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2 results on '"Muge Koyun"'

1. 3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering

Author

Elif Saatcioglu, Muge Koyun, Songul Ulag, Ali Sahin, Betul Karademir Yilmaz, Burak Aksu, and Oguzhan Gunduz

Subjects
Chitosan, Maclura pomifera, Osage orange, Wound healing, 3D printing, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627
Abstract

In this study, three-dimensional tissue scaffolds were fabricated using a 3D printing process. Chitosan (CS) was used as a matrix polymer, and Osage orange extract (OGE) with different amounts was added as a bioactive material. The scaffolds were characterized by SEM, FTIR, tensile testing, antibacterial, and biocompatibility tests. The SEM images revealed that scaffolds had homogeneous morphology, and the size of the pores ranged from 160 µm to 270 µm. FTIR spectrum of the extracted Osage Orange confirmed the successful extraction of the Osage Orange. The OGE addition decreased the swelling capacity of the CS scaffold proportionally. Biocompatibility results proved the biostability properties of the scaffolds. According to the results, the antibacterial activity of the scaffolds against the Staphylococcus Aureus (S. aureus) and Enterococcus Faecalis (E. faecalis) should be provided after detailed optimization.

Published
2021
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2. 3D printing of Osage orange extract/Chitosan scaffolds for soft tissue engineering

Author

Oguzhan Gunduz, Songul Ulag, Elif Saatcioglu, Betul Karademir Yilmaz, Ali Sahin, Burak Aksu, and Muge Koyun

Subjects
chemistry.chemical_classification, Chitosan, RC620-627, biology, Biocompatibility, Nutrition. Foods and food supply, Osage orange, Extraction (chemistry), Swelling capacity, Wound healing, Orange (colour), Polymer, 3D printing, biology.organism_classification, Enterococcus faecalis, chemistry.chemical_compound, chemistry, Maclura pomifera, TX341-641, Antibacterial activity, Nutritional diseases. Deficiency diseases, Nuclear chemistry
Abstract

In this study, three-dimensional tissue scaffolds were fabricated using a 3D printing process. Chitosan (CS) was used as a matrix polymer, and Osage orange extract (OGE) with different amounts was added as a bioactive material. The scaffolds were characterized by SEM, FTIR, tensile testing, antibacterial, and biocompatibility tests. The SEM images revealed that scaffolds had homogeneous morphology, and the size of the pores ranged from 160 µm to 270 µm. FTIR spectrum of the extracted Osage Orange confirmed the successful extraction of the Osage Orange. The OGE addition decreased the swelling capacity of the CS scaffold proportionally. Biocompatibility results proved the biostability properties of the scaffolds. According to the results, the antibacterial activity of the scaffolds against the Staphylococcus Aureus (S. aureus) and Enterococcus Faecalis (E. faecalis) should be provided after detailed optimization.

Published
2021

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