Search

A Cu–Zr bimetallic catalyst could achieve CO2RR to ethylene in aqueous electrolytes via the interface between Cu and Zr species.

To observe the effect of electroacupuncture (EA) of "Xiusanzhen" ［bilateral "Yingxiang"(LI20)+"Yintang"(GV24Male C57BL/6 mice were randomly divided into control, sham operation, model and EA groups, with 10 mice in each group. The PDD model was established by injecting 6-OHDA into the medial forebrain tract. EA (2 Hz, 1 mA) was applied to unilateral LI20 and GV29 for 20 min once daily for consecutive 14 days. Morris water maze and new object recognition test were used to evaluate the learning and memory ability. Western blot was used to detect the expression of SYN and PSD-95 proteins in hippocampus. Immunofluorescence was used to label Iba-1Compared with the control group, there was no statistical significance in all the observed indexes in the sham operation group. Compared with the sham operation group, the average escape latency (AEL) prolonged significantly ("Xiusanzhen" can alleviate the learning and memory impairment of PDD model mice, and improve the synaptic plasticity of hippocampal CA1 area. The mechanism may be related to the reduction of C1q and C3 deposition in hippocampal CA1 region and the reduction of microglia phagocytosis.

Hydrogenolysis of biomass-derived lignin sources is highly important for the conversion of renewable biomass resources to biofuels. However, lots of developed catalysts suffer from the drawbacks of expensive precious metal catalysts and/or operation under harsh conditions. In the present work, Co–Ni bimetallic catalysts were prepared and applied in catalyzing hydrogenolysis of Caryl–O aromatic ethers with high activities under the promotion of Nb2C MXene additive. Especially, the hydrogenolysis of diphenyl ether (DPE), a 4–O–5 model compound, to cyclohexane (cy) and cyclohexyl alcohol (cy-ol) could be achieved over the Co2Ni1Ox–Nb2C MXene catalytic system at 120 °C and under 5 bar of H2, which are mild conditions in comparison with those for the developed heterogeneous precious-metal-free catalysts. The excellent catalytic performances stemmed from the strong interaction between Co and Ni species and the promotion of Lewis acidic sites offered by Nb2C MXene. The proposed reaction pathway involved the direct hydrogenolysis of DPE route, in which DPE was initially hydrogenolyzed to benzene and phenol. They were further hydrogenated to cy and cy-ol. The present work not only develops a noble-metal-free bimetallic catalyst for utilization of biomass-derived lignin sources, but also provides a novel strategy for using the Nb2C MXene material.

N-heterocycles with quinoline and tetrahydroquinoline structures are highly important in pharmaceutical and chemical industries, and their highly efficient mutual transformations are vital but still challenging. In the present work, AlN supported redox cobalt catalysts (Co3O4/AlN and Co/AlN) were prepared, which could achieve the reversible aerobic oxidative dehydrogenation/hydrogenation of N-heterocycles with good performances. The catalytic performances were stem from the strong interaction between Co species with AlN support, which were confirmed by the characterizations of Raman, XPS, UV–vis DRS, and H2-TPR etc. Both of the catalysts showed good stabilities and reusabilities for the titled reactions. Besides, the gram-scale experiments achieved with good yields to corresponding products, revealing the present protocol possesses great potential applications in industry. The strategy of using redox Co-based catalyst not only provides a potential catalyst for the reversible hydrogenation/oxidative dehydrogenation reactions but also replenishes methods for constructing of other redox catalyst, especially with AlN as a carrier.

Table S1. The phytosterols contents in commonly consumed foods of China. (DOCX 19Â kb)

The study was conducted with 234 7-week-old Gushi female chickens. There were three treatment groups: control, with no added B.subtilis and antibiotic supplementation, and 2 treatment groups receiving feed supplemented with B.subtilis at 2.0×10 10 CFU/kg and flavomycin at 100 g/kg, respectively. Experimental diets were fed in two phases: growth phase (from 7–20 weeks) and production phase (from 21–30 weeks). This study aimed to investigate the supplemental effects of Bacillus subtilis ( B.subtilis ) on growth performance, antioxidant capacity, intestinal immunity of Gushi female chickens. The results displayed that supplementation with B.subtilis showed a higher improvement ( P ) in growth performance compared to birds fed control (0% B.subtilis ) diets during all periods. Compared with the antibiotic group, the average daily weight gain and feed conversion rate of the B.subtilis group were increased by 3.3% and 6.7%, respectively. There was no significant difference between B.subtilis group and antibiotic group ( P>0.05 ) but pronounced trend was noticed (P=0.078). Compared with control and antibiotics groups, total cholesterol (TC), triglycerides (TG) and malondialdehyde (MDA) content in the serum of birds in B.subtilis group were reduced ( P ) and calcium (Ca) was improved ( P ) during growing period. Birds supplemented with B.subtilis showed decrease in caecal Escherichia coli ( E.coli ) count ( P ) and increase in lactobacillus and bifidobacteria counts ( P ). In comparison to control and antibiotic groups, the B.subtilis group had higher ( P ) activities of intestinal digestive enzyme. Collectively, our overall results indicate that B.subtilis had apparent positive effects on growth performance, blood parameters, serum antioxidant enzyme activities and cecal microflora of local chicken breeds.

Magnetic molecularly imprinted polymers (MMIPs) based on poly [2,2’-(p-oxidiphenylene)-5,5’-bibenzimidazole] (OPBI) composites were synthesized for the selective adsorption and detection of nonylphenol (NP) from water samples. During polymerization, Fe3O4@C was used as supporter and magnetic substance and OPBI not only was used as crosslinking agent but also functional monomer. Morphology of Fe3O4@C and MMIPs were investigated by scanning electron microscopy (SEM). The kinetics of adsorption followed the pseudo-first-order model. Selectivity of MMIPs was further demonstrated through HPLC analysis of the water samples, in which bisphenol A (BPA), phenol, 4-nitrophenol (4-NP) and tetrabromobisphenol (TBBPA) were dissolved respectively. The result showed that MMIPs had more effectively recognition capability of NP than other contrasts.

Magnetic chitosan microspheres were prepared with reversed-phase suspension methodology using glutaraldehyde as cross-linking reagent for sorption of PFOS. In this study, the SEM image of MCTS showed that it had well-shaped spherical form with smooth surface, and its mean particle size was 4.2 μm from the particle size analyzer. Additionally, the sorption kinetics followed the mechanism of the pseudo-second-order equation, and the magnetic chitosan microspheres had a high sorption amount of 865.95 mg g-1 for PFOS due to the electrostatic interaction.

Molecular imprinting has been considered as one of the most useful techniques for the preparation of specific receptors. In this study, a novel molecularly imprinted material (MIP) has been developed by combining PFOS as the template with soluble polybenzimidazole which wrapped over the surface of ferroferric oxide as the carrier. Kinetics experimental showed MIP had a sorption amount of 117.6mg/g for PFOS, high than 74.6mg/g of the none-imprinted polymer adsorbents（NIP）. Additionally, in the competitive environment with other pollutants, the sorption amount of PFOS for MIP is greater than NIP, due to the electrostatic interaction in recognizing the target compound.

The exocyst plays a crucial role in the targeting of secretory vesicles to the plasma membrane during exocytosis. It has been shown to be involved in diverse cellular processes including yeast budding. However, the mechanism of the exocyst regulating yeast budding has not been fully elucidated. Here we report a novel interaction between the exocyst component Sec15 and the Ras-family GTPase Rsr1, a master regulator of bud-site-selection system, in the fungus Candida albicans. We present several lines of evidence indicating physical and genetic interaction of Sec15 with Rsr1. In vitro binding assays and co-immunoprecipitation studies showed that Sec15 associated physically with Rsr1. Deletion of RSR1 completely abolished the polarised localisation of Sec15 as well as all the other exocyst components in both yeast and hyphal cells, suggesting a functional interaction between Sec15 and Rsr1. We also show that C. albicans Sec15 interacts directly with the polarity determinant Bem1 and the type V myosin, Myo2. Disruption of the interaction by shutting off SEC15 results in mislocaliztion of Bem1-GFP. These findings highlight the important role of Sec15 in polarised cell growth by providing a direct functional link between bud-site-selection and exocytosis.

To develop a method for simultaneous determination of cis-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (cis-THSG) and trans-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside (trans-THSG) in mice and comparative study of cis-THSG and trans-THSG in pharmacokinetic and tissue distribution.Analyses was performed using a Diamonsil C,18 (250 mm x 4.6 mm, 5 microm) column with acetonitrile-methanol-0.1% acetic acid (11:7: 82) as the mobile phase at a flow rate of 1.0 mL/min. Polydatin was took as the internal standard. The detection wavelength was set at 285 and 320 nm.Intra-day and inter-day RSD were less than 9.47%. The recoveries and stabilities( RE) were ranged from -9.69% to 4.18% and from -9.49% to 1.33%, respectively. The pharmacokinetic parameters showed that the elimination half-life of cis-THSG was longer than that of trans-THSG and the biological availability of cis-THSG was higher than that of trans-THSG. Both cis-THSG and trans-THSG were widely distributed in the tissues. At the same dosage,the tissue concentrations of trans-THSG were greater than those of cis-THSG.The method is specific,sensitive, simple, rapid and suitable for simultaneous determination of cis-THSG and trans-THSG in mice. The results of pharmacokinetic and tissue distribution indicated that there was significant difference between cis-THSG and trans-THSG in vivo.

Starting from the Kubo formula and the the QCD low energy theorem, we study the the bulk viscosity of hot dense quark matter in the PNJL model from the equation of state . We show that the bulk viscosity has a sharp peak near the chiral phase transition, and the ratio of bulk viscosity over entropy rises dramatically in the vicinity of the phase transition. These results agrees with that from lattice and other model calculations. In addition, we show that the increase of chemical potential raises the bulk viscosity., 8 Pages, 3 figures in Latex. arXiv admin note: text overlap with arXiv:1107.5113 by other authors