1. Type 1 Invariant Natural Killer T Cells Drive Lung Fibrosis.
- Author
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Calamita, Emily, Liu, Wing Han, Ogger, Patricia P., Griffin, Leia, Michalaki, Christina, Murphy, Faye, Worrell, Julie, McCarthy, Cormac, Agro, Albert, Hertz, Marc, Maher, Toby M., Lloyd, Clare M., Molyneaux, Philip, Kumar, Vipin, and Byrne, Adam J.
- Subjects
KILLER cells ,CYTOTOXIC T cells ,PULMONARY fibrosis ,IDIOPATHIC pulmonary fibrosis ,RETINOIC acid receptors ,T cell receptors - Abstract
The article presents a study which investigated the role of pulmonary natural killer T cells (NKT) populations in IPF by analyzing bronchoalveolar lavage (BAL) fluid from patients with idiopathic pulmonary fibrosis (IPF) and healthy control subjects by quantitative polymerase chain reaction (PCR) and flow cytometry. Topics discussed include clinical characteristics of IPF, how the role of NKT cells was ascertained, and how the severity of lung lesions was graded.
- Published
- 2024
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