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2. A mycolic acid--specific CD1-restricted T cell population contributes to acute and memory immune responses in human tuberculosis infection

Author

Montamat-Sicotte, Damien J., Millington, Kerry A., Willcox, Carrie R., Hingley-Wilson, Suzie, Hackforth, Sarah, Innes, John, Kon, Onn Min, Lammas, David A., Minnikin, David E., Besra, Gurdyal S., Willcox, Benjamin E., and Lalvani, Ajit

Subjects
Health aspects, Tuberculosis vaccines -- Health aspects, Lipids -- Health aspects, Tuberculosis -- Health aspects, Immune response -- Health aspects, T cells -- Health aspects
Abstract

Current tuberculosis (TB) vaccine strategies are largely aimed at activating conventional T cell responses to mycobacterial protein antigens. However, the lipid-rich cell wall of Mycobacterium tuberculosis (M. tuberculosis) is essential [...]

Published
2011
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