Plasma biomarkers of endothelial dysfunction and cognition: an IPD meta-analysis of cross- sectional data from 9,344 individuals from seven Dutch cohorts

Authors :: Beran, Magdalena
Jansen, Willemijn J.
Oomens, Julie E.
Moonen, Justine E.F.
Visser, Pieter Jelle
Huisman, Martijn A.
Kok, Almar A.L.
Nooyens, Astrid C.J.
Verschuren, W.M. Monique
Stehouwer, Coen D.A.
Schalkwijk, Casper
Köhler, Sebastian
van Boxtel, Martin
Beekman, Marian
Slagboom, P. Eline
Wolters, Frank J.
Ikram, M. Arfan
Vallerga, Costanza L.
van Meurs, Joyce B.J.
Ghanbari, Mohsen
Vonk, Jet M.J.
Geerlings, Mirjam I.
van Sloten, Thomas T.
Schram, Miranda T.
Source :: Cerebral Circulation - Cognition and Behavior; January 2024, Vol. 6 Issue: 1, Number 1 Supplement 1
Publication Year :: 2024
Abstract: Endothelial dysfunction has various detrimental effects on the brain that may lead to cognitive decline. However, data on the direct association between endothelial dysfunction and cognitive performance in humans are scarce. The aim of the present study was to assess the cross-sectional association between plasma biomarkers of endothelial dysfunction and cognitive performance.

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