1. [Alder's anomaly in mucopolysaccharidosis type VI. Cytological, cytochemical and ultrastructural study].
- Author
-
Audroin C, Lejeune F, Gaudelus J, Furioli J, Lortholary P, Joubert J, and Oury-Diot M
- Subjects
- Bone Marrow pathology, Child, Cytoplasmic Granules pathology, Granulocytes pathology, Hematologic Diseases pathology, Histocytochemistry, Humans, Leukocytes enzymology, Lymphocytes pathology, Macrophages pathology, Microscopy, Electron, Mucopolysaccharidosis VI pathology, Neutrophils pathology, Hematologic Diseases complications, Leukocytes pathology, Mucopolysaccharidoses complications, Mucopolysaccharidosis VI complications
- Abstract
A cytological study of the blood and bone marrow of a child with mucopolysaccharidosis with Alder's anomaly was analysed at the optical and ultrastructural level. Morphological abnormalities of the blood and bone marrow leucocytes are defined; cytochemical and cytoenzymological abnormalities are indicated, allowing a differential diagnosis with "toxic granulations". The ultrastructural patterns of the storage cells are described compared to descriptions in the literature and the question of their mastocytic or macrophagic filiation is discussed.
- Published
- 1985