P. (Toh Peng), Yiallouros, P.K. (P.), Yoosefi, M. (Moein), Yoshihara, A. (Akihiro), You, S.-L. (San-Lin), Younger-Coleman, N.O. (Novie O.), Yusoff, A.F. (Ahmad Faudzi), Zainuddin, A.A. (Ahmad A.), Zakavi, S.R. (Seyed Rasoul), Zali, M.R. (Mohammad Reza), Zamani, F. (Farhad), Zambon, S. (Sabina), Zampelas, A. (Antonis), Zaw, K.K. (Ko Ko), Zdrojewski, T. (T.), Vrkic, T.Z. (Tajana Zeljkovic), Zhang, Z.-Y. (Zhen-Yu), Zhao, W. (Wenhua), Zhen, S. (Shiqi), Zheng, Y. (Yingfeng), Zholdin, B. (Bekbolat), Zhussupov, B. (Baurzhan), Zoghlami, N. (Nada), Cisneros, J.Z. (Julio Zuñiga), Gregg, E.W. (Edward W.), Ezzati, M. (Majid), Taddei, C. (Cristina), Zhou, B. (Bin), Bixby, H. (Honor), Carrillo-Larco, R.M. (Rodrigo M.), Danaei, G. (Goodarz), Jackson, R.T. (Rod T.), Farzadfar, F. (Farshad), Sophiea, M.K. (Marisa K.), Di Cesare, M. (Mariachiara), Iurilli, M.L.C. (Maria Laura Caminia), Martinez, A.R. (Andrea Rodriguez), Asghari, G. (Golaleh), Dhana, K. (Klodian), Gulayin, P. (Pablo), Kakarmath, S. (Sujay), Santero, M. (Marilina), Voortman, R.G. (Trudy), Riley, L.M. (Leanne M.), Cowan, M.J. (Melanie J.), Savin, S. (Stefan), Bennett, J.E. (James E.), Stevens, G.A. (Gretchen A.), Paciorek, C.J. (Christopher J.), Aekplakorn, W. (Wichai), Cifkova, R. (Renata), Giampaoli, S. (Simona), Kengne, A.P. (Andre Pascal), Khang, Y.-H. (Young-Ho), Kuulasmaa, K. (Kari), Laxmaiah, A. (Avula), Margozzini, P. (Paula), Mathur, P. (Prashant), Nordestgaard, B.G. (Børge), Zhao, D. (Dong), Aadahl, M. (Mette), Abarca-Gómez, L. (Leandra), Rahim, H.A. (Hanan Abdul), Abu-Rmeileh, N.M. (Niveen M.), Acosta-Cazares, B. (Benjamin), Adams, R.J. (Robert J.), Agdeppa, I.A. (Imelda A.), Aghazadeh-Attari, J. (Javad), Aguilar-Salinas, C.A. (Carlos A.), Agyemang, C.O. (Charles), Ahluwalia, T.S. (Tarunveer Singh), Ahmad, N.A. (Noor Ani), Ahmadi, A. (Ali), Ahmadi, N. (Naser), Ahmed, S.H. (Soheir H.), Ahrens, W. (W.), Ajlouni, K. (Kamel), Alarouj, M. (Monira), AlBuhairan, F. (Fadia), AlDhukair, S. (Shahla), Ali, M.M. (Mohamed M.), Alkandari, A. (Abdullah), Alkerwi, A. (Ala’a), Aly, E. (Eman), Amarapurkar, D.N. (Deepak N.), Amouyel, P. (Philippe), Andersen, L.B. (Lars Bo), Anderssen, S.A. (Sigmund A.), Anjana, R.M. (Ranjit Mohan), Ansari-Moghaddam, A. (Alireza), Aounallah-Skhiri, H. (Hajer), Araújo, J. (Joana), Ariansen, I. (Inger), Aris, T. (Tahir), Arku, R.E. (Raphael E.), Arlappa, N. (Nimmathota), Aryal, K.K. (Krishna K.), Aspelund, T. (Thor), Assunção, M.C.F. (Maria Cecília F.), Auvinen, J. (Juha), Avdicová, M. (Mária), Azevedo, A. (Ana), Azizi, J. (Joshan), Azmin, M. (Mehrdad), Balakrishna, N. (Nagalla), Bamoshmoosh, M. (Mohamed), Banach, M. (Maciej), Bandosz, P. (Piotr), Banegas, J.R. (José R.), Barbagallo, C.M. (Carlo M.), Barceló, A. (Alberto), Barkat, A. (Amina), Bata, I. (Iqbal), Batieha, A.M. (Anwar M.), Batyrbek, A. (Assembekov), Baur, L.A. (Louise A.), Beaglehole, R. (Robert), Belavendra, A. (Antonisamy), Ben Romdhane, H. (Habiba), Benet, M. (Mikhail), Benn, M. (Marianne), Berkinbayev, S. (Salim), Bernabe-Ortiz, A. (Antonio), Bernotiene, G. (Gailute), Bettiol, H. (Heloisa), Bhargava, S.K. (Santosh K.), Bi, Y. (Yufang), Bienek, A. (Asako), Bikbov, M. (Mukharram), Bista, B. (Bihungum), Bjerregaard, P. (Peter), Bjertness, E. (Espen), Bjertness, M.B. (Marius B.), Björkelund, C. (Cecilia), Bloch, K.V. (Katia V.), Blokstra, A. (Anneke), Bo, S. (Simona), Boehm, B.O. (Bernhard O.), Boggia, J.G. (Jose G.), Boissonnet, C.P. (Carlos P.), Bonaccio, M. (Marialaura), Bongard, V. (Vanina), Borchini, R. (Rossana), Borghs, H. (Herman), Bovet, P. (Pascal), Brajkovich, I. (Imperia), Breckenkamp, J. (Juergen), Brenner, H. (Hermann), Brewster, L.M. (Lizzy), Bruno, G. (Graziella), Bugge, A. (Anna), Busch, M.A. (Markus A.), de León, A.C. (Antonio Cabrera), Cacciottolo, J. (Joseph), Can, G. (Günay), Cândido, A.P.C. (Ana Paula C.), Capanzana, M.V. (Mario V.), Capuano, E. (Eduardo), Capuano, V. (Vincenzo), Cardoso, V.C. (Viviane C.), Carvalho, J. (Joana), Casanueva, F.F., Censi, L. (Laura), Chadjigeorgiou, C.A. (Charalambos A.), Chamukuttan, S. (Snehalatha), Chaturvedi, N. (Nish), Chen, C.-J. (Chien-Jen), Chen, F. (Fangfang), Chen, S. (Shuohua), Cheng, C.-Y. (Ching-Yu), Cheraghian, B. (Bahman), Chetrit, A. (Angela), Chiou, S.-T. (Shu-Ti), Chirlaque, M.D. (M.), Cho, B. (Belong), Cho, Y. (Yumi), Chudek, J. (Jerzy), Claessens, F. (Frank), Clarke, J. (Janine), Clays, E. (Els), Concin, H. (Hans), Confortin, S.C. (Susana C.), Cooper, C. (Charles), Costanzo, S. (Simona), Cottel, D. (Dominique), Cowell, C. (Chris), Crujeiras, A.B. (Ana B.), Csilla, S. (Semánová), Cui, L. (Liufu), Cureau, F.V. (Felipe V.), D’Arrigo, G. (Graziella), d’Orsi, E. (Eleonora), Dallongeville, J., Damasceno, A. (Albertino), Dankner, R. (Rachel), Dantoft, T.M. (Thomas M.), Dauchet, L. (Luc), Davletov, K. (Kairat), Backer, G. (Guy) de, Bacquer, D. (Dirk) de, de Gaetano, G. (Giovanni), De Henauw, S. (Stefaan), de Oliveira, P.D. (Paula Duarte), De Ridder, D. (David), De Smedt, D. (Delphine), Deepa, M. (Mohan), Deev, A.D. (Alexander D.), Dehghan, A. (Abbas), Delisle, H. (Hélène), Dennison, E.M. (Elaine), Deschamps, V. (Valérie), Dhimal, M. (Meghnath), Di Castelnuovo, A.F. (Augusto F.), Dika, Z. (Zivka), Djalalinia, S. (Shirin), Dobson, A.J. (Annette J.), Donfrancesco, C. (Chiara), Donoso, S.P. (Silvana P.), Döring, A. (Angela), Dorobantu, M. (Maria), Dragano, N. (Nico), Drygas, W. (Wojciech), Du, Y. (Yong), Duante, C.A. (Charmaine A.), Duda, R.B. (Rosemary B.), Dzerve, V. (Vilnis), Dziankowska-Zaborszczyk, E. (Elzbieta), Eddie, R. (Ricky), Eftekhar, E. (Ebrahim), Eggertsen, R. (Robert), Eghtesad, S. (Sareh), Eiben, G. (Gabriele), Ekelund, U. (Ulf), El Ati, J. (Jalila), Eldemire-Shearer, D. (Denise), Eliasen, M. (Marie), Elosua, R. (Roberto), Erasmus, R.T. (Rajiv T.), Erbel, R. (Raimund), Erem, C. (Cihangir), Eriksen, L. (Louise), Hagen, K. (Knut), Escobedo-de la Peña, J. (Jorge), Eslami, S. (Saeid), Esmaeili, A. (Ali), Evans, A. (Alun), Faeh, D. (David), Fall, C.H. (Caroline H.), Faramarzi, E. (Elnaz), Farjam, M. (Mojtaba), Fattahi, M.R. (Mohammad Reza), Felix-Redondo, F.J. (Francisco J.), Ferguson, T.S. (Trevor S.), Fernández-Bergés, D. (Daniel), Ferrante, D. (Daniel), Ferrari, M. (Marika), Ferreccio, C. (Catterina), Ferrieres, J. (Jean), Föger, B. (Bernhard), Foo, L.H. (Leng Huat), Forslund, A.-S. (Ann-Sofie), Forsner, M. (Maria), Fouad, H.M. (Heba M.), Francis, D.K. (Damian K.), do Carmo Franco, M. (Maria), Franco, O.H. (Oscar H.), Frontera, G. (Guillermo), Fujita, Y. (Yuki), Fumihiko, M. (Matsuda), Furusawa, T. (Takuro), Gaciong, Z. (Zbigniew), Galvano, F. (Fabio), Gao, J. (Jingli), Garcia-de-la-Hera, M. (Manoli), Garnett, S.P. (Sarah P.), Gaspoz, J.-M. (Jean-Michel), Gasull, M. (Magda), Gazzinelli, A. (Andrea), Geleijnse, J.M. (Marianne), Ghanbari, A. (Ali), Ghasemi, E. (Erfan), Gheorghe-Fronea, O.-F. (Oana-Florentina), Ghimire, A. (Anup), Gianfagna, F. (Francesco), Gill, T.K. (Tiffany K.), Giovannelli, J. (Jonathan), Gironella, G. (Glen), Giwercman, A. (Aleksander), Goltzman, D. (David), Gonçalves, H. (Helen), Gonzalez-Chica, D.A. (David A.), Gonzalez-Gross, M. (Marcela), González-Rivas, J.P. (Juan P.), González-Villalpando, C. (Clicerio), González-Villalpando, M.E. (María Elena), Gonzalez, A.R. (Angel R.), Gottrand, F., Graff-Iversen, S. (Sidsel), Grafnetter, D. (Dušan), Gregor, R.D. (Ronald D.), Grodzicki, T. (Tomasz), Grøntved, A. (Anders), Grosso, G. (Giuseppe), Gruden, G. (Gabriella), Gu, D. (Dongfeng), Guallar-castillón, P. (Pilar), Guan, O.P. (Ong Peng), Gudmundsson, E.F. (Elias F.), Gudnason, V. (Vilmundur), Guerrero, R. (Ramiro), Guessous, I. (Idris), Gunnlaugsdottir, J. (Johanna), Gupta, R. (Rajeev), Gutierrez, L. (Laura), Gutzwiller, F. (Felix), Ha, S. (Seongjun), Hadaegh, F. (Farzad), Haghshenas, R. (Rosa), Hakimi, H. (Hamid), Hambleton, I.R. (Ian R.), Hamzeh, B. (Behrooz), Hantunen, S. (Sari), Kumar, R.H. (Rachakulla Hari), Hashemi-Shahri, S.M. (Seyed Mohammad), Hata, J. (Jun), Haugsgjerd, T. (Teresa), Hayes, A.J. (Alison J.), He, J. (Jiang), He, Y. (Yong), Hendriks, M.E. (Marleen), Henriques, A. (Ana), Herrala, S. (Sauli), Heshmat, R. (Ramin), Hill, A.G. (Allan G.), Ho, S.Y. (Sai Yin), Ho, S.C. (Suzanne C.), Hobbs, M. (Michael), Hofman, A. (Albert), Homayounfar, R. (Reza), Hopman, W.M. (Wilma M.), Horimoto, A.R.V.R. (Andrea R. V. R.), Hormiga, C.M. (Claudia M.), Horta, B.L. (Bernardo L.), Houti, L. (Leila), Howitt, C. (Christina), Htay, T.T. (Thein Thein), Htet, A.S. (Aung Soe), Htike, M.M.T. (Maung Maung Than), Huerta, J.M. (José María), Huhtaniemi, I.T. (I.), Huisman, M. (Martijn), Hunsberger, M.L. (Monica L.), Husseini, A. (Abdullatif), Huybrechts, I. (Inge), Hwalla, N. (Nahla), Iacoviello, L. (Licia), Iannone, A.G. (Anna G.), Ibrahim, M.M. (Mohsen), Wong, N.I. (Norazizah Ibrahim), Iglesia, I. (Iris), Ikeda, N. (Nayu), Ikram, M.A. (Arfan), Iotova, V. (Violeta), Irazola, V.E. (Vilma E.), Ishida, T. (Takafumi), Islam, M. (Muhammad), al-Safi Ismail, A. (Aziz), Iwasaki, M. (Masanori), Jacobs, J.M. (Jeremy M.), Jaddou, H.Y. (Hashem Y.), Jafar, T.H. (Tazeen), James, K. (Kenneth), Jamrozik, K., Janszky, I. (Imre), Janus, E. (Edward), Jarvelin, M.-R. (Marjo-Riitta), Jasienska, G. (Grazyna), Jelakovic, A. (Ana), Jelakovic, B. (Bojan), Jennings, G. (Garry), Jensen, G.B. (Gorm), Jeong, S.-L. (Seung-lyeal), Jha, A.K. (Anjani Kumar), Jiang, C.Q. (Chao Qiang), Jimenez, R.O. (Ramon O.), JöCkel, K.-H. (Karl-Heinz), Joffres, M. (Michel), Jokelainen, J.J. (Jari J.), Jonas, J.B. (Jost B.), Jorgensen, T. (Torben), Joshi, P. (Pradeep), Joukar, F. (Farahnaz), Józwiak, J. (Jacek), Juolevi, A. (Anne), Kafatos, A. (Anthony), Kajantie, E. (Eero), Kalter-Leibovici, O. (Ofra), Kamaruddin, N.A. (Nor Azmi), Kamstrup, P.R. (Pia R.), Karki, K.B. (Khem B.), Katz, J. (Joanne), Kauhanen, J. (Jussi), Kaur, P. (Prabhdeep), Kavousi, M. (Maryam), Kazakbaeva, G. (Gyulli), Keil, M. (Mark), Keinanen-Kiukaanniemi, S. (Sirkka), Kelishadi, R. (Roya), Keramati, M. (Maryam), Kerimkulova, A. (Alina), Kersting, M. (Mathilde), Khader, Y.S. (Yousef Saleh), Khalili, D. (Davood), Khateeb, M. (Mohammad), Kheradmand, M. (Motahareh), Khosravi, A. (Alireza), Kiechl-Kohlendorfer, U. (Ursula), Kiechl, S. (Stefan), Killewo, J. (Japhet), Kim, H.C. (Hyeon Chang), Kim, J. (Jeongseon), Kim, Y.-Y. (Yeon-Yong), Klumbiene, J. (Jurate), Knoflach, M. (Michael), Ko, S. (Stephanie), Kohler, H.-P. (Hans-Peter), Kohler, I.V. (Iliana V.), Kolle, E. (Elin), Kolsteren, P. (Patrick), König, J. (Jürgen), Korpelainen, R. (Raija), Korrovits, P. (Paul), Kos, J. (Jelena), Koskinen, S. (Seppo), Kouda, K. (Katsuyasu), Kowlessur, S. (Sudhir), Kratzer, W. (Wolfgang), Kriemler, S. (Susi), Kristensen, P.L. (Peter Lund), Krokstad, S. (Steiner), Kromhout, D. (Daan), Kujala, U.M. (Urho), Kurjata, P. (Pawel), Kyobutungi, C. (Catherine), Laamiri, F.Z. (Fatima Zahra), Laatikainen, T. (Tiina), Lachat, C. (Carl), Laid, Y. (Youcef), Lam, T.H. (Tai Hing), Lambrinou, C.-P. (Christina-Paulina), Lanska, V. (Vera), Lappas, G. (Georg), Larijani, B. (Bagher), Latt, T.S. (Tint Swe), Laugsand, L.E. (Lars E.), Lazo-Porras, M. (Maria), Lee, J. (Jeannette), Lee, J. (Jeonghee), Lehmann, N. (Nils), Lehtimäki, T. (Terho), Levitt, N.S. (Naomi S.), Li, Y. (Yanping), Lilly, C.L. (Christa L.), Lim, W.-Y. (Wei-Yen), Lima-Costa, M.F. (Maria Fernanda), Lin, H.-H. (Hsien-Ho), Lin, X. (Xu), Lin, Y.-T. (Yi-Ting), Kao, W.H.L. (Wen), Linneberg, A. (Allan), Lissner, L. (Lauren), Liu, J. (Jing), Loit, H.-M. (Helle-Mai), Lopez-Garcia, E. (Esther), Lopez, T. (Tania), Lotufo, P.A. (Paulo A), Lozano, J.E. (José Eugenio), Luksiene, D. (Dalia), Lundqvist, A. (Annamari), Lundqvist, R. (Robert), Lunet, N. (Nuno), Ma, G. (Guansheng), Machado-Coelho, G.L.L. (George L. L.), Machado-Rodrigues, A.M. (Aristides M.), Machi, S. (Suka), Madar, A.A. (Ahmed A.), Maggi, S. (Stefania), Magliano, D.J., Magriplis, E. (Emmanuella), Mahasampath, G. (Gowri), Maire, B. (Bernard), Makdisse, M. (Marcia), Malekzadeh, F. (Fatemeh), Malekzadeh, R. (Reza), Rao, K.M. (Kodavanti Mallikharjuna), Manios, Y., Mann, J.I. (Jim I.), Mansour-Ghanaei, F. (Fariborz), Manzato, E. (Enzo), Marques-Vidal, P. (Pedro), Martorell, R. (Reynaldo), Mascarenhas, L.P. (Luis P.), Mathiesen, E.B. (Ellisiv), Matsha, T.E. (Tandi E.), Mavrogianni, C. (Christina), McFarlane, S.R. (Shelly R.), McGarvey, S.T. (Stephen T.), McLachlan, S. (Stela), McLean, R.M. (Rachael M.), McLean, S.B. (Scott B.), McNulty, B.A. (Breige A.), Mediene-Benchekor, S. (Sounnia), Mehdipour, P. (Parinaz), Mehlig, K. (Kirsten), Mehrparvar, A.H. (Amir Houshang), Meirhaeghe, A. (Aline), Meisinger, C. (Christa), Menezes, A.M.B. (Ana M.B.), Menon, G.R. (Geetha R.), Merat, S. (Shahin), Mereke, A. (Alibek), Meshram, I.I. (Indrapal I.), Metcalf, P. (Patricia), Meyer, H.E. (Haakon E.), Mi, J. (Jie), Michels, N. (Nathalie), Miller, J.C. (Jody C.), Minderico, C.S. (Cláudia S.), Mini, G.K. (G. K.), Miquel, J.F. (Juan Francisco), Miranda, J.J. (J. Jaime), Mirjalili, M.R. (Mohammad Reza), Mirrakhimov, E. (Erkin), Modesti, P.A. (Pietro A.), Moghaddam, S.S. (Sahar Saeedi), Mohajer, B. (Bahram), Mohamed, M.K. (Mostafa K.), Mohammad, K. (Kazem), Mohammadi, Z. (Zahra), Mohammadifard, N. (Noushin), Mohammadpourhodki, R. (Reza), Mohan, V. (Viswanathan), Mohanna, S. (Salim), Yusoff, M.F.M. (Muhammad Fadhli Mohd), Mohebbi, I. (Iraj), Mohebi, F. (Farnam), Moitry, M. (Marie), Møllehave, L.T. (Line T.), Møller, N.C. (Niels C.), Molnár, D. (Dénes), Momenan, A. (Amirabbas), Mondo, C.K. (Charles K.), Monterrubio-Flores, E. (Eric), Moosazadeh, M. (Mahmood), Morejon, A. (Alain), Moreno, L. (Luis), Morgan, K. (Karen), Morin, S.N. (Suzanne N.), Moschonis, G. (George), Mossakowska, M. (Malgorzata), Mostafa, A. (Aya), Mota, J. (Jorge), Motlagh, M.E. (Mohammad Esmaeel), Motta, J. (Jorge), Msyamboza, K.P. (Kelias P.), Muiesan, M.L. (Maria Lorenza), Müller-Nurasyid, M. (Martina), Mursu, J. (Jaakko), Mustafa, N. (Norlaila), Nabipour, I. (Iraj), Naderimagham, S. (Shohreh), Nagel, G. (Gabriele), Naidu, B.M. (Balkish M.), Najafi, F. (Farid), Nakamura, H. (Harunobu), Námešná, J. (Jana), Nang, E.E.K. (Ei Ei K.), Nangia, V.B. (Vinay B.), Nauck, M. (Matthias), Neal, W.A. (William A.), Nejatizadeh, A. (Azim), Nenko, I. (Ilona), Nervi, F. (Flavio), Nguyen, N.D. (Nguyen D.), Nguyen, Q.N. (Quang Ngoc), Nieto-Martínez, R.E. (Ramfis E.), Nihal, T. (Thomas), Niiranen, T.J. (Teemu J.), Ning, G. (Guang), Ninomiya, T. (Toshiharu), Noale, M. (Marianna), Noboa, O.A. (Oscar A.), Noto, D. (Davide), Nsour, M.A. (Mohannad Al), Nuhoğlu, I. (Irfan), O’Neill, T.W. (Terence W.), O’Reilly, D. (Dermot), Ochoa-Avilés, A.M. (Angélica M.), Oh, K. (Kyungwon), Ohtsuka, R. (Ryutaro), Olafsson, Ö. (Örn), Olié, V. (Valérie), Oliveira, I.O. (Isabel O.), Omar, M.A. (Mohd Azahadi), Onat, A. (Altan), Ong, S.K. (Sok King), Ordunez, P. (Pedro), Ornelas, R. (Rui), Ortiz, P.J. (Pedro J.), Osmond, C. (Clive), Ostojic, S.M. (Sergej M.), Ostovar, A. (Afshin), Otero, J.A. (Johanna A.), Owusu-Dabo, E. (Ellis), Paccaud, F.M. (Fred Michel), Pahomova, E. (Elena), Pajak, A. (Andrzej), Palmieri, L. (Luigi), Pan, W.-H. (Wen-Harn), Panda-Jonas, S. (Songhomitra), Panza, F. (Francesco), Parnell, W.R. (Winsome R.), Patel, N.D. (Nikhil D.), Peer, N. (Nasheeta), Peixoto, S.V. (Sergio Viana), Peltonen, M. (Markku), Pereira, A. (A.), Peters, A. (Annette), Petersmann, A. (Astrid), Petkeviciene, J. (Janina), Peykari, N. (Niloofar), Pham, S.T. (Son Thai), Pichardo, R.N. (Rafael N.), Pigeot, I. (Iris), Pilav, A. (Aida), Pilotto, A. (Alberto), Piwonska, A. (Aleksandra), Pizarro, A.N. (Andreia N.), Plans-Rubió, P. (Pedro), Plata, S. (Silvia), Pohlabeln, H. (Hermann), Porta, M. (Miquel), Portegies, M.L.P. (Marileen), Poudyal, A. (Anil), Pourfarzi, F. (Farhad), Poustchi, H. (Hossein), Pradeepa, R. (Rajendra), Price, J.F. (Jacqueline F.), Providencia, R. (Rui), Puder, J.J. (Jardena J.), Puhakka, S.E. (Soile E.), Punab, M. (Margus), Qorbani, M. (Mostafa), Bao, T.Q. (Tran Quoc), Radisauskas, R. (Ricardas), Rahimikazerooni, S. (Salar), Raitakari, O. (Olli), Rao, S.R. (Sudha Ramachandra), Ramachandran, A. (Ambady), Ramos, E. (Elisabete), Ramos, R. (Rafel), Rampal, L. (Lekhraj), Rampal, S. (Sanjay), Redón, J. (Josep), Reganit, P.F.M. (Paul Ferdinand M.), Revilla, L. (Luis), Rezaianzadeh, A. (Abbas), Ribeiro, R. (Robespierre), Richter, A. (Adrian), Rigo, F. (Fernando), Rinke de Wit, T.F. (Tobias), Rodríguez Artalejo, F. (Fernando), del Cristo Rodriguez-Perez, M. (María), Rodríguez-Villamizar, L.A. (Laura A.), Roggenbuck, U. (Ulla), Rojas-Martinez, R. (Rosalba), Romaguera, D. (Dora), Romeo, E.L. (Elisabetta L.), Rosengren, A. (Annika), Roy, J.G.R. (Joel G. R.), Rubinstein, A. (Adolfo), Ruidavets, J.-B. (Jean-Bernard), Ruiz-Betancourt, B.S. (Blanca Sandra), Russo, P. (Paola), Rust, P. (Petra), Rutkowski, M. (Marcin), Sabanayagam, C. (Charumathi), Sachdev, H.S. (Harshpal S.), Sadjadi, A. (Alireza), Safarpour, A.R. (Ali Reza), Safiri, S. (Saeid), Saidi, O. (Olfa), Saki, N. (Nader), Salanave, B. (Benoit), Salmerón, D. (Diego), Salomaa, V. (Veikko), Salonen, J.T. (Jukka T.), Salvetti, M. (Massimo), Sánchez-Abanto, J. (Jose), Sans, S. (Susana), Santaliestra-Pasías, A.M. (Alba M.), Santos, D.A. (Diana A.), Santos, M.P. (Maria Paula), Santos, R. (Rute), Saramies, J.L. (Jouko L.), Sardinha, L.B. (Luis B.), Sarrafzadegan, N. (Nizal), Saum, K.-U. (Kai-Uwe), Savva, S., Sawada, N. (Norie), Sbaraini, M. (Mariana), Scazufca, M. (Marcia), Schaan, B.D. (Beatriz D.), Schargrodsky, H. (Herman), Scheidt-Nave, C. (C.), Schienkiewitz, A. (Anja), Schipf, S. (Sabine), Schmidt, C.O. (Carsten O.), Schöttker, B. (Ben), Schramm, S. (Sara), Sebert, S. (Sylvain), Sein, A.A. (Aye Aye), Sen, A. (Abhijit), Sepanlou, S.G. (Sadaf G), Servais, J. (Jennifer), Shakeri, R. (Ramin), Shalnova, S.A. (Svetlana A.), Shamah-Levy, T. (Teresa), Sharafkhah, M. (Maryam), Sharma, S.K. (Sanjib K.), Shaw, J.E., Shayanrad, A. (Amaneh), Shi, Z. (Zumin), Shibuya, K. (Kenji), Shimizu-Furusawa, H. (Hana), Shin, D.W. (Dong Wook), Shin, Y. (Youchan), Shirani, M. (Majid), Shiri, R. (Rahman), Shrestha, N. (Namuna), Si-Ramlee, K. (Khairil), Siani, A. (Alfonso), Siantar, R. (Rosalynn), Sibai, A.M. (Abla M.), Silva, D.A.S. (Diego Augusto Santos), Simon, M. (Mary), Simons, J. (Judith), Simons, L.A. (Leon A.), Sjöström, M. (Michael), Skaaby, T. (Tea), Slowikowska-Hilczer, J. (Jolanta), Slusarczyk, P. (Przemyslaw), Smeeth, L. (Liam), Snijder, M.B. (Marieke), Söderberg, S. (Stefan), Soemantri, A. (Augustinus), Sofat, R. (Reecha), Solfrizzi, V. (Vincenzo), Somi, M.H. (Mohammad Hossein), Sonestedt, E. (Emily), Sørensen, T.I.A. (Thorkild), Jérome, C.S. (Charles Sossa), Soumaré, A. (Aicha), Sozmen, K. (Kaan), Sparrenberger, K. (Karen), Staessen, J.A. (Jan), Stathopoulou, M.G. (Maria G), Stavreski, B. (Bill), Steene-Johannessen, J. (Jostein), Stehle, P. (Peter), Stein, A.D. (Aryeh D.), Stessman, J. (Jochanan), Stevanović, R. (Ranko), Stieber, J. (Jutta), Stöckl, D. (Doris), Stokwiszewski, J. (Jakub), Stronks, K. (Karien), Strufaldi, M.W. (Maria Wany), Suárez-Medina, R. (Ramón), Sun, C.-A. (Chien-An), Sundström, J. (Johan), Suriyawongpaisal, P. (Paibul), Sy, R.G. (Rody G.), Sylva, R.C. (René Charles), Szklo, M. (Moyses), Tai, E.S. (Shyong), Tamosiunas, A. (Abdonas), Tan, E.J. (Eng Joo), Tarawneh, M.R. (Mohammed Rasoul), Tarqui-Mamani, C.B. (Carolina B.), Taylor, A. (Anne), Taylor, J. (Julie), Tell, G.S. (Grethe S.), Tello, T. (Tania), Thankappan, K.R. (K. R.), Thijs, L. (Lutgarde), Thuesen, B.H. (Betina H.), Toft, U. (Ulla), Tolonen, H.K. (Hanna K.), Tolstrup, J.S. (Janne), Topbas, M. (Murat), Topór-Madry, R. (Roman), Tormo, M.J., Tornaritis, M.J. (Michael J.), Torrent, M. (Maties), Torres-Collado, L. (Laura), Traissac, P. (Pierre), Trinh, O.T.H. (Oanh T. H.), Truthmann, J. 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- Abstract
High blood cholesterol is typically considered a feature of wealthy western countries1,2. However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world3 and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health4,5. However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol—which is a marker of cardiov
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- 2020
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10. Prevalence, awareness, treatment and control of hypertension in Taiwan: results of Nutrition and Health Survey in Taiwan (NAHSIT) 1993–1996
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Pan, W-H, Chang, H-Y, Yeh, W-T, Hsiao, S-Y, and Hung, Y-T
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- 2001
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11. Effects of urate-lowering therapy on cardiovascular mortality: a propensity score matched case-control study: 703637
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CHEN, J H, YEH, W T, and PAN, W H
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- 2012
12. Elastic In-Plane Buckling of Funicular Arches
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Pan, W. H., primary and Wang, C. M., additional
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- 2020
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13. Lower-caloric intake but different nutrient profiles in cognition impaired and in frail elderlies
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Wu, S Y, primary and Pan, W H, additional
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- 2020
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14. Optimal Design of Triangular Arches against Buckling
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Wang, C. M., primary, Pan, W. H., additional, and Zhang, J. Q., additional
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- 2020
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15. Hencky Bar-Chain/Net for Structural Analysis
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Wang, C M, primary, Zhang, H, additional, Challamel, N, additional, and Pan, W H, additional
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- 2020
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16. High sugar-sweetened beverage intake frequency is associated with smoking, irregular meal intake and higher serum uric acid in Taiwanese adolescents
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Shih, Y. H., primary, Chang, H. Y., additional, Wu, H. C., additional, Stanaway, F. F, additional, and Pan, W. H., additional
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- 2020
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17. Adequately Rigid Cross Beams for Bridge Tower Designs
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Pan, W. H., primary, Wang, Jia-Ji, additional, Nie, Xin, additional, and Tong, J. Z., additional
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- 2019
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18. Impact of urate lowering therapy on the risk of cardiovascular disease mortality: a prospective Taiwanese cohort study: 0803
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Chen, J H, Chou, W L, and Pan, W H
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- 2010
19. Incidence of NIDDM and the effects of gender, obesity and hyperinsulinaemia in Taiwan
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Wang, S.-L., Pan, W.-H., Hwu, C.-M., Ho, L.-T., Lo, C.-H., Lin, S.-L., and Jong, Y.-S.
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- 1997
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20. Obesity pandemic, correlated factors and guidelines to define, screen and manage obesity in Taiwan
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Pan, W.-H., Lee, M.-S., Chuang, S.-Y., Lin, Y.-C., and Fu, M.-L.
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- 2008
21. Sexual differences in bone markers and bone mineral density of normal Chinese
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Tsai, K. S., Pan, W. H., Hsu, S. H. J., Cheng, W. C., Chen, C. K., Chieng, P. U., Yang, R. S., and Twu, S. T.
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- 1996
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22. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
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Feigin, V.L. Nichols, E. Alam, T. Bannick, M.S. Beghi, E. Blake, N. Culpepper, W.J. Dorsey, E.R. Elbaz, A. Ellenbogen, R.G. Fisher, J.L. Fitzmaurice, C. Giussani, G. Glennie, L. James, S.L. Johnson, C.O. Kassebaum, N.J. Logroscino, G. Marin, B. Mountjoy-Venning, W.C. Nguyen, M. Ofori-Asenso, R. Patel, A.P. Piccininni, M. Roth, G.A. Steiner, T.J. Stovner, L.J. Szoeke, C.E.I. Theadom, A. Vollset, S.E. Wallin, M.T. Wright, C. Zunt, J.R. Abbasi, N. Abd-Allah, F. Abdelalim, A. Abdollahpour, I. Aboyans, V. Abraha, H.N. Acharya, D. Adamu, A.A. Adebayo, O.M. Adeoye, A.M. Adsuar, J.C. Afarideh, M. Agrawal, S. Ahmadi, A. Ahmed, M.B. Aichour, A.N. Aichour, I. Aichour, M.T.E. Akinyemi, R.O. Akseer, N. Al-Eyadhy, A. Al-Shahi Salman, R. Alahdab, F. Alene, K.A. Aljunid, S.M. Altirkawi, K. Alvis-Guzman, N. Anber, N.H. Antonio, C.A.T. Arabloo, J. Aremu, O. Ärnlöv, J. Asayesh, H. Asghar, R.J. Atalay, H.T. Awasthi, A. Ayala Quintanilla, B.P. Ayuk, T.B. Badawi, A. Banach, M. Banoub, J.A.M. Barboza, M.A. Barker-Collo, S.L. Bärnighausen, T.W. Baune, B.T. Bedi, N. Behzadifar, M. Behzadifar, M. Béjot, Y. Bekele, B.B. Belachew, A.B. Bennett, D.A. Bensenor, I.M. Berhane, A. Beuran, M. Bhattacharyya, K. Bhutta, Z.A. Biadgo, B. Bijani, A. Bililign, N. Bin Sayeed, M.S. Blazes, C.K. Brayne, C. Butt, Z.A. Campos-Nonato, I.R. Cantu-Brito, C. Car, M. Cárdenas, R. Carrero, J.J. Carvalho, F. Castañeda-Orjuela, C.A. Castro, F. Catalá-López, F. Cerin, E. Chaiah, Y. Chang, J.-C. Chatziralli, I. Chiang, P.P.-C. Christensen, H. Christopher, D.J. Cooper, C. Cortesi, P.A. Costa, V.M. Criqui, M.H. Crowe, C.S. Damasceno, A.A.M. Daryani, A. De la Cruz-Góngora, V. De La Hoz, F.P. De Leo, D. Degefa, M.G. Demoz, G.T. Deribe, K. Dharmaratne, S.D. Diaz, D. Dinberu, M.T. Djalalinia, S. Doku, D.T. Dubey, M. Dubljanin, E. Duken, E.E. Edvardsson, D. El-Khatib, Z. Endres, M. Endries, A.Y. Eskandarieh, S. Esteghamati, A. Esteghamati, S. Farhadi, F. Faro, A. Farzadfar, F. Farzaei, M.H. Fatima, B. 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Khang, Y.-H. Khazaie, H. Kiadaliri, A.A. Kiirithio, D.N. Kim, A.S. Kim, D. Kim, Y.-E. Kim, Y.J. Kisa, A. Kokubo, Y. Koyanagi, A. Krishnamurthi, R.V. Kuate Defo, B. Kucuk Bicer, B. Kumar, M. Lacey, B. Lafranconi, A. Lansingh, V.C. Latifi, A. Leshargie, C.T. Li, S. Liao, Y. Linn, S. Lo, W.D. Lopez, J.C.F. Lorkowski, S. Lotufo, P.A. Lucas, R.M. Lunevicius, R. Mackay, M.T. Mahotra, N.B. Majdan, M. Majdzadeh, R. Majeed, A. Malekzadeh, R. Malta, D.C. Manafi, N. Mansournia, M.A. Mantovani, L.G. März, W. Mashamba-Thompson, T.P. Massenburg, B.B. Mate, K.K.V. McAlinden, C. McGrath, J.J. Mehta, V. Meier, T. Meles, H.G. Melese, A. Memiah, P.T.N. Memish, Z.A. Mendoza, W. Mengistu, D.T. Mengistu, G. Meretoja, A. Meretoja, T.J. Mestrovic, T. Miazgowski, B. Miazgowski, T. Miller, T.R. Mini, G.K. Mirrakhimov, E.M. Moazen, B. Mohajer, B. Mohammad Gholi Mezerji, N. Mohammadi, M. Mohammadi-Khanaposhtani, M. Mohammadibakhsh, R. Mohammadnia-Afrouzi, M. Mohammed, S. Mohebi, F. Mokdad, A.H. Monasta, L. 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Stokes, M.A. Sufiyan, M.B. Sykes, B.L. Sylaja, P. Tabarés-Seisdedos, R. Te Ao, B.J. Tehrani-Banihashemi, A. Temsah, M.-H. Temsah, O. Thakur, J.S. Thrift, A.G. Topor-Madry, R. Tortajada-Girbés, M. Tovani-Palone, M.R. Tran, B.X. Tran, K.B. Truelsen, T.C. Tsadik, A.G. Tudor Car, L. Ukwaja, K.N. Ullah, I. Usman, M.S. Uthman, O.A. Valdez, P.R. Vasankari, T.J. Vasanthan, R. Veisani, Y. Venketasubramanian, N. Violante, F.S. Vlassov, V. Vosoughi, K. Vu, G.T. Vujcic, I.S. Wagnew, F.S. Waheed, Y. Wang, Y.-P. Weiderpass, E. Weiss, J. Whiteford, H.A. Wijeratne, T. Winkler, A.S. Wiysonge, C.S. Wolfe, C.D.A. Xu, G. Yadollahpour, A. Yamada, T. Yano, Y. Yaseri, M. Yatsuya, H. Yimer, E.M. Yip, P. Yisma, E. Yonemoto, N. Yousefifard, M. Yu, C. Zaidi, Z. Zaman, S.B. Zamani, M. Zandian, H. Zare, Z. Zhang, Y. Zodpey, S. Naghavi, M. Murray, C.J.L. Vos, T. GBD 2016 Neurology Collaborators
- Abstract
Background: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. Methods: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs; the sum of years of life lost [YLLs] and years lived with disability [YLDs]) by age and sex for 15 neurological disorder categories (tetanus, meningitis, encephalitis, stroke, brain and other CNS cancers, traumatic brain injury, spinal cord injury, Alzheimer's disease and other dementias, Parkinson's disease, multiple sclerosis, motor neuron diseases, idiopathic epilepsy, migraine, tension-type headache, and a residual category for other less common neurological disorders) in 195 countries from 1990 to 2016. DisMod-MR 2.1, a Bayesian meta-regression tool, was the main method of estimation of prevalence and incidence, and the Cause of Death Ensemble model (CODEm) was used for mortality estimation. We quantified the contribution of 84 risks and combinations of risk to the disease estimates for the 15 neurological disorder categories using the GBD comparative risk assessment approach. Findings: Globally, in 2016, neurological disorders were the leading cause of DALYs (276 million [95% UI 247–308]) and second leading cause of deaths (9·0 million [8·8–9·4]). The absolute number of deaths and DALYs from all neurological disorders combined increased (deaths by 39% [34–44] and DALYs by 15% [9–21]) whereas their age-standardised rates decreased (deaths by 28% [26–30] and DALYs by 27% [24–31]) between 1990 and 2016. The only neurological disorders that had a decrease in rates and absolute numbers of deaths and DALYs were tetanus, meningitis, and encephalitis. The four largest contributors of neurological DALYs were stroke (42·2% [38·6–46·1]), migraine (16·3% [11·7–20·8]), Alzheimer's and other dementias (10·4% [9·0–12·1]), and meningitis (7·9% [6·6–10·4]). For the combined neurological disorders, age-standardised DALY rates were significantly higher in males than in females (male-to-female ratio 1·12 [1·05–1·20]), but migraine, multiple sclerosis, and tension-type headache were more common and caused more burden in females, with male-to-female ratios of less than 0·7. The 84 risks quantified in GBD explain less than 10% of neurological disorder DALY burdens, except stroke, for which 88·8% (86·5–90·9) of DALYs are attributable to risk factors, and to a lesser extent Alzheimer's disease and other dementias (22·3% [11·8–35·1] of DALYs are risk attributable) and idiopathic epilepsy (14·1% [10·8–17·5] of DALYs are risk attributable). Interpretation: Globally, the burden of neurological disorders, as measured by the absolute number of DALYs, continues to increase. As populations are growing and ageing, and the prevalence of major disabling neurological disorders steeply increases with age, governments will face increasing demand for treatment, rehabilitation, and support services for neurological disorders. The scarcity of established modifiable risks for most of the neurological burden demonstrates that new knowledge is required to develop effective prevention and treatment strategies. Funding: Bill & Melinda Gates Foundation. © 2019 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
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- 2019
23. Do centrally obese Chinese with normal BMI have increased risk of metabolic disorders?
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Yeh, W-T, Chang, H-Y, Yeh, C-J, Tsai, K-S, Chen, H-J, and Pan, W-H
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- 2005
24. Microdialysis for measurement of hepatic and systemic nitric oxide biosynthesis in septic rats
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HUANG, C.-J., TSAI, P.-S., PAN, W. H. T., and SKIMMING, J. W.
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- 2005
25. NF-κB involvement in the induction of high affinity CAT-2 in lipopolysaccharide-stimulated rat lungs
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HUANG, C.-J., TSAI, P.-S., LU, Y.-T., CHENG, C.-R., STEVENS, B. R., SKIMMING, J. W., and PAN, W. H. T.
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- 2004
26. Prevalence and awareness of diabetes and mean fasting glucose by age, sex, and region: results from the Nutrition and Health Survey in Taiwan, 1993–1996
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Pan, W.-H., Yeh, W.-T., Chang, H.-Y., Hwu, C.-M., and Ho, L.-T.
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- 2003
27. Association between markers in chromosomal region 17q23 and young onset hypertension: a TDT study
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Wu, S-Y, Fann, C S J, Jou, Y-S, Chen, J-W, and Pan, W-H
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- 2002
28. Dietary factors associated with physician-diagnosed asthma and allergic rhinitis in teenagers: analyses of the first Nutrition and Health Survey in Taiwan
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Huang, S.-L., Lin, K.-C., and Pan, W.-H.
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- 2001
29. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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- Abstract
Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2·5th percentile and 100 as the 97·5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59·4 (IQR 35·4–67·3), ranging from a low of 11·6 (95% uncertainty interval 9·6–14·0) to a high of 84·9 (83·1–86·7). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030. Funding: Bill & Melinda Gates Foundation. © 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license
- Published
- 2018
30. Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: A pooled analysis of 1018 population-based measurement studies with 88.6 million participants
- Author
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Severino, Italy, Karolinska Institutet, Sweden, University of Porto, Portugal, Santiago de Compostela University, Spain, Associazione Calabrese di Epatologia, Italy, India Diabetes Research Foundation, India, Duke-NUS Medical School, Singapore, National Institute of Medical Statistics, India, Academia Sinica, Taiwan, Capital Institute of Pediatrics, China, Duke University, United States, Kailuan General Hospital, China, The Gertner Institute for Epidemiology and Health Policy Research, Israel, University of Bern, Switzerland, Ministry of Health and Welfare, Taiwan, Victor Babes University of Medicine and Pharmacy Timisoara, Romania, Murcia Regional Health Council, Spain, Seoul National University College of Medicine, South Korea, Korea Centers for Disease Control and Prevention, South Korea, Universidade Estadual Paulista, Brazil, Medical University of Silesia, Poland, Charles University in Prague, Czech Republic, Carol Davila University of Medicine and Pharmacy, Romania, Katholieke Universiteit Leuven, Belgium, Agency for Preventive and Social Medicine, Austria, University of Southampton, United Kingdom, IRCCS Istituto Neurologico Mediterraneo Neuromed, Italy, Institut Pasteur de Lille, France, CIBEROBN, Spain, National Council of Research, Italy, Universidade Federal de Santa Catarina, Brazil, Eduardo Mondlane University, Mozambique, Bispebjerg and Frederiksberg Hospital, Denmark, Lille University Hospital, France, Erasmus Medical Center Rotterdam, Netherlands, University of Montreal, Canada, French Public Health Agency, France, Universidade do Vale do Rio dos Sinos, Brazil, National Council of Scientific and Technical Research, Argentina, National Institute of Nutrition, Viet Nam, University of Queensland, Australia, Istituto Superiore di Sanità, Italy, Universidad de Cuenca, Ecuador, Helmholtz Zentrum München, Germany, Ministère de la Santé et de la Lutte Contre le Sida, Cote d'Ivoire, The Cardinal Wyszynski Institute of Cardiology, Poland, University of Latvia, Latvia, National Institute of Nutrition and Food Technology, Tunisia, Institut Hospital del Mar d'Investigacions Mèdiques, Spain, University of Stellenbosch, South Africa, Karadeniz Technical University, Turkey, National Institute for Health and Welfare, Finland, Queen's University of Belfast, United Kingdom, University of Zurich, Switzerland, Centro de Salud Villanueva Norte, Spain, The University of the West Indies, Jamaica, Hospital Don Benito-Villanueva de la Serena, Spain, Ministry of Health, Argentina, Council for Agricultural Research and Economics, Italy, Pontificia Universidad Católica de Chile, Chile, University of Manchester, United Kingdom, University of Tartu, Estonia, Universiti Sains Malaysia, Malaysia, Umeå University, Sweden, Dalarna University, Sweden, Federal University of São Paulo, Brazil, Hospital Universitario Son Espases, Spain, Hospital de Clinicas de Porto Alegre, Brazil, Universidade Federal do Rio Grande do Sul, Brazil, Kindai University, Japan, Kyoto University, Japan, Medical University of Warsaw, Poland, University of Catania, Italy, CIBER en Epidemiología y Salud Pública, Spain, University of KwaZulu-Natal, South Africa, Geneva University Hospitals, Switzerland, Australian Bureau of Statistics, Australia, Wageningen University, Netherlands, B P Koirala Institute of Health Sciences, Nepal, University of Insubria, Italy, Ministry of Health, Israel, The Andes Clinic of Cardio-Metabolic Studies, Venezuela, National Institute of Hygiene, Epidemiology and Microbiology, Cuba, Université de Lille 2, France, Institute for Clinical and Experimental Medicine, Czech Republic, Children'sMemorial Health Institute, Poland, Alexander Technological Educational Institute, Greece, Jagiellonian University Medical College, Poland, Azienda Ospedaliera Universitaria Policlinico Vittorio Emanuele, Italy, University of Novi Sad, Serbia, National Center of Cardiovascular Diseases, China, Singapore Eye Research Institute, Singapore, Icelandic Heart Association, Iceland, Universidad Icesi, Colombia, King's College London, United Kingdom, International Agency for Research on Cancer, France, Healis-Sekhsaria Institute for Public Health, India, Eternal Heart Care Centre and Research Institute, India, University of Ibadan, Nigeria, Children's Memorial Health Institute, Poland, Institute for Clinical Effectiveness and Health Policy, Argentina, Danish Cancer Society Research Centre, Denmark, Kyushu University, Japan, Tulane University, United States, Chinese Center for Disease Control and Prevention, China, Academic Medical Center of University of Amsterdam, Netherlands, National Institute of Public Health, Mexico, Oulu University Hospital, Finland, Chronic Diseases Research Center, Iran, University of Hong Kong, Hong Kong, The Chinese University of Hong Kong, Hong Kong, University of Western Australia, Australia, Celal Bayar University, Turkey, Heart Institute, Brazil, Fundación Oftalmológica de Santander, Colombia, University of Oran 1, Algeria, Independent Public Health Specialist, Myanmar, Ministry of Health, Myanmar, Peking University, China, VU University Medical Center and VU University, Netherlands, American University of Beirut, Lebanon, Cairo University, Egypt, National Institute of Health and Nutrition, Japan, Aga Khan University, Pakistan, UHC Zagreb, Croatia, Niigata University, Japan, Hadassah University Medical Center, Israel, Duke- NUS Medical School, Singapore, Norwegian University of Science and Technology, Norway, University of Zagreb School of Medicine, Croatia, Heart Foundation, Australia, National Health Insurance Service, South Korea, Guangzhou 12th Hospital, China, Simon Fraser University, Canada, Ruprecht-Karls- University of Heidelberg, Germany, Research Centre for Prevention and Health, Denmark, World Health Organization Country Office, India, Czestochowa University of Technology, Poland, University of Crete, Greece, Universiti Kebangsaan Malaysia, Malaysia, Johns Hopkins Bloomberg School of Public Health, United States, University of Eastern Finland, Finland, National Institute of Epidemiology, India, University of Münster, Germany, Israel Center for Disease Control, Israel, Research Institute for Primordial Prevention of Noncommunicable Disease, Iran, VU University Medical Center, Netherlands, Kyrgyz State Medical Academy, Kyrgyzstan, Research Institute of Child Nutrition, Germany, University of Cambridge, United Kingdom, Medical University of Innsbruck, Austria, Muhimbili University of Health and Allied Sciences, Tanzania, National Cancer Center, South Korea, Institute of Tropical Medicine, Belgium, Tartu University Clinics, Estonia, Ministry of Health and Quality of Life, Mauritius, Polish Academy of Sciences Anthropology Unit in Wroclaw, Poland, University of Zürich, Switzerland, University of Groningen, Netherlands, North-West University, South Africa, National Institute of Public Health, Czech Republic, University of Jyväskylä, Finland, Amrita Institute of Medical Sciences, India, All India Institute of Medical Sciences, India, African Population and Health Research Center, Kenya, Ministerio de Salud Pública, Cuba, Sahlgrenska Academy, Sweden, Endocrinology and Metabolism Research Center, Iran, Food and Agriculture Organization of the United Nations, Italy, National University of Singapore, Singapore, Tampere University Hospital, Finland, University of Cape Town, South Africa, West Virginia University, United States, Oswaldo Cruz Foundation Rene Rachou Research Institute, Brazil, National Taiwan University, Taiwan, University of Chinese Academy of Sciences, China, University Medicine Greifswald, Germany, Consejería de Sanidad Junta de Castilla y León, Spain, University of Uppsala, Sweden, Universidade Federal de Ouro Preto, Brazil, The Jikei University School of Medicine, Japan, National Research Council, Italy, Baker Heart and Diabetes Institute, Australia, Agricultural University of Athens, Greece, Hospital Israelita Albert Einstein, Brazil, Shiraz University of Medical Sciences, Iran, Institute of Internal and Preventive Medicine, Russian Federation, Harokopio University, Greece, University of Otago, New Zealand, University of Padova, Italy, Lausanne University Hospital, Switzerland, CIBERCV, Spain, Emory University, United States, UiT The Arctic University of Norway, Norway, Cape Peninsula University of Technology, South Africa, Gorgas Memorial Institute of Health Studies, Panama, Brown University, United States, University of Edinburgh, United Kingdom, Statistics Canada, Canada, University College Dublin, Ireland, Institut National de la Santé et de la Recherche Médicale, France, Lusófona University, Portugal, Universita' degli Studi di Firenze, Italy, Ain Shams University, Egypt, Hypertension Research Center, Iran, University of Pécs, Hungary, Seoul National University Children's Hospital, South Korea, University Medical Science, Cuba, Universidad de Zaragoza, Spain, RCSI Dublin, Ireland, La Trobe University, Australia, International Institute of Molecular and Cell Biology, Poland, Ahvaz Jundishapur University of Medical Sciences, Iran, Gorgas Memorial Institute of Public Health, Panama, World Health Organization Country Office, Malawi, Department of Public Health, Myanmar, University of Brescia, Italy, Bushehr University of Medical Sciences, Iran, Ulm University, Germany, Kobe University, Japan, Suraj Eye Institute, India, University Medicine of Greifswald, Germany, INSERM, France, National Institute of Hygiene and Epidemiology, Viet Nam, The University of Pharmacy and Medicine of Ho Chi Minh City, Viet Nam, Hanoi Medical University, Viet Nam, National Hospital of Endocrinology, Viet Nam, Miami Veterans Affairs Healthcare System, United States, University of Turku Tyks, Finland, Heartfile, Pakistan, Eastern Mediterranean Public Health Network, Jordan, Tachikawa General Hospital, Japan, Academic Hospital of Paramaribo, Suriname, Ministry of Health, Brunei Darussalam, University of Madeira, Portugal, MRC Lifecourse Epidemiology Unit, United Kingdom, Aarhus University, Denmark, Kwame Nkrumah University of Science and Technology, Ghana, Institute for Social and Preventive Medicine, Switzerland, University of Coimbra, Portugal, Cancer Prevention and Research Institute, Italy, Ruprecht-Karls-University of Heidelberg, Germany, IRCCS Casa Sollievo della Sofferenza, Italy, Zayed University, United Arab Emirates, Catholic University of Daegu, South Korea, Jivandeep Hospital, India, University Hospital Centre Zagreb, Croatia, University Medical Center Utrecht, Netherlands, Vietnam National Heart Institute, Viet Nam, University of Sarajevo, Bosnia and Herzegovina, Cardiovascular Prevention Centre Udine, Italy, Ministry of Health and Medical Services, Solomon Islands, Public Health Agency of Catalonia, Spain, University of Split, Croatia, Digestive Oncology Research Center, Iran, Digestive Disease Research Institute, Iran, Alborz University of Medical Sciences, Iran, Ministry of Health, Viet Nam, University of Turku, Finland, Universiti Putra Malaysia, Malaysia, University of Malaya, Malaysia, University of Valencia, Spain, University of the Philippines, Philippines, Minas Gerais State Secretariat for Health, Brazil, Health Center San Agustín, Spain, PharmAccess Foundation, Netherlands, Universidade Nove de Julho, Brazil, Public Health Agency of Canada, Canada, Canarian Health Service, Spain, Universidad Industrial de Santander, Colombia, Instituto Nacional de Salud Pública, Mexico, Sitaram Bhartia Institute of Science and Research, India, Marmara University, Turkey, CIBER de Epidemiología y Salud Pública, Spain, University of Helsinki, Finland, National Institute of Health, Peru, Catalan Department of Health, Spain, Universidade de Lisboa, Portugal, University of Sao Paulo Clinics Hospital, Brazil, South Karelia Social and Health Care District, Finland, Isfahan Cardiovascular Research Center, Iran, Research and Education Institute of Child Health, Cyprus, Hospital Italiano de Buenos Aires, Argentina, Lagos State University College of Medicine, Nigeria, The University of Tokyo, Japan, Samsung Medical Center, South Korea, Federal University of Santa Catarina, Brazil, St Vincent's Hospital, Australia, Academic Medical Center Amsterdam, Netherlands, University of Bari, Italy, Lund University, Sweden, University of Copenhagen, Denmark, Institut Régional de Santé Publique, Benin, University of Bordeaux, France, University of Leuven, Belgium, Bonn University, Germany, Sotiria Hospital, Greece, National Institute of Public Health- National Institute of Hygiene, Poland, Fu Jen Catholic University, Taiwan, Ministry of Health, Jordan, Health Service of Murcia, Spain, IB-SALUT Area de Salut de Menorca, Spain, Institut de Recherche pour le Développement, France, Hellenic Health Foundation, Greece, GovernmentMedical College, India, Sefako Makgatho Health Science University, South Africa, Addis Ababa University, Ethiopia, Dasman Diabetes Institute, Kuwait, Ministry of Health, New Zealand, Universidad Centro-Occidental Lisandro Alvarado, Venezuela, University of Tampere Tays Eye Center, Finland, Utrecht University, Netherlands, Hanoi University of Public Health, Viet Nam, Amsterdam Public Health Research Institute, Netherlands, Universidade Federal de Minas Gerais, Brazil, Finnish Institute of Occupational Health, Finland, Universidad Miguel Hernandez, Spain, North Karelian Center for Public Health, Finland, University of the Witwatersrand, South Africa, University of Strasbourg, France, Institute for Medical Research, Malaysia, Xinjiang Medical University, China, Capital Medical University, China, St George's, University of London, United Kingdom, Medical University of Vienna, Austria, Universitas Indonesia, Indonesia, National Institute of Public Health-National Institute of Hygiene, Poland, Institute of Food and Nutrition Development of Ministry of Agriculture, China, Children's Hospital of Fudan University, China, University of Cyprus, Cyprus, Universiti Teknologi MARA, Malaysia, Inner Mongolia Medical University, China, Universidad Politécnica de Madrid, Spain, State University of Montes Claros, Brazil, and University of Limpopo, South Africa
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sense organs - Abstract
Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). Our aim was to quantify the contributions of these two phenomena to the worldwide trends in the prevalence of raised blood pressure. Methods: We pooled 1018 population-based studies with blood pressure measurements on 88.6 million participants from 1985 to 2016. We first calculated mean systolic blood pressure (SBP), mean diastolic blood pressure (DBP) and prevalence of raised blood pressure by sex and 10-year age group from 20-29 years to 70-79 years in each study, taking into account complex survey design and survey sample weights, where relevant. We used a linear mixed effect model to quantify the association between (probittransformed) prevalence of raised blood pressure and age-group- and sex-specific mean blood pressure. We calculated the contributions of change in mean SBP and DBP, and of change in the prevalence-mean association, to the change in prevalence of raised blood pressure. Results: In 2005-16, at the same level of population mean SBP and DBP, men and women in South Asia and in Central Asia, the Middle East and North Africa would have the highest prevalence of raised blood pressure, and men and women in the highincome Asia Pacific and high-income Western regions would have the lowest. In most region-sex-age groups where the prevalence of raised blood pressure declined, one half or more of the decline was due to the decline in mean blood pressure. Where prevalence of raised blood pressure has increased, the change was entirely driven by increasing mean blood pressure, offset partly by the change in the prevalence-mean association. Conclusions: Change in mean blood pressure is the main driver of the worldwide change in the prevalence of raised blood pressure, but change in the high-blood-pressure tail of the distribution has also contributed to the change in prevalence, especially in older age groups. © The Author(s) 2018.
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- 2018
31. Matrix Method for Buckling Analysis of Frames Based on Hencky Bar-Chain Model
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Pan, W. H., primary, Wang, C. M., additional, and Zhang, H., additional
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- 2019
- Full Text
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32. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.
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Servan-Mori E., Usman M.S., Uthman O.A., Vaduganathan M., Vaezi A., Vaidya G., Valdez P.R., Van Donkelaar A., Varavikova E., Vasankari T.J., Venketasubramanian N., Vidavalur R., Villafaina S., Violante F.S., Vladimirov S.K., Vlassov V., Vollmer S., Vollset S.E., Vos T., Vosoughi K., Vujcic I.S., Wagner G.R., Wagnew F.S., Waheed Y., Walson J.L., Wang Y., Wang Y.-P., Wassie M.M., Weiderpass E., Weintraub R.G., Weiss J., Weldegebreal F., Weldegwergs K.G., Werdecker A., Werkneh A.A., West T.E., Westerman R., Whisnant J.L., Whiteford H.A., Widecka J., Widecka K., Wijeratne T., Wilner L.B., Winkler A.S., Wiyeh A.B., Wiysonge C.S., Wolde H.F., Wolfe C.D.A., Wu S., Xavier D., Xu G., Xu R., Yadollahpour A., Jabbari S.H.Y., Yakob B., Yamada T., Yan L.L., Yano Y., Yaseri M., Yasin Y.J., Ye P., Yearwood J.A., Yeshaneh A., Yimer E.M., Yip P., Yirsaw B.D., Yisma E., Yonemoto N., Yonga G., Yoon S.-J., Yotebieng M., Younis M.Z., Yousefifard M., Yu C., Zaman S.B., Zamani M., Zare Z., Zavala-Arciniega 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J.R., Lee J.B., Lee P.H., Leever A.T., Leigh J., Leinsalu M., Leshargie C.T., Leung J., Lewycka S., Li S., Li X., Li Y., Liang J., Liang X., Liben M.L., Lim L.-L., Limenih M.A., Linn S., Liu S., Liu Y., Lodha R., Logroscino G., Lopez A.D., Lorkowski S., Lotufo P.A., Lucchesi L.R., Lyons R.A., Macarayan E.R.K., Mackay M.T., Maddison E.R., Madotto F., Maghavani D.P., Magis-Rodriguez C., Mahotra N.B., Majdan M., Majdzadeh R., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manda A.-L., Mandarano-Filho L.G., Mangalam S., Manguerra H., Mansournia M.A., Mapoma C.C., Maravilla J.C., Marcenes W., Marks A., Martin R.V., Martins S.C.O., Martins-Melo F.R., Martopullo I., Mashamba-Thompson T.P., Massenburg B.B., Mathur M.R., Maulik P.K., Mazidi M., McAlinden C., McGrath J.J., McKee M., McMahon B.J., Mehata S., Mehndiratta M.M., Mehrotra R., Mehta K.M., Mehta V., Mejia-Rodriguez F., Mekonen T., Mekonnen T.C.C., Meles H.G., Melese A., Melku M., Memiah P.T.N., Memish Z.A., Mendoza W., Mengistu 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Roth G.A., Roy A., Rubagotti E., Ruhago G.M., Sabde Y.D., Sachdev P.S., Saddik B., Sadeghi E., Safari H., Safari Y., Safari-Faramani R., Safdarian M., Safi S., Safiri S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi H.S., Salam N., Salama J.S., Salamati P., De Freitas Saldanha R., Saleem Z., Salimi Y., Salimzadeh H., Salomon J.A., Salvi S.S., Salz I., Sambala E.Z., Samy A.M., Sanabria J., Sanchez-Nino M.D., Santos I.S., Milicevic M.M.S., Jose B.P.S., Sardana M., Sarker A.R., Sarrafzadegan N., Sartorius B., Sarvi S., Sathian B., Satpathy M., Savic M., Sawant A.R., Sawhney M., Saxena S., Saylan M., Sayyah M., Schaeffner E., Schmidt M.I., Schneider I.J.C., Schottker B., Schutte A.E., Schwebel D.C., Schwendicke F., Seedat S., Sekerija M., Sepanlou S.G., Seyedmousavi S., Shabaninejad H., Shackelford K.A., Shafieesabet A., Shaheen A.A., Shaikh M.A., Shams-Beyranvand M., Shamsi M.B., Shamsizadeh M., Sharafi H., Sharafi K., Sharif M., Sharif-Alhoseini M., Sharma J., Sharma R., Sharma S.K., She 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Tanser F.C., Tassew A.A., Tassew S.G., Tavakkoli M., Taveira N., Tawye N.Y., Tehrani-Banihashemi A., Tekalign T.G., Tekle M.G., Temesgen H., Temsah M.-H., Temsah O., Terkawi A.S., Teshale M.Y., Teshome D.F., Tessema B., Teweldemedhin M., Thakur J.S., Thankappan K.R., Theis A., Thirunavukkarasu S., Thomas L.A., Thomas N., Thomson A.J., Tilahun B., To Q.G., Tobe-Gai R., Tonelli M., Topor-Madry R., Torre A.E., Tortajada-Girbes M., Tovani-Palone M.R., Towbin J.A., Tran B.X., Tran K.B., Tran T.T., Tripathy S.P., Troeger C.E., Truelsen T.C., Tsadik A.G., Car L.T., Tuzcu E.M., Tymeson H.D., Ukwaja K.N., Ullah I., and Updike R.L.
- Abstract
Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. Method(s): We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2.5th percentile and 100 as the 97.5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the prob
- Published
- 2018
33. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults
- Author
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SDG 3 - Good Health and Well-being ,Medicine (all) - Abstract
Made available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16 Wellcome Trust AstraZeneca Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based studies with measurements of height and weight on 128.9 million participants aged 5 years and older, including 31.5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Findings Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0.01 kg/m (2) per decade; 95% credible interval -0.42 to 0.39, posterior probability [PP] of the observed decrease being a true decrease= 0.5098) in eastern Europe to an increase of 1.00 kg/m(2) per decade (0.69-1.35, PP> 0.9999) in central Latin America and an increase of 0.95 kg/m (2) per decade (0.64-1.25, PP> 0.9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0.09 kg/m(2) per decade (-0.33 to 0.49, PP= 0.6926) in eastern Europe to an increase of 0.77 kg/m (2) per decade (0.50-1.06, PP> 0.9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0.7% (0.4-1.2) in 1975 to 5.6% (4.8-6.5) in 2016 in girls, and from 0.9% (0.5-1.3) in 1975 to 7.8% (6.7-9.1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9.2% (6.0-12.9) in 1975 to 8.4% (6.8-10.1) in 2016 in girls and from 14.8% (10.4-19.5) in 1975 to 12.4% (10.3-14.5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22.7% (16.7-29.6) among girls and 30.7% (23.5-38.0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. Interpretation The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. Imperial Coll London, Sch Publ Hlth, London W2 1PG, England Univ Kent, Canterbury, Kent, England Imperial College London, London, England Middlesex Univ, London, England WHO, Geneva, Switzerland Cleveland Clin, Cleveland, OH 44106 USA Yale Univ, New Haven, CT 06520 USA Univ Calif Berkeley, Berkeley, CA USA Victor Babes Univ Med & Pharm Timisoara, Timisoara, Romania Univ Sydney, Sydney, NSW, Australia Johns Hopkins Univ, Baltimore, MD 21218 USA Isfahan Univ Med Sci, Esfahan, Iran South African Med Res Council, Cape Town, South Africa Seoul Natl Univ, Seoul, South Korea Natl Inst Nutr, Secunderabad, India Harvard TH Chan Sch Publ Hlth, Boston, MA USA Peking Univ, Beijing, Peoples R China Univ Peruana Cayetano Heredia, Lima, Peru Ain Shams Univ, Cairo, Egypt Karolinska Inst, Stockholm, Sweden Univ Coimbra, Coimbra, Portugal Univ Putra Malasia, Seri Kembangan, Malaysia Hosp Sick Children, Toronto, ON, Canada Aga Khan Univ, Karachi, Pakistan Caja Costarricense Seguro Social, San Jose, Costa Rica Al Quds Univ, Jerusalem, Palestine Ctr Diabet & Endocrine Care, Bengaluru, India Birzeit Univ, Birzeit, Palestine Inst Mexicano Seguro Social, Mexico City, DF, Mexico Int Rice Res Inst, Los Banos, Philippines Univ Adelaide, Adelaide, SA, Australia Mahidol Univ, Salaya, Nakhon Pathom, Thailand BARC, Dhaka, Bangladesh Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico City, DF, Mexico Univ Amsterdam, Amsterdam, Netherlands Noncommun Dis Res Ctr, Tehran, Iran Leibniz Inst Prevent Res & Epidemiol BIPS, Leipzig, Germany Natl Ctr Diabet Endocrinol, Amman, Jordan Kazakh Natl Med Univ, Alma Ata, Kazakhstan King Saud Univ, Riyadh, Saudi Arabia Kuwait Inst Sci Res, Kuwait, Kuwait Minist Hlth, Riyadh, Saudi Arabia King Abdullah Int Med Res Ctr, Riyadh, Saudi Arabia Univ Malaysia Sabah, Kota Kinabalu, Malaysia Luxembourg Inst Hlth, Luxembourg, Luxembourg ISGlobal Ctr Res Environm Epidemol, Barcelona, Spain WHO, Reg Off Eastern Mediterranean, Cairo, Egypt Bombay Hosp & Med Res Ctr, Bombay, Maharashtra, India Lille Univ & Hosp, Lille, France London Sch Hyg & Trop Med, London, England Western Norway Univ App Sci, Bergen, Norway Norwegian Sch Sport Sci, Oslo, Norway Univ Cuenca, Cuenca, Ecuador Bispebjerg Hosp, Copenhagen, Denmark Frederiksberg Univ Hosp, Copenhagen, Denmark Madras Diabet Res Fdn, Madras, Tamil Nadu, India Natl Inst Publ Hlth, Tunis, Tunisia Univ Porto, Oporto, Portugal Norwegian Inst Publ Hlth, Oslo, Norway Minist Hlth Malaysia, Putrajaya, Malaysia Natl Inst Nutr, Bangalore, Karnataka, India Univ Strasbourg, Strasbourg, France Strasbourg Univ Hosp, Strasbourg, France Nepal Hlth Res Council, Kathmandu, Nepal Univ Iceland, Reykjavik, Iceland Univ Yaounde, Yaounde, Cameroon Univ Fed Pelotas, Pelotas, Brazil Univ Med, Yangon, Myanmar Univ Porto, Med Sch, Oporto, Portugal Shahid Beheshti Univ Med Sci, Tehran, Iran Indian Council Med Res, New Delhi, India King Abdulaziz Univ, Riyadh, Saudi Arabia Univ Sci & Technol, Taizi, Yemen Med Univ Lodz, Lodz, Poland Med Univ Gdansk, Gdansk, Poland Univ Autonoma Madrid, Madrid, Spain Univ Palermo, Palermo, Italy Pan Amer Hlth Org, Washington, DC USA Mohammed V Univ Rabat, Rabat, Morocco Univ Pernambuco, Recife, PE, Brazil Dalhousie Univ, Calgary, AB, Canada Jordan Univ Technol, Amman, Jordan Univ Fed Maranhao, Sao Luis, Brazil Univ Auckland, Auckland, New Zealand Univ Tunis El Manar, El Manar, Tunisia Fed Minist Hlth & Womens Affairs, Vienna, Austria CAFAM Univ Fdn, Bogota, Colombia Imperial Coll London, London, England Lithuanian Univ Hlth Sci, Kaunas, Lithuania Univ Sao Paulo, Sao Paulo, Brazil BJ Med Coll, Pune, Maharashtra, India Chirayu Med Coll, Bhopal, India Sunder Lal Jain Hosp, Delhi, India Shandong Univ Tradit Chinese Med, Shanghai, Peoples R China Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China Norwegian Inst Publ, Oslo, Norway Ufa Eye Res Inst, Moscow, Russia Univ Montenegro, Montenegro, Mexico Univ Southern Denmark, Lyngby, Denmark Univ Oslo, Oslo, Norway Univ Gothenburg, 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Technol, Cork, Ireland Univ La Laguna, San Cristobal la Laguna, Spain Univ Malta, Msida, Malta Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA Minist Hlth, Pangai, Tonga Canadian Fitness & Lifestyle Res Inst, Ottawa, ON, Canada Hosp Santa Maria, Lisbon, Portugal Istanbul Univ, Istanbul, Turkey Univ Fed Juiz de Fora, Juiz De Fora, Portugal Food & Nutr Res Inst, Manila, Philippines Santiago de Compostela Univ, Santiago De Compostela, Spain Assoc Calabrese Epatol, Perugia, Italy India Diabet Res Fdn, Delhi, India Duke NUS Med Sch, Singapore, Singapore Natl Inst Med Stat, New Delhi, India Acad Sinica, Taipei, Taiwan Capital Inst Pediat, Beijing, Peoples R China Duke Univ, Durham, NC 27706 USA Kailuan General Hospital, Tangshan, Peoples R China Univ Oxford, Oxford, England Duke NUS MEd Sch, Singapore, Singapore Gertner Inst Epidemiol & Hlth Policy Res, Tel Aviv, Israel Natl Ctr Publ Hlth & Anal, Sofia, Bulgaria Univ Bern, Bern, Switzerland Minist Hlth & Welfare, Taipei, Taiwan Murcia Reg Hlth Council, Murcia, Spain Seoul Natl Univ, Coll Med, Seoul, South Korea Korea Ctr Dis Control & Prevent, Seoul, South Korea Univ Estadual Paulista, Sao Paulo, Brazil Med Univ Silesia, Katowice, Poland Charles Univ Prague, Prague, Czech Republic Katholieke Univ Leuven, Leuven, Belgium Agcy Prevent & Social Med, Vienna, Austria Univ Fed Santa Catarina, Sao Carlos, SP, Brazil Univ Southampton, Southampton, Hants, England Inst Pasteur, Lille, France CIBEROBN, Barcelona, Spain Natl Inst Publ Hlth, Bucharest, Romania Natl Council Res, Rome, Italy Univ Fed Santa Catarin, Sao Carlos, SP, Brazil Eduardo Mondlane Univ, Maputo, Mozambique Univ Copenhagen, Copenhagen, Denmark Res Ctr Prevent & Hlth, Glostrup, Denmark Tabriz Hlth Serv Managemnet Ctr, Tabriz, Iran Lille Univ Hosp, Lille, France Sci Inst Publ Hlth, Brussels, Belgium Madaras Diabet Res Fdn, Chennai, India Natl Res Ctr Prevent Med, Moscow, Russia Erasmus MC, Rotterdam, Netherlands Univ Montreal, Montreal, PQ, Canada Inst Rech Dev, Montpellier, France French Publ Hlth Agcy, St Maurice, France Univ Vale Rio Sino, Sao Leopoldo, Brazil Natl Council Sci & Tech Res, Buenos Aires, DF, Argentina Univ Zagreb, Zagreb, Croatia Univ Tehran Med Sci, Tehran, Iran Natl Inst Nutr, Hanoi, Vietnam Univ Queensland, Brisbane, Qld, Australia Ist Super Sanita, Rome, Italy Helmholtz Zentrum Munchen, Munich, Germany Minist Sante & Lutte Contre Sida, Abidjan, Cote Ivoire Cardinal Wyszynski Inst Cardiol, Warsaw, Poland Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China Univ Latvia, Riga, Latvia Univ Benin, Benin, Nigeria Univ Skovde, Skovde, Sweden Natl Inst Nutr & Food Technol, Tunis, Tunisia Univ Calif Davis, Davis, CA 95616 USA Univ Stellenbosch, Stellenbosch, South Africa Karadeniz Tech Univ, Trabzon, Turkey Univ Southern Copenhagen, Copenhagen, Denmark Natl Inst Hlth & Welfare, Helsinki, Finland Queens Univ Belfast, Belfast, Antrim, North Ireland Univ Zurich, Zurich, Switzerland Primary Health Care, Floriana, Malta Ctr Salud Villanueva Norte, Villanueva De La Serena, Spain Univ West Indies, Mona, Jamaica Hosp Don Benito Villanueva de la Serena, Villanueva De La Serena, Spain Minist Hlth, Buenos Aires, DF, Argentina Council Agr Res & Econ, Rome, Italy Pontificia Univ Catolica Chile, Santiago, Chile Univ Toulouse, Sch Med, Toulouse, France Univ Manchester, Manchester, Lancs, England Univ Tartu, Tartu, Estonia Inst Nacl Salud Publ, Cuernavaca, Morelos, Mexico Univ Sains Malaysia, George Town, Malaysia Umea Univ, Umea, Sweden Dalarna University, Falun, Sweden Univ West Indies, Kingston, Jamaica Univ Fed Sao Paulo, Sao Paulo, Brazil Hosp Univ Son Espases, Palma De Mallorca, Spain Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil Univ Fed Rio Grande do Sul, Rio Grande, Brazil Kindai Univ, Higashiosaka, Osaka, Japan Kyoto Univ, Kyoto, Japan Med Univ Warsaw, Warsaw, Poland Minist Hlth, Rome, Italy Univ Catania, Catania, Italy CIBER Epidemiol & Salud Publ, Barcelona, Spain Univ KwaZulu Natal, Durban, South Africa Geneva Univ Hosp, Geneva, Switzerland Australian Bur Stat, Canberra, ACT, Australia Agcy Prevent & Social Med, Innsbruck, Austria Wageningen Univ, Wageningen, Netherlands Noncommunicable Dis Res Ctr, Shiraz, Iran Univ Insubria, Varese, Italy Lund Univ, Lund, Sweden Minist Hlth, Ankara, Turkey Minist Hlth, Jerusalem, Israel McGill Univ, Montreal, PQ, Canada Andes Clin Cardiometab Studies, Timotes, Venezuela Univ Politecn Madrid, Madrid, Spain Univ Lille 2, Lille, France Minist Hlth, Lisbon, Portugal Inst Clin & Expt Med, Prague, Czech Republic Childrens Mem Hlth Inst, Warsaw, Poland Alexander Technol Educ Inst, Sindos, Greece Dalhousie Univ, Halifax, NS, Canada Jagiellonian Univ, Med Coll, Krakow, Poland Univ Southern Denmark, Odense, Denmark Azienda Osped Univ Policlin Vittorio Emanuele, Catania, Italy Univ Novi Sad, Novi Sad, Serbia Natl Ctr Cardiovasc Dis, Beijing, Peoples R China Univ Ferrara, Ferrara, Italy Singapore Eye Res Inst, Singapore, Singapore Iceland Heart Assoc, Kopavogur, Iceland Univ Icesi, Cali, Colombia Univ Estadual Montes Claros, Montes Claros, Brazil Kings Coll London, London, England Int Agcy Res Canc, Lyon, France Capital Med Univ, Beijing, Peoples R China Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, India Eternal Heart Care Ctr Res Inst, Jaipur, Rajasthan, India Univ Ibadan, Ibadan, Nigeria Childrens Memorial Hlth Inst, Warsaw, Poland Inst Clin Effectiveness & Hlth Policy, Buenos Aires, DF, Argentina Res & Educ Inst Child Hlth, Nicosia, Cyprus Minist Hlth, Seri Begawan, Brunei Danish Canc Soc, Res Ctr, Copenhagen, Denmark Univ West Indies, Bridgetown, Barbados Alexander Technol Educ Inst Thessaloniki, Sindos, Greece Kyushu Univ, Fukuoka, Japan Tulane Univ, New Orleans, LA 70118 USA Univ Pecs, Pecs, Hungary Univ Coll Dublin, Dublin, Ireland Univ Amsterdam, Acad Med Ctr, Amsterdam, Netherlands Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico Oulu Univ Hosp, SF-90100 Oulu, Finland Univ Autonoma Bucaramanga, Bucaramanga, Colombia Swiss Fed Inst Technol, Zurich, Switzerland Chron Diseases Res Ctr, Tehran, Iran Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China Univ Western Australia, Perth, WA, Australia Kingston Gen Hosp, Kingston, ON, Canada Heart Inst, Sao Paulo, Brazil Fdn Oftalmol Santander, Floridablanca, Colombia Univ Oran 1, Oran, Algeria Minist Hlth, Naypyitaw, Myanmar Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands Vrije Univ Amsterdam, Amsterdam, Netherlands Amer Univ Beirut, Beirut, Lebanon IRCCS Ist Neurol Mediterraneo Neuromed, Pozzilli, Italy Cardiol Mercato S Severino, Mercato San Severino, Italy Cairo Univ, Giza, Egypt Natl Inst Hlth & Nutr, Tokyo, Japan UHC Zagreb, Zagreb, Croatia Niigata Univ, Niigata, Japan Hadassah Univ, Med Ctr, Jerusalem, Israel Jordan Univ Sci & Technol, Irbid, Jordan Norwegian Univ Sci & Technol, Trondheim, Norway Sports Univ Tirana, Tirana, Albania Univ Zagreb, Sch Med, Zagreb, Croatia Heart Fdn, 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Cambridge, Cambridge, England Med Univ Innsbruck, Innsbruck, Austria Muhimbili Univ Hlth & Allied Sci, Dar Es Salaam, Tanzania Natl Canc Ctr, Goyang Si, South Korea Natl Hlh Insurance Serv, Seoul, South Korea Stat Austria, Vienna, Austria BP Koirala Inst Hlth Sci, Dharan, Nepal Inst Trop Med, Antwerp, Belgium Tartu Univ Clin, Tartu, Estonia Natl Inst Pharm & Nutr, Budapest, Hungary Minis Hlth & Qual Life, Port Louis, Mauritius Polish Acad Sci, Anthropol Unit Wroclaw, Wroclaw, Poland Univ Hosp Ulm, Ulm, Germany Univ Groningen, Groningen, Netherlands North West Univ, Potchefstroom, South Africa Natl Inst Publ Hlth, Prague, Czech Republic Univ Jyvaskyla, Jyvaskyla, Finland Amrita Inst Med Sci, Thiruvananthapuram, Kerala, India Inst Endocrinol, Prague, Czech Republic All India Inst Med Sci, New Delhi, India African Populat & Hlth Res Ctr, Nairobi, Kenya Hanoi Univ Publ Hlth, Hanoi, Vietnam Higher Inst Nursing Profess & Tech Hlth Morocco, Rabat, Morocco Natl Inst Publ Hlth Algeria, Algiers, Algeria Minist Salud Publ, Havana, Cuba Sahlgrens Acad, Gothenburg, Sweden Endocrinol & Met Res Ctr, Arak, Iran Indicium Res, Manila, Philippines Food & Agr Org, Rome, Italy Natl Univ Singapore, Singapore, Singapore Tampere Univ Hosp, Tampere, Finland Univ Cape Town, Cape Town, South Africa West Virginia Univ, Morgantown, WV USA Fundacao Oswaldo Cruz, Rene Rachou Res Inst, Belo Horizonte, MG, Brazil Natl Taiwan Univ, Taipei, Taiwan Univ Chinese Acad Sci, Beijing, Peoples R China Uppsala Univ, Uppsala, Sweden Capital Med Univ, Beijing An Zhen Hosp, Beijing, Peoples R China Natl Inst Hlth Dev, Tallinn, Estonia Univ Med Greifswald, Greifswald, Germany Consejeria Sanidad Junta Castilla & Leon, Valladolid, Spain Univ Fed Ouro Pret, Ouro Preto, Brazil Jikei Univ, Sch Med, Tokyo, Japan CNR, Rome, Italy Baker Heart & Diabet Inst, Melbourne, Vic, Australia Agr Univ Athens, Athens, Greece Univ Putra Malaysia, Seri Kembangan, Malaysia Inst Rech Dev, Marseille, France Hosp Israelita Albert Einstein, Sao Paulo, Brazil Shiraz Univ Med Sci, Shiraz, Iran Inst Internal & Prevent Med, Novosibirsk, Russia Harokopio Univ, Kallithea, Greece Univ Otago, Dunedin, New Zealand Univ Padua, Padua, Italy Technol Educ Inst Crete, Iraklion, Greece Loughborough Univ Technol, Loughborough, Leics, England Univ Fed Santa Catarina, Florianopolis, SC, Brazil Lausanne Univ Hosp, Lausanne, Switzerland Inst Hosp Mard Invest Med, Barcelona, Spain Mary Immaculate Coll, Limerick, Ireland Emory Univ, Atlanta, GA 30322 USA Hungarian Soc Sports Med, Budapest, Hungary Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India UiT Arctic Univ Norway, Tromso, Norway Cape Peninsula Univ Technol, Cape Town, South Africa Univ Rzeszow, Rzeszow, Poland Univ Yaounde I, Yaounde, Cameroon Brown Univ, Providence, RI 02912 USA Univ Edinburgh, Edinburgh, Midlothian, Scotland Stat Canada, Ottawa, ON, Canada Int Med Univ, Kuala Lumpur, Malaysia INSERM, Villejuif, France Helmholtz Zentrum Munchen, Oberschleissheim, Germany Robert Koch Inst, Berlin, Germany Lusofona Univ, Lisbon, Portugal Democritus Univ Greece, Komotini, Greece Grigore T Popa Univ Med & Pharm, Iasi, Romania Univ Firenze, Florence, Italy Hypertens Res Ctr, Esfahan, Iran Mulago Hosp, Kampala, Uganda Univ Limpopo, Polokwane, South Africa Seoul Natl Univ, Childrens Hosp, Seoul, South Korea Univ Fed Rio Grande do Sul, Porto Alegre, RS, Brazil Univ Med Sci, Havana, Cuba Univ Zaragoza, Zaragoza, Spain R CSI Dublin, Dublin, Ireland Int Inst Mol & Cell Biol, Warsaw, Poland Ain Shams University, Cairo, Egypt Ahvaz Jundishapur Univ Med Sci, Ahwaz, Iran Gorgas Memorial Inst Publ Hlth, Panama City, Panama Dept Publ Hlth, Nay Pyi Taw, Myanmar Univ Brescia, Brescia, Italy Helmholtz Zentrum Munchen, Neuherberg, Germany Univ Eastern Finland, Kuopio, Finland Mary Immaculate Coll, Tours, France Bushehr Univ Med Sci, Bushehr, Iran Ulm Univ, Ulm, Germany Inst Publ Hlth, Kuala Lumpur, Malaysia Kobe Univ, Kobe, Hyogo, Japan Banska Bystrica Reg Author Publ Hlth, Banska Bystrica, Slovakia Suraj Eye Inst, Nagpur, Maharashtra, India Helen Keller Int, Yaounde, Cameroon Karolinska Inst, Solna, Sweden Natl Inst Hyg & Epidemiol, Hanoi, Vietnam Univ Pharm & Med Ho Chi Minh City, Ho Chi Minh City, Vietnam Hanoi Med Univ, Hanoi, Vietnam Miami Vet Affairs Healthcare Syst, Miami, FL USA Heartfile, Islamabad, Pakistan Natl Canc Ctr, Tokyo, Japan Eastern Mediterranean Publ Hlth Network, Amman, Jordan State Univ Med & Pharm, Kishinev, Moldova Tachikawa Gen Hosp, Tachikawa, Tokyo, Japan Acad Hosp Paramaribo, Paramaribo, Surinam Univ Vale Rio dos Sinos, Sao Leopoldo, Brazil Natl Food & Nutr Inst, Warsaw, Poland Minist Hlth, Bandar Seri Begawan, Brunei Univ Fed Santa Catarin, Florianopolis, SC, Brazil Univ Madeira, Funchal, Portugal Univ Puerto Rico, San Juan, PR USA MRC Lifecourse Epidemiol Unit, Southampton, Hants, England Aarhus Univ, Aarhus, Denmark Kwame Nkrumah Univ Sci & Technol, Kumasi, Ghana Inst Social & Prevent, Lausanne, Switzerland Canc Prevent & Res Inst, Florence, Italy Univ Wisconsin Madison, Madison, WI USA IRCCS Casa Sollievo Sofferenz, San Giovanni Rotondo, Italy Zayed Univ, Dubai, U Arab Emirates Catholic Univ Daegu, Gyongsan, South Korea Tg Mures Univ Med & Pharm, Targu Mures, Romania Jivandeep Hosp, Surat, India South African Med Res Council, Tygerberg, South Africa Univ Med Ctr Utrecht, Utrecht, Netherlands Fundacao Oswaldo Cruz, Rene Rachou Res Inst, Rio De Janeiro, Brazil Spanish Agcy Consumer Affairs Social Serv & Nutr, Madrid, Spain Univ Puerto Rico, Med Sci Campus, San Juan, PR USA Minist Hlth & Med Educ, Tehran, Iran Vietnam Natl Heart Inst, Hanoi, Vietnam Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany Univ Sarajevo, Sarajevo, Bosnia & Herceg Cardiovasc Prevent Ctr Udine, Udine, Italy Univ Hosp Pisa, Pisa, Italy Minist Hlth & Med Serv, Honiara, Solomon Islands Publ Hlth Agcy Catalonia, Barcelona, Spain Univ Kebangsaan Malaysia, Kuala Lumpur, Malaysia Univ Montenegro, Podgorica, Montenegro Inst Hosp Mar Invest Med, Barcelona, Spain Agcy Prevent and Social Med, Innsbruck, Austria Digest Oncol Res Ctr, Tehran, Iran Digest Dis Res Inst, Tehran, Iran CHU Vaudois, Lausanne, Switzerland Ctr Dis & Prevent Control, Riga, Latvia Al Quds Univ, Jerusalem, Israel Alborz Univ Med Sci, Karaj, Iran Minist Hlth, Hanoi, Vietnam BRAC, Dhaka, Bangladesh Inst Epidemiol Dis Control & Res, Dhaka, Bangladesh Univ Turku, Turku, Finland India Diabet Res Fdn, Madras, Tamil Nadu, India Univ New South Wales, Sydney, NSW, Australia Inst Univ Invest Atencio Primaria Jordi Gol, Barcelona, Spain Univ Malaya, Kuala Lumpur, Malaysia Univ Valencia, Valencia, Spain Univ Philippines, Quezon City, Philippines Nutr Res Fdn, Barcelona, Spain Minas Gerais State Secretariat Hlth, Belo Horizonte, MG, Brazil Hlth Ctr San Agustin, San AgustIn, Spain PharmAccess Fdn, Amsterdam, Netherlands Natl Inst Hlth Doutor Ricardo Jorge, Lisbon, Portugal Publ Hlth Agcy Canada, Ottawa, ON, Canada Canarian Hlth Serv, Barcelona, Spain Univ Ind Santander, Bucaramanga, Colombia Inst Nacl Salud Publ, Mexico City, DF, Mexico CIBEROBN, Madrid, Spain Gothenburg Univ, Gothenburg, Sweden Fiji Natl Univ, Suva, Fiji CNR, Inst Food Sci, Rome, Italy Sitaram Bhartia Inst Sci & Res, New Delhi, India Univ Tunis El Mana, Tunis, Tunisia Natl Inst Publ Hlth, Mexico City, DF, Mexico Univ Helsinki, Helsinki, Finland Natl Inst Hlth Peru, Lima, Peru Minist Hlth, South Jakarta, Indonesia Catalan Dept Hlth, Barcelona, Spain Publ Hlth Subdelegate Off, Barcelona, Spain Univ Lisbon, Lisbon, Portugal Prevent Med & Publ Hlth, Lisbon, Portugal Univ Sao Paulo, Clin Hosp, Sao Paulo, Brazil South Karelia Social & Hlth Care Dist, Lappeenranta, Finland Isfahan Cardiovasc Res Ctr, Esfahan, Iran Hosp Italiano Buenos Aires, Buenos Aires, DF, Argentina Rigshosp, Copenhagen, Denmark Minist Hlth, Naypyidaw, Myanmar Lagos State Univ, Coll Med, Lagos, Nigeria Univ Las Palmas Gran Canaria, Las Palmas Gran Canaria, Spain Baker Heart and Diabet Inst, Melbourne, Vic, Australia Univ Tokyo, Tokyo, Japan Samsung Med Ctr, Seoul, South Korea Finnish Inst Occupat Hlth, Helsinki, Finland St Vincents Hosp, Melbourne, Vic, Australia Acad Med Ctr Amsterdam, Amsterdam, Netherlands Hlth Polytech Jakarta II Inst, Jakarta, Indonesia Univ Bari, Bari, Italy Inst Reg Sante Publ, Cotonou, Benin Univ Bordeaux, Bordeaux, France Inst Publ Hlth Republ Macedonia, Skopje, Macedonia Univ Leuven, Leuven, Belgium Lamprecht & Stamm Sozialforsch & Beratung AG, Zurich, Switzerland INSERM, Paris, France Univ Bonn, Bonn, Germany Sotiria Hosp, Athens, Greece Natl Inst Publ Hlth, Natl Inst Hyg, Warsaw, Poland Swansea Univ, Swansea, W Glam, Wales Fu Jen Catholic Univ, New Taipei, Taiwan Minist Hlth, Amman, Jordan Natl Inst Hlth, Lima, Peru UNICEF, Yaounde, Cameroon Danish Canc Soc Res Ctr, Copenhagen, Denmark Hlth Serv Murcia, Murcia, Spain Res & Educ Inst, Nicosia, Cyprus IB SALUT Area Salut Menorca, Palma de Mallorca, Spain Univ Bologna, Bologna, Italy Hellen Hlth Fdn, Athens, Greece Univ Pharm & Med Ho Chi Min City, Ho Chi Minh, Vietnam Governm Med Coll, Secunderabad, India Sefako Makgatho Hlth Sci Univ, Kangnung, South Korea Addis Ababa Univ, Addis Ababa, Ethiopia Dasman Diabet Inst, Kuwait, Kuwait Minist Hlth, Thorndon, New Zealand Hellen Med Associat Obes, Athens, Greece Univ Ctr Occidental Lisandro Alvarado, Barquisimeto, Venezuela Meharry Med Coll, Nashville, TN USA Dokuz Eylul Univ, Izmir, Turkey Univ Tampere, Tays Eye Ctr, Tampere, Finland Polytech Inst Porto, Oporto, Portugal Univ Utrecht, Utrecht, Netherlands Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands Fed Univ Pelota, Pelotas, Brazil Italian Natl Res Council, Rome, Italy Univ Miguel Hernandez, Elche, Spain Minist Hlth, Victoria, Seychelles North Karelian Ctr Publ Hlth, Joensuu, Finland ISGlobal Ctr Res Environm Epidemiol, Barcelona, Spain Univ Witwatersrand, Johannesburg, South Africa Med Univ Vienna, Vienna, Austria Univ Coll Cork, Cork, Ireland Inst Med Res, Kuala Lumpur, Malaysia Xinjiang Med Univ, Urumqi, Peoples R China St Georges Univ London, London, England Univ Indonesia, Depok, Indonesia Natl Inst Hyg, Warsaw, Poland Caja Costarricense Seguro Social, Atenas, Costa Rica Univ Kebangsaan Malaysia, Bangi Selangor, Malaysia Univ New South Wales, Kensington, NSW, Australia Univ Mancheste, Manchester, Lancs, England Shandong Univ Tradit Chinese Med, Jinan, Shandong, Peoples R China Kailuan Gen Hosp, Tangshan, Peoples R China Minist Agr, Inst Food & Dev, Beijing, Peoples R China Fudan Univ, Childrens Hosp, Shanghai, Peoples R China Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China Univ Cyprus, Nicosia, Cyprus Univ Teknol MARA, Shah Alam, Malaysia Capital Med Univ Beijing, An Zhen Hosp, Beijing, Peoples R China West Kazakhstan State Med Univ, Aktobe, Kazakhstan Inner Mongolia Med Univ, Hohhot, Peoples R China Gorgas Mem Inst Publ Hlth, Panama City, Panama Univ Estadual Paulista, Sao Paulo, Brazil
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34. Does exposure to phthalates influence thyroid function and growth hormone homeostasis?:the Taiwan environmental survey for toxicants (TEST) 2013
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Huang, H.-B. (Han-Bin), Pan, W.-H. (Wen-Harn), Chang, J.-W. (Jung-Wei), Chiang, H.-C. (Hung-Che), Guo, Y. L. (Yue Leon), Jaakkola, J. J. (Jouni J.K.), and Huang, P.-C. (Po-Chin)
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thyroid hormones ,Phthalate metabolites ,Taiwanese ,growth hormone biomonitoring - Abstract
Background: Previous epidemiologic and toxicological studies provide some inconsistent evidence that exposure to phthalates may affect thyroid function and growth hormone homeostasis. Objective: To assess the relations between exposure to phthalates and indicators of thyroid function and growth hormone homeostasis disturbances both among adults and minors. Methods: We conducted a population-based cross-sectional study of 279 Taiwanese adults (≥18 years old) and 79 minors (
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- 2017
35. P5371Gender differences in sympathetic nervous system activity and 24-hour ambulatory blood pressure in young-onset hypertension patients
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Huang, C.-C, primary, Chung, C.-M, additional, Leu, H.-B, additional, Lin, L.-Y, additional, Huang, P.-H, additional, Lin, S.-J, additional, Pan, W.-H, additional, and Chen, J.-W, additional
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- 2018
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36. P371 Vedolizumab is associated with changes in innate rather than T-cell immunity in patients with inflammatory bowel disease
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Zeissig, S, primary, Rosati, E, additional, Dowds, C M, additional, Aden, K, additional, Bethge, J, additional, Schulte, B, additional, Pan, W H, additional, Falk-Paulsen, M, additional, Conrad, C, additional, Schuldt, D, additional, Sinha, A, additional, Nikolaus, S, additional, Arlt, A, additional, Kabelitz, D, additional, Ellrichmann, M, additional, Rosenstiel, P, additional, Franke, A, additional, and Schreiber, S, additional
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- 2018
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37. Correction to: Impact of nonoptimal intakes of saturated, polyunsaturated, and trans fat on global burdens of coronary heart disease. [J Am Heart Assoc. (2016) 5, e002891.] Doi:10.1161/JAHA.115.002891
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Wang, Q. Afshin, A. Yakoob, M.Y. Singh, G.M. Rehm, C.D. Khatibzadeh, S. Micha, R. Shi, P. Mozaffarian, D. Ezzati, M. Fahimi, S. Wirojratana, P. Powles, J. Elmadfa, I. Rao, M. Alpert, W. Lim, S.S. Engell, R.E. Andrews, K.G. Abbott, P.A. Abdollahi, M. Abeyá Gilardon, E.O. Ahsan, H. Al Nsour, M.A.A. Al-Hooti, S.N. Arambepola, C. Fernando, D.N. Barennes, H. Barquera, S. Baylin, A. Becker, W. Bjerregaard, P. Bourne, L.T. Capanzana, M.V. Castetbon, K. Chang, H.-Y. Chen, Y. Cowan, M.J. Riley, L.M. De Henauw, S. Ding, E.L. Duante, C.A. Duran, P. Barbieri, H.E. Farzadfar, F. Hadziomeragic, A.F. Fisberg, R.M. Forsyth, S. Garriguet, D. Gaspoz, J.-M. Gauci, D. Calleja, N. Ginnela, B.N.V. Guessous, I. Gulliford, M.C. Hadden, W. Haerpfer, C. Hoffman, D.J. Houshiar-Rad, A. Huybrechts, I. Hwalla, N.C. Ibrahim, H.M. Inoue, M. Jackson, M.D. Johansson, L. Keinan-Boker, L. Kim, C.-I. Koksal, E. Lee, H.-J. Li, Y. Lipoeto, N.I. Ma, G. Mangialavori, G.L. Matsumura, Y. McGarvey, S.T. Fen, C.M. Monge-Rojas, R.A. Musaiger, A.O. Nagalla, B. Naska, A. Ocke, M.C. Oltarzewski, M. Szponar, L. Orfanos, P. Ovaskainen, M.-L. Tapanainen, H. Pan, W.-H. Panagiotakos, D.B. Pekcan, G.A. Petrova, S. Piaseu, N. Pitsavos, C. Posada, L.G. Sánchez-Romero, L.M. Selamat, R.B.T. Sharma, S. Sibai, A.M. Sichieri, R. Simmala, C. Steingrimsdottir, L. Swan, G. Sygnowska, E.H. Templeton, R. Thanopoulou, A. Thorgeirsdóttir, H. Thorsdottir, I. Trichopoulou, A. Tsugane, S. Turrini, A. Vaask, S. van Oosterhout, C. Veerman, J.L. Verena, N. Waskiewicz, A. Zaghloul, S. Zajkás, G.
- Abstract
In the article by Wang et al, "Impact of Nonoptimal Intakes of Saturated, Polyunsaturated, and Trans Fat on Global Burdens of Coronary Heart Disease," which published online January 20, 2016, and appeared in the January 2016 issue of the journal (J Am Heart Assoc. 2016;5:e002891 doi:10.1161/ JAHA.115.002891), the full list of the Global Burden of Diseases Nutrition and Chronic Diseases Expert Group (NutriCoDE) group were erroneously listed as authors in the HTML version of the article. The publisher regrets the error. The online version of the article has been updated and is available at http://jaha.ahajournals.org/content/5/1/ e002891. © 2016 The Authors.
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- 2016
38. Impact of nonoptimal intakes of saturated, polyunsaturated, and trans fat on global burdens of coronary heart disease
- Author
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Wang, Q. Afshin, A. Yakoob, M.Y. Singh, G.M. Rehm, C.D. Khatibzadeh, S. Micha, R. Shi, P. Mozaffarian, D. Ezzati, M. Fahimi, S. Wirojratana, P. Powles, J. Elmadfa, I. Rao, M. Alpert, W. Lim, S.S. Engell, R.E. Andrews, K.G. Abbott, P.A. Abdollahi, M. Abeyá Gilardon, E.O. Ahsan, H. Al Nsour, M.A.A. Al-Hooti, S.N. Arambepola, C. Fernando, D.N. Barennes, H. Barquera, S. Baylin, A. Becker, W. Bjerregaard, P. Bourne, L.T. Capanzana, M.V. Castetbon, K. Chang, H.-Y. Chen, Y. Cowan, M.J. Riley, L.M. De Henauw, S. Ding, E.L. Duante, C.A. Duran, P. Barbieri, H.E. Farzadfar, F. Hadziomeragic, A.F. Fisberg, R.M. Forsyth, S. Garriguet, D. Gaspoz, J.-M. Gauci, D. Calleja, N. Ginnela, B.N.V. Guessous, I. Gulliford, M.C. Hadden, W. Haerpfer, C. Hoffman, D.J. Houshiar-Rad, A. Huybrechts, I. Hwalla, N.C. Ibrahim, H.M. Inoue, M. Jackson, M.D. Johansson, L. Keinan-Boker, L. Kim, C.-I. Koksal, E. Lee, H.-J. Li, Y. Lipoeto, N.I. Ma, G. Mangialavori, G.L. Matsumura, Y. McGarvey, S.T. Fen, C.M. Monge-Rojas, R.A. Musaiger, A.O. Nagalla, B. Naska, A. Ocke, M.C. Oltarzewski, M. Szponar, L. Orfanos, P. Ovaskainen, M.-L. Tapanainen, H. Pan, W.-H. Panagiotakos, D.B. Pekcan, G.A. Petrova, S. Piaseu, N. Pitsavos, C. Posada, L.G. Sánchez-Romero, L.M. Selamat, R.B.T. Sharma, S. Sibai, A.M. Sichieri, R. Simmala, C. Steingrimsdottir, L. Swan, G. Sygnowska, E.H. Templeton, R. Thanopoulou, A. Thorgeirsdóttir, H. Thorsdottir, I. Trichopoulou, A. Tsugane, S. Turrini, A. Vaask, S. van Oosterhout, C. Veerman, J.L. Verena, N. Waskiewicz, A. Zaghloul, S. Zajkás, G.
- Abstract
Background: Saturated fat (SFA), x-6 (n-6) polyunsaturated fat (PUFA), and trans fat (TFA) influence risk of coronary heart disease (CHD), but attributable CHD mortalities by country, age, sex, and time are unclear. Methods and Results: National intakes of SFA, n-6 PUFA, and TFA were estimated using a Bayesian hierarchical model based on country-specific dietary surveys; food availability data; and, for TFA, industry reports on fats/oils and packaged foods. Etiologic effects of dietary fats on CHD mortality were derived from meta-analyses of prospective cohorts and CHD mortality rates from the 2010 Global Burden of Diseases study. Absolute and proportional attributable CHD mortality were computed using a comparative risk assessment framework. In 2010, nonoptimal intakes of n-6 PUFA, SFA, and TFA were estimated to result in 711 800 (95% uncertainty interval [UI] 680 700-745 000), 250 900 (95% UI 236 900-265 800), and 537 200 (95% UI 517 600-557 000) CHD deaths per year worldwide, accounting for 10.3% (95% UI 9.9%-10.6%), 3.6%, (95% UI 3.5%-3.6%) and 7.7% (95% UI 7.6%-7.9%) of global CHD mortality. Tropical oil-consuming countries were estimated to have the highest proportional n-6 PUFA- and SFAattributable CHD mortality, whereas Egypt, Pakistan, and Canada were estimated to have the highest proportional TFA-attributable CHD mortality. From 1990 to 2010 globally, the estimated proportional CHD mortality decreased by 9% for insufficient n-6 PUFA and by 21% for higher SFA, whereas it increased by 4% for higher TFA, with the latter driven by increases in low- and middle-income countries. Conclusions: Nonoptimal intakes of n-6 PUFA, TFA, and SFA each contribute to significant estimated CHD mortality, with important heterogeneity across countries that informs nation-specific clinical, public health, and policy priorities. © 2016 The Authors.
- Published
- 2016
39. Changes in the FEV1/FVC ratio during childhood and adolescence: an intercontinental study
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Quanjer, P. H., Stanojevic, S., Stocks, J., Hall, G. L., Prasad, K. V. V., Cole, T. J., Rosenthal, M., Perez-Padilla, R., Hankinson, J. L., Falaschetti, E., Golshan, M., Brunekreef, B., Al-Rawas, O., Kuhr, J., Trabelsi, Y., M. S. M., Ip, Al-Rawas, O. A., Badier, M., Baur, X., Beardsmore, C., Culver, B., Custovic, A., Dejsomritrutai, W., Eigen, H., Enright, P. L., Fallon, B., Fulambarker, A., Gerbase-Weidenbach, M., Gappa, M., Gore, C., Henderson, J., Jones, M., Kerby, G., Kirkby, J., Ku hr, J., Kuster, S., Langhammer, A., Lum, S., Nystad, W., Y. M., Oh, Pan, W-H., Piccioni, P., Pistelli, F., Soriano, J., Thomas, F., Tomalak, W., Turner, S., Vilozni, D., Vlachos-Mayer, H., West, S., Zagami, D., Zheng, J. P., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS, and Pediatrics
- Subjects
Pulmonary and Respiratory Medicine ,Thorax ,Male ,medicine.medical_specialty ,Pediatrics ,Vital capacity ,Adolescent ,Vital Capacity ,Pulmonary function testing ,FEV1/FVC ratio ,Young Adult ,Child Development ,Internal medicine ,Forced Expiratory Volume ,medicine ,Respiratory muscle ,Ethnicity ,Humans ,Lung volumes ,Growth and development ,Lung volume measurements ,Sitting height ,Child ,Child, Preschool ,Female ,Lung ,Adolescent Development ,Preschool ,Body proportions ,business.industry ,respiratory system ,respiratory tract diseases ,El Niño ,Cardiology ,business ,circulatory and respiratory physiology - Abstract
In children, the ratio of forced expiratory volume in 1 s (FEV 1 ) to forced vital capacity (FVC) is reportedly constant or falls linearly with age, whereas the ratio of residual volume (RV) to total lung capacity (TLC) remains constant. This seems counter-intuitive given the changes in airway properties, body proportions, thoracic shape and respiratory muscle function that occur during growth. The age dependence of lung volumes, FEV 1 /FVC and RV/TLC were studied in children worldwide. Spirometric data were available for 22,412 healthy youths (51.4% male) aged 4–20 yrs from 15 centres, and RV and TLC data for 2,253 youths (56.7% male) from four centres; three sets included sitting height (SH). Data were fitted as a function of age, height and SH. In childhood, FVC outgrows TLC and FEV 1 , leading to falls in FEV 1 /FVC and RV/TLC; these trends are reversed in adolescence. Taking into account SH materially reduces differences in pulmonary function within and between ethnic groups. The highest FEV 1 /FVC ratios occur in those shortest for their age. When interpreting lung function test results, the changing pattern in FEV 1 /FVC and RV/TLC should be considered. Prediction equations for children and adolescents should take into account sex, height, age, ethnic group, and, ideally, also SH.
- Published
- 2010
40. Markers of lipoprotein lipase and angiotensin I converting enzyme are linked to young-onset hypertension in Taiwan
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Fann, C.S., Chen, J.-W., Jou, Y.-S., Wu, S.-Y., and Pan, W.-H.
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Human genetics -- Research ,Hypertension -- Genetic aspects ,Biological sciences - Published
- 2000
41. Metabolic mediators of the effects of body-mass index, overweight, and obesity on coronary heart disease and stroke: A pooled analysis of 97 prospective cohorts with 1·8 million participants
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Lu, Y. Hajifathalian, K. Ezzati, M. Woodward, M. Rimm, E.B. Danaei, G. Selmer, R. Strand, B.H. Dobson, A. Hozawa, A. Nozaki, A. Okayama, A. Rodgers, A. Tamakoshi, A. Zhou, B.F. Zhou, B. Yao, C.H. Jiang, C.Q. Gu, D.F. Heng, D. Giles, G.G. Shan, G.L. Whitlock, G. Arima, H. Kim, H.C. Christensen, H. Horibe, H. Maegawa, H. Tanaka, H. Ueshima, H. Zhang, H.Y. Kim, I.S. Suh, I. Fuh, J.L. Lee, J. Woo, J. Xie, J.X. Zhou, J. Hughes, K. Jamrozik, K. Nakachi, K. Sakata, K. Shimamoto, K. Chen, L.Q. Liu, L.S. Hobbs, M. Iida, M. Kagaya, M. Divitini, M.L. Luszcz, M. Nakamura, M. Huang, M.S. Knuiman, M.W. Aoki, N. Norman, P. Sritara, P. Yang, Q.D. Broadhurst, R. Huxley, R. Jackson, R. Norton, R. Ameratunga, S. Ho, S.C. Li, S.C. Jee, S.H. Chew, S.K. Macmahon, S. Choudhury, S.R. Saitoh, S. Yao, S.X. Welborn, T.A. Lam, T.H. Hashimoto, T. Ohkubo, T. Pan, W.-H. Duan, X.F. Fang, X. Wu, X.G. Fang, X.H. Yu, X.H. Li, Y.H. He, Y. Imai, Y. Kita, Y. Kiyohara, Y. Matsutani, Y. Hong, Z. Wu, Z.L. Chen, Z.M. Wu, Z.S. Tang, Z. Li, Z.Z. Parker, E.D. Pereira, M.A. Stevens, J. Panagiotakos, D.B. Pitsavos, C. Attia, J.R. D’este, C.A. Zhang, X. Clays, E. De Bacquer, D.A.O. Van Herck, K. Morrison, H.I. Wang, F. Chuang, S.-Y. Yeh, W.-T. Chen, Z. Smith, M.C. Zhou, M. Wang, W. Zhang, X.-T. Zhao, D. Vollset, S.E. Fuchs, S.C. Fuchs, F.D. Moreira, L.B. Dontas, I.A. Dontas, C.A. Kafatos, A.G. Moschandreas, J. Lanti, M. Menotti, A. Kromhout, D. Jensen, M.K. Overvad, K. Tjonneland, A. Klotsche, J. Wittchen, H.-U. Fischer, S. Hanefeld, M. Schwanebeck, U. Simons, L.A. Simons, J. Bender, R. Matthies, S. Nissinen, A. Tolonen, H.K. Tuomilehto, J. Chaturvedi, N. Fuller, J.H. Soedamah-Muthu, S.S. Kotseva, K. Wood, D.A. Bots, M.L. Moons, K.G.M. Heliovaara, M. Knekt, P.B. Rissanen, H. Ferrie, J.E. Shipley, M.J. Smith, G.D. Johansson, S. Lappas, G. Rosengren, A. Sham, A. Yu, R.H.Y. Hata, J. Ninomiya, T. Hoshide, S. Kario, K. Rastenyte, D. Tamosiunas, A. de Simone, G. Devereux, R.B. Gerdts, E. Colquhoun, D.M. Keech, A.C. Kirby, A.C. Mizuno, K. Nakamura, H. Uchiyama, S. Bassett, J.K. Hodge, A.M. Wilhelmsen, L. Dhaliwal, S.S. Nakamura, Y. Kadota, A. Okamura, T. Sandvei, M.S. Vatten, L.J. Vik, A. Morkedal, B. Romundstad, P.R. Elkind, M.S.V. Gardener, H. Sacco, R.L. Mignano, A. Novo, S. Rizzo, M. Assmann, G. Schulte, H. Lissner, L. Skoog, I. Sundh, V. Marin, A. Medrano, M.J. Hofman, A. Kuningas, M. Stricker, B.H. van der Graaf, Y. Visseren, F.L.J. Lee, J.J.M. Bemelmans, W. de Groot, L.C.P.G.M. de Hollander, E.L. Adachi, H. Hirai, Y. Azizi, F. Hadaegh, F. Khalili, D. Mathiesen, E.B. Njolstad, I. Wilsgaard, T. Can, G. Onat, A. Arnlov, J. Sundstrom, J. Blackburn, H.W. Jacobs, D.R. Averna, M.R. Cefalu, A.B. Noto, D. Concin, H. Nagel, G. Ulmer, H. Krasnow, R.E. Swan, G.E. Kivimaki, M. David Batty, G. Milic, N. Ostojic, M.C. Parapid, B. Geleijnse, J.M. Waterham, E. Feskens, E.J. The Global Burden of Metabolic Risk Factors for Chronic Diseases Collaboration (BMI Mediated Effects)
- Abstract
Background Body-mass index (BMI) and diabetes have increased worldwide, whereas global average blood pressure and cholesterol have decreased or remained unchanged in the past three decades. We quantified how much of the effects of BMI on coronary heart disease and stroke are mediated through blood pressure, cholesterol, and glucose, and how much is independent of these factors. Methods We pooled data from 97 prospective cohort studies that collectively enrolled 1·8 million participants between 1948 and 2005, and that included 57 161 coronary heart disease and 31 093 stroke events. For each cohort we excluded participants who were younger than 18 years, had a BMI of lower than 20 kg/m2, or who had a history of coronary heart disease or stroke. We estimated the hazard ratio (HR) of BMI on coronary heart disease and stroke with and without adjustment for all possible combinations of blood pressure, cholesterol, and glucose. We pooled HRs with a random-effects model and calculated the attenuation of excess risk after adjustment for mediators. Findings The HR for each 5 kg/m2 higher BMI was 1·27 (95% CI 1·23-1·31) for coronary heart disease and 1·18 (1·14-1·22) for stroke after adjustment for confounders. Additional adjustment for the three metabolic risk factors reduced the HRs to 1·15 (1·12-1·18) for coronary heart disease and 1·04 (1·01-1·08) for stroke, suggesting that 46% (95% CI 42-50) of the excess risk of BMI for coronary heart disease and 76% (65-91) for stroke is mediated by these factors. Blood pressure was the most important mediator, accounting for 31% (28-35) of the excess risk for coronary heart disease and 65% (56-75) for stroke. The percentage excess risks mediated by these three mediators did not differ significantly between Asian and western cohorts (North America, western Europe, Australia, and New Zealand). Both overweight (BMI ≥25 to
- Published
- 2014
42. Cryptococcus gattii infections in China: extent of the problem?
- Author
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Chen, M., Pan, W.-h., and Boekhout, T.
- Published
- 2013
43. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations
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Quanjer, P. H., Stanojevic, S., Cole, T. J., Baur, X., Hall, G. L., Culver, B. H., Enright, P. L., Hankinson, J. L., M. S. M., Ip, Zheng, J., Stocks, J., Al-Rawas, O. A., Arets, H. G. M., Barbara, C., Barr, R. G., Bateman, E., Beardsmore, C. S., Ben Saad, H., Brunekreef, B., Burney, P. G. J., Dantes, R. B., Dejsomritrutai, W., Dockery, D., Eigen, H., Falaschetti, E., Fallon, B., Fulambarker, A., Gappa, M., Gerbase and the SAPALDIA cohort study, M. W., Gislason, T., Golshan, M., Gore, C. J., Gulsvik, A., Henderson, A. J., Hnizdo, E., Janson, C., Jenkins, C., Jithoo, A., Karrasch and KORA study, S., Kerby, G. S., Kuhr, J., Kuster and LuftiBus study, S., Langhammer and The HUNT Study, A., Lum, S., Mannino, D. M., Marks, G., Miller, A., Mustafa, G., Nizankowska-Mogilnicka, E., Nystad, W., Oh and Korean NHANES, Y-M., Pan, W-H., Perez-Padilla and PLATINO study, R., Piccioni, P., Pistelli, F., Prasad, K. V. V., Rosenthal, M., Schulz and KORA study, H., Soriano and Framingham study, J. B., Tan, W. C., Tomalak, W., Turner and the SEATON study group, S. W., Vilozni, D., Vlachos, H., West, S., Wouters, E. F. M., Wu, Y., Zagami, D., Zheng, J. P., and Pulmonary Medicine
- Subjects
Pulmonary and Respiratory Medicine ,Spirometry ,Gerontology ,Adult ,Male ,Quality Control ,z-score ,Vital capacity ,Adolescent ,Coefficient of variation ,Vital Capacity ,Ethnic group ,Standard score ,Global Health ,Lower limit of normal ,predicted values ,spirometry ,statistical modelling ,FEV1/FVC ratio ,Reference Values ,Forced Expiratory Volume ,medicine ,Range (statistics) ,Ethnicity ,Pulmonary Medicine ,Humans ,Child ,Lung ,Aged ,Aged, 80 and over ,Models, Statistical ,medicine.diagnostic_test ,business.industry ,Age Factors ,Middle Aged ,Skewness ,Child, Preschool ,Female ,business ,Demography - Abstract
The aim of the Task Force was to derive continuous prediction equations and their lower limits of normal for spirometric indices, which are applicable globally. Over 160,000 data points from 72 centres in 33 countries were shared with the European Respiratory Society Global Lung Function Initiative. Eliminating data that could not be used (mostly missing ethnic group, some outliers) left 97,759 records of healthy nonsmokers (55.3% females) aged 2.5-95 yrs. Lung function data were collated and prediction equations derived using the LMS method, which allows simultaneous modelling of the mean (mu), the coefficient of variation (sigma) and skewness (lambda) of a distribution family. After discarding 23,572 records, mostly because they could not be combined with other ethnic or geographic groups, reference equations were derived for healthy individuals aged 3-95 yrs for Caucasians (n=57,395), African-Americans (n=3,545), and North (n=4,992) and South East Asians (n=8,255). Forced expiratory value in 1 s (FEV(1)) and forced vital capacity (FVC) between ethnic groups differed proportionally from that in Caucasians, such that FEV(1)/FVC remained virtually independent of ethnic group. For individuals not represented by these four groups, or of mixed ethnic origins, a composite equation taken as the average of the above equations is provided to facilitate interpretation until a more appropriate solution is developed. Spirometric prediction equations for the 3-95-age range are now available that include appropriate age-dependent lower limits of normal. They can be applied globally to different ethnic groups. Additional data from the Indian subcontinent and Arabic, Polynesian and Latin American countries, as well as Africa will further improve these equations in the future.
- Published
- 2012
44. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians
- Author
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Chen, P. (Ping), Takeuchi, F. (Fumihiko), Lee, J.-Y. (Jong-Young), Li, H. (Huaixing), Wu, J.-Y. (Jer-Yuarn), Liang, J. (Jun), Long, J. (Jirong), Tabara, Y. (Yasuharu), Goodarzi, M. (Mark), Pereira, M.A. (Mark), Kim, Y.J., Go, M.J. (Min Jin), Stram, D.O. (Daniel), Vithana, E.N. (Eranga), Khor, C.C., Liu, J. (Jianjun), Liao, J. (Jie), Ye, X. (Xingwang), Wang, Y. (Yiqin), Lu, L., Young, T.L. (Terri), Lee, J.J.M. (Jeannette), Thai, A.C. (Ah Chuan), Cheng, C-Y. (Ching-Yu), Dam, R.M. (Rob) van, Friedlander, Y. (Yechiel), Heng, C.K. (Chew-Kiat), Koh, W.-P. (Woon-Puay), Chen, C.-H., Chang, L.-C. (Li-Ching), Pan, W.-H. (Wen-Harn), Qi, B. (Bin), Isono, M. (Masato), Zheng, W. (Wei), Cai, Q. (Qiuyin), Gao, Y. (Ying), Yamamoto, K. (Ken), Ohnaka, K. (Keizo), Takayanagi, R. (Ryoichi), Kita, Y. (Yoshikuni), Ueshima, H. (Hirotsugu), Hsiung, C.A. (Chao Agnes), Cui, J. (Jinrui), Sheu, W.H.-H. (Wayne), Rotter, J.I. (Jerome), Chen, Y.D.I. (Yii-Der Ida), Hsu, C. (Chris), Okada, Y. (Yukinori), Kubo, M. (Michiaki), Takahashi, A. (Atsushi), Tanaka, T. (Toshihiro), Rooij, F.J.A. (Frank) van, Ganesh, S.K. (Santhi), Huang, J. (Jian), Huang, T. (Tao), Yuan, J. (Jianmin), Hwang, J.-Y. (Joo-Yeon), Gross, M.D. (Myron), Assimes, T.L. (Themistocles), Miki, T. (Tetsuro), Shu, X.-O. (Xiao-Ou), Qi, L. (Lu), Chen, Y.T., Lin, X. (Xu), Aung, T. (Tin), Wong, T.Y. (Tien Yin), Teo, Y.Y. (Yik Ying), Kim, B.-J. (Bong-Jo), Kato, N. (Norihiro), Tai, E.-S. (E.-Shyong), Chen, P. (Ping), Takeuchi, F. (Fumihiko), Lee, J.-Y. (Jong-Young), Li, H. (Huaixing), Wu, J.-Y. (Jer-Yuarn), Liang, J. (Jun), Long, J. (Jirong), Tabara, Y. (Yasuharu), Goodarzi, M. (Mark), Pereira, M.A. (Mark), Kim, Y.J., Go, M.J. (Min Jin), Stram, D.O. (Daniel), Vithana, E.N. (Eranga), Khor, C.C., Liu, J. (Jianjun), Liao, J. (Jie), Ye, X. (Xingwang), Wang, Y. (Yiqin), Lu, L., Young, T.L. (Terri), Lee, J.J.M. (Jeannette), Thai, A.C. (Ah Chuan), Cheng, C-Y. (Ching-Yu), Dam, R.M. (Rob) van, Friedlander, Y. (Yechiel), Heng, C.K. (Chew-Kiat), Koh, W.-P. (Woon-Puay), Chen, C.-H., Chang, L.-C. (Li-Ching), Pan, W.-H. (Wen-Harn), Qi, B. (Bin), Isono, M. (Masato), Zheng, W. (Wei), Cai, Q. (Qiuyin), Gao, Y. (Ying), Yamamoto, K. (Ken), Ohnaka, K. (Keizo), Takayanagi, R. (Ryoichi), Kita, Y. (Yoshikuni), Ueshima, H. (Hirotsugu), Hsiung, C.A. (Chao Agnes), Cui, J. (Jinrui), Sheu, W.H.-H. (Wayne), Rotter, J.I. (Jerome), Chen, Y.D.I. (Yii-Der Ida), Hsu, C. (Chris), Okada, Y. (Yukinori), Kubo, M. (Michiaki), Takahashi, A. (Atsushi), Tanaka, T. (Toshihiro), Rooij, F.J.A. (Frank) van, Ganesh, S.K. (Santhi), Huang, J. (Jian), Huang, T. (Tao), Yuan, J. (Jianmin), Hwang, J.-Y. (Joo-Yeon), Gross, M.D. (Myron), Assimes, T.L. (Themistocles), Miki, T. (Tetsuro), Shu, X.-O. (Xiao-Ou), Qi, L. (Lu), Chen, Y.T., Lin, X. (Xu), Aung, T. (Tin), Wong, T.Y. (Tien Yin), Teo, Y.Y. (Yik Ying), Kim, B.-J. (Bong-Jo), Kato, N. (Norihiro), and Tai, E.-S. (E.-Shyong)
- Abstract
Glycated hemoglobin A1c (HbA1c) is used as a measure of glycemic control and also as a diagnostic criterion for diabetes. To discover novel loci harboring common variants associated with HbA1c in East Asians, we conducted a meta-analysis of 13 genome-wide association studies (GWAS; N = 21,026). We replicated our findings in three additional studies comprising 11,576 individuals of East Asian ancestry. Ten variants showed associations that reached genome-wide significance in the discovery data set, of which nine (four novel variants at TMEM79 [ P value = 1.3 × 10 -23], HBS1L/MYB [8.5 × 10-15], MYO9B [9.0 × 10-12], and CYBA [1.1 × 10-8] as well as five variants at loci that had been previously identified [CDKAL1, G6PC2/ ABCB11, GCK, ANK1, and FN3KI]) showed consistent evidence of association in replication data sets. These variants explained 1.76% of the variance in HbA1c. Several of these variants (TMEM79, HBS1L/MYB, CYBA, MYO9B, ANK1, and FN3K) showed no association with either blood glucose or type 2 diabetes. Among individuals with nondiabetic levels of fasting glucose (<7.0 mmol/L) but elevated HbA1c (≥6.5%), 36.1% had HbA1c <6.5% after adjustment for these six variants. Our East Asian GWAS meta-analysis has identified novel variants associated with HbA1c as well as demonstrated that the effects of known variants are largely transferable across ethnic groups. Variants affecting erythrocyte parameters rather than glucose metabolism may be relevant to the use of HbA1c for diagnosing diabetes in these populations.
- Published
- 2014
- Full Text
- View/download PDF
45. Multiple nonglycemic genomic loci are newly associated with blood level of glycated hemoglobin in East Asians.
- Author
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Chen, P, Takeuchi, F, Lee, J-Y, Li, H, Wu, J-Y, Liang, J, Long, J, Tabara, Y, Goodarzi, MO, Pereira, MA, Kim, YJ, Go, MJ, Stram, DO, Vithana, E, Khor, C-C, Liu, J, Liao, J, Ye, X, Wang, Y, Lu, L, Young, TL, Lee, J, Thai, AC, Cheng, C-Y, van Dam, RM, Friedlander, Y, Heng, C-K, Koh, W-P, Chen, C-H, Chang, L-C, Pan, W-H, Qi, Q, Isono, M, Zheng, W, Cai, Q, Gao, Y, Yamamoto, K, Ohnaka, K, Takayanagi, R, Kita, Y, Ueshima, H, Hsiung, CA, Cui, J, Sheu, WH-H, Rotter, JI, Chen, Y-DI, Hsu, C, Okada, Y, Kubo, M, Takahashi, A, Tanaka, T, van Rooij, FJA, Ganesh, SK, Huang, J, Huang, T, Yuan, J, Hwang, J-Y, CHARGE Hematology Working Group, Gross, MD, Assimes, TL, Miki, T, Shu, X-O, Qi, L, Chen, Y-T, Lin, X, Aung, T, Wong, T-Y, Teo, Y-Y, Kim, B-J, Kato, N, Tai, E-S, Chen, P, Takeuchi, F, Lee, J-Y, Li, H, Wu, J-Y, Liang, J, Long, J, Tabara, Y, Goodarzi, MO, Pereira, MA, Kim, YJ, Go, MJ, Stram, DO, Vithana, E, Khor, C-C, Liu, J, Liao, J, Ye, X, Wang, Y, Lu, L, Young, TL, Lee, J, Thai, AC, Cheng, C-Y, van Dam, RM, Friedlander, Y, Heng, C-K, Koh, W-P, Chen, C-H, Chang, L-C, Pan, W-H, Qi, Q, Isono, M, Zheng, W, Cai, Q, Gao, Y, Yamamoto, K, Ohnaka, K, Takayanagi, R, Kita, Y, Ueshima, H, Hsiung, CA, Cui, J, Sheu, WH-H, Rotter, JI, Chen, Y-DI, Hsu, C, Okada, Y, Kubo, M, Takahashi, A, Tanaka, T, van Rooij, FJA, Ganesh, SK, Huang, J, Huang, T, Yuan, J, Hwang, J-Y, CHARGE Hematology Working Group, Gross, MD, Assimes, TL, Miki, T, Shu, X-O, Qi, L, Chen, Y-T, Lin, X, Aung, T, Wong, T-Y, Teo, Y-Y, Kim, B-J, Kato, N, and Tai, E-S
- Abstract
Glycated hemoglobin A1c (HbA1c) is used as a measure of glycemic control and also as a diagnostic criterion for diabetes. To discover novel loci harboring common variants associated with HbA1c in East Asians, we conducted a meta-analysis of 13 genome-wide association studies (GWAS; N = 21,026). We replicated our findings in three additional studies comprising 11,576 individuals of East Asian ancestry. Ten variants showed associations that reached genome-wide significance in the discovery data set, of which nine (four novel variants at TMEM79 [P value = 1.3 × 10(-23)], HBS1L/MYB [8.5 × 10(-15)], MYO9B [9.0 × 10(-12)], and CYBA [1.1 × 10(-8)] as well as five variants at loci that had been previously identified [CDKAL1, G6PC2/ABCB11, GCK, ANK1, and FN3KI]) showed consistent evidence of association in replication data sets. These variants explained 1.76% of the variance in HbA1c. Several of these variants (TMEM79, HBS1L/MYB, CYBA, MYO9B, ANK1, and FN3K) showed no association with either blood glucose or type 2 diabetes. Among individuals with nondiabetic levels of fasting glucose (<7.0 mmol/L) but elevated HbA1c (≥6.5%), 36.1% had HbA1c <6.5% after adjustment for these six variants. Our East Asian GWAS meta-analysis has identified novel variants associated with HbA1c as well as demonstrated that the effects of known variants are largely transferable across ethnic groups. Variants affecting erythrocyte parameters rather than glucose metabolism may be relevant to the use of HbA1c for diagnosing diabetes in these populations.
- Published
- 2014
46. Hyperuricemia and incident atrial fibrillation in a normotensive elderly population in Taiwan
- Author
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Chuang, S.-Y., primary, Wu, C.-C., additional, Hsu, P.-F., additional, Chia-Yu Chen, R., additional, Liu, W.-L., additional, Hsu, Y.-Y., additional, and Pan, W.-H., additional
- Published
- 2014
- Full Text
- View/download PDF
47. Skeletal muscle mass and risk of death in an elderly population
- Author
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Chuang, S.-Y., primary, Chang, H.-Y., additional, Lee, M.-S., additional, Chia-Yu Chen, R., additional, and Pan, W.-H., additional
- Published
- 2014
- Full Text
- View/download PDF
48. Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: pooled analysis of prospective data from the Asia Cohort Consortium
- Author
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Chen, Y., primary, Copeland, W. K., additional, Vedanthan, R., additional, Grant, E., additional, Lee, J. E., additional, Gu, D., additional, Gupta, P. C., additional, Ramadas, K., additional, Inoue, M., additional, Tsugane, S., additional, Tamakoshi, A., additional, Gao, Y.-T., additional, Yuan, J.-M., additional, Shu, X.-O., additional, Ozasa, K., additional, Tsuji, I., additional, Kakizaki, M., additional, Tanaka, H., additional, Nishino, Y., additional, Chen, C.-J., additional, Wang, R., additional, Yoo, K.-Y., additional, Ahn, Y.-O., additional, Ahsan, H., additional, Pan, W.-H., additional, Chen, C.-S., additional, Pednekar, M. S., additional, Sauvaget, C., additional, Sasazuki, S., additional, Yang, G., additional, Koh, W.-P., additional, Xiang, Y.-B., additional, Ohishi, W., additional, Watanabe, T., additional, Sugawara, Y., additional, Matsuo, K., additional, You, S.-L., additional, Park, S. K., additional, Kim, D.-H., additional, Parvez, F., additional, Chuang, S.-Y., additional, Ge, W., additional, Rolland, B., additional, McLerran, D., additional, Sinha, R., additional, Thornquist, M., additional, Kang, D., additional, Feng, Z., additional, Boffetta, P., additional, Zheng, W., additional, He, J., additional, and Potter, J. D., additional
- Published
- 2013
- Full Text
- View/download PDF
49. AB1342 Impact of obesity and hyper-triglyceridemia on gout development with or without hyperuricemia –a prospective study in chinese
- Author
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Chen, J.-H., primary, Hsu, C.-C., additional, Chen, P.-Y., additional, and Pan, W.-H., additional
- Published
- 2013
- Full Text
- View/download PDF
50. Cohort profile: the Asia Pacific Cohort Studies Collaboration
- Author
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Woodward, M., Barzi, F., Martiniuk, A., Fang, X., Gu, D. F., Imai, Y., Lam, T. H., Pan, W. H., Rodgers, A., Suh, I., Jee, S. H., Ueshima, H., Huxley, R., Woodward, M., Barzi, F., Martiniuk, A., Fang, X., Gu, D. F., Imai, Y., Lam, T. H., Pan, W. H., Rodgers, A., Suh, I., Jee, S. H., Ueshima, H., and Huxley, R.
- Published
- 2006
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