137 results on '"P Terrosu"'
Search Results
2. Correction to: Surgical treatment of colonic Crohn’s disease: a national snapshot study
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Celentano, Valerio, Pellino, Gianluca, Rottoli, Matteo, Poggioli, Gilberto, Sica, Giuseppe, Giglio, Mariano Cesare, Campanelli, Michela, Coco, Claudio, Rizzo, Gianluca, Sionne, Francesco, Colombo, Francesco, Sampietro, Gianluca, Lamperti, Giulia, Foschi, Diego, Ficari, Ferdinando, Vacca, Ludovica, Cricchio, Marta, Giudici, Francesco, Selvaggi, Lucio, Sciaudone, Guido, Peltrini, Roberto, Manfreda, Andrea, Bucci, Luigi, Galleano, Raffaele, Ghazouani, Omar, Zorcolo, Luigi, Deidda, Simona, Restivo, Angelo, Braini, Andrea, Di Candido, Francesca, Sacchi, Matteo, Carvello, Michele, Martorana, Stefania, Bordignon, Giovanni, Angriman, Imerio, Variola, Angela, Barugola, Giuliano, Di Ruscio, Mirko, Tanzanu, Marta, Geccherle, Andrea, Tropeano, Francesca Paola, Luglio, Gaetano, Sasia, Diego, Migliore, Marco, Giuffrida, Maria Carmela, Marrano, Enrico, Moretto, Gianluigi, Impellizzeri, Harmony, Gallo, Gaetano, Vescio, Giuseppina, Sammarco, Giuseppe, Terrosu, Giovanni, Calini, Giacomo, Bondurri, Andrea, Maffioli, Anna, Zaffaroni, Gloria, Resegotti, Andrea, Mistrangelo, Massimiliano, Allaix, Marco Ettore, Botti, Fiorenzo, Prati, Matteo, Boni, Luigi, Perotti, Serena, Mineccia, Michela, Giuliani, Antonio, Romano, Lucia, Graziano, Giorgio Maria Paolo, Pugliese, Luigi, Pietrabissa, Andrea, Delaini, GianGaetano, Spinelli, Antonino, and Selvaggi, Francesco
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- 2022
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3. Re-thinking of T-tube use in whole liver transplantation: an analysis on the risk of delayed graft function
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Pravisani, Riccardo, Isola, Miriam, Lorenzin, Dario, Cherchi, Vittorio, Boscolo, Erica, Mocchegiani, Federico, Terrosu, Giovanni, and Baccarani, Umberto
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- 2022
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4. Indocyanine green dye clearance test: early graft (dys)-function and long-term mortality after liver transplant. Should we continue to use it? An observational study
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Cherchi, Vittorio, Vetrugno, Luigi, Zanini, Victor, Isler, Thomas, Pravisani, Riccardo, Borghi, Alice, Baccarani, Umberto, Terrosu, Giovanni, Risaliti, Andrea, and Bove, Tiziana
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- 2021
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5. Anastomosis configuration and technique following ileocaecal resection for Crohn’s disease: a multicentre study
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Celentano, Valerio, Pellino, Gianluca, Spinelli, Antonino, Selvaggi, Francesco, Celentano, Valerio, Pellino, Gianluca, Rottoli, Matteo, Poggioli, Gilberto, Sica, Giuseppe, Giglio, Mariano Cesare, Campanelli, Michela, Coco, Claudio, Rizzo, Gianluca, Sionne, Francesco, Colombo, Francesco, Sampietro, Gianluca, Lamperti, Giulia, Foschi, Diego, Ficari, Ferdinando, Vacca, Ludovica, Cricchio, Marta, Giudici, Francesco, Selvaggi, Lucio, Sciaudone, Guido, Peltrini, Roberto, Manfreda, Andrea, Bucci, Luigi, Galleano, Raffaele, Ghazouani, Omar, Zorcolo, Luigi, Deidda, Simona, Restivo, Angelo, Braini, Andrea, Di Candido, Francesca, Sacchi, Matteo, Carvello, Michele, Martorana, Stefania, Bordignon, Giovanni, Angriman, Imerio, Variola, Angela, Di Ruscio, Mirko, Barugola, Giuliano, Geccherle, Andrea, Tropeano, Francesca Paola, Luglio, Gaetano, Tanzanu, Marta, Sasia, Diego, Migliore, Marco, Giuffrida, Maria Carmela, Marrano, Enrico, Moretto, Gianluigi, Impellizzeri, Harmony, Gallo, Gaetano, Vescio, Giuseppina, Sammarco, Giuseppe, Terrosu, Giovanni, Calini, Giacomo, Bondurri, Andrea, Maffioli, Anna, Zaffaroni, Gloria, Resegotti, Andrea, Mistrangelo, Massimiliano, Allaix, Marco Ettore, Botti, Fiorenzo, Prati, Matteo, Boni, Luigi, Perotti, Serena, Mineccia, Michela, Giuliani, Antonio, Romano, Lucia, Graziano, Giorgio Maria Paolo, Pugliese, Luigi, Pietrabissa, Andrea, Delaini, GianGaetano, Spinelli, Antonino, and Selvaggi, Francesco
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- 2021
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6. Integrated multi-omics analyses on patient-derived CRC organoids highlight altered molecular pathways in colorectal cancer progression involving PTEN
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Codrich, Marta, Dalla, Emiliano, Mio, Catia, Antoniali, Giulia, Malfatti, Matilde Clarissa, Marzinotto, Stefania, Pierobon, Mariaelena, Baldelli, Elisa, Di Loreto, Carla, Damante, Giuseppe, Terrosu, Giovanni, Pucillo, Carlo Ennio Michele, and Tell, Gianluca
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- 2021
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7. Acute cholecystitis during COVID-19 pandemic: a multisocietary position statement
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Campanile, Fabio Cesare, Podda, Mauro, Arezzo, Alberto, Botteri, Emanuele, Sartori, Alberto, Guerrieri, Mario, Cassinotti, Elisa, Muttillo, Irnerio, Pisano, Marcello, Brachet Contul, Riccardo, D’Ambrosio, Giancarlo, Cuccurullo, Diego, Bergamini, Carlo, Allaix, Marco Ettore, Caracino, Valerio, Petz, Wanda Luisa, Milone, Marco, Silecchia, Gianfranco, Anania, Gabriele, Agrusa, Antonino, Di Saverio, Salomone, Casarano, Salvatore, Cicala, Caterina, Narilli, Piero, Federici, Sara, Carlini, Massimo, Paganini, Alessandro, Bianchi, Paolo Pietro, Salaj, Adelona, Mazzari, Andrea, Meniconi, Roberto Luca, Puzziello, Alessandro, Terrosu, Giovanni, De Simone, Belinda, Coccolini, Federico, Catena, Fausto, and Agresta, Ferdinando
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- 2020
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8. Impact of surgical complications on the risk of hepatocellular carcinoma recurrence after hepatic resection
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Pravisani, Riccardo, Baccarani, Umberto, Isola, Miriam, Adani, Gianluigi, Lorenzin, Dario, Terrosu, Giovanni, and Risaliti, Andrea
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- 2018
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9. Ferric carboxymaltose for iron deficiency at discharge after acute heart failure
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Stefano Savonitto, D Soon, V Tseluyko, J Heymeriks, L Petrescu, Fabio T. M. Costa, P Garcia Pacho, G Chapidze, Michael Motro, M Diez, A Prado, Piotr Ponikowski, Sanjib Kumar Sharma, DL Serban, A. Salvioni, S del Prado, Giuseppe Boriani, Stephan von Haehling, HG Cestari, PR Nierop, LC Iosipescu, Hans Kragten, Má Hominal, Bridget-Anne Kirwan, Andre Keren, D Horvat, J Thierer, D Sim, Rabih R. Azar, Peter van der Meer, G Stanciulescu, F Cosmi, Sy Loh, Jarosław Drożdż, David Sim, K Paposhvili, M Berli, Alain Cohen-Solal, Stefan D. Anker, Arnaout, ML Parody, GO Zapata, T Ben-Gal, J Schaap, Bas L.J.H. Kietselaer, O Raed, G Kiwan, Marco Metra, Shaul Atar, Udo Michael Göhring, Edoardo Gronda, A Ružić, C Beltrano, Dpw Beelen, Davor Milicic, R Ray, JM Weinstein, FI Ga Bosa Ojeda, Y-K Wong, Dalton Bertolim Précoma, Javed Butler, JR Gonzalez Juanatey, V Chumburidze, Gerasimos Filippatos, V Witzling, Y Malynovsky, I Kraiz, A Samodol, J Trevelyan, L Nigro Maia, M Stanislavchuk, Gilmar Reis, I Khintibidze, D Zdrenghea, Beata Wożakowska-Kapłon, BD Molina, C Abdallah, Ham van Kesteren, Tim Friede, Marcin Gruchała, Majdi Halabi, Ewa A. Jankowska, P Van Bergen, Constantin Militaru, O Koval, DA Darabantiu, A Kormann, J Szachniewicz, Maria Dorobantu, M van de Wetering, R Nijmeijer, H Hamdan, Stefano Ghio, Henry J. Dargie, G Azize, Nicolas Danchin, S Chaaban, S Gerward, P Pimentel Filho, M Uguccioni, K Abdelbaki, N Vita, J.F.K. Saraiva, D Almeida, Michael Shochat, M Ohlsson, R Van de Wal, V Zolotaikina, W Kinany, A Tycińska, A Hershson, T Shaburishvili, Vincent Fabien, FR dos Santos, Alfredo Bardají, Rgej Groutars, M Flugelman, J Bono, M Udovicic, M Artuković, K Šutalo, J Drozdz, TJ Yeo, F Ferre Pacora, Z Lominadze, M Emans, S Pettit, HA Luquez, P Terrosu, Marcus Ohlsson, M Gąsior, S Tušek, Enrico Passamonti, Nyy Al-Windy, P Midi, DA Pascual Figal, P van der Meer, V Zvi, Wilco Tanis, Felipe Martinez, RR Borelli, Diana A. Gorog, O Parhomenko, Klaus H Jensen, M Meijs, J Nessler, M Piepoli, DM Toader, Jose C. Nicolau, A Glenny, José Luis Zamorano, L Tilling, T McDonagh, K Pesek, H Fernandez, Davor Miličić, Domingo A. Pascual-Figal, Theresa McDonagh, G Khabeishvili, Josep Comin-Colet, Israel Gotsman, S Rassi, M Dorobantu, E Straburzyńska-Migaj, L Fattore, L Rudenko, D Crisu, S.S. Kabbani, M Gomez Bueno, Basil S. Lewis, S Goland, Y Arbel, M Bronisz, I Vakaliuk, A Fucili, A Mortara, R Zukermann, N Emukhvari, B Hassouna, K Mizia-Stec, F Turrini, R Szelemej, A Rodica Dan, L Lobo Marquez, Hadi Skouri, A Kabir, Frank Ruschitzka, R García Durán, R Gil, Michael Shechter, P Westendorp, Piergiuseppe Agostoni, A Fernandez, Oscar Pereira Dutra, P Ameri, Wolfram Doehner, JG Smith, Irakli Khintibidze, Luciano Moreira Baracioli, J Šikić, Stuart Pocock, Olivier C. Manintveld, MC Tomescu, M Di Biase, Luiz Carlos Bodanese, E Mirek-Bryniarska, Alexander Parkhomenko, Cardiovascular Centre (CVC), Restoring Organ Function by Means of Regenerative Medicine (REGENERATE), Cardiology, leboeuf, Christophe, Wrocław Medical University, London School of Hygiene and Tropical Medicine (LSHTM), Charité - UniversitätsMedizin = Charité - University Hospital [Berlin], King's College Hospital (KCH), Universitatea din Bucuresti (UB), University of Lódź, Vifor Pharma Ltd [Glattbrugg, Switzerland], National and Kapodistrian University of Athens (NKUA), Hadassah Hebrew University Medical Center [Jerusalem], Tbilisi State University, Maastricht University Medical Centre (MUMC), Maastricht University [Maastricht], Prague University of Economics and Business, Università degli Studi di Brescia = University of Brescia (UniBs), University of Zagreb, Universidade de São Paulo = University of São Paulo (USP), Skane University Hospital [Malmo], Lund University [Lund], National Scientific Center 'M.D. Strazhesko Institute of Cardiology' [Kyiv, Ukraine] (NSC/MDSIC), Universidad de Murcia, University hospital of Zurich [Zurich], National Heart Centre Singapore (NHCS), Saint Joseph Medical Center [Beirut], University Medical Center Groningen [Groningen] (UMCG), Clinical Cardiovascular Research Institute [Haifa, Israel] (2CRI), Bellvitge University Hospital [Barcelona, Spain], University Medical Center Göttingen (UMG), Biomarqueurs CArdioNeuroVASCulaires (BioCANVAS), Université Paris 13 (UP13)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Charité Campus Virchow-Klinikum (CVK), University of Glasgow, Tel Aviv University (TAU), University of Southern Mississippi (USM), Socar Research S.A. [Nyon, Switzerland] (SR), and AFFIRM-AHF investigators: G Azize, A Fernandez, G O Zapata, P Garcia Pacho, A Glenny, F Ferre Pacora, M L Parody, J Bono, C Beltrano, A Hershson, N Vita, H A Luquez, H G Cestari, H Fernandez, A Prado, M Berli, R García Durán, J Thierer, M Diez, L Lobo Marquez, R R Borelli, M Á Hominal, M Metra, P Ameri, P Agostoni, A Salvioni, L Fattore, E Gronda, S Ghio, F Turrini, M Uguccioni, M Di Biase, M Piepoli, S Savonitto, A Mortara, P Terrosu, A Fucili, G Boriani, P Midi, E Passamonti, F Cosmi, P van der Meer, P Van Bergen, M van de Wetering, Nyy Al-Windy, W Tanis, M Meijs, Rgej Groutars, Hks The, B Kietselaer, Ham van Kesteren, Dpw Beelen, J Heymeriks, R Van de Wal, J Schaap, M Emans, P Westendorp, P R Nierop, R Nijmeijer, O C Manintveld, M Dorobantu, D A Darabantiu, D Zdrenghea, D M Toader, L Petrescu, C Militaru, D Crisu, M C Tomescu, G Stanciulescu, A Rodica Dan, L C Iosipescu, D L Serban, J Drozdz, J Szachniewicz, M Bronisz, A Tycińska, B Wozakowska-Kaplon, E Mirek-Bryniarska, M Gruchała, J Nessler, E Straburzyńska-Migaj, K Mizia-Stec, R Szelemej, R Gil, M Gąsior, I Gotsman, M Halabi, M Shochat, M Shechter, V Witzling, R Zukermann, Y Arbel, M Flugelman, T Ben-Gal, V Zvi, W Kinany, J M Weinstein, S Atar, S Goland, D Milicic, D Horvat, S Tušek, M Udovicic, K Šutalo, A Samodol, K Pesek, M Artuković, A Ružić, J Šikić, T McDonagh, J Trevelyan, Y-K Wong, D Gorog, R Ray, S Pettit, S Sharma, A Kabir, H Hamdan, L Tilling, L Baracioli, L Nigro Maia, O Dutra, G Reis, P Pimentel Filho, J F Saraiva, A Kormann, F R Dos Santos, L Bodanese, D Almeida, D Precoma, S Rassi, F Costa, S Kabbani, K Abdelbaki, C Abdallah, M S Arnaout, R Azar, S Chaaban, O Raed, G Kiwan, B Hassouna, A Bardaji, J Zamorano, S Del Prado, J R Gonzalez Juanatey, F I Ga Bosa Ojeda, M Gomez Bueno, B D Molina, D A Pascual Figal, D Sim, T J Yeo, S Y Loh, D Soon, M Ohlsson, J G Smith, S Gerward, I Khintibidze, Z Lominadze, G Chapidze, N Emukhvari, G Khabeishvili, V Chumburidze, K Paposhvili, T Shaburishvili, G Khabeishvili, O Parhomenko, I Kraiz, O Koval, V Zolotaikina, Y Malynovsky, I Vakaliuk, L Rudenko, V Tseluyko, M Stanislavchuk.
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Male ,medicine.medical_specialty ,Anemia ,030204 cardiovascular system & hematology ,Rate ratio ,Placebo ,Ferric Compounds ,Ventricular Function, Left ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,Double-Blind Method ,Randomized controlled trial ,law ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Maltose ,Adverse effect ,TOLVAPTAN ,Aged ,Aged, 80 and over ,Heart Failure ,RISK ,Ejection fraction ,Anemia, Iron-Deficiency ,business.industry ,MORTALITY ,Hazard ratio ,DEATH ,General Medicine ,Middle Aged ,medicine.disease ,Patient Discharge ,[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,3. Good health ,Hospitalization ,Treatment Outcome ,Heart failure ,Administration, Intravenous ,Female ,HOSPITALIZATIONS ,business - Abstract
Background: Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure. Methods: AFFIRM-AHF was a multicentre, double-blind, randomised trial done at 121 sites in Europe, South America, and Singapore. Eligible patients were aged 18 years or older, were hospitalised for acute heart failure with concomitant iron deficiency (defined as ferritin
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- 2020
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10. Applicability of laparoscopic approach to the resection of large adrenal tumours: a retrospective cohort study on 200 patients
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Feo, Carlo V., Portinari, Mattia, Maestroni, Umberto, Del Rio, Paolo, Severi, Silvia, Viani, Lorenzo, Pravisani, Riccardo, Soliani, Giorgio, Zatelli, Maria Chiara, Ambrosio, Maria Rosaria, Tong, Jenny, Terrosu, Giovanni, and Bresadola, Vittorio
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- 2016
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11. Endoscopic failure for foreign body ingestion and food bolus impaction in the upper gastrointestinal tract: an updated analysis in a European tertiary care hospital
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Calini, Giacomo, Ortolan, Naima, Battistella, Claudio, Marino, Marco, Bresadola, Vittorio, and Terrosu, Giovanni
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- 2023
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12. Early Diagnosis and Treatment of Postoperative Endoscopic Recurrence of Crohn’s Disease: Partial Benefit by Infliximab—A Pilot Study
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Sorrentino, Dario, Terrosu, Giovanni, Paviotti, Alberto, Geraci, Marco, Avellini, Claudio, Zoli, Giorgio, Fries, Walter, Danese, Silvio, Occhipinti, Pietro, Croatto, Tiziano, and Zarifi, Dimitra
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- 2012
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13. Anal avulsion caused by abdominal crush injury
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Terrosu, G., Rossetto, A., Kocjancic, E., Rossitti, P., and Bresadola, V.
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- 2011
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14. Prevalence of diabetic and impact on cardiovascular events and mortality in patients with chronic coronary syndromes, across multiple geographical regions and ethnicities
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H Appeltants, C Boesch, I Cromarty, D Carretta, S Romanov, U Windstetter, F Mibach, Jens Refsgaard, S Lebedev, F Proietti, M Y Tamimi, M C Gamboa, M Novikova, E Prada, K H Sim, E Messas, E Zherlitsyna, A Kalampalikis, N Nevolina, N Trocan, J Cohen, G Szto, R Gilabert Gómez, M Omelchenko, A Pinzani, D Goodwin, J Umaran Sánchez, Kim Fox, S H Dong, K Kronberg, E Castillo Lueña, T Ignatieva, S Joubert, C Macchi, S Lee, S Eidelman, F Alizon, S Chandra, M Akbar, D M Colquhoun, G Yanes Bowden, J de Juan Baguda, M Sebastian, C Wernham, K Miedema, R La Greca, C Morton, B S Jheeta, A C Tran, T Q Do, O Rodrigues, J Yan, S H Kim, R Jurgaitienė, Jean-Claude Tardif, R Baleón, D Hay, V Hennebelle, F Fazekas, R Davies, P Gratia, L Sorodoc, S Y Wu, C Martínez Sánchez, L Lopes Antunes, T H T Pham, I Suliman, M J Gómez Martinez, A Pernat, S H Hur, M Alanazy, L Zhabina, M Stanley, J Rogers, Y J Kim, S Geffroy, L K Andersen, S Coman, V Pedrosa del Moral, Y Garaud, J Krupicka, O Dzhkha, C Paul, M Jeżewska, B Mahler Mioto, V Abduvalieva, P Morra, L Kucheryava, C La Rosa, B Chan, M Wrębiak-Trznadel, A Kozlowski, M Sharif, L López Barreiro, V Kolesnikov, M Lawrence, A Tucker, C Okawabata, B La Hay, E Sadauskienė, B K Nguyen, L Bui, A Said, M E Ruíz Esparza, R K Saran, M S C Ho, E Homs Espinach, J R Romo Santana, J Forte De Carvalho, I Pattison, H H Phan, L Baleeva, L Kisiel, A López Granados, C Raters, F Paganelli, R Haberl, A P T Wong, D Xu, R Jagathesan, L Grekhova, H Stursova, Q B Truong, P Raymond, Y Sosnova, N H Khong, J Zarauza Navarro, C Florescu, L Gorshkova, N Saaidin, E Gordillo Higuero, L Davin, I Budanova, C Lavicka, L Gruznykh, P Bogdański, A Dufka, I Arroja, H A R Tahir, G Wilson, G Kolios, S J Yoon, Simon Cattan, K Berdnik, A Serrano, B Sievers, A Rodríguez Almodóvar, L A Holden, F O'Reilly, D Verleyen, H Hafez, K Nehrig, S M Kang, S Berrisch-Rahmel, E Meyer-Michael, P Samama, L Soares, A K Nguyen, F Tuktarova, C Weytjens, E Sandoval Rodriguez, J Cheng, F M Villasenor, João Morais, B Sullivan, R Zimoląg, Albert V. Smith, S F Ding, J C Louchart, G Guardigli, R Furtak, P Azzolini, S Chushak, J L Delgado Prieto, S Kornienko, K K Sia, J H Shin, F Baylac Domengetroy, P Błaszczak, M Saade, N Černič-Šuligoj, K Coetzee, A Kadleckova, V Scollo, O Larina, R Pal, M M Singh, N Nosova, R Burns, B S Yoo, O Gukov, F Massari, V Antia, A Brattström, G Holt, M Scherbak, V Firastrau, Y J Li, E Mikhailova, L Machado Cesar, C García García, J Pjontek, C Everton Biglow, G Pes, C Brown, A Bumbu, S Felis, R Bosch, M Lazaro, Luigi Tavazzi, R Engel, I Romeo Castillejo, Y S Byun, F Matias, I Grushetskaya, C Mestre-Fernandes, T Kheliya, S Schlesingerova, G Theodorakis, I Tsamopoulos, R Pedretti, A Puente Barragán, M P Vo, B Lammens, T Carruthers, J S Bhatt, A Khodanov, N Pasechnaya, I Petrova, G Boutros, I A Khan, E Le Moal, D Garofalo, H R Malaterre, A Bahal, J F Martínez González, H N Dinh, N V Pham, C Barjhoux, I Gilmour, C Soriano Navarro, O D Chioncel, K Tóth, N Borodina, P Khanoyan, B Sevilla Toral, H H Kim, C M A Bui, C Dernedde, N Eliseeva, M Galinier, E Kosachek, M M Doohan, L Potapska, M Tennekoon, R Nourallah, L Perez De Isla, K H Chee, E Panova, D M Walker, G Glanowska, G Hua, A Silvestre, W Wang, Matthew A. Brown, B Luke, G Jarosiński, R Davis, S Cleron, C Liatas, I Orestis, M Dereń, J Sudnik, S X Zhou, J Fuertes Alonso, O Baranova, S Mingalaeva, T N Vo, K A Ngo, J A Rodríguez Fernández, R Ishmael, G Bode, K K Chan, G Al Radaideh, S Ramphall, H D Theron, V Montagud Saavedra, A Yusuf, G F Mazzanti Mignaqui, L Evtukhova, J Lorenc, D Beacock, O B Šlapikienė, F Alitto, J N Poujois, B Berzal Martín, M Felbermayer, V Mallamaci, T Spitsina, R Ramachandran, A Jánosi, V Dženkevičiūtė, S Gillam, V Joulie, G Esna Ashari, R Henry, E Durand, A Alam, V Fourchard, H Dreycopp, R Fressonnet, C Camossa, O Jerzykowska, M Castrucci, G Sinicropi, B K Goyal, V Vasylenko, R Grogono, M Partington, B Vaquette, R Blindt, Mª T Moreno Casquete, V Kukaleva, W Streb, P F Clavette, M Pérez Paredes, V Hadjiivanov, C Bundy, D E Manyari, A Wassef, J Kuchar, W Nisker, P S Bath, S Panpunnung, G H Choo, Datshana P Naidoo, Y Pavlova, R McManus, N Brand, E Davies, L Prunier, A Schenowitz, P Sternthal, T Sinotova, J Martínez Florez, R Sykulski, J Pinar Sopena, M Balbi, Y Pesant, D A Playford, C Villar Mariscal, F Redding Escalante, W Wongcharoen, O Grechishkina, A Girão, M Speth-Nitschke, K A Mahendran, A Bianco, A Vadavi, G Singh, L Petoin Peuch, L Sukhanova, A Y Y Fong, J L Vega Barbado, A Dzien, S Honorat, G Ansalone, G Kamensky, G McLaren, T B Kim, I Bratu, R Fillet, V Rogozhyna, L Nagy, M Malgina, M A Sheikh Abdul Kader, Z C Li, L Rotaru H Rus, D Adamczyk-Kot, J Estrella, S Serrano García, P Farto E Abreu, D Mescharekova, Su Thillai Vallal, P Seal, S Möller, A Cziráki, T T H Ta, S Davies, H Ge, M Arafah, M Ovize, A Olszewski, V Aboyans, C Roche, F Al Tamimi, L Popova, V Kazachkova, R Rennert, J Aubry, G Bourgeois, J Mackrell, F Al Kandari, N Reifart, J Bérubé, W H J Hutse, O Lysunets, I Butkuvienė, J Cotroneo, J Gdalia, J Dalle Mule, R Santos, B Singh, H Mohammed, A Birkenhagen, T Chiscaneanu, H Sullivan, Jacob A. 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Andrews, L L Feng, B Martina-Hooi, S R Shetty, Y Dascotte, E T Ch'ng, P Dematteo, A Woodall, S Gabriilidis, Jean Ferrières, S K Oh, J Lindford, S Blignaut, L Macedo, R Carrillo Cardoso, Y C Lai, C Lang, S R Jayasinghe, B Bastian, V Sanfins, J de Jeús Zuñiga, F X Meriaux, G Sepp, S Molotyagina, S García Ortego, T Perger, Y Lukina, J H Wirtz, A Regulska, P Durand, P Loheac, J Sinnadurai, S Avlonitis, J García-Moll Marimón, J Bradley, K Pareathumby, L Latyntseva, D Stergiou, K Ling, S K Hong, N S Chonkar, C Goldie, C C Koo, A Salustri, Y Peneva, I Rodríguez Briones, P Ferreira, L Franskyavichene, G Bragança, C Rodrigues, S H Lee, L Dang, B J Lubelsky, L Weinrich, E Hoffer, J Tricoire, M Marachli, O Smirnova, C Falces Salvador, A Mobeirek, M Fagan, A Serazhim, M M W Yeung, F Petitjean, I Cullen, J Benacka, Yañez Wonenburger, D Gentille Lorente, J Ferreira Dos Santos, F Bosa Ojeda, N Marchionni, L Brottier, P Keelan, D Kerö, L Moretti, R Seabra Gomes, I Jasinkevica, P Purnode, D Relange, H N Luqman, A Petit, I Hamilton-Craig, E Kochurov, P Berry, P Aguar Carrascosa, M Noble, S Yvorra, N Razzaq, J M Walch, L Lenartowska, R Sethi, W Kim, C Killeen, S Kurochkina, N Capuano, P Sampson, K H Mak, T Bouchaya, J Hellermann, M Geneves, F Ramos Ariznabarreta, J L Mougeolle, J Ferreira, T Roy, J de Andrés Novales, J F Monteiro Ferreira, M S Mayer, N Lopez Cabanillas, P Touzet, K H Ng, F Pelier, T K Huynh, J Schindler, T Krechunova, A Gaglione, Z Fras, P Haralambus, R Pradhan, L P Low, G Odent, M Sidor, R Sopia, D Janody, T K Ong, K Adamaszek, G Vives Boniato, T Maxwell, H Charles, D Gough, O Dibon, A A Abdul Rahim, H B Liew, S Tikhonova, I Bläse, J Chambel De Aguiar, E Santas Olmeda, M Rosseel, R Angela, D Savard, C Cernetti, O Huttin, J Calder, O Kilaberiya, A Elkrail, I I Tulevski, A Ilyukhina, E Chalkiadakis, R Antonicelli, H C Gwon, G Bautista López, G Brown, J Kojelienė, R Zeitouni, J Mimoso, N Better, N H Vu, H Abdel Wahab, B Poprawa, F Weber, A Ghicu, K Rybak, G Fouquet, C Pindado Rodríguez, A Salakhova, L Isaeva, M H Fallacher, J Placke, G McCansh, V D Tran, O Gusev, D Enayat, P Khera, E Brice, G Levesque, A Alvarez Auñon, M A Arnau, M A López Aranda, E Andreicheva, I Kruck, R Grigoriu, I Sainz Hidalgo, M Węglarz, A Ajani, I Khudina, T Makhieva, V D Dang, R Testa, E Cisowska-Drozd, F Giacomazzi, R Cierpka, Nicola Greenlaw, P Wong, L Simões, L Tsaryabina, O Gureeva, R Raffelsberger, H Luquez, A Rainbird, D Evéquoz, M A Balice-Pasquinelli, R Massay, K L Joseph, I H Chae, R Herrmann, I Salecker, A Montero Gaspar, P F Fonseca, A Martin, W Czarnecki, R Motomancea, E Dechoux, M Shamsuzzaman, M Leandri, D Marzal Martín, C Navas Navas, C Beaurain, T Gkinis, K Shetty, P A Jeannerat, D S Wong, A Gonzaga, W Kulig, J F Millet, E Jankauskienė, E Anastasiou, A I Ruhani, N Aksyutina, O Kolesova, K Yared, M Panajatovic, Y L Zhou, S Thurston, T Alekseeva, S Preston, N Mai, M Kuzyakina, D Rechtman, T Boonyasirinant, J Nobre Dos santos, A Ahuad Guerrero, M Al-Shamiri, M Feldner-Busztin, S Godart, S Liandrat, A Narayan, L Burlakova, M J García Martínez, C Militaru, J Chávez Paez, H B Matheson, D Meddah, P Brindle, N Petrova, A Nicolino, D Spensieri, A Giuca, E Molina Laborda, J Moreno Arribas, V Martinho, T Mularek-Kubzdela, S K Chua, G A Dan, N T H Tu, V T Nguyen, M Alcocer Gamba, J Costa, H Milligan, R Badr-Eslam, E Variava, A Merkhi, C Mays, R De Castro Aritmendiz, A K Mohamed Yusof, A Hamer, R McNeilly, S Dedkova, D Rousson, K Chamou, A Mahr, D C Dan, R Till, T L Yang, M Vida Gutiérrez, D Piyayotai, É Bajcsi, D Zaronskienė, I Alexopoulos, Y Huo, H S Zeng, P Rowe, S Fleming, D B Vu, Á Dongó, C Hand, J C S Leong, M Claeys, S Hood, J Bozkova, G Vieyra, G Unger, A Liqui-Lung, D Cremer Luengo, M Castillo Orive, S Muth, M Joseph, P L Torres Díaz, C Zakopoulos, D Cross, F Trujillo Berraquero, F Sattar, H A Boyrazian, T B Le, M Mantcheva, M Constantinescu, P Gosse, U Keil, G F Vaz, M Bdeir, T S Pham, M J García González, J K Ryu, D W Jeon, Zs Malkócs, J Á Perea Egido, R Izquierdo González, V Probst, E Wellenkamp, C Boureux, M Czarnecka, C Vaughan, H Falconer, H Brunner, G Peña Pérez, E Nelböck-Huber, E Blanc, F Thomas-Richard, A L R Ng, M Provvidenza, R Gascueña Rubia, J Freitas, A Dabboura, B Mörz-Proszowski, A Utech, C Alves, C M David, J A Lastra Galán, L Oliveira, T A Nguyen, I Ghaly, A Hofmeister, I Gorodilova, P Szałkowski, M S Hiremath, G Golovina, C Daly, M Tardy, S Kostomarova, J-P Salembier, P Zagožen, D Wang, M Vogel, J Borbola, I Chlewicka, K-H Schmitz, C Pappas, J Victory, M Garandeau, P Wiggers, C Piñero Ramírez, L Tkhorzhevskaya, E Suglobova, V Samakhovets, P Surmont, H A Ramírez Reyes, M Winter, F Prunier, B Cavert, B Salaun, J M Roca Catalán, A Beinhauer, Ian Ford, K Elsby, V Knyazeva, C Tamburino, V Khoury, A Felice Castro Issa, B Marchenko, K König, A Kennedy, J M Alegret Colomer, T Gillet, Clarify Investigators, B Maheu, A Troncoso Gil, N Haldane, B Koujan, T Mouhat, A Waldman, J Robert, J Campbell, A Kokis, M Micheals, P Gori, P Ramoutar, M Al Zaibag, V Ryzhkova, M Kazakovtseva, C Bernardeau, B Ferreiro Rodríguez, Y Voloshko, S Szabo, I Jarvis, Y N Ke, J Donetti, A Serrano-Garcia, R Ketelers, S Grigoryan, V Kulik, P Zündorf, L Kleemann, J McPherson, M Luaces Méndez, F Mouquet, L G Xiong, T H Tran, P Costello, A Potter, M Cinteza, F Colivicchi, E Nowicka, O Greiner, G Reddy, M Martins Oliveira, F Fernandes De Sousa, P Nocon, R Sewell, I Nikodemska, R Tadeu Munhoz, T Gilbert, I Laizane, M Maroun, B Demianiuk, A Bolidai, R Kacorzyk, R Fernández Mouzo, K Karastanev, J Blanco Castiñeiras, P Messali, R Schwarz, M Vardhani, O Gouli, C Thelemann, A Forclaz, G Khaznadar, G Eisele, P Sosner, M L Bourachot, N Pontikakis, S Heinemann-Meerz, E Zatsarina, E Smrckova, P Calmettes, D H Kang, M L Santos Iglesias, S M Marinescu, A Heap, Melnikova, N F Strathmore, S Tolpygina, M Yang, M Naisseh, E George, J Banach, E Delcoulx, E Teijeira Fernández, J Poles, P Saunders, S Haddad, T Q Luu, A Dhesi, O Prikolota, M Baar, P Lafontaine, C O'Dong, I Petropoulos, B-M Altevogt, D Warden, T De Backer, G Miñana Escrivá, T L Mai, U Schlesinger-Irsch, M M Gomaa, E Moksyuta, M Drexler, P Monteiro, P Grooterhorst, J Moolman, P McAlavey, J O'Shea, L P Quinn, F Crespo, K Srinivasa Reddy, T Shokina, Ellen M. Schmidt, M H Jeong, K Denef, A Pleskof, I Takács, Y Tikhonov, O Ushakov, L Stevens, J Ezcurdia Sasieta, L Nkombua, O Henne Otero, J Y Fraboulet, D S Kim, G Hoh, A Tamm, M Sardon, G Chatzioakim, M A Ulecia Martínez, S Reymond, M Myint, G Proença, R Massabie, E Foster, H Dougall, Anjan Kumar Roy, C Franco Aranda, M Getman, E Filippova, C Aguiar, X D Pu, N Voronina, L L Chen, M Szulc, L Bayakhchan, M J Pinto Vaz, C Niederberger, N Vites, I Sen, Paul R. Kalra, J A Castillo Moreno, W K Ng, C Brunschwig, D Morgan, A Concepción Clemente, N Yakimova, J M Guy, A H Jaafar, J Badarienė, N Taylor, L Compson, R Amor, A Maximovitch, J L Bardají Mayor, E Marín Araez, N H Chau, N Srtumilenko, K Kelly, A Papathanasioy, S Erofeev, B Mamez, A Ribeiro, M Micko, N Alvarenga Recalde, K Atueva, Z Sebõk, P Kycina, A K Gupta, A Laucevičius, R Ahuja, A Prokop, P Stadler, S De Ridder, L Zhang, F B Ramadan, L Kapustina, V Fedoskin, A Bateman, C A Nacht, R Musetescu, M Aparici Feal, A Büttl, S Ross, M Rau, P Federico Zaragoza, G Brisson, M Zagreanu, T T H Pham, F Dominé, N Davydova, N Petrochenko, N Paul, P H Truong, S Frickel, W Bryl, G Brouillette, A Stumpp, M Barrera Bustillos, C Ziccarelli, O Zalyzniak, M eatherhead, N Watkins, G Riccioni, l Kudryavtsev, R Carvalho, J P S Sawhney, V González Toda, P Matos Dias, M Giorgadze, I Rodriguez Marrero, W Gritsch, K Lee, G W Kellam, I Parker, V Ecina, Mª I Soto Ruiz, C Delhomme, T Ivaschenko, Y W Cheah, I Grudtsina, R Chehayeb, T Dookie, O Krasnoslobodskaya, P Jarmużek, F Van den Branden, A M F Vandeplas, A Rocha De Almeida, M Espiga De Macedo, E Łotocka, K Nagy, R Paliulionienė, J L Leyva Pons, N Fedorova, Y Yanina, O Stasuk, Z Vlasuk, P Lim, P Egloff, T Berezhna, A Faria, J Cerda Rojas, E Moser, H G Jin, S J Oh, G Arquero García, K H Karner, I Leontaridis, A Banikova, J Fridrich, H Lesseliers, I Pokrovskaya, P Astridge, H Abdul Manap, R Daniel, C A Almeida Fernández, A Nowowiejska-Wiewióra, B Carvalho De Moura, M Malden, H Rosenstein, S Dixon, G Balogh, M Adam-Blanpain, A Sandalian, H Gervas Pavón, G A Antoniadis, N Naberezhnova, A Amlaiky, P Terrosu, K K H Lau, B Chartier, X Su, O Kovyrshyna, G Beale, P Primot, M H Chen, S S Ramesh, R Chyrek, E Gómez Álvarez, J Rodríguez Collado, G Sibilio, R Jeremiasz, R Colin, C Lalla, G M Fullerton, M P Samal, H Thümmel, R P Patel, J Takhar, H M Kwon, T A Cieza Lara, F Magliari, J Morrell, M Rayo Gutiérrez, T L Orenstein-Lyall, H Choi, S Kulinich, A Aftab, A Wallace, B B Abdul Kareem, S Kwok, A Królak, A Grover, Laurent Fauchier, Mª J Pinilla Lozano, G Sengupta, D Paris, M Al Dhanki, J Milewski, F Petersen Aranguren, H Brufau Redondo, H Mayr, A Arias Mendoza, M Ducoudre, A Correia, J S Awtar Singh, P Aylward, E Brscic, J Du Plooy, J L Arenas León, G Silva Alves, L Sreenivasa Murthy, P Dendale, F La Varra, S Minkin, T Eggeling, A Jamiel, G Lebischak, E Andreev, T V A Tuong, V Chaithiraphan, O Duprez, S Higgins, F Chometon, Y Cottin, A Bonny, C Guyetand, J Matos, F Henpin Yue Cesena, L Polyaeva, M Drijfhout, J Toplak, G E Vertes, N F Wang, J Doucet, A K Trivedi, P Turek, G Chouinard, A Al Lawati, W Filip, F Kovar, T J Cha, A Belanger, H L Cong, J F Robert, D López Gómez, J L Sanz Rodríguez, H Simper, P Shetty, A Chukwu, E Bukanina, C Amoros Galito, H MacCowan, T T T Tran, A Singal, K C Vu, O Ismail, A Ardiaca Capell, P Bousquet, F Goss, Z Galeeva, Maxime Guenoun, B Rijavec, Z Lazerevic, A McCracken, A C Motoc, Y Sharapova, S Wright, A J Paule Sánchez, L Mainar Latorre, I Sirazov, X L Yang, S E Paget, G Berkenboom, J Markenvard, I Surovtseva, S K George, Matthias Simon, M L Fuantos Delgado, C Christoforidis, M Lagares Carballo, P Alvarez García, J Könemann, L Crawford, I Gonos, D Saulnier, E Szabó, L Ardouin, J Bhayat, F J Abardía Oliva, X Bernard, O Sirbu, P Boutsikos, N Khmelevskikh, E Tavlueva, P LeBouthillier, I Bourazanis, A Sequeira, M López Martínez, C P Paulus, R K M Bhaskaran, F Pellerin, B Brown, B Saleh, A Lacchè, R Sola Casado, E Kaźmierczak, M Weingrod, and G Vijayaraghavan
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medicine.medical_specialty ,Cardiac & Cardiovascular Systems ,Epidemiology ,LONG-TERM ,medicine.medical_treatment ,Chronic coronary syndromes ,Coronary Artery Disease ,Revascularization ,Ventricular Function, Left ,GLUCOSE ,MELLITUS ,Risk Factors ,Internal medicine ,Diabetes mellitus ,Diabetes Mellitus ,Ethnicity ,Prevalence ,medicine ,Humans ,ARTERY-DISEASE ,Myocardial infarction ,Stroke ,RISK ,OUTCOMES ,Ejection fraction ,Science & Technology ,business.industry ,Proportional hazards model ,CLARIFY Investigators ,Hazard ratio ,Diabetes ,Stroke Volume ,Geographical disparities ,Syndrome ,medicine.disease ,MIDDLE-EAST ,EUROPEAN-SOCIETY ,Treatment Outcome ,MYOCARDIAL-INFARCTION ,Heart failure ,CLARIFY registry ,Cardiovascular System & Cardiology ,HEART-FAILURE ,Cardiology and Cardiovascular Medicine ,business ,Life Sciences & Biomedicine - Abstract
BackgroundIn contrast with the setting of acute myocardial infarction, there are limited data regarding the impact of diabetes mellitus on clinical outcomes in contemporary cohorts of patients with chronic coronary syndromes. We aimed to investigate the prevalence and prognostic impact of diabetes according to geographical regions and ethnicity.Methods and resultsCLARIFY is an observational registry of patients with chronic coronary syndromes, enrolled across 45 countries in Europe, Asia, America, Middle East, Australia, and Africa in 2009–2010, and followed up yearly for 5 years. Chronic coronary syndromes were defined by ≥1 of the following criteria: prior myocardial infarction, evidence of coronary stenosis >50%, proven symptomatic myocardial ischaemia, or prior revascularization procedure.Among 32 694 patients, 9502 (29%) had diabetes, with a regional prevalence ranging from below 20% in Northern Europe to ∼60% in the Gulf countries. In a multivariable-adjusted Cox proportional hazards model, diabetes was associated with increased risks for the primary outcome (cardiovascular death, myocardial infarction, or stroke) with an adjusted hazard ratio of 1.28 (95% confidence interval 1.18, 1.39) and for all secondary outcomes (all-cause and cardiovascular mortality, myocardial infarction, stroke, heart failure, and coronary revascularization). Differences on outcomes according to geography and ethnicity were modest.ConclusionIn patients with chronic coronary syndromes, diabetes is independently associated with mortality and cardiovascular events, including heart failure, which is not accounted by demographics, prior medical history, left ventricular ejection fraction, or use of secondary prevention medication. This is observed across multiple geographic regions and ethnicities, despite marked disparities in the prevalence of diabetes.ClinicalTrials identifierISRCTN43070564
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- 2021
15. Treatment of perforation in the healthy esophagus: analysis of 12 cases
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Bresadola, Vittorio, Terrosu, Giovanni, Favero, Alessandro, Cattin, Federico, Cherchi, Vittorio, Adani, Gian Luigi, Marcellino, Maria Grazia, Bresadola, Fabrizio, and De Anna, Dino
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- 2008
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16. Efficacy and safety of PCSK9-Inhibitors in the real-world: data from a clinical registry
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Guido Parodi, Pier Sergio Saba, E Gazale, A Murgia, Giuseppe D. Sanna, and P Terrosu
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Secondary prevention ,medicine.medical_specialty ,Geographic area ,business.industry ,Lipid-lowering therapy ,medicine ,LDL Cholesterol Lipoproteins ,Clinical registry ,Cardiology and Cardiovascular Medicine ,Intensive care medicine ,PCSK9 Inhibitors ,business ,Real world data ,Alirocumab - Abstract
Background To date, little information is available on the real impact of PCSK9 inhibitors in terms of reducing cholesterolemia, events and the actual tolerability in the so-called “real world”. This lack of information is substantially related to the fact that these drugs have only been marketed recently. In Italy, few centres are licensed to prescribe these drugs. This, on the one hand, limited the number of patients to whom the new therapy was offered but, on the other hand, “concentrated” the observations in a few centres, making it possible to more easily collect the few data currently available. The Cardiology Unit of our university hospital is the only prescribing centre in the North Sardinia and therefore represents the natural collector of all the prescriptions of this drug in this wide geographical area. Purpose The aim of the study was to evaluate the efficacy and tolerability of PCSK9 inhibitors in the current clinical practice. Methods Data were collected reviewing all Alirocumab and Evolocumab prescriptions provided by the Cardiology Unit of our university hospital included in the Italian National Drug Agency (AIFA) registry from February 2017 to October 2019. In order to collect complete clinical information, all patients were interviewed regarding their health status, the on-treatment cholesterol levels and the possible appearance of side effects or cardiovascular events. Results In the reference period, 111 patients (58.9% males, age 63±10 years) received PCSK9-Inhibitors prescription (52.7% Evolocumab, 47.3% Alirocumab), 86.5% as secondary prevention. Statin intolerance was the indication for PCSK9-Inhibitors in the majority (73.3%) of patients. LDL cholesterol at eligibility evaluation was 175±50 mg/dl and reduced to 87±44 mg/dl (p Conclusions Clinical use of PCSK9 inhibitors confirms its efficacy and safety also in the “real world” setting. LDL reduction occurs early during the treatment and shows a significant trend in further reduction during the observation period. More than 90% of subjects tolerate and persist in PCSK9 inhibitors treatment in the long-term follow-up. Figure 1 Funding Acknowledgement Type of funding source: None
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- 2020
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17. Instrumental clinical restaging, pathological evaluation, and tumor regression grading: how to assess the response to neoadjuvant chemoradiotherapy for rectal cancer
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Benzoni, Enrico, Terrosu, Giovanni, Intersimone, Donatella, Milan, Elisa, Chiaulon, Germana, Bresadola, Vittorio, Sacco, Cosimo, Sattin, Elisa, Bresadola, Fabrizio, and Avellini, Claudio
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- 2007
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18. The Role of Gender and Other Factors as Predictors of Not Receiving Reperfusion Therapy and of Outcome in ST-Segment Elevation Myocardial Infarction
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Cohen, Marc, Gensini, Gian Franco, Maritz, Frans, Gurfinkel, Enrique P., Huber, Kurt, Timerman, Ari, Santopinto, Jose, Corsini, Giancarlo, Terrosu, Pierfranco, and Joulain, Florence
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- 2005
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19. The impact of splenic weight on laparoscopic splenectomy for splenomegaly
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Terrosu, G., Baccarani, U., Bresadola, V., Sistu, M.A., Uzzau, A., and Bresadola, F.
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- 2002
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20. Association between heart and dementia… keep an eye on the left atrium
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Terrosu, Pierfranco
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Atrial fibrillation is associated with an increased risk of cognitive impairment and dementia. The mechanisms are not well known, but they are probably multifactorial and involve atrial myopathy, cardio-embolism, cerebral hypoperfusion, and comorbidities (systemic vascular sclerosis, disease of the small cerebral vessels, inflammation, etc.). Atrial fibrillation therapy could have a protective effect on dementia through diversified actions: (i) prevention of left atrial remodelling; (ii) prevention of cardio-embolism and silent (and not) cerebral infarcts; (iii) improvement of cardiac output and cerebral perfusion. Randomized trials will be needed to clarify the links between left atrium and dementia and to identify the most appropriate therapeutic strategies.
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- 2022
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21. Intraoperative cholangiography in laparoscopic cholecystectomy during residency in general surgery
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Bresadola, V., Intini, S., Terrosu, G., Baccarani, U., Marcellino, M. G., Sistu, M., Scanavacca, F., and Bresadola, F.
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- 2001
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22. Diaphragm rupture in a liver transplant patient under chronic immunosuppressive therapy with sirolimus: rare complication after liver transplantation
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Rossetto, Anna, Baccarani, Umberto, Adani, Gian Luigi, Lorenzin, Dario, Bresadola, Vittorio, and Terrosu, Giovanni
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- 2011
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23. Laparoscopic vs open splenectomy in the management of hematologic diseases
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Donini, A., Baccarani, U., Terrosu, G., Corno, V., Ermacora, A., Pasqualucci, A., and Bresadola, F.
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- 1999
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24. PO221% oxygenated hypothermic machine perfusion in kidney transplantation: Any clinical benefit?
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Pravisani, Riccardo, Baccarani, Umberto, Molinari, Elena, Cherchi, Vittorio, Bacchetti, Stefano, Terrosu, Giovanni, Avital, Itzhak, Ekser, Burcin, and Adani, Gian Luigi
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Background: In deceased donor kidney transplantation (KT), the use of hypothermic machine perfusion (HMP) has been acquiring the status of best practice in the pre-transplant management of kidney grafts. Two types of HMP are currently available, oxygenated HMP and non-oxygenated HMP. However, data on the real clinical impact of oxygenation on KT outcome are still heterogeneous.Methods: Retrospective study on a cohort of 103 patients transplanted with a single kidney graft that was managed either with end-ischemic oxygenated (O2group, Waves Machine, n= 51, 49.5%) or non-oxygenated HMP (no-O2group, Life Port Kidney Transporter Machine, n= 52, 50.5%), during the period January 2016–December 2020. Oxygenation was performed at pO221%.Results: The median cold ischemia time was 29 h:40 min [IQR 26 h:55 min–31 h:10 min] and the prevalence of grafts from extended criteria donors (ECD) was 46.7%, with a median kidney donor profile index (KDPI) of 72 [41–94]. The study groups were homogeneous in terms of recipient characteristics, ischemia times and donor characteristics. O2and no-O2groups showed comparable outcomes in terms of delayed graft function (O2vs no-O2, 21.5% vs 25%, p= 0.58), vascular (0.2% vs 0.2%, p> 0.99) and urologic (13.7% vs 11.5%, p= 0.77) complications, and episodes of graft rejection (11.7% vs 7.7%, p= 0.52). At 1 year follow up, even creatinine serum levels were comparable between the groups (1.27 mg/dL [1.09 and 1.67] vs 1.4 mg/dL [1.9–1.78], p= 0.319), with similar post-transplant trend (p= 0.870). No significant benefit was either observed in ECD or KDPI > 60 subgroups, respectively.Conclusions: Oxygenation at pO221% during HMP seems not to significantly enhance the KT outcomes in terms of postoperative complications or graft function.
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- 2022
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25. Laparoscopic splenectomy in the management of hematological diseases: Surgical technique and outcome of 17 patients
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Terrosu, G., Donini, A., Silvestri, F., Petri, R., Anania, G., Barillari, G., Baccarani, U., Risaliti, A., and Bresadola, F.
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- 1996
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26. Graft Loss Due to Percutaneous Sclerotherapy of a Lymphocele Using Acetic Acid After Renal Transplantation
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Adani, Gian Luigi, Baccarani, Umberto, Bresadola, Vittorio, Lorenzin, Dario, Montanaro, Domenico, Risaliti, Andrea, Terrosu, Giovanni, Sponza, Massimo, and Bresadola, Fabrizio
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- 2005
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27. Pravastatin vs Gemfibrozil in the Treatment of Primary Hypercholesterolaemia
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Malacco, E., Magni, Alberto, Scandiani, L., Casini, A., Albano, S., Ansuini, R., Biasion, T., Biffi, E., Bilardo, G., Boccuzzi, G., Breda, E., Buttafarro, A., Chella, P. S., Chieffo, C., Coletta, D., Coli, L., Colombo, L., Compagnoni, A., D’Amico, G., D’Ascia, C., De Gregori, M., De Joannon, U., Distante, R., Donadon, V., Donnini, P., Fallucca, F., Ferrari, L., Fesce, E., Formoso, L., Furlani, M., Galetta, F., Gianni, R., Giustina, G., Irace, L., Lipizer, A., Maggio, F., Magri, F., Mangiameli, S., Marasco, S., Marchetti, M., Marrazza, B., Melandri, F., Mondillo, G., Montagnani, M., Napoli, C., Neri, G. F., Orlandi, M., Pantaleoni, M., Papa, A., Perrella, G., Pileggi, V., Pilleri, G. P., Pittalis, M., Piva, M., Resta, F., Rodari, T., Savastano, A., Savona, M., Sensi, S., Sorrentino, F., Squadrito, S., Stocchiero, C., Stranieri, A., Susco, G., Tani, F., Tassone, F., Taverniti, R., Terrosu, P. F., Tirella, G., and Vicario, A.
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- 1994
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28. Italian registry of laparoscopic surgery of the spleen
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Torelli, P., Cavaliere, D., Ghinolfi, D., Terrosu, G., Baccarani, U., and Silecchia, G. F.
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- 2002
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29. Laparoscopic treatment of symptomatic lymphoceles after kidney transplantation
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Risaliti, A., Corno, V., Donini, A., Cautero, N., Baccarani, U., Pasqualucci, A., Terrosu, G., Cedolini, C., and Bresadola, F.
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- 2000
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30. FISSIT (Fistula Surgery in Italy) study: A retrospective survey on the surgical management of anal fistulas in Italy over the last 15 years.
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Litta, Francesco, Bracchitta, Salvatore, Naldini, Gabriele, Mistrangelo, Massimiliano, Tricomi, Nicola, La Torre, Marco, Altomare, Donato Francesco, Mozzon, Marta, Testa, Alessandro, Zigiotto, Daniele, Sica, Giuseppe, Tutino, Roberta, Lisi, Giorgio, Marino, Fabio, Luglio, Gaetano, Vergari, Roberto, Terrosu, Giovanni, Cantarella, Francesco, Foti, Nicola, and Giuliani, Antonio
- Abstract
Surgical treatment of anal fistulas is still a challenge. The aims of this study were to evaluate the adoption and healing rates for the different surgical techniques used in Italy over the past 15 years. This was a multicenter retrospective observational study of patients affected by simple and complex anal fistulas of cryptoglandular origin who were surgically treated in the period 2003–2017. Surgical techniques were grouped as sphincter-cutting or sphincter-sparing and as technology-assisted or techno-free. All patients included in the study were followed for at least 12 months. A total of 9,536 patients (5,520 simple; 4,016 complex fistulas) entered the study. For simple fistulas, fistulotomy was the most frequently used procedure, although its adoption significantly decreased over the years (P <.0005), with an increase in sphincter-sparing approaches; the overall healing rate in simple fistulas was 81.1%, with a significant difference between sphincter-cutting (91.9%) and sphincter-sparing (65.1%) techniques (P =.001). For complex fistulas, the adoption of sphincter-cutting approaches decreased, while sphincter-sparing techniques were mildly preferred (P <.0005). Moreover, there was a significant trend toward the use of technology-assisted procedures. The overall healing rate for complex fistulas was 69.0%, with a measurable difference between sphincter-cutting (81.1%) and sphincter-sparing (61.4%; P =.001) techniques and between techno-free and technology-assisted techniques (72.5% and 55.0%, respectively; P =.001). Surgical treatment of anal fistulas has changed, with a trend toward the use of sphincter-sparing techniques. The overall cure rate has remained stable, even if the most innovative procedures have achieved a lower success rate. [ABSTRACT FROM AUTHOR]
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- 2021
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31. Diverticulum of the midthoracic esophagus: Pathogenesis and surgical treatment
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Dado, G., Bresadola, V., Terrosu, G., and Bresadola, F.
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- 2002
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32. Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial
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Ponikowski, Piotr, Kirwan, Bridget-Anne, Anker, Stefan D, McDonagh, Theresa, Dorobantu, Maria, Drozdz, Jarosław, Fabien, Vincent, Filippatos, Gerasimos, Göhring, Udo Michael, Keren, Andre, Khintibidze, Irakli, Kragten, Hans, Martinez, Felipe A, Metra, Marco, Milicic, Davor, Nicolau, José C, Ohlsson, Marcus, Parkhomenko, Alexander, Pascual-Figal, Domingo A, Ruschitzka, Frank, Sim, David, Skouri, Hadi, van der Meer, Peter, Lewis, Basil S, Comin-Colet, Josep, von Haehling, Stephan, Cohen-Solal, Alain, Danchin, Nicolas, Doehner, Wolfram, Dargie, Henry J, Motro, Michael, Butler, Javed, Friede, Tim, Jensen, Klaus H, Pocock, Stuart, Jankowska, Ewa A, Azize, G, Fernandez, A, Zapata, GO, Garcia Pacho, P, Glenny, A, Ferre Pacora, F, Parody, ML, Bono, J, Beltrano, C, Hershson, A, Vita, N, Luquez, HA, Cestari, HG, Fernandez, H, Prado, A, Berli, M, García Durán, R, Thierer, J, Diez, M, Lobo Marquez, L, Borelli, RR, Hominal, MÁ, Metra, M, Ameri, P, Agostoni, P, Salvioni, A, Fattore, L, Gronda, E, Ghio, S, Turrini, F, Uguccioni, M, Di Biase, M, Piepoli, M, Savonitto, S, Mortara, A, Terrosu, P, Fucili, A, Boriani, G, Midi, P, Passamonti, E, Cosmi, F, van der Meer, P, Van Bergen, P, van de Wetering, M, Al-Windy, NYY, Tanis, W, Meijs, M, Groutars, RGEJ, The, HKS, Kietselaer, B, van Kesteren, HAM, Beelen, DPW, Heymeriks, J, Van de Wal, R, Schaap, J, Emans, M, Westendorp, P, Nierop, PR, Nijmeijer, R, Manintveld, OC, Dorobantu, M, Darabantiu, DA, Zdrenghea, D, Toader, DM, Petrescu, L, Militaru, C, Crisu, D, Tomescu, MC, Stanciulescu, G, Rodica Dan, A, Iosipescu, LC, Serban, DL, Drozdz, J, Szachniewicz, J, Bronisz, M, Tycińska, A, Wozakowska-Kaplon, B, Mirek-Bryniarska, E, Gruchała, M, Nessler, J, Straburzyńska-Migaj, E, Mizia-Stec, K, Szelemej, R, Gil, R, Gąsior, M, Gotsman, I, Halabi, M, Shochat, M, Shechter, M, Witzling, V, Zukermann, R, Arbel, Y, Flugelman, M, Ben-Gal, T, Zvi, V, Kinany, W, Weinstein, JM, Atar, S, Goland, S, Milicic, D, Horvat, D, Tušek, S, Udovicic, M, Šutalo, K, Samodol, A, Pesek, K, Artuković, M, Ružić, A, Šikić, J, McDonagh, T, Trevelyan, J, Wong, Y-K, Gorog, D, Ray, R, Pettit, S, Sharma, S, Kabir, A, Hamdan, H, Tilling, L, Baracioli, L, Nigro Maia, L, Dutra, O, Reis, G, Pimentel Filho, P, Saraiva, JF, Kormann, A, dos Santos, FR, Bodanese, L, Almeida, D, Precoma, D, Rassi, S, Costa, F, Kabbani, S, Abdelbaki, K, Abdallah, C, Arnaout, MS, Azar, R, Chaaban, S, Raed, O, Kiwan, G, Hassouna, B, Bardaji, A, Zamorano, J, del Prado, S, Gonzalez Juanatey, JR, Ga Bosa Ojeda, FI, Gomez Bueno, M, Molina, BD, Pascual Figal, DA, Sim, D, Yeo, TJ, Loh, SY, Soon, D, Ohlsson, M, Smith, JG, Gerward, S, Khintibidze, I, Lominadze, Z, Chapidze, G, Emukhvari, N, Khabeishvili, G, Chumburidze, V, Paposhvili, K, Shaburishvili, T, Khabeishvili, G, Parhomenko, O, Kraiz, I, Koval, O, Zolotaikina, V, Malynovsky, Y, Vakaliuk, I, Rudenko, L, Tseluyko, V, and Stanislavchuk, M
- Abstract
Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure.
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- 2020
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33. Relapse of chronic obstructive pulmonary disease and myocardial infarction: what is the connection?
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Terrosu, Pierfranco
- Abstract
Albeit largely underappreciated, chronic obstructive pulmonary disease (COPD) constitutes a major risk factor for cardiovascular diseases in general and for coronary disease in particular. The incidence of myocardial infarction, in fact increases rapidly, after relapse of COPD, with a peak event rate during the first week in the worst forms (those requiring hospitalization). Even though the precise mechanism is not completely defined, it is likely derived from two pathogenetic causes: (i) mismatch between myocardial demand and offer of O2(not fully demonstrated and limited to few cases); (ii) acute coronary thrombosis, probably due to a systemic inflammatory reaction, brought upon by multiple interaction between the infective agent and the host immune system.
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- 2020
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34. Complete substitution of the left ureter with vermicular appendix during hemicolectomy for cancer in an adult patient
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Dal Moro, F., Terrosu, G., Lorenzin, D., Cherchi, V., Goffo, F., Lissandrello, G., Ferraioli, G., Zaborra, C., and Risaliti, A.
- Abstract
We demonstrated that a complete left ureteral substitution with appendix is a feasible and safe technique. To our knowledge, this is the first case of a successful complete substitution of the left ureter with vermicular appendix in an adult patient reported in the literature.
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- 2020
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35. Use of digitalis in the treatment of heart failure: data from the Italian Network on Congestive Heart Failure (IN-CHF)
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Camerini, A, Griffo, R, Aspromonte, N, Ingrilli', F, Lucci, D, Naccarella, F, Maggioni, Ap, IN-CHF INVESTIGATORS- Piemonte Borgomanero (M. Zanetta, A. M. Paino), Casale Monferrato (M. Ivaldi, A. Giusti), Uslenghi, Cuneo (E., Milanese, U., Deorsola), A., Greco Lucchina, Orbassano (P., Pozzi, R., Rabajoli), F., Veruno (P. Giannuzzi, E. Bosimini), Valle d’Aosta Aosta (M. De Marchi, G. Begliuomini), Richichi, Lombardia Belgioioso (I., Ferrari, A., Barzizza), F., Bergamo Riabilitazione Cardiologica (A. Gavazzi, F. Dadda), Bergamo U. O. Cardiologia Cardiovascolare (A. Gavazzi, A. Fontana), Brescia (C. Rusconi, P. Faggiano), Cogo, Cassano D’Adda (R., Castiglioni, G., Gibelli), G., Chiari (F. Bortolini, A. L. Turelli), Como (G. Ferrari, R. Jemoli), Pirelli, Cremona (S., Bianchi, C., Emanuelli), C., De Martini), Desio (M., Erba (G. Maggi, D. Agnelli), Ferrara), Esine (E., Rovelli, Garbagnate Milanese (G., Lureti, G., Cazzani), E., Giordano, Gussago (A., Zanelli, E., Domenighini), D., Legnano (S. De Servi, C. Castelli), Mariano Comense (G. Bellati, E. Moroni), Milano Fondazione Don Carlo Gnocchi IRCCS (M. Ferratini, E. Gara), Malliani, Milano Sacco (A., Muzzupappa, S., Turiel, M., Guzzetti, S., Cappiello), E., Milano Niguarda (S. Klugmann, F. Recalcati), Milano Pio Albergo Trivulzio (S. Corallo, D. Valenti), Cobelli), Montescano (F., Monza (A. Grieco, A. Vincenzi), Schweiger, Passirana-Rho (C., Rusconi, F., Palvarini), M., Ferrari, Pavia IIAARR S. Margherita (E., Carbone), M., Tavazzi, Pavia IRCCS Policlinico San Matteo (L., Campana, C., Serio), A., Croce, Saronno (A., Nassiacos, D., Meloni), S., Seriate (P. Giani, T. Nicoli), Sondalo (G. Occhi, P. Bandini), Sondrio (S. Giustiniani, M. Moizi), Tradate Fondazione S. Maugeri (R. Pedretti, M. Paolucci), Onofri, Tradate Ospedale di Circolo Galmarini (M., Amati, L., Ravetta), M., Venco, Varese Medicina Interna Azienda Ospedaliera e Universitaria (A., Bertolini, A., Saggiorato), P., Salerno Uriarte, Varese U. O. Cardiologia Azienda Ospedaliera e Universitaria (J., Morandi, F., Provasoli), S., Vizzolo Predabissi (M. Lombardo, P. Quorso), P. A. Trento Rovereto Cardiologia Ospedale Civile (G. Vergara, A. Ferro), Rovereto Medicina Ospedale Civile (M. Mattarei, C. Pedrolli), Catania, Veneto Belluno (G., Tarantini, L., Russo), P., Castelfranco Veneto (L. Celegon, G. Candelpergher), Conegliano Veneto (P. Delise, C. Marcon), Guarnerio, Feltre (M., De Cian, F., Agnoli), A., Montebelluna (G. Neri, M. G. Stefanini), Iliceto, Padova (S., Boffa, G. M., Tiso), E., Pieve di Cadore (J. Dalle Mule, A. Stefania), San Bonifacio (R. Rossi, E. Carbonieri), Treviso (P. Stritoni, G. Renosto), Fontanelli, Vicenza (A., Ottani, F., Varotto), L., Perini), Villafranca (G., Friuli Venezia Giulia Gorizia (D. Igidbashian, G. Giuliano), Monfalcone (T. Morgera, E. Barducci), San Vito al Tagliamento (M. Carone, G. Pascottini), Fioretti, Udine A. O. S. Maria della Misericordia (P., Albanese, M. C., Fresco), C., Udine Casa di Cura Città di Udine (P. Venturini, F. Picco), Liguria Arenzano (R. Griffo, A. Camerini), Chierchia, Genova Ospedali Civili (S., Mazzantini, S., Torre), F., Spirito, Genova Ospedali Galliera (P., Derchi, G., Delfino), L., Genova-Sestri Ponente (S. Domenicucci, L. Pizzorno), Località S. Caterina-Sarzana (G. Filorizzo, D. Bertoli), Rapallo (G. Gigli, S. Orlandi), Gentile), Sestri Levante (A., Emilia Romagna Bentivoglio (G. Di Pasquale, R. Vandelli), Bologna Cardiologia Tiarini-Corticella (F. Naccarella, M. Gatti), Forlì (F. Rusticali, G. Morgagni), Modena Medicina d’Urgenza Ospedale Civile S. Agostino (S. Zucchelli, M. Pradelli), Modena U. O. Cardiologia Ospedale Civile S. Agostino (G. R. Zennaro, G. Alfano), Modena, Modena Ospedale Policlinico (M. G., Reggianini, L., Coppi), F., Parma (D. Ardissino, W. Serra), Piacenza (A. Capucci, F. Passerini), Riccione (L. Rusconi, P. Del Corso), Piovaccari, Rimini (G., Bologna, F., Caccamo), L., Gambarati), Scandiano (G., Bernardi, Toscana Castelnuovo Garfagnana (D., Mariani, P. R., Volterrani), C., Cosmi), Cortona (F., Empoli (V. Mazzoni, F. Venturi), Firenze Divisione di Cardiologia A. O. Careggi (D. Antoniucci, G. Moschi), Zuppiroli, Firenze U. O. Cardiologia 3 A. O. Careggi (A., Pieri, F., Beligni), C., Firenze U. O. Cardiologia 2 A. O. Careggi (M. Ciaccheri, G. Castelli), Santoro, Firenze Nuovo Ospedale San Giovanni di Dio (G. M., Minneci, C., Sulla), A., Firenze P. O. di Camerata (F. Marchi, G. Zambaldi), Fucecchio (A. Zipoli, A. Geri Brandinelli), Grosseto (S. Severi, G. Miracapillo), Pesola, Lido di Camaiore (A., Comella, A., Magnacca), M., Lucca (E. Nannini, A. Boni), Mantini, Montevarchi (G., Bongini, M., Palmerini), L., Vergoni, Pescia (W., Italiani, G., Di Marco), S., Pisa A. O. Pisana (M. De Tommasi, A. M. Paci), Pontedera (G. Tartarini, B. Reisenhofer), Umbria Città di Castello (M. Cocchieri, D. Severini), Foligno (L. Meniconi, U. Gasperini), Ambrosio, Perugia (G., Alunni, G., Murrone), A., Spoleto (G. Maragoni, G. Bardelli), Mocchegiani, Marche Ancona Centro Cardiologia Ambulatoriale G. M. Lancisi (R., Pasetti, L., Budini), A., Ancona Divisione di Cardiologia G. M. Lancisi (G. Perna, D. Gabrielli), Russo, Ancona Geriatrico Sestilli-INRCA IRCCS (P., Testarmata, P., Antonicelli), R., Camerino (R. Amici, B. Coderoni), Lazio Albano Laziale (G. Ruggeri, P. Midi), Frascati (G. Giorgi, F. Comito), Frosinone (G. Faticanti, F. Qualandri), Grottaferrata (D. Galileo Faroni, C. Romaniello), Roma INRCA (F. Leggio, D. del Sindaco), Majid Tamiz, Roma C. Forlanini (A., Avallone, A., Suglia), F., Roma Cristo Re (V. Baldo, E. Baldo), Roma I U. O. Cardiologia San Camillo (E. Giovannini, G. Pulignano), Roma II Divisione di Cardiologia con UTIC San Camillo (S. F. Vajola, E. Picchio), Tanzi, Roma Serv. Centr. Cardiologia-PS Cardiologico San Camillo (P., Pozzar, F., Terranova), A., Santini, Roma San Filippo Neri (M., Ansalone, G., Magris), B., Boccanelli, Roma San Giovanni (A., Cacciatore, G., Bottero), G., Palamara, Roma Sandro Pertini (A., Valtorta, C., Salustri), A., Roma S. Andrea (M. Volpe, L. De Biase), Gaspardone, Roma S. Eugenio (A., Amaddeo, F., Barbato), G., Ceci, Roma Santo Spirito (V., Aspromonte, N., Chiera), A., Scabbia, Viterbo (E. V., Pontillo, D., Castellani), R., Abruzzo Popoli (C. Frattaroli, A. Mariani), De Simone, Vasto (G., Levantesi, G., Di Marco), G., Molise Larino Medicina Generale-U. O. Geriatria (F. Porfilio, A. Pasquale Potena), Staniscia, Termoli (D., Colonna, N., Montano), A., Mininni, Campania Napoli Divisione di Cardiologia A. O. V. Monaldi (N., Miceli, D., Scherillo), M., Napoli I Divisione Med-Centro Diagnosi e Cura SCC A. O. V. Monaldi (P. Sensale, O. Maiolica), Napoli Medicina Incurabili (M. Visconti, A. Costa), Napoli Cardiologia San Gennaro (P. Capogrosso, A. Somelli), Vergara, Nola U. O. Cardiologia e UTIC P. O. Maria della Pietà (G., Napolitano, F., Provvisiero), P., Oliveto Citra (G. D’Angelo, P. Bottiglieri), Puglia Bari (G. Antonelli, N. Ciriello), Ignone, Brindisi (G., Angelini, E., Andriulo), C., Casarano (G. Pettinati, F. De Santis), Francavilla Fontana (V. Cito, F. Cocco), Galatina (F. Daniele, A. Zecca), Gallipoli (F. Cavalieri, C. Picani), Lecce Vito Fazzi (F. Magliari, A. De Giorgi), Santoro), Mesagne (V., San Pietro Vernotico (S. Pede, A. Renna), Scorrano (E. De Lorenzi, O. De Donno), Baldi, Taranto S. S. Annunziata (N., Polimeni, G., Russo), V. A., Tricase (A. Galati, R. Mangia), Basilicata Policoro (B. D’Alessandro, L. Truncellito), Calabria Belvedere Marittimo (F. P. Cariello, F. Rosselli), Catanzaro U. O. Cardiologia Policlinico (G. Borrello, M. Affinita), Catanzaro U. O. Malattie Cardiovascolari Policlinico (F. Perticone, C. Cloro), Sollazzo, Cetraro (G., Matta, M., Lopresti), Venneri, Cosenza Cardiologia Annunziata (N., Misuraca, G., Caporale), R., Cosenza Medicina Annunziata (A. Noto, P. Chiappetta), Tassone), Reggio Calabria E. Morelli (F., Salituri), Rossano (S., Iannopollo, Siderno (M., Errigo, C., Marando), G., Trebisacce (L. Donnangelo, G. Meringolo), Canonico), Sicilia Avola (G., Carini, Catania Cannizzaro (V., Coco, R., Franco), M., Catania Cardiochirurgia Ferrarotto (M. Abbate, G. Leonardi), Messina Papardo (R. Grassi, G. Di Tano), Consolo), Messina Piemonte (G., Coglitore, Messina (S., Cento, D., De Gregorio), C., Palermo Casa del Sole Lanza di Trabia (V. Sperandeo, M. Mongiovì), Palermo Buccheri La Ferla FBF (A. Castello, A. M. Schillaci), Palermo Civico e Benfratelli (E. D’Antonio, U. Mirto), Di Pasquale), Palermo G. F. Ingrassia (P., Palermo V. Cervello (A. Canonico, M. Floresta), Battaglia, Palermo P. O. Villa Sofia (A., Ingrillì, F., Cirrincione), V., Piazza Armerina M. Chiello (B. Aloisi, A. Cavallaro), Braschi, Trapani (G. B., Ledda, G., Rizzo), C., Sanna, Sardegna Cagliari San Michele Brotzu (A., Porcu, M., Salis), S., Lai, Cagliari SS. Trinità (C., Pili, G., Piras), S., Iglesias (E. Spiga, G. Pes), Nuoro (G. Mureddu, I. Maoddi), and Sassari SS. Annunziata (P. Terrosu, F. Uras).
- Subjects
Adult ,Heart Failure ,Male ,Dose-Response Relationship, Drug ,Digitalis Glycosides ,Middle Aged ,Prognosis ,Risk Assessment ,Severity of Illness Index ,Survival Analysis ,Drug Administration Schedule ,Drug Utilization ,Treatment Outcome ,Italy ,Atrial Fibrillation ,Heart Function Tests ,Multivariate Analysis ,Ambulatory Care ,Confidence Intervals ,Odds Ratio ,Humans ,Female ,Registries ,Aged ,Retrospective Studies - Abstract
Since the large multicenter DIG trial has shown no effects of digitalis on the all-cause mortality of patients with chronic heart failure (HF), the broad prescription of this drug in patients with HF appears to be at the very least, questionable. The aims of this study were: to analyze prescription patterns of digitalis, from 1995 to 2000, in a large group of outpatients with HF; to analyze the independent predictors of digitalis prescription and to evaluate the impact of the results of the DIG trial on the prescription rate of this drug.From 1995 to 2000, 11 070 HF outpatients (mean age 64 +/- 12 years, ejection fraction 35 +/- 12%) were enrolled in a large Italian database.Out of 11 070 patients, 7198 (65%) were treated with digitalis. At multivariate analysis, the following variables were independently associated with digitalis prescription; atrial fibrillation (odds ratio [OR] 3.3, 95% confidence interval [CI] 2.9-3.8), ejection fraction30% (OR 1.7, 95% CI 1.5-1.9), NYHA class III-IV vs II-III (OR 1.3, 95% CI 1.2-1.5), admission for HF during the previous year (OR 1.4, 95% CI 1.2-1.5). After the publication of the DIG trial, there was a significant reduction in the rate of digitalis prescription: the percentage of patients taking digitalis fell from 68% in 1996-1997 to 61% in 1998-1999 (p0.001).Over 60% of Italian outpatients with HF were treated with digitalis; as expected, patients with a low ejection fraction, atrial fibrillation and in a more advanced stage of HF are more likely to receive this drug. Finally, after the publication of the DIG trial, the rate of digitalis prescription significantly decreased.
- Published
- 2004
36. Pheochromocytoma presenting as an acute coronary syndrome complicated by acute heart failure: The challenge of a great mimic.
- Author
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Sanna, Giuseppe Damiano, Talanas, Giuseppe, Fiore, Giuseppina, Canu, Antonella, and Terrosu, Pierfranco
- Abstract
Pheochromocytoma is a rare neuroendocrine tumor with a highly variable clinical presentation. The serious and potentially lethal cardiovascular complications of these tumors are related to the effects of secreted catecholamines. We describe a case of a 50-year-old woman urgently admitted to our hospital because of symptoms and clinical and instrumental findings consistent with an acute coronary syndrome complicated by acute heart failure. Urgent coronary angiography showed normal coronary arteries. During her hospital stay, the recurrence of episodes characterized by a sudden increase in blood pressure, cold sweating, and nausea allowed us to hypothesize a pheochromocytoma. The diagnosis was confirmed by elevated levels of urinary catecholamines and by the finding of a left adrenal mass on magnetic resonance imaging. The patient underwent left adrenalectomy. Therefore, the initial diagnosis was critically reappraised and reviewed as a cardiac manifestation of a pheochromocytoma during catecholaminergic crisis. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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37. Postsplenectomy recurrence of idiopathic thrombocitopenic purpura: role of laparoscopic splenectomy in the treatment of accessory spleen.
- Author
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LEO, C. A., PRAVISANI, R., BIDINOST, S., BACCARANI, U., BRESADOLA, V., RISALITI, A., and TERROSU, G.
- Published
- 2015
38. Coronary stent dislodgment after deployment during bifurcation treatment with the double kissing crush technique: A case report.
- Author
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Talanas, Giuseppe, Lorenzoni, Giovanni, Fiore, Giuseppina, and Terrosu, Pierfranco
- Abstract
A 50-year-old male was admitted to our institution because of an acute pulmonary edema successfully treated with diuretics. His cardiovascular risk factors include smoking habit and type 2 diabetes mellitus. Since the ECG showed a sinus rhythm 78 bpm and negative T waves in DI and aVL and the echocardiogram showed hypokinesia of the apex and of mid-distal anterior wall of the left ventricle with mild to moderate systolic dysfunction, the patient was scheduled for an elective coronary angiography. The coronary angiography revealed a critical stenosis of the medium left anterior descending (LAD) involving the origin of the 2nd diagonal branch (D2) (Medina 1,1,1). During the planned strategy for the bifurcation treatment according to the double kissing crush technique, we observed a dislodgement of the fully deployed stent in D2. We treat this unusual complication with an additional stent and we conclude the PCI with a good angiographic result. We discuss this very unusual complication and we compared it with other similar cases. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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39. Trattamento chirurgico dei sintomi extraesofagei da MRGE. Punti critici nel percorso diagnostico-terapeutico.
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Londero, F., Leo, C. A., Cattin, F., Cherchi, V., Adani, G. L., Terrosu, G., and Bresadola, V.
- Published
- 2011
40. Cause of Death and Predictors of All‐Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation: Data From ROCKET AF
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Pokorney, Sean D., Piccini, Jonathan P., Stevens, Susanna R., Patel, Manesh R., Pieper, Karen S., Halperin, Jonathan L., Breithardt, Günter, Singer, Daniel E., Hankey, Graeme J., Hacke, Werner, Becker, Richard C., Berkowitz, Scott D., Nessel, Christopher C., Mahaffey, Kenneth W., Fox, Keith A. A., Califf, Robert M., Anderson, J., Bedwell, N., Bilsker, M., Bruce, G., Agah, R., DeSantis, M., Eisenberg, S., Flores, A., Herzog, W., Klein, S., Snyder, H., Krueger, S., Almaguer, E., Lavie, E., Lee, C., Mallis, G., Modi, M., Woodworth, G., Niazi, I., Peart, B., Sundaram, S., Snoddy, B., Sotolongo, R., Moloney, J., Vijayaraghavan, K., Whittier, F., Yellen, L., Banerjee, S., Lustgarten, D., Suresh, D., Gelernt, M., Levinson, L., Ghanekar, R., Kneller, G., Hall, C., Fadl, Y., Pirwitz, M., French, W., Mayer, N., Pugeda, J., Steel, K., Mody, F., Malik, A., Chandna, H., Go, A., Emlein, G., Bowden, W., Moscoso, R., Hodson, R., Berk, M., Pan, D., Pappas, J., Orchard, R., Lynchard, G., Vijay, N., Khan, W., El Khadra, M, Antonishen, M., Cucher, F., Staab, M., Zebrack, J., Borromeo, S, Heilman, J., Chaturvedi, S., Makam, S., Turk, S., Hyers, T., Williams, G., Labroo, A., Gill, S., Myears, D., Weinstein, J., Shanes, J., Chandrashekhar, Y., Shah, S., Reiter, W., Logemann, T., Almquist, A., 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Sebba Barroso, Braga, J., Alessi, S., Gomes, M., Silva, R., Teixeira, M., Costa, F., Motta, M., Sobral Filho, D., Reis, G., Garbelini, B, Zimmermann, S., Pereira Barretto, A., Dohmann, H., Barreto Filho, J., Ghorayeb, N., Borelli, F., Rossi dos Santos, F., Lopes Prudente, M., Vejar, M., Lanas, F., Del Pino, R., Potthoff, S., Charme, G., Aguirre, A., Saldana, A., Garces, E., Bunster, L., Figueroa, H., Olivares, C., Raffo, C., Vergara, E., Sepulveda, P., Jano, G., Morales Alvarado, J., Suarez, R., Urina, M., Perez, G., Quintero, A., Pava, L., Botero Lopez, R., Luengas, C., Hernandez, E., Sanchez, D., Poveda, C., Coronel, J., Beltran, R., Jaramillo, C., Pardo, J., Ponte Negretti, C., Isea, J., Vergara, G., Morr, I., Sim, K., Wan Ahmad, W., Yusof, Z., Rosman, A., Basri, H, Thompson, P., Jeffery, I., Purnell, P., Roberts‐Thomson, P., Heddle, W., Waites, J., Walters, D., Amerena, J., Challa, P., Karrasch, J., Lowy, A., Fitzpatrick, D., Parsons, M., Phan, T., Bladin, C., Donnan, G., Aroney, G., Gerraty, R., Anderson, C., Blombery, P., Martin, P., Tissa Wijeratne, K., Cross, D., Crimmins, D., Packham, D., Jackson, D., Chua, W., Merino, R., Magno, M., Tirador, L., Batalla, E., Manalo, C., Uy, N., Ebo, G., Reyes, E., Bernan, A., Richards, M., Hart, H., Mann, S., Fisher, R., Stewart, R., Wilkins, G., Barber, A., Tan, R., Ong, H., Singh, R., Sukonthasarn, A., Tanomsup, S., Krittayaphong, R., Piamsomboon, C., Piyayotai, D., Sunsaneewitayakul, B., Baek, S., Seo, H., Rim, S., Kim, C., Kim, K., Ryu, K., Jo, S., Tahk, S., Lee, H., Kim, Y., Shin, D., Choi, Y., Chung, N., Namgung, J., Hong, T., Shin, W., Jin, S., Yan, X., Fu, G., Lu, G., Yang, K., Xu, D., Chen, J., Liu, J., Wu, S., Song, J., Liao, Y., Xu, B., Li, Z., Ma, S., Yin, Y., Zhao, Y., Hu, D., Ma, C., Ma, J., Sun, J., Li, H., Hong, X., Yu, B., Lu, Q., Yang, J., Wu, Z., Li, Y., Huang, Y., Wang, Y., Liu, M., Cheng, Y., Yang, T., Chen, K., Wang, H., Yuan, Z., Wang, J., Zeng, Z., Chen, Y., Yavuzgil, O., Kozan, O., Etemoglu, M., Diker, E., Belgi, A., Ceyhan, C., Cin, V., Yilmaz, O., Ata, N., Altunkeser, B., Agacdiken Agir, A., Karadede, A., Topsakal, R., Gulati, R., Madhavan, A., Jain, S., Oomman, A., Janorkar, S., Kumar, P., Madhukar Naik, A., Thacker, H., Rajasekhar, V., Reddy, R., Keshavamurthy, C., Jain, P., Gowdappa, B., Gadkari, M., Abhyankar, A., Ramesh Babu, B., Vydianathan, P., Sinha, S., Garg, N., Rao, S., Gautam, P., Chockalingam, K., Kumbla, M., Panwar, R., Banker, D., Kaste, M., Jäkälä, P., Roine, R., Mihov, A., Raev, D., Yordanova, V., Dimitrova, S., Benov, H., Tsanova, V., Kyolean, M., Marchev, S., Stoikov, A., Zdravkov, N., Ramshev, K., Krastev, A., Stamenova, P., Angelova, I., Pencheva, G., Grigorova, V., Petrauskiene, B., Skripkauskiene, I., Raugaliene, R., Norkiene, S., Mazutavicius, R., Kavoliuniene, A., Aidietiene, S., Aganauskiene, J., Dailydkiene, A., Marcinkeviciene, J., Grigoniene, L., Anusauskiene, J., Kavaliauskiene, R., Lizogub, V., Rudenko, L., Tseluyko, V., Voronkov, L., Sychov, O., Svyshchenko, Y., Sirenko, Y., Serkova, V., Seredyuk, N., Pertseva, T., Netyazhenko, V., Lishnevska, V., Kupchynska, O., Koval, O., Koshukova, G., Karpenko, O., Grishyna, O., Faynyk, A., Dzyak, G., Dyadyk, O., Yena, L., Volkov, V., Rudyk, I., Kopytsya, M., Kononenko, L., Amosova, K., Zhurba, S., Kazimirko, V., Iuzkiv, I., Shershnyova, O., Khomazyuk, T., Batushkin, V., Vykhovanyuk, I., Popik, G., Skrebkov, V., Skurtov, A., Mishchenko, T., Lytvynenko, N., Sokolova, L., Vatutin, M., Shved, M., Rebrov, B., Kadina, L., Vajda, M., Ursol, G., Zheleznyy, V., Vysochanska, T., Gozhenko, A., Fan, K., Ho, D., Tse, H., Yu, C., Wong, L., Yeh, H., Pai, P., Hsieh, I., Huang, C., Hsieh, Y., Yin, W., Tsai, L., Huang, T., Chen, C., Chiang, F., Ueng, K., Charng, M., Marmor, A., Katz, A., Butnaru, A., Lewis, B., Eldar, M., Rosenhack, S., Elias, N., Koifman, B., Shochat, M., Swissa, M., Zimlichman, R., Bental, T., Weiss, A., Ganam, R., Elias, M., Nseir, W., Oliven, A., Brenner, B., and Dayan, M.
- Subjects
atrial fibrillation ,mortality ,rivaroxaban ,stroke ,warfarin ,Atrial Fibrillation ,Sudden Cardiac Death ,Heart Failure ,Ischemic Stroke ,Intracranial Hemorrhage - Abstract
Background: Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all‐cause mortality may guide interventions. Methods and Results: In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose‐adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all‐cause mortality in the 14 171 participants in the intention‐to‐treat population. The median age was 73 years, and the mean CHADS 2 score was 3.5. Over 1.9 years of median follow‐up, 1214 (8.6%) patients died. Kaplan–Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all‐cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33–1.70, P<0.0001) and age ≥75 years (hazard ratio 1.69, 95% CI 1.51–1.90, P<0.0001) were associated with higher all‐cause mortality. Multiple additional characteristics were independently associated with higher mortality, with decreasing creatinine clearance, chronic obstructive pulmonary disease, male sex, peripheral vascular disease, and diabetes being among the most strongly associated (model C‐index 0.677). Conclusions: In a large population of patients anticoagulated for nonvalvular atrial fibrillation, ≈7 in 10 deaths were cardiovascular, whereas <1 in 10 deaths were caused by nonhemorrhagic stroke or systemic embolism. Optimal prevention and treatment of heart failure, renal impairment, chronic obstructive pulmonary disease, and diabetes may improve survival. Clinical Trial Registration URL: https://www.clinicaltrials.gov/. Unique identifier: NCT00403767.
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- 2016
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41. Myocardial Infarction and Rupture After Bronchial Artery Embolization.
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Massi, Francesco, Muretti, Mirko, Coradduzza, Enrico, Poddighe, Carlo, Terrosu, Pierfranco, and Portoghese, Michele
- Abstract
Bronchial artery embolization is a well-known treatment for hemoptysis. Adverse events of this procedure include multiple systemic embolism and infarction. Myocardial infarction has been recently reported during bronchial artery embolization, owing to the presence of a coronary-to-bronchial artery fistula. We report the management of an ischemic left ventricular free wall rupture caused by bronchial artery embolization in a patient with massive hemoptysis, bronchiectasis, and undetected coronary-to-bronchial artery anomalous connection. [ABSTRACT FROM AUTHOR]
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- 2015
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42. Simultaneous analysis of kynurenine and tryptophan in human plasma by capillary electrophoresis with UVdetection
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Zinellu, Angelo, Sotgia, Salvatore, Deiana, Luca, Talanas, Giuseppe, Terrosu, PierFranco, and Carru, Ciriaco
- Abstract
Plasma kynurenine (Kyn)/tryptophan ratio has been proposed as a useful marker for the monitoring activation of the cellular immune system. Here, we describe an easy capillary electrophoresis method with UVdetection for the separation and detection of Kyn and tryptophan in human plasma using methltryptophan as internal standard. The plasma samples were simply treated with acentonitrile for the elimination of proteins, the supernatant was evaporated, and the dried sample was resuspended with water and directly injected on the capillary without sample derivatization procedures. The use of a run buffer composed by 100 mmol/L Bis‐Tris propane at pH2.15 allowed to baseline resolve the analytes within 9 min. Precision tests indicated a good repeatability of our method both for times (CV< 0.53%) and areas (CV< 2.8%). Moreover, a good reproducibility of intra‐assay and interassay tests was obtained (CV < 3.9% and CV < 7.6%, respectively). The obtained limit of detections for Kyn and tryptophane, evaluated at 226 nm, were 0.15 and 0.40 μmol/L, respectively. The method suitability was tested by measuring analyte levels both in healthy volunteers, acute myocardial infarction and chronic kidney disease patients.
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- 2012
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43. Acute Severe Colitis: Infliximab and/or Cyclosporine?
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Fabro, Mauro, Szabo, Hajnalka, Terrosu, Giovanni, Avellini, Claudio, Tabuso, Maria, Fiorino, Gionata, and Sorrentino, Dario
- Abstract
Acute severe ulcerative colitis is a serious condition that requires early hospitalization, with intensive monitoring and treatment. Despite the recent progress in the medical approach of Inflammatory Bowel Diseases acute severe ulcerative colitis remains a clinical challenge, with a mortality rate of nearly 1. As of today, I.V. corticosteroids remain the 1st-line therapy for this complication. For non-responders (up to one-third of patients) possible options are surgery - whose timing is a critical point in the overall management of the disease - or rescue therapy with 2nd- line agents such as Cyclosporine and Infliximab. Here we will review the published studies dealing with the use of these medications in acute severe ulcerative colitis.
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- 2011
44. Laparoscopic Reconstruction After Esophageal Resection for Perforation
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Bresadola, Vittorio, Terrosu, Giovanni, Benzoni, Enrico, Cherchi, Vittorio, Adani, Gian Luigi, Favero, Alessandro, and De Anna, Dino
- Abstract
The authors present 2 cases of esophageal perforation treated using a new 2-step approach, consisting of esophageal resection and delayed reconstruction of the digestive tract after laparoscopic preparation and transposition of the stomach. The method is characterized by the minimally invasive insertion of a gastric tube through the precardial esophageal stump for postoperative enteral nutrition, and by the use of a laparoscopic method in the reconstruction step for gastrolysis and transposition of the stomach. The benefits lie in the opportunity for enteral feeding preparatory to the reconstruction, with no need for any gastrostomy or jejunostomy, and with fewer complications and a better recovery after reconstruction surgery thanks to the use of a laparoscopic method instead of a laparotomy.
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- 2008
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45. Minimally Invasive Esophagectomy
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Benzoni, Enrico, Bresadola, Vittorio, Terrosu, Giovanni, Uzzau, Alessandro, Cedolini, Carla, Intini, Sergio, Noce, Luigi, and Bresadola, Fabrizio
- Abstract
The development of minimally invasive surgery gave birth to an interest in a mini-invasive approach to esophageal cancer; however, it is still considered to be one of the most complex gastrointestinal surgical operations, and many questions still remain unanswered, regarding the oncologic results of a mini-invasive approach in long-term follow-ups. Here, the authors report on the short-term and long-term results of a series of laparoscopic esophagectomies.
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- 2008
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46. Laparoscopic Versus Open Gastroplasty in Esophagectomy for Esophageal Cancer A Comparative Study
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Bresadola, Vittorio, Terrosu, Giovanni, Cojutti, Alessandro, Benzoni, Enrico, Baracchini, Elena, and Bresadola, Fabrizio
- Abstract
How best to approach esophagectomy is a controversial issue. In the last decade, the opportunity to use minimally invasive surgical methods for esophagectomy has been documented, but their real advantages over conventional surgery have yet to be clearly established. The aim of this study was to compare a series of patients who underwent laparoscopic esophagectomy with those who underwent open surgery to ascertain the feasibility, safety, and clinical advantages of the former surgical techniques. Between January 2002 and May 2004, 14 patients with cancer of the esophagus underwent laparoscopic esophagectomy and another 14 had conventional open esophagectomy. Their demographic features, and intraoperative and postoperative data were compared. The 2 groups were comparable in terms of age, American Society of Anesthesiologists score, and site of the neoplasm. The operating times were the same for transhiatal laparoscopic esophagectomy and conventional surgery, although using the thoraco-laparoscopic access took longer than the thoraco-laparotomic procedure (P<0.05). The hospital stay was shorter after laparoscopy (P<0.05). No differences emerged in terms of morbidity, mortality, number of transfusions, and time in the intensive care. The numbers of lymph nodes removed were comparable. In conclusion, it is feasible and safe to use a laparoscopic approach instead of open surgery for esophagectomy, but the former does not offer very significant clinical advantages in the postoperative stage. A shorter hospital stay seems to be the most significant finding. The minimally invasive procedure would seem to assure oncological radicality because it enables lymphadenectomy to be as thorough as in the conventional surgical approach.
- Published
- 2006
47. The Predictive Value of Clinical Evaluation of Response to Neoadjuvant Chemoradiation Therapy for Rectal Cancer
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Benzoni, Enrico, Cerato, Franz, Cojutti, Alessandro, Milan, Elisa, Pontello, Daniele, Chiaulon, Germana, Sacco, Cosimo, Bresadola, Vittorio, and Terrosu, Giovanni
- Abstract
Introduction Multimodality therapy has become the standard treatment for patients with locally advanced (T3 and T4) rectal carcinoma. Accurate preoperative staging of the patients with rectal cancer has increased in importance because the selection of patients with transmural rectal cancer (T3 or T4) or node-positive disease leads to a previous nonsurgical neoadjuvant treatment. The purpose of this study was to evaluate the predictive value of the clinical response to neoadjuvant therapy on the basis of pathological results obtained on rectal cancer patients treated by chemoradiotherapy and surgery.Methods From 1994 to 2003, 58 patients with a primary diagnosis of rectal cancer were studied at our department and enrolled in a neoadjuvant protocol of chemoradiotherapy followed by surgery. All patients were treated by 30 days of chemoradiotherapy. At the end of the chemoradiotherapy, each patient underwent clinical examination, including digital rectal examination, proctoscopy and abdominal-pelvic computerized tomography to define the clinical response to the chemoradiotherapy. Surgical resection was performed in all patients three weeks after the end of chemoradiotherapy, and histological analysis was performed on all resected specimens.Results The clinical complete response rate corresponded to the pathological complete response rate, whereas the clinical evaluation overestimated partial response and stable disease. The pathologic examination revealed that 3.5% of clinical partial responses and 3.4% of clinical stable disease were really pathological progressive disease. Clinical partial response and clinical stable disease positive predictive values were 92.8% and 90.9%, respectively, whereas the clinical progressive disease negative predictive value was 20%. Then, 6.9% of patients believed to have responded to the therapy, or not to have responded or worsened, actually had worsened by the end of the chemoradiotherapy.Conclusions Positive and negative predictive values, in particular for partial response and stable disease, of clinical evaluation of the response to chemoradiotherapy were not high enough to consider clinical evaluation accurate enough to make treatment decisions.
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- 2005
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48. Angiographic features of the coronary arteries during intracoronary thrombolysis
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V Franceschino, Contini Gm, G V Ibba, and P Terrosu
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medicine.medical_specialty ,medicine.medical_treatment ,Myocardial Infarction ,Lumen (anatomy) ,Coronary Disease ,Coronary Angiography ,Coronary thrombosis ,Internal medicine ,Occlusion ,medicine ,Humans ,Myocardial infarction ,Urokinase ,business.industry ,Fibrinolysis ,Thrombolysis ,medicine.disease ,Urokinase-Type Plasminogen Activator ,Coronary arteries ,medicine.anatomical_structure ,Coronary occlusion ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,Research Article ,medicine.drug - Abstract
The angiographic appearance of the coronary arteries during successful thrombolysis with urokinase was determined in 35 patients with acute myocardial infarction. The lysing process passed through several phases: (a) total coronary occlusion with a convex or irregular distal margin (phase 0); (b) increasing patency of the lumen (phase 1); (c) re-establishment of flow but with intraluminal filling defects and delayed distal flow possibly due to microemboli (phase 2); (d) partial or complete disappearance of the filling defects (phase 3); and (e) further widening of the lumen which eventually attains a smooth regular outline (phase 4). The angiographic features which indicate the presence of coronary thrombosis are occlusion with an irregular or scalloped margin, staining with contrast medium, and progressive patency of the occluded vessel showing intraluminal filling defects.
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- 1984
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49. Distant Metastases from Cervical Esophagus Cancer
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Bresadola, Fabrizio, Terrosu, Giovanni, Uzzau, Alessandro, and Bresadola, Vittorio
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AbstractCancer of the cervical esophagus has a poor prognosis in relation to stage. Correct staging is thus essential in order to establish the prognosis and the treatment program. Distant metastases can involve the lymph nodes (mediastinal and celiac lymph nodes) or they can be extranodal visceral types. Correct lymph node staging can be performed with esophageal endoscopic ultrasonography, computed tomography (CT) scan and, currently, with positron emission tomography (PET) and minimally invasive surgery. For hematogenous metastases, CT scan and PET are mainly used, as well as minimally invasive surgery, with the eventual aid of intraoperative ultrasonography.Copyright © 2001 S. Karger AG, Basel
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- 2001
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50. Spontaneous retropharyngeal and mediastinal emphysema: case report.
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Terrosu, G., Rossetto, A., Bresadola, V., and Robiony, M.
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PNEUMOMEDIASTINUM ,HOSPITAL emergency services ,NECK pain treatment ,TOMOGRAPHY ,ANTIBIOTICS ,FIBER optics ,LARYNGOSCOPY ,ALIMENTARY canal ,ESOPHAGUS ,THERAPEUTICS - Abstract
Abstract: We report the case of an uncommon pathological condition affecting a previously healthy 14-year-old boy, who came to the Emergency Room because of sudden, acute lateral-cervical neck pain not related to any other symptom, disease, traumatic event or dangerous behaviour. The diagnosis of spontaneous retropharyngeal and upper mediastinal emphysema was made by means of neck X-ray and neck and thorax CT scan, while the X-ray of the upper digestive tract and the fiberoptic laryngoscopy did not detect any oesophageal fistula or lesions of the pharynx and larynx. Antibiotics and only fluids intake in order to avoid more dangerous complications was the unique successful treatment; in 3 days time the boy was completely pain-free and back to normal activities. [Copyright &y& Elsevier]
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- 2010
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