Search

Your search keyword '"Nejla Ozirmak Lermi"' showing total 2 results
Start Over Author "Nejla Ozirmak Lermi"
2 results on '"Nejla Ozirmak Lermi"'

1. Comparative molecular genomic analyses of a spontaneous rhesus macaque model of mismatch repair-deficient colorectal cancer.

Author

Nejla Ozirmak Lermi, Stanton B Gray, Charles M Bowen, Laura Reyes-Uribe, Beth K Dray, Nan Deng, R Alan Harris, Muthuswamy Raveendran, Fernando Benavides, Carolyn L Hodo, Melissa W Taggart, Karen Colbert Maresso, Krishna M Sinha, Jeffrey Rogers, and Eduardo Vilar more...

Subjects
Genetics, QH426-470
Abstract

Colorectal cancer (CRC) remains the third most common cancer in the US with 15% of cases displaying Microsatellite Instability (MSI) secondary to Lynch Syndrome (LS) or somatic hypermethylation of the MLH1 promoter. A cohort of rhesus macaques from our institution developed spontaneous mismatch repair deficient (MMRd) CRC with a notable fraction harboring a pathogenic germline mutation in MLH1 (c.1029C more...

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results