171 results on '"Newsom-Davis, Thomas"'
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2. SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
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Evans, Joanne S, Swallow, Judith, Hanbury, Georgina, Chung, Chris, Patel, Meera, Dettorre, Gino, Belessiotis, Katherine, Saorise, Dolly, Jones, Eleanor, Apthorp, Eleanor, Moss, Charlotte, Russell, Beth, Townsend, Sarah, Jackson, Amanda, Loizidou, Angela, Piccart, Martine, Pommeret, Fanny, Colomba-Blameble, Emeline, Prat, Aleix, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Viladot, Margarita, Harbeck, Nadia, Wuerstlein, Rachel, Henze, Franziska, Mahner, Sven, Felip, Eudald, Scotti, Lorenza, Marrari, Andrea, Grosso, Federica, Fusco, Vittorio, Delfanti, Sara, Rossi, Maura, Zambelli, Alberto, Tondini, Carlo, Chiudinelli, Lorenzo, Franchi, Michela, Libertini, Michela, Provenzano, Salvatore, Generali, Daniele, Grisanti, Salvatore, Baggi, Alice, Tovazzi, Valeria, Ficorella, Corrado, Porzio, Giampiero, Saponara, Maristella, Filetti, Marco, Tucci, Marco, Berardi, Rossana, Cantini, Luca, Paoloni, Francesco, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Sanchez de Torre, Ana, Tagliamento, Marco, Cortellini, Alessio, Tabernero, Josep, Mukherjee, Uma, Salazar, Ramon, Sureda, Anna, Maluquer, Clara, Ferrante, Daniela, Bower, Mark, Sharkey, Rachel, Mirallas, Oriol, Plaja, Andrea, Cucurull, Marc, Mesia, Ricard, Dalla Pria, Alessia, Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Sita-Lumsden, Ailsa, Vincenzi, Bruno, Di Fazio, Giuseppina Rita, Tonini, Giuseppe, Pantano, Francesco, Bertuzzi, Alexia, Rossi, Sabrina, Brunet, Joan, Lambertini, Matteo, Pedrazzoli, Paolo, Biello, Federica, D'Avanzo, Francesca, Lee, Alvin J X, Shawe-Taylor, Marianne, Rogers, Lucy, Murphy, Cian, Cooper, Lee, Andaleeb, Ramis, Khalique, Saira, Bawany, Samira, Ahmed, Sarah, Carmona-García, M Carmen, Fort-Culillas, Roser, Liñan, Raquel, Zoratto, Federica, Rizzo, Gianpiero, Perachino, Marta, Doonga, Kris, Gaidano, Gianluca, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Pérez Criado, Ignacio, Giusti, Raffaele, Mazzoni, Francesca, Antonuzzo, Lorenzo, Santoro, Armando, Parisi, Alessandro, Queirolo, Paola, Aujayeb, Avinash, Rimassa, Lorenza, Diamantis, Nikolaos, Bertulli, Rossella, Fulgenzi, Claudia A M, D'Alessio, Antonio, Ruiz-Camps, Isabel, Saoudi-Gonzalez, Nadia, Garcia Illescas, David, Medina, Irene, Fox, Laura, Gennari, Alessandra, Aguilar-Company, Juan, and Pinato, David J
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- 2023
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3. Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study
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Evans, Joanne S, Swallow, Judith, Chung, Chris, Patel, Meera, Dettorre, Gino, Ottaviani, Diego, Chowdhury, Amani, Merry, Eve, Chopra, Neha, Lee, Alvin JX, Sng, Christopher CT, Yu, Tamara, Shawe-Taylor, Marianne, Bain, Hamish DC, Wong, Yien Ning Sophia, Galazi, Myria, Benafif, Sarah, Dileo, Palma, Earnshaw, Irina, Patel, Grisma, Wu, Anjui, Soosaipillai, Gehan, Cooper, Lee, Andaleeb, Ramis, Dolly, Saoirse, Apthorp, Eleanor, Srikandarajah, Krishnie, Jones, Eleanor, Van Hemelrijck, Mieke, Moss, Charlotte, Russell, Beth, Chester, John, Loizidou, Angela, Piccart, Martine, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Viladot, Margarita, Eremiev, Simeon, Fort-Culillas, Roser, Garcia, Isabel, Liñan, Raquel, Roqué Lloveras, Ariadna, Harbeck, Nadia, Wuerstlein, Rachel, Henze, Franziska, Mahner, Sven, Felip, Eudald, Pous, Anna, D'Avanzo, Francesca, Scotti, Lorenza, Krengli, Marco, Marrari, Andrea, Delfanti, Sara, Maconi, Antonio, Betti, Marta, Tonini, Giuseppe, Di Fazio, Giuseppina Rita, Tondini, Carlo, Chiudinelli, Lorenzo, Franchi, Michela, Libertini, Michela, Bertulli, Rossella, Baggi, Alice, Tovazzi, Valeria, Ficorella, Corrado, Porzio, Giampiero, Saponara, Maristella, Filetti, Marco, Zoratto, Federica, Paoloni, Francesco, Berardi, Rossana, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Sanchez de Torre, Ana, Tagliamento, Marco, Colomba, Emeline, Pommeret, Fanny, Pinato, David J, Aguilar-Company, Juan, Ferrante, Daniela, Hanbury, Georgina, Bower, Mark, Salazar, Ramon, Mirallas, Oriol, Sureda, Anna, Plaja, Andrea, Cucurull, Marc, Mesia, Ricard, Townsend, Sarah, Jackson, Amanda, Dalla Pria, Alessia, Newsom-Davis, Thomas, Handford, Jasmine, Sita-Lumsden, Ailsa, Vincenzi, Bruno, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Biello, Federica, Sinclair, Alasdair, Bawany, Samira, Khalique, Saira, Rossi, Sabrina, Rogers, Lucy, Murphy, Cian, Belessiotis, Katherine, Carmona-García, M Carmen, Sharkey, Rachel, García-Illescas, David, Rizzo, Gianpiero, Perachino, Marta, Saoudi-Gonzalez, Nadia, Doonga, Kris, Fox, Laura, Roldán, Elisa, Gaidano, Gianluca, Ruiz-Camps, Isabel, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Cantini, Luca, Zambelli, Alberto, Giusti, Raffaele, Mazzoni, Francesca, Caliman, Enrico, Santoro, Armando, Grosso, Federica, Parisi, Alessandro, Queirolo, Paola, Aujayeb, Avinash, Rimassa, Lorenza, Prat, Aleix, Tucci, Marco, Grisanti, Salvatore, Mukherjee, Uma, Diamantis, Nikolaos, Fusco, Vittorio, Generali, Daniele, Provenzano, Salvatore, Gennari, Alessandra, Tabernero, Josep, and Cortellini, Alessio
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- 2022
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4. Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study
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Swallow, Judith, Chung, Chris, Dettorre, Gino, Chopra, Neha, Lee, Alvin JX, Sng, Christopher CT, Wong, Yien Ning Sophia, Galazi, Myria, Benafif, Sarah, Dileo, Palma, Patel, Grisma, Wu, Anjui, Sinclair, Alasdair, Soosaipillai, Gehan, Jones, Eleanor, Diamantis, Nikolaos, Mukherjee, Uma, Jackson, Amanda, Piccart, Martine, Pommeret, Fanny, Colomba, Johann, Colomba-Blameble, Emeline, Prat, Aleix, Cruz, Claudia A, Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Tabernero, Josep, Aguilar-Company, Juan, Ruiz-Camps, Isabel, Fox, Laura, Garcia Illescas, David, Mirallas, Oriol, Roldán, Elisa, Carbó, Anna, Garcia, Isabel, Wuerstlein, Rachel, Mesia, Ricard, Maluquer, Clara, D'Avanzo, Francesca, Tonini, Giuseppe, Provenzano, Salvatore, Tovazzi, Valeria, Ficorella, Corrado, Queirolo, Paola, Giusti, Raffaele, Mazzoni, Francesca, Zoratto, Federica, Tucci, Marco, Berardi, Rossana, Guida, Annalisa, Bracarda, Sergio, Iglesias, Maria, Pinato, David J, Bower, Mark, Scotti, Lorenza, Patel, Meera, Colomba, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Zambelli, Alberto, Dalla Pria, Alessia, Ottaviani, Diego, Chowdhury, Amani, Merry, Eve, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Tagliamento, Marco, Pous, Anna, Sita-Lumsden, Ailsa, Srikandarajah, Krishnie, Seguí, Elia, Generali, Daniele, Grisanti, Salvatore, Pedrazzoli, Paolo, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S, Russell, Beth, Harbeck, Nadia, Vincenzi, Bruno, Biello, Federica, Bertulli, Rossella, Liñan, Raquel, Rossi, Sabrina, Carmona-García, Maria Carmen, Tondini, Carlo, Baggi, Alice, Fotia, Vittoria, Parisi, Alessandro, Porzio, Giampero, Saponara, Maristella, Cruz, Claudia Andrea, García-Illescas, David, Felip, Eudald, Roqué Lloveras, Ariadna, Sharkey, Rachel, Earnshaw, Irina, Ferrante, Daniela, Gaidano, Gianluca, Patriarca, Andrea, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Cantini, Luca, Filetti, Marco, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Van Hemelrijck, Mieke, Newsom-Davis, Thomas, Gennari, Alessandra, and Cortellini, Alessio
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- 2021
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5. 192 Stereotactic radiofrequency ventral posterolateral thalamotomy – an effective treatment for complex pain in lung cancer?
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Teh, Zoe, primary, Newsom-Davis, Thomas, additional, Cox, Sarah, additional, Brown, Matthew, additional, Pereira, Erlick, additional, and Caulkin, Ruth, additional
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- 2024
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6. CONTACT-01: A Randomized Phase III Trial of Atezolizumab + Cabozantinib Versus Docetaxel for Metastatic Non–Small Cell Lung Cancer After a Checkpoint Inhibitor and Chemotherapy
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Neal, Joel, primary, Pavlakis, Nick, additional, Kim, Sang-We, additional, Goto, Yasushi, additional, Lim, Sun Min, additional, Mountzios, Giannis, additional, Fountzilas, Elena, additional, Mochalova, Anastasia, additional, Christoph, Daniel C., additional, Bearz, Alessandra, additional, Quantin, Xavier, additional, Palmero, Ramon, additional, Antic, Vladan, additional, Chun, Elaine, additional, Edubilli, Tirupathi Rao, additional, Lin, Ya-Chen, additional, Huseni, Mahrukh, additional, Ballinger, Marcus, additional, Graupner, Vilma, additional, Curran, Dominic, additional, Vervaet, Piet, additional, and Newsom-Davis, Thomas, additional
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- 2024
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7. COVID-19 and the multidisciplinary care of patients with lung cancer: an evidence-based review and commentary
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Round, Thomas, L’Esperance, Veline, Bayly, Joanne, Brain, Kate, Dallas, Lorraine, Edwards, John G., Haswell, Thomas, Hiley, Crispin, Lovell, Natasha, McAdam, Julia, McCutchan, Grace, Nair, Arjun, Newsom-Davis, Thomas, Sage, Elizabeth K., and Navani, Neal
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- 2021
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8. Multimodality local consolidative treatment versus conventional care of advanced lung cancer after first-line systemic anti-cancer treatment: study protocol for the RAMON multicentre randomised controlled trial with an internal pilot
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Beard, Chloe, primary, Rogers, Chris A, additional, Fleming, Leah, additional, Conibear, John, additional, Evison, Matthew, additional, Newsom-Davis, Thomas, additional, Barwick, Tara, additional, Mills, Nicola, additional, Stokes, Elizabeth A, additional, De Sousa, Paulo, additional, Batchelor, Tim, additional, Rawlinson, Janette, additional, Baos, Sarah, additional, Harris, Rosie, additional, and Lim, Eric, additional
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- 2023
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9. Fas Ligand and Tumour Immunology
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Newsom-Davis, Thomas Edmund
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616.994 - Abstract
Fas ligand (FasL) is a transmembrane protein which induces apoptosis in cells expressing its receptor, Fas. The FasL/Fas pathway is one ofthe major mediators of cell death in the immune system but more recently an inflammatory role has been suggested. This thesis investigated the finding that when injected into mice, FasL-expressing (FasL+) tumours recruit a massive polymorphonuclear neutrophil (PMN) infiltration and are then rejected, which is followed by the development of antibody mediated tumour immunity. . In this work, eight IgM and one IgG2a monoclonal antibodies (mAbs) were produced from mice vaccinated with FasL+ murine melanoma. They recognised various syngeneic and allogeneic murine tumours cell lines. One mAb, TMIO, also recognised a range of human tumours cell lines but not untransformed cells. The epitopes of all the mAbs were carbohydrates expressed on proteins and/or lipids. The epitope of TMIO were high-mannose clusters on N-linked glycoproteins whilst another antibody, KM5.2, was recognising the glycolipid GM4. Both are novel tumour antigens. The IgG2a mAb had in vivp anti-tumour activity, protecting mice against the development ofboth cutaneous and metatstatic melanoma through antibody dependent cellular cytotoxicity. T~e mechanism behind the rejection and immunity to FasL+ tumours was studied using human cells. FasL promoted the production of chemokines by PMNs. PMNs, but not FasL, induced maturation of dendritic cells with a corresponding increase in T cell proliferation. FasL inhibited the generation of the THI subset ofCD4+ T cells, whereas PMNs promoted THI polansation and increased 1NFa and IL-22 production. -- , A model is proposed in which PMNs attracted to the tumour site promote rejection of FasL+ tumours by creating an inflammatory environment whilst recruiting and activating effector cells. They then induce antibody-mediated tumour immunity by facilitating the T cell help required. PMNs therefore act as a bridge between the innate and adaptive immune responses.
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- 2008
10. Applicability of Routine Targeted Next-generation Sequencing to Estimate Tumor Mutational Burden (TMB) in Patients Treated With Immune Checkpoint Inhibitor Therapy
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Pinato, David J., Urus, Heather, Newsom-Davis, Thomas, Du Parcq, Persephone, Belessiotis, Katherine, Mapara, Leah, Gupta, Nandita, Power, Danielle, Weir, Justin, Wong, Ching Ngar, Ratnakumaran, Ragu P., Dominy, Kathy, Khorashad, Jamshid, and Bower, Mark
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- 2020
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11. Data from Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer
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Pinato, David J., primary, Zambelli, Alberto, primary, Aguilar-Company, Juan, primary, Bower, Mark, primary, Sng, Christopher C.T., primary, Salazar, Ramon, primary, Bertuzzi, Alexia, primary, Brunet, Joan, primary, Mesia, Ricard, primary, Seguí, Elia, primary, Biello, Federica, primary, Generali, Daniele, primary, Grisanti, Salvatore, primary, Rizzo, Gianpiero, primary, Libertini, Michela, primary, Maconi, Antonio, primary, Harbeck, Nadia, primary, Vincenzi, Bruno, primary, Bertulli, Rossella, primary, Ottaviani, Diego, primary, Carbó, Anna, primary, Bruna, Riccardo, primary, Benafif, Sarah, primary, Marrari, Andrea, primary, Wuerstlein, Rachel, primary, Carmona-Garcia, M. Carmen, primary, Chopra, Neha, primary, Tondini, Carlo, primary, Mirallas, Oriol, primary, Tovazzi, Valeria, primary, Betti, Marta, primary, Provenzano, Salvatore, primary, Fotia, Vittoria, primary, Cruz, Claudia Andrea, primary, Dalla Pria, Alessia, primary, D'Avanzo, Francesca, primary, Evans, Joanne S., primary, Saoudi-Gonzalez, Nadia, primary, Felip, Eudald, primary, Galazi, Myria, primary, Garcia-Fructuoso, Isabel, primary, Lee, Alvin J.X., primary, Newsom-Davis, Thomas, primary, Patriarca, Andrea, primary, García-Illescas, David, primary, Reyes, Roxana, primary, Dileo, Palma, primary, Sharkey, Rachel, primary, Wong, Yien Ning Sophia, primary, Ferrante, Daniela, primary, Marco-Hernández, Javier, primary, Sureda, Anna, primary, Maluquer, Clara, primary, Ruiz-Camps, Isabel, primary, Gaidano, Gianluca, primary, Rimassa, Lorenza, primary, Chiudinelli, Lorenzo, primary, Izuzquiza, Macarena, primary, Cabirta, Alba, primary, Franchi, Michela, primary, Santoro, Armando, primary, Prat, Aleix, primary, Tabernero, Josep, primary, Gennari, Alessandra, primary, Avanzi, Gian Carlo, primary, Bellan, Mattia, primary, Castello, Luigi Mario, primary, Martinez, Maria, primary, Mollà, Meritxell, primary, Pirisi, Mario, primary, Scotti, Lorenza, primary, and Swallow, Judith, primary
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- 2023
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12. Supplementary Data from Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer
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Pinato, David J., primary, Zambelli, Alberto, primary, Aguilar-Company, Juan, primary, Bower, Mark, primary, Sng, Christopher C.T., primary, Salazar, Ramon, primary, Bertuzzi, Alexia, primary, Brunet, Joan, primary, Mesia, Ricard, primary, Seguí, Elia, primary, Biello, Federica, primary, Generali, Daniele, primary, Grisanti, Salvatore, primary, Rizzo, Gianpiero, primary, Libertini, Michela, primary, Maconi, Antonio, primary, Harbeck, Nadia, primary, Vincenzi, Bruno, primary, Bertulli, Rossella, primary, Ottaviani, Diego, primary, Carbó, Anna, primary, Bruna, Riccardo, primary, Benafif, Sarah, primary, Marrari, Andrea, primary, Wuerstlein, Rachel, primary, Carmona-Garcia, M. Carmen, primary, Chopra, Neha, primary, Tondini, Carlo, primary, Mirallas, Oriol, primary, Tovazzi, Valeria, primary, Betti, Marta, primary, Provenzano, Salvatore, primary, Fotia, Vittoria, primary, Cruz, Claudia Andrea, primary, Dalla Pria, Alessia, primary, D'Avanzo, Francesca, primary, Evans, Joanne S., primary, Saoudi-Gonzalez, Nadia, primary, Felip, Eudald, primary, Galazi, Myria, primary, Garcia-Fructuoso, Isabel, primary, Lee, Alvin J.X., primary, Newsom-Davis, Thomas, primary, Patriarca, Andrea, primary, García-Illescas, David, primary, Reyes, Roxana, primary, Dileo, Palma, primary, Sharkey, Rachel, primary, Wong, Yien Ning Sophia, primary, Ferrante, Daniela, primary, Marco-Hernández, Javier, primary, Sureda, Anna, primary, Maluquer, Clara, primary, Ruiz-Camps, Isabel, primary, Gaidano, Gianluca, primary, Rimassa, Lorenza, primary, Chiudinelli, Lorenzo, primary, Izuzquiza, Macarena, primary, Cabirta, Alba, primary, Franchi, Michela, primary, Santoro, Armando, primary, Prat, Aleix, primary, Tabernero, Josep, primary, Gennari, Alessandra, primary, Avanzi, Gian Carlo, primary, Bellan, Mattia, primary, Castello, Luigi Mario, primary, Martinez, Maria, primary, Mollà, Meritxell, primary, Pirisi, Mario, primary, Scotti, Lorenza, primary, and Swallow, Judith, primary
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- 2023
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13. SARS-CoV-2 omicron (B.1.1.529)-related COVID-19 sequelae in vaccinated and unvaccinated patients with cancer: results from the OnCovid registry
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Cortellini, Alessio, primary, Tabernero, Josep, additional, Mukherjee, Uma, additional, Salazar, Ramon, additional, Sureda, Anna, additional, Maluquer, Clara, additional, Ferrante, Daniela, additional, Bower, Mark, additional, Sharkey, Rachel, additional, Mirallas, Oriol, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, Mesia, Ricard, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Van Hemelrijck, Mieke, additional, Sita-Lumsden, Ailsa, additional, Apthorp, Eleanor, additional, Vincenzi, Bruno, additional, Di Fazio, Giuseppina Rita, additional, Tonini, Giuseppe, additional, Pantano, Francesco, additional, Bertuzzi, Alexia, additional, Rossi, Sabrina, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, D'Avanzo, Francesca, additional, Lee, Alvin J X, additional, Shawe-Taylor, Marianne, additional, Rogers, Lucy, additional, Murphy, Cian, additional, Cooper, Lee, additional, Andaleeb, Ramis, additional, Khalique, Saira, additional, Bawany, Samira, additional, Ahmed, Sarah, additional, Carmona-García, M Carmen, additional, Fort-Culillas, Roser, additional, Liñan, Raquel, additional, Zoratto, Federica, additional, Rizzo, Gianpiero, additional, Perachino, Marta, additional, Doonga, Kris, additional, Gaidano, Gianluca, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Martinez-Vila, Clara, additional, Pérez Criado, Ignacio, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Antonuzzo, Lorenzo, additional, Santoro, Armando, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Diamantis, Nikolaos, additional, Bertulli, Rossella, additional, Fulgenzi, Claudia A M, additional, D'Alessio, Antonio, additional, Ruiz-Camps, Isabel, additional, Saoudi-Gonzalez, Nadia, additional, Garcia Illescas, David, additional, Medina, Irene, additional, Fox, Laura, additional, Gennari, Alessandra, additional, Aguilar-Company, Juan, additional, Pinato, David J, additional, Evans, Joanne S, additional, Swallow, Judith, additional, Hanbury, Georgina, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Belessiotis, Katherine, additional, Saorise, Dolly, additional, Jones, Eleanor, additional, Moss, Charlotte, additional, Russell, Beth, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Pommeret, Fanny, additional, Colomba-Blameble, Emeline, additional, Prat, Aleix, additional, Cruz, Claudia A, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Felip, Eudald, additional, Scotti, Lorenza, additional, Marrari, Andrea, additional, Grosso, Federica, additional, Fusco, Vittorio, additional, Delfanti, Sara, additional, Rossi, Maura, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Libertini, Michela, additional, Provenzano, Salvatore, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Filetti, Marco, additional, Tucci, Marco, additional, Berardi, Rossana, additional, Cantini, Luca, additional, Paoloni, Francesco, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, and Tagliamento, Marco, additional
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- 2023
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14. Supplementary Figure 2 from Enhanced Immune Recognition of Cryptic Glycan Markers in Human Tumors
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Newsom-Davis, Thomas E., primary, Wang, Denong, primary, Steinman, Lawrence, primary, Chen, Paul F-T., primary, Wang, Lai-Xi, primary, Simon, A. Katharina, primary, and Screaton, Gavin R., primary
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- 2023
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15. Data from Enhanced Immune Recognition of Cryptic Glycan Markers in Human Tumors
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Newsom-Davis, Thomas E., primary, Wang, Denong, primary, Steinman, Lawrence, primary, Chen, Paul F-T., primary, Wang, Lai-Xi, primary, Simon, A. Katharina, primary, and Screaton, Gavin R., primary
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- 2023
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16. Supplementary Figure 1 from Enhanced Immune Recognition of Cryptic Glycan Markers in Human Tumors
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Newsom-Davis, Thomas E., primary, Wang, Denong, primary, Steinman, Lawrence, primary, Chen, Paul F-T., primary, Wang, Lai-Xi, primary, Simon, A. Katharina, primary, and Screaton, Gavin R., primary
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- 2023
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17. Cancer immunotherapy and the management of side effects
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Mahalingam, Preethika, primary and Newsom-Davis, Thomas, additional
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- 2023
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18. 512 Time-of-day of pembrolizumab infusion and clinical outcomes of patients with NSCLC: too soon to promote morning infusions
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Cortellini, Alessio, primary, Barrichello, Adriana, additional, Alessi, Joao Victor, additional, Ricciuti, Biagio, additional, Vatz, Victor, additional, Newsom-Davis, Thomas, additional, Evans, Joanne, additional, Lamberti, Giuseppe, additional, Pecci, Federica, additional, Viola, Patrizia, additional, D'Alessio, Antonio, additional, Fulgenzi, Claudia, additional, Awad, Mark, additional, and Pinato, David, additional
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- 2022
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19. Final results from TAIL: updated long-term efficacy of atezolizumab in a diverse population of patients with previously treated advanced non-small cell lung cancer
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Ardizzoni, Andrea, primary, Azevedo, Sergio, additional, Rubio-Viqueira, Belen, additional, Rodriguez-Abreu, Delvys, additional, Alatorre-Alexander, Jorge, additional, Smit, Hans J M, additional, Yu, Jinming, additional, Syrigos, Konstantinos, additional, Höglander, Elen, additional, Kaul, Monika, additional, Tolson, Jonathan, additional, Hu, Youyou, additional, Vollan, Hans Kristian, additional, and Newsom-Davis, Thomas, additional
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- 2022
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20. Regression of Paraneoplastic Rash after Lung Cancer Chemotherapy
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Pinato, David J. and Newsom-Davis, Thomas
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- 2018
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21. Vaccination against SARS-CoV-2 protects from morbidity, mortality and sequelae from COVID19 in patients with cancer
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Pinato, David J., primary, Ferrante, Daniela, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Salazar, Ramon, additional, Mirallas, Oriol, additional, Sureda, Anna, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, Lee, Alvin J.X., additional, Sng, Christopher C.T., additional, Liñan, Raquel, additional, Rossi, Sabrina, additional, Carmona-García, M.Carmen, additional, Sharkey, Rachel, additional, Eremiev, Simeon, additional, Rizzo, Gianpiero, additional, Bain, Hamish DC., additional, Yu, Tamara, additional, Cruz, Claudia A., additional, Perachino, Marta, additional, Saoudi-Gonzalez, Nadia, additional, Fort-Culillas, Roser, additional, Doonga, Kris, additional, Fox, Laura, additional, Roldán, Elisa, additional, Zoratto, Federica, additional, Gaidano, Gianluca, additional, Ruiz-Camps, Isabel, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Shawe-Taylor, Marianne, additional, Fusco, Vittorio, additional, Martinez-Vila, Clara, additional, Berardi, Rossana, additional, Filetti, Marco, additional, Mazzoni, Francesca, additional, Santoro, Armando, additional, Delfanti, Sara, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Prat, Aleix, additional, Tabernero, Josep, additional, Gennari, Alessandra, additional, Cortellini, Alessio, additional, Pinato, David J., additional, Evans, Joanne S., additional, Swallow, Judith, additional, Hanbury, Georgina, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Lee, Alvin JX., additional, Sng, Christopher CT., additional, Sinclair, Alasdair, additional, Cooper, Lee, additional, Rogers, Lucy, additional, Belessiotis, Katherine, additional, Murphy, Cian, additional, Bawany, Samira, additional, Khalique, Saira, additional, Andaleeb, Ramis, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Dolly, Saorise, additional, Sita-Lumsde, Ailsa, additional, Apthorp, Eleanor, additional, Jones, Eleanor, additional, Van Hemelrijck, Mieke, additional, Moss, Charlotte, additional, Russell, Beth, additional, Diamantis, Nikolaos, additional, Mukherjee, Uma, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Garcia Illescas, David, additional, Saoudi, Nadia, additional, Carmona Garcia, MCarmen, additional, Fort-Culillas, Robert, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Mesia, Ricard, additional, Felip, Eudald, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, D’Avanzo, Francesca, additional, Scotti, Lorenza, additional, Krengly, Marco, additional, Marrari, Andrea, additional, Grosso, Federica, additional, Maconi, Antonio, additional, Betti, Marta, additional, Vincenzi, Bruno, additional, Tonini, Giuseppe, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Fotia, Vittoria, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Libertini, Michela, additional, Bertulli, Rossella, additional, Provenzano, Salvatore, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Giusti, Raffaele, additional, Tucci, Marco, additional, Cantini, Luca, additional, Paoloni, Francesco, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, Pommeret, Fanny, additional, and Colomba, Emeline, additional
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- 2022
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22. Persistence of long-term COVID-19 sequelae in patients with cancer: An analysis from the OnCovid registry
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Cortellini, Alessio, primary, Salazar, Ramon, additional, Gennari, Alessandra, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Lee, Alvin JX., additional, Carmona-García, MCarmen, additional, Newsom-Davis, Thomas, additional, Van Hemelrijck, Mieke, additional, Plaja, Andrea, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Generali, Daniele, additional, Bertulli, Rossella, additional, Diamantis, Nikolaos, additional, Mukherjee, Uma, additional, Rizzo, Gianpiero, additional, Yu, Tamara, additional, Zoratto, Federica, additional, Bruna, Riccardo, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Cantini, Luca, additional, Mazzoni, Francesca, additional, Grosso, Federica, additional, Parisi, Alessandro, additional, Saponara, Maristella, additional, Prat, Aleix, additional, and Pinato, David J., additional
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- 2022
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23. Outcomes of the SARS-CoV-2 omicron (B.1.1.529) variant outbreak among vaccinated and unvaccinated patients with cancer in Europe: results from the retrospective, multicentre, OnCovid registry study
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Pinato, David J, primary, Aguilar-Company, Juan, additional, Ferrante, Daniela, additional, Hanbury, Georgina, additional, Bower, Mark, additional, Salazar, Ramon, additional, Mirallas, Oriol, additional, Sureda, Anna, additional, Plaja, Andrea, additional, Cucurull, Marc, additional, Mesia, Ricard, additional, Townsend, Sarah, additional, Jackson, Amanda, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Handford, Jasmine, additional, Sita-Lumsden, Ailsa, additional, Apthorp, Eleanor, additional, Vincenzi, Bruno, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Maluquer, Clara, additional, Pedrazzoli, Paolo, additional, Biello, Federica, additional, Sinclair, Alasdair, additional, Bawany, Samira, additional, Khalique, Saira, additional, Rossi, Sabrina, additional, Rogers, Lucy, additional, Murphy, Cian, additional, Belessiotis, Katherine, additional, Carmona-García, M Carmen, additional, Sharkey, Rachel, additional, García-Illescas, David, additional, Rizzo, Gianpiero, additional, Perachino, Marta, additional, Saoudi-Gonzalez, Nadia, additional, Doonga, Kris, additional, Fox, Laura, additional, Roldán, Elisa, additional, Gaidano, Gianluca, additional, Ruiz-Camps, Isabel, additional, Bruna, Riccardo, additional, Patriarca, Andrea, additional, Martinez-Vila, Clara, additional, Cantini, Luca, additional, Zambelli, Alberto, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Caliman, Enrico, additional, Santoro, Armando, additional, Grosso, Federica, additional, Parisi, Alessandro, additional, Queirolo, Paola, additional, Aujayeb, Avinash, additional, Rimassa, Lorenza, additional, Prat, Aleix, additional, Tucci, Marco, additional, Libertini, Michela, additional, Grisanti, Salvatore, additional, Mukherjee, Uma, additional, Diamantis, Nikolaos, additional, Fusco, Vittorio, additional, Generali, Daniele, additional, Provenzano, Salvatore, additional, Gennari, Alessandra, additional, Tabernero, Josep, additional, Cortellini, Alessio, additional, Evans, Joanne S, additional, Swallow, Judith, additional, Chung, Chris, additional, Patel, Meera, additional, Dettorre, Gino, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Merry, Eve, additional, Chopra, Neha, additional, Lee, Alvin JX, additional, Sng, Christopher CT, additional, Yu, Tamara, additional, Shawe-Taylor, Marianne, additional, Bain, Hamish DC, additional, Wong, Yien Ning Sophia, additional, Galazi, Myria, additional, Benafif, Sarah, additional, Dileo, Palma, additional, Earnshaw, Irina, additional, Patel, Grisma, additional, Wu, Anjui, additional, Soosaipillai, Gehan, additional, Cooper, Lee, additional, Andaleeb, Ramis, additional, Dolly, Saoirse, additional, Srikandarajah, Krishnie, additional, Jones, Eleanor, additional, Van Hemelrijck, Mieke, additional, Moss, Charlotte, additional, Russell, Beth, additional, Chester, John, additional, Loizidou, Angela, additional, Piccart, Martine, additional, Cruz, Claudia A, additional, Reyes, Roxana, additional, Segui, Elia, additional, Marco-Hernández, Javier, additional, Viladot, Margarita, additional, Eremiev, Simeon, additional, Fort-Culillas, Roser, additional, Garcia, Isabel, additional, Liñan, Raquel, additional, Roqué Lloveras, Ariadna, additional, Harbeck, Nadia, additional, Wuerstlein, Rachel, additional, Henze, Franziska, additional, Mahner, Sven, additional, Felip, Eudald, additional, Pous, Anna, additional, D'Avanzo, Francesca, additional, Scotti, Lorenza, additional, Krengli, Marco, additional, Marrari, Andrea, additional, Delfanti, Sara, additional, Maconi, Antonio, additional, Betti, Marta, additional, Tonini, Giuseppe, additional, Di Fazio, Giuseppina Rita, additional, Tondini, Carlo, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Bertulli, Rossella, additional, Baggi, Alice, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Porzio, Giampiero, additional, Saponara, Maristella, additional, Filetti, Marco, additional, Zoratto, Federica, additional, Paoloni, Francesco, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, Iglesias, Maria, additional, Sanchez de Torre, Ana, additional, Tagliamento, Marco, additional, Colomba, Emeline, additional, and Pommeret, Fanny, additional
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- 2022
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24. Prognostic effect of body mass index in patients with advanced NSCLC treated with chemoimmunotherapy combinations.
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UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, UCL - (SLuc) Service de pneumologie, Cortellini, Alessio, Ricciuti, Biagio, Vaz, Victor R, Soldato, Davide, Alessi, Joao V, Dall'Olio, Filippo G, Banna, Giuseppe L, Muthuramalingam, Sethupathi, Chan, Samuel, Majem, Margarita, Piedra, Aida, Lamberti, Giuseppe, Andrini, Elisa, Addeo, Alfredo, Friedlaender, Alex, Facchinetti, Francesco, Gorría, Teresa, Mezquita, Laura, Hoton, Delphine, Lacroix, Valerie, Aboubakar Nana, Frank, Artingstall, James, Comins, Charles, Di Maio, Massimo, Caglio, Andrea, Cave, Judith, McKenzie, Hayley, Newsom-Davis, Thomas, Evans, Joanne S, Tiseo, Marcello, D'Alessio, Antonio, Fulgenzi, Claudia A M, Besse, Benjamin, Awad, Mark M, Pinato, David J, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, UCL - SSS/IREC/SLUC - Pôle St.-Luc, UCL - (SLuc) Service d'anatomie pathologique, UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique, UCL - (SLuc) Service de pneumologie, Cortellini, Alessio, Ricciuti, Biagio, Vaz, Victor R, Soldato, Davide, Alessi, Joao V, Dall'Olio, Filippo G, Banna, Giuseppe L, Muthuramalingam, Sethupathi, Chan, Samuel, Majem, Margarita, Piedra, Aida, Lamberti, Giuseppe, Andrini, Elisa, Addeo, Alfredo, Friedlaender, Alex, Facchinetti, Francesco, Gorría, Teresa, Mezquita, Laura, Hoton, Delphine, Lacroix, Valerie, Aboubakar Nana, Frank, Artingstall, James, Comins, Charles, Di Maio, Massimo, Caglio, Andrea, Cave, Judith, McKenzie, Hayley, Newsom-Davis, Thomas, Evans, Joanne S, Tiseo, Marcello, D'Alessio, Antonio, Fulgenzi, Claudia A M, Besse, Benjamin, Awad, Mark M, and Pinato, David J
- Abstract
INTRODUCTION: It has been recognized that increasing body mass index (BMI) is associated with improved outcome from immune checkpoint inhibitors (ICIs) in patients with various malignancies including non-small cell lung cancer (NSCLC). However, it is unclear whether baseline BMI may influence outcomes from first-line chemoimmunotherapy combinations. METHODS: In this international multicenter study, we evaluated the association between baseline BMI, progression-free survival (PFS) and overall survival (OS) in a cohort of patients with stage IV NSCLC consecutively treated with first-line chemoimmunotherapy combinations. BMI was categorized according to WHO criteria. Results: Among the 853 included patients, 5.3% were underweight; 46.4% were of normal weight; 33.8% were overweight; and 14.5% were obese. Overweight and obese patients were more likely aged ≥70 years (p=0.00085), never smokers (p<0.0001), with better baseline Eastern Cooperative Oncology Group-Performance Status (p=0.0127), and had lower prevalence of central nervous system (p=0.0002) and liver metastases (p=0.0395). Univariable analyses showed a significant difference in the median OS across underweight (15.5 months), normal weight (14.6 months), overweight (20.9 months), and obese (16.8 months) patients (log-rank: p=0.045, log rank test for trend: p=0.131), while no difference was found with respect to the median PFS (log-rank for trend: p=0.510). Neither OS nor PFS was significantly associated with baseline BMI on multivariable analysis. CONCLUSIONS: In contrast to what was observed in the context of chemotherapy-free ICI-based regimens, baseline BMI does not affect clinical outcomes from chemoimmunotherapy combinations in patients with advanced NSCLC.
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- 2022
25. Persistence of long-term COVID-19 sequelae in patients with cancer:An analysis from the OnCovid registry
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Cortellini, Alessio, Salazar, Ramon, Gennari, Alessandra, Aguilar-Company, Juan, Bower, Mark, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Lee, Alvin JX, Carmona-García, MCarmen C., Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Plaja, Andrea, Zambelli, Alberto, Tondini, Carlo, Generali, Daniele, Bertulli, Rossella, Diamantis, Nikolaos, Mukherjee, Uma, Rizzo, Gianpiero, Yu, Tamara, Zoratto, Federica, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Cantini, Luca, Mazzoni, Francesca, Grosso, Federica, Parisi, Alessandro, Saponara, Maristella, Prat, Aleix, Pinato, David J., Cortellini, Alessio, Salazar, Ramon, Gennari, Alessandra, Aguilar-Company, Juan, Bower, Mark, Bertuzzi, Alexia, Brunet, Joan, Lambertini, Matteo, Maluquer, Clara, Pedrazzoli, Paolo, Lee, Alvin JX, Carmona-García, MCarmen C., Newsom-Davis, Thomas, Van Hemelrijck, Mieke, Plaja, Andrea, Zambelli, Alberto, Tondini, Carlo, Generali, Daniele, Bertulli, Rossella, Diamantis, Nikolaos, Mukherjee, Uma, Rizzo, Gianpiero, Yu, Tamara, Zoratto, Federica, Bruna, Riccardo, Sureda, Anna, Martinez-Vila, Clara, Cantini, Luca, Mazzoni, Francesca, Grosso, Federica, Parisi, Alessandro, Saponara, Maristella, Prat, Aleix, and Pinato, David J.
- Abstract
Introduction: A significant proportion of patients with cancer who recover from Coronavirus Disease 2019 (COVID-19) may experience COVID-19 sequelae in the early post-infection phase, which negatively affect their continuity of care and oncological outcome. The long-term prevalence and clinical impact of the post-COVID-19 syndrome in patients with cancer are largely unknown. Methods: In this study, we describe the time course of COVID-19 sequelae in patients with non-advanced cancers enrolled in the OnCovid registry. Results: Overall, 186 patients were included, with a median observation period of 9.9 months (95%CI:8,8–11.3) post-COVID-19 resolution. After a median interval of 2.3 months post-COVID-19 (interquartile range: 1.4–3.7), 31 patients (16.6%) reported ≥1 sequelae, including respiratory complications (14, 7.6%), fatigue (13, 7.1%), neuro-cognitive sequelae (7, 3.8%). The vast majority of the patients were not vaccinated prior to COVID-19. COVID-19-related sequelae persisted in 9.8% and 8% of patients 6 and 12 months after COVID-19 resolution. Persistence of sequelae at first oncological follow-up was associated with history of complicated COVID-19 (45.2% vs 24.8%, p = 0.0223), irrespective of oncological features at COVID-19 diagnosis. Conclusion: This study confirms for the first time that, in a largely unvaccinated population, post-COVID-19 syndrome can affect a significant proportion of patients with non-advanced cancer who recovered from the acute illness. COVID-19 sequelae may persist up to 12 months in some patients, highlighting the need for dedicated prevention and supportive strategies.
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- 2022
26. COVID-19 vaccination associated lung mass mimicking a primary lung cancer: a novel manifestation
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Ostler, Alexandra, primary, Keogh, Georgina, additional, Sherwood, William, additional, and Newsom-Davis, Thomas, additional
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- 2022
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27. Prognostic effect of body mass index in patients with advanced NSCLC treated with chemoimmunotherapy combinations
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Cortellini, Alessio, primary, Ricciuti, Biagio, additional, Vaz, Victor R, additional, Soldato, Davide, additional, Alessi, Joao V, additional, Dall’Olio, Filippo G, additional, Banna, Giuseppe L, additional, Muthuramalingam, Sethupathi, additional, Chan, Samuel, additional, Majem, Margarita, additional, Piedra, Aida, additional, Lamberti, Giuseppe, additional, Andrini, Elisa, additional, Addeo, Alfredo, additional, Friedlaender, Alex, additional, Facchinetti, Francesco, additional, Gorría, Teresa, additional, Mezquita, Laura, additional, Hoton, Delphine, additional, Valerie, Lacroix, additional, Nana, Frank Aboubakar, additional, Artingstall, James, additional, Comins, Charles, additional, Di Maio, Massimo, additional, Caglio, Andrea, additional, Cave, Judith, additional, McKenzie, Hayley, additional, Newsom-Davis, Thomas, additional, Evans, Joanne S, additional, Tiseo, Marcello, additional, D'Alessio, Antonio, additional, Fulgenzi, Claudia A M, additional, Besse, Benjamin, additional, Awad, Mark M, additional, and Pinato, David J, additional
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- 2022
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28. Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study
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Pinato, David J, primary, Tabernero, Josep, additional, Bower, Mark, additional, Scotti, Lorenza, additional, Patel, Meera, additional, Colomba, Emeline, additional, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Dalla Pria, Alessia, additional, Aguilar-Company, Juan, additional, Ottaviani, Diego, additional, Chowdhury, Amani, additional, Merry, Eve, additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Lambertini, Matteo, additional, Tagliamento, Marco, additional, Pous, Anna, additional, Sita-Lumsden, Ailsa, additional, Srikandarajah, Krishnie, additional, Colomba, Johann, additional, Pommeret, Fanny, additional, Seguí, Elia, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Pedrazzoli, Paolo, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Moss, Charlotte, additional, Evans, Joanne S, additional, Russell, Beth, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Biello, Federica, additional, Bertulli, Rossella, additional, Liñan, Raquel, additional, Rossi, Sabrina, additional, Carmona-García, Maria Carmen, additional, Tondini, Carlo, additional, Fox, Laura, additional, Baggi, Alice, additional, Fotia, Vittoria, additional, Parisi, Alessandro, additional, Porzio, Giampero, additional, Saponara, Maristella, additional, Cruz, Claudia Andrea, additional, García-Illescas, David, additional, Felip, Eudald, additional, Roqué Lloveras, Ariadna, additional, Sharkey, Rachel, additional, Roldán, Elisa, additional, Reyes, Roxana, additional, Earnshaw, Irina, additional, Ferrante, Daniela, additional, Marco-Hernández, Javier, additional, Ruiz-Camps, Isabel, additional, Gaidano, Gianluca, additional, Patriarca, Andrea, additional, Bruna, Riccardo, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Sanchez de Torre, Ana, additional, Cantini, Luca, additional, Filetti, Marco, additional, Rimassa, Lorenza, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Krengli, Marco, additional, Santoro, Armando, additional, Prat, Aleix, additional, Van Hemelrijck, Mieke, additional, Diamantis, Nikolaos, additional, Newsom-Davis, Thomas, additional, Gennari, Alessandra, additional, Cortellini, Alessio, additional, Swallow, Judith, additional, Chung, Chris, additional, Dettorre, Gino, additional, Chopra, Neha, additional, Lee, Alvin JX, additional, Sng, Christopher CT, additional, Wong, Yien Ning Sophia, additional, Galazi, Myria, additional, Benafif, Sarah, additional, Dileo, Palma, additional, Patel, Grisma, additional, Wu, Anjui, additional, Sinclair, Alasdair, additional, Soosaipillai, Gehan, additional, Jones, Eleanor, additional, Jackson, Amanda, additional, Piccart, Martine, additional, Colomba-Blameble, Emeline, additional, Cruz, Claudia A, additional, Segui, Elia, additional, Garcia Illescas, David, additional, Mirallas, Oriol, additional, Carbó, Anna, additional, Garcia, Isabel, additional, Wuerstlein, Rachel, additional, Mesia, Ricard, additional, Maluquer, Clara, additional, D'Avanzo, Francesca, additional, Tonini, Giuseppe, additional, Provenzano, Salvatore, additional, Tovazzi, Valeria, additional, Ficorella, Corrado, additional, Queirolo, Paola, additional, Giusti, Raffaele, additional, Mazzoni, Francesca, additional, Zoratto, Federica, additional, Tucci, Marco, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Bracarda, Sergio, additional, and Iglesias, Maria, additional
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- 2021
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29. Determinants of enhanced vulnerability to COVID-19 in UK cancer patients: a European Study
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Pinato, David J., Scotti, Lorenza, Gennari, Alessandra, Colomba-Blameble, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Galazi, Myria, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Wuerstlein, Rachel, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M. Carmen, Sng, Christopher CT., Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia Andrea, Saoudi-Gonzalez, Nadia, Felip, Eudald, Roqué Lloveras, Ariadna, Lee, Alvin J.X., Newsom-Davis, Thomas, Sharkey, Rachel, Chung, Chris, García-Illescas, David, Reyes, Roxana, Sophia Wong, Yien Ning, Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, Van Hemelrijck, Mieke, Diamantis, Nikolaos, and Cortellini, Alessio
- Subjects
Europe ,SARS-CoV-2 ,COVID-19 ,cancer ,UK ,Mortality ,Original Research - Abstract
Background Despite high contagiousness and rapid spread, SARS-CoV-2 has led to heterogeneous outcomes across affected nations. Within Europe, the United Kingdom (UK) is the most severely affected country, with a death toll in excess of 100.000 as of January 2021. We aimed to compare the national impact of COVID-19 on the risk of death in UK cancer patients versus those in continental Europe (EU). Methods We performed a retrospective analysis of the OnCovid study database, a European registry of cancer patients consecutively diagnosed with COVID-19 in 27 centres from February 27 to September 10, 2020. We analysed case fatality rates and risk of death at 30 days and 6 months stratified by region of origin (UK versus EU). We compared patient characteristics at baseline, including oncological and COVID-19 specific therapy across UK and EU cohorts and evaluated the association of these factors with the risk adverse outcome in multivariable Cox regression models. Findings Compared to EU (n=924), UK patients (n=468) were characterised by higher case fatality rates (40.38% versus 26.5%, p
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- 2021
30. Abstract 701: The acute phase response identifies cancer patients with adverse outcomes from SARS-CoV-2 infection as quantified by the OnCovid Inflammatory Score
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Dettorre, Gino M., primary, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Jackson, Amanda, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Sng, Christopher C., additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Mesia, Ricard, additional, Sita-Lumsden, Ailsa, additional, Seguí, Elia, additional, Biello, Federica, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Seeva, Pavetha, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Maconi, Antonio, additional, Moss, Charlotte, additional, Tabernero, Josep, additional, Russell, Beth, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Ottaviani, Diego, additional, Liñan, Raquel, additional, Marrari, Andrea, additional, Carmona-García, M. Carmen, additional, Chopra, Neha, additional, Tondini, Carlo, additional, Mirallas, Oriol, additional, Tovazzi, Valeria, additional, Fotia, Vittoria, additional, Cruz, Claudia Andrea, additional, Saoudi-Gonzalez, Nadia, additional, Felip, Eudald, additional, Roqué, Ariadna, additional, Lee, Alvin J., additional, Newsom-Davis, Thomas, additional, Patriarca, Andrea, additional, Rimassa, Lorenza, additional, Santoro, Armando, additional, Gennari, Alessandra, additional, Diamantis, Nikolaos, additional, and Pinato, David J., additional
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- 2021
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31. Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study
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Pinato, David J., primary, Scotti, Lorenza, additional, Gennari, Alessandra, additional, Colomba-Blameble, Emeline, additional, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Galazi, Myria, additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Mesia, Ricard, additional, Sita-Lumsden, Ailsa, additional, Colomba, Johann, additional, Pommeret, Fanny, additional, Seguí, Elia, additional, Biello, Federica, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Moss, Charlotte, additional, Evans, Joanne S., additional, Russell, Beth, additional, Wuerstlein, Rachel, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Ottaviani, Diego, additional, Liñan, Raquel, additional, Marrari, Andrea, additional, Carmona-García, M.C., additional, Sng, Christopher. C.T., additional, Tondini, Carlo, additional, Mirallas, Oriol, additional, Tovazzi, Valeria, additional, Fotia, Vittoria, additional, Cruz, Claudia A., additional, Saoudi-Gonzalez, Nadia, additional, Felip, Eudald, additional, R. Lloveras, Ariadna, additional, Lee, Alvin. J.X., additional, Newsom-Davis, Thomas, additional, Sharkey, Rachel, additional, Chung, Chris, additional, García-Illescas, David, additional, Reyes, Roxana, additional, Sophia Wong, Yien N., additional, Ferrante, Daniela, additional, Marco-Hernández, Javier, additional, Ruiz-Camps, Isabel, additional, Gaidano, Gianluca, additional, Patriarca, Andrea, additional, Sureda, Anna, additional, Martinez-Vila, Clara, additional, Sanchez de Torre, Ana, additional, Rimassa, Lorenza, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Krengli, Marco, additional, Santoro, Armando, additional, Prat, Aleix, additional, Tabernero, Josep, additional, V. Hemelrijck, Mieke, additional, Diamantis, Nikolaos, additional, and Cortellini, Alessio, additional
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- 2021
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32. sj-docx-1-tam-10.1177_17588359211053416 ��� Supplemental material for COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry
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Garrig��s, Laia, Saura, Cristina, Martinez-Vila, Clara, Zambelli, Alberto, Bower, Mark, Pistilli, Barbara, Lambertini, Matteo, Ottaviani, Diego, Diamantis, Nikolaos, Lumsden, Ailsa, Pernas, Sonia, Generali, Daniele, Segu��, Elia, Vi��as, Gemma, Felip, Eudald, Sanchez, Ana, Rizzo, Gianpiero, Santoro, Armando, Cortellini, Alessio, Perone, Ylenia, Chester, John, Iglesias, Maria, Betti, Marta, Vincenzi, Bruno, Libertini, Michela, Mazzoni, Francesca, Zoratto, Federica, Berardi, Rossana, Guida, Annalisa, Wuerstlein, Rachel, Loizidou, Angela, Sharkey, Rachel, Aguilar Company, Juan, Matas, Marta, Saggia, Chiara, Chiudinelli, Lorenzo, Colomba-Blameble, Emeline, Galazi, Myria, Mukherjee, Uma, Van Hemelrijck, Mieke, Marin, Mar, Strina, Carla, Prat, Aleix, Pla, Helena, Ciruelos, Eva Maria, Bertuzzi, Alexia, del Mastro, Lucia, Porzio, Giampiero, Newsom-Davis, Thomas, Ruiz, Isabel, Delany, Maria Belen, Krengli, Marco, Fotia, Vittoria, Viansone, Alessandro, Chopra, Neha, Romeo, Margarita, Salazar, Ramon, Perez, Ignacio, d���Avanzo, Francesca, Franchi, Michela, Milani, Manuela, Pommeret, Fanny, Tucci, Marco, Pedrazzoli, Paolo, Harbeck, Nadia, Ferrante, Daniela, Pinato, David J., and Gennari, Alessandra
- Subjects
110203 Respiratory Diseases ,FOS: Clinical medicine ,111702 Aged Health Care ,FOS: Health sciences ,111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified ,111299 Oncology and Carcinogenesis not elsewhere classified - Abstract
Supplemental material, sj-docx-1-tam-10.1177_17588359211053416 for COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry by Laia Garrig��s, Cristina Saura, Clara Martinez-Vila, Alberto Zambelli, Mark Bower, Barbara Pistilli, Matteo Lambertini, Diego Ottaviani, Nikolaos Diamantis, Ailsa Lumsden, Sonia Pernas, Daniele Generali, Elia Segu��, Gemma Vi��as, Eudald Felip, Ana Sanchez, Gianpiero Rizzo, Armando Santoro, Alessio Cortellini, Ylenia Perone, John Chester, Maria Iglesias, Marta Betti, Bruno Vincenzi, Michela Libertini, Francesca Mazzoni, Federica Zoratto, Rossana Berardi, Annalisa Guida, Rachel Wuerstlein, Angela Loizidou, Rachel Sharkey, Juan Aguilar Company, Marta Matas, Chiara Saggia, Lorenzo Chiudinelli, Emeline Colomba-Blameble, Myria Galazi, Uma Mukherjee, Mieke Van Hemelrijck, Mar Marin, Carla Strina, Aleix Prat, Helena Pla, Eva Maria Ciruelos, Alexia Bertuzzi, Lucia del Mastro, Giampiero Porzio, Thomas Newsom-Davis, Isabel Ruiz, Maria Belen Delany, Marco Krengli, Vittoria Fotia, Alessandro Viansone, Neha Chopra, Margarita Romeo, Ramon Salazar, Ignacio Perez, Francesca d���Avanzo, Michela Franchi, Manuela Milani, Fanny Pommeret, Marco Tucci, Paolo Pedrazzoli, Nadia Harbeck, Daniela Ferrante, David J. Pinato and Alessandra Gennari in Therapeutic Advances in Medical Oncology
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- 2021
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33. Is TRAIL the holy grail of cancer therapy?
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Newsom-Davis, Thomas, Prieske, Silvia, and Walczak, Henning
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- 2009
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34. CONTACT-01: A phase III, randomized study of atezolizumab plus cabozantinib versus docetaxel in patients with metastatic non-small cell lung cancer (mNSCLC) previously treated with PD-L1/PD-1 inhibitors and platinum-containing chemotherapy.
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Neal, Joel W., primary, Kundu, Palak, additional, Tanaka, Tomohiro, additional, Enquist, Ida, additional, Patel, Sid, additional, Balestrini, Alessia, additional, Wang, Jin, additional, Newsom-Davis, Thomas, additional, Goto, Yasushi, additional, Pavlakis, Nick, additional, and Kim, Sang-We, additional
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- 2021
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35. COVID-19 Sequelae and the Host Proinflammatory Response: An Analysis From the OnCovid Registry.
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Cortellini, Alessio, Gennari, Alessandra, Pommeret, Fanny, Patel, Grisma, Newsom-Davis, Thomas, Bertuzzi, Alexia, Viladot, Margarita, Aguilar-Company, Juan, Mirallas, Oriol, Felip, Eudald, Lee, Alvin J X, Pria, Alessia Dalla, Sharkey, Rachel, Brunet, Joan, Carmona-García, MCarmen, Chester, John, Mukherjee, Uma, Scotti, Lorenza, Dolly, Saoirse, and Sita-Lumsden, Ailsa
- Abstract
Background: Fifteen percent of patients with cancer experience symptomatic sequelae, which impair post-COVID-19 outcomes. In this study, we investigated whether a proinflammatory status is associated with the development of COVID-19 sequelae.Methods: OnCovid recruited 2795 consecutive patients who were diagnosed with Severe Acute Respiratory Syndrome Coronavirus 2 infection between February 27, 2020, and February 14, 2021. This analysis focused on COVID-19 survivors who underwent a clinical reassessment after the exclusion of patients with hematological malignancies. We evaluated the association of inflammatory markers collected at COVID-19 diagnosis with sequelae, considering the impact of previous systemic anticancer therapy. All statistical tests were 2-sided.Results: Of 1339 eligible patients, 203 experienced at least 1 sequela (15.2%). Median baseline C-reactive protein (CRP; 77.5 mg/L vs 22.2 mg/L, P < .001), lactate dehydrogenase (310 UI/L vs 274 UI/L, P = .03), and the neutrophil to lymphocyte ratio (NLR; 6.0 vs 4.3, P = .001) were statistically significantly higher among patients who experienced sequelae, whereas no association was reported for the platelet to lymphocyte ratio and the OnCovid Inflammatory Score, which includes albumin and lymphocytes. The widest area under the ROC curve (AUC) was reported for baseline CRP (AUC = 0.66, 95% confidence interval [CI]: 0.63 to 0.69), followed by the NLR (AUC = 0.58, 95% CI: 0.55 to 0.61) and lactate dehydrogenase (AUC = 0.57, 95% CI: 0.52 to 0.61). Using a fixed categorical multivariable analysis, high CRP (odds ratio [OR] = 2.56, 95% CI: 1.67 to 3.91) and NLR (OR = 1.45, 95% CI: 1.01 to 2.10) were confirmed to be statistically significantly associated with an increased risk of sequelae. Exposure to chemotherapy was associated with a decreased risk of sequelae (OR = 0.57, 95% CI: 0.36 to 0.91), whereas no associations with immune checkpoint inhibitors, endocrine therapy, and other types of systemic anticancer therapy were found.Conclusions: Although the association between inflammatory status, recent chemotherapy and sequelae warrants further investigation, our findings suggest that a deranged proinflammatory reaction at COVID-19 diagnosis may predict for sequelae development. [ABSTRACT FROM AUTHOR]- Published
- 2022
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36. Abstract S01-03: The acute phase response identifies cancer patients with adverse outcomes from SARS-CoV-2 infection as quantified by the OnCovid Inflammatory Score
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Dettorre, Gino M., primary, Dolly, Saoirse, additional, Loizidou, Angela, additional, Chester, John, additional, Jackson, Amanda, additional, Mukherjee, Uma, additional, Zambelli, Alberto, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Sng, Christopher C. T., additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Mesia, Ricard, additional, Sita-Lumsden, Ailsa, additional, Seguí, Elia, additional, Biello, Federica, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Seeva, Pavetha, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Maconi, Antonio, additional, Moss, Charlotte, additional, Russell, Beth, additional, Tabernero, Josep, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Ottaviani, Diego, additional, Marrari, Andrea, additional, Carmona-García, M. Carmen, additional, Chopra, Neha, additional, Tondini, Carlo, additional, Mirallas, Oriol, additional, Tovazzi, Valeria, additional, Fotia, Vittoria, additional, Cruz, Claudia A., additional, Saoudi-Gonzalez, Nadia, additional, Felip, Eudald, additional, Scotti, Lorenza, additional, Lee, Alvin J. X., additional, Newsom-Davis, Thomas, additional, Patriarca, Andrea, additional, Rimassa, Lorenza, additional, Santoro, Armando, additional, Gennari, Alessandra, additional, Van Hemelrijck, Mieke, additional, Diamantis, Nikolaos, additional, and Pinato, David J., additional
- Published
- 2021
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37. Presenting features and early mortality from SARS-CoV-2 infection in cancer patients during the initial stage of the COVID-19 pandemic in Europe
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Pinato, David J., Lee, Alvin J.X., Biello, Federica, Seguí, Elia, Aguilar-Company, Juan, Carbó, Anna, Bruna, Riccardo, Bower, Mark, Rizzo, Gianpiero, Benafif, Sarah, Carmona, Carme, Chopra, Neha, Cruz, Claudia Andrea, D'avanzo, Francesca, Evans, Joanne S., Galazi, Myria, Garcia-Fructuoso, Isabel, Pria, Alessia D., Newsom-Davis, Thomas, Ottaviani, Diego, Patriarca, Andrea, Reyes, Roxana, Sharkey, Rachel, Sng, Christopher C.T., Wong, Yien Ning Sophia, Ferrante, Daniela, Scotti, Lorenza, Avanzi, Gian Carlo, Bellan, Mattia, Castello, Luigi Mario, Marco-Hernández, Javier, Mollà, Meritxell, Pirisi, Mario, Ruiz-Camps, Isabel, Sainaghi, Pier Paolo, Gaidano, Gianluca, Brunet, Joan, Tabernero, Josep, Prat, Aleix, Gennari, Alessandra, Universitat Autònoma de Barcelona, Pinato, David J., Lee, Alvin J.X., Biello, Federica, Seguí, Elia, Aguilar-Company, Juan, Carbó, Anna, Bruna, Riccardo, Bower, Mark, Rizzo, Gianpiero, Benafif, Sarah, Carmona, Carme, Chopra, Neha, Cruz, Claudia Andrea, D'avanzo, Francesca, Evans, Joanne S., Galazi, Myria, Garcia-Fructuoso, Isabel, Pria, Alessia D., Newsom-Davis, Thomas, Ottaviani, Diego, Patriarca, Andrea, Reyes, Roxana, Sharkey, Rachel, Sng, Christopher C.T., Wong, Yien Ning Sophia, Ferrante, Daniela, Scotti, Lorenza, Avanzi, Gian Carlo, Bellan, Mattia, Castello, Luigi Mario, Marco-Hernández, Javier, Mollà, Meritxell, Pirisi, Mario, Ruiz-Camps, Isabel, Sainaghi, Pier Paolo, Gaidano, Gianluca, Brunet, Joan, Tabernero, Josep, Prat, Aleix, Gennari, Alessandra, and Universitat Autònoma de Barcelona
- Abstract
Funding: D.J.P. is supported by grant funding from the Wellcome Trust Strategic Fund (PS3416) and acknowledges grant support by the Cancer Treatment and Research Trust (CTRT) as well as infrastructural support by the Cancer Research UK Imperial Centre. GG is supported by the AIRC 5 × 1000 Grant, No. 21198, Associazione Italiana per la Ricerca sul Cancro Foundation, Milan, Italy. A.G. is supported by the AIRC IG grant, No. 14230, Associazione Italiana per la Ricerca sul Cancro Foundation, Milan, Italy. A.G., G.G., G.C.A., L.M.C., M.B., P.P.S., M.P. from the University of Piemonte Orientale acknowledge support from the UPO Aging Project., We describe the outcomes in cancer patients during the initial outbreak of the COVID-19 in Europe from the retrospective, multi-center observational OnCovid study. We identified 204 cancer patients from eight centers in the United Kingdom, Italy, and Spain aged > 18 (mean = 69) and diagnosed with COVID-19 between February 26th and April 1st, 2020. A total of 127 (62%) were male, 184 (91%) had a diagnosis of solid malignancy, and 103 (51%) had non-metastatic disease. A total of 161 (79%) had > 1 co-morbidity. A total of 141 (69%) patients had > 1 COVID-19 complication. A total of 36 (19%) were escalated to high-dependency or intensive care. A total of 59 (29%) died, 53 (26%) were discharged, and 92 (45%) were in-hospital survivors. Mortality was higher in patients aged > 65 (36% versus 16%), in those with > 2 co-morbidities (40% versus 18%) and developing > 1 complication from COVID-19 (38% versus 4%, p = 0.004). Multi-variable analyses confirmed age > 65 and > 2 co-morbidities to predict for patient mortality independent of tumor stage, active malignancy, or anticancer therapy. During the early outbreak of SARS-CoV-2 infection in Europe co-morbid burden and advancing age predicted for adverse disease course in cancer patients. The ongoing OnCovid study will allow us to compare risks and outcomes in cancer patients between the initial and later stages of the COVID-19 pandemic.
- Published
- 2020
38. Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective
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Soosaipillai, Gehan, primary, Wu, Anjui, additional, Dettorre, Gino M, additional, Diamantis, Nikolaos, additional, Chester, John, additional, Moss, Charlotte, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Sng, Christopher CT, additional, Salazar, Ramon, additional, Brunet, Joan, additional, Jones, Eleanor, additional, Mesia, Ricard, additional, Jackson, Amanda, additional, Mukherjee, Uma, additional, Sita-Lumsden, Ailsa, additional, Seguí, Elia, additional, Ottaviani, Diego, additional, Carbó, Anna, additional, Benafif, Sarah, additional, Würstlein, Rachel, additional, Carmona, Carme, additional, Chopra, Neha, additional, Cruz, Claudia Andrea, additional, Swallow, Judith, additional, Saoudi, Nadia, additional, Felip, Eudald, additional, Galazi, Myria, additional, Garcia-Fructuoso, Isabel, additional, Lee, Alvin J. X., additional, Newsom-Davis, Thomas, additional, Wong, Yien Ning Sophia, additional, Sureda, Anna, additional, Maluquer, Clara, additional, Ruiz-Camps, Isabel, additional, Cabirta, Alba, additional, Prat, Aleix, additional, Loizidou, Angela, additional, Gennari, Alessandra, additional, Ferrante, Daniela, additional, Tabernero, Josep, additional, Russell, Beth, additional, Van Hemelrijck, Mieke, additional, Dolly, Saoirse, additional, Hulbert-Williams, Nicholas J, additional, Pinato, David J, additional, Mollà, Meritxell, additional, Reyes, Roxana, additional, Marco-Hernández, Javier, additional, Bruna, Riccardo, additional, Biello, Federica, additional, Patriarca, Andrea, additional, Zambelli, Alberto, additional, Tondini, Carlo, additional, Fotia, Vittoria, additional, Chiudinelli, Lorenzo, additional, Franchi, Michela, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Tovazzi, Valeria, additional, Bertuzzi, Alexia, additional, Marrari, Andrea, additional, Seeva, Pavetha, additional, Dileo, Palma, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Maconi, Antonio, additional, Betti, Marta, additional, Provenzano, Salvatore, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Liñan, Raquel, additional, Roqué, Ariadna, additional, Mirallas, Oriol, additional, García-Illescas, David, additional, Scotti, Lorenza, additional, Dalla Pria, Alessia, additional, D’Avanzo, Francesca, additional, Martinez, Maria, additional, Evans, Joanne S, additional, Sharkey, Rachel, additional, Rimassa, Lorenza, additional, Santoro, Armando, additional, Gaidano, Gianluca, additional, and Izuzquiza, Macarena, additional
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- 2021
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39. COVID-19 in breast cancer patients: a subanalysis of the OnCovid registry
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Garrigós, Laia, primary, Saura, Cristina, additional, Martinez-Vila, Clara, additional, Zambelli, Alberto, additional, Bower, Mark, additional, Pistilli, Barbara, additional, Lambertini, Matteo, additional, Ottaviani, Diego, additional, Diamantis, Nikolaos, additional, Lumsden, Ailsa, additional, Pernas, Sonia, additional, Generali, Daniele, additional, Seguí, Elia, additional, Viñas, Gemma, additional, Felip, Eudald, additional, Sanchez, Ana, additional, Rizzo, Gianpiero, additional, Santoro, Armando, additional, Cortellini, Alessio, additional, Perone, Ylenia, additional, Chester, John, additional, Iglesias, Maria, additional, Betti, Marta, additional, Vincenzi, Bruno, additional, Libertini, Michela, additional, Mazzoni, Francesca, additional, Zoratto, Federica, additional, Berardi, Rossana, additional, Guida, Annalisa, additional, Wuerstlein, Rachel, additional, Loizidou, Angela, additional, Sharkey, Rachel, additional, Aguilar Company, Juan, additional, Matas, Marta, additional, Saggia, Chiara, additional, Chiudinelli, Lorenzo, additional, Colomba-Blameble, Emeline, additional, Galazi, Myria, additional, Mukherjee, Uma, additional, Van Hemelrijck, Mieke, additional, Marin, Mar, additional, Strina, Carla, additional, Prat, Aleix, additional, Pla, Helena, additional, Ciruelos, Eva Maria, additional, Bertuzzi, Alexia, additional, del Mastro, Lucia, additional, Porzio, Giampiero, additional, Newsom-Davis, Thomas, additional, Ruiz, Isabel, additional, Delany, Maria Belen, additional, Krengli, Marco, additional, Fotia, Vittoria, additional, Viansone, Alessandro, additional, Chopra, Neha, additional, Romeo, Margarita, additional, Salazar, Ramon, additional, Perez, Ignacio, additional, d’Avanzo, Francesca, additional, Franchi, Michela, additional, Milani, Manuela, additional, Pommeret, Fanny, additional, Tucci, Marco, additional, Pedrazzoli, Paolo, additional, Harbeck, Nadia, additional, Ferrante, Daniela, additional, Pinato, David J., additional, and Gennari, Alessandra, additional
- Published
- 2021
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40. Novel cancer therapies: treatments driven by tumour biology
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Ramaswami, Ramya, Harding, Victoria, and Newsom-Davis, Thomas
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- 2013
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41. List of Contributors
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Abayasekara, Robert, primary, Agrawal, Priya, additional, Amer, Saad A, additional, Amso, Nazar N, additional, Anderson, Richard A, additional, Anwar, M Suhail, additional, Balega, Janos, additional, Balen, Adam, additional, Barth, Julian, additional, Bewley, Susan, additional, Bhattacharya, Siladitya, additional, Bombieri, L, additional, Bourne, Tom, additional, Brogan, Kirstyn, additional, Buckett, William M, additional, Cameron, Helen Margaret, additional, Cardozo, Linda, additional, Carr, Susan V., additional, Casteñón, Alejandra, additional, Chaliha, Charlotte, additional, Chandru, Sungathi, additional, Coomarasamy, Arri, additional, Cosgrove, David, additional, Critchley, Hilary O.D., additional, Cuzick, Jack, additional, deSouza, Nandita, additional, Doktoru, Ovrang Djahanbakhch Tip, additional, Downey, Gabrielle, additional, Doumouchtsis, Stergios K., additional, Edmonds, D Keith, additional, Mahdi, Essam El, additional, Farthing, Alan, additional, Fernando, Indrajit, additional, Fish, Julie, additional, Freeman, Robert, additional, Fynes, Michelle M, additional, Ganesan, Raji, additional, Gayther, Simon, additional, Glasier, Anna F, additional, Gore, Martin, additional, Griffiths, Anthony, additional, Grudzinskas, Jurgis Gedis, additional, Hamilton, Mark, additional, Hay, Daniel P, additional, Healy, David L, additional, Hepburn, Mary, additional, Hilton, Paul, additional, Homer, Hayden, additional, Hopkisson, James, additional, Horne, Andrew, additional, Indusekhar, Radha, additional, Irvine, D Stewart, additional, Jacobs, Ian J, additional, Jayaprakasan, Kannamannadiar, additional, Johnson, Margaret A, additional, Jones, Kevin, additional, Josephs, Debra, additional, Kehoe, Sean, additional, Khan, Raheela, additional, Kieran, Eimear P, additional, Konje, Justin C, additional, Lawrence, Alexandra, additional, Lower, Adrian, additional, Luesley, David, additional, Lumsden, Mary Ann, additional, Lynn, John, additional, MacLean, Allan, additional, McIndoe, Angus, additional, Michael, Anthony E, additional, Millar, Michael R, additional, Monga, Ash, additional, Moss, Esther, additional, Munro, Kirsty, additional, Murdoch, Alison, additional, Nelson, Scott McGill, additional, Newsom-Davis, Thomas, additional, Nugent, Karen, additional, Parsons, Matthew, additional, Patwardhan, Asmita, additional, Penketh, Richard J, additional, Phadnis, Saurabh V, additional, Potdar, Neelam, additional, O’Brien, P M Shaughn, additional, Redman, Charles W, additional, Rees, Margaret, additional, Regan, Lesley, additional, Reid, Fiona, additional, Reid, Wendy, additional, Robinson, Dudley, additional, Saridogan, Ertan, additional, Sasieni, Peter, additional, Schünmann, Catherine A, additional, Seckl, Michael J, additional, Sen, Sujan, additional, Shaw, Robert W, additional, Singh, Kavita, additional, Siu, Shing Shun N., additional, Slack, Mark, additional, Smith, Anthony R B, additional, Stanton, Stuart L, additional, Stanway, Susannah, additional, Stewart, Kate P, additional, Stones, William, additional, Sultan, Abdul, additional, Summerville, Karen, additional, Phil,, Sudha S Sundar M, additional, Svensson, William E, additional, Thakar, Ranee, additional, Thiruchelvam, Paul TR, additional, Toozs-Hobson, Philip, additional, Vogiatzi, Maria, additional, Walji, Nawaz, additional, Walsh, Colin A, additional, Weston, Gareth, additional, Widschwendter, Martin, additional, and Zanetto, Ulises, additional
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- 2011
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42. Gestational trophoblastic tumours
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Newsom-Davis, Thomas, primary and Seckl, Michael J., additional
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- 2011
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43. Clinical Portrait of the SARS-CoV-2 Epidemic in European Patients with Cancer
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Pinato, David J., primary, Zambelli, Alberto, additional, Aguilar-Company, Juan, additional, Bower, Mark, additional, Sng, Christopher C.T., additional, Salazar, Ramon, additional, Bertuzzi, Alexia, additional, Brunet, Joan, additional, Mesia, Ricard, additional, Seguí, Elia, additional, Biello, Federica, additional, Generali, Daniele, additional, Grisanti, Salvatore, additional, Rizzo, Gianpiero, additional, Libertini, Michela, additional, Maconi, Antonio, additional, Harbeck, Nadia, additional, Vincenzi, Bruno, additional, Bertulli, Rossella, additional, Ottaviani, Diego, additional, Carbó, Anna, additional, Bruna, Riccardo, additional, Benafif, Sarah, additional, Marrari, Andrea, additional, Wuerstlein, Rachel, additional, Carmona-Garcia, M. Carmen, additional, Chopra, Neha, additional, Tondini, Carlo, additional, Mirallas, Oriol, additional, Tovazzi, Valeria, additional, Betti, Marta, additional, Provenzano, Salvatore, additional, Fotia, Vittoria, additional, Cruz, Claudia Andrea, additional, Dalla Pria, Alessia, additional, D'Avanzo, Francesca, additional, Evans, Joanne S., additional, Saoudi-Gonzalez, Nadia, additional, Felip, Eudald, additional, Galazi, Myria, additional, Garcia-Fructuoso, Isabel, additional, Lee, Alvin J.X., additional, Newsom-Davis, Thomas, additional, Patriarca, Andrea, additional, García-Illescas, David, additional, Reyes, Roxana, additional, Dileo, Palma, additional, Sharkey, Rachel, additional, Wong, Yien Ning Sophia, additional, Ferrante, Daniela, additional, Marco-Hernández, Javier, additional, Sureda, Anna, additional, Maluquer, Clara, additional, Ruiz-Camps, Isabel, additional, Gaidano, Gianluca, additional, Rimassa, Lorenza, additional, Chiudinelli, Lorenzo, additional, Izuzquiza, Macarena, additional, Cabirta, Alba, additional, Franchi, Michela, additional, Santoro, Armando, additional, Prat, Aleix, additional, Tabernero, Josep, additional, Gennari, Alessandra, additional, Avanzi, Gian Carlo, additional, Bellan, Mattia, additional, Castello, Luigi Mario, additional, Martinez, Maria, additional, Mollà, Meritxell, additional, Pirisi, Mario, additional, Scotti, Lorenza, additional, and Swallow, Judith, additional
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- 2020
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44. Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe
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Pinato, David J., primary, Lee, Alvin J. X., additional, Biello, Federica, additional, Seguí, Elia, additional, Aguilar-Company, Juan, additional, Carbó, Anna, additional, Bruna, Riccardo, additional, Bower, Mark, additional, Rizzo, Gianpiero, additional, Benafif, Sarah, additional, Carmona, Carme, additional, Chopra, Neha, additional, Cruz, Claudia Andrea, additional, D’Avanzo, Francesca, additional, Evans, Joanne S., additional, Galazi, Myria, additional, Garcia-Fructuoso, Isabel, additional, Dalla Pria, Alessia, additional, Newsom-Davis, Thomas, additional, Ottaviani, Diego, additional, Patriarca, Andrea, additional, Reyes, Roxana, additional, Sharkey, Rachel, additional, Sng, Christopher C. T., additional, Wong, Yien Ning Sophia, additional, Ferrante, Daniela, additional, Scotti, Lorenza, additional, Avanzi, Gian Carlo, additional, Bellan, Mattia, additional, Castello, Luigi Mario, additional, Marco-Hernández, Javier, additional, Mollà, Meritxell, additional, Pirisi, Mario, additional, Ruiz-Camps, Isabel, additional, Sainaghi, Pier Paolo, additional, Gaidano, Gianluca, additional, Brunet, Joan, additional, Tabernero, Josep, additional, Prat, Aleix, additional, and Gennari, Alessandra, additional
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- 2020
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45. COVID-19 mortality in patients with cancer on chemotherapy or other anticancer treatments: a prospective cohort study
- Author
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Lee, Lennard YW, primary, Cazier, Jean-Baptiste, additional, Angelis, Vasileios, additional, Arnold, Roland, additional, Bisht, Vartika, additional, Campton, Naomi A, additional, Chackathayil, Julia, additional, Cheng, Vinton WT, additional, Curley, Helen M, additional, Fittall, Matthew W, additional, Freeman-Mills, Luke, additional, Gennatas, Spyridon, additional, Goel, Anshita, additional, Hartley, Simon, additional, Hughes, Daniel J, additional, Kerr, David, additional, Lee, Alvin JX, additional, Lee, Rebecca J, additional, McGrath, Sophie E, additional, Middleton, Christopher P, additional, Murugaesu, Nirupa, additional, Newsom-Davis, Thomas, additional, Okines, Alicia FC, additional, Olsson-Brown, Anna C, additional, Palles, Claire, additional, Pan, Yi, additional, Pettengell, Ruth, additional, Powles, Thomas, additional, Protheroe, Emily A, additional, Purshouse, Karin, additional, Sharma-Oates, Archana, additional, Sivakumar, Shivan, additional, Smith, Ashley J, additional, Starkey, Thomas, additional, Turnbull, Chris D, additional, Várnai, Csilla, additional, Yousaf, Nadia, additional, Kerr, Rachel, additional, and Middleton, Gary, additional
- Published
- 2020
- Full Text
- View/download PDF
46. Influence of antibiotic therapy (ATB) on oncological outcomes of metastatic non-small cell lung cancer (mNSCLC) patients treated with chemo-immunotherapy (CIT).
- Author
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Clark, James, primary, Ricciuti, Biagio, additional, Bolina, Anita, additional, Venkatraman, Deepti, additional, Newsom-Davis, Thomas, additional, Ottaviani, Diego, additional, Lee, Karla, additional, Awad, Mark M., additional, and Pinato, David James, additional
- Published
- 2020
- Full Text
- View/download PDF
47. Safety and efficacy of atezolizumab (atezo) in patients (pts) with autoimmune disease (AID): Subgroup analysis of the TAIL study.
- Author
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Newsom-Davis, Thomas, primary, Rubio Viqueira, Belen, additional, Rodriguez-Abreu, Delvys, additional, Alatorre-Alexander, Jorge, additional, Smit, Hans J.M., additional, Yu, Jinming, additional, Syrigos, Konstantinos N., additional, Patel, Hina, additional, Tolson, Jonathan, additional, Cardona, Andrés, additional, Vollan, Hans Kristian, additional, Azevedo, Sergio Jobim, additional, Choy, Ernest, additional, and Ardizzoni, Andrea, additional
- Published
- 2020
- Full Text
- View/download PDF
48. Antibiotic Treatment and Immune Checkpoint Inhibitor Therapy in Patients With Cancer—Reply
- Author
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Pinato, David J., primary, Newsom-Davis, Thomas, additional, and Bower, Mark, additional
- Published
- 2020
- Full Text
- View/download PDF
49. Association of Prior Antibiotic Treatment With Survival and Response to Immune Checkpoint Inhibitor Therapy in Patients With Cancer
- Author
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Pinato, David J., primary, Howlett, Sarah, additional, Ottaviani, Diego, additional, Urus, Heather, additional, Patel, Aisha, additional, Mineo, Takashi, additional, Brock, Cathryn, additional, Power, Danielle, additional, Hatcher, Olivia, additional, Falconer, Alison, additional, Ingle, Manasi, additional, Brown, Anna, additional, Gujral, Dorothy, additional, Partridge, Sarah, additional, Sarwar, Naveed, additional, Gonzalez, Michael, additional, Bendle, Maggie, additional, Lewanski, Conrad, additional, Newsom-Davis, Thomas, additional, Allara, Elias, additional, and Bower, Mark, additional
- Published
- 2019
- Full Text
- View/download PDF
50. The promiscuous receptor
- Author
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Newsom-Davis, Thomas E., Kenny, Laura M., Ngan, Sarah, King, Judith, and Waxman, Jonathan
- Published
- 2009
- Full Text
- View/download PDF
Catalog
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