44 results on '"Oldenhof, Helena"'
Search Results
2. Neuroendocrine Stress Response in Female and Male Youths With Conduct Disorder and Associations With Early Adversity
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Bernhard, Anka, Ackermann, Katharina, Martinelli, Anne, Chiocchetti, Andreas G., Vllasaliu, Leonora, González-Madruga, Karen, Batchelor, Molly, Raschle, Nora M., Oldenhof, Helena, Jansen, Lucres M.C., Kohls, Gregor, Konrad, Kerstin, Popma, Arne, Stadler, Christina, Fairchild, Graeme, and Freitag, Christine M.
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- 2022
- Full Text
- View/download PDF
3. START NOW: a cognitive behavioral skills training for adolescent girls with conduct or oppositional defiant disorder – a randomized clinical trial
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Stadler, Christina; https://orcid.org/0000-0003-2178-0635, Freitag, Christine M; https://orcid.org/0000-0001-9676-4782, Popma, Arne; https://orcid.org/0000-0003-2170-3023, Nauta‐Jansen, Lucres; https://orcid.org/0000-0001-8475-4050, Konrad, Kerstin; https://orcid.org/0000-0001-9039-2615, Unternaehrer, Eva, Ackermann, Katharina; https://orcid.org/0000-0001-6443-7680, Bernhard, Anka; https://orcid.org/0000-0001-8864-1360, Martinelli, Anne; https://orcid.org/0000-0002-7158-9778, Oldenhof, Helena; https://orcid.org/0000-0002-7210-1519, Gundlach, Malou, Kohls, Gregor; https://orcid.org/0000-0003-2408-2939, Prätzlich, Martin, Kieser, Meinhard, Limprecht, Ronald, Raschle, Nora Maria; https://orcid.org/0000-0002-3160-5999, Vriends, Noortje, Trestman, Robert L, Kirchner, Marietta, Kersten, Linda, Stadler, Christina; https://orcid.org/0000-0003-2178-0635, Freitag, Christine M; https://orcid.org/0000-0001-9676-4782, Popma, Arne; https://orcid.org/0000-0003-2170-3023, Nauta‐Jansen, Lucres; https://orcid.org/0000-0001-8475-4050, Konrad, Kerstin; https://orcid.org/0000-0001-9039-2615, Unternaehrer, Eva, Ackermann, Katharina; https://orcid.org/0000-0001-6443-7680, Bernhard, Anka; https://orcid.org/0000-0001-8864-1360, Martinelli, Anne; https://orcid.org/0000-0002-7158-9778, Oldenhof, Helena; https://orcid.org/0000-0002-7210-1519, Gundlach, Malou, Kohls, Gregor; https://orcid.org/0000-0003-2408-2939, Prätzlich, Martin, Kieser, Meinhard, Limprecht, Ronald, Raschle, Nora Maria; https://orcid.org/0000-0002-3160-5999, Vriends, Noortje, Trestman, Robert L, Kirchner, Marietta, and Kersten, Linda
- Abstract
Background Conduct disorder (CD) and oppositional defiant disorder (ODD) both convey a high risk for maladjustment later in life and are understudied in girls. Here, we aimed at confirming the efficacy of START NOW, a cognitive‐behavioral, dialectical behavior therapy‐oriented skills training program aiming to enhance emotion regulation skills, interpersonal and psychosocial adjustment, adapted for female adolescents with CD or ODD. Methods A total of 127 girls were included in this prospective, cluster randomized, multi‐center, parallel group, quasi‐randomized, controlled phase III trial, which tested the efficacy of START NOW (n = 72) compared with standard care (treatment as usual, TAU, n = 55). All female adolescents had a clinical diagnosis of CD or ODD, were 15.6 (±1.5) years on average (range: 12–20 years), and were institutionalized in youth welfare institutions. The two primary endpoints were the change in number of CD/ODD symptoms between (1) baseline (T1) and post‐treatment (T3), and (2) between T1 and 12‐week follow‐up (T4). Results Both treatment groups showed reduced CD/ODD symptoms at T3 compared with T1 (95% CI: START NOW = −4.87, −2.49; TAU = −4.94, −2.30). There was no significant mean difference in CD/ODD symptom reduction from T1 to T3 between START NOW and TAU (−0.056; 95% CI = −1.860, 1.749; Hedge's g = −0.011). However, the START NOW group showed greater mean symptom reduction from T1 to T4 (−2.326; 95% CI = −4.274, −0.378; Hedge's g = −0.563). Additionally, secondary endpoint results revealed a reduction in staff reported aggression and parent‐reported irritability at post assessment. Conclusions Although START NOW did not result in greater symptom reduction from baseline to post‐treatment compared with TAU, the START NOW group showed greater symptom reduction from baseline to follow‐up with a medium effect size, which indicates a clinically meaningful delayed treatment effect.
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- 2024
4. Investigating Sex Differences in Emotion Recognition, Learning, and Regulation Among Youths With Conduct Disorder
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Kohls, Gregor, Baumann, Sarah, Gundlach, Malou, Scharke, Wolfgang, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Kersten, Linda, Prätzlich, Martin, Oldenhof, Helena, Jansen, Lucres, van den Boogaard, Lisette, Smaragdi, Areti, Gonzalez-Madruga, Karen, Cornwell, Harriet, Rogers, Jack C., Pauli, Ruth, Clanton, Roberta, Baker, Rosalind, Bigorra, Aitana, Kerexeta-Lizeaga, Iñaki, Sesma-Pardo, Eva, Aguirregomoscorta-Menéndez, Fernando, Siklósi, Réka, Dochnal, Roberta, Kalogerakis, Zacharias, Pirlympou, Mara, Papadakos, Leonidas, Dikeos, Dimitris, Hervas, Amaia, Herpertz-Dahlmann, Beate, Fernández-Rivas, Aranzazu, Popma, Arne, Stadler, Christina, De Brito, Stephane A., Blair, James R., Freitag, Christine M., Fairchild, Graeme, and Konrad, Kerstin
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- 2020
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5. Baseline autonomic nervous system activity in female children and adolescents with conduct disorder: Psychophysiological findings from the FemNAT-CD study
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Oldenhof, Helena, Prätzlich, Martin, Ackermann, Katharina, Baker, Rosalind, Batchelor, Molly, Baumann, Sarah, Bernhard, Anka, Clanton, Roberta, Dikeos, Dimitris, Dochnal, Roberta, Fehlbaum, Lynn Valérie, Fernández-Rivas, Aranzazu, de Geus, Eco, Gonzalez, Karen, de Artaza-Lavesa, Maider González, Guijarro, Silvina, Gundlach, Malou, Herpertz-Dahlmann, Beate, Hervas, Amaia, Jansen, Lucres, Kersten, Linda, Kohls, Gregor, Konsta, Angeliki, Lazaratou, Helen, Kerexeta-Lizeaga, Iñaki, Martinelli, Anne, van Nimwegen, Tisse, Puzzo, Ignazio, Raschle, Nora Maria, Rogers, Jack, Siklósi, Réka, Smaragdi, Areti, Steppan, Martin, De Brito, Stephane, Fairchild, Graeme, Kieser, Meinhard, Konrad, Kerstin, Freitag, Christine, Stadler, Christina, and Popma, Arne
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- 2019
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6. Resting autonomic nervous system activity is unrelated to antisocial behaviour dimensions in adolescents: Cross-sectional findings from a European multi-centre study
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Prätzlich, Martin, Oldenhof, Helena, Steppan, Martin, Ackermann, Katharina, Baker, Rosalind, Batchelor, Molly, Baumann, Sarah, Bernhard, Anka, Clanton, Roberta, Dikeos, Dimitris, Dochnal, Roberta, Fehlbaum, Lynn Valérie, Fernández-Rivas, Aranzazu, González de Artaza-Lavesa, Maider, Gonzalez-Madruga, Karen, Guijarro, Silvina, Gundlach, Malou, Herpertz-Dahlmann, Beate, Hervas, Amaia, Jansen, Lucres, Kerexeta-Lizeaga, Iñaki, Kersten, Linda, Kirchner, Marietta, Kohls, Gregor, Konsta, Angeliki, Lazaratou, Helen, Martinelli, Anne, Menks, Willeke Martine, Puzzo, Ignazio, Raschle, Nora Maria, Rogers, Jack, Siklósi, Réka, Smaragdi, Areti, Vriends, Noortje, Konrad, Kerstin, De Brito, Stephane, Fairchild, Graeme, Kieser, Meinhard, Freitag, Christine M., Popma, Arne, and Stadler, Christina
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- 2019
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7. Risk Taking by Adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD): a Behavioral and Psychophysiological Investigation of Peer Influence
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Dekkers, Tycho J., Popma, Arne, Sonuga-Barke, Edmund J.S., Oldenhof, Helena, Bexkens, Anika, Jansen, Brenda R. J., and Huizenga, Hilde M.
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- 2020
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8. START NOW: a cognitive behavioral skills training for adolescent girls with conduct or oppositional defiant disorder – a randomized clinical trial.
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Stadler, Christina, Freitag, Christine M., Popma, Arne, Nauta‐Jansen, Lucres, Konrad, Kerstin, Unternaehrer, Eva, Ackermann, Katharina, Bernhard, Anka, Martinelli, Anne, Oldenhof, Helena, Gundlach, Malou, Kohls, Gregor, Prätzlich, Martin, Kieser, Meinhard, Limprecht, Ronald, Raschle, Nora M., Vriends, Noortje, Trestman, Robert L., Kirchner, Marietta, and Kersten, Linda
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RESEARCH ,CONFIDENCE intervals ,RESEARCH methodology ,PSYCHOSOCIAL functioning ,BEHAVIOR disorders ,PSYCHOLOGY of women ,OPPOSITIONAL defiant disorder in children ,AGGRESSION (Psychology) ,COGNITIVE therapy ,MOTOR ability ,SOCIAL disabilities ,LONGITUDINAL method ,ADOLESCENCE - Abstract
Background: Conduct disorder (CD) and oppositional defiant disorder (ODD) both convey a high risk for maladjustment later in life and are understudied in girls. Here, we aimed at confirming the efficacy of START NOW, a cognitive‐behavioral, dialectical behavior therapy‐oriented skills training program aiming to enhance emotion regulation skills, interpersonal and psychosocial adjustment, adapted for female adolescents with CD or ODD. Methods: A total of 127 girls were included in this prospective, cluster randomized, multi‐center, parallel group, quasi‐randomized, controlled phase III trial, which tested the efficacy of START NOW (n = 72) compared with standard care (treatment as usual, TAU, n = 55). All female adolescents had a clinical diagnosis of CD or ODD, were 15.6 (±1.5) years on average (range: 12–20 years), and were institutionalized in youth welfare institutions. The two primary endpoints were the change in number of CD/ODD symptoms between (1) baseline (T1) and post‐treatment (T3), and (2) between T1 and 12‐week follow‐up (T4). Results: Both treatment groups showed reduced CD/ODD symptoms at T3 compared with T1 (95% CI: START NOW = −4.87, −2.49; TAU = −4.94, −2.30). There was no significant mean difference in CD/ODD symptom reduction from T1 to T3 between START NOW and TAU (−0.056; 95% CI = −1.860, 1.749; Hedge's g = −0.011). However, the START NOW group showed greater mean symptom reduction from T1 to T4 (−2.326; 95% CI = −4.274, −0.378; Hedge's g = −0.563). Additionally, secondary endpoint results revealed a reduction in staff reported aggression and parent‐reported irritability at post assessment. Conclusions: Although START NOW did not result in greater symptom reduction from baseline to post‐treatment compared with TAU, the START NOW group showed greater symptom reduction from baseline to follow‐up with a medium effect size, which indicates a clinically meaningful delayed treatment effect. [ABSTRACT FROM AUTHOR]
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- 2024
- Full Text
- View/download PDF
9. START NOW: a cognitive behavioral skills training for adolescent girls with conduct or oppositional defiant disorder – a randomized clinical trial
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Stadler, Christina, primary, Freitag, Christine M., additional, Popma, Arne, additional, Nauta‐Jansen, Lucres, additional, Konrad, Kerstin, additional, Unternaehrer, Eva, additional, Ackermann, Katharina, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Oldenhof, Helena, additional, Gundlach, Malou, additional, Kohls, Gregor, additional, Prätzlich, Martin, additional, Kieser, Meinhard, additional, Limprecht, Ronald, additional, Raschle, Nora M., additional, Vriends, Noortje, additional, Trestman, Robert L., additional, Kirchner, Marietta, additional, and Kersten, Linda, additional
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- 2023
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10. Relational Aggression in Adolescents with Conduct Disorder: Sex Differences and Behavioral Correlates
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Ackermann, Katharina, Kirchner, Marietta, Bernhard, Anka, Martinelli, Anne, Anomitri, Chrysanthi, Baker, Rosalind, Baumann, Sarah, Dochnal, Roberta, Fernandez-Rivas, Aranzazu, Gonzalez-Madruga, Karen, Herpertz-Dahlmann, Beate, Hervas, Amaia, Jansen, Lucres, Kapornai, Kristina, Kersten, Linda, Kohls, Gregor, Limprecht, Ronald, Lazaratou, Helen, McLaughlin, Ana, Oldenhof, Helena, Rogers, Jack C., Siklósi, Réka, Smaragdi, Areti, Vivanco-Gonzalez, Esther, Stadler, Christina, Fairchild, Graeme, Popma, Arne, De Brito, Stephane A., Konrad, Kerstin, and Freitag, Christine M.
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- 2019
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11. Linking heart rate variability to psychological health and brain structure in adolescents with and without conduct disorder
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Cubillo, Ana, primary, Tkalcec, Antonia, additional, Oldenhof, Helena, additional, Unternaehrer, Eva, additional, Raschle, Nora, additional, Kohls, Gregor, additional, Nauta-Jansen, Lucres, additional, Hervas, Amaia, additional, Fernandez-Rivas, Aranzazu, additional, Konrad, Kerstin, additional, Popma, Arne, additional, Freitag, Christine, additional, de Brito, Stephane, additional, Fairchild, Graeme, additional, and Stadler, Christina, additional
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- 2023
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12. Neurobiological correlates of antisociality across adolescence and young adulthood: a multi-sample, multi-method study
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Leerstoel Branje, Adolescent development: Characteristics and determinants, Blankenstein, Neeltje E., De Rooij, Mark, Van Ginkel, Joost, Wilderjans, Tom F., De Ruigh, Esther L., Oldenhof, Helena C., Zijlmans, Josjan, Jambroes, Tijs, Platje, Evelien, De Vries-bouw, Marjan, Branje, Susan, Meeus, Wim H. J., Vermeiren, Robert R. J. M., Popma, Arne, Jansen, Lucres M. C., Leerstoel Branje, Adolescent development: Characteristics and determinants, Blankenstein, Neeltje E., De Rooij, Mark, Van Ginkel, Joost, Wilderjans, Tom F., De Ruigh, Esther L., Oldenhof, Helena C., Zijlmans, Josjan, Jambroes, Tijs, Platje, Evelien, De Vries-bouw, Marjan, Branje, Susan, Meeus, Wim H. J., Vermeiren, Robert R. J. M., Popma, Arne, and Jansen, Lucres M. C.
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- 2023
13. Linking heart rate variability to psychological health and brain structure in adolescents with and without conduct disorder
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Cubillo, Ana; https://orcid.org/0000-0001-5657-7341, Tkalcec, Antonia; https://orcid.org/0000-0003-2872-5882, Oldenhof, Helena; https://orcid.org/0000-0002-7210-1519, Unternaehrer, Eva, Raschle, Nora; https://orcid.org/0000-0002-3160-5999, Kohls, Gregor; https://orcid.org/0000-0003-2408-2939, Nauta-Jansen, Lucres, Hervas, Amaia, Fernández-Rivas, Aranzazu, Konrad, Kerstin; https://orcid.org/0000-0001-9039-2615, Popma, Arne; https://orcid.org/0000-0003-2170-3023, Freitag, Christine; https://orcid.org/0000-0001-9676-4782, De Brito, Stephane; https://orcid.org/0000-0002-9082-6185, Fairchild, Graeme; https://orcid.org/0000-0001-7814-9938, Stadler, Christina; https://orcid.org/0000-0003-2178-0635, Cubillo, Ana; https://orcid.org/0000-0001-5657-7341, Tkalcec, Antonia; https://orcid.org/0000-0003-2872-5882, Oldenhof, Helena; https://orcid.org/0000-0002-7210-1519, Unternaehrer, Eva, Raschle, Nora; https://orcid.org/0000-0002-3160-5999, Kohls, Gregor; https://orcid.org/0000-0003-2408-2939, Nauta-Jansen, Lucres, Hervas, Amaia, Fernández-Rivas, Aranzazu, Konrad, Kerstin; https://orcid.org/0000-0001-9039-2615, Popma, Arne; https://orcid.org/0000-0003-2170-3023, Freitag, Christine; https://orcid.org/0000-0001-9676-4782, De Brito, Stephane; https://orcid.org/0000-0002-9082-6185, Fairchild, Graeme; https://orcid.org/0000-0001-7814-9938, and Stadler, Christina; https://orcid.org/0000-0003-2178-0635
- Abstract
AimsHeart rate variability (HRV) measures have been suggested in healthy individuals as a potential index of self-regulation skills, which include both cognitive and emotion regulation aspects. Studies in patients with a range of psychiatric disorders have however mostly focused on the potential association between abnormally low HRV at rest and specifically emotion regulation difficulties. Emotion regulation deficits have been reported in patients with Conduct Disorder (CD) however, the association between these emotion regulation deficits and HRV measures has yet to be fully understood. This study investigates (i) the specificity of the association between HRV and emotion regulation skills in adolescents with and without CD and (ii) the association between HRV and grey matter brain volumes in key areas of the central autonomic network which are involved in self-regulation processes, such as insula, lateral/medial prefrontal cortices or amygdala.MethodsRespiratory sinus arrhythmia (RSA) measures of HRV were collected from adolescents aged between 9–18 years (693 CD (427F)/753 typically developing youth (TD) (500F)), as part of a European multi-site project (FemNAT-CD). The Inverse Efficiency Score, a speed-accuracy trade-off measure, was calculated to assess emotion and cognitive regulation abilities during an Emotional Go/NoGo task. The association between RSA and task performance was tested using multilevel regression models. T1-weighted structural MRI data were included for a subset of 577 participants (257 CD (125F); 320 TD (186F)). The CerebroMatic toolbox was used to create customised Tissue Probability Maps and DARTEL templates, and CAT12 to segment brain images, followed by a 2 × 2 (sex × group) full factorial ANOVA with RSA as regressor of interest.ResultsThere were no significant associations between RSA and task performance, neither during emotion regulation nor during cognitive regulation trials. RSA was however positively correlated with regional grey
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- 2023
14. Analysis code for: Neurobiological correlates of antisociality across adolescence and young adulthood: A multi-sample, multi-method study
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Blankenstein, Neeltje, de Rooij, Mark, van Ginkel, Joost, Wilderjans, Tom, de Ruigh, Esther, Oldenhof, Helena, Zijlmans, Josjan, Jambroes, Tijs, Platje, Evelien, de Vries-Bouw, Marjan, Branje, Susan, Meeus, Wim, Vermeiren, Robert, Popma, Arne, and Nauta-Jansen, Lucres
- Abstract
Analysis code belonging to 'Neurobiological correlates of antisociality across adolescence and young adulthood: A multi-sample, multi-method study', Blankenstein et al.
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- 2022
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15. Restorative law from a neurobiological developmental perspective
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Jansen, LMC, Oldenhof, Helena, Claessen, Jacques, and van Hoek, Anneke
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Binnen het herstelrecht bestaat de mogelijkheid dat slachtoffers en daders los van de strafzaak met elkaar in gesprek gaan over de gepleegde misdaad en de gevolgen daarvan. Deze dialoog is primair gericht op emotioneel en relationeel herstel. Deze herstelrechtelijke procedures sluiten goed aan bij de toegenomen aandacht voor en bij de behoeften van slachtoffers. Bovendien blijken deze procedures effectiever te zijn in termen van duurzame conflictoplossing en recidivereductie dan het reguliere strafproces. In dit hoofdstuk proberen we vanuit een neurobiologisch ontwikkelingsperspectief nader te in te gaan op de vraag waarom herstelrecht een effectieve methode kan zijn om de relationeel-emotionele gevolgen van een delict te beperken of te herstellen en recidive te voorkomen en waar men rekening mee dient te houden bij de overweging om herstelrecht toe te passen.
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- 2022
16. Understanding the psychophysiology of Antisocial Behavior in Girls
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Oldenhof, Helena Catharina, Popma, Arne, Vermeiren, R.R.J.M., and Nauta-Jansen, L.M.C.
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Conduct Disorder ,sex differences ,antisociaal gedrag ,psychofysiology ,Conduct Disorder, antisocial behavior, sex differences, psychophysiology, autonomic nervous systsem ,antisocial behavior ,autonomic nervous systsem ,sekse verschillen ,Conduct Disorder, antisociaal gedrag, sekse verschillen, psychofysiology, autonome zenuwstelsel ,autonome zenuwstelsel ,psychophysiology - Abstract
This thesis aimed to increase the understanding of the mechanisms underlying antisocial behavior in girls. Therefore, we investigated autonomic nervous systsem functioning in a large sample of boys and girls, with and without conduct disorder. First, we assessed baseline ANS activity.,The studies in chapters 2 and 3 suggest that: baseline ANS activity is not related to CD in boys and girls, whereas reduced baseline parasympathetic activity is related specifically to internalizing problems in girls with CD, and increased RR may be a biomarker for CD in girls. Second, we assessed ANS responsivity to different challenges (emotion processing, fear anticipation, psychosocial stress), as decreased ANS responsivity has been previously found the be related to CD. In chapter 4 we observed a decrease in HR during the sad film clips. However, after controlling for covariates, HR deceleration did not differ significantly between girls and boys with and without CD and TDC. As for RSA, we observed an increased response in girls and boys with CD as compared to TDCs, suggesting aberrant parasympathetic responding during emotion processing in CD. However, findings should be interpreted cautiously since we found the aberrant parasympathetic response only during one of the two film clips, and the effect size was small. In chapter 5, we investigated ANS responsivity during fear anticipation. This study suggests a diminished threat sensitivity in CD, and supports the notion that fearlessness is one of the mechanisms underlying antisocial behavior in girls and boys. In Chapter 6 we presented the Trier Social Stress Test (TSST). We found a diminished response in HR and SNS activity, and an increased response in PNS activity in girls and boys with CD as compared to TDCs. Thus, in line with previous studies, we found evidence for blunted autonomic stress-responding in CD, providing further support for fearlessness as the potential mechanism underlying antisocial behavior in youths. Furthermore, this study suggests that impaired responding to psychosocial stress characterizes CD, irrespective of sex, and its clinical phenotype.
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- 2021
17. Machine learning classification of conduct disorder with high versus low levels of callous-unemotional traits based on facial emotion recognition abilities
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Pauli, Ruth, primary, Kohls, Gregor, additional, Tino, Peter, additional, Rogers, Jack C., additional, Baumann, Sarah, additional, Ackermann, Katharina, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Jansen, Lucres, additional, Oldenhof, Helena, additional, Gonzalez-Madruga, Karen, additional, Smaragdi, Areti, additional, Gonzalez-Torres, Miguel Angel, additional, Kerexeta-Lizeaga, Iñaki, additional, Boonmann, Cyril, additional, Kersten, Linda, additional, Bigorra, Aitana, additional, Hervas, Amaia, additional, Stadler, Christina, additional, Fernandez-Rivas, Aranzazu, additional, Popma, Arne, additional, Konrad, Kerstin, additional, Herpertz-Dahlmann, Beate, additional, Fairchild, Graeme, additional, Freitag, Christine M., additional, Rotshtein, Pia, additional, and De Brito, Stephane A., additional
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- 2021
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18. Neurobiological correlates of antisociality across adolescence and young adulthood: a multi-sample, multi-method study
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Blankenstein, Neeltje E., primary, de Rooij, Mark, additional, van Ginkel, Joost, additional, Wilderjans, Tom F., additional, de Ruigh, Esther L., additional, Oldenhof, Helena C., additional, Zijlmans, Josjan, additional, Jambroes, Tijs, additional, Platje, Evelien, additional, de Vries-Bouw, Marjan, additional, Branje, Susan, additional, Meeus, Wim H. J., additional, Vermeiren, Robert R. J. M., additional, Popma, Arne, additional, and Jansen, Lucres M. C., additional
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- 2021
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19. Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder
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Konrad, Kerstin, primary, Kohls, Gregor, additional, Baumann, Sarah, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Ackermann, Katharina, additional, Smaragdi, Areti, additional, Gonzalez‐Madruga, Karen, additional, Wells, Amy, additional, Rogers, Jack C., additional, Pauli, Ruth, additional, Clanton, Roberta, additional, Baker, Rosalind, additional, Kersten, Linda, additional, Prätzlich, Martin, additional, Oldenhof, Helena, additional, Jansen, Lucres, additional, Kleeven, Anneke, additional, Bigorra, Aitana, additional, Hervas, Amaia, additional, Kerexeta‐Lizeaga, Iñaki, additional, Sesma‐Pardo, Eva, additional, Angel Gonzalez‐Torres, Miguel, additional, Siklósi, Réka, additional, Dochnal, Roberta, additional, Kalogerakis, Zacharias, additional, Pirlympou, Mara, additional, Papadakos, Leonidas, additional, Cornwell, Harriet, additional, Scharke, Wolfgang, additional, Dikeos, Dimitris, additional, Fernández‐Rivas, Aranzazu, additional, Popma, Arne, additional, Stadler, Christina, additional, Herpertz‐Dahlmann, Beate, additional, De Brito, Stephane A., additional, Fairchild, Graeme, additional, and Freitag, Christine M., additional
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- 2021
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20. Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder
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Konrad, Kerstin, Kohls, Gregor, Baumann, Sarah, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Smaragdi, Areti, Gonzalez-Madruga, Karen, Wells, Amy, Rogers, Jack C., Pauli, Ruth, Clanton, Roberta, Baker, Rosalind, Kersten, Linda, Prätzlich, Martin, Oldenhof, Helena, Jansen, Lucres, Kleeven, Anneke, Bigorra, Aitana, Hervás, Amaia, Kerexeta-Lizeaga, Iñaki, Sesma-Pardo, Eva, Gonzalez-Torres, Miguel Angel, Siklósi, Réka, Dochnal, Roberta, Kalogerakis, Zacharias, Pirlympou, Mara, Papadakos, Leonidas, Cornwell, Harriet, Scharke, Wolfgang, Dikeos, Dimitris, Fernández-Rivas, Aranzazu, Popma, Arne, Stadler, Christina, Herpertz-Dahlmann, Beate, De Brito, Stephane A., Fairchild, Graeme, Freitag, Christine M., Konrad, Kerstin, Kohls, Gregor, Baumann, Sarah, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Smaragdi, Areti, Gonzalez-Madruga, Karen, Wells, Amy, Rogers, Jack C., Pauli, Ruth, Clanton, Roberta, Baker, Rosalind, Kersten, Linda, Prätzlich, Martin, Oldenhof, Helena, Jansen, Lucres, Kleeven, Anneke, Bigorra, Aitana, Hervás, Amaia, Kerexeta-Lizeaga, Iñaki, Sesma-Pardo, Eva, Gonzalez-Torres, Miguel Angel, Siklósi, Réka, Dochnal, Roberta, Kalogerakis, Zacharias, Pirlympou, Mara, Papadakos, Leonidas, Cornwell, Harriet, Scharke, Wolfgang, Dikeos, Dimitris, Fernández-Rivas, Aranzazu, Popma, Arne, Stadler, Christina, Herpertz-Dahlmann, Beate, De Brito, Stephane A., Fairchild, Graeme, and Freitag, Christine M.
- Abstract
Background: Conduct disorder (CD) rarely occurs alone but is typically accompanied by comorbid psychiatric disorders, which complicates the clinical presentation and treatment of affected youths. The aim of this study was to investigate sex differences in comorbidity pattern in CD and to systematically explore the ‘gender paradox’ and ‘delayed-onset pathway’ hypotheses of female CD. Methods: As part of the FemNAT-CD multisite study, semistructured clinical interviews and rating scales were used to perform a comprehensive phenotypic characterization of 454 girls and 295 boys with CD (9–18 years), compared to 864 sex- and age-matched typically developing controls. Results: Girls with CD exhibited higher rates of current major depression, anxiety disorders, post-traumatic stress disorder and borderline personality disorder, whereas boys with CD had higher rates of current attention-deficit/hyperactivity disorder. In line with the ‘gender paradox’ hypothesis, relative to boys, girls with CD showed significantly more lifetime psychiatric comorbidities (incl. Alcohol Use Disorder), which were accompanied by more severe CD symptoms. Female and male youths with CD also differed significantly in their CD symptom profiles and distribution of age-of-onset subtypes of CD (i.e. fewer girls with childhood-onset CD). In line with the ‘delayed-onset pathway’ hypothesis, girls with adolescent-onset CD showed similar levels of dimensional psychopathology like boys with childhood-onset CD, while boys with adolescent-onset CD had the lowest levels of internalizing psychopathology. Conclusions: Within the largest study of CD in girls performed to date, we found compelling evidence for sex differences in comorbidity patterns and clinical presentation of CD. Our findings further support aspects of the ‘gender paradox’ and ‘delayed-onset pathway’ hypotheses by showing that girls with CD had higher rates of comorbid lifetime mental disorders and functional impairments, and they usually deve
- Published
- 2021
21. Maturation of the Cardiac Autonomic Nervous System Activity in Children and Adolescents
- Author
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Harteveld, Lisette M., primary, Nederend, Ineke, additional, ten Harkel, Arend D. J., additional, Schutte, Nienke M., additional, de Rooij, Susanne R., additional, Vrijkotte, Tanja G. M., additional, Oldenhof, Helena, additional, Popma, Arne, additional, Jansen, Lucres M. C., additional, Suurland, Jill, additional, Swaab, Hanna, additional, de Geus, Eco J. C., additional, Prätzlich, Martin, additional, Ackermann, Katharina, additional, Baker, Rosalind, additional, Batchelor, Molly, additional, Baumann, Sarah, additional, Bernhard, Anka, additional, Clanton, Roberta, additional, Dikeos, Dimitris, additional, Dochnal, Roberta, additional, Fehlbaum, Lynn Valérie, additional, Fernández‐Rivas, Aranzazu, additional, Gonzalez, Karen, additional, González de Artaza‐Lavesa, Maider, additional, Guijarro, Silvina, additional, Gundlach, Malou, additional, Herpertz‐Dahlmann, Beate, additional, Hervas, Amaia, additional, Kersten, Linda, additional, Kohls, Gregor, additional, Konsta, Angeliki, additional, Lazaratou, Helen, additional, Kerexeta‐Lizeaga, Iñaki, additional, Martinelli, Anne, additional, van Nimwegen, Tisse, additional, Puzzo, Ignazio, additional, Raschle, Nora Maria, additional, Rogers, Jack, additional, Siklósi, Réka, additional, Smaragdi, Areti, additional, Steppan, Martin, additional, De Brito, Stephane, additional, Fairchild, Graeme, additional, Kieser, Meinhard, additional, Konrad, Kerstin, additional, Freitag, Christine, additional, and Stadler, Christina, additional
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- 2021
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22. Neuropsychological Subgroups of Emotion Processing in Youths With Conduct Disorder
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Kohls, Gregor, primary, Fairchild, Graeme, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Smaragdi, Areti, additional, Gonzalez-Madruga, Karen, additional, Wells, Amy, additional, Rogers, Jack C., additional, Pauli, Ruth, additional, Oldenhof, Helena, additional, Jansen, Lucres, additional, Rhijn, Arthur van, additional, Kersten, Linda, additional, Alfano, Janine, additional, Baumann, Sarah, additional, Herpertz-Dahlmann, Beate, additional, Vetro, Agnes, additional, Lazaratou, Helen, additional, Hervas, Amaia, additional, Fernández-Rivas, Aranzazu, additional, Popma, Arne, additional, Stadler, Christina, additional, De Brito, Stephane A., additional, Freitag, Christine M., additional, and Konrad, Kerstin, additional
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- 2020
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23. Psychophysiological responses to sadness in girls and boys with conduct disorder.
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Oldenhof, Helena, primary, Jansen, Lucres, additional, Ackermann, Katharina, additional, Baker, Rosalind, additional, Batchelor, Molly, additional, Baumann, Sarah, additional, Bernhard, Anka, additional, Clanton, Roberta, additional, Dochnal, Roberta, additional, Fehlbaum, Lynn Valérie, additional, Fernandez-Rivas, Aranzazu, additional, Goergen, Sarah, additional, Gonzalez de Artaza-Lavesa, Maider, additional, Gonzalez-Madruga, Karen, additional, Gonzalez-Torres, Miguel Angel, additional, Gundlach, Malou, additional, Lotte van der Hoeven, Mara, additional, Kalogerakis, Zacharias, additional, Kapornai, Krisztina, additional, Kieser, Meinhard, additional, Konsta, Angeliki, additional, Martinelli, Anne, additional, Pauli, Ruth, additional, Rogers, Jack, additional, Smaragdi, Areti, additional, Sesma-Pardo, Eva, additional, Siklósi, Réka, additional, Steppan, Martin, additional, Tsiakoulia, Foteini, additional, Vermeiren, Robert, additional, Vriends, Noortje, additional, Werner, Marleen, additional, Herpertz-Dahlmann, Beate, additional, Kohls, Gregor, additional, De Brito, Stephane, additional, Konrad, Kerstin, additional, Stadler, Christina, additional, Fairchild, Graeme, additional, Freitag, Christine M., additional, and Popma, Arne, additional
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- 2020
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24. Sex differences in psychiatric comorbidity and clinical presentation in youths with conduct disorder.
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Konrad, Kerstin, Kohls, Gregor, Baumann, Sarah, Bernhard, Anka, Martinelli, Anne, Ackermann, Katharina, Smaragdi, Areti, Gonzalez‐Madruga, Karen, Wells, Amy, Rogers, Jack C., Pauli, Ruth, Clanton, Roberta, Baker, Rosalind, Kersten, Linda, Prätzlich, Martin, Oldenhof, Helena, Jansen, Lucres, Kleeven, Anneke, Bigorra, Aitana, and Hervas, Amaia
- Subjects
RESEARCH methodology ,BORDERLINE personality disorder ,INTERVIEWING ,POST-traumatic stress disorder ,BEHAVIOR disorders in children ,SEX distribution ,COMPARATIVE studies ,ATTENTION-deficit hyperactivity disorder ,MENTAL depression ,AGE factors in disease ,PATHOLOGICAL psychology ,ANXIETY ,COMORBIDITY - Abstract
Background: Conduct disorder (CD) rarely occurs alone but is typically accompanied by comorbid psychiatric disorders, which complicates the clinical presentation and treatment of affected youths. The aim of this study was to investigate sex differences in comorbidity pattern in CD and to systematically explore the 'gender paradox' and 'delayed‐onset pathway' hypotheses of female CD. Methods: As part of the FemNAT‐CD multisite study, semistructured clinical interviews and rating scales were used to perform a comprehensive phenotypic characterization of 454 girls and 295 boys with CD (9–18 years), compared to 864 sex‐ and age‐matched typically developing controls. Results: Girls with CD exhibited higher rates of current major depression, anxiety disorders, post‐traumatic stress disorder and borderline personality disorder, whereas boys with CD had higher rates of current attention‐deficit/hyperactivity disorder. In line with the 'gender paradox' hypothesis, relative to boys, girls with CD showed significantly more lifetime psychiatric comorbidities (incl. Alcohol Use Disorder), which were accompanied by more severe CD symptoms. Female and male youths with CD also differed significantly in their CD symptom profiles and distribution of age‐of‐onset subtypes of CD (i.e. fewer girls with childhood‐onset CD). In line with the 'delayed‐onset pathway' hypothesis, girls with adolescent‐onset CD showed similar levels of dimensional psychopathology like boys with childhood‐onset CD, while boys with adolescent‐onset CD had the lowest levels of internalizing psychopathology. Conclusions: Within the largest study of CD in girls performed to date, we found compelling evidence for sex differences in comorbidity patterns and clinical presentation of CD. Our findings further support aspects of the 'gender paradox' and 'delayed‐onset pathway' hypotheses by showing that girls with CD had higher rates of comorbid lifetime mental disorders and functional impairments, and they usually developed CD during adolescence. These novel data on sex‐specific clinical profiles of CD will be critical in informing intervention and prevention programmes. [ABSTRACT FROM AUTHOR]
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- 2022
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25. Positive and negative parenting in conduct disorder with high versus low levels of callous–unemotional traits
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Pauli, Ruth, primary, Tino, Peter, additional, Rogers, Jack C., additional, Baker, Rosalind, additional, Clanton, Roberta, additional, Birch, Philippa, additional, Brown, Abigail, additional, Daniel, Gemma, additional, Ferreira, Lisandra, additional, Grisley, Liam, additional, Kohls, Gregor, additional, Baumann, Sarah, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Ackermann, Katharina, additional, Lazaratou, Helen, additional, Tsiakoulia, Foteini, additional, Bali, Panagiota, additional, Oldenhof, Helena, additional, Jansen, Lucres, additional, Smaragdi, Areti, additional, Gonzalez-Madruga, Karen, additional, Gonzalez-Torres, Miguel Angel, additional, Gonzalez de Artaza-Lavesa, Maider, additional, Steppan, Martin, additional, Vriends, Noortje, additional, Bigorra, Aitana, additional, Siklosi, Reka, additional, Ghosh, Sreejita, additional, Bunte, Kerstin, additional, Dochnal, Roberta, additional, Hervas, Amaia, additional, Stadler, Christina, additional, Fernandez-Rivas, Aranzazu, additional, Fairchild, Graeme, additional, Popma, Arne, additional, Dikeos, Dimitris, additional, Konrad, Kerstin, additional, Herpertz-Dahlmann, Beate, additional, Freitag, Christine M., additional, Rotshtein, Pia, additional, and De Brito, Stephane A., additional
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- 2020
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26. Gedragsstoornissen
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Oldenhof, Helena, Jansen, LMC, Popma, Arne, van Amelsfoort, Therese, Bekker, Marrie, van Mens-Verhulst, Janneke, Olff, Miranda, Pediatric surgery, VU University medical center, Amsterdam Reproduction & Development (AR&D), and APH - Mental Health
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- 2019
27. Erratum to: START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: Study protocol for a clusterrandomised controlled trial [BMC Trials. 17, (2016)(568)] DOI: 10.1186/s13063-016-1705-6
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Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert L., Stadler, Christina, APH - Mental Health, Pediatric surgery, Amsterdam Reproduction & Development (AR&D), and Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention
- Abstract
The original publication [1] contains a typographical typo in the Author's contributions section: "CS wrote the grant application." The correct sentence is: "CF coordinates the FemNAT-CD FP7 research project."
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- 2017
28. Erratum to:START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: Study protocol for a clusterrandomised controlled trial [BMC Trials. 17, (2016)(568)] DOI: 10.1186/s13063-016-1705-6
- Author
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Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert L., and Stadler, Christina
- Abstract
The original publication [1] contains a typographical typo in the Author's contributions section: "CS wrote the grant application." The correct sentence is: "CF coordinates the FemNAT-CD FP7 research project."
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- 2017
29. Community Violence Exposure and Conduct Problems in Children and Adolescents with Conduct Disorder and Healthy Controls
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Kersten, Linda, primary, Vriends, Noortje, additional, Steppan, Martin, additional, Raschle, Nora M., additional, Praetzlich, Martin, additional, Oldenhof, Helena, additional, Vermeiren, Robert, additional, Jansen, Lucres, additional, Ackermann, Katharina, additional, Bernhard, Anka, additional, Martinelli, Anne, additional, Gonzalez-Madruga, Karen, additional, Puzzo, Ignazio, additional, Wells, Amy, additional, Rogers, Jack C., additional, Clanton, Roberta, additional, Baker, Rosalind H., additional, Grisley, Liam, additional, Baumann, Sarah, additional, Gundlach, Malou, additional, Kohls, Gregor, additional, Gonzalez-Torres, Miguel A., additional, Sesma-Pardo, Eva, additional, Dochnal, Roberta, additional, Lazaratou, Helen, additional, Kalogerakis, Zacharias, additional, Bigorra Gualba, Aitana, additional, Smaragdi, Areti, additional, Siklósi, Réka, additional, Dikeos, Dimitris, additional, Hervás, Amaia, additional, Fernández-Rivas, Aranzazu, additional, De Brito, Stephane A., additional, Konrad, Kerstin, additional, Herpertz-Dahlmann, Beate, additional, Fairchild, Graeme, additional, Freitag, Christine M., additional, Popma, Arne, additional, Kieser, Meinhard, additional, and Stadler, Christina, additional
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- 2017
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30. Community violence exposure and conduct problems in children and adolescents with conduct disorder and healthy controls
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Alia-Klein, Nelly, Kersten, Linda, Vriends, Noortje, Steppan, Martin, Raschle, Nora Maria, Prätzlich, Martin, Oldenhof, Helena, Vermeiren, Robert, Jansen, Lucres, Ackermann, Katharina, Bernhard, Anka, Martinelli, Anne, Gonzalez-Madruga, Karen, Puzzo, Ignazio, Wells, Amy, Rogers, Jack C., Clanton, Roberta, Baker, Rosalind, Grisley, Liam, Baumann, Sarah, Gundlach, Malou, Kohls, Gregor, Gonzalez-Torres, Miguel A., Sesma-Pardo, Eva, Dochnal, Roberta, Lazaratou, Helen, Kalogerakis, Zacharias, Gualba, Aitana Bigorra, Smaragdi, Areti, Siklósi, Réka, Dikeos, Dimitris, Hervás, Amaia, Fernández-Rivas, Aranzazu, De Brito, Stéphane A., Konrad, Kerstin, Herpertz-Dahlmann, Beate, Fairchild, Graeme, Freitag, Christine M., Popma, Arne, Kieser, Meinhard, Stadler, Christina, Alia-Klein, Nelly, Kersten, Linda, Vriends, Noortje, Steppan, Martin, Raschle, Nora Maria, Prätzlich, Martin, Oldenhof, Helena, Vermeiren, Robert, Jansen, Lucres, Ackermann, Katharina, Bernhard, Anka, Martinelli, Anne, Gonzalez-Madruga, Karen, Puzzo, Ignazio, Wells, Amy, Rogers, Jack C., Clanton, Roberta, Baker, Rosalind, Grisley, Liam, Baumann, Sarah, Gundlach, Malou, Kohls, Gregor, Gonzalez-Torres, Miguel A., Sesma-Pardo, Eva, Dochnal, Roberta, Lazaratou, Helen, Kalogerakis, Zacharias, Gualba, Aitana Bigorra, Smaragdi, Areti, Siklósi, Réka, Dikeos, Dimitris, Hervás, Amaia, Fernández-Rivas, Aranzazu, De Brito, Stéphane A., Konrad, Kerstin, Herpertz-Dahlmann, Beate, Fairchild, Graeme, Freitag, Christine M., Popma, Arne, Kieser, Meinhard, and Stadler, Christina
- Abstract
Exposure to community violence through witnessing or being directly victimized has been associated with conduct problems in a range of studies. However, the relationship between community violence exposure (CVE) and conduct problems has never been studied separately in healthy individuals and individuals with conduct disorder (CD). Therefore, it is not clear whether the association between CVE and conduct problems is due to confounding factors, because those with high conduct problems also tend to live in more violent neighborhoods, i.e., an ecological fallacy. Hence, the aim of the present study was: (1) to investigate whether the association between recent CVE and current conduct problems holds true for healthy controls as well as adolescents with a diagnosis of CD; (2) to examine whether the association is stable in both groups when including effects of aggression subtypes (proactive/reactive aggression), age, gender, site and socioeconomic status (SES); and (3) to test whether proactive or reactive aggression mediate the link between CVE and conduct problems. Data from 1178 children and adolescents (62% female; 44% CD) aged between 9 years and 18 years from seven European countries were analyzed. Conduct problems were assessed using the Kiddie-Schedule of Affective Disorders and Schizophrenia diagnostic interview. Information about CVE and aggression subtypes was obtained using self-report questionnaires (Social and Health Assessment and Reactive-Proactive aggression Questionnaire (RPQ), respectively). The association between witnessing community violence and conduct problems was significant in both groups (adolescents with CD and healthy controls). The association was also stable after examining the mediating effects of aggression subtypes while including moderating effects of age, gender and SES and controlling for effects of site in both groups. There were no clear differences between the groups in the strength of the association between witnessing violence a
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- 2017
31. START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders : study protocol for a clusterrandomised controlled trial
- Author
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Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert Lee, Stadler, Christina, Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert Lee, and Stadler, Christina
- Abstract
Background: In Europe, the number of females exhibiting oppositional defiant disorder (ODD) and conduct disorder (CD) is growing. Many of these females live in youth welfare institutions. Consequently, there is a great need for evidence-based interventions within youth welfare settings. A recently developed approach targeting the specific needs of girls with ODD and CD in residential care is START NOW. The aim of this group-based behavioural skills training programme is to specifically enhance emotional regulation capacities to enable females with CD or ODD to appropriately deal with daily-life demands. It is intended to enhance psychosocial adjustment and well-being as well as reduce oppositional and aggressive behaviour. We present the study protocol (version 4.1; 10 February 2016) of the FemNAT-CD intervention trial titled "Group-Based Treatment of Adolescent Female Conduct Disorders: The Central Role of Emotion Regulation". Methods/design: The study is a prospective, confirmatory, cluster-randomised, parallel-group, multi-centre, randomised controlled trial with 128 institutionalised female adolescents who fulfil the diagnostic criteria of ODD and/or CD. Institutions/wards will be randomised either to provide the 12-week skills training as an add-on intervention or to provide treatment as usual. Once the first cycle is completed, each institution will run a second cycle with the opposite condition. Primary endpoints are the pre-post change in number of CD/ODD symptoms as assessed by a standardised, semi-structured psychiatric interview (Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children–Present and Lifetime, CD/ODD section) between baseline and the end of intervention, as well as between baseline and a 3-month follow-up point. Secondary objectives include pre-post change in CD/ODD-related outcome measures, most notably emotional regulation on a behavioural and neurobiological level after completion of START NOW compared with treatm
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- 2017
32. Erratum to : START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a clusterrandomised controlled trial
- Author
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Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert Lee, Stadler, Christina, Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert Lee, and Stadler, Christina
- Abstract
The original publication [doi:10.1186/s13063-016-1705-6] contains a typographical typo in the Author’s contributions section...
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- 2017
33. Additional file 1: of START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial
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Kersten, Linda, PräTzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine, Trestman, Robert, and Stadler, Christina
- Abstract
Example informed consent form used at the Basel site. (PDF 194 kb)
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- 2016
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34. Additional file 2: of START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial
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Kersten, Linda, PräTzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine, Trestman, Robert, and Stadler, Christina
- Abstract
SPIRIT 2013 Checklist. (DOC 121 kb)
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- 2016
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35. Developmental aspects of HPA-axis activity and Automomic Nervous System activity in relation to juvenile antisocial behaviour
- Author
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Popma, Arne, primary, Nauta-Jansen, Lucres, additional, and Oldenhof, Helena, additional
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- 2017
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36. START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial
- Author
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Kersten, Linda, primary, Prätzlich, Martin, additional, Mannstadt, Sandra, additional, Ackermann, Katharina, additional, Kohls, Gregor, additional, Oldenhof, Helena, additional, Saure, Daniel, additional, Krieger, Katrin, additional, Herpertz-Dahlmann, Beate, additional, Popma, Arne, additional, Freitag, Christine M., additional, Trestman, Robert L., additional, and Stadler, Christina, additional
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- 2016
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37. START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a cluster-randomised controlled trial
- Author
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Kersten, Linda, Prätzlich, Martin, Mannstadt, Sandra, Ackermann, Katharina, Kohls, Gregor, Oldenhof, Helena, Saure, Daniel, Krieger, Katrin, Herpertz-Dahlmann, Beate, Popma, Arne, Freitag, Christine M., Trestman, Robert L., and Stadler, Christina
- Subjects
3. Good health - Abstract
Trials 17(1), 568 (2016). doi:10.1186/s13063-016-1705-6, Published by BioMed Central, London
38. Community Violence Exposure and Conduct Problems in Children and Adolescents with Conduct Disorder and Healthy Controls
- Author
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Kersten, Linda, Vriends, Noortje, Steppan, Martin, Raschle, Nora M., Praetzlich, Martin, Oldenhof, Helena, Vermeiren, Robert, Jansen, Lucres, Ackermann, Katharina, Bernhard, Anka, Martinelli, Anne, Gonzalez-Madruga, Karen, Puzzo, Ignazio, Wells, Amy, Rogers, Jack C., Clanton, Roberta, Baker, Rosalind H., Grisley, Liam, Baumann, Sarah, Gundlach, Malou, Kohls, Gregor, Gonzalez-Torres, Miguel A., Sesma-Pardo, Eva, Dochnal, Roberta, Lazaratou, Helen, Kalogerakis, Zacharias, Bigorra Gualba, Aitana, Smaragdi, Areti, Siklósi, Réka, Dikeos, Dimitris, Hervás, Amaia, Fernández-Rivas, Aranzazu, De Brito, Stephane A., Konrad, Kerstin, Herpertz-Dahlmann, Beate, Fairchild, Graeme, Freitag, Christine M., Popma, Arne, Kieser, Meinhard, and Stadler, Christina
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16. Peace & justice ,3. Good health - Abstract
Frontiers in behavioral neuroscience 11, 219 (2017). doi:10.3389/fnbeh.2017.00219, Published by Frontiers Research Foundation, Lausanne
39. Community Violence Exposure and Conduct Problems in Children and Adolescents with Conduct Disorder and Healthy Controls
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Kersten, Linda, Vriends, Noortje, Steppan, Martin, Raschle, Nora M., Praetzlich, Martin, Oldenhof, Helena, Vermeiren, Robert, Jansen, Lucres, Ackermann, Katharina, Bernhard, Anka, Martinelli, Anne, Gonzalez-Madruga, Karen, Puzzo, Ignazio, Wells, Amy, Rogers, Jack C., Clanton, Roberta, Baker, Rosalind H., Grisley, Liam, Baumann, Sarah, Gundlach, Malou, Kohls, Gregor, Gonzalez-Torres, Miguel A., Sesma-Pardo, Eva, Dochnal, Roberta, Lazaratou, Helen, Kalogerakis, Zacharias, Bigorra Gualba, Aitana, Smaragdi, Areti, Siklósi, Réka, Dikeos, Dimitris, Hervás, Amaia, Fernández-Rivas, Aranzazu, De Brito, Stephane A., Konrad, Kerstin, Herpertz-Dahlmann, Beate, Fairchild, Graeme, Freitag, Christine M., Popma, Arne, Kieser, Meinhard, and Stadler, Christina
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16. Peace & justice ,3. Good health
40. Baseline autonomic nervous system activity in female children and adolescents with conduct disorder: Psychophysiological findings from the FemNAT-CD study
- Author
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Beate Herpertz-Dahlmann, Lucres M. C. Jansen, Arne Popma, Maider González de Artaza-Lavesa, Eco J. C. de Geus, Helen Lazaratou, Martin Steppan, Gregor Kohls, Helena Oldenhof, Martin Prätzlich, Anka Bernhard, Areti Smaragdi, Christine M. Freitag, Stephane A. De Brito, Réka Siklósi, Roberta Dochnal, Anne Martinelli, Sarah Baumann, Christina Stadler, Linda Kersten, Ignazio Puzzo, Meinhard Kieser, Katharina Ackermann, Malou Gundlach, Angeliki Konsta, Karen Gonzalez, Tisse van Nimwegen, Molly Batchelor, Amaia Hervás, Rosalind Baker, Dimitris Dikeos, Nora Maria Raschle, Kerstin Konrad, Graeme Fairchild, Roberta Clanton, Lynn Valérie Fehlbaum, Aranzazu Fernandez-Rivas, Silvina Guijarro, Jack C. Rogers, Iñaki Kerexeta-Lizeaga, ARD - Amsterdam Reproduction and Development, Biological Psychology, APH - Personalized Medicine, APH - Mental Health, Pediatric surgery, Amsterdam Reproduction & Development (AR&D), Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, University of Zurich, and Oldenhof, Helena
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Sociology and Political Science ,Social Psychology ,Physiology ,3202 Applied Psychology ,Conduct disorder ,SDG 3 - Good Health and Well-being ,3312 Sociology and Political Science ,Heart rate ,Sex differences ,medicine ,Heart rate variability ,Autonomic nervous system ,0501 psychology and cognitive sciences ,Applied Psychology ,3207 Social Psychology ,10093 Institute of Psychology ,business.industry ,Emotion regulation ,050901 criminology ,05 social sciences ,Sympathetic activity ,3308 Law ,medicine.disease ,Comorbidity ,Psychophysiology ,0509 other social sciences ,150 Psychology ,business ,Law ,10190 Jacobs Center for Productive Youth Development ,050104 developmental & child psychology - Abstract
Purpose: Autonomic nervous system (ANS) functioning has been widely studied in relation to antisocial behavior, such as Conduct Disorder (CD). However, research in females is scarce and findings are inconsistent. This study investigated baseline ANS activity in CD children and adolescents and tested for sex differences. Furthermore, subgroups of CD were investigated: +/‐ Limited Prosocial Emotions (LPE), +/‐ comorbid internalizing disorders (INT). Methods: Baseline ANS activity was measured by Heart Rate (HR), Heart Rate Variability (HRV; parasympathetic activity), Pre-Ejection Period (PEP; sympathetic activity), and Respiration Rate (RR). 659 females (296 CD, 363 controls) and 351 males (187 CD, 164 controls), aged 9–18 years participated. Results: Baseline HR, HRV and PEP did not differ between CD subjects and controls in both sexes. RR was higher in CD participants than controls amongst females, but not males. LPE was unrelated to ANS activity, whereas females with CD + INT presented lower HRV. Conclusions: These results suggest that baseline ANS activity is not a robust indicator for CD. However, deviant ANS activity – especially parasympathetic activity - was observed in CD females with internalizing comorbidity. The psychophysiological abnormalities observed in this subgroup are indicative of emotion regulation problems. Accordingly, this subgroup may require specific interventions.
- Published
- 2019
41. Neurobiological correlates of antisociality across adolescence and young adulthood: a multi-sample, multi-method study.
- Author
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Blankenstein NE, de Rooij M, van Ginkel J, Wilderjans TF, de Ruigh EL, Oldenhof HC, Zijlmans J, Jambroes T, Platje E, de Vries-Bouw M, Branje S, Meeus WHJ, Vermeiren RRJM, Popma A, and Jansen LMC
- Subjects
- Humans, Male, Adolescent, Young Adult, Adult, Female, Aggression psychology, Antisocial Personality Disorder, Testosterone, Emotions, Hydrocortisone, Conduct Disorder
- Abstract
Background: Antisociality across adolescence and young adulthood puts individuals at high risk of developing a variety of problems. Prior research has linked antisociality to autonomic nervous system and endocrinological functioning. However, there is large heterogeneity in antisocial behaviors, and these neurobiological measures are rarely studied conjointly, limited to small specific studies with narrow age ranges, and yield mixed findings due to the type of behavior examined., Methods: We harmonized data from 1489 participants (9-27 years, 67% male), from six heterogeneous samples. In the resulting dataset, we tested relations between distinct dimensions of antisociality and heart rate, pre-ejection period (PEP), respiratory sinus arrhythmia, respiration rate, skin conductance levels, testosterone, basal cortisol, and the cortisol awakening response (CAR), and test the role of age throughout adolescence and young adulthood., Results: Three dimensions of antisociality were uncovered: 'callous-unemotional (CU)/manipulative traits', 'intentional aggression/conduct', and 'reactivity/impulsivity/irritability'. Shorter PEPs and higher testosterone were related to CU/manipulative traits, and a higher CAR is related to both CU/manipulative traits and intentional aggression/conduct. These effects were stable across age., Conclusions: Across a heterogeneous sample and consistent across development, the CAR may be a valuable measure to link to CU/manipulative traits and intentional aggression, while sympathetic arousal and testosterone are additionally valuable to understand CU/manipulative traits. Together, these findings deepen our understanding of the fundamental mechanisms underlying different components of antisociality. Finally, we illustrate the potential of using current statistical techniques for combining multiple datasets to draw robust conclusions about biobehavioral associations.
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- 2023
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42. Psychophysiological responses to sadness in girls and boys with conduct disorder.
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Oldenhof H, Jansen L, Ackermann K, Baker R, Batchelor M, Baumann S, Bernhard A, Clanton R, Dochnal R, Fehlbaum LV, Fernandez-Rivas A, Goergen S, Gonzalez de Artaza-Lavesa M, Gonzalez-Madruga K, Gonzalez-Torres MA, Gundlach M, Lotte van der Hoeven M, Kalogerakis Z, Kapornai K, Kieser M, Konsta A, Martinelli A, Pauli R, Rogers J, Smaragdi A, Sesma-Pardo E, Siklósi R, Steppan M, Tsiakoulia F, Vermeiren R, Vriends N, Werner M, Herpertz-Dahlmann B, Kohls G, De Brito S, Konrad K, Stadler C, Fairchild G, Freitag CM, and Popma A
- Subjects
- Adolescent, Antisocial Personality Disorder, Emotions physiology, Humans, Sadness, Conduct Disorder, Respiratory Sinus Arrhythmia physiology
- Abstract
Reduced responsiveness to emotions is hypothesized to contribute to the development of conduct disorder (CD) in children and adolescents. Accordingly, blunted psychophysiological responses to emotions have been observed in boys with CD, but this has never been tested in girls. Therefore, this study compared psychophysiological responses to sadness in girls and boys with and without CD, and different clinical phenotypes of CD: with versus without limited prosocial emotions (LPE), and with versus without comorbid internalizing disorders (INT). Nine-hundred and 27 girls (427 CD, 500 controls) and 519 boys (266 CD, 253 controls) aged 9-18 years participated. Psychophysiological responses were measured while participants watched two validated sad film clips, specifically: heart rate (HR), respiratory sinus arrhythmia (RSA; indexing parasympathetic activity), preejection period (PEP; indexing sympathetic activity). Girls and boys with CD showed larger HR responses to sadness than controls. This effect was rendered nonsignificant, however, after controlling for covariates. We observed aberrant RSA responses to sadness in CD compared with controls. Similarly, we found a significant positive association between RSA responsivity and antisocial behavior when assessed dimensionally. The effects were very small, though. Results were similar for boys and girls. We found no evidence for emotional underresponsiveness in CD in the largest psychophysiological study to date in this field. More research is needed to explore whether this is specific to sadness or generalizes to other emotions. Furthermore, we recommend that studies on emotion processing in CD assess different physiological measures to help disentangle CD-related effects on sympathetic and parasympathetic activity. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
- Published
- 2022
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43. Positive and negative parenting in conduct disorder with high versus low levels of callous-unemotional traits.
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Pauli R, Tino P, Rogers JC, Baker R, Clanton R, Birch P, Brown A, Daniel G, Ferreira L, Grisley L, Kohls G, Baumann S, Bernhard A, Martinelli A, Ackermann K, Lazaratou H, Tsiakoulia F, Bali P, Oldenhof H, Jansen L, Smaragdi A, Gonzalez-Madruga K, Gonzalez-Torres MA, Gonzalez de Artaza-Lavesa M, Steppan M, Vriends N, Bigorra A, Siklosi R, Ghosh S, Bunte K, Dochnal R, Hervas A, Stadler C, Fernandez-Rivas A, Fairchild G, Popma A, Dikeos D, Konrad K, Herpertz-Dahlmann B, Freitag CM, Rotshtein P, and De Brito SA
- Subjects
- Adolescent, Child, Child, Preschool, Emotions, Empathy, Humans, Parenting, Conduct Disorder
- Abstract
Less is known about the relationship between conduct disorder (CD), callous-unemotional (CU) traits, and positive and negative parenting in youth compared to early childhood. We combined traditional univariate analyses with a novel machine learning classifier (Angle-based Generalized Matrix Learning Vector Quantization) to classify youth (N = 756; 9-18 years) into typically developing (TD) or CD groups with or without elevated CU traits (CD/HCU, CD/LCU, respectively) using youth- and parent-reports of parenting behavior. At the group level, both CD/HCU and CD/LCU were associated with high negative and low positive parenting relative to TD. However, only positive parenting differed between the CD/HCU and CD/LCU groups. In classification analyses, performance was best when distinguishing CD/HCU from TD groups and poorest when distinguishing CD/HCU from CD/LCU groups. Positive and negative parenting were both relevant when distinguishing CD/HCU from TD, negative parenting was most relevant when distinguishing between CD/LCU and TD, and positive parenting was most relevant when distinguishing CD/HCU from CD/LCU groups. These findings suggest that while positive parenting distinguishes between CD/HCU and CD/LCU, negative parenting is associated with both CD subtypes. These results highlight the importance of considering multiple parenting behaviors in CD with varying levels of CU traits in late childhood/adolescence.
- Published
- 2021
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44. Erratum to: START NOW - a comprehensive skills training programme for female adolescents with oppositional defiant and conduct disorders: study protocol for a clusterrandomised controlled trial.
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Kersten L, Prätzlich M, Mannstadt S, Ackermann K, Kohls G, Oldenhof H, Saure D, Krieger K, Herpertz-Dahlmann B, Popma A, Freitag CM, Trestman RL, and Stadler C
- Published
- 2017
- Full Text
- View/download PDF
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