Type 1 Invariant Natural Killer T Cells Drive Lung Fibrosis.

Authors :: Calamita, Emily
Liu, Wing Han
Ogger, Patricia P.
Griffin, Leia
Michalaki, Christina
Murphy, Faye
Worrell, Julie
McCarthy, Cormac
Agro, Albert
Hertz, Marc
Maher, Toby M.
Lloyd, Clare M.
Molyneaux, Philip
Kumar, Vipin
Byrne, Adam J.
Source :: American Journal of Respiratory & Critical Care Medicine; 8/15/2024, Vol. 210 Issue 4, p521-523, 3p
Publication Year :: 2024
Abstract: The article presents a study which investigated the role of pulmonary natural killer T cells (NKT) populations in IPF by analyzing bronchoalveolar lavage (BAL) fluid from patients with idiopathic pulmonary fibrosis (IPF) and healthy control subjects by quantitative polymerase chain reaction (PCR) and flow cytometry. Topics discussed include clinical characteristics of IPF, how the role of NKT cells was ascertained, and how the severity of lung lesions was graded.