232 results on '"PAVIE, Juliette"'
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2. Doxycycline prophylaxis and meningococcal group B vaccine to prevent bacterial sexually transmitted infections in France (ANRS 174 DOXYVAC): a multicentre, open-label, randomised trial with a 2 × 2 factorial design
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Aslan, Alexandre, Pintado, Claire, Delaugerre, Constance, Ponscarme, Diane, Dalle, Eve, Chas, Julie, Siguier, Martin, Palich, Romain, Valentin, Marc-Antoine, Yazdanpanah, Yazdan, Lacombe, Karine, Viard, Jean-Paul, Lourenco, Jeremy, Rachline, Anne, Detruchis, Pierre, Diemer, Myriam, Azemar, Laurene, Landowski, Stephanie, Ometsguine, Philippe, Buisson, Martin, Feliho, Philip, Bachelard, Antoine, Phung, Bao, Rioux, Christophe, Proux, Caroline, Le Gac, Sylvie, Schneider, Luminita, Charmak, Aziza, Ktorza, Nadine, Seang, Sophie, Orriere, Thibaut, Sellem, Baptiste, Palacios, Christia, Mebarki, Soraya, Molina, Jean-Michel, Bercot, Beatrice, Assoumou, Lambert, Rubenstein, Emma, Algarte-Genin, Michele, Pialoux, Gilles, Katlama, Christine, Surgers, Laure, Bébéar, Cécile, Dupin, Nicolas, Ouattara, Moussa, Slama, Laurence, Pavie, Juliette, Duvivier, Claudine, Loze, Benedicte, Goldwirt, Lauriane, Gibowski, Severine, Ollivier, Manon, Ghosn, Jade, and Costagliola, Dominique
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- 2024
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3. Daily and on-demand HIV pre-exposure prophylaxis with emtricitabine and tenofovir disoproxil (ANRS PREVENIR): a prospective observational cohort study
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Molina, Jean-Michel, Ghosn, Jade, Assoumou, Lambert, Delaugerre, Constance, Algarte-Genin, Michèle, Pialoux, Gilles, Katlama, Christine, Slama, Laurence, Liegeon, Geoffroy, Beniguel, Lydie, Ohayon, Michel, Mouhim, Hanane, Goldwirt, Lauriane, Spire, Bruno, Loze, Bénédicte, Surgers, Laure, Pavie, Juliette, Lourenco, Jérémy, Ben-Mechlia, Mohamed, Le Mestre, Soizic, Rojas-Castro, Daniela, and Costagliola, Dominique
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- 2022
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4. A 4-days-on and 3-days-off maintenance treatment strategy for adults with HIV-1 (ANRS 170 QUATUOR): a randomised, open-label, multicentre, parallel, non-inferiority trial
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LAMAURY, Isabelle, BANI-SADR, Firouzé, FORCE, Gilles, CHABROL, Amélie, CABY, Fabienne, PATEY, Olivier, FRESARD, Anne, GAGNEUX-BRUNON, Amandine, CHIROUZE, Catherine, DUVIVIER, Claudine, LOURENCO, Jérémie, TOLSMA, Violaine, JANSSEN, Cécile, LEROLLE, Nathalie, CATALAN, Pilartxo, RAMI, Agathe, DE PONTHAUD, Lucile, PICHANCOURT, Gilles, NASRI, Safa, LANDOWSKI, Stéphanie, BOTTERO, Julie, MFUTILA KAYKAY, Flory, PIALOUX, Gilles, BOUCHAUD, Olivier, ABGRALL, Sophie, GATEY, Caroline, WEISS, Laurence, PAVIE, Juliette, SALMON-CERON, Dominique, ZUCMAN, David, LELIEVRE, Jean-Daniel, PALICH, Romain, SIMON, Anne, MEYOHAS, Marie-Caroline, GRAS, Julien, CABIE, André, PIRCHER, Mathilde, MORLAT, Philippe, HESSAMFAR, Mojgam, NEAU, Didier, CAZENAVE, Charles, GENET, Claire, FAUCHER, Jean-François, MAKHLOUFI, Djamila, BOIBIEUX, André, BREGIGEON-RONOT, Sylvie, LAROCHE, Hélène, SAUTEREAU, Aurélie, REYNES, Jacques, MAKINSON, Alain, RAFFI, François, BOLLENGIER-STRAGIER, Olivier, NAQVI, Alissa, CUA, Eric, ROSENTHAL, Eric, ARVIEUX, Cédrick, BUZELE, Rodolphe, REY, David, BATARD, Marie-Laure, BERNARD, Louis, DELOBEL, Pierre, PIFFAUT, Marie, VERDON, Renaud, PIROTH, Lionel, BLOT, Mathieu, LECLERCQ, Pascale, SIGNORI-SCHMUCK, Anne, HULEUX, Thomas, MEYBECK, Agnès, MAY, Thierry, MIAILHES, Patrick, PERPOINT, Thomas, GREDER-BELAN, Alix, ELHARRAR, Brigitte, KHUONG, Marie-Aude, POUPARD, Marie, BLUM, Laurent, MICHAU, Christophe, PRAZUCK, Thierry, PHILIBERT, Patrick, SLAMA, Laurence, HIKOMBO, Hitoto, DARASTEANU, Iuliana, GIRARD, Pierre-Marie, ALVAREZ, Jean-Claude, MATHEZ, Dominique, DE TRUCHIS, Pierre, LANDMAN, Roland, MEYNARD, Jean-Luc, MORAND-JOUBERT, Laurence, LAMBERT, Sidonie, LE DU, Damien, PERRONNE, Christian, ASSOUMOU, Lambert, COSTAGLIOLA, Dominique, MELCHIOR, Jean-Claude, DURACINSKI, Martin, PETROV-SANCHEZ, Ventzislava, AMAT, Karine, BENALYCHERIF, Aïda, SYLLA, Babacar, GELLEY, Ambre, GIBOWSKI, Séverine, LE MEUT, Guillaume, THIEBAUT, Rodolphe, CLUMECK, Nathan, LECLERCQ, Vincent, CECCHERINI-SILBERSTEIN, Francesca, DECOSTER, Laurent, Landman, Roland, de Truchis, Pierre, Assoumou, Lambert, Lambert, Sidonie, Bellet, Jonathan, Amat, Karine, Lefebvre, Bénédicte, Allavena, Clotilde, Katlama, Christine, Yazdanpanah, Yazdan, Molina, Jean-Michel, Petrov-Sanchez, Ventzislava, Gibowski, Séverine, Alvarez, Jean-Claude, Leibowitch, Jacques, Capeau, Jacqueline, Fellahi, Soraya, Duracinsky, Martin, Morand-Joubert, Laurence, Costagliola, Dominique, and Girard, Pierre-Marie
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- 2022
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5. Accuracy of saliva and nasopharyngeal sampling for detection of SARS-CoV-2 in community screening: a multicentric cohort study
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Kernéis, Solen, Elie, Caroline, Fourgeaud, Jacques, Choupeaux, Laure, Delarue, Séverine Mercier, Alby, Marie-Laure, Quentin, Pierre, Pavie, Juliette, Brazille, Patricia, Néré, Marie Laure, Minier, Marine, Gabassi, Audrey, Gibaud, Aurélien, Gauthier, Sébastien, Leroy, Chrystel, Voirin-Mathieu, Etienne, Poyart, Claire, Vidaud, Michel, Parfait, Béatrice, Delaugerre, Constance, Tréluyer, Jean-Marc, and LeGoff, Jérôme
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- 2021
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6. Doxycycline prophylaxis and meningococcal group B vaccine to prevent bacterial sexually transmitted infections in France (ANRS 174 DOXYVAC): a multicentre, open-label, randomised trial with a 2 × 2 factorial design
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Molina, Jean-Michel, primary, Bercot, Beatrice, additional, Assoumou, Lambert, additional, Rubenstein, Emma, additional, Algarte-Genin, Michele, additional, Pialoux, Gilles, additional, Katlama, Christine, additional, Surgers, Laure, additional, Bébéar, Cécile, additional, Dupin, Nicolas, additional, Ouattara, Moussa, additional, Slama, Laurence, additional, Pavie, Juliette, additional, Duvivier, Claudine, additional, Loze, Benedicte, additional, Goldwirt, Lauriane, additional, Gibowski, Severine, additional, Ollivier, Manon, additional, Ghosn, Jade, additional, Costagliola, Dominique, additional, Aslan, Alexandre, additional, Pintado, Claire, additional, Delaugerre, Constance, additional, Ponscarme, Diane, additional, Dalle, Eve, additional, Chas, Julie, additional, Siguier, Martin, additional, Palich, Romain, additional, Valentin, Marc-Antoine, additional, Yazdanpanah, Yazdan, additional, Lacombe, Karine, additional, Viard, Jean-Paul, additional, Lourenco, Jeremy, additional, Rachline, Anne, additional, Detruchis, Pierre, additional, Diemer, Myriam, additional, Azemar, Laurene, additional, Landowski, Stephanie, additional, Ometsguine, Philippe, additional, Buisson, Martin, additional, Feliho, Philip, additional, Bachelard, Antoine, additional, Phung, Bao, additional, Rioux, Christophe, additional, Proux, Caroline, additional, Le Gac, Sylvie, additional, Schneider, Luminita, additional, Charmak, Aziza, additional, Ktorza, Nadine, additional, Seang, Sophie, additional, Orriere, Thibaut, additional, Sellem, Baptiste, additional, Palacios, Christia, additional, and Mebarki, Soraya, additional
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- 2024
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7. Episomal HPV16 responsible for aggressive and deadly metastatic anal squamous cell carcinoma evidenced in peripheral blood
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Péré, Hélène, Vernet, Raphael, Pernot, Simon, Pavie, Juliette, Robillard, Nicolas, Puech, Julien, Lameiras, Sonia, Lucas, Marie-Laure, Nicolas, Alain, Badoual, Cécile, Rance, Bastien, Bélec, Laurent, Weiss, Laurence, Wack, Maxime, and Veyer, David
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- 2021
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8. Missed opportunities for HIV testing in patients newly diagnosed with HIV in Morocco
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Marih, Latifa, Sawras, Victoire, Pavie, Juliette, Sodqi, Mustapha, Malmoussi, Mourad, Tassi, Noura, Bensghir, Rajaa, Nani, Samira, Lahsen, Ahd Oulad, Laureillard, Didier, El Filali, Kamal Marhoum, Champenois, Karen, and Weiss, Laurence
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- 2021
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9. Evaluation of a saliva molecular point of care for the detection of SARS-CoV-2 in ambulatory care
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LeGoff, Jérôme, Kernéis, Solen, Elie, Caroline, Mercier-Delarue, Séverine, Gastli, Nabil, Choupeaux, Laure, Fourgeaud, Jacques, Alby, Marie-Laure, Quentin, Pierre, Pavie, Juliette, Brazille, Patricia, Néré, Marie Laure, Minier, Marine, Gabassi, Audrey, Leroy, Chrystel, Parfait, Béatrice, Tréluyer, Jean-Marc, and Delaugerre, Constance
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- 2021
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10. Human Immunodeficiency Virus Type 1 Group O Infection in France : Clinical Features and Immunovirological Response to Antiretrovirals
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ORIVAO Study, Unal, Guillemette, Alessandri-Gradt, Elodie, Leoz, Marie, Pavie, Juliette, Lefèvre, Clément, Panjo, Henri, Charpentier, Charlotte, Descamps, Diane, Barin, Francis, Simon, François, Meyer, Laurence, and Plantier, Jean-Christophe
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- 2018
11. HIV infection and COVID-19: risk factors for severe disease
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Etienne, Nicolas, Karmochkine, Marina, Slama, Laurence, Pavie, Juliette, Batisse, Dominique, Usubillaga, Rafael, Letembet, Valerie-Anne, Brazille, Patricia, Canouï, Etienne, Slama, Dorsaf, Joumaa, Hassan, Canoui-Poitrine, Florence, Segaux, Lauriane, Weiss, Laurence, Viard, Jean-Paul, and Salmon, Dominique
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- 2020
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12. γδ T-cell subsets in HIV controllers: potential role of Tγδ17 cells in the regulation of chronic immune activation
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Chevalier, Mathieu F., Bhatnagar, Nupur, Didier, Céline, Lopez-Gonzalez, Moises, Pavie, Juliette, Bollens, Diane, Duvivier, Claudine, Collias, Lio, Jung, Corinne, Scott-Algara, Daniel, Girard, Pierre-Marie, and Weiss, Laurence
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- 2019
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13. Comparison of anal cancer screening strategies including standard anoscopy, anal cytology, and HPV genotyping in HIV-positive men who have sex with men
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Pernot, Simon, Boucheron, Pauline, Péré, Hélène, Lucas, Marie-Laure, Veyer, David, Fathallah, Nadia, de Parades, Vincent, Pavie, Juliette, Netter, Jeanne, Collias, Lio, Taieb, Julien, Grabar, Sophie, and Weiss, Laurence
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- 2018
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14. Factors associated with anal cancer screening uptake in men who have sex with men living with HIV: a cross-sectional study
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Vanhaesebrouck, Alexis, Pernot, Simon, Pavie, Juliette, Lucas, Marie-Laure, Collias, Lio, Péré, Hélène, Taieb, Julien, Weiss, Laurence, and Grabar, Sophie
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- 2020
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15. Performance and economic evaluation of the molecular detection of pathogens for patients with severe infections: the EVAMICA open-label, cluster-randomised, interventional crossover trial
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Cambau, Emmanuelle, Durand-Zaleski, Isabelle, Bretagne, Stéphane, Brun-Buisson, Christian, Cordonnier, Catherine, Duval, Xavier, Herwegh, Stéphanie, Pottecher, Julien, Courcol, René, Bastuji-Garin, Sylvie, Lefort, Agnès, Mantz, Jean, Pease, Sébastien, Lavagna, Leïla, Nicolas-Chanoine, Marie Hélène, Leflon, Véronique, Marcon, Estelle, Ruimy, Raymond, Andremont, Antoine, Lebras, Jacques, Iung, Bernard, Regnier, Bernard, Yeni, Patrick, Montravers, Philippe, Mourvillier, Bruno, Ilic-Habensus, Emila, Talbi, Nadia El Alami, Lasocki, Sigismond, Bouscary, Didier, Mira, Jean-Paul, Grimaldi, David, Marin, Nathalie, Doloy, Alexandra, Poyart, Claire, Scherrer, Emmanuel, Chambon-Pautas, Cecile, Cook, Fabrice, Mekontso-Dessap, Armand, Schortgen, Frédérique, Chedevergne, Karine, Vernant, Jean-Paul, Gauvin-Bodin, Liliane, Trouillet, Jean-Louis, Chastre, Jean, Bricaire, François, Brossier, Florence, Jarlier, Vincent, Dheder, Nathalie, Nieszkowska, Ania, Datry, Annick, Fekkar, Arnaud, Buffet, Pierre, Mazier, Rommy, Brun, Sophie, Meyssonnier, Vanina, Isnard, Françoise, Baudel, Jean-Luc, Meynard, Jean-Luc, Petit, Jean-Claude, Lalande, Valérie, Roux, Patricia, Raffoux, Emmanuel, Ribaud, Patricia, Das, Vincent, Schlemmer, Benoit, Azoulay, Elie, Chimot, Loic, Molina, Jean-Michel, Ponscarme, Diane, Pavie, Juliette, Simon, François, Casin, Isabelle, Menotti, Jean, Gruson, Didier, Bessède, Emilie, Guilhon, Emmanuelle, Accoceberry, Isabelle, Millet, Pascal, Bébéar, Cécile, Berthoux, Christian, Tonnelier, Jean-Marie, Garre, Michel, Hery-Arnaud, Geneviève, Payan, Christopher, Nevez, Gilles, Timsit, Jean-Francois, Cahn, Jean-Yves, Brion, Jean-Paul, Le beau, Bernard, Courby, Stephane, Pelloux, Hervé, Maurin, Max, Epaulard, Olivier, Hamidfar, Rebecca, Berthon, Céline, Coiteux, Valérie, Terriou, Louis, Nseir, Saadalla, Auffray, Jean-Luc, Jouet, Jean-Pierre, Durocher, Alain, Faure, Karine, Clavel, Marc, Camus, Daniel, Dugard, Anthony, Tisseuil, Chantal, Duchiron, Cécile, Ajzenberg, Daniel, Bordessoule, Dominique, Garnier, Fabien, François, Bruno, Ploy, Marie-Cécile, Darde, Marie-Laure, Chaury, Marie-Pierre, Giraud, Stephane, Jaccard, Arnaud, Moreau, Stéphane, Réménieras, Liliane, Touati, Mohamed, Turlure, Pascal, Amiel, Jean-Bernard, Pichon, Nicolas, Postil, Déborah, Vignon, Philippe, Espinouse, Daniel, Jacques, Didier, De Monbrison, Frédérique, Grozel, Jean-Michel, Chomarat, Monique, Gueugniaud, Pierre-Yves, Sanogo, Rokiatou, Drancourt, Michel, Fournier, Pierre Edouard, Roux, Véronique, Delmer, Alain, Himberlin, Chantal, Kolb, Brigitte, Lé, Quoc Hung, Appriou, Morgane, Cousson, Joël, Nazeyrollas, Pierre, Strady, Christophe, Dechamps, Christophe, Vernet, Véronique, Delmer, Alain, Toubas, Dominique, Guyotat, Denis, Auboyer, Christian, Zeni, Fabrice, Alamartine, Eric, Cathebras, Pascal, Lucht, Frédéric, Viallon, Alain, Melis, Adrien, Ros, Alain, Carricajo, Anne, Devanlay, Camille, Labruyere, Carine, Vautrin, Catherine, Cazorla, Céline, Tavernier, Emmanuelle, Grattard, Florence, Aubert, Gérald, Morel, Jerome, Cornillon, Jérome, Abba, Karima, Flori, Pierre, Sung, Roger Tran Manh, Pozzetto, Bruno, Schneider, Francis, Hansmann, Yves, Herbrecht, Raoul, Jaulhac, Benoit, Piémont, Yves, Lestcher, Valérie, Colombat, Philippe, Senecal, Delphine, Garot, Denis, Perrottin, Dominique, Besnier, Jean-Marc, Goudeau, Alain, Lanotte, Philippe, Chandenier, Jacques, Baloul, Samia, Corbel, Céline, Dabbech, Moufida, Gaba, Mabel, Jozefowicz, Elsa, Lafaye, Magali, Maugard, Fabien, Rabeuf, Remi, Rabetrano, Hasina, Veerabudun, Kalaivani, Viallette, Cédric, Stahl, Jean-Paul, Delhaes, Laurence, and The EVAMICA study team
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- 2017
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16. Striking differences in weight gain after cART initiation depending on early or advanced presentation: results from the ANRS CO4 FHDH cohort
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Grabar, Sophie, primary, Potard, Valérie, additional, Piroth, Lionel, additional, Abgrall, Sophie, additional, Bernard, Louis, additional, Allavena, Clotilde, additional, Caby, Fabienne, additional, de Truchis, Pierre, additional, Duvivier, Claudine, additional, Enel, Patricia, additional, Katlama, Christine, additional, Khuong, Marie-Aude, additional, Launay, Odile, additional, Matheron, Sophie, additional, Melica, Giovanna, additional, Melliez, Hugues, additional, Meynard, Jean-Luc, additional, Pavie, Juliette, additional, Slama, Laurence, additional, Bregigeon, Sylvie, additional, Tattevin, Pierre, additional, Capeau, Jacqueline, additional, and Costagliola, Dominique, additional
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- 2023
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17. Acquired hemophilia A resolution in a hepatitis C virus/human immunodeficiency virus–coinfected patient with cure of hepatitis C by direct‐acting antiviral agents
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Mauge, Laetitia, Pavie, Juliette, Batisse, Dominique, and Darnige, Luc
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- 2018
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18. Risk of HIV transmission during combined ART initiation for HIV-infected persons with severe immunosuppression
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Supervie, V, Assoumou, L, Breban, R, Lert, F, Costagliola, D, Pialoux, G, Landman, R, Girard, P. M, Slama, L, Cabié, André, Abel, Sylvie, Hochedez, Patrick, Pierre-François, Sandrine, Rozé, Benoît, Simon, Anne, Lupin, Catherine, Katlama, Christine, Valentin, Marc Antoine, Autran, Brigitte, Samri, Assia, Lambert, Sidonie, Marcelin, Anne Geneviève, Landman, Roland, Joly, Véronique, Julia, Zélie, Harent, Stanislas, Papot, Emmanuelle, Phung, Bao-Chau, Peytavin, Gilles, Minh, Patrick Lê, Rami, Agathe, Diemer, Myriam, Parrinello, Maguy, Cahitte, Isabelle, Zeng, Feng, Mortier, Emmanuel, Pialoux, Gilles, L’Yavanc, Thomas, Le Loup, Guillaume, Bonnard, Philippe, Lebrette, Marie Gisèle, Chas, Julie, Berrebi, Valérie, Velazquez, Nadège, Adda, Anne, Duvivier, Claudine, Touam, Fatima, Lortholary, Olivier, Shoai-Tehrani, Michka, Rouzaud, Claire, Denes, Eric, Ducroux-Roubertou, Sophie, Durox, Hélène, Genet, Claire, Rogez, Jean-Philippe, Rogez, Sylvie, Pascual, Jose, Weiss, Laurence, Pavie, Juliette, Bourzam, Erila, Aumaître, Hugues, Ferreyra, Milagros, Saada, Matthieu, Malet, Martine, Palacios, Christia, Honore, Patricia, Zamord, Irene, Berthe, Huguette, Landowski, Stéphanie, de Truchis, Pierre, Perre, Philippe, Girard, Pierre-Marie, Valin, Nadia, Campa, Pauline, Lefebvre, Bénédicte, Meynard, Jean-Luc, Pauchard, Michèle, and Surgers, Laure
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- 2017
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19. Early treatment with sotrovimab monoclonal antibody in kidney transplant recipients with Omicron infection
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Chavarot, Nathalie, Melenotte, Clea, Amrouche, Lucile, Rouzaud, Claire, Sberro-Soussan, Rebecca, Pavie, Juliette, Martinez, Frank, Pouvaret, Anne, Leruez-Ville, Marianne, Cantin, Delphine, Fourgeaud, Jacques, Delage, Claire, Vimpere, Damien, Peraldi, Marie Noëlle, Legendre, Christophe, Lanternier, Fanny, Zuber, Julien, Scemla, Anne, and Anglicheau, Dany
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- 2022
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20. Prevalence of opportunistic intestinal parasitic infections among HIV-infected patients with low CD4 cells counts in France in the combination antiretroviral therapy era
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Pavie, Juliette, Menotti, Jean, Porcher, Raphaël, Donay, Jean Luc, Gallien, Sébastien, Sarfati, Claudine, Derouin, Francis, and Molina, Jean-Michel
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- 2012
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21. A highly virulent variant of HIV-1 circulating in the Netherlands
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Wymant, Chris, Bezemer, Daniela, Blanquart, François, Ferretti, Luca, Gall, Astrid, Hall, Matthew, Golubchik, Tanya, Bakker, Margreet, Ong, Swee Hoe, Zhao, Lele, Bonsall, David, de Cesare, Mariateresa, MacIntyre-Cockett, George, Abeler-Dörner, Lucie, Albert, Jan, Bannert, Norbert, Fellay, Jacques, Grabowski, M Kate, Gunsenheimer-Bartmeyer, Barbara, Günthard, Huldrych F, Kivelä, Pia, Kouyos, Roger D, Laeyendecker, Oliver, Meyer, Laurence, Porter, Kholoud, Ristola, Matti, van Sighem, Ard, Berkhout, Ben, Kellam, Paul, Cornelissen, Marion, Reiss, Peter, Fraser, Christophe, Aubert, V, Battegay, M, Bernasconi, E, Böni, J, Braun, D L, Bucher, H C, Burton-Jeangros, C, Calmy, A, Cavassini, M, Dollenmaier, G, Egger, M, Elzi, L, Fehr, J, Fellay, J, Furrer, H, Fux, C A, Gorgievski, M, Günthard, H, Haerry, D, Hasse, B, Hirsch, H H, Hoffmann, M, Hösli, I, Kahlert, C, Kaiser, L, Keiser, O, Klimkait, T, Kouyos, R, Kovari, H, Ledergerber, B, Martinetti, G, de Tejada, B Martinez, Marzolini, C, Metzner, K, Müller, N, Nadal, D, Nicca, D, Pantaleo, G, Rauch, A, Regenass, S, Rudin, C, Schöni-Affolter, F, Schmid, P, Speck, R, Stöckle, M, Tarr, P, Trkola, A, Vernazza, P, Weber, R, Yerly, S, van der Valk, M, Geerlings, S E, Goorhuis, A, Hovius, J W, Lempkes, B, Nellen, F J B, van der Poll, T, Prins, J M, Reiss, P, van Vugt, M, Wiersinga, W J, Wit, F W M N, van Duinen, M, van Eden, J, Hazenberg, A, van Hes, A M H, Pijnappel, F J J, Smalhout, S Y, Weijsenfeld, A M, Jurriaans, S, Back, N K T, Zaaijer, H L, Berkhout, B, Cornelissen, M T E, Schinkel, C J, Wolthers, K C, Peters, E J G, van Agtmael, M A, Autar, R S, Bomers, M, Sigaloff, K C E, Heitmuller, M, Laan, L M, Ang, C W, van Houdt, R, Jonges, M, Kuijpers, T W, Pajkrt, D, Scherpbier, H J, de Boer, C, van der Plas, A, van den Berge, M, Stegeman, A, Baas, S, Hage de Looff, L, Buiting, A, Reuwer, A, Veenemans, J, Wintermans, B, Pronk, M J H, Ammerlaan, H S M, van den Bersselaar, D N J, de Munnik, E S, Deiman, B, Jansz, A R, Scharnhorst, V, Tjhie, J, Wegdam, M C A, van Eeden, A, Nellen, J, Brokking, W, Elsenburg, L J M, Nobel, H, van Kasteren, M E E, Berrevoets, M A H, Brouwer, A E, Adams, A, van Erve, R, de Kruijf-van de Wiel, B A F M, Keelan-Phaf, S, van der Ven, B, Buiting, A G M, Murck, J L, de Vries-Sluijs, T E M S, Bax, H I, van Gorp, E C M, de Jong-Peltenburg, N C, de Mendonç A Melo, M, van Nood, E, Nouwen, J L, Rijnders, B J A, Rokx, C, Schurink, C A M, Slobbe, L, Verbon, A, Bassant, N, van Beek, J E A, Vriesde, M, van Zonneveld, L M, de Groot, J, Boucher, C A B, Koopmans, M P G, van Kampen, J J A, Fraaij, P L A, van Rossum, A M C, Vermont, C L, van der Knaap, L C, Visser, E, Branger, J, Douma, R A, Cents-Bosma, A S, Duijf-van de Ven, C J H M, Schippers, E F, van Nieuwkoop, C, van Ijperen, J M, Geilings, J, van der Hut, G, van Burgel, N D, Leyten, E M S, Gelinck, L B S, Mollema, F, Davids-Veldhuis, S, Tearno, C, Wildenbeest, G S, Heikens, E, Groeneveld, P H P, Bouwhuis, J W, Lammers, A J J, Kraan, S, van Hulzen, A G W, Kruiper, M S M, van der Bliek, G L, Bor, P C J, Debast, S B, Wagenvoort, G H J, Kroon, F P, de Boer, M G J, Jolink, H, Lambregts, M M C, Roukens, A H E, Scheper, H, Dorama, W, van Holten, N, Claas, E C J, Wessels, E, den Hollander, J G, El Moussaoui, R, Pogany, K, Smit, J V, Struik-Kalkman, D, van Niekerk, T, Pontesilli, O, Lowe, S H, Oude Lashof, A M L, Posthouwer, D, van Wolfswinkel, M E, Ackens, R P, Burgers, K, Schippers, J, Weijenberg-Maes, B, van Loo, I H M, Havenith, T R A, van Vonderen, M G A, Kampschreur, L M, Faber, S, Steeman-Bouma, R, Al Moujahid, A, Kootstra, G J, Delsing, C E, van der Burg-van de Plas, M, Scheiberlich, L, Kortmann, W, van Twillert, G, Renckens, R, Ruiter-Pronk, D, van Truijen-Oud, F A, Cohen Stuart, J W T, Jansen, E R, Hoogewerf, M, Rozemeijer, W, van der Reijden, W A, Sinnige, J C, Brinkman, K, van den Berk, G E L, Blok, W L, Lettinga, K D, de Regt, M, Schouten, W E M, Stalenhoef, J E, Veenstra, J, Vrouenraets, S M E, Blaauw, H, Geerders, G F, 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Godinot, Mathieu, Brunel-Dalmas, Florence, Gibert, Sylvie, Trepo, Christian, Peyramond, Dominique, Miailhes, Patrick, Koffi, Joseph, Thoirain, Valérie, Brochier, Corinne, Baudry, Thomas, Pailhes, Sylvie, Lafeuillade, Alain, Philip, Gisèle, Hittinger, Gilles, Assi, Assi, Lambry, Véronique, Rosenthal, Eric, Naqvi, Alissa, Dunais, Brigitte, Cua, Eric, Pradier, Christian, Durant, Jacques, Joulie, Aline, Quinsat, Denis, Tempesta, Serge, Ravaux, Isabelle, Martin, Isabelle Poizot, Faucher, Olivia, Cloarec, Nicolas, Champagne, Hélène, Pichancourt, Gilles, Morlat, Philippe, Pistone, Thierry, Bonnet, Fabrice, Mercie, Patrick, Faure, Isabelle, Hessamfar, Mojgan, Malvy, Denis, Lacoste, Denis, Pertusa, Marie-Carmen, Vandenhende, Marie-Anne, Bernard, Noëlle, Paccalin, François, Martell, Cédric, Roger-Schmelz, Julien, Receveur, Marie-Catherine, Duffau, Pierre, Dondia, Denis, Ribeiro, Emmanuel, Caltado, Sabrina, Neau, Didier, Dupont, Michel, Dutronc, Hervé, Dauchy, Frédéric, Cazanave, Charles, Vareil, Marc-Olivier, Wirth, Gaétane, Le Puil, Séverine, Pellegrin, Jean-Luc, Raymond, Isabelle, Viallard, Jean-François, Chaigne de Lalande, Severin, Garipuy, Daniel, Delobel, Pierre, Obadia, Martine, Cuzin, Lise, Alvarez, Muriel, Biezunski, Noemie, Porte, Lydie, Massip, Patrice, Debard, Alexa, Balsarin, Florence, Lagarrigue, Myriam, Prevoteau du Clary, François, Aquilina, Christian, Reynes, Jacques, Baillat, Vincent, Merle, Corinne, Lemoing, Vincent, Atoui, Nadine, Makinson, Alain, Jacquet, Jean Marc, Psomas, Christina, Tramoni, Christine, Aumaitre, Hugues, Saada, Mathieu, Medus, Marie, Malet, Martine, Eden, Aurélia, Neuville, Ségolène, Ferreyra, Milagros, Sotto, Albert, Barbuat, Claudine, Rouanet, Isabelle, Leureillard, Didier, Mauboussin, Jean-Marc, Lechiche, Catherine, Donsesco, Régine, Cabie, André, Abel, Sylvie, Pierre-Francois, Sandrine, Batala, Anne-Sophie, Cerland, Christophe, Rangom, Camille, Theresine, Nadine, Hoen, Bruno, Lamaury, Isabelle, Fabre, Isabelle, Schepers, Kinda, Curlier, Elodie, Ouissa, Rachida, Gaud, Catherine, Ricaud, Carole, Rodet, Roland, Wartel, Guillaume, Sautron, Carmele, Beck-Wirth, Geneviève, Michel, Catherine, Beck, Charles, Halna, Jean-Michel, Kowalczyk, Jakub, Benomar, Meryem, Drobacheff-Thiebaut, Christine, Chirouze, Catherine, Faucher, Jean-François, Parcelier, François, Foltzer, Adeline, Haffner-Mauvais, Cécile, Hustache Mathieu, Mathieu, Proust, Aurélie, Piroth, Lionel, Chavanet, Pascal, Duong, Michel, Buisson, Marielle, Waldner, Anne, Mahy, Sophie, Gohier, Sandrine, Croisier, Delphine, May, Thierry, Delestan, Mikael, Andre, Marie, Zadeh, Mahsa Mohseni, Martinot, Martin, Rosolen, Béatrice, Pachart, Anne, Martha, Benoît, Jeunet, Noëlle, Rey, David, Cheneau, Christine, Partisani, Maria, Priester, Michèle, Bernard-Henry, Claudine, Batard, Marie-Laure, Fischer, Patricia, Berger, Jean-Luc, Kmiec, Isabelle, Robineau, Olivier, Huleux, Thomas, Ajana, Faïza, Alcaraz, Isabelle, Allienne, Christophe, Baclet, Véronique, Meybeck, Agnès, Valette, Michel, Viget, Nathalie, Aissi, Emmanuelle, Biekre, Raphael, Cornavin, Pauline, Merrien, Dominique, Seghezzi, Jean-Christophe, Machado, Moise, Diab, Georges, Raffi, François, Bonnet, Bénédicte, Allavena, Clotilde, Grossi, Olivier, Reliquet, Véronique, Billaud, Eric, Brunet, Cecile, Bouchez, Sabelline, Morineau-Le Houssine, Pascale, Sauser, Fabienne, Boutoille, David, Besnier, Michel, Hue, Hervé, Hall, Nolwenn, Brosseau, Delphine, Souala, Faouzi, Michelet, Christian, Tattevin, Pierre, Arvieux, Cédric, Revest, Matthieu, Leroy, Helene, Chapplain, Jean-Marc, Dupont, Matthieu, Fily, Fabien, Patra-Delo, Solène, Lefeuvre, Céline, Bernard, Louis, Bastides, Frédéric, Nau, Pascale, Verdon, Renaud, de la Blanchardiere, Arnaud, Martin, Anne, Feret, Philippe, Geffray, Loïk, Daniel, Corinne, Rohan, Jennifer, Fialaire, Pascale, Chennebault, Jean Marie, Rabier, Valérie, Abgueguen, Pierre, Rehaiem, Sami, Luycx, Odile, Niault, Mathilde, Moreau, Philippe, Poinsignon, Yves, Goussef, Marie, Mouton-Rioux, Virginie, Houlbert, Dominique, Alvarez-Huve, Sandrine, Barbe, Frédérique, Haret, Sophie, Perre, Philippe, Leantez-Nainville, Sophie, Esnault, Jean-Luc, Guimard, Thomas, Suaud, Isabelle, Girard, Jean-Jacques, Simonet, Véronique, Debab, Yasmine, Schmit, Jean-Luc, Jacomet, Christine, Weinberck, Pierre, Genet, Claire, Pinet, Pauline, Ducroix, Sophie, Durox, Hélène, Denes, Éric, Abraham, Bruno, Gourdon, Florence, Antoniotti, Odile, Molina, Jean-Michel, Ferret, Samuel, Lascoux-Combe, Caroline, Lafaurie, Matthieu, Colin de Verdiere, Nathalie, Ponscarme, Diane, De Castro, Nathalie, Aslan, Alexandre, Rozenbaum, Willy, Pintado, Claire, Clavel, François, Taulera, Olivier, Gatey, Caroline, Munier, Anne-Lise, Gazaigne, Sandrine, Penot, Pauline, Conort, Guillaume, Lerolle, Nathalie, Leplatois, Anne, Balausine, Stéphanie, Delgado, Jeannine, Timsit, Julie, Tabet, Magda, Gerard, Laurence, Girard, Pierre-Marie, Picard, Odile, Tredup, Jürgen, Bollens, Diane, Valin, Nadia, Campa, Pauline, Bottero, Julie, Lefebvre, Benedicte, Tourneur, Muriel, Fonquernie, Laurent, Wemmert, Charlotte, Lagneau, Jean-Luc, Yazdanpanah, Yazdan, Phung, Bao, Pinto, Adriana, Vallois, Dorothée, Cabras, Ornella, Louni, Françoise, Pialoux, Gilles, Lyavanc, Thomas, Berrebi, Valérie, Chas, Julie, Lenagat, Sophie, Rami, Agathe, Diemer, Myriam, Parrinello, Maguy, Depond, Audrey, Salmon, Dominique, Guillevin, Loïc, Tahi, Tassadit, Belarbi, Linda, Loulergue, Pierre, Zak Dit Zbar, Olivier, Launay, Odile, Silbermann, Benjamin, Leport, Catherine, Alagna, Laura, Pietri, Marie-Pierre, Simon, Anne, Bonmarchand, Manuela, Amirat, Naouel, Pichon, François, Kirstetter, Myriam, Katlama, Christine, Valantin, Marc Antoine, Tubiana, Roland, Caby, Fabienne, Schneider, Luminita, Ktorza, Nadine, Calin, Ruxandra, Merlet, Audrey, Ben Abdallah, Saadia, Weiss, Laurence, Buisson, Martin, Batisse, Dominique, Karmochine, Marina, Pavie, Juliette, Minozzi, Catherine, Jayle, Didier, Castel, Philippe, Derouineau, Jean, Kousignan, Pascale, Eliazevitch, Murielle, Pierre, Isabelle, Collias, Lio, Viard, Jean-Paul, Gilquin, Jacques, Sobel, Alain, Slama, Laurence, Ghosn, Jade, Hadacek, Blanka, Thu-Huyn, Nugyen, Nait-Ighil, Lella, Cros, Agnes, Maignan, Aline, Duvivier, Claudine, Consigny, Paul Henri, Lanternier, Fanny, Shoai-Tehrani, Michka, Touam, Fatima, Jerbi, Saadia, Bodard, Loïc, Jung, Corinne, Goujard, Cécile, Quertainmont, Yann, Duracinsky, Martin, Segeral, Olivier, Blanc, Arnaud, Peretti, Delphine, Cheret, Antoine, Chantalat, Christelle, Dulucq, Marie Josée, Levy, Yves, Lelievre, Jean Daniel, Lascaux, Anne Sophie, Dumont, Cécile, Boue, François, Chambrin, Véronique, Abgrall, Sophie, Kansau, Imad, Raho-Moussa, Mariem, De Truchis, Pierre, Dinh, Aurélien, Davido, Benjamin, Marigot, Dhiba, Berthe, Huguette, Devidas, Alain, Chevojon, Pierre, Chabrol, Amélie, Agher, Nouara, Lemercier, Yvon, Chaix, Fabrice, Turpault, Isabelle, Bouchaud, Olivier, Honore, Patricia, Rouveix, Elisabeth, Reimann, Evelyne, Belan, Alix Greder, Godin Collet, Claire, Souak, Safia, Mortier, Emmanuel, Bloch, Martine, Simonpoli, Anne-Marie, Manceron, Véronique, Cahitte, Isabelle, Hiraux, Emmanuel, Lafon, Erik, Cordonnier, François, Zeng, Ai-Feng, Zucman, David, Majerholc, Catherine, Bornarel, Dominique, Uludag, Agnès, Gellen-Dautremer, Justine, Lefort, Agnès, Bazin, Christine, Daneluzzi, Vincent, Gerbe, Juliette, Jeantils, Vincent, Coupard, Mélissa, Patey, Olivier, Bantsimba, Jonas, Delllion, Sophie, Paz, Pauline Caraux, Cazenave, Benoit, Richier, Laurent, Garrait, Valérie, Delacroix, Isabelle, Elharrar, Brigitte, Vittecoq, Daniel, Bolliot, Claudine, Lepretre, Annie, Genet, Philippe, Masse, Virginie, Perrone, Véronique, Boussard, Jean-Luc, Chardon, Patricia, Froguel, Eric, Simon, Philippe, Tassi, Sylvie, Avettand Fenoel, Véronique, Barin, Francis, Bourgeois, Christine, Cardon, Fanny, Chaix, Marie-Laure, Delfraissy, Jean François, Essat, Asma, Fischer, Hugues, Lecuroux, Camille, Petrov-Sanchez, Ventzislava, Rouzioux, Christine, Saez-Cirion, Asier, Seng, Rémonie, Kuldanek, Kristin, Mullaney, Scott, Young, Carmel, Zucchetti, Antonella, Bevan, Margaret-Ann, McKernan, Sinead, Wandolo, Emily, Richardson, Celia, Youssef, Elaney, Green, Pippa, Faulkner, Sue, Faville, Rebecca, Herman, Sandra, Care, Christine, Blackman, Helen, Bellenger, Katharine, Fairbrother, Keith, Phillips, Andrew, Babiker, Abdel, Delpech, Valerie, Fidler, S, Clarke, Mindy, Fox, Julie, Gilson, R, Goldberg, David, Hawkins, David, Johnson, Anne, Johnson, Margaret, McLean, Ken, Nastouli, Eleni, Post, Frank, Kennedy, N, Pritchard, J, Andrady, U, Rajda, N, Donnelly, C, McKernan, S, Drake, S, Gilleran, G, White, D, Ross, J, Harding, J, Faville, R, Sweeney, J, Flegg, P, Toomer, S, Wilding, H, Woodward, R, Dean, G, Richardson, C, Perry, N, Gompels, M, Jennings, L, Bansaal, D, Browing, M, Connolly, L, Stanley, B, Estreich, S, Magdy, A, O'Mahony, C, Fraser, P, Jebakumar, S P R, David, L, Mette, R, Summerfield, H, Evans, M, White, C, Robertson, R, Lean, C, Morris, S, Winter, A, Faulkner, S, Goorney, B, Howard, L, Fairley, I, Stemp, C, Short, L, Gomez, M, Young, F, Roberts, M, Green, S, Sivakumar, K, Minton, J, Siminoni, A, Calderwood, J, Greenhough, D, DeSouza, C, Muthern, Lisa, Orkin, C, Murphy, S, Truvedi, M, McLean, K, Hawkins, D, Higgs, C, Moyes, A, Antonucci, S, McCormack, S, Lynn, W, Bevan, M, Fox, J, Teague, A, Anderson, J, Mguni, S, Post, F, Campbell, L, Mazhude, C, Russell, H, Carrick, G, Ainsworth, J, Waters, A, Byrne, P, Johnson, M, Kuldanek, K, Mullaney, S, Lawlor, V, Melville, R, Sukthankar, A, Thorpe, S, Murphy, C, Wilkins, E, Ahmad, S, Green, P, Tayal, S, Ong, E, Meaden, J, Riddell, L, Loay, D, Peacock, K, Blackman, H, Harindra, V, Saeed, A M, Allen, S, Natarajan, U, Williams, O, Lacey, H, Care, C, Bowman, C, Herman, S, Devendra, S V, Wither, J, Bridgwood, A, Singh, G, Bushby, S, Kellock, D, Young, S, Rooney, G, Snart, B, Currie, J, Fitzgerald, M, Arumainayyagam, J, Chandramani, S, Rajamanoharan, S, Robinson, T, Taylor, B, Brewer, C, Mayr, Christoph, Schmidt, Wolfgang, Speidel, Andrea, Strohbach, Frank, Arastéh, Keikawus, Cordes, Christiane, Stündel, Manfred, Claus, Jörg, Baumgarten, Axel, Carganico, Andreas, Ingiliz, Patrick, Dupke, Stephan, Freiwald, Matthias, Rausch, Michael, Moll, Arend, Schleehauf, Dorothea, Hintsche, Bettina, Klausen, Gerd, Jessen, Heiko, Jessen, Arne, Köppe, Siegfried, Kreckel, Peter, Schranz, Dietmar, Fischer, Klaus, Schulbin, Hubert, Speer, Miriam, Glaunsinger, Tobias, Wicke, Thomas, Bieniek, Bernhard, Hillenbrand, Heribert, Schlote, Frank, Lauenroth-Mai, Elke, Schuler, Christoph, Schürmann, Dirk, Wesselmann, Hans, Brockmeyer, Norbert, Gehring, Peter, Schmalöer, Dirk, Hower, Martin, Spornraft-Ragaller, Petra, Häussinger, Dieter, Reuter, Stefan, Esser, Stefan, Markus, Rudolf, Kreft, Burkhard, Berzow, Dirk, Christl, Andreas, Meyer, Andreas, Plettenberg, Andreas, Stoehr, Albrecht, Graefe, Katrin, Lorenzen, Thore, Adam, Axel, Schewe, Knut, Weitner, Lutwin, Fenske, Stefan, Hansen, Stefan, Stellbrink, Hans-Jürgen, Wiemer, Dorothea, Hertling, Sandra, Schmidt, Reinhold, Arbter, Peter, Claus, Bernd, Galle, Peter, Jäger, Hans, Jä Gel-Guedes, Eva, Postel, Nils, Fröschl, Monika, Spinner, Christoph, Bogner, Johannes, Salzberger, Bernd, Schölmerich, Jürgen, Audebert, Franz, Marquardt, Ties, Schaffert, Andreas, Schnaitmann, Eiko, Trein, Andreas, Frietsch, Bernhard, Müller, Marcus, Ulmer, Albrecht, Detering-Hübner, Barbara, Kern, Peter, Schubert, Franz, Dehn, Günther, Schreiber, Maria, Güler, Cengiz, Schmidt, Daniel, Meixenberger, Karolin, Medical Microbiology & Infectious Diseases, Internal Medicine, Virology, Pediatrics, Medical Microbiology and Infection Prevention, AII - Infectious diseases, Global Health, Infectious diseases, APH - Aging & Later Life, Centre interdisciplinaire de recherche en biologie (CIRB), Labex MemoLife, École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Collège de France (CdF (institution))-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Internal medicine, VU University medical center, Surgery, AMS - Rehabilitation & Development, APH - Quality of Care, Psychiatry, Pediatric surgery, Neurology, Public and occupational health, APH - Mental Health, Pathology, Cardiology, ACS - Heart failure & arrhythmias, Anesthesiology, IOO, Rehabilitation medicine, Obstetrics and gynaecology, General practice, Gastroenterology and hepatology, Pulmonary medicine, ACS - Pulmonary hypertension & thrombosis, Medical oncology laboratory, Hematology, Epidemiology and Data Science, Physiology, Microbes in Health and Disease (MHD), University of Oxford, Stichting HIV Monitoring [Amsterdam], Universiteit van Amsterdam (UvA), European Bioinformatics Institute [Hinxton] (EMBL-EBI), EMBL Heidelberg, Amsterdam UMC - Amsterdam University Medical Center, The Wellcome Trust Sanger Institute [Cambridge], Karolinska Institutet [Stockholm], Robert Koch Institute [Berlin] (RKI), Ecole Polytechnique Fédérale de Lausanne (EPFL), Johns Hopkins University (JHU), Universität Zürich [Zürich] = University of Zurich (UZH), Helsinki University Hospital [Helsinki, Finlande], Helsingin yliopisto = Helsingfors universitet = University of Helsinki, National Institute of Allergy and Infectious Diseases [Bethesda] (NIAID-NIH), National Institutes of Health [Bethesda] (NIH), Centre de recherche en épidémiologie et santé des populations (CESP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, University College of London [London] (UCL), Kymab Ltd, Cambridge, England, Institut Pasteur [Paris] (IP), This study was funded by ERC Advanced Grant PBDR-339251 and a Li Ka Shing Foundation grant, both awarded to C.F. The ATHENA Cohort is managed by Stichting HIV Monitoring and supported by a grant from the Dutch Ministry of Health, Welfare and Sport through the Centre for Infectious Disease Control of the National Institute for Public Health and the Environment., We thank K. Fransen and G. Vanham for help with the Belgian data, O. Ratmann for help in identifying the Dutch clusters, K. Kusejko for testing for additional VB individuals in the SHCS, B. Foley for help with genome sharing, B. Dearlove and L. Thomson for help with software, and J. Herbeck and three other reviewers for helpful suggestions., Contributors and affiliations are listed in the supplementary materials., Department of Medicine, University of Helsinki, Infektiosairauksien yksikkö, HUS Inflammation Center, and Clinicum
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Adult ,Male ,HIV-1/genetics ,Genotype ,Anti-HIV Agents ,Evolution ,[SDV]Life Sciences [q-bio] ,lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4] ,HIV Infections/drug therapy ,selection ,HIV Infections ,Genome, Viral ,heritability ,epidemic ,human-immunodeficiency-virus ,Evolution, Molecular ,SDG 3 - Good Health and Well-being ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Humans ,Viral ,Phylogeny ,Netherlands ,Multidisciplinary ,Genome ,model ,Virulence ,transmission ,Molecular ,setpoint viral load ,reverse-transcriptase ,dynamics ,Viral Load ,CD4 Lymphocyte Count ,lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] ,3121 General medicine, internal medicine and other clinical medicine ,Anti-HIV Agents/therapeutic use ,Mutation ,HIV-1 ,Female ,progression - Abstract
Comment in Does HIV-1 virulence matter in the ART era? Lewitus E, Rolland M. Med (N Y). 2022 Apr 8;3(4):217-219. doi: 10.1016/j.medj.2022.03.003. PMID: 35590149; International audience; We discovered a highly virulent variant of subtype-B HIV-1 in the Netherlands. One hundred nine individuals with this variant had a 0.54 to 0.74 log 10 increase (i.e., a ~3.5-fold to 5.5-fold increase) in viral load compared with, and exhibited CD4 cell decline twice as fast as, 6604 individuals with other subtype-B strains. Without treatment, advanced HIV—CD4 cell counts below 350 cells per cubic millimeter, with long-term clinical consequences—is expected to be reached, on average, 9 months after diagnosis for individuals in their thirties with this variant. Age, sex, suspected mode of transmission, and place of birth for the aforementioned 109 individuals were typical for HIV-positive people in the Netherlands, which suggests that the increased virulence is attributable to the viral strain. Genetic sequence analysis suggests that this variant arose in the 1990s from de novo mutation, not recombination, with increased transmissibility and an unfamiliar molecular mechanism of virulence.
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- 2022
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22. Influence of geographic origin, sex, and HIV transmission group on the outcome of first-line combined antiretroviral therapy in France
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de Monteynard, Laure-Amélie, Matheron, Sophie, Gilquin, Jacques, Pavie, Juliette, de Truchis, Pierre, Grabar, Sophie, Launay, Odile, Meynard, Jean-Luc, Khuong-Josses, Marie-Aude, Rey, David, Simon, Anne, Mahamat, Aba, Dray-Spira, Rosemary, Costagliola, Dominique, and Abgrall, Sophie
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- 2016
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23. Didanosine in HIV-1-Infected Patients Experiencing Failure of Antiretroviral Therapy: A Randomized Placebo-Controlled Trial
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AI454-176 JAGUAR Study Team, Molina, Jean-Michel, Marcelin, Anne-Geneviève, Pavie, Juliette, Heripret, Laurence, Boever, Corinne Merle De, Troccaz, Marline, Leleu, Ghislaine, and Calvez, Vincent
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- 2005
24. A 4-days-on and 3-days-off maintenance treatment strategy for adults with HIV-1 (ANRS 170 QUATUOR): a randomised, open-label, multicentre, parallel, non-inferiority trial
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Landman, Roland, primary, de Truchis, Pierre, additional, Assoumou, Lambert, additional, Lambert, Sidonie, additional, Bellet, Jonathan, additional, Amat, Karine, additional, Lefebvre, Bénédicte, additional, Allavena, Clotilde, additional, Katlama, Christine, additional, Yazdanpanah, Yazdan, additional, Molina, Jean-Michel, additional, Petrov-Sanchez, Ventzislava, additional, Gibowski, Séverine, additional, Alvarez, Jean-Claude, additional, Leibowitch, Jacques, additional, Capeau, Jacqueline, additional, Fellahi, Soraya, additional, Duracinsky, Martin, additional, Morand-Joubert, Laurence, additional, Costagliola, Dominique, additional, Girard, Pierre-Marie, additional, LAMAURY, Isabelle, additional, BANI-SADR, Firouzé, additional, FORCE, Gilles, additional, CHABROL, Amélie, additional, CABY, Fabienne, additional, PATEY, Olivier, additional, FRESARD, Anne, additional, GAGNEUX-BRUNON, Amandine, additional, CHIROUZE, Catherine, additional, DUVIVIER, Claudine, additional, LOURENCO, Jérémie, additional, TOLSMA, Violaine, additional, JANSSEN, Cécile, additional, LEROLLE, Nathalie, additional, CATALAN, Pilartxo, additional, RAMI, Agathe, additional, DE PONTHAUD, Lucile, additional, PICHANCOURT, Gilles, additional, NASRI, Safa, additional, LANDOWSKI, Stéphanie, additional, BOTTERO, Julie, additional, MFUTILA KAYKAY, Flory, additional, PIALOUX, Gilles, additional, BOUCHAUD, Olivier, additional, ABGRALL, Sophie, additional, GATEY, Caroline, additional, WEISS, Laurence, additional, PAVIE, Juliette, additional, SALMON-CERON, Dominique, additional, ZUCMAN, David, additional, LELIEVRE, Jean-Daniel, additional, PALICH, Romain, additional, SIMON, Anne, additional, MEYOHAS, Marie-Caroline, additional, GRAS, Julien, additional, CABIE, André, additional, PIRCHER, Mathilde, additional, MORLAT, Philippe, additional, HESSAMFAR, Mojgam, additional, NEAU, Didier, additional, CAZENAVE, Charles, additional, GENET, Claire, additional, FAUCHER, Jean-François, additional, MAKHLOUFI, Djamila, additional, BOIBIEUX, André, additional, BREGIGEON-RONOT, Sylvie, additional, LAROCHE, Hélène, additional, SAUTEREAU, Aurélie, additional, REYNES, Jacques, additional, MAKINSON, Alain, additional, RAFFI, François, additional, BOLLENGIER-STRAGIER, Olivier, additional, NAQVI, Alissa, additional, CUA, Eric, additional, ROSENTHAL, Eric, additional, ARVIEUX, Cédrick, additional, BUZELE, Rodolphe, additional, REY, David, additional, BATARD, Marie-Laure, additional, BERNARD, Louis, additional, DELOBEL, Pierre, additional, PIFFAUT, Marie, additional, VERDON, Renaud, additional, PIROTH, Lionel, additional, BLOT, Mathieu, additional, LECLERCQ, Pascale, additional, SIGNORI-SCHMUCK, Anne, additional, HULEUX, Thomas, additional, MEYBECK, Agnès, additional, MAY, Thierry, additional, MIAILHES, Patrick, additional, PERPOINT, Thomas, additional, GREDER-BELAN, Alix, additional, ELHARRAR, Brigitte, additional, KHUONG, Marie-Aude, additional, POUPARD, Marie, additional, BLUM, Laurent, additional, MICHAU, Christophe, additional, PRAZUCK, Thierry, additional, PHILIBERT, Patrick, additional, SLAMA, Laurence, additional, HIKOMBO, Hitoto, additional, DARASTEANU, Iuliana, additional, GIRARD, Pierre-Marie, additional, ALVAREZ, Jean-Claude, additional, MATHEZ, Dominique, additional, DE TRUCHIS, Pierre, additional, LANDMAN, Roland, additional, MEYNARD, Jean-Luc, additional, MORAND-JOUBERT, Laurence, additional, LAMBERT, Sidonie, additional, LE DU, Damien, additional, PERRONNE, Christian, additional, ASSOUMOU, Lambert, additional, COSTAGLIOLA, Dominique, additional, MELCHIOR, Jean-Claude, additional, DURACINSKI, Martin, additional, PETROV-SANCHEZ, Ventzislava, additional, AMAT, Karine, additional, BENALYCHERIF, Aïda, additional, SYLLA, Babacar, additional, GELLEY, Ambre, additional, GIBOWSKI, Séverine, additional, LE MEUT, Guillaume, additional, THIEBAUT, Rodolphe, additional, CLUMECK, Nathan, additional, LECLERCQ, Vincent, additional, CECCHERINI-SILBERSTEIN, Francesca, additional, and DECOSTER, Laurent, additional
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- 2022
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25. Striking Differences in Weight Gain after Cart Initiation Depending on Early or Late Presentation: Results from the ANRS CO4 FHDH Cohort
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Grabar, Sophie, primary, Potard, Valérie, additional, Piroth, Lionel, additional, Abgrall, Sophie, additional, Bernard, Louis, additional, Allavena, Clothilde, additional, Caby, Fabienne, additional, de Truchis, Pierre, additional, Duvivier, Claudine, additional, Enel, Patricia, additional, Katlama, Christine, additional, KHUONG, Marie-Aude, additional, Launay, Odile, additional, Matheron, Sophie, additional, Melica, Giovanna, additional, Melliez, Hughes, additional, Meynard, Jean-Luc, additional, Pavie, Juliette, additional, Slama, Laurence, additional, Bregigeon-Ronot, Sylvie, additional, Tattevin, Pierre, additional, Capeau, Jacqueline, additional, and Costagliola, Dominique, additional
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- 2022
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26. Clinical, virological and imaging profile in patients with prolonged forms of COVID-19: A cross-sectional study
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Salmon-Ceron, Dominique, Slama, Dorsaf, De Broucker, Thomas, Karmochkine, Marina, Pavie, Juliette, Sorbets, Emmanuel, Etienne, Nicolas, Batisse, Dominique, Spiridon, Gabriela, Baut, Valérie Le, Meritet, Jean-François, Pichard, Eric, and Canouï-Poitrine, Florence
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- 2021
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27. Cohort Profile: French hospital database on HIV (FHDH-ANRS CO4)
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Mary-Krause, Murielle, Grabar, Sophie, Lièvre, Laurence, Abgrall, Sophie, Billaud, Eric, Boué, François, Boyer, Laurence, Cabié, André, Cotte, Laurent, De Truchis, Pierre, Duval, Xavier, Duvivier, Claudine, Enel, Patricia, Gasnault, Jacques, Gaud, Catherine, Gilquin, Jacques, Guiguet, Marguerite, Katlama, Christine, Khuong-Josses, Marie-Aude, Lacombe, Jean-Marc, Lang, Sylvie, Lascaux, Anne-Sophie, Launay, Odile, Mahamat, Aba, Matheron, Sophie, Meynard, Jean-Luc, Pavie, Juliette, Pilorgé, Fabrice, Piroth, Lionel, Poizot-Martin, Isabelle, Potard, Valérie, Pradier, Christian, Reynes, Jacques, Rouveix, Elisabeth, Selinger-Leneman, Hana, Simon, Anne, Tattevin, Pierre, Tissot-Dupont, Hervé, Viard, Jean-Paul, Viget, Nathalie, and Costagliola, Dominique
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- 2014
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28. Etiologies and diagnostic work-up of extreme macrocytosis defined by an erythrocyte mean corpuscular volume over 130°fL: A study of 109 patients
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Planche, Virginie, Georgin-Lavialle, Sophie, Avillach, Paul, Ranque, Brigitte, Pavie, Juliette, Caruba, Thibaut, Darnige, Luc, and Pouchot, Jacques
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- 2014
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29. Etiologies and outcome of acute respiratory failure in HIV-infected patients
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Barbier, François, Coquet, Isaline, Legriel, Stéphane, Pavie, Juliette, Darmon, Michael, Mayaux, Julien, Molina, Jean-Michel, Schlemmer, Benoît, and Azoulay, Élie
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- 2009
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30. Additional file 1 of Missed opportunities for HIV testing in patients newly diagnosed with HIV in Morocco
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Marih, Latifa, Sawras, Victoire, Pavie, Juliette, Sodqi, Mustapha, Malmoussi, Mourad, Tassi, Noura, Rajaa Bensghir, Nani, Samira, Ahd Oulad Lahsen, Laureillard, Didier, Filali, Kamal Marhoum El, Champenois, Karen, and Weiss, Laurence
- Abstract
Additional file 1: Fig. S1. Distribution of HIV/AIDS cases in Morocco by region, 2005–2009.
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- 2021
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31. Additional file 2 of Missed opportunities for HIV testing in patients newly diagnosed with HIV in Morocco
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Marih, Latifa, Sawras, Victoire, Pavie, Juliette, Sodqi, Mustapha, Malmoussi, Mourad, Tassi, Noura, Rajaa Bensghir, Nani, Samira, Ahd Oulad Lahsen, Laureillard, Didier, Filali, Kamal Marhoum El, Champenois, Karen, and Weiss, Laurence
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virus diseases - Abstract
Additional file 2: Fig. S2. Characteristics of patients who sought care for a clinical indicator in the three years prior to HIV diagnosis according to whether or not (missed opportunity) the care provider offered them an HIV test (n = 252).
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- 2021
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32. Evaluation of saliva molecular point of care for detection of SARS-CoV-2 in ambulatory care
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LeGoff, Jérôme, primary, Kernéis, Solen, additional, Elie, Caroline, additional, Delarue, Séverine Mercier, additional, Gastli, Nabil, additional, Choupeaux, Laure, additional, Fourgeaud, Jacques, additional, Alby, Marie-Laure, additional, Quentin, Pierre, additional, Pavie, Juliette, additional, Brazille, Patricia, additional, Néré, Marie Laure, additional, Minier, Marine, additional, Gabassi, Audrey, additional, Leroy, Chrystel, additional, Parfait, Béatrice, additional, Tréluyer, Jean-Marc, additional, and Delaugerre, Constance, additional
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- 2021
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33. Accuracy of antigen and nucleic acid amplification testing on saliva and naopharyngeal samples for detection of SARS-CoV-2 in ambulatory care
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Kernéis, Solen, primary, Elie, Caroline, additional, Fourgeaud, Jacques, additional, Choupeaux, Laure, additional, Delarue, Séverine Mercier, additional, Alby, Marie-Laure, additional, Quentin, Pierre, additional, Pavie, Juliette, additional, Brazille, Patricia, additional, Néré, Marie Laure, additional, Minier, Marine, additional, Gabassi, Audrey, additional, Gibaud, Aurélien, additional, Gauthier, Sébastien, additional, Leroy, Chrystel, additional, Voirin-Mathieu, Etienne, additional, Poyart, Claire, additional, Vidaud, Michel, additional, Parfait, Béatrice, additional, Delaugerre, Constance, additional, Tréluyer, Jean-Marc, additional, and Le Goff, Jérôme, additional
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- 2021
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34. Quality of Travel Health Advice in a French Travel Medicine and Vaccine Center: A Prospective Observational Study
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Bouldouyre, Marie-Anne, De Verdière, Nathalie Colin, Pavie, Juliette, De Castro, Nathalie, Ponscarme, Diane, Hamane, Samia, Rachline, Anne, Ferret, Samuel, and Molina, Jean-Michel
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- 2012
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35. Efficacy and safety of a switch to unboosted atazanavir in combination with nucleoside analogues in HIV-1-infected patients with virological suppression under antiretroviral therapy
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Pavie, Juliette, Porcher, Raphael, Torti, Carlo, Medrano, José, Castagna, Antonella, Valin, Nadia, Rusconi, Stefano, Ammassari, Adriana, Ghosn, Jade, Delaugerre, Constance, Molina, Jean-Michel, Franzetti, Marco, Lascoux-Combes, Caroline, Lorenzini, Patrizia, Carosi, Giampiero, Albini, Laura, Nasta, Paola, Quiros-Roldan, Eugenia, Castelnuovo, Filippo, and Rachline, Anne
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- 2011
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36. HPV-circulating tumoural DNA by droplet-based digital polymerase chain reaction, a new molecular tool for early detection of HPV metastatic anal cancer? A case report
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Veyer, David, Pavie, Juliette, Pernot, Simon, Mandavit, Marion, Garrigou, Sonia, Lucas, Marie-Laure, Gibault, Laure, Taly, Valérie, Weiss, Laurence, and Péré, Hélène
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- 2019
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37. Severe Acute Renal Failure in an HIV-Infected Patient After Only 2 Weeks of Tenofovir-Based Antiretroviral Therapy
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Pavie, Juliette, Scemla, Anne, Bouldouyre, Marie Anne, Pillebout, Evangéline, Verine, Jérome, and Molina, Jean Michel
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- 2011
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38. Risk of Severe Bacterial Infection in People Living Human Immunodeficiency Virus Infection in the Combined Antiretroviral Therapy Era
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Melliez, Hugues, primary, Mary-Krause, Murielle, additional, Guiguet, Marguerite, additional, Carrieri, Patrizia, additional, Abgrall, Sophie, additional, Enel, Patricia, additional, Gallien, Sébastien, additional, Duval, Xavier, additional, Duvivier, Claudine, additional, Pavie, Juliette, additional, Siguier, Martin, additional, Freire-Maresca, Anaenza, additional, Tattevin, Pierre, additional, and Costagliola, Dominique, additional
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- 2020
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39. Impact on Health-Related Quality of Life of a Switch From Enfuvirtide to Raltegravir Among Multidrug-Resistant HIV-1-Infected Patients: A Randomized Open-Label Trial (EASIER-ANRS 138)
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Boulet, Thomas, Pavie, Juliette, Charreau, Isabelle, Braun, Joséphine, Reynes, Jacques, Morlat, Philippe, Piroth, Lionel, Spire, Bruno, Molina, Jean-Michel, and Aboulker, Jean-Pierre
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- 2010
40. Restoration of Toxoplasma gondii-specific immune responses in patients with AIDS starting HAART
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Furco, André, Carmagnat, Maryvonnick, Chevret, Sylvie, Garin, Yves J-F, Pavie, Juliette, De Castro, Nathalie, Charron, Dominique, Derouin, Francis, Rabian, Claire, and Molina, Jean-Michel
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- 2008
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41. Pattern and impact of emerging resistance mutations in treatment experienced patients failing darunavir-containing regimen
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Delaugerre, Constance, Pavie, Juliette, Palmer, Pierre, Ghosn, Jade, Blanche, Stephane, Roudiere, Laurent, Dominguez, Stephanie, Mortier, Emmanuel, Molina, Jean-Michel, and de Truchis, Pierre
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- 2008
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42. Comparative Immunovirological and Clinical Responses to Antiretroviral Therapy Between HIV-1 Group O and HIV-1 Group M Infected Patients
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Kouanfack, Charles, Unal, Guillemette, Schaeffer, Laura, Kfutwah, Anfumbom, Aghokeng, Avelin, Mougnutou, Rose, Tchemgui-Noumsi, Nathalie, Alessandri-Gradt, Elodie, Delaporte, Eric, Simon, Francois, Vray, Muriel, Plantier, Jean-Christophe, Alima, Michèle, Essengué, Lucie, Mounpou, Georges, Ngang, Peter, Ngoma, Pauline, Omgba, Vincent, Omam, Deborah, Tonfack, Léonie, Zé, Flore, Akongnwi, Emmanuel, Dumortier, Jérôme, Ngoupo, Paul-Alain, Njouom, Richard, Rousset, Dominique, Vessière, Aurélia, Fouler, Lenaig Le, Madec, Yoann, Bodelet, Marine, Dupre, Jean-Michel, Pavie, Juliette, Rekacewicz, Claire, Garcia, Paula, Colin, Géraldine, Hôpital Central de Yaoundé [Yaoundé], Groupe de Recherche sur l'Adaptation Microbienne (GRAM 2.0), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Université de Rouen Normandie (UNIROUEN), Normandie Université (NU), Laboratoire de virologie [Rouen], Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU)-CHU Rouen, Epidémiologie des Maladies Emergentes - Emerging Diseases Epidemiology, Pasteur-Cnam Risques infectieux et émergents (PACRI), Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Institut Pasteur [Paris] (IP)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM), Centre Pasteur du Cameroun, Réseau International des Instituts Pasteur (RIIP), Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques et émergentes (TransVIHMI), Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Hopital Saint-Louis [AP-HP] (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7), DynaMo study group, Institut Pasteur [Paris] (IP), Agence Nationale de Recherches sur le Sida et les Hépatites Virales (ANRS), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-Département de microbiologie : Bactério, Virologie, Parasito, Hygiène-Hôpital Charles Nicolle [Rouen]-CHU Rouen, Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques er émergentes (TransVIHMI), Université Montpellier 1 (UM1)-Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Hôpital Charles Nicolle [Rouen]-CHU Rouen, Normandie Université (NU)-Département de microbiologie : Bactério, Virologie, Parasito, Hygiène, Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université (HESAM)-HESAM Université (HESAM)-Institut Pasteur [Paris]-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université (HESAM)-HESAM Université (HESAM), and Institut Pasteur [Paris]
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0301 basic medicine ,Microbiology (medical) ,Cart ,medicine.medical_specialty ,Anti-HIV Agents ,immuno-virological response ,030106 microbiology ,HIV-1 group O ,Human immunodeficiency virus (HIV) ,HIV Infections ,cART ,medicine.disease_cause ,[SDV.MP.PRO]Life Sciences [q-bio]/Microbiology and Parasitology/Protistology ,Gastroenterology ,immunovirological response ,03 medical and health sciences ,Antiretroviral Therapy, Highly Active ,Internal medicine ,medicine ,Clinical endpoint ,Humans ,Protease inhibitor (pharmacology) ,[SDV.MP.MYC]Life Sciences [q-bio]/Microbiology and Parasitology/Mycology ,Ritonavir ,business.industry ,virus diseases ,genetic diversity ,Viral Load ,[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology ,Antiretroviral therapy ,Pathophysiology ,CD4 Lymphocyte Count ,3. Good health ,Clinical trial ,030104 developmental biology ,Infectious Diseases ,Anti-Retroviral Agents ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,HIV-1 ,MESH: HIV-1 group O ,Drug Therapy, Combination ,Panton–Valentine leukocidin ,business - Abstract
BackgroundLittle is known about impact of genetic divergence of human immunodeficiency virus type 1 group O (HIV-1/O) relative to HIV-1 group M (HIV-1/M) on therapeutic outcomes. We aimed to determine if responses to standardized combination antiretroviral therapy (cART) were similar between groups despite strain divergence.MethodsWe performed an open nonrandomized study comparing the immunological, virological, and clinical responses to cART based on 2 nucleoside reverse transcriptase inhibitors plus 1 ritonavir-boosted protease inhibitor, in naive and paired HIV-1/O vs HIV-1/M infected (+) patients (ratio 1:2), matched on several criteria. The primary endpoint was the proportion of patients with undetectable plasma viral load (pVL, threshold 60 copies/mL) at week (W) 48. Secondary endpoints were the proportion of patients with undetectable pVL at W24 and W96 and CD4 evolution between baseline and W24, W48, and W96.ResultsForty-seven HIV-1/O+ and 94 HIV-1/M+ patients were included. Mean pVL at baseline was significantly lower by 1 log for HIV-1/O+ vs HIV-1/M+ patients. At W48, no significant difference was observed between populations with undetectable pVL and differences at W24 and W96 were not significant. A difference in CD4 gain was observed in favor of HIV-1/M at W48 and W96, but this was not significant when adjusted on both matched criteria and pVL at baseline.ConclusionsOur data demonstrate similar immunovirological and clinical response between HIV-1/O+ and HIV-1/M+ patients. They also reveal significantly lower baseline replication for HIV-1/O variants, suggesting specific virological properties and physiopathology that now need to be addressed.Clinical Trials RegistrationNCT00658346.
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- 2019
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43. Didanosine in HIV-1-infected patients experiencing failure of antiretroviral therapy: a randomized placebo-controlled trial
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Molina, Jean-Michel, Marcelin, Anne-Genevieve, Pavie, Juliette, Heripret, Laurence, De Boever, Corinne Merle, Troccaz, Martine, Leleu, Ghislaine, and Calvez, Vincent
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Didanosine -- Dosage and administration ,Didanosine -- Research ,Antiviral agents -- Dosage and administration ,Health - Published
- 2005
44. Successful Treatment of Pulmonary Mucormycosis in an Allogenic Bone-marrow Transplant Recipient with Combined Medical and Surgical Therapy
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Pavie, JULIETTE, Lafaurie, MATTHIEU, Lacroix, CLAIRE, Zagdanski, ANNE Marie, Debrosse, DENIS, Socié, GÉRARD, Derouin, FRANCIS, Gluckman, ELIANE, and Molina, JEAN Michel
- Published
- 2004
45. Papillomavirus, et si on parlait cancer et prévention ?
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Pernot, Simon, primary, Pavie, Juliette, additional, Péré, Hélène, additional, Menard, Madeleine, additional, Hurel, Sophie, additional, Cochand-Priollet, Beatrix, additional, Bats, Anne-Sophie, additional, and Badoual, Cécile, additional
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- 2018
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46. Traitement de l’infection par le virus de l’immunodéficience humaine en 2005 chez l’adulte
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Pavie, Juliette and Molina, Jean-Michel
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- 2005
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47. Interruptions du traitement antirétroviral chez 30 patients infectés par le VIH en succès virologique
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Pavie, Juliette, Porcher, Raphaël, Fournier, Sandra, Furco, André, Tournoux, Caroline, Palmer, Pierre, Rabian, Claire, and Molina, Jean-Michel
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- 2005
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48. Influence of geographic origin on AIDS and serious non-AIDS morbidity/mortality during cART among heterosexual HIV-infected men and women in France.
- Author
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de Monteynard, Laure-Amélie, Matheron, Sophie, Grabar, Sophie, de Truchis, Pierre, Gilquin, Jacques, Pavie, Juliette, Launay, Odile, Meynard, Jean-Luc, Khuong-Josses, Marie-Aude, Rey, David, Mahamat, Aba, Dray-Spira, Rosemarie, Simon, Anne, Costagliola, Dominique, Abgrall, Sophie, and null, null
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AIDS ,HETEROSEXUAL men ,HIV-positive persons ,MEDICAL statistics - Abstract
Background: The influence of geographic origin on the risk of severe illness and death on cART has not been explored in European countries. Method: We studied antiretroviral-naïve heterosexual HIV-1-infected individuals enrolled in the FHDH-ANRS CO4 cohort in France who started cART between 2006 and 2011. Individuals originating from France (French natives), sub-Saharan Africa (SSA) and non-French West-Indies (NFW) were studied until 2012. Crude and adjusted rate ratios (aRR) of severe morbid events/deaths (AIDS-related and non-AIDS-related) were calculated using Poisson regression models stratified by sex, comparing each group of migrants to French natives. Results: Among 2334 eligible men, 1379 (59.1%) originated from France, 838 (35.9%) from SSA and 117 (5.0%) from NFW. SSA male migrants had a higher aRR for non-AIDS infections, particularly bacterial infections (aRR 1.56 (95% CI 1.07–2.29), p = 0.0477), than French natives. Among 2596 eligible women, 1347 (51.9%) originated from France, 1131 (43.6%) from SSA, and 118 (4.5%) from NFW. SSA and NFW female migrants had a higher aRR for non-AIDS infections, particularly non-bacterial infections (respectively, 2.04 (1.18–3.53) and 7.87 (2.54–24.4), p = 0.0010), than French natives. We observed no other significant differences related to geographic origin as concerns the aRRs for AIDS-related infections or malignancies, or for other non-AIDS events/deaths such as cardiovascular disease, neurological/psychiatric disorders, non-AIDS malignancies and iatrogenic disorders, in either gender. Conclusion: Heterosexual migrants from SSA or NFW living in France have a higher risk of non-AIDS-defining infections than their French native counterparts. Special efforts are needed to prevent infectious diseases among HIV-infected migrants. [ABSTRACT FROM AUTHOR]
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- 2018
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49. Human Immunodeficiency Virus Type 1 Group O Infection in France: Clinical Features and Immunovirological Response to Antiretrovirals.
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Unal, Guillemette, Alessandri-Gradt, Elodie, Leoz, Marie, Pavie, Juliette, Lefèvre, Clément, Panjo, Henri, Charpentier, Charlotte, Descamps, Diane, Barin, Francis, and Simon, François
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DIAGNOSIS of HIV infections ,HIV infection prognosis ,NON-nucleoside reverse transcriptase inhibitors ,RITONAVIR ,HIV infections ,HIV-positive persons ,MEDICAL genetics ,SURVIVAL ,VIRAL load ,HIGHLY active antiretroviral therapy ,KAPLAN-Meier estimator ,CD4 lymphocyte count ,THERAPEUTICS - Abstract
Background. To obtain reliable clinical data of human immunodeficiency virus type 1 group O (HIV-1/O) infection, and immunovirological responses to combination antiretroviral therapy (cART), in a large series of 101 patients. Methods. Piecewise linear models were used to estimate CD4 count before and after cART initiation. Kaplan-Meier survival curves were used to estimate time to reach clinical stage C before antiretroviral therapy (ART) and to analyze time to achieve a plasma viral load (pVL) <40 copies/mL following cART initiation. Immunovirological response was assessed at the most recent visit in patients on active follow-up. Results. Data showed a 16.6% cumulative probability of reaching stage C within 5 years following diagnosis, and a mean CD4 decrease of -30.5 cells/µL/year. cART initiation in ART-naive patients led to a mean CD4 gain of 147 cells/µL after 12 months, and to a median pVL of <40 copies/mL after 3.8 months for 89.3%. Initiation with a nonrecommended nonnucleoside reverse transcriptase inhibitor-based vs a ritonavir-boosted protease inhibitor-based regimen resulted in a much smaller gain of around 100 CD4 cells/µL after 1 year. Patients on follow-up since 2007 had a median CD4 count of 498 cells/µL, and 87% had a pVL <40 copies/mL at the most recent follow-up visit. Conclusions. This work provides unique data on HIV-1/O infection, in favor of a milder natural evolution than HIV-1 group M (HIV-1/M) and of a highly efficient current management, based on HIV-1/M guidelines, despite genetic divergence. Studies of comparable HIV-1/M and HIV-1/O populations are needed to confirm these results. [ABSTRACT FROM AUTHOR]
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- 2018
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50. Evaluating the Impact of Computerized Provider Order Entry on Medical Students Training at Bedside: A Randomized Controlled Trial
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Wack, Maxime, primary, Puymirat, Etienne, additional, Ranque, Brigitte, additional, Georgin-Lavialle, Sophie, additional, Pierre, Isabelle, additional, Tanguy, Aurelia, additional, Ackermann, Felix, additional, Mallet, Celine, additional, Pavie, Juliette, additional, Boultache, Hakima, additional, Durieux, Pierre, additional, and Avillach, Paul, additional
- Published
- 2015
- Full Text
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