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1. Anticholinesterase, Antioxidative and Neuroprotective Effects of Hydroethanolic Extracts of Guiera Senegalensis J. F. Gmel. Leaves on Scopolamine Induced Alzheimer's Disease in Wistar Rat Models.

Author

Harquin Simplice, Foyet, Damo Kamda, Jorelle Linda, Desire Guedang, Nyayi Simon, Ciobica, Alin, Kamal, Fatima Zahra, Woumitna Camdi, Guillaume, Bouvourne, Parfait, Rebe Nouma, Roland, Blondelle Kenko Djoumessie, Lea, Novae, Bogdan, Calin, Gabriela, Iordache, Alin, Ionescu, Cătălina, and Kamleu Nkwingwa, Balbine

Subjects
CHOLINESTERASE inhibitors, SCOPOLAMINE, ALZHEIMER'S disease, OXIDATIVE stress, NEUROINFLAMMATION, NEURODEGENERATION
Abstract

The article focuses on evaluating the anticholinesterase, antioxidative, and neuroprotective effects of hydroethanolic extracts of Guiera senegalensis leaves on scopolamine-induced Alzheimer's disease in Wistar rat models. Topics include the improvement of memory and learning through behavioral tests, modulation of cholinergic and oxidative stress pathways, and the reduction of neuroinflammatory and neurodegenerative markers.

Published
2024
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