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Diagnosis and Management of Autoimmune Myasthenia Gravis
- Source :
- Clinical Drug Investigation. 31:1-14
- Publication Year :
- 2011
- Publisher :
- Springer Science and Business Media LLC, 2011.
-
Abstract
- Earlier diagnosis and the availability of effective treatments have reduced the burden of high mortality and severe disability previously associated with myasthenia gravis (MG). Consequently, the prognosis of MG is now much improved. However, despite extensive knowledge of MG and its aetiology, diagnosing the disease remains problematic and can be delayed because of its nonspecific and fluctuating symptoms, and the management of MG is associated with considerable limitations. Current treatments based on immunomodulation are associated with adverse effects arising from prolonged immune suppression. There is a need for improved awareness among primary caregivers about this relatively rare, but treatable, disease.
- Subjects :
- medicine.medical_specialty
Immune-globulin
medicine.medical_treatment
Models, Neurological
Monoclonal-antibodies
Ciclosporin
Research-and-development
Disease
Acetylcholinesterase-inhibitors, therapeutic use
Ambenonium-chloride, therapeutic use
Azathioprine, therapeutic use
Ciclosporin, therapeutic use
Corticosteroids, therapeutic use
Immune-globulin, therapeutic use
Monarsen, therapeutic use
Monoclonal-antibodies, therapeutic use
Myasthenia-gravis, treatment
Neostigmine, therapeutic use
Plasma-exchange
Pyridostigmine, therapeutic use
Rituximab, therapeutic use
Pharmacotherapy
Immune system
Myasthenia Gravis
Azathioprine
medicine
Humans
Corticosteroids
Pharmacology (medical)
Ambenonium-chloride
Intensive care medicine
Severe disability
Adverse effect
Myasthenia-gravis
Pyridostigmine
treatment
business.industry
Acetylcholinesterase-inhibitors
Monarsen
General Medicine
Thymectomy
medicine.disease
Neostigmine
Myasthenia gravis
therapeutic use
Immunology
Etiology
Cholinesterase Inhibitors
Rituximab
business
Immunosuppressive Agents
Subjects
Details
- ISSN :
- 11732563
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Clinical Drug Investigation
- Accession number :
- edsair.doi.dedup.....a5a2ccd9fc241a5a0dfe85e750b009ce
- Full Text :
- https://doi.org/10.2165/11584740-000000000-00000