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Anticholinesterase, Antioxidative and Neuroprotective Effects of Hydroethanolic Extracts of Guiera Senegalensis J. F. Gmel. Leaves on Scopolamine Induced Alzheimer's Disease in Wistar Rat Models.

Authors :
Harquin Simplice, Foyet
Damo Kamda, Jorelle Linda
Desire Guedang, Nyayi Simon
Ciobica, Alin
Kamal, Fatima Zahra
Woumitna Camdi, Guillaume
Bouvourne, Parfait
Rebe Nouma, Roland
Blondelle Kenko Djoumessie, Lea
Novae, Bogdan
Calin, Gabriela
Iordache, Alin
Ionescu, Cătălina
Kamleu Nkwingwa, Balbine
Source :
Jundishapur Journal of Natural Pharmaceutical Products; Nov2024, Vol. 19 Issue 4, p1-16, 16p
Publication Year :
2024

Abstract

The article focuses on evaluating the anticholinesterase, antioxidative, and neuroprotective effects of hydroethanolic extracts of Guiera senegalensis leaves on scopolamine-induced Alzheimer's disease in Wistar rat models. Topics include the improvement of memory and learning through behavioral tests, modulation of cholinergic and oxidative stress pathways, and the reduction of neuroinflammatory and neurodegenerative markers.

Details

Language :
English
ISSN :
17357780
Volume :
19
Issue :
4
Database :
Complementary Index
Journal :
Jundishapur Journal of Natural Pharmaceutical Products
Publication Type :
Academic Journal
Accession number :
181592733
Full Text :
https://doi.org/10.5812/jjnpp-147530