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Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial

Authors :
Ponikowski, Piotr
Kirwan, Bridget-Anne
Anker, Stefan D
McDonagh, Theresa
Dorobantu, Maria
Drozdz, Jarosław
Fabien, Vincent
Filippatos, Gerasimos
Göhring, Udo Michael
Keren, Andre
Khintibidze, Irakli
Kragten, Hans
Martinez, Felipe A
Metra, Marco
Milicic, Davor
Nicolau, José C
Ohlsson, Marcus
Parkhomenko, Alexander
Pascual-Figal, Domingo A
Ruschitzka, Frank
Sim, David
Skouri, Hadi
van der Meer, Peter
Lewis, Basil S
Comin-Colet, Josep
von Haehling, Stephan
Cohen-Solal, Alain
Danchin, Nicolas
Doehner, Wolfram
Dargie, Henry J
Motro, Michael
Butler, Javed
Friede, Tim
Jensen, Klaus H
Pocock, Stuart
Jankowska, Ewa A
Azize, G
Fernandez, A
Zapata, GO
Garcia Pacho, P
Glenny, A
Ferre Pacora, F
Parody, ML
Bono, J
Beltrano, C
Hershson, A
Vita, N
Luquez, HA
Cestari, HG
Fernandez, H
Prado, A
Berli, M
García Durán, R
Thierer, J
Diez, M
Lobo Marquez, L
Borelli, RR
Hominal, MÁ
Metra, M
Ameri, P
Agostoni, P
Salvioni, A
Fattore, L
Gronda, E
Ghio, S
Turrini, F
Uguccioni, M
Di Biase, M
Piepoli, M
Savonitto, S
Mortara, A
Terrosu, P
Fucili, A
Boriani, G
Midi, P
Passamonti, E
Cosmi, F
van der Meer, P
Van Bergen, P
van de Wetering, M
Al-Windy, NYY
Tanis, W
Meijs, M
Groutars, RGEJ
The, HKS
Kietselaer, B
van Kesteren, HAM
Beelen, DPW
Heymeriks, J
Van de Wal, R
Schaap, J
Emans, M
Westendorp, P
Nierop, PR
Nijmeijer, R
Manintveld, OC
Dorobantu, M
Darabantiu, DA
Zdrenghea, D
Toader, DM
Petrescu, L
Militaru, C
Crisu, D
Tomescu, MC
Stanciulescu, G
Rodica Dan, A
Iosipescu, LC
Serban, DL
Drozdz, J
Szachniewicz, J
Bronisz, M
Tycińska, A
Wozakowska-Kaplon, B
Mirek-Bryniarska, E
Gruchała, M
Nessler, J
Straburzyńska-Migaj, E
Mizia-Stec, K
Szelemej, R
Gil, R
Gąsior, M
Gotsman, I
Halabi, M
Shochat, M
Shechter, M
Witzling, V
Zukermann, R
Arbel, Y
Flugelman, M
Ben-Gal, T
Zvi, V
Kinany, W
Weinstein, JM
Atar, S
Goland, S
Milicic, D
Horvat, D
Tušek, S
Udovicic, M
Šutalo, K
Samodol, A
Pesek, K
Artuković, M
Ružić, A
Šikić, J
McDonagh, T
Trevelyan, J
Wong, Y-K
Gorog, D
Ray, R
Pettit, S
Sharma, S
Kabir, A
Hamdan, H
Tilling, L
Baracioli, L
Nigro Maia, L
Dutra, O
Reis, G
Pimentel Filho, P
Saraiva, JF
Kormann, A
dos Santos, FR
Bodanese, L
Almeida, D
Precoma, D
Rassi, S
Costa, F
Kabbani, S
Abdelbaki, K
Abdallah, C
Arnaout, MS
Azar, R
Chaaban, S
Raed, O
Kiwan, G
Hassouna, B
Bardaji, A
Zamorano, J
del Prado, S
Gonzalez Juanatey, JR
Ga Bosa Ojeda, FI
Gomez Bueno, M
Molina, BD
Pascual Figal, DA
Sim, D
Yeo, TJ
Loh, SY
Soon, D
Ohlsson, M
Smith, JG
Gerward, S
Khintibidze, I
Lominadze, Z
Chapidze, G
Emukhvari, N
Khabeishvili, G
Chumburidze, V
Paposhvili, K
Shaburishvili, T
Khabeishvili, G
Parhomenko, O
Kraiz, I
Koval, O
Zolotaikina, V
Malynovsky, Y
Vakaliuk, I
Rudenko, L
Tseluyko, V
Stanislavchuk, M
Source :
The Lancet; December 2020, Vol. 396 Issue: 10266 p1895-1904, 10p
Publication Year :
2020

Abstract

Intravenous ferric carboxymaltose has been shown to improve symptoms and quality of life in patients with chronic heart failure and iron deficiency. We aimed to evaluate the effect of ferric carboxymaltose, compared with placebo, on outcomes in patients who were stabilised after an episode of acute heart failure.

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
396
Issue :
10266
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs54826388
Full Text :
https://doi.org/10.1016/S0140-6736(20)32339-4