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1. Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies

Author

Twait, Emma L., Kamarioti, Maria, Verberk, Inge M.W., Teunissen, Charlotte E., Nooyens, Astrid C.J., Monique Verschuren, W.M., Visser, Pieter Jelle, Huisman, Martijn, Kok, Almar A.L., Eline Slagboom, P., Beekman, Marian, Vojinovic, Dina, Lakenberg, Nico, Arfan Ikram, M., Schuurmans, Isabel K., Wolters, Frank J., Moonen, Justine E.F., Gerritsen, Lotte, van der Flier, Wiesje M., and Geerlings, Mirjam I.

Published
2024
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2. Biomarkers of endothelial dysfunction and cognition: A two‐step IPD meta‐analysis.

Author

Beran, Magdalena, Jansen, Willemijn J., Oomens, Julie E., Moonen, Justine E. F., Slagboom, P. Eline, Huisman, Martijn, Kok, Almar A. L., Nooyens, Astrid C. J., Verschuren, Wilhelmina Maria Monique, Stehouwer, Coen D. A., Schalkwijk, Casper, Köhler, Sebastian, Beekman, Marian, Slagboom, Pieternella Eline, Wolters, Frank J., Ikram, M. Arfan, Vallerga, Costanza L., van Meurs, Joyce B. J., Ghanbari, Mohsen, and Vonk, Jet M. J.

Published
2024
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5. Depressive Symptoms and Plasma Markers of Alzheimer's Disease and Neurodegeneration: A Coordinated Meta-Analysis of 8 Cohort Studies

Author

Cardiovasculaire Epi Team 5, Cardiovasculaire Epi Team 7a, Cardiometabolic Health, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Brain, Twait, Emma L, Kamarioti, Maria, Verberk, Inge M W, Teunissen, Charlotte E, Nooyens, Astrid C J, Monique Verschuren, W M, Visser, Pieter Jelle, Huisman, Martijn, Kok, Almar A L, Eline Slagboom, P, Beekman, Marian, Vojinovic, Dina, Lakenberg, Nico, Arfan Ikram, M, Schuurmans, Isabel K, Wolters, Frank J, Moonen, Justine E F, Gerritsen, Lotte, van der Flier, Wiesje M, Geerlings, Mirjam I, NCDC Consortium, Cardiovasculaire Epi Team 5, Cardiovasculaire Epi Team 7a, Cardiometabolic Health, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Brain, Twait, Emma L, Kamarioti, Maria, Verberk, Inge M W, Teunissen, Charlotte E, Nooyens, Astrid C J, Monique Verschuren, W M, Visser, Pieter Jelle, Huisman, Martijn, Kok, Almar A L, Eline Slagboom, P, Beekman, Marian, Vojinovic, Dina, Lakenberg, Nico, Arfan Ikram, M, Schuurmans, Isabel K, Wolters, Frank J, Moonen, Justine E F, Gerritsen, Lotte, van der Flier, Wiesje M, Geerlings, Mirjam I, and NCDC Consortium

Published
2024

6. Alzheimer’s disease plasma markers and depressive symptoms: an IPD meta‐analysis

Author

Twait, Emma L., primary, Kamarioti, Maria, additional, Verberk, Inge M.W., additional, Teunissen, Charlotte E., additional, Nooyens, Astrid C.J., additional, Verschuren, Monique WM, additional, Visser, Pieter Jelle, additional, Huisman, Martijn, additional, Kok, Almar A.L., additional, Slagboom, P. Eline, additional, Beekman, Marian, additional, Ikram, M. Arfan, additional, Schuurmans, Isabel K, additional, Wolters, Frank J., additional, Moonen, Justine E., additional, Gerritsen, Lotte, additional, van der Flier, Wiesje M., additional, and Geerlings, Mirjam I., additional

Published
2023
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10. Sex Differences in Cognitive Functioning with Aging in the Netherlands

Author

Public Health Practice, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C.J., Wijnhoven, Hanneke A.H., Schaap, Laura S., Sialino, Lena D., Kok, Almar A.L., Visser, Marjolein, Verschuren, W. M.Monique, Picavet, H. Susan J., Van Oostrom, Sandra H., Public Health Practice, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C.J., Wijnhoven, Hanneke A.H., Schaap, Laura S., Sialino, Lena D., Kok, Almar A.L., Visser, Marjolein, Verschuren, W. M.Monique, Picavet, H. Susan J., and Van Oostrom, Sandra H.

Published
2022

14. List of Contributors

Author

Abbatecola, Angela Marie, primary, Abe, Koji, additional, Abisambra, Jose F., additional, Ahmad, Aliya, additional, Alaei, Hojjatollah, additional, Alagiakrishnan, Kannayiram, additional, Aliev, Gjumrakch, additional, Allegri, Ricardo Francisco, additional, Almeida, Osvaldo P., additional, Álvarez-Cervera, Fernando J., additional, Alwi, Nor Amalina Ahmad, additional, Ames, David, additional, Anderson-Mooney, Amelia Jane, additional, Andrade, José Paulo, additional, Anglés, Neus, additional, Armstrong, R.A., additional, Assunção, Marco, additional, Atteia, Hebatallah Husseini, additional, Avila, Marco Fidel, additional, Bair, Ming-Jong, additional, Barbagallo, Mario, additional, Barberger-Gateau, Pascale, additional, Barbieri, Michelangela, additional, Barreto, George E., additional, Bata-García, José L., additional, Begum, Monirun, additional, Bellia, Francesco, additional, Belvedere, Mario, additional, Bennett, Louise E., additional, Białecka, Monika, additional, Bird, Michael, additional, Blundo, Carlo, additional, Boccardi, Virginia, additional, Bolea, Irene, additional, Bosco, Domenico, additional, Brouwer-Brolsma, Elske M., additional, Brust, John C.M., additional, Buffa, Roberto, additional, Bunner, Kendra D., additional, Burri, Lena, additional, Cabezas, Ricardo, additional, Camina, María Alicia, additional, Campbell, Tessa N., additional, Cano, Lourdes Rexach, additional, Chen, Huan-Lin, additional, Chen, Jianmin, additional, Cheung, David Wing-Shing, additional, Choy, Francis Y.M., additional, Chua, J., additional, Colica, Carmen, additional, Corcia, Philippe, additional, Craft, Suzanne, additional, Cristiano, Dario, additional, Cusimano, Michael D., additional, Dalton, Kate, additional, Davidson, Terry L., additional, De Bartolo, Matteo, additional, de Bem, Andreza Fabro, additional, de Castro, Isac, additional, de Groot, Lisette C.P.G.M., additional, de la Cruz Marcos, Sandra, additional, de Oliveira, Jade, additional, del Balzo, Valeria, additional, Deguchi, Kentaro, additional, Deguchi, Shoko, additional, Deth, Richard, additional, Dominguez, Ligia J., additional, Donini, Lorenzo M., additional, Doruk, Huseyin, additional, Dziewas, Rainer, additional, Díes, Rafael Carles, additional, El-Bachá, Ramon Santos, additional, El-Swefy, Sahar Elsayed, additional, Enciso, Laura Carreño, additional, Ermio, Caterina, additional, Escribano, Begoña M., additional, Estrada-Sánchez, Ana María, additional, Etgen, Thorleif, additional, Farina, Marcelo, additional, Fava, Antonietta, additional, Feart, Catherine, additional, Feng, Lei, additional, Fernández-Fernández, Laura, additional, Ferreira, Danilio Alvear Sampaio, additional, Fiala, Milan, additional, Fialdini, Renata Caruso, additional, Fisher, Cheryl, additional, Galimberti, Daniela, additional, Galvin, James E., additional, Gelber, Rebecca P., additional, Gerace, Carmela, additional, Giannakopoulos, Panteleimon, additional, Giannopoulos, Phillip F., additional, Giridharan, Vijayasree V., additional, Giusti, Anna Maria, additional, Gonzalez, Janneth, additional, Góngora-Alfaro, José L., additional, Gordon, Paul H., additional, Greiwe, Jeffrey S., additional, Grima, Natalie A., additional, Guedes, Rubem, additional, Gupta, Susham, additional, Gyengesi, Erika, additional, Haller, Sven, additional, Hanson, Angela J., additional, Harvey, Jenni, additional, Hassan, Ossama Morsi, additional, Henderson, Samuel T., additional, Herrup, Karl, additional, Hickey, M.A., additional, Hoerr, Robert, additional, Hou, Xiaoli, additional, Huang, Chengyu, additional, Hügel, Helmut M., additional, Hwang, Sam-Long, additional, Ikeda, Yoshio, additional, Irie, Kazuhiro, additional, Jack, Alexandria, additional, Jackson, Neale, additional, Jackson, Richard L., additional, Jannise, Brittany, additional, Jiang, Yugang, additional, Johnson, C.Shanthi, additional, Jolliff, James S., additional, Jové, Mariona, additional, Kam, Jonathan S., additional, Kanoski, Scott E., additional, Khan, Khurshid, additional, Kimura, Takemi, additional, Kitagishi, Yasuko, additional, Konishi, Tetsuya, additional, Kovacs, Gabor G., additional, Krause, Debra, additional, Kua, Ee-Heok, additional, Kurata, Tomoko, additional, Kurian, Mini, additional, Kwok, Timothy, additional, Lam, Wai Ping, additional, Lattanzio, Fabrizia, additional, Lawrence, Catherine B., additional, Lee, Tih-Shih, additional, Lee, Yuan-Kai, additional, Leslie, Paula, additional, Leung, Ping Chung, additional, Li, Runping, additional, Liang, Willmann, additional, Lim, Siong-Meng, additional, Lin, Fengwu, additional, Lin, I-Tsung, additional, Loef, Martin, additional, Lovblad, Karl-Olof, additional, Luque, Evelio, additional, Luz, Protásio Lemos da, additional, Macaulay, S.Lance, additional, Madan, Swati, additional, Maetzler, Walter, additional, Mahendran, R., additional, Majeed, Abu Bakar Abdul, additional, Mander, Alastair G., additional, Mani, Vasudevan, additional, Manley, Graham, additional, Manor, Danny, additional, Margetts, Christine, additional, Marini, Elisabetta, additional, Martin-Fernandez, J.Javier, additional, Martínez-Martos, José Manuel, additional, Martínez, Irene Villegas, additional, de Mateo Silleras, Beatriz, additional, Matsuda, Satoru, additional, May, Brian H., additional, McGirr, Alexander, additional, McCormick, Laurie M., additional, Mehta, Jatin, additional, Mereu, Elena, additional, Messina, Antonino, additional, Minami, Akari, additional, Mirowsky, John, additional, Moore, Eileen M., additional, Moreira, Eduardo Luiz Gasnhar, additional, Morelló, José Ramón, additional, Mori, Takashi, additional, Münch, Gerald, additional, Murakami, Kazuma, additional, Mutter, Joachim, additional, Naharci, Mehmet Ilkin, additional, Nakao, Frank Shigeo, additional, Ng, Tze-Pin, additional, Nigro, Julie, additional, Ninomiya, Toshiharu, additional, Nishiyama, Marcelo, additional, Nomani, Erum, additional, Nooyens, Astrid C.J., additional, Oda, Adriana Leico, additional, Okamura, Hitoshi, additional, Oliveira, Acary Souza Bulle, additional, Ono, Yuna, additional, Orsitto, Giuseppe, additional, Ozawa, Mio, additional, Pallet, Véronique, additional, Pamplona, Reinald, additional, Paolisso, Giuseppe, additional, Paradiso, Sergio, additional, Pase, Matthew P., additional, Patki, Gaurav, additional, Piguet, Olivier, additional, Pinto, Alessandro, additional, Pirritano, Domenico, additional, Plastino, Massimiliano, additional, Poggiogalle, Eleonora, additional, Polidori, M.Cristina, additional, Polimanti, Renato, additional, Portero-Otin, Manuel, additional, Power, Brian D., additional, Praticò, Domenico, additional, Prediger, Rui Daniel S., additional, Preedy, Victor R., additional, Prendergast, Mark A., additional, Rae, Daniela, additional, Ramasamy, Kalavathy, additional, Ramli, Muhammad Zaki, additional, Ramirez, Bartolomé, additional, Ramírez-Expósito, María Jesús, additional, Rebec, George V., additional, Reddy, V.Prakash, additional, Redondo del Río, María Paz, additional, Reguant, Jordi, additional, Reisi, Parham, additional, Remington, Ruth, additional, Ricci, Monica, additional, Rizzarelli, Enrico, additional, Robinson, Stephen R., additional, Rogers, Eugene, additional, Rosini, Francesca, additional, Roupas, Peter, additional, Rufa, Alessandra, additional, Russo, María Julieta, additional, Sahathevan, Ramesh, additional, Salim, Samina, additional, Salvioni, Cristina Cleide dos Santos, additional, Sample, Camille H., additional, Santamaría, Abel, additional, Saqqur, Maher, additional, Saragat, Bruno, additional, Sauvant, Julie, additional, Sauvant, Patrick, additional, Scarpini, Elio, additional, Scelza, M.F.Z., additional, Schwen, Richard J., additional, Self, Rachel L., additional, Serrano, José C.E., additional, Shea, Thomas B., additional, Shih, Ping-Hsiao, additional, Shimizu, Takahiko, additional, Shunichiro, Shinagawa, additional, Siahmard, Zahra, additional, Sławek, Jarosław, additional, Smoliner, Christine, additional, Solé, Montse, additional, Sprini, Delia, additional, Squitti, Rosanna, additional, Srulijes, Karin, additional, Stahl, Wilhelm, additional, Stanich, Patricia, additional, Stephens, Brian R., additional, Sun, Mingxue, additional, Takamatsu, Junichi, additional, Tang, Hong Chai, additional, Thandavarayan, Rajarajan A., additional, Torrente, Daniel, additional, Town, Terrence, additional, Túnez, Isaac, additional, Ulatowski, Lynn, additional, Unzeta, Mercedes, additional, Valente, Tony, additional, van Keizerswaard, Jolanda, additional, van de Rest, Ondine, additional, van der Zwaluw, Nikita L., additional, Vecchio, Graziella, additional, Veiga, Judith Jimenez, additional, Vila-Rodriguez, Fidel, additional, Walach, Harald, additional, Warnecke, Tobias, additional, Watters, David A.K., additional, Weber, Wolfgang, additional, Weitzman, Rachel, additional, White, Lon R., additional, Wirth, Rainer, additional, Wu, Chia-Hsien, additional, Xiao, Kai, additional, Xue, Charlie C.L., additional, Yen, Gow-Chin, additional, Yew, David Tai-Wai, additional, Yokoi, Teruo, additional, Zhang, Anthony L., additional, Zhang, Lihong, additional, and Zito, Giancarlo, additional

Published
2015
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16. Smoking and cognitive decline among middle-aged men and women: the Doetinchem Cohort Study

Author

Nooyens, Astrid C.J., van Gelder, Boukje M., and Verschuren, W.M. Monique

Subjects
Smoking -- Health aspects, Smoking -- Psychological aspects, Cognition disorders -- Risk factors, Cognition disorders -- Research, Middle age -- Health aspects, Middle age -- Psychological aspects, Government, Health care industry
Abstract

Objectives. We studied the effect of smoking on cognitive decline over a 5-year period at middle age (43 to 70 years). Methods. In the Doetinchem Cohort Study, 1964 men and women in the Netherlands were examined for cognitive function at baseline and 5 years later. The association between smoking status and memory function, speed of cognitive processes, cognitive flexibility, and global cognitive function were assessed. Results. At baseline, smokers scored lower than never smokers in global cognitive function, speed, and flexibility. At 5-year follow-up, decline among smokers was 1.9 times greater for memory function, 2.4 times greater for cognitive flexibility, and 1.7 times greater for global cognitive function than among never smokers. Among ever smokers, the declines in all cognitive domains were larger with increasing number of pack-years smoked. Conclusions. Interventions to prevent or stop people from smoking may postpone cognitive decline in middle-aged persons. doi:10.2105/AJPH.2007.130294

Published
2008

17. Adherence to dietary guidelines and cognitive decline from middle age:the Doetinchem Cohort Study

Author

Nooyens, Astrid C.J., Yildiz, Berivan, Hendriks, Lisa G., Bas, Sharell, van Boxtel, Martin P.J., Picavet, H. Susan J., Boer, Jolanda M.A., Verschuren, W. M.Monique, Nooyens, Astrid C.J., Yildiz, Berivan, Hendriks, Lisa G., Bas, Sharell, van Boxtel, Martin P.J., Picavet, H. Susan J., Boer, Jolanda M.A., and Verschuren, W. M.Monique

Abstract

BACKGROUND: Diet, in particular the Mediterranean diet, has been associated with better cognitive function and less cognitive decline in older populations. OBJECTIVES: To quantify associations of a healthy diet, defined by adherence to either the Mediterranean diet, the WHO guidelines, or Dutch Health Council dietary guidelines, with cognitive function and cognitive decline from middle age into old age. METHODS: From the Doetinchem Cohort Study, a large population-based longitudinal study, 3644 participants (51% females) aged 45-75 y at baseline, were included. Global cognitive function, memory, processing speed, and cognitive flexibility were assessed at 5-y time intervals up to 20-y follow-up. Adherence to the Mediterranean diet was measured with the modified Mediterranean Diet Score (mMDS), adherence to the WHO dietary guidelines with the Healthy Diet Indicator (HDI), and adherence to the Dutch Health Council dietary guidelines 2015 with the modified Dutch Healthy Diet 2015 index (mDHD15-index). The scores on the dietary indices were classified in tertiles (low, medium, high adherence). Linear mixed models were used to model level and change in cognitive function by adherence to healthy diets. RESULTS: The highest tertiles of the mMDS, HDI, and mDHD15-index were associated with better cognitive function compared with the lowest tertiles (P values <0.01), for instance at age 65 y equal to being 2 y cognitively younger in global cognition. In addition, compared with the lowest tertiles, the highest tertiles of the mMDS, HDI, and mDHD15-index were statistically significantly associated with 6-7% slower global cognitive decline from age 55 to 75 y, but also slower decline in processing speed (for mMDS: 10%; 95% CI: 2, 18%; for mDHD15: 12%; 95% CI: 6, 21%) and cognitive flexibility (for mDHD15: 10%; 95% CI: 4, 18%). CONCLUSIONS: Healthier dietary habits, determined by higher adherence to dietary guidelines, are associated with better cognitive function and slowe

Published
2021

18. Adherence to dietary guidelines and cognitive decline from middle age: the Doetinchem Cohort Study

Author

Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Nooyens, Astrid C J, Yildiz, Berivan, Hendriks, Lisa G, Bas, Sharell, van Boxtel, Martin P J, Picavet, H Susan J, Boer, Jolanda M A, Verschuren, W M Monique, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovascular Health, Nooyens, Astrid C J, Yildiz, Berivan, Hendriks, Lisa G, Bas, Sharell, van Boxtel, Martin P J, Picavet, H Susan J, Boer, Jolanda M A, and Verschuren, W M Monique

Published
2021

19. Dementia incidence trend over 1992-2014 in the Netherlands: Analysis of primary care data

Author

van Bussel, Emma F., Richard, Edo, Arts, Derk L., Nooyens, Astrid C. J., Coloma, Preciosa M., de Waal, Margot W. M., van den Akker, Marjan, Biermans, Marion C. J., Nielen, Markus M. J., van Boven, Kees, Smeets, Hugo, Matthews, Fiona E., Brayne, Carol, Busschers, Wim B., van Gool, Willem A., and Moll van Charante, Eric P.

Subjects
Usage, Research, Risk factors, Demographic aspects, Medical records -- Usage -- Research, Dementia -- Analysis -- Risk factors -- Demographic aspects -- Research
Abstract

Author(s): Emma F. van Bussel 1,*, Edo Richard 2,3, Derk L. Arts 1, Astrid C. J. Nooyens 4, Preciosa M. Coloma 5, Margot W. M. de Waal 6, Marjan van [...], Background Recent reports have suggested declining age-specific incidence rates of dementia in high-income countries over time. Improved education and cardiovascular health in early age have been suggested to be bringing about this effect. The aim of this study was to estimate the age-specific dementia incidence trend in primary care records from a large population in the Netherlands. Methods and findings A dynamic cohort representative of the Dutch population was composed using primary care records from general practice registration networks (GPRNs) across the country. Data regarding dementia incidence were obtained using general-practitioner-recorded diagnosis of dementia within the electronic health records. Age-specific dementia incidence rates were calculated for all persons aged 60 y and over; negative binomial regression analysis was used to estimate the time trend. Nine out of eleven GPRNs provided data on more than 800,000 older people for the years 1992 to 2014, corresponding to over 4 million person-years and 23,186 incident dementia cases. The annual growth in dementia incidence rate was estimated to be 2.1% (95% CI 0.5% to 3.8%), and incidence rates were 1.08 (95% CI 1.04 to 1.13) times higher for women compared to men. Despite their relatively low numbers of person-years, the highest age groups contributed most to the increasing trend. There was no significant overall change in incidence rates since the start of a national dementia program in 2003 (-0.025; 95% CI -0.062 to 0.011). Increased awareness of dementia by patients and doctors in more recent years may have influenced dementia diagnosis by general practitioners in electronic health records, and needs to be taken into account when interpreting the data. Conclusions Within the clinical records of a large, representative sample of the Dutch population, we found no evidence for a declining incidence trend of dementia in the Netherlands. This could indicate true stability in incidence rates, or a balance between increased detection and a true reduction. Irrespective of the exact rates and mechanisms underlying these findings, they illustrate that the burden of work for physicians and nurses in general practice associated with newly diagnosed dementia has not been subject to substantial change in the past two decades. Hence, with the ageing of Western societies, we still need to anticipate a dramatic absolute increase in dementia occurrence over the years to come.

Published
2017
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24. Sex differences in physical performance by age, educational level, ethnic groups and birth cohort: The Longitudinal Aging Study Amsterdam

Author

Sialino, Lena D., primary, Schaap, Laura A., additional, van Oostrom, Sandra H., additional, Nooyens, Astrid C. J., additional, Picavet, Hendrika S. J., additional, Twisk, Johannes W. R., additional, Verschuren, W. M. Monique, additional, Visser, Marjolein, additional, and Wijnhoven, Hanneke A. H., additional

Published
2019
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28. Sex differences in physical performance by age, educational level, ethnic groups and birth cohort : The Longitudinal Aging Study Amsterdam

Author

Sialino, Lena D, Schaap, Laura A, van Oostrom, Sandra H, Nooyens, Astrid C J, Picavet, Hendrika S J, Twisk, Johannes W R, Verschuren, W M Monique, Visser, Marjolein, Wijnhoven, Hanneke A H, Sialino, Lena D, Schaap, Laura A, van Oostrom, Sandra H, Nooyens, Astrid C J, Picavet, Hendrika S J, Twisk, Johannes W R, Verschuren, W M Monique, Visser, Marjolein, and Wijnhoven, Hanneke A H

Published
2019

29. Sex differences in physical performance by age, educational level, ethnic groups and birth cohort: The Longitudinal Aging Study Amsterdam

Author

Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Sialino, Lena D, Schaap, Laura A, van Oostrom, Sandra H, Nooyens, Astrid C J, Picavet, Hendrika S J, Twisk, Johannes W R, Verschuren, W M Monique, Visser, Marjolein, Wijnhoven, Hanneke A H, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Sialino, Lena D, Schaap, Laura A, van Oostrom, Sandra H, Nooyens, Astrid C J, Picavet, Hendrika S J, Twisk, Johannes W R, Verschuren, W M Monique, Visser, Marjolein, and Wijnhoven, Hanneke A H

Published
2019

30. Gender and Educational Differences in the Association between Lifestyle and Cognitive Decline over 10 Years: The Doetinchem Cohort Study

Author

Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Deckers, Kay, Nooyens, Astrid, van Boxtel, Martin, Verhey, Frans, Verschuren, Monique, Köhler, Sebastian, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Deckers, Kay, Nooyens, Astrid, van Boxtel, Martin, Verhey, Frans, Verschuren, Monique, and Köhler, Sebastian

Published
2019

32. Fish consumption, intake of fats and cognitive decline at middle and older age: the Doetinchem Cohort Study

Author

MS MDL 1, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C J, Van Gelder, Boukje M., Bueno-de-Mesquita, H Bas, Van Boxtel, Martin P J, Verschuren, W M Monique, MS MDL 1, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C J, Van Gelder, Boukje M., Bueno-de-Mesquita, H Bas, Van Boxtel, Martin P J, and Verschuren, W M Monique

Published
2018

33. Long sleep duration is associated with lower cognitive function among middle-age adults – the Doetinchem Cohort Study

Author

Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, van Oostrom, Sandra H., Nooyens, Astrid C.J., van Boxtel, Martin P.J., Verschuren, W. M.Monique, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, van Oostrom, Sandra H., Nooyens, Astrid C.J., van Boxtel, Martin P.J., and Verschuren, W. M.Monique

Published
2018

34. Health literacy among older adults is associated with their 10-years' cognitive functioning and decline - the Doetinchem Cohort Study

Author

Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Geboers, Bas, Uiters, Ellen, Reijneveld, Sijmen A, Jansen, Carel J M, Almansa, Josué, Nooyens, Astrid C J, Verschuren, W M Monique, de Winter, Andrea F, Picavet, H Susan J, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Geboers, Bas, Uiters, Ellen, Reijneveld, Sijmen A, Jansen, Carel J M, Almansa, Josué, Nooyens, Astrid C J, Verschuren, W M Monique, de Winter, Andrea F, and Picavet, H Susan J

Published
2018

37. Plasma biomarkers of endothelial dysfunction and cognition: an IPD meta-analysis of cross- sectional data from 9,344 individuals from seven Dutch cohorts

Author

Beran, Magdalena, Jansen, Willemijn J., Oomens, Julie E., Moonen, Justine E.F., Visser, Pieter Jelle, Huisman, Martijn A., Kok, Almar A.L., Nooyens, Astrid C.J., Verschuren, W.M. Monique, Stehouwer, Coen D.A., Schalkwijk, Casper, Köhler, Sebastian, van Boxtel, Martin, Beekman, Marian, Slagboom, P. Eline, Wolters, Frank J., Ikram, M. Arfan, Vallerga, Costanza L., van Meurs, Joyce B.J., Ghanbari, Mohsen, Vonk, Jet M.J., Geerlings, Mirjam I., van Sloten, Thomas T., and Schram, Miranda T.

Abstract

Endothelial dysfunction has various detrimental effects on the brain that may lead to cognitive decline. However, data on the direct association between endothelial dysfunction and cognitive performance in humans are scarce. The aim of the present study was to assess the cross-sectional association between plasma biomarkers of endothelial dysfunction and cognitive performance.

Published
2024
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38. Diet and cognitive decline at middle age : The role of antioxidants

Author

Nooyens, Astrid C J, Milder, Ivon E J, Van Gelder, Boukje M., Bueno-De-Mesquita, H. Bas, Van Boxtel, Martin P J, Verschuren, W. M Monique, Nooyens, Astrid C J, Milder, Ivon E J, Van Gelder, Boukje M., Bueno-De-Mesquita, H. Bas, Van Boxtel, Martin P J, and Verschuren, W. M Monique

Published
2015

39. Diet and cognitive decline at middle age: The role of antioxidants

Author

MS MDL 1, Cancer, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C J, Milder, Ivon E J, Van Gelder, Boukje M., Bueno-De-Mesquita, H. Bas, Van Boxtel, Martin P J, Verschuren, W. M Monique, MS MDL 1, Cancer, Public Health Epidemiologie, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Nooyens, Astrid C J, Milder, Ivon E J, Van Gelder, Boukje M., Bueno-De-Mesquita, H. Bas, Van Boxtel, Martin P J, and Verschuren, W. M Monique

Published
2015

44. Effects of retirement on lifestyle in relation to changes in weight and waist circumference in Dutch men: a prospective study

Author

Nooyens, Astrid C J, Visscher, Tommy L S, Schuit, A Jantine, van Rossum, Caroline T M, Verschuren, W M Monique, van Mechelen, Willem, Seidell, Jacob C, Nooyens, Astrid C J, Visscher, Tommy L S, Schuit, A Jantine, van Rossum, Caroline T M, Verschuren, W M Monique, van Mechelen, Willem, and Seidell, Jacob C

Abstract

OBJECTIVE: To study changes in lifestyle in relation to changes in body weight and waist circumference associated with occupational retirement in men.DESIGN: A prospective cohort study with 5 years of follow-up. At baseline and at follow-up, questionnaires were completed and body weight and waist circumference were measured.SETTING: The Doetinchem Cohort Study, consisting of inhabitants of Doetinchem, a town in a rural area of The Netherlands.SUBJECTS: In total 288 healthy men aged 50-65 years at baseline, who either remained employed or retired over follow-up.RESULTS: The effect of retirement on changes in weight and waist circumference was dependent on type of former occupation. Increase in body weight and waist circumference was higher among men who retired from active jobs (0.42 kg year(-1) and 0.77 cm year(-1), respectively) than among men who retired from sedentary jobs (0.08 kg year(-1) and 0.23 cm year(-1), respectively). Weight gain and increase in waist circumference were associated with a decrease in fruit consumption and fibre density of the diet, with an increase in frequency of eating breakfast, and with a decrease in several physical activities, such as household activities, bicycling, walking and doing odd jobs.CONCLUSION: Retirement was associated with an increase in weight and waist circumference among those with former active jobs, but not among those with former sedentary jobs. Retirement may bring opportunities for healthy changes in diet and physical activity, which could be used in health promotion programmes.

Published
2005
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49. Consumption of alcoholic beverages and cognitive decline at middle age: the Doetinchem Cohort Study.

Author

Nooyens, Astrid C. J., Bueno-de-Mesquita, H. Bas, van Gelder, Boukje M., van Boxtel, Martin P. J., and Verschuren, W. M. Monique

Subjects
AGING, ALCOHOLIC beverages, ANALYSIS of covariance, BLOOD pressure, BODY weight, CHOLESTEROL, COGNITION, DOSE-response relationship in biochemistry, HIGH density lipoproteins, LONGITUDINAL method, NEUROPSYCHOLOGICAL tests, PROBABILITY theory, QUESTIONNAIRES, REGRESSION analysis, RESEARCH funding, SMOKING, STATISTICS, DATA analysis, LIFESTYLES, PHYSICAL activity, DATA analysis software, WAIST circumference
Abstract

Accelerated cognitive decline increases the risk of dementia. Slowing down the rate of cognitive decline leads to the preservation of cognitive functioning in the elderly, who can live independently for a longer time. Alcohol consumption may influence the rate of cognitive decline. The aim of the present study was to evaluate the associations between the total consumption of alcoholic beverages and different types of alcoholic beverages and cognitive decline at middle age. In 2613 men and women of the Doetinchem Cohort Study, aged 43–70 years at baseline (1995–2002), cognitive function (global cognitive function and the domains memory, speed and flexibility) was assessed twice, with a 5-year time interval. In linear regression analyses, the consumption of different types of alcoholic beverages was analysed in relation to cognitive decline, adjusting for confounders. We observed that, in women, the total consumption of alcoholic beverages was inversely associated with the decline in global cognitive function over a 5-year period (P for trend = 0·02), while no association was observed in men. Regarding the consumption of different types of alcoholic beverages in men and women together, red wine consumption was inversely associated with the decline in global cognitive function (P for trend < 0·01) as well as memory (P for trend < 0·01) and flexibility (P for trend = 0·03). Smallest declines were observed at a consumption of about 1·5 glasses of red wine per d. No other types of alcoholic beverages were associated with cognitive decline. In conclusion, only (moderate) red wine consumption was consistently associated with less strong cognitive decline. Therefore, it is most likely that non-alcoholic substances in red wine are responsible for any cognition-preserving effects. [ABSTRACT FROM PUBLISHER]

Published
2014
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50. All-cause mortality risk of metabolically healthy abdominal obese individuals: The EPIC-MORGEN study.

Author

van der A, Daphne L., Nooyens, Astrid C.J., van Duijnhoven, Fränzel J.B., Verschuren, Monique M.W., and Boer, Jolanda M.A.

Subjects
OVERWEIGHT persons, MORTALITY, OBESITY, ABDOMINAL adipose tissue, ADIPOSE tissues
Abstract

Objective It appears that a certain proportion of obese individuals have a normal metabolic profile despite having excess weight. Whether these so-called 'metabolically healthy' obese express lower disease and mortality risks than 'metabolically unhealthy' obese is still unclear. The mortality risk of 'metabolically healthy' abdominal obese (MHAO) individuals was investigated. Design and Methods Prospective cohort study (EPIC-MORGEN) among 22,654 individuals aged 20-59 years followed for an average of 13.4 years (SD 2.3). MHAO was assessed at baseline (1993-1997) and defined as abdominal obesity (waist circumference ≥102 cm/≥88 cm (men/women)) with normal glucose, blood pressure, and plasma lipids. All-cause mortality risks adjusted for age and sex were estimated using Cox proportional hazards models. Results Individuals who were 'metabolically healthy' nonabdominal obese (MHNAO) comprised the reference group. As compared to MHNAO, mortality risk for MHAO was around 40% higher (Hazard ratio (HR) 1.43; 95% confidence interval (CI): 1.00-2.04) and of the same magnitude as that for 'metabolically unhealthy' nonabdominal obese (MUNAO) (HR 1.31; 95% CI: 1.08-1.59). The HR for MUAO was 1.99 (95% CI: 1.62-2.43). Conclusions Mortality risk of MHAO individuals was significantly higher than that of MHNAO individuals and lower than, but not statistically significantly different from, that of MUAO individuals. [ABSTRACT FROM AUTHOR]

Published
2014
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