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A study conducted at the University of Southern Denmark explored the feasibility and acceptability of a virtual diagnostic process for common sleep disorders. The research involved digital questionnaire administration, neurophysiological diagnostic studies, and virtual consultations with a sleep specialist. While most participants found the virtual diagnostic process meaningful, they emphasized the importance of personal contact, either through telephone or video, to address concerns. The study concluded that the virtual diagnostic process represents the outer limit of electronic data collection in virtual diagnostic procedures. [Extracted from the article]

A recent study from the University of Southern Denmark explores the use of Raman spectroscopy in monitoring biopharmaceutical production processes, specifically in Saccharomyces cerevisiae fermentations. The research highlights the potential of Raman spectroscopy for real-time monitoring and control of complex microbial fermentations, improving the efficiency and quality of biopharmaceutical production. By utilizing advanced chemometric modeling and variable importance in projection (VIP), the study demonstrates accurate predictions of protein concentration and key process parameters essential for optimizing biopharmaceutical fermentation processes. This research provides valuable insights into enhancing biopharmaceutical production through innovative analytical methods. [Extracted from the article]

A recent study from the University of Southern Denmark explores the use of machine learning in scheduling and rescheduling elective and emergency patients in operating theatres. The research proposes an integrated model that combines various concepts to improve the efficiency of operating rooms. By utilizing machine learning models and optimization algorithms, the study aims to enhance the scheduling process and ensure timely care for emergency patients. The results suggest that the proposed approach has a positive impact on operating room schedules, highlighting the potential benefits of integrating machine learning in healthcare operations. [Extracted from the article]

A study conducted at Odense University Hospital in Denmark compared the immunological effects of post-operative epidural analgesia versus oral opioids in patients undergoing video-assisted thoracoscopic surgery (VATS) lobectomy for cancer. The research found no significant differences in plasma concentrations of interleukin and interferon between the two pain management methods, and there was no variance in survival rates after a two-year follow-up. The study was funded by the Danish Cancer Society and other organizations, and the findings were published in the Danish Medical Journal. [Extracted from the article]

A recent study conducted in Denmark by the University of Southern Denmark examined the support provided to caregivers of individuals diagnosed with various life-threatening diseases, including dementia. The research found that identification of caregivers and support initiatives varied across different diagnoses and healthcare settings, with dementia care showing higher rates of caregiver identification and support. The study highlighted the need for disease-specific clinical guidelines to ensure adequate support for caregivers, emphasizing the importance of focusing on vulnerable caregivers in clinical practice. Future research should explore how caregivers' needs can be met across different diagnoses and healthcare settings. [Extracted from the article]

Researchers from the University of Southern Denmark conducted a study on Adjustment Disorders, focusing on work-related stress disorders in Denmark. They translated and validated the International Adjustment Disorder Questionnaire (IADQ) among social educators, finding a two-factor model that reflects preoccupation and failure to adapt. The study suggests that further research should explore the structure of adjustment disorder in different working populations. This research was supported by Region Southern Denmark and has been peer-reviewed. [Extracted from the article]

A recent study conducted by the University of Southern Denmark examined the development and persistence of multiple physical symptoms (MPS) over a decade, focusing on the associations with sociodemographics and coping strategies. The research found that individuals who developed or had persistence of MPS were more likely to be female, have lower educational levels, be immigrants, redeem antidepressants, and exhibit specific coping strategies. The study suggests that targeting maladaptive coping strategies, especially in high-risk groups, through psychotherapy may be crucial in preventing and managing MPS. [Extracted from the article]

A study conducted by the University of Southern Denmark examined the risk of neurodevelopmental or behavioral disorders in children conceived through assisted reproductive technologies compared to those conceived without such methods. The research found that children conceived through assisted reproductive technologies had a slightly higher likelihood of being prescribed neurodevelopmental or behavioral medication. However, the study also noted that factors such as birth weight and preterm birth mediated this association, and overall, there was little evidence of an increased risk of such disorders in children conceived using assisted reproductive technologies. [Extracted from the article]

A recent study conducted at Odense University Hospital in Denmark focused on the prevalence of concerns about falling (CaF) in individuals with knee or hip osteoarthritis. The study, which included 7442 patients, found that moderate CaF was observed in 48.1% of participants, with higher levels of CaF in older individuals and females. The research highlighted the association between CaF, pain, function, and psychological factors, emphasizing the need to integrate CaF assessments and interventions into osteoarthritis management in primary care. [Extracted from the article]

Researchers at the University of Southern Denmark conducted an integrative review to explore how nurses can help alleviate protective buffering between adult cancer patients and their adult family caregivers. The study included 22 articles and focused on communication in oncology, hematology, and multiple settings. The research concluded that nurses play a crucial role in facilitating communication between adults with cancer and their family caregivers. For more information, the full study can be found in the Journal of Family Nursing. [Extracted from the article]

A recent study conducted by the Danish Institute for Advanced Study in Odense, Denmark, explores the complexities of interpersonal physiology during rupture and repair episodes in the treatment of Borderline Personality Disorder. The research utilizes a multimethod approach, including patient self-reporting questionnaires, observation-based ratings of sessions, quantitative analysis of heart rate variability, and qualitative multimodal interaction analysis. The findings suggest that patterns of heart rate synchrony between patient and therapist correspond to key therapeutic alliance processes, with physiological arousal underlying important alliance processes. The study emphasizes the importance of applying multimethod approaches when studying rupture and repair processes in psychotherapy. [Extracted from the article]

A recent study conducted at Odense University Hospital in Denmark examined the long-term stability of five atypical antipsychotic drugs (risperidone, paliperidone, clozapine, quetiapine, and olanzapine) and the antidepressant mirtazapine in serum samples. The research found that these drugs remained stable for varying durations at different storage temperatures and during freeze-thaw cycles. The study recommended storing samples at -80 degrees Celsius for extended periods and at -20 degrees Celsius for shorter durations. This peer-reviewed research provides valuable insights for the analysis and storage of antipsychotic and antidepressant medications. [Extracted from the article]

Researchers from Odense University Hospital conducted a nationwide cohort study on the risk and epidemiology of periprosthetic knee fractures (PPKFs) after primary total knee arthroplasty (TKA). The study included 120,642 standard primary TKA patients, with 1,659 PPKFs identified over a span of 25 years. Significant risk factors for PPKFs included ipsilateral hip arthroplasty, being female, osteoporosis, advanced age, uncemented TKA, and higher Charlson Comorbidity Index scores. The research concluded that higher risks were observed in non-osteoarthritis patients and those with a higher level of TKA constraint. [Extracted from the article]

A recent study conducted at Odense University Hospital in Denmark explored the presence and attributes of health professionals (HPs) in connecting with parents of children with cancer. The study found that HPs play a crucial role in providing support to families, with many developing close and genuine connections with parents based on commitment, communication, and clinical competencies. However, barriers such as work changes, busyness, and poor communication were also identified. The research emphasizes the importance of understanding and improving professional relationships to better support families facing childhood cancer. [Extracted from the article]

A recent study conducted at the University of Southern Denmark explored the impact of hypoglycemia on the quality of life among adults with type 1 diabetes. The research found that severe and self-treated hypoglycemia, as well as impaired awareness, negatively affected various aspects of quality of life, such as leisure activities, emotional well-being, and work/studies. Psychological factors were identified as having a greater influence on quality of life than hypoglycemia frequency and awareness. This peer-reviewed study sheds light on the complex relationship between hypoglycemia and quality of life in individuals with type 1 diabetes. [Extracted from the article]

A recent systematic review and meta-analysis conducted by researchers at the University of Southern Denmark explored nutrition interventions for preventing weight loss in patients with head and neck cancer undergoing radiation or chemoradiation therapy. The review included 27 studies and found that oral nutritional supplements (ONS) combined with weekly individualized nutrition counseling (INC) had a beneficial effect on weight change and nutritional status. However, the meta-analysis showed a non-significant effect of ONS alone and no overall effect of INC. The researchers concluded that further research is needed to enhance patient compliance and involvement in these interventions. [Extracted from the article]

A recent study conducted by the University of Southern Denmark examined the correlation of anogenital distance (AGD) from infancy to 9 years of age in boys and girls. AGD is considered a marker for prenatal androgen action and has been associated with various health conditions. The study found that AGD in boys correlated significantly from infancy to 9 years, suggesting that AGD in infancy could be a non-invasive marker of later reproductive health. However, correlations were weaker in girls, potentially due to less precise measurements and greater variability. Further research is needed to evaluate the long-term tracking of AGD and its potential as an early marker of adult reproductive health. [Extracted from the article]

A recent study conducted by the University of Southern Denmark aimed to evaluate the accuracy of PET/MRI in diagnosing inflammatory bowel disease (IBD) in pediatric patients. The study included 43 patients aged 8-17 years who underwent a PET/MRI scan and subsequent ileocolonoscopy. The results showed that PET/MRI had a sensitivity of 0.83 and a specificity of 0.57 in detecting inflammation in the terminal ileum and colon. The researchers concluded that while PET/MRI may still be valuable in selected cases, it was not superior to either modality alone. [Extracted from the article]

A recent study conducted in Odense, Denmark, examined the relationship between health literacy, smoking status, and healthcare seeking behavior among individuals with lung cancer symptoms. The study found that individuals who currently smoke were less likely to seek medical attention, while those who felt understood and supported were more likely to seek medical help. The researchers concluded that interventions targeting individuals at risk of delaying healthcare seeking are necessary to improve timely diagnosis and treatment. This study highlights the importance of health literacy in promoting timely healthcare seeking for lung cancer symptoms. [Extracted from the article]

A recent report from the University of Southern Denmark highlights the limitations of current international tourism statistics and proposes a new data-driven approach using big data from Tripadvisor. This approach provides more detailed and timely information on tourism flows and attractions in a country. The researchers applied this method to analyze travel patterns in selected European destinations during and after the COVID-19 pandemic. The study concludes that this approach opens up new possibilities for research in tourism economics and cultural economics. [Extracted from the article]

Researchers at the University of Southern Denmark have conducted a study on sensing technologies for guidance during needle-based interventions. The study highlights the challenges of accurately targeting deep tissue structures during needle insertion and reviews recent developments in sensing techniques to aid insertion accuracy. The research concludes that advancements in machine learning integration, miniaturization, and enhanced multimodal sensing capabilities can improve procedural outcomes and expand application domains. The study was supported by Innovation Fund Denmark and has been peer-reviewed. [Extracted from the article]

Researchers from Odense University Hospital in Denmark have conducted a study to determine if polymerase chain reaction (PCR) can accurately detect bacteria in the peritoneal fluid of patients with acute appendicitis. The study included 102 patients who underwent laparoscopic surgery for acute appendicitis, and samples were collected for both conventional culture and PCR using the BioFire Blood Culture Identification 2 Panel. The results showed that PCR had a 71.4% concordance with conventional culture in detecting bacteria. The study suggests that PCR has the potential to guide postoperative antibiotic treatment in patients with acute appendicitis. [Extracted from the article]

A recent study conducted by the University of Southern Denmark explores the dynamics of therapeutic conversations between parents and therapists at a pain clinic for children and young people with recurrent or chronic pain. The research examines how the meaning of symptoms and the positioning of individuals are constructed through dialogue, particularly focusing on the role of parents in negotiating moral assessments assigned to their children. The study suggests that these conversations involve not only the sufferers' moral positions but also those of their parents. The research emphasizes the importance of understanding the complex dynamics of these interactions in order to establish and negotiate the meaning of symptoms. [Extracted from the article]

The article reports on a study conducted at Odense University Hospital that examines the use of liver stiffness measurement (LSM) to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease (ALD). Topics discussed include the use of transient elastography for prognostication, the accuracy of LSM in predicting patient outcomes, and the role of LSM changes in identifying patients at higher risk of adverse events.

A study conducted by UCL University College in Odense, Denmark, examined six recommended measures for assessing violence exposure in children and adolescents. The study found that there was a lack of consensus among these measures, with only a modest overlap in items. This lack of agreement hinders research and makes it difficult to compare studies. The researchers concluded that the absence of consensus also delays effective political initiatives and prevents the establishment of solid knowledge about the prevalence of violence against children. [Extracted from the article]

A recent report from the University of Southern Denmark challenges the precautionary measures recommended by the European Medicines Agency (EMA) and the Medicines and Healthcare products Regulatory Agency (MHRA) regarding the use of valproate in men. The EMA and MHRA had suggested that there may be a risk of neurodevelopmental disorders in children born to men treated with valproate, but the researchers argue that the scientific data does not convincingly support this claim. The study suggests that the regulatory measures may have been premature and that further research is needed to substantiate these recommendations. [Extracted from the article]

A recent study conducted at the University of Southern Denmark has provided new insights into the preparation of nano- and microsuspensions for long-acting injectables of antipsychotic agents. The study focused on the deformation properties of three model compounds (cinnarizine, haloperidol, and indomethacin) and their particle size profiles when prepared under the same manufacturing conditions. The researchers found that cinnarizine had brittle properties, haloperidol had plastic properties, and indomethacin had elastic properties. The study also revealed that different stabilizers and concentrations were needed to obtain smaller particle sizes for each compound. Short-term stability studies showed that the physical stability of the particles varied among the compounds. This research has been peer-reviewed and provides valuable information for the development of antipsychotic drug formulations. [Extracted from the article]

A new study from the University of Southern Denmark examines the impact of not implementing a strict lockdown in the Bergamo province during the first wave of the COVID-19 pandemic. The researchers estimate that about two-thirds of the reported deaths in the area could have been avoided if a strict lockdown had been implemented. The study uses the synthetic control method to assess the causal effect of this policy decision on daily excess mortality. The research concludes that the effectiveness of lockdown measures is still a topic of debate and provides a way to empirically assess the credibility of assumptions in this context. [Extracted from the article]

A recent study conducted at the University of Southern Denmark explored the molecular interactions between the crystalline and amorphous forms of telmisartan, an angiotensin II receptor antagonist used in cardiovascular therapy. The researchers used spectroscopies and computational simulations to compare the behavior of the two forms. They found that the amorphous form had a weaker and less extensive hydrogen bonding network compared to the crystalline form. This research provides insights into the differences between the two forms of telmisartan and their potential implications for pharmaceutical development. [Extracted from the article]

New research from the University of Southern Denmark suggests that low levels of vitamin D during pregnancy may be associated with symptoms of attention-deficit hyperactivity disorder (ADHD) in children at age 5. The study analyzed data from 944 mother-child pairs and found that lower levels of serum 25-hydroxyvitamin D in cord blood and early pregnancy were linked to higher ADHD symptom scores in children. The findings suggest a potential protective effect of vitamin D on ADHD traits in preschool-aged children. Further research is needed to better understand the relationship between vitamin D and ADHD. [Extracted from the article]

A systematic review conducted by researchers at the University of Southern Denmark explores the use of artificial intelligence (AI) in detecting cervical pre-cancerous lesions and cancer. The study analyzes various AI technologies applied to different diagnostic methods, such as Pap Smear tests, colposcopy, and imaging modalities. The review finds that deep learning models are effective for imaging techniques, while machine learning-based models are suitable for sociodemographic data. The researchers emphasize the need for diverse datasets, model explainability, and data privacy concerns in the development and deployment of AI models for cervical cancer detection. [Extracted from the article]

A systematic review conducted by the University of Southern Denmark examined the use of psychotropic drugs among children and adolescents in the Nordic countries. The review found significant variations in psychotropic drug use among different Nordic countries, despite their similar populations and healthcare systems. The use of psychotropic drugs, such as antidepressants and psychostimulants, varied greatly between countries. The study suggests that further investigation is needed to address these national variations and improve rational pharmacotherapy for youths with psychiatric disorders. [Extracted from the article]

The article reports on a mixed-methods review from University College London (UCL) regarding work interventions for individuals with dementia. Topics discussed include the challenges faced by people with dementia in the workplace, recommendations for effective work interventions, and the key elements for successful implementation, such as a person-centered and dynamic approach.

A recent study conducted by the University of Southern Denmark examined the associations between autism spectrum disorder (ASD) and physical diseases (PD) in a nationwide cohort. The study found that individuals with ASD had a higher risk of developing a multitude of physical diseases, particularly in infancy and childhood. The risks were observed for both sexes, but were stronger among females. The study concluded that individuals with ASD are at an increased risk for various physical comorbidities. [Extracted from the article]

A recent report from Odense University Hospital in Denmark explores the experiences and needs of adolescents and young adults with epilepsy as they transition from pediatric to adult hospital care. The study used a systematic review and meta-synthesis of qualitative studies to examine the holistic perspective of these individuals during the transition. The findings reveal that the transition experience for those with epilepsy is more than just a change in clinics, but rather a complex interplay of developmental, health-illness, situational, and organizational transition issues. The study emphasizes the importance of creating an inclusive and supportive environment to help these individuals develop responsibility, independence, and confidence as they navigate the transition. [Extracted from the article]

A study conducted at Odense University Hospital in Denmark examined the association between paternal diabetes mellitus (DM) and successful pregnancy in couples undergoing reproductive treatment. The study included 101,875 embryo transfers and found that paternal DM was not significantly associated with a decreased chance of biochemical pregnancy, clinical pregnancy, or live birth. The research suggests that while maternal factors have been extensively studied, the influence of paternal factors on pregnancy outcomes is not well understood. The study was supported by Merck and has been peer-reviewed. [Extracted from the article]

A recent report from the University of Southern Denmark discusses the rare neurodevelopmental syndrome known as KBG syndrome (KBGS). The study aimed to understand the clinical features of KBGS in adults by collecting physician-reported data and conducting a literature review. The research identified 36 adults with KBGS, highlighting symptoms such as intellectual disability, motor difficulties, psychiatric and behavioral comorbidities, seizures, and ophthalmological conditions. The study sheds light on the long-term outcomes and various aspects of the lives of adults with KBGS. [Extracted from the article]