1. Diagnosis and Management of Autoimmune Myasthenia Gravis
- Author
-
Corrado Angelini
- Subjects
medicine.medical_specialty ,Immune-globulin ,medicine.medical_treatment ,Models, Neurological ,Monoclonal-antibodies ,Ciclosporin ,Research-and-development ,Disease ,Acetylcholinesterase-inhibitors, therapeutic use ,Ambenonium-chloride, therapeutic use ,Azathioprine, therapeutic use ,Ciclosporin, therapeutic use ,Corticosteroids, therapeutic use ,Immune-globulin, therapeutic use ,Monarsen, therapeutic use ,Monoclonal-antibodies, therapeutic use ,Myasthenia-gravis, treatment ,Neostigmine, therapeutic use ,Plasma-exchange ,Pyridostigmine, therapeutic use ,Rituximab, therapeutic use ,Pharmacotherapy ,Immune system ,Myasthenia Gravis ,Azathioprine ,medicine ,Humans ,Corticosteroids ,Pharmacology (medical) ,Ambenonium-chloride ,Intensive care medicine ,Severe disability ,Adverse effect ,Myasthenia-gravis ,Pyridostigmine ,treatment ,business.industry ,Acetylcholinesterase-inhibitors ,Monarsen ,General Medicine ,Thymectomy ,medicine.disease ,Neostigmine ,Myasthenia gravis ,therapeutic use ,Immunology ,Etiology ,Cholinesterase Inhibitors ,Rituximab ,business ,Immunosuppressive Agents - Abstract
Earlier diagnosis and the availability of effective treatments have reduced the burden of high mortality and severe disability previously associated with myasthenia gravis (MG). Consequently, the prognosis of MG is now much improved. However, despite extensive knowledge of MG and its aetiology, diagnosing the disease remains problematic and can be delayed because of its nonspecific and fluctuating symptoms, and the management of MG is associated with considerable limitations. Current treatments based on immunomodulation are associated with adverse effects arising from prolonged immune suppression. There is a need for improved awareness among primary caregivers about this relatively rare, but treatable, disease.
- Published
- 2011
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