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1,894 results on '"Nantes Université - pôle Sciences et technologie"'

1. Une extension des modèles graphiques de durée pour estimer l'évolution des coûts de maintenance dans le logement résidentiel

Author: Blanchard, Julien, Leray, Philippe, Marandel, Florianne, Piton, Thomas, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and PILGRIM
Subjects: [INFO]Computer Science [cs]
Abstract: International audience; Une extension des modèles graphiques de durée pour estimer l'évolution des coûts de maintenance dans le logement résidentiel
Published: 2023

2. An optimized Quantum circuit representation of Bayesian networks

Author: Fathallah, Walid, Ben Amor, Nahla, Leray, Philippe, Laboratoire de Recherche Opérationnelle de Décision et de Contrôle de Processus (LARODEC), Université de Tunis-ISG de Tunis, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, and Nantes Université (Nantes Univ)
Subjects: [INFO]Computer Science [cs]
Abstract: International audience; An optimized Quantum circuit representation of Bayesian networks
Published: 2023

3. A Boundary Computation Algorithm for the Workspace Evaluation of Continuum Parallel Robots

Author: Zaccaria, Federico, Idá, Edoardo, Briot, Sébastien, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Dipartimento di Scienze dell'Informazione [Bologna] (DISI), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Centre National de la Recherche Scientifique (CNRS), Autonomie des Robots et Maîtrise des interactions avec l’ENvironnement (LS2N - équipe ARMEN), and Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique)
Subjects: Mechanical Engineering, [INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO]
Abstract: In this paper, a new algorithm for the computation of workspace boundaries of continuum parallel robots (CPRs) is proposed. State-of-the-art techniques are mainly based on time-consuming joint-space discretization approaches or task-space discretization algorithms, and only a few approaches are dedicated to the computation of workspace boundaries. The proposed approach for the computation of the workspace boundaries is based on i) a free-space exploration strategy and ii) a boundary reconstruction algorithm. The former is exploited to identify an initial workspace boundary location (exterior, interior boundaries, and holes), while the latter is used to reconstruct the complete boundary surface. Moreover, the algorithm is designed to be employed with CPRs modelling strategies based on general discretization assumptions, in order to increase its applicability for various scopes. Our method is compared with two state-of-the-art algorithms in four case studies to validate the results and to establish its merits and limitations.
Published: 2023

4. Hexagonal Tungsten Bronze H0.25Cs0.25Nb2.5W2.5O14 as a Negative Electrode Material for Li-Ion Batteries

Author: Etienne Le Calvez, Julio César Espinosa-Angeles, Éric Gautron, Éric Quarez, Olivier Crosnier, Thierry Brousse, Institut des Matériaux Jean Rouxel (IMN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - Ecole Polytechnique de l'Université de Nantes (Nantes Univ - EPUN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Réseau sur le stockage électrochimique de l'énergie (RS2E), Aix Marseille Université (AMU)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Collège de France (CdF (institution))-Université de Picardie Jules Verne (UPJV)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Université Grenoble Alpes (UGA)-Nantes Université (Nantes Univ)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), ANR-16-IDEX-0007,NExT (I-SITE),NExT (I-SITE)(2016), and ANR-10-LABX-0076,STORE-EX,Laboratory of excellency for electrochemical energy storage(2010)
Subjects: General Chemical Engineering, Materials Chemistry, [CHIM.MATE]Chemical Sciences/Material chemistry, General Chemistry, [CHIM.OTHE]Chemical Sciences/Other
Abstract: International audience; Oxides derived from the ReO3 structure, such as bronzes or Wadsley-Roth phases, have re-emerged from the past as they offer very attractive properties as negative electrodes for high-power Li-ion batteries. Here, we revisit the hexagonal bronze Cs0.5Nb2.5W2.5O14 and its protonated H0.25Cs0.25Nb2.5W2.5O14 derivative, which was newly obtained after ion exchange. A panel of characterization techniques (HAADF-STEM imaging, EDX mapping, and XRD) revealed a specific cation ordering in the material and a preferential ion exchange in the heptagonal tunnels of this oxide. When used as Li-ion battery electrodes, H0.25Cs0.25Nb2.5W2.5O14 exhibits higher specific capacities as well as better capacity retention at high currents than Cs0.5Nb2.5W2.5O14. The protonated phase provides specific capacities of 132 and 111 mAh center dot g-1 at, respectively, 0.02 and 0.2 A center dot g-1. Kinetic analysis reveals that the good capacity at a high rate is due to favorable diffusion of lithium ions into the tunnels of H0.25Cs0.25Nb2.5W2.5O14. In addition, using in situ XRD, a solid solution mechanism occurring during lithium insertion was proposed, as well as the different lithiation sites of the material.
Published: 2023

5. Total Least Squares in-field Identification for MEMS-based Triaxial Accelerometers

Author: Ducchi, Massimo, Zaccaria, Federico, Briot, Sébastien, Idá, Edoardo, Dipartimento di Scienze dell'Informazione [Bologna] (DISI), Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Centre National de la Recherche Scientifique (CNRS), Autonomie des Robots et Maîtrise des interactions avec l’ENvironnement (LS2N - équipe ARMEN), and Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique)
Subjects: [INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO]
Abstract: International audience
Published: 2023

6. Singularity Conditions of Concentric Tube Robots

Author: Zaccaria, Federico, Idá, Edoardo, Briot, Sébastien, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Centre National de la Recherche Scientifique (CNRS), Autonomie des Robots et Maîtrise des interactions avec l’ENvironnement (LS2N - équipe ARMEN), and Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique)
Subjects: [INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO]
Abstract: International audience
Published: 2023

7. Real-time motion planning for an autonomous mobile robot with wheel-ground adhesion constraint

Author: Gao, Jiuchun, Claveau, Fabien, Pashkevich, Anatol, Chevrel, Philippe, Abdessamed, Ramdane, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Robotique Et Vivant (LS2N - équipe ReV), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Commande, Observation, Diagnostic et Expérimentation (LS2N - équipe CODEx), Chassis Brakes International (Chassis Brakes International), Hitachi Astemo, and Chassis Brake International Funding
Subjects: autonomous mobile robot, dynamic programming, Human-Computer Interaction, wheel-ground adhesion, Hardware and Architecture, Control and Systems Engineering, time-optimal trajectory, real-time motion planning, Software, [SPI.AUTO]Engineering Sciences [physics]/Automatic, Computer Science Applications
Abstract: International audience; The paper proposes a new real-time motion planning technique for an autonomous mobile robot that is able to find a collision-free path and a corresponding time-optimal trajectory while taking into account limits on the actuator capacities and constraints from the wheel-ground adhesion. The proposed technique includes two sub-modules. The first one, an optimal path planner, is based on the discretization of the robot workspace and dynamic programming principle. It allows finding the shortest path in the robot environment to avoid obstacles and reach the robot target. The second one, an optimal trajectory generator, operates with the discretized robot state-space and also employs dynamic programming techniques. It produces a time-optimal motion along the obtained path, which may include numerous regular and singular trajectory sections caused by the simultaneous application of actuator and wheel-ground adhesion constraints. To adapt this technique to real-time implementation, a moving window strategy is presented that allows regularly updating the robot motion profile in a dynamic environment. The advantages of the developed technique and its suitability for real-time control are illustrated by experimental studies implemented on a car-like mobile robot.
Published: 2023

8. A matheuristic for a 2-echelon vehicle routing problem with capacitated satellites and reverse flows

Author: Dorian Dumez, Christian Tilk, Stefan Irnich, Fabien Lehuédé, Katharina Olkis, Olivier Péton, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Chair of Logistics Management, Gutenberg School of Management and Economics, Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), This research was supported by the Agence Nationale de la Recherche (ANR) under grant ANR-17-CE22-0015 and Deutsche Forschungsgemeinschaft (DFG) under grant IR 122/8-1., and ANR-17-CE22-0015,OPUSS,Optimisation de systèmes synchromodaux urbains(2017)
Subjects: Information Systems and Management, General Computer Science, Modeling and Simulation, [INFO.INFO-RO]Computer Science [cs]/Operations Research [cs.RO], Management Science and Operations Research, Industrial and Manufacturing Engineering
Abstract: International audience; Last-mile collection and delivery services often rely on multi-echelon logistic systems with many types of practical spatial, temporal, and resource constraints. We consider three extensions of the basic 2-echelon vehicle routing problem that are of practical interest: First, second-echelon vehicles need to simultaneously deliver and collect goods at customers within their specified time window. Second, first-echelon vehicles are allowed to perform multiple trips during the planning horizon. Third, the intermediate facilities, called satellites, allow temporary storage of goods, but the quantity that can be stored at a time is limited. This paper integrates these complicating features in a single mathematical model. To solve the problem, we design a decomposition-based matheuristic. It employs a reduced and refined mixed-integer programming formulation and two echelon-specific large neighborhood searches (LNS) to produce improving routes for the respective echelon. The most important algorithmic component is the feasibility check of LNS that relies on a sequence of constant-time and low-complexity tests. The final test allows rescheduling of the operations taking place at a satellite. It adapts the double-justification algorithm known from the scheduling literature. Extensive computational experiments systematically evaluate the new components of the matheuristic and benchmark it against a recent exact method for a related problem. Moreover, the impact of the main problem features such as the number of satellites and their capacity as well as the integration of forward and reverse flows is analyzed.
Published: 2023

9. Evaluating the scalability of reconfigurable manufacturing systems at the design phase

Author: Audrey Cerqueus, Xavier Delorme, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Laboratoire d'Informatique, de Modélisation et d'Optimisation des Systèmes (LIMOS), Ecole Nationale Supérieure des Mines de St Etienne (ENSM ST-ETIENNE)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Département Génie mathématique et industriel (FAYOL-ENSMSE), Ecole Nationale Supérieure des Mines de St Etienne (ENSM ST-ETIENNE)-Institut Henri Fayol, Institut Henri Fayol (FAYOL-ENSMSE), École des Mines de Saint-Étienne (Mines Saint-Étienne MSE), Institut Mines-Télécom [Paris] (IMT), and ANR-21-CE10-0019,RECONFIDURABLE,Conception et pilotage de systèmes de production reconfigurables et durables(2021)
Subjects: Combinatorial analysis, Strategy and Management, Scalability, Line Balancing, [INFO]Computer Science [cs], Multi-objective indicator, Management Science and Operations Research, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation, Industrial and Manufacturing Engineering, Reconfigurable manufacturing systems
Abstract: International audience; To face market volatility, reconfigurable manufacturing systems (RMS) aim to efficiently and cost-effectively react to changes. We focus on one characteristic of RMS: the scalability (ability to adapt the volume of throughput). In the literature, the only few indicators for scalability are not always formally defined and usually only consider a partial view of scalability. Moreover, most of them are actually more suited for the configuration planning rather than for the design. However, the design of the RMS has a high impact on its scalability. We propose the first combinatorial definition of this problem and a new measure to fully assess the scalability of a system at the design phase. This measure, based on a multi-objective approach, can assess the scalability of single-product manufacturing systems, analysing all configurations that it can implement. We present numerical experiments to compare this indicator with a state-of-the-art scalability indicator and with some classical production line design indicators, and we show that future research should focus on scalability as a specific criterion to optimise during the design of an RMS. In addition, the results obtained allow us to infer some managerial insights on the best levers to use when performing a reconfiguration for scalability purpose.
Published: 2023

10. Impredicative Observational Equality

Author: Loïc Pujet, Nicolas Tabareau, Gallinette : vers une nouvelle génération d'assistant à la preuve (GALLINETTE), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
Subjects: [INFO.INFO-PL]Computer Science [cs]/Programming Languages [cs.PL], Type theory, Rewriting theory, [INFO.INFO-LO]Computer Science [cs]/Logic in Computer Science [cs.LO], Confluence, Safety, Risk, Reliability and Quality, Dependent types, Software, Termination
Abstract: International audience; In dependent type theory, impredicativity is a powerful logical principle that allows the definition of propositions that quantify over arbitrarily large types, potentially resulting in self-referential propositions. Impredicativity can provide a system with increased logical strength and flexibility, but in counterpart it comes with multiple incompatibility results. In particular, Abel and Coquand showed that adding definitional uniqueness of identity proofs (UIP) to the main proof assistants that support impredicative propositions (Coq and Lean) breaks the normalization procedure, and thus the type-checking algorithm. However, it was not known whether this stems from a fundamental incompatibility between UIP and impredicativity or if a more suitable algorithm could decide type-checking for a type theory that supports both. In this paper, we design a theory that handles both UIP and impredicativity by extending the recently introduced observational type theory TTobs with an impredicative universe of definitionally proof-irrelevant types, as initially proposed in the seminal work on observational equality of Altenkirch et al. We prove decidability of conversion for the resulting system, that we call CCobs , by harnessing proof-irrelevance to avoid computing with impredicative proof terms. Additionally, we prove normalization for CCobs in plain Martin-Löf type theory, thereby showing that adding proof-irrelevant impredicativity does not increase the computational content of the theory.
Published: 2023

11. Contextual classification of chatter based on unsupervised machine learning

Author: Wang, Zhiqiang, Ritou, Mathieu, da Cunha, Catherine, Furet, Benoît, Ecole Supérieure d'Ingénieurs Léonard de Vinci (ESILV), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and École Centrale de Nantes (ECN)
Subjects: [SPI]Engineering Sciences [physics], General Earth and Planetary Sciences, General Environmental Science
Abstract: International audience
Published: 2023

12. Differentiated Consistency for Worldwide Gossips

Author: Davide Frey, Achour Mostefaoui, Matthieu Perrin, Pierre-Louis Roman, Francois Taiani, the World Is Distributed Exploring the tension between scale and coordination (WIDE), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-SYSTÈMES LARGE ÉCHELLE (IRISA-D1), Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-Institut National de Recherche en Informatique et en Automatique (Inria)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Institut de Recherche en Informatique et Systèmes Aléatoires (IRISA), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Université de Bretagne Sud (UBS)-École normale supérieure - Rennes (ENS Rennes)-CentraleSupélec-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Gestion de Données Distribuées (LS2N - équipe GDD), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Ecole Polytechnique Fédérale de Lausanne (EPFL), ANR-16-CE25-0005,OBrowser,Applications décentralisées sur navigateurs(2016), and ANR-20-CE25-0002,ByBloS,Au-delà des Blockchains : Modules de construction pour les applications à grande échelle zero-confiance multi-utilisateurs(2020)
Subjects: [INFO.INFO-CR]Computer Science [cs]/Cryptography and Security [cs.CR], Blockchain, Computational Theory and Mathematics, Hardware and Architecture, Signal Processing, Distributed system, Epidemic protocol, [INFO.INFO-DC]Computer Science [cs]/Distributed, Parallel, and Cluster Computing [cs.DC], Eventual consistency
Abstract: International audience; Eventual consistency is a consistency model that favors liveness over safety. It is often used in large-scale distributed systems where models ensuring a stronger safety incur performance that are too low to be deemed practical. Eventual consistency tends to be uniformly applied within a system, but we argue a demand exists for differentiated eventual consistency, e.g. in blockchain systems.We propose UPS to address this demand. UPS is a novel consistency mechanism that works in pair with our novel two-phase epidemic broadcast protocol GPS to offer differentiated eventual consistency and delivery speed. We propose two complementary analyses of the broadcast protocol: a continuous analysis and a discrete analysis based on compartmental models used in epidemiology. Additionally, we propose the formal definition of a scalable consistency metric to measure the consistency trade-off at runtime. We evaluate UPS in two simulated worldwide settings: a one-million-node network and a network emulating that of the Ethereum blockchain. In both settings, UPS reduces inconsistencies experienced by a majority of the nodes and reduces the average message latency for the remaining nodes.
Published: 2023

13. A feature-based survey of Fog modeling languages

Author: Abdelghani Alidra, Hugo Bruneliere, Thomas Ledoux, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Software Stack for Massively Geo-Distributed Infrastructures (STACK), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), NaoMod - Nantes Software Modeling Group (LS2N - équipe NaoMod), Laboratoire des Sciences du Numérique de Nantes (LS2N), Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), and ANR-20-CE25-0017,SeMaFoR,Gestion autonome des ressources dans le Fog computing(2020)
Subjects: Computer Networks and Communications, Hardware and Architecture, Internet of Things, Modeling language, Fog Computing, [INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE], Cloud Computing, Survey, [INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL], Software
Abstract: International audience; Fog Computing is a new paradigm aiming at decentralizing the Cloud by geographically distributing away computation, storage and network resources as well as related services. In order to design, develop, deploy, maintain and evolve Fog systems, languages are required for properly modeling both their entities (e.g., infrastructures, topologies, resources configurations) and their specific features such as the locality concept, QoS constraints applied on resources (e.g., energy, data privacy, latency) and their dependencies, the dynamicity of considered workloads, the heterogeneity of both applications and devices, etc. This paper provides a detailed overview of the current state-of-the-art in terms of Fog modeling languages. We relied on our long-term experience in Cloud Computing and Cloud Modeling to contribute a feature model describing what we believe to be the most important characteristics of Fog modeling languages. We also performed a systematic scientific literature search and selection process to obtain a list of already existing Fog modeling languages. Then, we evaluated and compared these Fog modeling languages according to the characteristics expressed in our feature model. As a result, we discuss in this paper the main capabilities of these Fog modeling languages and propose a corresponding set of open research challenges in this area. We expect the presented work to be helpful to both current and future researchers or engineers working on/with Fog systems, as well as to anybody genuinely interested in Fog Computing or more generally in distributed systems.
Published: 2023

14. Cosserat Rod Modeling of Continuum Robots from Newtonian and Lagrangian Perspectives

Author: Matthias Tummers, Vincent Lebastard, Frédéric Boyer, Jocelyne Troccaz, Benoît Rosa, M. Taha Chikhaoui, Gestes Medico-chirurgicaux Assistés par Ordinateur (TIMC-GMCAO), Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525 (TIMC ), VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Robotique Et Vivant (LS2N - équipe ReV), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie (ICube), École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)-Université de Strasbourg (UNISTRA)-Institut National des Sciences Appliquées - Strasbourg (INSA Strasbourg), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria)-Les Hôpitaux Universitaires de Strasbourg (HUS)-Centre National de la Recherche Scientifique (CNRS)-Matériaux et Nanosciences Grand-Est (MNGE), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), ANR-11-LABX-0004,CAMI,Gestes Médico-Chirurgicaux Assistés par Ordinateur(2011), ANR-19-P3IA-0003,MIAI,MIAI @ Grenoble Alpes(2019), ANR-20-CE33-0001,COSSEROOTS,Théorie Cosserat pour les robots élancés contrôlés en déformation(2020), ANR-10-IAHU-0002,MIX-Surg,Institut de Chirurgie Mini-Invasive guidée par l'Image(2010), and ANR-18-CE19-0012,MACROS,Robots continus multi-actionnés pour la chirugie mini-invasive(2018)
Subjects: Cosserat Beams, Flexible Robots, Control and Systems Engineering, Control, Tendon/Wire Mechanism, Modeling, [INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO], Electrical and Electronic Engineering, Learning for Soft Robots, Computer Science Applications
Abstract: International audience; Cosserat rod theory proved efficient modeling performances in robotics, especially in the context of continuum robots, in the past decade. The implementation of such theory is far from being unique and straightforward. We consider the illustrative example of multi-segment, general routing tendon actuated continuum robots in their nominal static operating regime. This paper details two main approaches based on Cosserat rod modeling, namely the Newtonian and Lagrangian approaches. We provide a walk-through guide regarding theoretical derivations and numerical implementation of both approaches, together with a proof of equivalence. This comparative study is supplemented with novel contributions and extensions of each approach and in-depth discussion of their performances and applicability, as well as highlighting their special features.
Published: 2023

15. The Dial-a-Ride Problem with School Bell Time Adjustment

Author: Samuel Vercraene, Fabien Lehuédé, Thibaud Monteiro, Olivier Péton, Décision et Information pour les Systèmes de Production (DISP), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université Lumière - Lyon 2 (UL2), Institut National des Sciences Appliquées (INSA)-Université de Lyon, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Systèmes Logistiques et de Production (SLP ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique Bretagne-Pays de la Loire (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université Lumière - Lyon 2 (UL2)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), IMT Atlantique (IMT Atlantique), and Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS)
Subjects: healthcare logistics, large neighborhood search, paratransit, matheuristic, [INFO]Computer Science [cs], Transportation, school bell time adjustment, [INFO.INFO-RO]Computer Science [cs]/Operations Research [cs.RO], vehicle routing, dial-a-ride problem, Civil and Structural Engineering
Abstract: In this paper, we study a paratransit application in which children are transported every day from their homes to their special schools or medical-social establishments. To optimize this transportation system, the establishments collaborate to propose a joint transportation plan. We propose a new algorithm to jointly build vehicle routes that visit several establishments and simultaneously set the establishments’ opening hours. This algorithm combines a large neighborhood search, the resolution of a route-based model, and the progressive shrinkage of the planning window. It is applied to a real case from the area of Lyon in France, including 34 schools and 575 heterogeneous users served by a heterogeneous fleet of reconfigurable vehicles. On average, we show that in addition to the 10% of saving that can be expected by sharing vehicle routes between schools, 7% of additional savings can be achieved by school bell adjustment. This cost saving also decreases average user ride times and the number of vehicles required, creating longer routes that are more attractive for driver services. Funding: This work was supported by the European Union through the European Regional Development Fund [Grant RA0012500] and by the French Région Auvergne-Rhône-Alpes through the NOMAd project. Supplemental Material: The online appendices are available at https://doi.org/10.1287/trsc.2022.1160 .
Published: 2023

16. Excited state potential energy surfaces of N-phenylpyrrole upon twisting: reference values and comparison between BSE/GW and TD-DFT

Author: Iryna Knysh, Kelvine Letellier, Ivan Duchemin, Xavier Blase, Denis Jacquemin, Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratory of Atomistic Simulation (LSIM), Modélisation et Exploration des Matériaux (MEM), Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Théorie de la Matière Condensée (NEEL - TMC), Institut Néel (NEEL), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), and ANR-20-CE29-0005,BSE-forces,Géométries dans l'état excité dans le formalisme de Bethe-Salpeter(2020)
Subjects: [PHYS]Physics [physics], [CHIM]Chemical Sciences, General Physics and Astronomy, Physical and Theoretical Chemistry
Abstract: International audience; The puzzling case of the mixing between the charge transfer (CT) and local excited (LE) characters upon twisting of the geometry of N-phenylpyrrole (N-PP) is investigated considering the six low-lying singlet excited states (ES). The theoretical calculations of the potential energy surfaces (PES) have been performed for these states using a Coupled Cluster method accounting for the impact of the contributions from the triples, many-body Green's function GW and Bethe–Salpeter equation (BSE) formalisms, as well as Time-Dependent Density Functional Theory (TD-DFT) using various exchange–correlation functionals. Our findings confirm that the BSE formalism is more reliable than TD-DFT for close-lying ES with mixed CT/LE nature. More specifically, BSE/GW yields a more accurate evolution of the excited state PES than TD-DFT when compared to the reference coupled cluster values. BSE/GW PES curves also show negligible exchange–correlation functional starting point dependency in sharp contrast with their TD-DFT counterparts.
Published: 2023

17. Strong Left-Invertibility and Strong Input-Observability of Nonlinear Time-Delay Systems

Author: Yahao Chen, Malek Ghanes, Jean-Pierre Barbot, École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, and Ecole Nationale Supérieure de l'Electronique et de ses Applications (ENSEA)
Subjects: Control and Optimization, Control and Systems Engineering, [SPI.AUTO]Engineering Sciences [physics]/Automatic
Abstract: International audience
Published: 2023

18. Coordination and thermodynamic properties of aqueous protactinium(<scp>v</scp>) by first-principle calculations

Author: Hanna Oher, Jérémy Delafoulhouze, Eric Renault, Valérie Vallet, Rémi Maurice, Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Physico-Chimie Moléculaire Théorique (PCMT), Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 (PhLAM), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), This work was supported by the Région des Pays de la Loire (RCT-PaPAn project) and by the French National Research Agency (ANR-21-CE29-0027, LABEX CaPPA/ANR-11-LABX-0005-01 and I-SITE ULNE/ANR-16-IDEX-0004 ULNE). HPC resources from CCIPL (Centre de Calcul Intensif des Pays de la Loire) were used., ANR-21-CE29-0027,CHESS,Chimie, spectroscopie et spéciation du protactinium(2021), ANR-16-IDEX-0004,ULNE,ULNE(2016), and ANR-11-LABX-0005,Cappa,Physiques et Chimie de l'Environnement Atmosphérique(2011)
Subjects: Chemical Physics (physics.chem-ph), [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Physics - Chemical Physics, FOS: Physical sciences, General Physics and Astronomy, Physical and Theoretical Chemistry
Abstract: International audience; Protactinium (Z = 91) is a very rare actinide with peculiar physico-chemical properties. Indeed, although one may naively think that it behaves similarly to either thorium or uranium by its position in the periodic table, it may in fact follow its own rules. Because of the quite small energy gap between its valence shells (in particular the 5f and 6d ones) and also the strong influence of relativistic effects on its properties, it is actually a challenging element for theoretical chemists. In this article, we combine experimental information, chemical arguments and standard first-principle calculations, complemented by implicit and explicit solvation, to revisit the stepwise complexation of aqueous protactinium(V) with sulfate and oxalate dianionic ligands (SO42- and C2O42-, respectively). From a methodological viewpoint, we notably conclude that it is necessary to at least saturate the coordination sphere of protactinium(V) to reach converged equilibrium constant values. Furthermore, in the case of single complexations (i.e. with one sulfate or oxalate ligand bound in the bidentate fashion), we show that it is necessary to maintain the coordination of one hydroxyl group, thought of in the [PaO(OH)]^3+ precursor, to obtain coherent complexation constants. Therefore, we predict that this hydroxyl group is maintained in the formation of 1:1 complexes while we confirm that it is withdrawn when coordinating three sulfate or oxalate ligands. Finally, we stress that this work is a first step toward the future use of theoretical predictions to elucidate the enigmatic chemistry of protactinium in solution.
Published: 2023

19. Coordination and thermodynamic properties of aqueous protactinium(V) by computational chemistry techniques

Author: Oher, Hanna, Delafoulhouze, Jeremy, Renault, Eric, Vallet, Valérie, Maurice, Rémi, Institut des Sciences Chimiques de Rennes (ISCR), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Physico-Chimie Moléculaire Théorique (PCMT), Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 (PhLAM), Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), ANR-16-IDEX-0004,ULNE,ULNE(2016), ANR-11-LABX-0005,Cappa,Physiques et Chimie de l'Environnement Atmosphérique(2011), and ANR-21-CE29-0027,CHESS,Chimie, spectroscopie et spéciation du protactinium(2021)
Subjects: [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry
Abstract: International audience
Published: 2023

20. Evaluating Reification with Multi-valued Properties in a Knowledge Graph of Licensed Educational Resources

Author: Kieffer, Manoé, Fakih, Ginwa, Serrano-Alvarado, Patricia, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Gestion de Données Distribuées (LS2N - équipe GDD), Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), LABEX Cominlabs - ANR-10-LABX-07-01, and Projet Cominlabs CLARA
Subjects: Knowledge graph, [INFO.INFO-DB]Computer Science [cs]/Databases [cs.DB], [INFO.INFO-IR]Computer Science [cs]/Information Retrieval [cs.IR], RDF reification, [INFO.INFO-WB]Computer Science [cs]/Web, multi-valued properties, query evaluation, educational resources, [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]
Abstract: International audience; This paper presents the construction of a Knowledge Graph (KG) of Educational Resources (ER), where RDF reification is essential. The ERs are described based on the subjects they cover considering their relevance. RDF reification is used to incorporate this subject’s relevance. Multiple reification models with distinct syntax and performance implications for storage and query processing exist. This study aims to experimentally compare four statement-based reification models with four triplestores to determine the most pertinent choice for our KG. We built four versions of the KG. Each version has a distinct reification model, namely standard reification, singleton properties, named graphs, and RDF-star, which were obtained using RML mappings. Each of the four triplestores (Virtuoso, Jena, Oxigraph, and GraphDB) was setup four times (except for Virtuoso, which does not support RDF-star), and seven different SPARQL queries were experimentally evaluated. This study shows that standard reification and named graphs lead to good performance. It also shows that, in the particular context of the used KG, Virtuoso outperforms Jena, GraphDB, and Oxigraph in most queries. The recent specification of RDF-star and SPARQL-star sheds light on statement-level annotations. The empirical study reported in this paper contributes to the efforts towards the efficient usage of RDF reification. In addition, this paper shares the pipeline of the KG con- struction using standard semantic web technologies.
Published: 2023

21. Condition for periodic attractor in 4-dimensional repressilators

Author: Sun, Honglu, Folschette, Maxime, Magnin, Morgan, Méthodes Formelles pour la Bioinformatique (LS2N - équipe MéForBio), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), BioComputing, Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 (CRIStAL), and Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)-Centrale Lille-Université de Lille-Centre National de la Recherche Scientifique (CNRS)
Subjects: Decision tree, Discrete dynamical system, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], Periodic attractor, Repressilator, Gene regulatory networks
Abstract: One of the key questions about gene regulatory networks is how to predict complex dynamical properties based on the influence graph's topology. Earlier theoretical studies have identified conditions for complex dynamical properties, like multistability or oscillations, based on topological features, like the presence of a positive (negative) feedback loop. This work follows this path and aims to find a sufficient and necessary condition for the existence of a periodic attractor in 4-dimensional (4 genes) repressilators based on a discrete modeling framework under some dynamical assumptions. These networks are extensions of the widely studied 3-dimensional repressilator, which has been used in synthetic biology to produce synthetic oscillations. While other researchers have explored specific extensions of the 3-dimensional repressilator to improve synthetic oscillation control, our work investigates all 4-dimensional networks with only inhibitions. By uncovering new insights about periodic attractors in these small networks, our findings could aid the design of new synthetic oscillations. We search for condition for period attractor in an exhaustive manner with the guide of a decision tree model. Our major contributions include: 1) discovering that, with one exception, the relations between gene regulation thresholds do not impact the existence of periodic attractors in any of the influence graphs considered in this study; 2) identifying a sufficient and necessary condition of simple form for the existence of a periodic attractor when the exception is ignored; 3) identifying new topological features of influence graphs that are necessary for predicting the existence of periodic attractor in 4-dimensional repressilators.
Published: 2023

22. HATS : Un jeu de données intégrant la perception humaine appliquée à l'évaluation des métriques de transcription de la parole

Author: Bañeras-Roux, Thibault, Wottawa, Jane, Rouvier, Mickael, Merlin, Teva, Dufour, Richard, Traitement Automatique du Langage Naturel (LS2N - équipe TALN ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Laboratoire d'Informatique de l'Université du Mans (LIUM), Le Mans Université (UM), Laboratoire Informatique d'Avignon (LIA), Avignon Université (AU)-Centre d'Enseignement et de Recherche en Informatique - CERI, Faculty of Applied Sciences University of West Bohemia Plzeň (Pilsen), NTIS P2 Research Center University of West Bohemia Plzeň (Pilsen), Faculty of Informatics Masaryk University Brno, and ANR-20-CE23-0005,DIETS,Diagnostic automatique des erreurs des systèmes de transcription de parole end-to-end à partir de leur réception par les utilisateurs(2020)
Subjects: evaluation metrics, automatic speech recognition, human perception, [INFO]Computer Science [cs], manual annotation, [INFO.INFO-NE]Computer Science [cs]/Neural and Evolutionary Computing [cs.NE], [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]
Abstract: International audience; Conventionally, Automatic Speech Recognition (ASR) systems are evaluated on their ability to correctly recognize each word contained in a speech signal. In this context, the word error rate (WER) metric is the reference for evaluating speech transcripts. Several studies have shown that this measure is too limited to correctly evaluate an ASR system, which has led to the proposal of other variants of metrics (weighted WER, BERTscore, semantic distance, etc.). However, they remain system-oriented, even when transcripts are intended for humans. In this paper, we firstly present Human Assessed Transcription Side-by-side (HATS), an original French manually annotated data set in terms of human perception of transcription errors produced by various ASR systems. 143 humans were asked to choose the best automatic transcription out of two hypotheses. We investigated the relationship between human preferences and various ASR evaluation metrics, including lexical and embedding-based ones, the latter being those that correlate supposedly the most with human perception.; Traditionnellement, les systèmes de reconnaissance automatique de la parole (RAP) sont évalués sur leur capacité à reconnaître correctement chaque mot contenu dans un signal vocal. Dans ce contexte, la mesure du taux d'erreur-mot est la référence pour évaluer les transcriptions vocales. Plusieurs études ont montré que cette mesure est trop limitée pour évaluer correctement un système de RAP, ce qui a conduit à la proposition d'autres variantes et d'autres métriques. Cependant, toutes ces métriques restent orientées "système'' alors même que les transcriptions sont destinées à des humains. Dans cet article, nous proposons un jeu de données original annoté manuellement en termes de perception humaine des erreurs de transcription produites par divers systèmes de RAP. 143 humains ont été invités à choisir la meilleure transcription automatique entre deux hypothèses. Nous étudions la relation entre les préférences humaines et diverses mesures d'évaluation pour les systèmes de RAP, y compris les mesures lexicales et celles fondées sur les plongements de mots.
Published: 2023

23. A Review of Core Operational Business-IT Alignment

Author: Andre, Pascal, Tamzalit, Dalila, Benjilany, Ali, Bruneliere, Hugo, Vérification pour l'Environnement et le LOgiciel (LS2N - équipe VELO), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), NaoMod - Nantes Software Modeling Group (LS2N - équipe NaoMod), Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
Subjects: Business Process Modelling, [INFO]Computer Science [cs], [INFO.INFO-SE]Computer Science [cs]/Software Engineering [cs.SE], Software Application Modelling, Enterprise Architecture, [INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL], Information Systems, Core Operational Business-IT Alignment
Abstract: International audience; In terms of competitiveness, Business-IT Alignment (BITA) is still a crucial challenge for business leaders and CIOs, especially in the context of Digital Transformation and time-to-market challenges. Core Operational BITA can be seen as a projection of BITA to the Enterprise Information System perimeter, i.e., the operational alignment between the business processes and supporting IT. It is a major source of issues (e.g., strong couplings, maintenance costs, technical debt, slow adaptation). These cause a misalignment and thus contribute to the well-known Business-IT Gap. In this paper, we review the current state of this operational alignment in the context of Enterprise Architecture (EA) i.e. between the Business Process layer and the Application layer. Our analysis focuses on the models used at the Business Process and Application layers, the existing or potential links between these layers, and the use of these links to carry out a core operational alignment and facilitate the detection of potential divergence points. As a result, we notably outline some current limitations, such as modelling disparities, misuse of links between the two layers and an under-coverage of real alignment processes. We also discuss some lessons learned and future challenges, mainly around modelling needs and consistency management between the two considered layers.
Published: 2023

24. Learning a Riemannian manifold for the analysis-synthesis of nonstationary sounds

Author: Han, Han, Lostanlen, Vincent, Lagrange, Mathieu, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Signal, IMage et Son (LS2N - équipe SIMS ), and Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique)
Subjects: [SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph], [INFO.INFO-LG]Computer Science [cs]/Machine Learning [cs.LG], [INFO.INFO-SD]Computer Science [cs]/Sound [cs.SD]
Abstract: International audience; Computer sound matching poses an inverse problem, namely, the identification of resynthesis parameters. Borrowing from the differentiable digital signal processing (DDSP) framework, we propose to automate its resolution by training a deep neural network. In this context, we aim to reach a compromise between the computational efficiency of parametric loss (P-loss) versus the psychoacoustical fidelity of spectral loss. Our approach, named ``perceptual--neural--physical'' (PNP), estimates the Riemannian metric which is associated to the composition between parametric synthesis and time--frequency scattering. By doing so, we locally linearize spectral loss and accelerate convergence. Furthermore, resorting to Tikhonov regularization improves the conditioning of the inverse problem. On an analysis--synthesis task for musical arpeggios, PNP training outperforms state-of-the-art methods P-loss (wav2shape) and STFT-based DDSP, as measured in terms of JTFS-based similarity between reference signal and reconstructed signal.; La transformation de sons par ordinateur pose un problème inverse d'identification des paramètres de resynthèse adéquats. Empruntant au formalisme du traitement du signal différentiable (DDSP), nous proposons d'automatiser sa résolution par entrainement d'un réseau de neurones profond. Dans ce contexte, nous visons un compromis entre l'efficacité computationnelle de la perte paramétrique et la fidélité psychoacoustique de la perte spectrale. Notre approche, baptisée perceptuelle-neuronalephysique (PNP), consiste à estimer la métrique riemannienne associée à la composition entre synthèse paramétrique et diffusion temps-fréquence (JTFS). Ce faisant, nous linéarisons localement la perte spectrale et accélérons la convergence. De plus, le recours à une régularisation de Tikhonov améliore le conditionnement du problème inverse. Par rapport à l'état de l'art (wav2shape et DDSP), et pour une tâche difficile d'analyse-synthèse d'arpège musical, l'entrainement via PNP rapproche le signal reconstruit du signal de référence, d'après une mesure de similarité de timbre fondée sur la JTFS.
Published: 2023

25. Incremental Constrained Clustering by Minimal Weighted Modification

Author: Beauchamp, Aymeric, Dao, Thi-Bich-Hanh, Loudni, Samir, Vrain, Christel, Laboratoire d'Informatique Fondamentale d'Orléans (LIFO), Université d'Orléans (UO)-Institut National des Sciences Appliquées - Centre Val de Loire (INSA CVL), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA), Théorie, Algorithmes et Systèmes en Contraintes (LS2N - équipe TASC ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Groupe de Recherche en Informatique, Image et Instrumentation de Caen (GREYC), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS), Andre Augusto Cire, and Roland H. C. Yap
Subjects: Constrained clustering, Constraint programming, Incremental Clustering, Semi-supervised Clustering, User feedback, [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]
Abstract: International audience; Clustering is a well-known task in Machine Learning that aims at grouping instances according to their similarity. It is unsupervised and therefore difficult to tune without human input. In constrained clustering, subject matter experts (SME) can incorporate knowledge through constraints in the clustering algorithm. Involving an expert results in an incremental process where expert constraints are added on the fly, iteratively.Although satisfying the constraints is crucial, successive partitions should look alike to avoid disturbing the expert. In this paper, we present an incremental constrained clustering framework integrating active query strategies and a constraint programming model to fit the expert's expectations while preserving cluster structure, so that the user can understand the process and apprehend its impact. Our model supports instance and group-level constraints, which can be relaxed. Experiments on reference datasets and a case study related to the analysis of satellite image time series show the relevance of our framework.
Published: 2023

26. A review of reference architectures for digital manufacturing: Classification, applicability and open issues

Author: Jan Kaiser, Duncan McFarlane, Gregory Hawkridge, Pascal André, Paulo Leitão, Institute for Manufacturing Cambridge University Engineering Department, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Vérification pour l'Environnement et le LOgiciel (LS2N - équipe VELO), Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Polytechnic Institute of Bragança (IPB), Kaiser, J [0000-0002-7264-5065], and Apollo - University of Cambridge Repository
Subjects: Applicability, Internet of things, General Computer Science, Industry 4, Cyber–physical systems, Digital manufacturing, Cyber-physical systems, General Engineering, Reference architecture, [INFO]Computer Science [cs], Industry 4.0, [SPI.AUTO]Engineering Sciences [physics]/Automatic
Abstract: The industrial application of digital technologies in manufacturing can result in an increased efficiency of processes and an opportunity to integrate production, logistics and maintenance functions. However, increasingly interconnected manufacturing information means progressively more complex systems. Therefore, there is an ever growing need to provide structure in the design and development of such information systems which is the role of a system architecture. So called ‘reference architectures’ guide the design of system architectures used in particular applications. Reference architectures are models of information functions and their connections that provide a structured template with common terminology. Over the last decades, various reference architectures relevant to digital systems in manufacturing have been proposed. However, industrial applications of these reference architectures are scarce and it is difficult to compare and analyse them due to their various levels of application and different uses. In this study, we review and classify reference architectures used to support digital systems in manufacturing. Contributions of the paper include proposing criteria for a model to be referred to as a ‘reference architecture’, an overview and classification of the different perspectives on reference architectures in the literature, and a guideline to support practitioners, developers and academics in selecting a reference architecture.
Published: 2023

27. An EWMA sign chart for dispersion with exact run length properties

Author: Theodoros Perdikis, Stelios Psarakis, Philippe Castagliola, Vicent Giner-Bosch, Petros E. Maravelakis, Athanasios C. Rakitzis, Department of statistics, AUEB, Athens University of Economics and Business (AUEB), Conception, Pilotage, Surveillance et Supervision des systèmes (LS2N - équipe CPS3), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Universitat Politècnica de València (UPV), and University of Piraeus
Subjects: Statistics and Probability, [STAT]Statistics [stat], Sign statistic, variability, Applied Mathematics, Modeling and Simulation, Markov chain, distribution-free Sign statistic Markov chain EWMA control chart variability, EWMA control chart, Statistics, Probability and Uncertainty, distribution-free
Abstract: The EWMA Sign control chart is a distribution-free scheme used for monitoring shifts in the location parameter during process monitoring. In this work, we propose a modified Phase II EWMA chart based on a general Sign statistic, capable of monitoring shifts in the process variability. Regarding the determination of the proposed chart's in-and out-of-control Run Length properties, Markov chain methods are used in combination with a continuous transformation of the suggested general Sign statistic. Our results show the power of the proposed method regarding the proposed chart's exact Run Length properties and its efficiency in detecting shifts in the process variability.
Published: 2023

28. Timing of dawn chorus in songbirds along an anthropization gradient: a species and community approach

Author: Godet, L., Prampart, Abel, Lostanlen, Vincent, Aumond, Pierre, Littoral, Environnement, Télédétection, Géomatique (LETG - Nantes ), Université de Brest (UBO)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université (Nantes Univ)-Littoral, Environnement, Télédétection, Géomatique UMR 6554 (LETG), Université de Brest (UBO)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut de Géographie et d'Aménagement Régional de l'Université de Nantes (Nantes Univ - IGARUN), Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Institut de Géographie et d'Aménagement Régional de l'Université de Nantes (Nantes Univ - IGARUN), Nantes Université (Nantes Univ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Unité Mixte de Recherche en Acoustique Environnementale (UMRAE ), Centre d'Etudes et d'Expertise sur les Risques, l'Environnement, la Mobilité et l'Aménagement (Cerema)-Université Gustave Eiffel, Fondation de France, and Society for Conservation Biology
Subjects: ALAN, bird, birdsong, [SDE]Environmental Sciences, [SHS.GEO]Humanities and Social Sciences/Geography, landscape
Abstract: International audience; The influence of human activities on bird song has been deeply investigated. However, disentangling the relative influence of different anthropogenic pressures (e.g., artificial lights at night, traffic noise, landscape artificialization), of landscape composition (e.g., surface of natural habitat, landscape richness and diversity) and of biotic conditions (bird abundance, richness and diversity) on bird song is still challenging. On the basis of a field survey conducted on a breeding bird community (37 species) in spring 2022 in France, we disentangle the relative influence of such factors of the timing of bird chorus both at the species and community levels. We find that species react differently to the different factors, with species more sensitive to anthropogenic factors and others to biotic conditions. This leads to an important temporal reassembly in the bird chorus at the community level, which promotes a higher temporal turnover in the most anthropized areas and a higher temporal nestedness in the most natural areas. Human activities are thus not only driving temporal changes in different bird species but also promote a change in the temporal structure of the chorus at the whole community.
Published: 2023

29. Anthropization and bird song in the Loire Estuary, France

Author: Godet, L., Prampart, Abel, Lostanlen, Vincent, Littoral, Environnement, Télédétection, Géomatique (LETG - Nantes ), Université de Brest (UBO)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université (Nantes Univ)-Littoral, Environnement, Télédétection, Géomatique UMR 6554 (LETG), Université de Brest (UBO)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut de Géographie et d'Aménagement Régional de l'Université de Nantes (Nantes Univ - IGARUN), Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Institut de Géographie et d'Aménagement Régional de l'Université de Nantes (Nantes Univ - IGARUN), Nantes Université (Nantes Univ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, and UGI
Subjects: birdsong, alan, traffic noise, naturalness, landscape, [SDE]Environmental Sciences, [SHS.GEO]Humanities and Social Sciences/Geography
Abstract: The timing of bird chorus (i.e. the daily highest period of vocal activity in singing birds) follows a circadian pattern but can be modified by anthropogenic factors, mainly including artificial lights at night (ALAN) and traffic noise. However, the impacts of ALAN and noise are rarely dissociated each other and almost never distinguished from other anthropic pressures. The second shortcoming is that the measurement of the timing of chorus is almost systematically based on the occurrence of the first song(s) of the model species, whereas the temporal pattern of the whole vocal activity is never taken into account. Through the example of the breeding birds in the Loire Estuary (France), we first dissociated the different facets of anthropization (ALAN, traffic noise, and land-use and land cover) through a geomatic approach and we analyzed the temporal pattern of bird vocalization through a method based on the recently developed deep neural network “BirdNET”. If ALAN and traffic noise influence the timing of bird chorus, we also found both that taking either a facet or another of anthropization but also different measures of the temporal pattern of bird chorus (e.g., the median time of all the vocalizations instead of the first songs) reveals different results. We thus propose a conceptual framework to measure different facets of anthropization but also different measures of temporal pattern of bird chorus to better understand the influence of human activities on bird vocalizations.
Published: 2023

30. Architectural evolution style representation model

Author: Kadidiatou, Djibo, Oussalah, Mourad, Konaté, Jacqueline, Université de Bamako, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, and Nantes Université (Nantes Univ)
Subjects: [INFO]Computer Science [cs]
Published: 2023

31. ADM: An agile template for requirements documentation

Author: Khelfat, Hind, Oussalah, Mourad, Azzedine, Chikh, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and Université de Tlemcen
Subjects: [INFO]Computer Science [cs]
Published: 2023

32. Just noticeable difference-aware per-scene bitrate-laddering for adaptive video streaming

Author: Menon, Vignesh V, Zhu, Jingwen, Rajendran, Prajit T, Amirpour, Hadi, Callet, Patrick Le, Timmerer, Christian, Alpen-Adria-Universität Klagenfurt [Klagenfurt, Austria], Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and Université Paris-Saclay
Subjects: FOS: Computer and information sciences, video streaming, Bitrate ladder, per-scene encoding, [INFO]Computer Science [cs], Computer Science - Multimedia, Just Noticeable Difference, Multimedia (cs.MM)
Abstract: In video streaming applications, a fixed set of bitrate-resolution pairs (known as a bitrate ladder) is typically used during the entire streaming session. However, an optimized bitrate ladder per scene may result in (i) decreased storage or delivery costs or/and (ii) increased Quality of Experience. This paper introduces a Just Noticeable Difference (JND)-aware per-scene bitrate ladder prediction scheme (JASLA) for adaptive video-on-demand streaming applications. JASLA predicts jointly optimized resolutions and corresponding constant rate factors (CRFs) using spatial and temporal complexity features for a given set of target bitrates for every scene, which yields an efficient constrained Variable Bitrate encoding. Moreover, bitrate-resolution pairs that yield distortion lower than one JND are eliminated. Experimental results show that, on average, JASLA yields bitrate savings of 34.42% and 42.67% to maintain the same PSNR and VMAF, respectively, compared to the reference HTTP Live Streaming (HLS) bitrate ladder Constant Bitrate encoding using x265 HEVC encoder, where the maximum resolution of streaming is Full HD (1080p). Moreover, a 54.34% average cumulative decrease in storage space is observed., Comment: 2023 IEEE International Conference on Multimedia and Expo (ICME)
Published: 2023

33. Real-time Scheduling and Resource Managementfor Energy Autonomous Sensors

Author: Mohamed Abdulla, Mohamed Irfanulla, Chetto, Maryline, Queudet, Audrey, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-École Centrale de Nantes (ECN)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), and IFAC
Subjects: Energy harvesting, Sensor control system, Real-time scheduling, Resource access protocol, Cobotic systems, [INFO]Computer Science [cs]
Abstract: International audience; Energy autonomous sensors are attracting increasing attention because they have potential to provide monitoring for long-time and continuous measurement in many application areas such as transport and health. Energy harvesting can guarantee energy autonomy also called energy neutrality over long period of time if adequate power management strategies are implemented in sensors. As most of them have to execute multiple time critical tasks which access to shared resources in mutual exclusion, classical scheduling strategies should be revisited to provide efficient energy aware solutions. The ED-H scheduler was proved optimal to guarantee energy neutrality of uniprocessor real-time energy harvesting systems when all the tasks are assumedindependent. In this paper, we propose to refine it and we introduce a new scheduling scheme, namely ED-H/DPCP which is adapted to DPCP, the well-known Dynamic Priority Ceiling Protocol to support resource access control. The paper provides the schedulability analysis attached to ED-H/DPCP. We also discuss the implementation and we present integration of ED-H/DPCP within a cobotic application.
Published: 2023

34. Active disturbance rejection control for a transport equation via a differentiatior

Author: Balogoun, Ismaïla, Marx, Swann, Orlov, Yury, Plestan, Franck, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and Centro de Investigacion Cientifica y de Education Superior de Ensenada [Mexico] (CICESE)
Subjects: Stabilization of PDEs, Transport equation, [MATH.MATH-DS]Mathematics [math]/Dynamical Systems [math.DS], Robust control, Active disturbance rejection control, [SPI.AUTO]Engineering Sciences [physics]/Automatic
Abstract: International audience; This paper deals with the stabilization of a transport equation subject to a boundary disturbance. Our feedback design relies on the so-called strategy called active disturbance rejection control (ADRC). The unknown disturbance is estimated by Levant's differentiator and one of the feature of this differentiator is that it allows to estimate in finite-time the disturbance. We prove the existence of solutions of the closed-loop system and the global asymptotic stability of the closed-loop system. A numerical example is given to illustrate the efficiency of our strategy.
Published: 2023

35. The Role of Global and Local Context in Named Entity Recognition

Author: Amalvy, Arthur, Labatut, Vincent, Dufour, Richard, Laboratoire Informatique d'Avignon (LIA), Avignon Université (AU)-Centre d'Enseignement et de Recherche en Informatique - CERI, Traitement Automatique du Langage Naturel (LS2N - équipe TALN ), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), and Association for Computational Linguistics
Subjects: FOS: Computer and information sciences, Computer Science - Computation and Language, Computation and Language (cs.CL), [INFO.INFO-CL]Computer Science [cs]/Computation and Language [cs.CL]
Abstract: Pre-trained transformer-based models have recently shown great performance when applied to Named Entity Recognition (NER). As the complexity of their self-attention mechanism prevents them from processing long documents at once, these models are usually applied in a sequential fashion. Such an approach unfortunately only incorporates local context and prevents leveraging global document context in long documents such as novels, which might hinder performance. In this article, we explore the impact of global document context, and its relationships with local context. We find that correctly retrieving global document context has a greater impact on performance than only leveraging local context, prompting for further research on how to better retrieve that context., Accepted to ACL2023
Published: 2023

36. Mail sorting optimization: a case study of the French postal company La Poste

Author: Amann, Emmanuelle, Gurevsky, Evgeny, Laurent, Arnaud, Mebarki, Nasser, Conception, Pilotage, Surveillance et Supervision des systèmes (LS2N - équipe CPS3), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), and Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS)
Subjects: [INFO]Computer Science [cs]
Abstract: International audience
Published: 2023

37. NMR metabolite quantification of a synthetic urine sample: an inter-laboratory comparison of processing workflows

Author: Canlet, Cécile, DEBORDE, Catherine, Cahoreau, Edern, da Costa, Grégory, Gautier, Roselyne, Jacob, Daniel, Jousse, Cyril, Lacaze, Mélia, Le Mao, Inès, Martineau, Estelle, Peyriga, Lindsay, Richard, Tristan, Silvestre, Virginie, Traïkia, Mounir, Moing, Annick, Giraudeau, Patrick, ToxAlim (ToxAlim), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-MetaToul, MetaboHUB-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Metatoul AXIOM (E20 ), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-MetaboHUB-Génopole Toulouse Midi-Pyrénées [Auzeville] (GENOTOUL), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-ToxAlim (ToxAlim), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Ecole d'Ingénieurs de Purpan (INP - PURPAN), Biologie du fruit et pathologie (BFP), Université de Bordeaux (UB)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaboHUB-Bordeaux, MetaboHUB, Plateforme Bordeaux Metabolome, Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-MetaboHUB-Bordeaux, MetaboHUB-MetaboHUB, Toulouse Biotechnology Institute (TBI), Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), MetaToul FluxoMet (TBI-MetaToul), Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Toulouse Biotechnology Institute (TBI), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National des Sciences Appliquées - Toulouse (INSA Toulouse), Institut National des Sciences Appliquées (INSA)-Université de Toulouse (UT)-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de Recherche Œnologie [Villenave d'Ornon] (OENO), Université de Bordeaux (UB)-Institut des Sciences de la Vigne et du Vin (ISVV)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), MetaboHUB-Clermont, Plateforme Exploration du Métabolisme (PFEM), MetaboHUB-MetaboHUB-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), CAPACITÉS SAS, Nantes Université (Nantes Univ), Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), MetaboHUB-Grand-Ouest, ANR-11-INBS-0010,METABOHUB,Développement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation(2011), and European Project: 814747,SUMMIT
Subjects: Synthetic urine, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [SDV]Life Sciences [q-bio], Peak integration, Metabolomic profiling, Deconvolution, Quantitative NMR
Abstract: International audience; Introduction Absolute quantification of individual metabolites in complex biological samples is crucial in targeted metabolomic profiling. Objectives An inter-laboratory test was performed to evaluate the impact of the NMR software, peak-area determination method (integration vs. deconvolution) and operator on quantification trueness and precision. Methods A synthetic urine containing 32 compounds was prepared. One site prepared the urine and calibration samples, and performed NMR acquisition. NMR spectra were acquired with two pulse sequences including water suppression used in routine analyses. The pre-processed spectra were sent to the other sites where each operator quantified the metabolites using internal referencing or external calibration, and his/her favourite in-house, open-access or commercial NMR tool. Results For 1D NMR measurements with solvent presaturation during the recovery delay (zgpr), 20 metabolites were successfully quantified by all processing strategies. Some metabolites could not be quantified by some methods. For internal referencing with TSP, only one half of the metabolites were quantified with a trueness below 5%. With peak integration and external calibration, about 90% of the metabolites were quantified with a trueness below 5%. The NMRProcFlow integration module allowed the quantification of several additional metabolites. The number of quantified metabolites and quantification trueness improved for some metabolites with deconvolution tools. Trueness and precision were not significantly different between zgpr- and NOESYpr-based spectra for about 70% of the variables. Conclusion External calibration performed better than TSP internal referencing. Inter-laboratory tests are useful when choosing to better rationalize the choice of quantification tools for NMR-based metabolomic profiling and confirm the value of spectra deconvolution tools.
Published: 2023

38. Measurement of the low-energy antitriton inelastic cross section

Author: Acharya, Shreyasi, Adamova, Dagmar, Adler, Alexander, Aglieri Rinella, Gianluca, Agnello, Michelangelo, Agrawal, Neelima, Ahammed, Zubayer, Ahmad, Shakeel, Ahn, Sang Un, Ahuja, Ishaan, Akindinov, Alexander, Al-turany, Mohammad, Aleksandrov, Dmitry, Alessandro, Bruno, Alfanda, Haidar Mas'ud, Alfaro Molina, Jose Ruben, Ali, Bushra, Alici, Andrea, Alizadehvandchali, Negin, Alkin, Anton, Alme, Johan, Alocco, Giacomo, Alt, Torsten, Altamura, Anna Rita, Altsybeev, Igor, Anaam, Mustafa, Andrei, Cristian, Andronic, Anton, Anguelov, Venelin, Antinori, Federico, Antonioli, Pietro, Apadula, Nicole, Aphecetche, Laurent Bernard, Appelshaeuser, Harald, Arata, Carolina, Arcelli, Silvia, Aresti, Mauro, Arnaldi, Roberta, Martins Campos Almeida Arneiro, Jhoao Gabriel, Arsene, Ionut Cristian, Arslandok, Mesut, Augustinus, Andre, Averbeck, Ralf Peter, Azmi, Mohd Danish, Baba, Hitoshi, Badala, Angela, Bae, Joonsuk, Baek, Yongwook, Bai, Xiaozhi, Bailhache, Raphaelle Marie, Bailung, Yoshini, Balbino, Alessandro, Baldisseri, Alberto, Balis, Bartosz, Banerjee, Debjani, Banoo, Zarina, Barbera, Roberto, Barile, Francesco, Barioglio, Luca, Barlou, Maria, Barnafoldi, Gergely Gabor, Barnby, Lee Stuart, Ramillien Barret, Valerie, Barreto De Oliveira Campos, Leonardo, Bartels, Clara, Barth, Klaus, Bartsch, Esther, Bastid, Nicole, Basu, Sumit, Batigne, Guillaume, Battistini, Daniel, Batyunya, Boris, Bauri, Dibakar, Bazo Alba, Jose Luis, Bearden, Ian Gardner, Beattie, Caitlin, Becht, Pascal, Behera, Debadatta, Belikov, Iouri, Bell Hechavarria, Ailec, Bellini, Francesca, Bellwied, Rene, Belokurova, Svetlana, Bencedi, Gyula, Beole, Stefania Maria, Bercuci, Alexandru, Berdnikov, Yaroslav, Berdnikova, Anastasia, Bergmann, Luisa, Besoiu, Mihaela Gabriela, Betev, Latchezar, Bhaduri, Partha Pratim, Bhasin, Anju, Bhat, Mohammad Asif, Bhattacharjee, Buddhadeb, Bianchi, Livio, Bianchi, Nicola, Bielcik, Jaroslav, Bielcikova, Jana, Biernat, Jacek Bogumil, Bigot, Alexandre Patrick, Bilandzic, Ante, Biro, Gabor, Biswas, Saikat, Bize, Nicolas Luc, Blair, Justin Thomas, Blau, Dmitry, Blidaru, Mihail Bogdan, Bluhme, Nora, Blume, Christoph, Boca, Gianluigi, Bock, Friederike, Bodova, Tea, Bogdanov, Alexey, Boi, Stefano, Bok, Jeongsu, Boldizsar, Laszlo, Bombara, Marek, Bond, Peter Matthew, Bonomi, Germano, Borel, Herve, Borissov, Alexander, Borquez Carcamo, Andres Gerardo, Bossi, Hannah, Botta, Elena, El Mard Bouziani, Youssef, Bratrud, Lars, Braun-munzinger, Peter, Bregant, Marco, Broz, Michal, Bruno, Giuseppe Eugenio, Buckland, Matthew Daniel, Budnikov, Dmitry, Buesching, Henner, Bufalino, Stefania, Buhler, Paul Alois, Burmasov, Nazar, Buthelezi, Edith Zinhle, Bylinkin, Aleksandr, Bysiak, Sebastian Adam, Cai, Mengke, Caines, Helen Louise, Caliva, Alberto, Calvo Villar, Ernesto, Mejia Camacho, Juan Manuel, Camerini, Paolo, De Moraes Canedo, Fabio, Carabas, Mihai, Amatriain Carballo, Aitor, Carnesecchi, Francesca, Caron, Robin Albert Andre, Abranches De Carvalho, Leopoldo, Castillo Castellanos, Javier Ernesto, Catalano, Fabio, Ceballos Sanchez, Cesar, Chakaberia, Irakli, Chakraborty, Pritam, Chandra, Sinjini, Chapeland, Sylvain, Chartier, Marielle, Chattopadhyay, Subhasis, Chattopadhyay, Sukalyan, Garcia Chavez, Tonatiuh, Cheng, Tiantian, Cheshkov, Cvetan Valeriev, Cheynis, Brigitte, Chibante Barroso, Vasco Miguel, Dobrigkeit Chinellato, David, Chizzali, Emma Sophia, Cho, Jaeyoon, Cho, Soyeon, Chochula, Peter, Christakoglou, Panagiotis, Christensen, Christian Holm, Christiansen, Peter, Chujo, Tatsuya, Ciacco, Mario, Cicalo, Corrado, Cindolo, Federico, Ciupek, Michael Rudolf, Clai, Giulia, Colamaria, Fabio Filippo, Colburn, Jonathan Samuel, Colella, Domenico, Colocci, Manuel, Concas, Matteo, Conesa Balbastre, Gustavo, Conesa Del Valle, Zaida, Contin, Giacomo, Contreras Nuno, Jesus Guillermo, Coquet, Maurice Louis, Cortese, Pietro, Cosentino, Mauro Rogerio, Costa, Filippo, Costanza, Susanna, Cot, Corentin, Crkovska, Jana, Crochet, Philippe, Cruz Torres, Reynier, Cui, Pengyao, Dainese, Andrea, Danisch, Meike Charlotte, Danu, Andrea, Das, Prottay, Das, Prottoy, Das, Supriya, Dash, Archita Rani, Dash, Sadhana, Regules Medel, Hector David, De Caro, Annalisa, De Cataldo, Giacinto, De Cuveland, Jan, De Falco, Alessandro, De Gruttola, Daniele, De Marco, Nora, De Martin, Chiara, De Pasquale, Salvatore, Deb, Rohaan, Deb, Suman, Del Grande, Raffaele, Dello Stritto, Luigi, Deng, Wenjing, Dhankher, Preeti, Di Bari, Domenico, Di Mauro, Antonio, Diab, Batoul, Arteche Diaz, Raul, Dietel, Thomas, Ding, Yanchun, Divia, Roberto, Dixit, Dhruv Utpalkumar, Djuvsland, Oeystein, Dmitrieva, Uliana, Dobrin, Alexandru Florin, Donigus, Benjamin, Dubinski, Jan Michal, Dubla, Andrea, Dudi, Sandeep, Dupieux, Pascal, Durkac, Martin, Dzalaiova, Natalia, Eder, Tabea Maria, Ehlers, Raymond James, III, Eisenhut, Florian, Ejima, Ren, Elia, Domenico, Erazmus, Barbara Ewa, Ercolessi, Francesca, Erhardt, Filip, Ersdal, Magnus Rentsch, Espagnon, Bruno, Eulisse, Giulio, Evans, David, Evdokimov, Sergey, Fabbietti, Laura, Faggin, Mattia, Faivre, Julien, Fan, Feng, Fan, Wenqing, Fantoni, Alessandra, Fasel, Markus, Fecchio, Pietro, Feliciello, Alessandro, Feofilov, Grigorii, Fernandez Tellez, Arturo, Ferrandi De Oliveira, Lucas, Bertran Ferrer, Marta, Ferrero, Andrea, Ferrero, Chiara, Ferretti, Alessandro, Feuillard, Victor Jose Gaston, Filova, Vendulka, Finogeev, Dmitry, Fionda, Fiorella, Flor, Fernando Antonio, Flores, Amanda Nicole, Foertsch, Siegfried Valentin, Fokin, Ilya, Fokin, Sergey, Fragiacomo, Enrico, Frajna, Eszter, Fuchs, Ulrich, Funicello, Nicola, Furget, Christophe, Furs, Artur, Fusayasu, Takahiro, Gaardhoeje, Jens Joergen, Gagliardi, Martino, Gago Medina, Alberto Martin, Gahlaut, Tanu, Duarte Galvan, Carlos, Gangadharan, Dhevan Raja, Ganoti, Paraskevi, Garabatos Cuadrado, Jose Maria, Tavira Garcia, Andrea, Alvarado Garcia, Jesus Ricardo, Garcia-solis, Edmundo Javier, Gargiulo, Corrado, Demmich, Katharina, Gasik, Piotr Jan, Gautam, Amrit, De Leone Gay, Maria Beatriz, Germain, Marie, Ghimouz, Abderrahmane, Ghosh, Chandrasekhar, Giacalone, Marco, Giubellino, Paolo, Giubilato, Piero, Glaenzer, Aude Marie Camille, Glassel, Peter, Glimos, Ewa, Goh, Daniel Jia Qin, Gonzalez Sebastian, Victor Luis, Gorgon, Marek Boguslaw, Goswami, Kangkan, Gotovac, Sven, Grabski, Varlen, Graczykowski, Lukasz Kamil, Grecka, Ekaterina, Grelli, Alessandro, Grigoras, Costin, Grigoryev, Vladislav, Grigoryan, Smbat, Grosa, Fabrizio, Grosse-oetringhaus, Jan Fiete, Grosso, Raffaele, Grund, David, Garcia Guardiano, Gabriel, Guernane, Rachid, Guilbaud, Maxime Rene Joseph, Gulbrandsen, Kristjan Herlache, Gundem, Tuba, Gunji, Taku, Guo, Wenda, Gupta, Anik, Gupta, Ramni, Gupta, Rashi, Paisano Guzman, Sergio, Gwizdziel, Katarzyna, Gyulai, Laszlo, Habib, Michael Karim, Hadjidakis, Cynthia Marie, Haider, Fakhar Ul, Hamagaki, Hideki, Hamdi, Abdennacer, Han, Younghoon, Hanley, Brian Gerald, Hannigan, Ryan Patrick, Hansen, Joachim, Haque, Md Rihan, Harris, John William, Harton, Austin Vincent, Hassan, Hadi, Hatzifotiadou, Despina, Hauer, Philip, Havener, Laura Brittany, Heckel, Stefan Thomas, Hellbar, Ernst, Helstrup, Haavard, Hemmer, Marvin, Herman, Tomas, Herrera Corral, Gerardo Antonio, Herrmann, Florian, Herrmann, Sarah Nina Edwige, Hetland, Kristin Fanebust, Heybeck, Benedict, Hillemanns, Hartmut, Hippolyte, Boris, Hoffmann, Felix Willi, Hofman, Bas, Hong, Geun Hee, Horst, Maximilian, Horzyk, Adrian, Hou, Yongzhen, Hristov, Peter Zahariev, Hughes, Charles, Huhn, Patrick, Huhta, Laura Maria, Humanic, Thomas, Hutson, Alek, Hutter, Dirk, Ilkaev, Radiy, Ilyas, Hira, Inaba, Motoi, Innocenti, Gian Michele, Ippolitov, Mikhail, Isakov, Artem, Isidori, Tommaso, Islam, Md Samsul, Ivanov, Marian, Ivanov, Vladimir, Iversen, Kaare Endrup, Jablonski, Miroslaw, Jacak, Barbara, Jacazio, Nicolo, Jacobs, Peter Martin, Jadlovska, Slavka, Jadlovsky, Jan, Jaelani, Syaefudin, Jahnke, Cristiane, Jakubowska, Monika Joanna, Janik, Malgorzata Anna, Janson, Thomas, Jercic, Marko, Ji, Su-jeong, Jia, Shihai, Paz Jimenez, Alom Antonio, Jonas, Florian, Jones, Daniel Matthew, Jowett, John, Jung, Jerome, Jung, Michael, Junique, Antoine Jean-simon, Jusko, Anton, Kabus, Maja Jadwiga, Kaewjai, Jetnipit, Kalinak, Peter, Kalteyer, Annalena Sophie, Kalweit, Alexander Philipp, Kaplin, Vladimir, Karasu Uysal, Ayben, Karatovic, David, Karavichev, Oleg, Karavicheva, Tatiana, Karczmarczyk, Przemyslaw, Karpechev, Evgeny, Kebschull, Udo Wolfgang, Keidel, Ralf, Keijdener, Darius, Keil, Markus, Ketzer, Bernhard Franz, Khade, Swapnesh Santosh, Khan, Ahsan Mehmood, Khan, Shaista, Khanzadeev, Alexei, Kharlov, Yury, Khatun, Anisa, Khuntia, Arvind, Kidson, Miles Brower, Kileng, Bjarte, Kim, Beomkyu, Kim, Chong, Kim, Dong Jo, Kim, Eun Joo, Kim, Jaehyun, Kim, Jinsook, Kim, Jiyoung, Kim, Junlee, Kim, Minjung, Kim, Se Yong, Kim, Taejun, Kimura, Kento, Kirsch, Stefan, Kisel, Ivan, Kiselev, Sergey, Kisiel, Adam Ryszard, Kitowski, Jacek Pawel, Klay, Jennifer Lynn, Klein, Jochen, Klein, Spencer Robert, Klein-boesing, Christian, Kleiner, Matthias, Klemenz, Thomas, Kluge, Alexander, Knospe, Anders Garritt, Kobdaj, Chinorat, Kollegger, Thorsten Sven, Kondratyev, Andrey, Kondratyeva, Natalia, Kondratyuk, Evgeny, Konig, Joshua Leon, Konigstorfer, Stephan Alexander, Konopka, Piotr Jan, Kornakov Van, Georgui, Koryciak, Sebastian Dominik, Kotliarov, Artem, Kovalenko, Vladimir, Kowalski, Marek, Kozhuharov, Venelin Valeriev, Kralik, Ivan, Kravcakova, Adela, Krcal, Lubos, Krivda, Marian, Krizek, Filip, Krizkova Gajdosova, Katarina, Kroesen, Martin, Kruger, Mario, Krupova, Diana Maria, Kryshen, Evgeny, Kucera, Vit, Kuhn, Christian Claude, Kuijer, Paulus Gerardus, Kumaoka, Takuya, Kumar, Deekshit, Kumar, Lokesh, Kumar, Navneet, Kumar, Shyam, Kundu, Sourav, Kurashvili, Podist, Kurepin, Alexander, Kurepin, Alexey, Kuryakin, Alexey, Kushpil, Svetlana, Kweon, Min Jung, Kwon, Youngil, La Pointe, Sarah Louise, La Rocca, Paola, Lakrathok, Anantachai, Lamanna, Massimo, Langoy, Rune, Larionov, Pavel, Laudi, Elisa, Lautner, Lukas, Lavicka, Roman, Lea, Ramona, Lee, Hyungjun, Legrand, Iosif-charles, Legras, Gauthier, Lehrbach, Johannes, Lelek, Tomasz Marcin, Lemmon, Roy Crawford, Leon Monzon, Ildefonso, Lesch, Marcel Markus, Lesser, Ezra Douglas, Levai, Peter, Li, Xiaomei, Li, Xing Long, Lien, Jorgen Andre, Lietava, Roman, Likmeta, Iris, Lim, Bong-hwi, Lim, Sanghoon, Lindenstruth, Volker, Lindner, Amelia, Lippmann, Christian, Liu, Alwina Ruixin, Liu, Donghai, Liu, Jian, Setoue Liveraro, Gianni Shigeru, Lofnes, Ingrid Mckibben, Loizides, Constantinos, Lokos, Sandor, Lomker, Johanna, Loncar, Petra, Lopez Lopez, Jorge Andres, Lopez, Xavier Bernard, Lopez Torres, Ernesto, Lu, Pengzhong, Luhder, Jens Robert, Lunardon, Marcello, Luparello, Grazia, Ma, Yugang, Mager, Magnus, Maire, Antonin, Makariev, Martin Vasilev, Malaev, Mikhail, Malfattore, Giovanni, Malik, Nasir Mehdi, Malik, Qasim Waheed, Malik, Salman Khurshid, Malinina, Liudmila, Mallick, Dukhishyam, Mallick, Neelkamal, Mandaglio, Giuseppe, Mandal, Sushobhan Kumar, Manko, Vladislav, Manso, Franck, Manzari, Vito, Mao, Yaxian, Marcjan, Robert Waclaw, Margagliotti, Giacomo Vito, Margotti, Anselmo, Marin, Ana Maria, Markert, Christina, Martinengo, Paolo, Martinez Hernandez, Mario Ivan, Martinez-garcia, Gines, Martins Palhares, Maria Paula, Masciocchi, Silvia, Masera, Massimo, Masoni, Alberto, Massacrier, Laure Marie, Mastroserio, Annalisa, Matonoha, Oliver, Mattiazzo, Serena, Toledo Matuoka, Paula Fernanda, Matyja, Adam Tomasz, Mayer, Christoph, Lafuente Mazuecos, Antonio, Mazzaschi, Francesco, Mazzilli, Marianna, Mdhluli, Joyful Elma, Mechler, Adrian Florin, Melikyan, Yury, Menchaca-rocha, Arturo Alejandro, Meninno, Elisa, Sasikumar Menon, Anjaly, Meres, Michal, Mhlanga, Sibaliso, Miake, Yasuo, Micheletti, Luca, Migliorin, Lucrezia Camilla, Mihaylov, Dimitar Lubomirov, Mikhaylov, Konstantin, Mishra, Aditya Nath, Miskowiec, Dariusz Czeslaw, Modak, Abhi, Mohanty, Auro Prasad, Mohanty, Bedangadas, Khan, Mohammed Mohisin, Molander, Mikael Andreas, Monira, Shirajum, Moravcova, Zuzana, Mordasini, Cindy, Moreira De Godoy, Denise Aparecida, Morozov, Igor, Morsch, Andreas, Mrnjavac, Teo, Muccifora, Valeria, Muhuri, Sanjib, Mulligan, James Declan, Mulliri, Alice, Gameiro Munhoz, Marcelo, Munzer, Robert Helmut, Murakami, Hikari, Murray, Sean, Musa, Luciano, Musinsky, Jan, Myrcha, Julian Wojciech, Naik, Bharati, Nambrath, Anjali Ila, Nandi, Basanta Kumar, Nania, Rosario, Nappi, Eugenio, Nassirpour, Adrian Fereydon, Nath, Abhishek, Nattrass, Christine, Naydenov, Momchil Nikolaev, Neagu, Alexandra, Negru, Adrian-eduard, Nellen, Lukas, Nepeivoda, Roman, Nese, Sigurd, Neskovic, Gvozden, Nielsen, Borge Svane, Nielsen, Emil Gorm, Nikolaev, Sergey, Nikulin, Sergey, Nikulin, Vladimir, Noferini, Francesco, Noh, Seoyoung, Nomokonov, Petr, Norman, Jaime, Novitzky, Norbert, Nowakowski, Piotr, Nyanin, Alexander, Nystrand, Joakim Ingemar, Ogino, Masanori, Oh, Saehanseul, Ohlson, Alice Elisabeth, Okorokov, Vitaly, Oleniacz, Janusz, Oliveira Da Silva, Antonio Carlos, Oliver, Michael Henry, Onnerstad, Anna, Oppedisano, Chiara, Ortiz Velasquez, Antonio, Otwinowski, Jacek Tomasz, Oya, Motomi, Oyama, Ken, Pachmayer, Yvonne Chiara, Padhan, Sonali, Pagano, Davide, Paic, Guy, Palasciano, Antonio, Panebianco, Stefano, Park, Hanseo, Park, Hyebin, Park, Jonghan, Parkkila, Jasper Elias, Patley, Yash, Patra, Rajendra Nath, Paul, Biswarup, Pei, Hua, Peitzmann, Thomas, Peng, Xinye, Pennisi, Michele, Peresunko, Dmitry Yurevich, Mesa Perez, Guillermo, Pestov, Yury, Petrov, Vitalii, Petrovici, Mihai, Peretti Pezzi, Rafael, Piano, Stefano, Pikna, Miroslav, Pillot, Philippe, Pinazza, Ombretta, Pinsky, Lawrence, Pinto, Chiara, Pisano, Silvia, Ploskon, Mateusz Andrzej, Planinic, Mirko, Pliquett, Fabian, Poghosyan, Martin, Polishchuk, Boris, Politano, Stefano, Poljak, Nikola, Pop, Amalia, Porteboeuf, Sarah Julie, Pozdniakov, Valeriy, Yoval Pozos, Irandheny, Pradhan, Kshitish Kumar, Prasad, Sidharth Kumar, Prasad, Suraj, Preghenella, Roberto, Prino, Francesco, Pruneau, Claude Andre, Pshenichnov, Igor, Puccio, Maximiliano, Pucillo, Sara, Pugelova, Zuzana, Qiu, Shi, Quaglia, Luca, Quishpe Quishpe, Raquel Estefania, Ragoni, Simone, Rakotozafindrabe, Andry Malala, Ramello, Luciano, Rami, Fouad, Rodriguez Ramirez, Saul Anibal, Rancien, Thibaut Albert, Rasa, Marika, Rasanen, Sami Sakari, Rath, Rutuparna, Rauch, Max Philip, Ravasenga, Ivan, Read, Kenneth Francis, Reckziegel, Christian, Redelbach, Andreas Ralph, Redlich, Krzysztof, Reetz, Carolina Anna, Rehman, Attiq Ur, Reidt, Felix, Reme-ness, Haakon Andre, Jakubcinova, Zuzana, Reygers, Klaus Johannes, Riabov, Andrei, Riabov, Viktor, Ricci, Riccardo, Richter, Matthias Rudolph, Riedel, Anton Albert, Riegler, Werner, Ristea, Catalin-lucian, Viqueira Rodriguez, Manuel, Rodriguez Cahuantzi, Mario, Roeed, Ketil, Rogalev, Roman, Rogochaya, Elena, Rogoschinski, Tim Sebastian, Rohr, David Michael, Roehrich, Dieter, Fierro Rojas, Pablo, Rojas Torres, Solangel, Rokita, Przemyslaw Stefan, Romanenko, Gleb, Ronchetti, Federico, Rosano, Antonina, Dominguez Rosas, Edgar, Roslon, Krystian, Rossi, Andrea, Roy, Ankhi, Roy, Subhadeep, Rubini, Nicola, Vazquez Rueda, Omar, Ruggiano, Daniela, Rui, Rinaldo, Russek, Pawel Grzegorz, Russo, Roberto, Rustamov, Anar, Ryabinkin, Evgeny, Ryabov, Yury, Rybicki, Andrzej, Rytkonen, Heidi Maria, Ryu, Jaehyeok, Rzesa, Wioleta, Saarimaki, Oskari Antti Matti, Sadek, Rita, Sadhu, Samrangy, Sadovskiy, Sergey, Saetre, Jon-are, Safarik, Karel, Saha, Pallabi, Saha, Sumit Kumar, Saha, Swati, Sahoo, Baidyanath, Sahoo, Bhagyarathi, Sahoo, Raghunath, Sahoo, Sarita, Sahu, Dushmanta, Sahu, Pradip Kumar, Saini, Jogender, Tropp, Klaudia, Sakai, Shingo, Panikkassery Salvan, Malavika, Sambyal, Sanjeev Singh, Samitz, Daniel, Sanna, Isabella, Badaro Saramela, Thiago, Sarkar, Debojit, Sarkar, Nachiketa, Sarma, Pranjal, Sarritzu, Valerio, Mantovani Sarti, Valentina, Sas, Mike, Schambach, Johann Joachim, Scheid, Horst Sebastian, Schiaua, Claudiu Cornel, Schicker, Rainer Martin, Schmah, Alexander, Schmidt, Christian Joachim, Schmidt, Hans Rudolf, Schmidt, Marten Ole, Schmidt, Martin, Schmidt, Nicolas, Schmier, Austin Robert, Schotter, Romain, Schroter, Alexander, Schukraft, Jurgen, Schweda, Kai Oliver, Scioli, Gilda, Scomparin, Enrico, Seger, Janet Elizabeth, Sekiguchi, Yuko, Sekihata, Daiki, Selina, Mariia, Selyuzhenkov, Ilya, Senyukov, Serhiy, Seo, Jin Joo, Serebryakov, Dmitry, Serksnyte, Laura, Sevcenco, Adrian, Shaba, Tebogo Joyce, Shabetai, Alexandre, Shahoyan, Ruben, Shangaraev, Artem, Sharma, Anjali, Sharma, Binti, Sharma, Deependra, Sharma, Himanshu, Sharma, Meenakshi, Sharma, Samarth, Sharma, Sheetal, Sharma, Upasana, Shatat, Afnan, Sheibani, Oveis, Shigaki, Kenta, Hachiya Shimomura, Maya, Shin, Jaehyuck, Shirinkin, Sergey, Shou, Qiye, Sibiryak, Yury, Siddhanta, Sabyasachi, Siemiarczuk, Teodor, Fiorini Da Silva, Tiago, Silvermyr, David Olle Rickard, Simantathammakul, Tawanchat, Simeonov, Radoslav, Singh, Balwan, Singh, Bhawani, Singh, Kamaljeet, Singh, Ranbir, Singh, Randhir, Singh, Ravindra, Singh, Sweta, Singh, Vivek, Singhal, Vikas, Sarkar - Sinha, Tinku, Sitar, Branislav, Sitta, Mario, Skaali, Bernhard, Skorodumovs, Georgijs, Slupecki, Maciej, Smirnov, Nikolai, Snellings, Raimond, Solheim, Emilie Haugland, Song, Jihye, Songmoolnak, Arnon, Sonnabend, Christian, Soramel, Francesca, Soto-hernandez, Analyce Bella, Spijkers, Rik, Sputowska, Iwona Anna, Staa, Joey, Stachel, Johanna, Stan, Ionel, Steffanic, Patrick John, Stiefelmaier, Stephan Friedrich, Stocco, Diego, Storehaug, Ida, Stratmann, Peter, Strazzi, Sofia, Pliatskas Stylianidis, Christos, Alarcon Do Passo Suaide, Alexandre, Suire, Christophe Pierre, Sukhanov, Mikhail, Suljic, Miljenko, Sultanov, Rishat, Sumberia, Vikash, Sumowidagdo, Suharyo, Swain, Sagarika, Szarka, Imrich, Szymkowski, Maciej, Taghavi, Seyed Farid, Taillepied, Guillaume, Takahashi, Jun, Tambave, Ganesh Jagannath, Tang, Siyu, Tang, Zebo, Tapia Takaki, Daniel Jesus, Tapus, Nicolae, Tarasovicova, Lucia Anna, Tarzila, Madalina-gabriela, Tassielli, Giovanni Francesco, Tauro, Arturo, Tejeda Munoz, Guillermo, Telesca, Adriana, Terlizzi, Livia, Terrevoli, Cristina, Thakur, Sanchari, Thomas, Deepa, Tikhonov, Anatoly, Timmins, Anthony Robert, Tkacik, Milan, Tkacik, Tomas, Toia, Alberica, Tokumoto, Ryoka, Tomohiro, Keisuke, Topilskaya, Nataliya, Toppi, Marco, Tork, Theraa M.A., Valencia Torres, Victor, Torres Ramos, Arianna Grisel, Trifiro, Antonio, Triolo, Andrea Sofia, Tripathy, Sushanta, Tripathy, Tulika, Trogolo, Stefano, Trubnikov, Victor, Trzaska, Wladyslaw Henryk, Trzcinski, Tomasz Piotr, Tumkin, Alexandr, Turrisi, Rosario, Tveter, Trine Spedstad, Ullaland, Kjetil, Ulukutlu, Berkin, Uras, Antonio, Urioni, Marta, Usai, Gianluca, Vala, Martin, Valle, Nicolo, Van Doremalen, Lennart, Van Leeuwen, Marco, Van Veen, Casper Arie, Van Weelden, Roelof Jan Gijs, Vande Vyvre, Pierre, Varga, Dezso, Varga, Zoltan, Vasileiou, Maria, Vasiliev, Andrey, Vazquez Doce, Oton, Vechernin, Vladimir, Vercellin, Ermanno, Vergara Limon, Sergio, Verma, Rahul, Vermunt, Lucas Anne, Vertesi, Robert, Verweij, Marta, Vickovic, Linda, Vilakazi, Zabulon, Villalobos Baillie, Orlando, Villani, Anna, Vino, Gioacchino, Vinogradov, Alexander, Virgili, Tiziano, Virta, Maxim Mikael Olavi, Vislavicius, Vytautas, Vodopyanov, Alexander, Voelkel, Benedikt, Volkl, Martin Andreas, Voloshin, Kirill, Voloshin, Sergey, Volpe, Giacomo, Von Haller, Barthelemy, Vorobyev, Ivan, Vozniuk, Nikita, Vrlakova, Janka, Wan, Jie, Wang, Chunzheng, Wang, Dongfang, Wang, Yuanzhe, Wang, Yubiao, Wegrzynek, Adam Tadeusz, Weiglhofer, Felix Thomas, Wenzel, Sandro Christian, Wessels, Johannes Peter, Weyhmiller, Sierra Lisa, Wiechula, Jens, Wikne, Jon, Wilk, Grzegorz Andrzej, Wilkinson, Jeremy John, Willems, Guido Alexander, Windelband, Bernd Stefan, Winn, Michael Andreas, Wright, Josephina Rae, Wu, Wenya, Wu, Yitao, Xu, Ran, Yadav, Ankur, Yadav, Arun Kumar, Yalcin Kuzu, Serpil, Yamaguchi, Yorito, Yang, Shiming, Yano, Satoshi, Yin, Zhongbao, Yoo, In Kwon, Yoon, Jin Hee, Yu, Hyeonjin, Yuan, Shiming, Yuncu, Alperen, Zaccolo, Valentina, Zampolli, Chiara, Zanone, Federica, Zardoshti, Nima, Zarochentsev, Andrey, Zavada, Petr, Zavyalov, Nikolay, Zhalov, Mikhail, Zhang, Biao, Zhang, Chi, Zhang, Liuyao, Zhang, Song, Zhang, Xiaoming, Zhang, Yifei, Zhang, Zhen, Zhao, Mingrui, Zherebchevskii, Vladimir, Yu, Zhi, Zhou, Daicui, Zhou, You, Zhu, Jianhui, Zhu, Ya, Zugravel, Stefan Cristi, Zurlo, Nicola, Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Laboratoire de physique subatomique et des technologies associées (SUBATECH), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), and ALICE
Subjects: isospin, dependence, nucleus, interaction, nucleon, FOS: Physical sciences, GeV, [PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex], antinucleus, High Energy Physics - Experiment, High Energy Physics - Experiment (hep-ex), ALICE, propagation, GEANT, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], TeV, Nuclear Physics - Experiment, Nuclear Experiment (nucl-ex), Nuclear Experiment
Abstract: In this Letter, the first measurement of the inelastic cross section for antitriton$-$nucleus interactions is reported, covering the momentum range of $0.8 \leq p < 2.4$ GeV/$c$. The measurement is carried out using data recorded with the ALICE detector in pp and Pb$-$Pb collisions at a centre-of-mass energy per nucleon of 13 TeV and 5.02 TeV, respectively. The detector material serves as an absorber for antitriton nuclei. The raw yield of (anti)triton nuclei measured with the ALICE apparatus is compared to the results from detailed ALICE simulations based on the GEANT4 toolkit for the propagation of (anti)particles through matter, allowing one to quantify the inelastic interaction probability in the detector material. This analysis complements the measurement of the inelastic cross section of antinuclei up to $A=3$ carried out by the ALICE Collaboration, and demonstrates the feasibility of the study of the isospin dependence of inelastic interaction cross section with the analysis techniques presented in this Letter., 20 pages, 2 captioned figures, authors from page 14, submitted to PLB, figures at http://alice-publications.web.cern.ch/node/9480
Published: 2023

39. Optimisation du pilotage industriel d'une piscine publique grâce à la modélisation dirigée par les données : proposition d'un jeu de données applicatif

Author: Gauthier-Clerc, François, Le Capitaine, Hoel, Claveau, Fabien, Chevrel, Philippe, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT), AFIA-Association Française pour l'Intelligence Artificielle, ICube-laboratoire des sciences de l'ingénieur, de l'informatique et de l'imagerie, Christelle Launois, and Catherine Roussey
Subjects: Optimisation énergétique, Energy optimization, Machine learning, Dynamic system modeling, Apprentissage automatique Dynamic systems modeling, Modélisation de systèmes dynamiques, [INFO.INFO-AI]Computer Science [cs]/Artificial Intelligence [cs.AI]
Abstract: National audience; This article highlights the importance of data driven models for the modeling and control of dynamic systems. It recommends the use of accurate and consistent models for data-driven control. The study is based on the example of a public swimming pool and demonstrates the difficulties of optimizing a model in a real-world data context. A dataset from a real system and calibrated performance criteria are proposed to improve the techniques of learning and identifying systems for better energy optimization of numerous industrial installations.; Cet article met en évidence l'importance de modèles dirigés par les données pour la modélisation/pilotage de systèmes dynamiques. Il recommande l'utilisation de modèles précis et capable d'extrapolation pour un pilotage générique. L'étude se base sur l'exemple d'une piscine publique et montre les difficultés d'obtenir un bon modèle dans un contexte de données réelles. Un jeu de données issu d'un système réel et des critères de performance sont proposés pour aider à améliorer les techniques d'apprentissage et d'identification en vue d'une meilleure optimisation énergétique de nombreuses installations industrielles.
Published: 2023

40. Etat de l’art sur la co-simulation robotique et réseau des systèmes multi-robots

Author: Balaguer, Théotime, Simonin, Olivier, Lassous, Isabelle, Fantoni, Isabelle, CITI Centre of Innovation in Telecommunications and Integration of services (CITI), Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National de Recherche en Informatique et en Automatique (Inria), Laboratoire de l'Informatique du Parallélisme (LIP), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Agence de l'Innovation de Défense Institut National des Sciences Appliquées, and ANR-20-ASTR-0003,CONCERTO,mobilité Contrôlée et cOmmunicatioNs effiCaces dans une flottE de dRones auTo-Organisée(2020)
Subjects: Communication networks, [INFO.INFO-MA]Computer Science [cs]/Multiagent Systems [cs.MA], Multi-robots systems, Systèmes multi-robots, Cosimulation, Réseaux de communication, [INFO.INFO-RB]Computer Science [cs]/Robotics [cs.RO], Co-simulation, [INFO.INFO-MO]Computer Science [cs]/Modeling and Simulation
Abstract: National audience; Simulation of multi-robots systems require the integration of both the robotic and network components. Leveraging the existing tools from each community seems evident, but merging two completely different simulators proves challenging. This paper presents the state of the art in co-simulators that tackle this problematic, and provide details on the challenges arising when one wants to create an efficient co-simulator.; La simulation de systèmes multi-robots nécessite l'intégration des composantes robotique et réseau au sein d'un même environnement de simulation. La réutilisation des outils existants dans les communautés robotique et réseau semble être une évidence, mais la fusion de deux simulateurs présente des défis structurels qu'il faut surmonter afin d'obtenir une simulation "réaliste" d'un système multi-robots. Dans cet état de l'art, nous présentons les co-simulateurs qui abordent cette problématique et détaillons les défis auxquels il faut répondre pour la conception d'un co-simulateur performant.
Published: 2023

41. Intercalated Organic Redox-active Anions for Enhanced Capacity of Layered Double Hydroxides

Author: Gerlach, Patrick, Douard, Camille, Gaalich, Insaf, Athouël, Laurence, Sarmet, Julien, Leroux, Fabrice, Tavoit-Gueho, Christine, Stevens, Philippe, Toussaint, Gwenaëlle, Brousse, Thierry, Institut des Matériaux Jean Rouxel (IMN), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - Ecole Polytechnique de l'Université de Nantes (Nantes Univ - EPUN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Réseau sur le stockage électrochimique de l'énergie (RS2E), Aix Marseille Université (AMU)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Collège de France (CdF (institution))-Université de Picardie Jules Verne (UPJV)-Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL (ENSCP), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Pau et des Pays de l'Adour (UPPA)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA)-Université Grenoble Alpes (UGA)-Nantes Université (Nantes Univ)-Université de Montpellier (UM)-Ecole Nationale Supérieure de Chimie de Montpellier (ENSCM), Université de Montpellier (UM), Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), Laboratoire des Matériels Électriques (EDF R&D LME), EDF R&D (EDF R&D), EDF (EDF)-EDF (EDF), EDF (EDF), ANR-20-CE05-0024,LaDHy,hydroxydes lamellaires pour systèmes de stockage innovants(2020), and ANR-10-LABX-0076,STORE-EX,Laboratory of excellency for electrochemical energy storage(2010)
Subjects: [CHIM]Chemical Sciences
Abstract: International audience; A Layered Double Hydroxide (LDH) compound LDH ([Mg 2 Al(OH) 6 ] + x 2 H 2 O) intercalated with a redox active organic anion, Anthraquinone-2-sulfonate (AQS), has been envisioned as an electrode material for high power aqueous based battery. The purpose is to use this interlayer redox active molecule for the enhancement of the specific capacity at the LDH composite electrode, which should allow fast charge transfer at the negative electrode for high power storage applications. This is achieved by the reduction of AQS in charge and oxidation in discharge within a redox inactive LDH matrix. The first charge of this new material [Mg 2 Al(OH) 6 ] + [AQSO 3 ] − x 2 H 2 O leads to a capacity of 100 mAh g −1 at − 0.78 V vs Ag/AgCl (based on the weight of the active material) when operated in aqueous 1 M sodium acetate electrolyte. However, low cycling stability was observed, since a drastic loss in specific capacity occurs after the first charge. This study focuses at elucidating the mechanism behind this phenomenon via in situ UV/vis experiments. Subsequently, the dissolution of charged AQS anions into the electrolyte during the first charge of the anode has been identified and quantified. Such understanding of fading mechanism might lead to the design of improved LDH-based electrodes, which utilize redox active anions working in the positive potential range with enhanced cycling ability.
Published: 2023

42. Hybrid security approach for behavioural privacy of business processes in a Cloud environment

Author: Abdmeziem, Farah, Boukhedouma, Saida, Oussalah, Mourad Chabane, USTHB DZA, Partenaires IRSTEA, Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), and LNCS
Subjects: [INFO]Computer Science [cs]
Abstract: International audience; Nowadays, many public and private institutions are inter-ested to benefit from the advantages of the Cloud Computing technol-ogy, especially when it comes to massive data storage. However, thereis one issue related to security that impedes the widely adoption of thistechnology. Indeed, using cloud services for data storage implies that theclients must trust the Cloud provider with their data and even morecritically losing full control on data. Nevertheless, there exists a solutionto bypass this security issue that consists in securing data on the client’spremises, i.e. before it is sent to the Cloud provider for storage. One ofthe widely used security mechanism to this matter is data encryption.Encryption comes in two main schemes symmetric and asymmetric witha number of encryption algorithms for each scheme. Hence, relying onthe data encryption mechanism the contribution of this work is three-fold. First of all, we propose a meta-model that represents the result ofthe study and the comparison of the state-of-the-art works. Thus, themeta-model can be used as a referential to instantiate different solutionsto data security. Second, we use our meta-model to propose a novel ap-proach for securing data in a Cloud environment. The solution relies onsecurity patterns that provide a customized data encryption. Finally, en-cryption has surely proven its security effectiveness but comes with somedrawbacks. Indeed, encryption can be costly in time and induces perfor-mances’ overheads especially when it comes to encrypt massive amountsof data. Plus, these overheads are not without consequences on the envi-ronment and can increase the carbon footprint of servers. Therefore, weextend our meta-model to consider the impact of the encryption securitymechanism on the environment. This extension is used to evaluate ourproposed solution and to show its positive impact on the environment.
Published: 2023

43. Hyperparameter selection for Discrete Mumford–Shah

Author: Lucas, Charles-Gérard, Pascal, Barbara, Pustelnik, Nelly, Abry, Patrice, Laboratoire de Physique de l'ENS Lyon (Phys-ENS), École normale supérieure de Lyon (ENS de Lyon)-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, and Nantes Université (Nantes Univ)
Subjects: non-convex minimization, contour detection, Image and Video Processing (eess.IV), Electrical Engineering and Systems Science - Image and Video Processing, Optimization and Control (math.OC), Stein Unbiased Risk Estimate, [INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV], Signal Processing, FOS: Electrical engineering, electronic engineering, information engineering, FOS: Mathematics, Mumford-Shah functional, [MATH.MATH-OC]Mathematics [math]/Optimization and Control [math.OC], Electrical and Electronic Engineering, Mathematics - Optimization and Control
Abstract: International audience; This work focuses on a parameter-free joint piecewise smooth image denoising and contour detection. Formulated as the minimization of a discrete Mumford-Shah functional and estimated via a theoretically grounded alternating minimization scheme, the bottleneck of such a variational approach lies in the need to fine-tune their hyperparameters, while not having access to ground truth data.To that aim, a Stein-like strategy providing optimal hyperparameters is designed, based on the minimization of an unbiased estimate of the quadratic risk.Efficient and automated minimization of the estimate of the risk crucially relies on an unbiased estimate of the gradient of the risk with respect to hyperparameters. Its practical implementation is performed using a forward differentiation of the alternating scheme minimizing the Mumford-Shah functional, requiring exact differentiation of the proximity operators involved. Intensive numerical experiments are performed on synthetic images with different geometry and noise levels, assessing the accuracy and the robustness of the proposed procedure.The resulting parameter-free piecewise-smooth estimation and contour detection procedure, not requiring prior image processing expertise nor annotated data, can then be applied to real-world images.
Published: 2022

44. Operationalizing circular economy. Reflections on a by-product upcycling value chain construction in the brewing sector

Author: Petiti, Gaelle, Rousselière, Samira, Duchaine, Sibylle, Korbel, Emilie, Cariou, Véronique, Mikhaylin, Sergey, Audebrand, Luc, K., Centre de Recherches sur l'Action Politique en Europe (ARENES), Université de Rennes (UR)-Institut d'Études Politiques [IEP] - Rennes-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Centre National de la Recherche Scientifique (CNRS), Biomarqueurs prédictifs de la progression des metaplasies et dysplasies des epitheliums (Biométadys), Université de Nantes (UN), Laboratoire d'économie et de management de Nantes Atlantique (LEMNA), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes Université - Institut d'Administration des Entreprises - Nantes (Nantes Univ - IAE Nantes), Nantes Université - pôle Sociétés, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sociétés, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-FR 3473 Institut universitaire Mer et Littoral (IUML), Le Mans Université (UM)-Université d'Angers (UA)-Université de Bretagne Sud (UBS)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Le Mans Université (UM)-Université d'Angers (UA)-Université de Bretagne Sud (UBS)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Laboratoire de génie des procédés - environnement - agroalimentaire (GEPEA), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - Institut Universitaire de Technologie Saint-Nazaire (Nantes Univ - IUT Saint-Nazaire), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Statistique, Sensométrie et Chimiométrie (StatSC), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut des Nutraceutiques et des Aliments Fonctionnels (INAF), Université Laval [Québec] (ULaval), and RFI Food for Tomorrow of France, Pays-de-la-Loire
Subjects: brewer's spent grain, sustainable development, circular economy, by-product, upcycling, General Medicine, [SHS.ECO]Humanities and Social Sciences/Economics and Finance
Abstract: International audience; The concept of a circular economy has arisen in response to the problems related to the limits of the dominant linear economic system in contemporary societies and of the finite resources of our planet. The transition from waste status to a raw material by reusing it makes it possible to modify its value for future users and thus to redistribute this value. This article focuses on the case of spent grain to illustrate the role of the circular economy in food transition. Bases on a series of interviews, the paper discusses business modeling to operationalize sustainable development in the food sector and presents a discussion and conclusion on the advantages and limitations of the deployment of the circular economy in the brewing industry, taking into account and understanding the interests and constraints of various stakeholders.
Published: 2022

45. Torus stability under Kato bounds on the Ricci curvature

Author: Carron, Gilles, Mondello, Ilaria, Tewodrose, David, Laboratoire de Mathématiques Jean Leray (LMJL), Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Laboratoire Analyse et Mathématiques Appliquées (LAMA), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)-Université Gustave Eiffel, and Carron, Gilles
Subjects: Mathematics - Differential Geometry, Differential Geometry (math.DG), [MATH.MATH-DG]Mathematics [math]/Differential Geometry [math.DG], General Mathematics, FOS: Mathematics, Mathematics::Metric Geometry, Mathematics::Differential Geometry, [MATH.MATH-DG] Mathematics [math]/Differential Geometry [math.DG], Mathematics::Geometric Topology, Mathematics::Symplectic Geometry
Abstract: We show two stability results for a closed Riemannian manifold whose Ricci curvature is small in the Kato sense and whose first Betti number is equal to the dimension. The first one is a geometric stability result stating that such a manifold is Gromov-Hausdorff close to a flat torus. The second one states that, under a stronger assumption, such a manifold is diffeomorphic to a torus: this extends a result by Colding and Cheeger-Colding obtained in the context of a lower bound on the Ricci curvature., 24 pages. Comments are welcome!
Published: 2022

46. Editorial Board contributions celebrating the 60th Anniversary of IJPR: Part 3

Author: Dolgui, Alexandre, Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), and Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)
Subjects: [INFO.INFO-AU]Computer Science [cs]/Automatic Control Engineering, Strategy and Management, [INFO]Computer Science [cs], [INFO.INFO-RO]Computer Science [cs]/Operations Research [cs.RO], Management Science and Operations Research, Industrial and Manufacturing Engineering
Abstract: International audience
Published: 2022

47. Robust optimization approaches for purchase planning with supplier selection under lead time uncertainty

Author: Simon Thevenin, Oussama Ben-Ammar, Nadjib Brahimi, Département Automatique, Productique et Informatique (IMT Atlantique - DAPI), IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT), Modélisation, Optimisation et DEcision pour la Logistique, l'Industrie et les Services (LS2N - équipe MODELIS), Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Nantes Université (Nantes Univ), EuroMov - Digital Health in Motion (Euromov DHM), IMT - MINES ALES (IMT - MINES ALES), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-Université de Montpellier (UM), ESC Rennes School of Business, and ESC Rennes School of Business (ESC [Rennes])
Subjects: Information Systems and Management, General Computer Science, Modeling and Simulation, Lot-sizing, Production, [INFO.INFO-RO]Computer Science [cs]/Operations Research [cs.RO], Management Science and Operations Research, Robust optimization, Supplier selection, Purchasing, Lead time Uncertainty, Industrial and Manufacturing Engineering
Abstract: International audience; Supplier reliability is a critical issue for manufacturing companies. Delivery delays from suppliers create backlog and firefighting on the shop floors. To avoid disruption and hedge against supplier lead time uncertainty, companies rely on diversification, multi-sourcing, and safety lead times. In multi-sourcing, the buyer might order the same product (raw material) from different suppliers. The design of a robust and cost-efficient purchasing/ordering plan in multi-sourcing is a complex task which has a strong impact on the performance of the company. In this study, we investigate the use of robust optimization for the integrated lot-sizing and supplier selection problem under lead time uncertainty. More specifically, we use polyhedral budgeted uncertainty sets. The resulting model determines the ideal lot sizes to minimize the total costs taking into consideration suppliers’ reliability and prices. To solve this problem, a row and column generation approach is proposed. To alleviate scalability issues, we enhance the row and column generation through a robust counterpart formulation, and we propose an efficient fix-and-optimize approach. Our extensive computational experiments show that the fix-and-optimize approach yields good quality solutions within a reasonable amount of computational time. We provide insights into supplier diversification based on the risk profile of the decision-maker. One of the conclusions is that an extremely risk-averse decision-maker selects a single supplier, namely the most reliable one even if it does not offer the lowest price.
Published: 2022

48. Ensemble-Based Deep Learning Model for Network Traffic Classification

Author: Ons Aouedi, Kandaraj Piamrat, Benoit Parrein, Laboratoire des Sciences du Numérique de Nantes (LS2N), Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), Institut Mines-Télécom [Paris] (IMT)-Institut Mines-Télécom [Paris] (IMT)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ), Software Stack for Massively Geo-Distributed Infrastructures (STACK), Inria Rennes – Bretagne Atlantique, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria)-Laboratoire des Sciences du Numérique de Nantes (LS2N), Nantes Université (Nantes Univ)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique), STR (LS2N - équipe STR ), and Nantes Université (Nantes Univ)-Institut National de Recherche en Informatique et en Automatique (Inria)-Centre National de la Recherche Scientifique (CNRS)-IMT Atlantique (IMT Atlantique)
Subjects: machine learning, Computer Networks and Communications, decision tree, ensemble learning, deep learning, [INFO]Computer Science [cs], Electrical and Electronic Engineering, Blending, traffic classification
Abstract: International audience; Network Traffic Classification enables a number of practical applications ranging from network monitoring to resource management, with security implications as well. Nowadays, traffic classification has become a challenging task in order to distinguish among a variety of applications due to the huge amount of generated traffic. Therefore, developing Machine Learning (ML) models, which can successfully identify network applications, is one of the most important tasks. However, among the ML models applied to network traffic classification so far, no model outperforms all the others. To solve these issues, this paper proposes a novel Deep Learning (DL)-based approach that incorporates multiple Decision Tree based models. This approach employs a non-linear blending ensemble method by combining tree-based classifiers through DL in order to maximize generalization accuracy. This ensemble consists of two levels called base classifiers and meta-classifiers. In the first level, Decision Tree-based models are used as the base classifiers while in the second level, DL is used as a meta-model to combine the outputs of the base classifiers. Using two publicly available datasets, we show that our proposed ensemble is suitable for network traffic classification and outperforms the linear blending (using logistic regression as meta-model) as well as several well-known ML models, which are Support Vector Machine (SVM), Decision Tree (DT), Random Forest (RF), Multi-Layer Perceptron (MLP), AdaBoost, K-Nearest Neighbors (KNN), LightGBM, Catboost, and XGBoost.
Published: 2022

49. Trajectorial hypocoercivity and application to control theory

Author: Dietert, Helge, Hérau, Frédéric, Hutridurga, Harsha, Mouhot, Clément, Université Paris Cité (UPCité), Sorbonne Université (SU), Institut de Mathématiques de Jussieu - Paris Rive Gauche (IMJ-PRG (UMR_7586)), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Mathématiques Jean Leray (LMJL), Centre National de la Recherche Scientifique (CNRS)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Indian Institute of Technology Bombay (IIT Bombay), University of Cambridge [UK] (CAM), ANR-18-CE40-0027,SingFlows,Ecoulements avec singularités : couches limites, filaments de vortex, interaction vague-structure(2018), and European Project: 279600,EC:FP7:ERC,ERC-2011-StG_20101014,MATKIT(2011)
Subjects: Hypocoercivity, Mathematics - Analysis of PDEs, divergence inequality, spectral gap, kinetic theory, FOS: Mathematics, [MATH.MATH-AP]Mathematics [math]/Analysis of PDEs [math.AP], General Medicine, Fokker-Planck, controllability, Bogovosiǐ operator, Analysis of PDEs (math.AP)
Abstract: We present the quantitative method of the recent work arXiv:2209.09340 in a simple setting, together with a compactness argument that was not included in arXiv:2209.09340 and has interest per se. We are concerned with the exponential stabilization (spectral gap) for linear kinetic equations with degenerate thermalization, i.e. when the collision operator vanishes on parts of the spatial domain. The method in arXiv:2209.09340 covers both scattering and Fokker-Planck type operators, and deals with external potential and boundary conditions, but in these notes we present only its core argument and restrict ourselves to the kinetic Fokker-Planck in the periodic torus with unit velocities and a thermalization degeneracy. This equation is not covered by the previous results of Bernard and Salvarani (2013), Han-Kwan and L\'eautaud (2015), Evans and Moyano (arXiv:1907.12836)., Comment: 10 pages, 1 figure
Published: 2022

50. Mechanical stress driven by rigidity sensing governs epithelial stability

Author: Surabhi Sonam, Lakshmi Balasubramaniam, Shao-Zhen Lin, Ying Ming Yow Ivan, Irina Pi-Jaumà, Cecile Jebane, Marc Karnat, Yusuke Toyama, Philippe Marcq, Jacques Prost, René-Marc Mège, Jean-François Rupprecht, Benoît Ladoux, Institut Jacques Monod (IJM (UMR_7592)), Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physique Théorique - UMR 7332 (CPT), Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), CPT - E5 Physique statistique et systèmes complexes, Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Université de Toulon (UTLN)-Centre National de la Recherche Scientifique (CNRS), Mechanobiology Institute [Singapore] (MBI), National University of Singapore (NUS), Sorbonne Université - Faculté de Physique (UFR 925), Sorbonne Université (SU), Procédés et Mécanique des Matériaux (PMM), Institut de Recherche en Génie Civil et Mécanique (GeM), Centre National de la Recherche Scientifique (CNRS)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes université - UFR des Sciences et des Techniques (Nantes univ - UFR ST), Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Sciences et technologie, Nantes Université (Nantes Univ)-Nantes Université - Institut Universitaire de Technologie Saint-Nazaire (Nantes Univ - IUT Saint-Nazaire), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - Ecole Polytechnique de l'Université de Nantes (Nantes Univ - EPUN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Nantes (Nantes Univ - ECN), Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), ANR-16-CONV-0001,CENTURI,CenTuri : Centre Turing des Systèmes vivants(2016), ANR-17-CE13-0012,MecanoAdipo,Mécanotransduction des cellules souches adipeuses et applications pour l'ingénierie tissulaire(2017), ANR-20-CE30-0023,COVFEFE,Hydrodynamique Covariante, Fluctuante et Active des Ecoulements Epithéliaux(2020), ANR-19-CE13-0016,MyoFuse,Contrôle génétique et mécanique de la fusion des myoblastes(2019), Biophysique (BIOPHYSIQUE), Institut Lumière Matière [Villeurbanne] (ILM), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire Physico-Chimie Curie [Institut Curie] (PCC), and Institut Curie [Paris]-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)
Subjects: [PHYS]Physics [physics], [SDV]Life Sciences [q-bio], General Physics and Astronomy, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
Abstract: Epithelia act as a barrier against environmental stress and abrasion and in vivo they are continuously exposed to environments of various mechanical properties. The impact of this environment on epithelial integrity remains elusive. By culturing epithelial cells on 2D hydrogels, we observe a loss of epithelial monolayer integrity through spontaneous hole formation when grown on soft substrates. Substrate stiffness triggers an unanticipated mechanical switch of epithelial monolayers from tensile on soft to compressive on stiff substrates. Through active nematic modelling, we find unique patterns of cell shape texture called nematic topological defects that underpin large isotropic stress fluctuations at certain locations thereby triggering mechanical failure of the monolayer and hole opening. Our results show that substrate stiffness provides feedback on monolayer mechanical state and that topological defects can trigger stochastic mechanical failure, with potential application towards a mechanistic understanding of compromised epithelial integrity in bacterial infection, tumor progression and morphogenesis.
Published: 2022

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