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1. Finite difference calculus in the continuum

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Lytvynov, Eugene, and Oliveira, Maria Joao

Subjects
Mathematical Physics, Mathematics - Functional Analysis, 60G55, 60J25, 47B39, 47B93, 81S05, 05A10, 05A40
Abstract

The paper describes known and new results about finite difference calculus on configuration spaces. We describe finite difference geometry on configuration spaces, connect finite difference operators with cannonical commutation relations, find explicit form for certain finite difference Markov generators on configuration spaces, and describe spaces of Newton series defined over the configuration spaces.

Published
2024

2. Analysis on the cone of discrete Radon measures

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Kuchling, Peter, Lytvynov, Eugene, and Oliveira, Maria Joao

Subjects
Mathematical Physics, Mathematics - Functional Analysis
Abstract

We study analysis on the cone of discrete Radon measures over a locally compact Polish space $X$. We discuss probability measures on the cone and the corresponding correlation measures and correlation functions on the sub-cone of finite discrete Radon measures over $X$. For this, we consider on the cone an analogue of the harmonic analysis on the configuration space developed in [12]. We also study elements of the difference calculus on the cone: we introduce discrete birth-and-death gradients and study the corresponding Dirichlet forms; finally, we discuss a system of polynomial functions on the cone which satisfy the binomial identity., Comment: 24 pages

Published
2023

6. Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial

Author

Tuttle, Katherine R, Hauske, Sibylle J, Canziani, Maria Eugenia, Caramori, Maria Luiza, Cherney, David, Cronin, Lisa, Heerspink, Hiddo J L, Hugo, Christian, Nangaku, Masaomi, Rotter, Ricardo Correa, Silva, Arnold, Shah, Shimoli V, Sun, Zhichao, Urbach, Dorothea, de Zeeuw, Dick, Rossing, Peter, SZETO, Cheuk Chun, Echeverri, Diego, Martin, Edouard, Yee, Ming Li, Wah, William, Wang, Ray, Chacko, Bobby, Swaminathan, Shriram, MacIsaac, Richard, Hashimura, Hikaru, Ward, Glenn, De Vusser, Katrien, Claes, Kathleen, Kuypers, Dirk, Meijers, Björn, Van Craenenbroeck, Amaryllis, Hilbrands, Robert, Debroye, Corinne, Wissing, Karl Martin, Jadoul, Michel, Demoulin, Nathalie, Treille De Grandsaigne, Serge, Beklevic, Ishak, Marcoux, Diane, Liénart, Fabienne, Daper, Claude, De Brouckere, Véronique, Heureux, Mercédès, Felicio, Joao, Felicio, Karem Mileo, Leite, Daniella, Melo, Franciane, Queiroz, Natercia, Souza, Ana Carolina, Vieira, Jocyelle, Franco, Roberto, Mendes, Adriana, Picolli, Giovana, Canani, Luis Henrique, Sartori, Carla, Valenti, Adriana, Eliaschewitz, Freddy, Bona, Renata, Franco, Denise, Ludovico Costa de Castro, Denise, Magalhaes, Vanessa, Oliveira, Marcelo, Sampaio, Célia Regina, Visconti, Guilherme, Halpern, Bruno, Nihei, Camila, Pessoa, Bruna, Seraphim, Carlos, Santos, Daniel, Brito, Claudia, Douverny, Joao, Colella, Marina, Gazeta, Cristina, Vercia, Monique, Watanabe, Renato, Temelkova, Theodora, Kjurkchiev, Dimo, Statkova, Silviya, Popov, Iliya, Radeva, Radosveta, Arabadzhiev, Lachezar, Binova, Mariya, Bosilkov, Aleksandar, Koleva-Stoicheva, Neli, Ivanov, Ivaylo, Ivanova, Zornitsa, Kotseva, Viktoria, Spasov, Petar, Tsvetkov, Ivaylo, Jolly, Shivinder, Bailey, Gordon, Ye, Zhiming, Niu, Jianying, Li, Hongmei, Wu, Qing, Liao, Bing, Hao, Chuanming, Lai, Lingyun, Xu, Yunyu, Zhang, Min, Li, Yiwen, Liu, Bo, Shao, Lina, Chen, Wei, Wu, Haishan, Pirchala, Marian, Skarpova, Iva, Hraskova, Marketa, Soukupova, Simoneta, Veberova, Lucie, Drasnar, Tomas, Falc, Matej, Racz, Blazej, Votocek, Stepan, Weissova, Danica, Syc-Krivanova, Lenka, Slezak, Dagmar, Kantola, Ilkka, Nieminen, Sakari, Anttonen, Milla, Taurio, Jyrki, Lahtela, Jorma, Tsimihodimos, Vasileios, Balafa, Olga, Dounousi, Evangelia, Sakkou, Sissy, Tentolouris, Nikolaos, Siafarikas, Christos, Siami, Evangelia, Doupis, Ioannis, Angelopoulos, Theodoros, Georgoulias, Christodoulos, Pall, Denes, Esze, Regina, Kobling, Tamas, Varadi, Zita, Zsiros, Noemi, Vass, Viktor, Balo, Timea, Csanyi, Erika, Ory, Ivan, Pall, Istvan, Patai, Valentina, Zeak, Zsuzsanna, Takacs, Istvan, Petho, Akos, Szili, Balazs, Koranyi, Laszlo, Bezzegh, Katalin, Pauer, Jozsef, Peterfai, Eva, Konyves, Laszlo, Szoke, Brigitta, Hajdu, Csaba, Kalman, Krisztina, Yadav, Raj, Saxena, Navneet, Bhattacharya, Meenakshi, Sharma, Bal, Thomas, Nihal, K, Felix Jebasingh, Kapoor, Nitin, Kurian, Mathews E., Paul, Jinson, Ramesh, Priyadharshini, Varghese, Sheeba, Shibusawa, Nobuyuki, Nishi, Hiroshi, Noritake, Nobuyasu, Oda, Takashi, Okamoto, Hideki, Kasuga, Hirotake, Hori, Hiroshi, Ito, Yukiko, Mizukoshi, Toshihiro, Ishii, Hideto, Han, Seung Hyeok, Kim, Hyung Woo, Oh, Kook-Hwan, Han, Seung Seok, Han, Sang Youb, Cha, Dae Ryong, Cha, Jin Joo, Kwon, Soon-Kil, Cho, Hyunjeong, Kim, Hye-Young, Kim, Sun Moon, Lee, Jung Pyo, Lee, Jeonghwan, Lee, Li Yuan, Chang, Meng Lee, Laang, Shian Tuck, Tan, Zhao Zhi, Ahmad Rosdi, Hajar, Mohammad Ismail, Siti Hafizah, Simatherai, Devamalar, Tay, Ju Fan, Wong, Eddie, Fook Sem, Yakob, Suryati, Abdul Sukur, Noorhafini, Anuar, Amalina, Md. Rasid, Syaliza, Mushaddik, Irma Liyana, Mustafar, Ruslinda, Abu Shamsi, Muhammad Yusuf, Fong, Voon Ken, Kamaruzaman, Lydia, Mohd, Rozita, Wan Daud, Wan Rohaslizan, Wan Hassan, Wan Hasnul Halimi, Ab Hamid, Suhaidarwani, Abdullah, Muhammad Nabil, Yusoff, Mohd Yusran, Ramanathan, G R Letchuman, Lee, Kim Yen, Wan Ismail, Wan Fadhilah, Morales Villegas, Enrique, Ramirez Baez, Rubria, Vital Lopez, Jorge, Arias Delgadillo, Cristhian, Herrera Marmolejo, Marisol, Parra Perez, Rosa, Alpizar Salazar, Melchor, Flores Montealegre, Ana, Galvan Magaña, Jose, Gutierrez Tlapale, Minerva, Reyes Munguia, Daniela, Witczak, Bartlomiej, Gøransson, Lasse, Strand Thorsen, Inga, Caringal, Clodoaido, Villardo, Mario, Toledo, Ronaldo, Dijamco, Emerlinda Fausto, De Asis, Norman Cornelio, Kuizon, Angelica, Catindig, Elizabeth Ann, Perez, Ronald, Aquitania, Grace, Pableo, Jimrie David, Sanchez, Jay Karlou, Czernecka, Ewa, Cegiel, Aleksandra, Knychas, Dorota, Ochnio, Malgorzata, Kuligowska-Jakubowska, Monika, Cesarz, Marek, Kowalewska-Celejewska, Milena, Masajtis-Zagajewska, Anna, Jankowski, Lukasz, Ojrzanowski, Marcin, Olszewska-Jander, Magdalena, Skokowska, Ewa, Giermakowska-Samek, Malgorzata, Luchowska, Elzbieta, Patkowska, Renata, Sekulska, Marzenna, Marczuk-Krynicka, Dorota, Marciniak, Andrzej, Barwijuk, Michal, Myslicki, Marcin, Siek, Michal, Wronska, Danuta, Tomsia-Goncerz, Jadwiga, Wronski, Krzysztof, Junik, Roman, Dzialak, Szymon, Kurlapska, Ewelina, Malecha, Wieslaw, Suwala, Szymon, Branco, Patrícia, Birne, Rita, Raposo, João, Ferreira, Marta, Alexandrino, Henrique, Alves, Helena, Correia, Sara, Oliveira, Maria João, Ramalho, Diogo, Tavares, Patricia, Coetzee, Kathleen, Blignaut, Sue, Viljoen, Winifred, Potgieter, Elsje, Malherbe, Elmien, Ortiz Arduán, Alberto, Goma Garcés, Elena, Pérez, María, Santamaría, Rafael, López López, Isabel, Pendón de Mier, Victoria, Rodelo Haad, Cristian, Marques, María, Domènech, Esther, Portoles, Josep Maria, Soler, María José, Agraz, Irene, Azancot, María Antonieta, Bermejo, Sheila, Bolufer, Mónica, López, Marina, Ramos, Natalia, Toapanta, Néstor, Cigarrán Guldris, Secundino, Primo, Juan Carlos, Pérez, Luis Enrique, Rebollido Fernández, María, Holmer, Helene, Bruchfeld, Annette, Rofors, Justus, Tengmark, Bengt-Olov, Wuerzner, Gregoire, Leanizbarrutia, Garazi, Ozturk, Savas, Guler, Nurana, Safak, Seda, Lee, Keung, Campbell, Stephen, Siddiqui, Imran, Abbasi, Nadia, Tahir, Faiza, Azizad, Masoud, Jackson, Timothy, Everhart, Brian, Oliver, Michael, Rust, William, Sniezek, Matthew, Arif, Ahmed, Syed, Mohammed, Bhasin, Nitin, Bien, Michael, Gallego, Claudio, Jamal, Aamir, Moghadam, Mojtaba, Rizvi, Abid, Rizvi, Amna, Rizvi, Syed, Wong, Christopher, Lucas, Kathryn, Buery, Andrea, Chang, Ku-Lang, Presswood, Claire, Smith, Justin, Doshi, Ankur, Parikh, Manish, Wallace, Jeannine, Krishna, Arvind, Daugherty, Heidi, Fearday, Aaron, Keller, Christopher, Meng, Jerry, Nielsen, Alexandra, Rovner, Sergio, Almeida, Javier, Marranzini, Benito, Selby, Lisa, Yablon, Zachary, Jean-Louis, Daphne, Kotzker, Wayne, Perez, Chabely, Richards, Marc, Rosario, Reinaldo, Marcus, Roy, Okechukwu, Chike, Ross, Dennis, Gromala, Rachel, Reed, Matthew, Weber, Lisa, Nazeer, Imran, Kumar, Prashant, Mir, Muhammad, Shea, Heidi, Hart, Amanda, Wiebel, Jaime, Kooienga, Laura, Newsome, Britt, Suyumova, Irina, Alvarez, German, Bireddy, Venkata, Lansang, Maria, Mandry, Jose, Freire, Maria, Herrera Albornoz, Oscarina, Desai, Anant, Gandhi, Dayan, Rajan, Sibu, Raymond, Louis, Posada, Jorge, Garcia-Mayol, Luis, Gutierrez-Alsina, Rodolfo, Fernandez, Juan, Bruce, Kendaling, Cuellar, Juan, Ranz y Alvarez, Maria, Bartolacci, Ines, Pautasso, Mauro, Stoppa, Daniela, Riella, Miguel, Barbosa, Maria, Harcsa, Eleonora, Gulati, Yuvraj, Savalia, Denish, Khetan, Prakash, Sinha, Dhananjay, R, Niranjan, K, Srinivas, Pazos, Fabiola, Gacutan-Liwag, Aretha, Duszynska, Malgorzata, Antkowiak-Piatyszek, Karolina, Konieczny, Grzegorz, Sidorowicz-Bialynicka, Anna, Ciesiolkiewicz-Wojcik, Agnieszka, Dwojak, Marek, Szymkowiak, Katarzyna, Gorczyca-Siudak, Daria, Janik-Palazzolo, Marzena, Siudak, Lukasz, Opiela, Jaroslaw, Iwanow, Dariusz, Solkiewicz, Monika, Sipinska-Surzynska, Malgorzata, Olszanecka - Glinianowicz, Magdalena, Rozmilowska, Izabela, Trokis, Julian, Prozesky, Hans, Burgess, Lesley, Cyster, Henry, Jordaan, Jurie, Mohamed, Hawa, Naude, Christina, Sitsila, Thembie, Mehta, Arvind, Mocherla, Bharat, Lee, Sungchun, Boren, Kenneth, Rudolph, Lance, Benjamin, Sabrina, Sugimoto, Danny, Hammoud, Jamal, Bakleh, Muhammad, Hashish, Yaseen, Da Costa, Jonathan, Gold, Marina, Majul, Claudio, Buscema, Juan, Gatto, Maria, Lombardi, Facundo, Paez, Olga, Puleio, Pablo, Alvarisqueta, Andrés, Pajon, Vanessa, Suarez, Gabriel, Hernandez Gauna, Adrian, Pereyra, Alejandro, Reig, Moira, Gelersztein, Elizabeth, Campestri, Gina, Gonzalez Santos, Maria, Sambresqui, Julieta, Catalano, Gustavo, Igarzabal, Cecilia, Vallejos, Augusto, Escobari, Claudio, Marchetto, Rocio, Chahin, Mariano, Aguilera, Andrea, Comes, Ana, Rodriguez Segade, Silvia, Baccaro, Claudia, Larrieu Lacoste, María Verónica, Saurral, Ruben, Cristino, Alberto, Dran, Dario, Koretzky, Martin, Ponti, Juan, Porto, Alejandro, Tenaglia, Yasmin, Maldonado, Natacha, Bertollo, Natalia, Van Perdeck, Verónica, Lopau, Kai, Wanner, Christoph, Berfelo, Florieke, Contzen, Christel, Arbi, Abdulwahab, Lee-Barkey, Young Hee, Maciejewska, Aleksandra, Arelin, Katrin, Haller, Hermann, Kaufeld, Jessica, Schmidt-Ott, Kai, Heinrichs, Sven, Krüger, Thilo, Gebauer, Chris, Paliege, Alexander, Henkel, Elena, Axthelm, Christoph, Derwahl, Karl-Michael, Trevisan, Roberto, Bellante, Rosalia, Borrella, Nicolò, Corsi, Anna, Gesualdo, Loreto, Ardillo, Teodora, Ficarella, Maria, Fikry, Sameh, Mazza, Giuseppe, Poirier, Lysane, Bajaj, Harpreet, Hatziagelaki, Erifili, Katopodis, Sokratis, Katsoudas, Spiros, Yamaura, Shuichi, Shikano, Tsutomu, Tosaki, Takahiro, Miho, Otoya, Tachibana, Naoki, Yumita, Wataru, Kado, Hiroshi, Villarreal Martinez, Jesus, Soto Miranda, Ernesto, Gonzalez Rodriguez, David, Panelo, Araceli, Santos, Telma, Martins, Ana, Mateus, Catarina, Teixeira e Costa, Fernando, Barreto, Sara, Silva Costa, Joana, Ferrer, Francisco, Silva, Joana, Awad, Ahmed, Khaleel, Shatha, Lustig, Ryan, Maharjan, Gajendra, Moya, Jaynier, Johnsingh, Amit, Acosta, Idalia, Newman, George, Buckle, Anita, and Hendon, Kendra

Published
2024
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7. Stirling operators in spatial combinatorics

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Lytvynov, Eugene, and Oliveira, Maria Joao

Subjects
Mathematics - Combinatorics, Mathematical Physics, Mathematics - Functional Analysis, Mathematics - Probability, Primary 11B73, 46G25, 47B39, 47B93, 81S05, Secondary 05A10, 05A19, 60G55
Abstract

We define and study a spatial (infinite-dimensional) counterpart of Stirling numbers. In classical combinatorics, the Pochhammer symbol $(m)_n$ can be extended from a natural number $m\in\mathbb N$ to the falling factorials $(z)_n=z(z-1)\dotsm (z-n+1)$ of an argument $z$ from $\mathbb F=\mathbb R\text{ or }\mathbb C$, and Stirling numbers of the first and second kinds are the coefficients of the expansions of $(z)_n$ through $z^k$, $k\leq n$ and vice versa. When taking into account spatial positions of elements in a locally compact Polish space $X$, we replace $\mathbb N$ by the space of configurations -- discrete Radon measures $\gamma=\sum_i\delta_{x_i}$ on $X$, where $\delta_{x_i}$ is the Dirac measure with mass at $x_i$.The spatial falling factorials $(\gamma)_n:=\sum_{i_1}\sum_{i_2\ne i_1}\dotsm\sum_{i_n\ne i_1,\dots, i_n\ne i_{n-1}}\delta_{(x_{i_1},x_{i_2},\dots,x_{i_n})}$ can be naturally extended to mappings $M^{(1)}(X)\ni\omega\mapsto (\omega)_n\in M^{(n)}(X)$, where $M^{(n)}(X)$ denotes the space of $\mathbb F$-valued, symmetric (for $n\ge2$) Radon measures on $X^n$. There is a natural duality between $M^{(n)}(X)$ and the space $\mathcal {CF}^{(n)}(X)$ of $\mathbb F$-valued, symmetric continuous functions on $X^n$ with compact support. The Stirling operators of the first and second kind, $\mathbf{s}(n,k)$ and $\mathbf{S}(n,k)$, are linear operators, acting between spaces $\mathcal {CF}^{(n)}(X)$ and $\mathcal {CF}^{(k)}(X)$ such that their dual operators, acting from $M^{(k)}(X)$ into $M^{(n)}(X)$, satisfy $(\omega)_n=\sum_{k=1}^n\mathbf{s}(n,k)^*\omega^{\otimes k}$ and $\omega^{\otimes n}=\sum_{k=1}^n\mathbf{S}(n,k)^*(\omega)_k$, respectively. We derive combinatorial properties of the Stirling operators, present their connections with a generalization of the Poisson point process and with the Wick ordering under the canonical commutation relations.

Published
2020
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8. Maturity-onset diabetes of the young in a large Portuguese cohort

Author

Santos Monteiro, Sílvia, da Silva Santos, Tiago, Fonseca, Liliana, Assunção, Guilherme, Lopes, Ana M., Duarte, Diana B., Soares, Ana Rita, Laranjeira, Francisco, Ribeiro, Isaura, Pinto, Eugénia, Rocha, Sónia, Barbosa Gouveia, Sofia, Vazquez-Mosquera, María Eugenia, Oliveira, Maria João, Borges, Teresa, and Cardoso, Maria Helena

Published
2023
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12. Sheffer homeomorphisms of spaces of entire functions in infinite dimensional analysis

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Lytvynov, Eugene, Oliveira, Maria Joao, and Streit, Ludwig

Subjects
Mathematics - Functional Analysis, Mathematics - Complex Variables
Abstract

For certain Sheffer sequences $(s_n)_{n=0}^\infty$ on $\mathbb C$, Grabiner (1988) proved that, for each $\alpha\in[0,1]$, the corresponding Sheffer operator $z^n\mapsto s_n(z)$ extends to a linear self-homeomorphism of $\mathcal E^{\alpha}_{\mathrm{min}}(\mathbb C)$, the Fr\'echet topological space of entire functions of order at most $\alpha$ and minimal type (when the order is equal to $\alpha>0$). In particular, every function $f\in \mathcal E^{\alpha}_{\mathrm{min}}(\mathbb C)$ admits a unique decomposition $f(z)=\sum_{n=0}^\infty c_n s_n(z)$, and the series converges in the topology of $\mathcal E^{\alpha}_{\mathrm{min}}(\mathbb C)$. Within the context of a complex nuclear space $\Phi$ and its dual space $\Phi'$, in this work we generalize Grabiner's result to the case of Sheffer operators corresponding to Sheffer sequences on $\Phi'$. In particular, for $\Phi=\Phi'=\mathbb C^n$ with $n\ge2$, we obtain the multivariate extension of Grabiner's theorem. Furthermore, for an Appell sequence on a general co-nuclear space $\Phi'$, we find a sufficient condition for the corresponding Sheffer operator to extend to a linear self-homeomorphism of $\mathcal E^{\alpha}_{\mathrm{min}}(\Phi')$ when $\alpha>1$. The latter result is new even in the one-dimensional case.

Published
2018
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14. An infinite dimensional umbral calculus

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Lytvynov, Eugene, and Oliveira, Maria Joao

Subjects
Mathematics - Functional Analysis, 05A40, 46E50, 60H40, 60G55
Abstract

The aim of this paper is to develop foundations of umbral calculus on the space $\mathcal D'$ of distributions on $\mathbb R^d$, which leads to a general theory of Sheffer polynomial sequences on $\mathcal D'$. We define a sequence of monic polynomials on $\mathcal D'$, a polynomial sequence of binomial type, and a Sheffer sequence. We present equivalent conditions for a sequence of monic polynomials on $\mathcal D'$ to be of binomial type or a Sheffer sequence, respectively. We also construct a lifting of a sequence of monic polynomials on $\mathbb R$ of binomial type to a polynomial sequence of binomial type on $\mathcal D'$, and a lifting of a Sheffer sequence on $\mathbb R$ to a Sheffer sequence on $\mathcal D'$. Examples of lifted polynomial sequences include the falling and rising factorials on $\mathcal D'$, Abel, Hermite, Charlier, and Laguerre polynomials on $\mathcal D'$. Some of these polynomials have already appeared in different branches of infinite dimensional (stochastic) analysis and played there a fundamental role.

Published
2017
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16. Machine Learning-Driven GLCM Analysis of Structural MRI for Alzheimer's Disease Diagnosis.

Author

Oliveira, Maria João, Ribeiro, Pedro, and Rodrigues, Pedro Miguel

Abstract

Background: Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative condition that increasingly impairs cognitive functions and daily activities. Given the incurable nature of AD and its profound impact on the elderly, early diagnosis (at the mild cognitive impairment (MCI) stage) and intervention are crucial, focusing on delaying disease progression and improving patients' quality of life. Methods: This work aimed to develop an automatic sMRI-based method to detect AD in three different stages, namely healthy controls (CN), mild cognitive impairment (MCI), and AD itself. For such a purpose, brain sMRI images from the ADNI database were pre-processed, and a set of 22 texture statistical features from the sMRI gray-level co-occurrence matrix (GLCM) were extracted from various slices within different anatomical planes. Different combinations of features and planes were used to feed classical machine learning (cML) algorithms to analyze their discrimination power between the groups. Results: The cML algorithms achieved the following classification accuracy: 85.2% for AD vs. CN, 98.5% for AD vs. MCI, 95.1% for CN vs. MCI, and 87.1% for all vs. all. Conclusions: For the pair AD vs. MCI, the proposed model outperformed state-of-the-art imaging source studies by 0.1% and non-imaging source studies by 4.6%. These results are particularly significant in the field of AD classification, opening the door to more efficient early diagnosis in real-world settings since MCI is considered a precursor to AD. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Nature Pleated Surfaces

Author

de Oliveira, Maria João, Crespo Osório, Filipa, Pisello, Anna Laura, Editorial Board Member, Hawkes, Dean, Editorial Board Member, Bougdah, Hocine, Editorial Board Member, Rosso, Federica, Editorial Board Member, Abdalla, Hassan, Editorial Board Member, Boemi, Sofia-Natalia, Editorial Board Member, Mohareb, Nabil, Editorial Board Member, Mesbah Elkaffas, Saleh, Editorial Board Member, Bozonnet, Emmanuel, Editorial Board Member, Pignatta, Gloria, Editorial Board Member, Mahgoub, Yasser, Editorial Board Member, De Bonis, Luciano, Editorial Board Member, Kostopoulou, Stella, Editorial Board Member, Pradhan, Biswajeet, Editorial Board Member, Abdul Mannan, Md., Editorial Board Member, Alalouch, Chaham, Editorial Board Member, O. Gawad, Iman, Editorial Board Member, Nayyar, Anand, Editorial Board Member, Amer, Mourad, Series Editor, Eloy, Sara, editor, Leite Viana, David, editor, Morais, Franklim, editor, and Vieira Vaz, Jorge, editor

Published
2021
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23. Surgical management of obstructing ureteral stones during pregnancy: A systematic review of different techniques.

Author

Laranjo-Tinoco, Catarina, Oliveira, Maria João, Araújo, Ana Sofia, Cardoso, Andreia, Oliveira, Carlos, Mota, Paulo, and Torres, João Pimentel

Subjects
*SURGICAL stents, *PREGNANT women, *URINARY calculi, *SURGICAL complications, *PREMATURE labor, *URETEROSCOPY
Abstract

Introduction: Renal colic is the most common non-obstetric cause of abdominal pain during pregnancy and is associated with a higher risk of complications in these women. When invasive treatment is required, options are temporary drainage with ureteral stent (JJ) or percutaneous nephrostomy (PCN), or immediate definitive treatment with ureteroscopy (URS). Our goal was to review the safety and efficacy of these procedures in treating urolithiasis during pregnancy. Methods: Adhering to the PRISMA checklist guidelines, we searched PubMed, Embase, and Scopus databases for articles on the efficacy and complications of the three procedures in pregnant women. The quality of evidence and risk of bias were evaluated using the Critical Appraisal Skills Programme and the Institute of Health Economics tools. Results: We included 45 articles, totaling 3424 interventions in pregnant women - 2188 URS, 719 JJ, and 517 PCN. URS was the most assessed procedure, with stone-free rates comparable to the non-pregnant patients. The most frequent complications were lower urinary symptoms and infections independently of the intervention. Obstetric complications for all interventions included 167 cases of preterm labor, resulting in 24 premature births. No statistically significant differences in post-operative complications were reported between the procedures in the few comparative studies. Conclusions: Despite the absence of high-quality studies, current evidence suggests that URS, JJ, and PCN are all safe and effective during pregnancy. As most patients submitted to temporary drainage require a second procedure post-delivery, primary URS appears more efficient. Therefore, it is the preferred option unless there are indications for temporary drainage. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Genetic architecture of congenital hypogonadotropic hypogonadism: insights from analysis of a Portuguese cohort.

Author

Carriço, Josianne Nunes, Gonçalves, Catarina Inês, Al-Naama, Asma, Syed, Najeeb, Aragüés, José Maria, Bastos, Margarida, Fonseca, Fernando, Borges, Teresa, Pereira, Bernardo Dias, Pignatelli, Duarte, Carvalho, Davide, Cunha, Filipe, Saavedra, Ana, Rodrigues, Elisabete, Saraiva, Joana, Ruas, Luisa, Vicente, Nuno, Martins, João Martin, Lages, Adriana De Sousa, and Oliveira, Maria João

Subjects
HEREDITY, DNA copy number variations, GENETIC testing, PORTUGUESE people, GENE frequency, KALLMANN syndrome
Abstract

STUDY QUESTION What is the contribution of genetic defects in Portuguese patients with congenital hypogonadotropic hypogonadism (CHH)? SUMMARY ANSWER Approximately one-third of patients with CHH were found to have a genetic cause for their disorder, with causal pathogenic and likely pathogenic germline variants distributed among 10 different genes; cases of oligogenic inheritance were also included. WHAT IS KNOWN ALREADY CHH is a rare and genetically heterogeneous disorder characterized by deficient production, secretion, or action of GnRH, LH, and FSH, resulting in delayed or absent puberty, and infertility. STUDY DESIGN, SIZE, DURATION Genetic screening was performed on a cohort of 81 Portuguese patients with CHH (36 with Kallmann syndrome and 45 with normosmic hypogonadotropic hypogonadism) and 263 unaffected controls. PARTICIPANTS/MATERIALS, SETTING, METHODS The genetic analysis was performed by whole-exome sequencing followed by the analysis of a virtual panel of 169 CHH-associated genes. The main outcome measures were non-synonymous rare sequence variants (population allele frequency <0.01) classified as pathogenic, likely pathogenic, and variants of uncertain significance (VUS). MAIN RESULTS AND THE ROLE OF CHANCE A genetic cause was identified in 29.6% of patients. Causal pathogenic and likely pathogenic variants were distributed among 10 of the analysed genes. The most frequently implicated genes were GNRHR , FGFR1 , ANOS1 , and CHD7. Oligogenicity for pathogenic and likely pathogenic variants was observed in 6.2% of patients. VUS and oligogenicity for VUS variants were observed in 85.2% and 54.3% of patients, respectively, but were not significantly different from that observed in controls. LARGE SCALE DATA N/A. LIMITATIONS, REASONS FOR CAUTION The identification of a large number of VUS presents challenges in interpretation and these may require reclassification as more evidence becomes available. Non-coding and copy number variants were not studied. Functional studies of the variants were not undertaken. WIDER IMPLICATIONS OF THE FINDINGS This study highlights the genetic heterogeneity of CHH and identified several novel variants that expand the mutational spectrum of the disorder. A significant proportion of patients remained without a genetic diagnosis, suggesting the involvement of additional genetic, epigenetic, or environmental factors. The high frequency of VUS underscores the importance of cautious variant interpretation. These findings contribute to the understanding of the genetic architecture of CHH and emphasize the need for further studies to elucidate the underlying mechanisms and identify additional causes of CHH. STUDY FUNDING/COMPETING INTEREST(S) This research was funded by the Portuguese Foundation for Science and Technology (grant numbers PTDC/SAU-GMG/098419/2008, UIDB/00709/2020, CEECINST/00016/2021/CP2828/CT0002, and 2020.04924.BD) and by Sidra Medicine—a member of the Qatar Foundation (grant number SDR400038). The authors declare no competing interests. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Polymer Measure: Varadhan's Renormalization Revisited

Author

Bock, Wolfgang, Oliveira, Maria João, da Silva, José Luis, and Streit, Ludwig

Subjects
Mathematical Physics, 28C20, 41A25, 60H40, 60J55, 60J65, 82D60
Abstract

Through chaos decomposition we improve the Varadhan estimate for the rate of convergence of the centered approximate self-intersection local time of planar Brownian motion., Comment: 5 pages

Published
2014
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29. Dynamical Widom-Rowlinson model and its mesoscopic limit

Author

Finkelshtein, Dmitri, Kondratiev, Yuri, Kutoviy, Oleksandr, and Oliveira, Maria Joao

Subjects
Mathematical Physics, Mathematics - Dynamical Systems, Nonlinear Sciences - Adaptation and Self-Organizing Systems, 70F45, 34A34, 37A60
Abstract

We consider the non-equilibrium dynamics for the Widom-Rowlinson model (without hard-core) in the continuum. The Lebowitz-Penrose-type scaling of the dynamics is studied and the system of the corresponding kinetic equations is derived. In the space-homogeneous case, the equilibrium points of this system are described. Their structure corresponds to the dynamical phase transition in the model. The bifurcation of the system is shown.

Published
2014
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31. Hábitos de consumo y satisfacción con las revistas electrónicas de los investigadores de las Universidades de Coimbra, León y Porto

Author

Rodríguez-Bravo, Blanca, Borges, Maria Manuel, Fernandes, Alberto Nuno Oliveira, Olea-Merino, Isabel, Oliveira, Maria João Carvalho de, Rodríguez-Bravo, Blanco, and Ribeiro, Fernanda

Subjects
GG. Curricula aspects., GH. Education., HN. e-journals.
Abstract

This is a study of the behavior, preferences and level of satisfaction of the academic communities of the Universities of Coimbra, Porto and Leon in relation to the use of electronic journals.With this aim, data and opinions from faculty undertaking research in differents fields of knowledge were gathered during surveys carried out in 2012. Frequent, intense use was noted, this being fundamentally directed towards research tasks. The average number of articles consulted per year was considerable, with clear differences being visible between the fields of Humanities, Social Sciences and Life and Health Sciences. The number of journal titles consulted regularly by faculty was found to be an average of almost ten, results that exceed the threshold found in other works

Published
2013

34. Contributors

Author

Abdallah, Yomna K., primary, Alonso, Natalia A., additional, Amez, Isabel, additional, Balo, Figen, additional, Baral, Sanchita, additional, Bonga, Danilo, additional, Chou, Loke-Ming, additional, Chua, Thia-Eng, additional, Estévez, Alberto T., additional, Gökgöz, Fazıl, additional, Gonzalez, Sergio, additional, Henshaw, Paul, additional, Hossain, Md. Faruque, additional, Khayyam, Umer, additional, Leitão, Carla, additional, Llamas, Bernardo, additional, Mabhaudhi, Tafadzwanashe, additional, Mpandeli, Sylvester, additional, Nhamo, Luxon, additional, Oliveira, Maria João de, additional, Ortega, Marcelo F., additional, Rato, Vasco, additional, Sadoughi, Arezou, additional, Sanchez-Martin, Laura, additional, Sua, Lutfu S., additional, Tafazzoli, Mohammadsoroush, additional, Ting, David S-K., additional, Wang, Xi, additional, Waseem, Sarah, additional, Xydis, George, additional, and Yalçın, Engin, additional

Published
2021
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38. Kawasaki dynamics in the continuum via generating functionals evolution

Author

Finkelshtein, Dmitri L., Kondratiev, Yuri G., and Oliveira, Maria Joao

Subjects
Mathematical Physics, 82C22, 46G20, 46E50
Abstract

We construct the time evolution of Kawasaki dynamics for a spatial infinite particle system in terms of generating functionals. This is carried out by an Ovsjannikov-type result in a scale of Banach spaces, which leads to a local (in time) solution. An application of this approach to Vlasov-type scaling in terms of generating functionals is considered as well., Comment: 13 pages

Published
2011

39. Markov evolutions and hierarchical equations in the continuum: II. Multicomponent systems

Author

Finkelshtein, Dmitri L., Kondratiev, Yuri G., and Oliveira, Maria João

Subjects
Mathematical Physics, 82C22, 60K35
Abstract

General birth-and-death as well as hopping stochastic dynamics of infinite multicomponent particle systems in the continuum are considered. We derive the corresponding evolution equations for quasi-observables and correlation functions. We also present sufficient conditions that allows us to consider these equations on suitable Banach spaces., Comment: 31 pages

Published
2011
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40. Self-repelling fractional Brownian motion - a generalized Edwards model for chain polymers

Author

Bornales, Jinky, Oliveira, Maria João, and Streit, Ludwig

Subjects
Mathematical Physics, 28C20, 60G15, 82D60
Abstract

We present an extension of the Edwards model for conformations of individual chain molecules in solvents in terms of fractional Brownian motion, and discuss the excluded volume effect on the end-to-end length of such trajectories or molecules., Comment: 14 pages

Published
2011
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41. Glauber dynamics in the continuum via generating functionals evolution

Author

Finkelshtein, Dmitri L., Kondratiev, Yuri G., and Oliveira, Maria João

Subjects
Mathematical Physics, 82C22, 46G20, 46E50
Abstract

We construct the time evolution for states of Glauber dynamics for a spatial infinite particle system in terms of generating functionals. This is carried out by an Ovsjannikov-type result in a scale of Banach spaces, leading to a local (in time) solution which, under certain initial conditions, might be extended to a global one. An application of this approach to Vlasov-type scaling in terms of generating functionals is considered as well., Comment: 24 pages

Published
2011
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42. Self-avoiding fractional Brownian motion - The Edwards model

Author

Grothaus, Martin, Oliveira, Maria João, da Silva, José Luis, and Streit, Ludwig

Subjects
Mathematical Physics, 60G15, 60G18, 60J55, 28C20, 46F25
Abstract

In this work we extend Varadhan's construction of the Edwards polymer model to the case of fractional Brownian motions in $\R^d$, for any dimension $d\geq 2$, with arbitrary Hurst parameters $H\leq 1/d$., Comment: 14 pages

Published
2010
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43. The fractional volatility model: No-arbitrage, leverage and risk measures

Author

Mendes, R. Vilela and Oliveira, Maria João

Subjects
Quantitative Finance - Pricing of Securities, Mathematics - Probability, Quantitative Finance - Statistical Finance
Abstract

Based on a criterium of mathematical simplicity and consistency with empirical market data, a stochastic volatility model has been obtained with the volatility process driven by fractional noise. Depending on whether the stochasticity generators of log-price and volatility are independent or are the same, two versions of the model are obtained with different leverage behavior. Here, the no-arbitrage and incompleteness properties of the model are studied. Some risk measures are also discussed in this framework., Comment: 12 pages latex

Published
2010

44. The fractional Poisson measure in infinite dimensions

Author

Oliveira, Maria Joao, Ouerdiane, Habib, da Silva, Jose Luis, and Mendes, R. Vilela

Subjects
Mathematics - Probability, Mathematical Physics, 28C20, 60G55
Abstract

The Mittag-Leffler function $E_{\alpha}$ being a natural generalization of the exponential function, an infinite-dimensional version of the fractional Poisson measure would have a characteristic functional \[ C_{\alpha}(\phi) :=E_{\alpha}(\int (e^{i\phi(x)}-1)d\mu (x)) \] which we prove to fulfill all requirements of the Bochner-Minlos theorem. The identity of the support of this new measure with the support of the infinite-dimensional Poisson measure ($\alpha =1$) allows the development of a fractional infinite-dimensional analysis modeled on Poisson analysis through the combinatorial harmonic analysis on configuration spaces. This setting provides, in particular, explicit formulas for annihilation, creation, and second quantization operators. In spite of the identity of the supports, the fractional Poisson measure displays some noticeable differences in relation to the Poisson measure, which may be physically quite significant., Comment: 16 pages

Published
2010

45. Intersection local times of independent fractional Brownian motions as generalized white noise functionals

Author

Oliveira, Maria Joao, da Silva, Jose Luis, and Streit, Ludwig

Subjects
Mathematics - Probability, Mathematical Physics, 60H40, 60G15, 60J55, 28C20, 46F25, 82D60
Abstract

In this work we present expansions of intersection local times of fractional Brownian motions in $\R^d$, for any dimension $d\geq 1$, with arbitrary Hurst coefficients in $(0,1)^d$. The expansions are in terms of Wick powers of white noises (corresponding to multiple Wiener integrals), being well-defined in the sense of generalized white noise functionals. As an application of our approach, a sufficient condition on $d$ for the existence of intersection local times in $L^2$ is derived, extending the results of D. Nualart and S. Ortiz-Latorre in "Intersection Local Time for Two Independent Fractional Brownian Motions" (J. Theoret. Probab.,20(4)(2007), 759-767) to different and more general Hurst coefficients., Comment: 28 pages

Published
2010
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46. Hydrodynamic limits for the free Kawasaki dynamics of continuous particle systems

Author

Kondratiev, Yuri G., Kuna, Tobias, Oliveira, Maria João, da Silva, José Luís, and Streit, Ludwig

Subjects
Mathematics - Probability, Mathematical Physics, 82C21, 60G55, 60J75, 37A60
Abstract

An infinite particle system of independent jumping particles in infinite volume is considered. Their construction is recalled,further properties are derived, the relation with hierarchical equations, Poissonian analysis, and second quantization are discussed. The hydrodynamic limit for a general initial distribution satisfying a mixing condition is derived. The long time asymptotic is computed under an extra assumption. The relation with constructions based on infinite volume limits is discussed.

Published
2009

48. Intersection local times of fractional Brownian motions with $H\in(0,1)$ as generalized white noise functionals

Author

Drumond, Custodia, Oliveira, Maria Joao, and da Silva, Jose Luis

Subjects
Mathematical Physics, 60H40, 60G15, 28C20, 46F25
Abstract

In $\R^d$, for any dimension $d\geq 1$, expansions of self-intersection local times of fractional Brownian motions with arbitrary Hurst coefficients in $(0,1)$ are presented. The expansions are in terms of Wick powers of white noises (corresponding to multiple Wiener integrals), being well-defined in the sense of generalized white noise functionals., Comment: 17 pages

Published
2008
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49. Markov evolutions and hierarchical equations in the continuum I. One-component systems

Author

Finkelshtein, Dmitri L., Kondratiev, Yuri G., and Oliveira, Maria Joao

Subjects
Mathematical Physics
Abstract

General birth-and-death as well as hopping stochastic dynamics of infinite particle systems in the continuum are considered. We derive corresponding evolution equations for correlation functions and generating functionals. General considerations are illustrated in a number of concrete examples of Markov evolutions appearing in applications., Comment: 47 pages

Published
2007
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50. Non-equilibrium stochastic dynamics of continuous systems and Bogoliubov generating functionals

Author

Kondratiev, Yuri G., Kuna, Tobias, and Oliveira, Maria Joao

Subjects
Mathematical Physics, 28C20, 46G20, 60K35, 82B21, 82C21, 82C22
Abstract

Combinatorial harmonic analysis techniques are used to develop new functional analysis methods based on Bogoliubov functionals. Concrete applications of the methods are presented, namely, the study of a non-equilibrium stochastic dynamics of continuous systems., Comment: 37 pages

Published
2005
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