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[Purpose/Significance] Through multi-dimensional analysis of archives utilization data of scientific research institutions, we can extract and summarize the overall characteristics and rules of the utilization behavior of archive users in scientific research institutions, which can help to improve the capacity of archives utilization service in a targeted manner. [Method/Process] The archives utilization data of two typical research institutions (the Archives of Chinese Academy of Sciences and the National Natural Science Foundation of China) were analyzed in terms of time, content and purpose. [Result/Conclusion] Some archives utilization demands of scientific research institution are correlated with specific time points. Archive users are more concerned with featured archive resources and thematic archive resources. And there is a correlation between the purpose of archive users' utilization and the time of archives utilization and the subject content of the archives utilized. Scientific research institutions can enhance their archives utilization service capacity by strengthening the construction of featured archive resources, establishing thematic archive databases, carrying out hierarchical storage of digital archive resources, and grasping the timing of archive resources exploitation and utilization.

The ideal and highly anticipated dressing for skin wounds should provide a moist environment, possess antibacterial properties, and ensure sustained drug release. In the present work, a hyaluronic acid‐based hydrogel was formed by cross‐linking crocetin and CaCO3@polyelectrolyte materials (CaCO3@PEM) microspheres with HA hydrogels via hydrogen bond and amido bonding (CaCO3@PEM@Cro@HA hydrogel, CPC@HA hydrogel). Moreover, the CPC@HA hydrogel had the capability of sustained, controlled release of calcium ions and crocetin via pH‐sensitive and accelerated skin wound healing. The experiment results showed that the CPC@HA hydrogel exhibited porous network structures, stable physical properties, and had antibacterial properties and biocompatibility in vitro. In addition, the CPC@HA hydrogel covering on the skin wound could reduce inflammation and promote wound healing. The high expression of angiogenic cytokines (CD31) and epidermal terminal differentiation markers (Loricrin) of wound healing tissue suggested the CPC@HA hydrogel also had the function of promoting the remodeling of regenerated skin. Overall, CPC@HA hydrogel has promising potential for clinical applications in accelerating skin wound repair. [ABSTRACT FROM AUTHOR]

We propose a glucose‐powered Janus nanomotor where two faces are functionalized with glucose oxidase (GOx) and polydopamine‐Fe3+ chelates (PDF), respectively. In the glucose fuel solution, the GOx on the one side of these Janus nanomotors catalytically decomposes glucose fuels into gluconic acid and hydrogen peroxide (H2O2) to drive them at a speed of 2.67 μm/s. The underlying propulsion mechanism is the glucose‐based self‐diffusiophoresis owing to the generated local glucose concentration gradient by the enzymatic reaction. Based on the enhanced diffusion motion, such nanomotors with catalytic activity increase the uptake towards cells and subsequently exhibit excellent capabilities for Fe3+ ions delivery and H2O2 generation for enhancing ferroptosis efficiency for inducing cancer cell death. In particular, the Fe3+ ions are released from nanomotors in a slightly acidic environment, and subsequently generate toxic hydroxyl radicals via Fenton reactions, which accumulation reactive oxygen species (ROS) level (~300 %) and further lipid peroxidation (LPO) strengthened ferroptosis therapy for cancer treatment. The as‐developed glucose‐powered Janus nanomotor with efficient diffusion and Fe ions delivery capabilities show great promise as a potential in biomedical applications. [ABSTRACT FROM AUTHOR]