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Background: We aimed to elucidate the mechanism of change in mitochondrial fusion- and fission-related mediators for maintaining cell function through the effects of acupuncture treatment and apply findings to a liver disease model. We focused on the optic atrophy-1 (OPA1) and fission protein 1 (Fis1) genes of rat liver cells. Methods: Sprague Dawley rats were divided into a control group (no treatment) and LR2, LR3, LR4 and LR8 groups (acupuncture treatment to those points). Acupuncture was performed on each point for 10 minutes once daily for 4 days. Changes in the mRNA expression of Peroxisome proliferator-activated receptor-gamma coactivator 1-α (PGC-1α) and Fis1 were observed via quantitative real-time polymerase chain reaction (qRT-PCR); changes in OPA1, mitofusin-2 (MFN2), mitofusin-1 (MFN1), dynamin-related protein 1 (DRP1) and adenosine monophosphate-activated protein kinase (AMPK) proteins were observed through western blotting and endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) expressions were observed through immunohistochemistry. Result: OPA1 decreased in the LR3 and LR8 groups and Fis1 increased in the LR2 and LR4 groups. AMPK and PGC-1α decreased significantly in all acupuncture groups. eNOS and nNOS expression reduced in all acupuncture groups. Therefore, acupuncture can regulate mitochondrial fusion/fission by influencing the following mediators: AMPK, PGC-1α, OPA1, Fis1, eNOS and nNOS.

Due to the development of the science and technology, modern society has entered the aging society. Accordingly, the number of the elderly and chronic diseases is rapidly increasing. However, it is difficult for the elderly and chronic patients to respond to changes in ambient temperature due to deterioration of body function and autonomic nervous system function. As the results, it causes the diseases such as hypothermia heat stroke and sunstroke occur, and in the worst case, this causes death. Therefore, this study designed a heating and cooling system that can be applied to the elderly and chronic patients who have difficulty maintaining body temperature in daily life, and can also maintain body temperature in an emergency situation. It was designed and developed to circulate heating and cooling circulating water according to the changes in ascending and descending conditions by measuring the reference body temperature. The minimum cooling temperature of the developed body temperature maintenance device was 8.7 °C, and the maximum heating temperature was 70 °C or higher. In the maintenance experiment of maintaining the temperature used for the agarose gel electrophoresis, it took 4 min to maintain the derby temperature at 37.2 °C to 36.5 °C, and it took 2 min and 40 s to reach 36.5 °C at 35 °C.

The photovoltaic power generation system for input blocking was manufactured to be used for blocking control by separately manufacturing two circuits of DC 180[V] PV strings for smooth experimentation. By attaching the circuit proposed in this study to the separately fabricated circuit input part, interruption and input were repeated, and the presence or absence of an arc and the magnitude of the voltage applied to the cut-off circuit were analyzed. It was possible to suppress constant heat generation by using a relay with a low switching voltage at all times, and offset the high voltage with a low voltage of 2[V] with a parallel type IGBT only when blocking was necessary. By attaching a parallel type IGBT, arc generation could be eliminated, and a safe and efficient cut-off circuit could be constructed.

This study aimed to verify the efficacy of a combined treatment of Jakyakgamcho-tang (JGT) and acupuncture (CV12, ST25, CV4) on colitis induced by dextrane sulfate sodium (DSS). Changes in immuno-mediated factors and metabolites were investigated. Colitis symptoms such as body weight loss and elevated disease activity index were alleviated by the combined treatment. Moreover, treatment with JGT and acupuncture restored the disturbed architecture of colon by suppressing inflammatory cytokine levels of IFN-[Formula: see text] ([Formula: see text] < 0.05), IL-5 ([Formula: see text] < 0.05), and IL-13 ([Formula: see text] < 0.0001) compared with the DSS group. Analysis of metabolic profiles of serum revealed that treatment groups were clearly separated from the DSS group, suggesting that JGT and acupuncture treatment altered serum metabolites. Furthermore, treatments caused opposite metabolite patterns for dimethylbenzimidazole, 1,5-anhydro-D-glucitol, proline, phosphate, glycolic acid, aspartic acid, tryptophan, phthalic acid, ornithine, and glutamic acid compared with the DSS group. The combined treatment group induced more effective metabolite patterns than the JGT group, implying that acupuncture treatment can restore metabolic changes caused by DSS induction. These results indicate that the simultaneous treatment of JGT administration and acupuncture procedure provides better management of the immune function and inflammatory expression of colitis than a single treatment. It is assumed that intestinal microbial control can be achieved by acupuncture stimulation as well as by taking herbal medicine.

LED 광은 진피층에 흡수되어 파장별로 다양한 치료효과로 피부 트러블 등을 개선할 수 있다. 본 논문에서는 여드름을 유발하는 박테리아를 억제하는 효과가 있다고 알려진 420 nm 및 635 nm를 복합 조사할 수 있는 LED 마스크를 개발하여 치료패턴을 설계하고 광출력 특성을 분석하였다. 그 결과 LED 마스크를 이용하여 여드름 치료에 적용할 수 있는 LED 광치료 패턴을 구현하였고, 치료에 사용할 수 있도록 LED 광출력을 7.22 mW까지 구현하였다.

Hepatic diseases, such as hepatonecrosis, hepatitis, and hepatocirrhosis, are associated with mitochondrial dysfunction and increased reactive oxygen species generation and inflammation, ultimately leading to liver failure. In this study, we examined if acupuncture at LR3 can affect mitochondria-related gene expression in a liver damage model of experimentally induced acute liver failure (ALF). ALF was induced by the intraperitoneal injection of D-galactosamine (D-GalN) in experimental rats, who then received either sham (ALF), manual acupuncture (MA), electroacupuncture (EA), or silymarin (PC, positive control) treatment. Liver tissues were extracted from experimental and untreated control rats for histopathological analysis and expression profiling of genes involved in mitochondrial function. Of the 168 mitochondria-related genes profiled, two genes belonging to the solute-carrier transporter family (Slc25a15 and Slc25a25) and Ndufb7 were upregulated. Gamma-glutamylcysteine synthetase was more downregulated in MA than ALF. Furthermore, MA reversed D-GalN-induced inflammatory cell infiltration, destruction of hepatic cell plates, and increase in the levels of the proinflammatory cytokine TNF-α. MA at LR3 can reduce the risk of D-GalN-induced ALF by inducing the expression of metabolic and inflammation-related genes and regulating proinflammatory factor production in hepatic mitochondria.

Recently, as new and renewable energy has been actively supplied, numerous photovoltaic (PV) power generation facilities aimed at constructing zero-energy houses and reducing energy have rapidly developed. In this study, a monitoring device capable of continuously measuring the voltage and temperature data generated by individual PV modules was developed to determine whether a given module is abnormal. To examine the operating characteristics of the developed PV module monitoring device, a 3-kW PV power generation facility was built to conduct a comparative analysis of the changes in the voltage, current, and temperature between the normal group and the abnormal group. As a result, it was possible to determine whether each module was abnormal based on changes in the voltage and temperature measured using the developed monitoring device. Since a simply structured module monitoring device was used to determine whether a PV module was abnormal without using digital algorithms, it was expected that this monitoring device would be applicable to small-scale PV power generation facilities.

In this study, we designed mobile X-ray equipment that generates high-power X-rays, using an internal power source by means of a super-capacitor, and evaluated its safety. The proposed X-ray equipment uses the charging voltage of a battery to store high density energy, supplementing the electric charge of the super-capacitor, which can instantly release a large amount of energy. Further, pulse frequency modulation was applied to produce high voltage and thereby improve energy efficiency. The developed mobile X-ray equipment enables to generate an output of 30 kW and, therefore, can be applied to many diagnostic fields. In addition, various devices and control circuits were employed to ensure convenience and safety of using the equipment in clinical applications. This study analyzed the error ranges regarding tube voltage, tube current, irradiation time, coefficient variation, half-value layer, and the output characteristics. The results showed that the proposed X-ray equipment was able to generate 800mR X-ray power under the condition of 30 kW. The coefficient variation was less than 0.05 at all measurement points, which indicates that it is possible to generate the equal amount of X-ray when the driving conditions are same. Results also showed 51.25% of transmittance at 3.5mmAL in the case of the wire, which is thicker than a common reference of 2.3mmAL and indicates that this new mobile equipment is possible to generate X-rays with relatively high permeability. In conclusion, the findings in this study suggest that the new equipment can generate consistent high-power X-rays and, therefore, can be used safely by minimizing unnecessary re-taking of images and radiation exposure.

Insects are nutritious owing to their high protein content, and are excellent in creating diverse amino acids and fatty acids. As insects are edible and can be used as feed and medicine, they have been industrialized in diverse fields. To enable the efficient growth of insects, thereby making progress in the insect industry, an air-cooled insect-rearing equipment that can control the growth environments such as temperature, humidity and photoperiod, as well as conduct remote monitoring and control was designed and manufactured. In this research, to control the temperature and humidity, two thermoelectric elements and humidifying modules were used. The thermoelectric elements and humidifying modules were set up such that the drive power can be variably-controlled based on the pulsed width modulation signal by the microcontroller (MCU). The manufactured insect-rearing system was used to confirm the temperature and humidity characteristics. The results show that the internal temperature and humidity vary depending on the growth conditions set through the insect-rearing equipment, and that it is possible to stably maintain the internal temperature and humidity.

Mobile X-ray device is widely employed because it is useful for diagnosis in patients having mobility difficulties and in medical emergencies. As various devices for X-ray generation have continued to be developed, X-ray devices can now be used more safely and effectively. However, mobile X-ray devices generate relatively low X-ray doses due to the limitation of the power input. Therefore, the use of mobile X-ray devices is limited to thin parts of body. In this study, a new device was designed in order to increase the usefulness of mobile X-ray devices by offsetting the weaknesses of the existing mobile X-ray devices, rendering them useable independently. A supercapacitor and battery were used as the internal power source for the X-ray generation in the manufactured device. The pulse width modulation (PWM) method is applied to control the tube voltage and current required for generating the X-ray, and the pulse frequency modulation (PFM) method is applied to the control to generate the high voltage in order to enhance the precision and efficiency. The manufactured X-ray device was used to evaluate the control signal, frequency, and output characteristics according to changes in tube voltage and current. Based on the results of X-ray generation, it is confirmed that precise control was achieved by X-ray generation increases linearly with increasing tube voltage and tube current. This means that precise control of the manufactured mobile X-ray device is passible. In addition, the study confirmed that stable output was achieved by checking the tube voltage, tube current and exposure rate during the exposure times by high power condition.

Low level laser therapy (LLLT) has facilitated an improvement in acupuncture treatment. In this study, we stimulated Shaochong (HT9), Dadun (LR1), Shaohai (HT3), and Yingu (KI10) acupoints with pulsed laser diodes 532 nm [green laser] and 658 nm [red laser] in rats with induced middle cerebral artery occlusion(MCAO). The animals were divided into 6 groups: intact control; MCAO control without LLLT; LLLT with red laser at HT9·LR1 and HT3·KI10 (RR); LLLT with green laser at HT9·LR1 and HT3·KI10 (GG); LLLT with green laser at HT9·LR1 and red laser at HT3·KI10 (GR); and LLLT with red laser at HT9·LR1 and green laser at HT3·KI10 (RG). We evaluated the immunohistochemical changes in the hippocampal CA1 region, and complete blood count changes. Compared to the MCAO control group, the RG group showed a significant decrease in Bax and cytochrome c levels in the hippocampus, and a significant increase in hemoglobin level, hematocrit, total white blood cell, neutrophil, lymphocyte, monocyte, and erythrocyte counts.

In this study, a basic research on artificial liver was performed for its application to people on the waiting list of liver transplant or patients with hepatic insufficiency. Artificial livers are generally classified into mechanic type, bioartificial type, and hybrid type. An extracorporeal circulation device was examined herein, which is indispensable in the application of an artificial liver, for its effectiveness in supporting the recovery of liver functions. Extracorporeal circulation system is a treatment and life-support system which sends out the patient's blood, removes toxicity by various methods, and then sends the blood back to the interior of the body. This study used an extracorporeal circulation system which enables the Plasma Perfusion by CVVH method, and applied the program of Bioateco corp. Animals with acute hepatic insufficiency were produced to apply the extracorporeal circulation device. As a result, their ammonia, bilirubin, SGOT, SGPT, and bile acid levels rose, confirming the liver function restoration in the experimental animals.

In order to assess the impact of proprioceptive exercises on the position sense ability of the knee joint, we conducted an analysis using Biodex System 3pro®, targeting 42 ordinary people (male=22, female=20). After applyingproprioceptive exercise, we measured changes in balance and flexibility, and active articular position sense (AAPS), depending on gender. To find out the change in each measurement item variable, we carried out dependentt-tests. The statistical significance level was set to 0.05. The research showed that after applying the proprioceptiveexercise, AAPS was significantly improved for both men and women (p

The purpose of this research is to utilizing the Tetrax balance measuring instrument in order to analyze the postural balance of males and females in their 30 s diagnosed with chronic lower back pain who have followed a 12-week rehabilitation exercise program. The research also examines the effects on any change in back pain level. In terms of the variables in this research, postural balance (left/right, front/back, postural balance) and pain level change (0~100 mm) were measured. Pre-/post-experimental differences were assessed using the paired-t test. In addition, to identify any gender gap, we set the preliminary scores as a covariate and ran the Analysis of Covariance. Statistical significance (a) herein was set at 0.05. As a result of this research experiment, the left/right, front/back, and overall postural balance were found to increase in both the male and female cases, but with no statistical significance or gender gap. However, both males and females showed a significant decrease in their back pain levels. These findings demonstrate the necessity of continuing clinical research based on the Tetrax equipment for scientific evaluation of the effects of rehabilitation exercises on chronic lower back pain patients and their balancing ability.

Objectives To determine the prevalence of antimicrobial resistance in the normal rectal flora of patients undergoing transrectal ultrasonography-guided prostate biopsy in Korea. Methods Between May 2010 and October 2010, rectal swabs were cultured from patients before transrectal ultrasonography-guided prostate biopsy in three tertiary referral centers of Jeonbuk Province, Korea. Rectal swabs were collected using cotton-tipped culture swabs in a standard collection system immediately before prostate biopsy. The swabs were cultured on eosin methylene blue and McConkey agar at 37°C. Antimicrobial sensitivity tests were carried out according to National Committee for Clinical Laboratory Standards guidelines. Results Of the 160 patients who had a rectal swab taken before prostate biopsy, microorganisms were isolated in 125 patients. Escherichia coli was isolated from the rectal swabs of 95 patients. The mean age was 68.1 years, the median serum prostate specific antigen was 5.6 ng/mL and the mean prostate volume measured by transrectal ultrasonography was 43.8 mL. Of the E. coli, 33.7%, 29.1%, 26.7%, 23.3%, 12.8%, 9.3%, 5.8%, 1.2% and 0% were resistant to ampicillin, piperacillin, levofloxacin, trimethoprim sulfamethoxazole, gentamicin, cephalothin, cefotaxim, amikacin and meropenem, respectively. Conclusions There is a high level of resistance to ciprofloxacin and ampicillin, and a very low level of resistance to amikacin in the E. coli in the bowel flora. The prevalence of resistance to ciprofloxacin in Korea is significantly higher than that reported in Western countries.

This study aims to develop an electronic moxibustion device for the quantification of moxibustion, which progresses a critical role in traditional oriental medicine as well as to assess the characteristics of heating. The assessment revealed that the proposed electronic moxibustion treatment device can reduce the time required for reaching the desired heat level and continue to provide heat consistently. Moreover, heat transmitted to the treated area was found to correspond to a heating pattern of the proposed electronic moxibustion device. It proved both quantitative control and safe treatment for the proposed electronic moxibustion device.

Light amplification by stimulated emission of radiation (LASER) diode irradiation (LDI) has some beneficial effects on the wound healing. However, little is known about the biochemical effect of LDI on wound healing. We have performed animal study to clarify the effect of LDI on wound healing based on microscopic findings.Eight-month-old male rats (NTacSam:SD, SamtakoBioKorea), weighting 250-300 g, were used. Round blade, of 1 cm diameter, was penetrated through the skin and subcutaneous level after elevating the skin just above the thoracic spine of the rats. Laser diode of 655, 785, and 850 nm wavelengths were irradiated to the skin wound for 9 days, 20 min a day. Eight rats were used in each four groups including non-irradiated group. Immunochemical staining was carried out to evaluate pan-cytokeratin and actin, and Masson's trichrome staining was carried to evaluate the cellular and protein components relating to wound healing. Wound size was measured on 9th postoperative day with computer system.Collagen formation was graded as 2+, 3+, and 4 + in the order of non-radiation group, 655, 785, and 850 nm irradiation groups, respectively. Myofibroblast was formed more abundantly in LDI group than in non-irradiated group. The mean values of proliferating cell nuclear antigen (PCNA) were 67.8 ± 5.0, 84.0 ± 4.6, 78.0 ± 6.8, and 74.2 ± 4.0 nm in the order of non-radiation group, 655, 785, and 850 nm irradiation groups, respectively. Mean values of defect size were 2,840 ± 124 um, 1,689 ± 125 um, 1,254 ± 94 um, and 1,423 ± 113 in the order of non-radiation group, 65, 785, and 850 nm groups, respectively.LDI has beneficial effects on the formation of fibroblast and collagen, and results in better wound healing.

There are many methods of healing wounds. Among these, light therapy is reported to be beneficial, as beams assist the human body in treating, sterilizing, and regenerating cells. Both Laser and LED irradiation with specific wavelengths induce proliferation of fibroblasts depending on the wound area or wavelength and are effective in wound healing. This study used 8-week-old 250---300 g Male Sprague---Dawley Rats (ILAR Code: NTacSam:SD). The experiment was carried out for the non-irradiation group and the Red---Green---Blue LEDs irradiation groups (n of each group = 5). The experiment animals were relieved for 24 h after wounds had been excised and then the Red---Green---Blue LEDs irradiation groups were given irradiation therapy over 9 days 1 h per day. Immunohistochemical staining was conducted for cytokeratin in order to precisely measure the defect size. Also, Masson's trichrome staining was conducted for comparison of collagen between the Red---Green---Blue LEDs irradiation groups and the non-irradiation group. Animals treated with Blue LEDs irradiation (p < 0.05), Green LEDs irradiation (p < 0.05), and Red LEDs irradiation (N.S.) healed at a faster rate than non-irradiated group. The LEDs irradiated groups also had more collagen, according to Masson's trichrome staining for collagen analysis. The Red---Green---Blue LEDs irradiation had a beneficial effect on wound healing and could probably replace low power laser treatment.

An isolator transmits light in the forward direction and blocks light from passing in the reverse direction. It is regarded an essential optical component in medical, industrial, and research lasers for blocking reflection beams that cause optical damage and noise. It is also used as a communicative light intensifier to expand the lifespan of devices and enhance transmission quality. This study analyzed the characteristics of the core components in the construction of a polarization-independent isolator, namely, the walk-off polarizer and the Faraday rotator. Measurement of the extinction ratio of the resultant walk-off polarizer revealed that the ratio between the vertical and horizontal rays was 1,050:1 with a laser output of 0.032 W and 1,010:1 with a laser output of 2.68 W, thus presenting ratios similar to 1,000:1. In addition, the walk-off polarizer and Faraday rotator constructed in this study were used to compare output changes according to changes in power of input light and to check the penetration ratio. Results from the study presented variations in output value according to changes in power of input light. However, the average penetration ratio remained relatively consistent (~81.4%).

Nowadays, with improvement of economical income and life qualities, life pattern changes have been brought such as increasing of avocational activities. Consequently, following those life trends, utilization of car is getting increased. Thus, the perceptions of car have been changed from the only means of transport in the past to a 2nd residental space. that is why the car`s endo environmental factors are getting so important. Air conditioner regulating air ventilization in vehicle`s indoor automatically sets the right temperature based on the differences of indoor and outdoor`s temperature with development of advanced functions to provide better environmental qualities in vehicle. However, even those advanced techniques for functional development are got so diverse though, the essential technique for preventing the growth of bateria and mold inside of the air conditioner are not even severals. Especially, evaporator one of the vehicle air conditioning equipments generates cooled air by vaporizing refrigerant in liquid state with the water as the adduct for this reactions. It has structural difficulties for water vaporation then cause the growth of germs. That`s why this reseach was focused on the way of eliminating germs in the vehicle air conditioner efficiently. Direct air sterilizer by using UVC(Ultraviolet C) is manufactured and that performances are evaluated.

Department of Electrical and Electronic Engineering, Graduate School, Dongshin University, Naju 520-714, Korea(Received August 22, 2011; Revised September 9, 2011; Accepted September 14, 2011)Abstract: An optical lens is usually produced in the manner of high temperature compression molding with tungsten carbide alloy molding cores, it is necessary to develop and study technology for super-precision processing of molding cores and coating the core surface. As main methods used in surface improvement technologies using thin film, DLC present high hardness, chemical stability, and outstanding durability of abrasion to be extensively applied in various industrial fields. In this study, the effect of DLC coating of a thin film by means of the FVAS (filtered vacuum arc source) analyzed the characteristics of thin film. Surface roughness before and after DLC coating was measured and the result showed that the surface roughness was improved after coating as compared to before coating. In conclusion, it was observed that DLC coating of the ultra hard alloy core surface for molding had an effect on improving the surface roughness and shape of the core surface. It is considered that this will have an effect on improving abrasion resistance and the service life of the core surface.Keywords: Tungsten carbide, Diamond liked carbon, Thin film, Filtered vacuum arc source

Rhenium-Iridium(Re-Ir) thin films were deposited onto the tungsten carbide(WC) molding core by sputtering system. The Re-Ir films were prepared by multi-target sputtering with iridium, rhenium and chromium as the sources. Argon and nitrogen were inlet into the chamber to be the plasma and reactive gases. The Re-Ir thin films were prepared with targets having atomic percent of 3:7 and the Re-Ir thin films were formed with 240 nm thickness. The Re-Ir thin films on tungsten carbide molding core were analyzed by scanning electron microscope(SEM) and surface roughness. Also, adhesion strength and coefficient friction of Re-Ir thin film were examined. The Re-Ir coating technique has been intensive efforts in the field of coating process because the coating technique and process have been their feature, like hardness, high elasticity, abrasion resistance and mechanical stability and also have been applied widely the industrial and biomedical areas. In this report, tungsten carbide(WC) molding core was manufactures using high performance precision machining and the efforts of Re-Ir coating on the surface roughness.

Light can be divided into ultraviolet rays, visible rays, and infrared rays depending on the wavelengths. Visible rays with specific wavelength are those predominantly used for would treatment. Especially low level laser irradiates into cells, effectively stimulating cellular tissues and activating cellular function. This study was intended to verify the effect of white LED irradiation therapy on wound recovery in animal tests by applying white LED irradiator, which was independently designed and developed to emit beams of similar wavelength to that of a laser. The designed LED Irradiator was used to find out how white LED light source affected the skin wound of SD-Rat(Sprague-Dawley Rat). We divided the participants into two groups; white LED irradiation group which was irradiated 1 hour a day for 9 consecutive days, and none irradiation group. The results showed that the study group had lower incidence of inflammation and faster recovery, compared with the control group.

Medical X-ray has been brought many changes according to the rapid development of high technology. Especially, for high-voltage generator which is the most important in X-ray generation the traditional way is to use high-voltage electric transformers primarily. However, since it is large and heavy and the ripple rate of DC high-voltage applied to X-ray tube is too big, it has a disadvantage of low X-ray production efficiency. To solve these problems, the studies about high-voltage power supply are now proceeding. At present, the high-voltage generator that generates high-voltage by making high frequency using inverter control circuit consisting of semiconductor device is mainly used. High-voltage generator using inverter has advantages in the diagnosis using X-ray including high performance with short-term use, miniaturization of power supply and ripple reduction. In this study, the X-ray high-voltage device with inverter type using pulse width modulation scheme to the control of tube voltage and tube current was designed and produced. For performance evaluation of produced device, the control signal analysis, irradiation dose change and beam quality depending on the load variation of tube voltage and tube current were evaluated.

For mass information transfer, the optical communication using optic fiber has been widely used. Especially, in the field of medical image, the large data is digitalized based on the standard image and it is used for telemedicine with this method. Therefore, to transfer the large amount of data fast and effectively POF (Plastic Optical Fiber) can be used and the development of optic connector for connection between POFs is very important. In this study, for stable optical coupling of POF optic fiber Ferrule and Sleeve were designed and produced by considering the bond stability and the insertion loss according to the physical contact and roughness profile was evaluated. As a result of examining the insertion loss by physical contact method of two optic fibers, it showed the loss was about 1.895dB. According to the results from studying the condition of grinding section for POF mass production, the mass production condition was established as POF profile roughness of 6nm and the loss of 0.2dB or lower by controlling the film size and time step by step.

Many methods exist that promote wound healing, including light therapy, which consists of light beams that assist the human body in treating and sterilizing wounds, as well as regenerating cells. Irradiation with specific wavelengths of either laser or LED light has been shown to induce beneficial proliferation of fibroblasts that, depending on the size of the wound, can be effective in promoting wound healing. The experiments in this study utilized 8 week old 250~300 g Male Sprague Dawley Rats (ILAR Code: NTacSam:SD) and included a non-irradiation group and a 525 nm green LED irradiation group (n of each group

Fiber & Networking Co., LTD., Gwangju 500-706, Korea(Received July 22, 2010; Revised August 17, 2010; Accepted August 24, 2010)Abstract: In this research a ring light was developed so that a partial shadowless shooting for the patient's affected area at the medical treatment room and surgical operation room using high luminance light emitting diode (LED) for which attention is being paid as new lighting parts for medical purpose. LED which was applied to the development used high luminance three color LED for full color for which various color materialization and the adjustment of radiation intensity are possible and we can get white light in order to emphasize the delicate expression for generic tone of shooting object, strong highlight, simple shadow and three dimensional effect at the time of close-up shadowless shooting of the affected area. And at the time of design of ring light, the characteristics of LED and the loss of light at the time of penetrating light diffusion PC were considered so that intensity of illumination for over 150 lx can be obtained. The result of measurement of the intensity of illumination of the ring light that was developed revealed that maximum intensity of illumination of 225.7 lx was obtained, while smoke index was measured to be maximum 78 Ra in the case of Red(50%) Green(100%) and Blue LED(60%). We could confirm that response speed was also very fast as 1.72 ms.Keywords: Ring-light, Light emitting diode, Astral view

X-ray systems for medical treatment use noninvasive procedures. Being capable of locally inspecting the inside of the body, X-ray systems are routinely used for basic diagnosis. X-ray systems to be used for medical purposes were originally made with a gas filled tube inside an induction coil in the initial stages of development but with this approach it becomes difficult to take a satisfactory picture through thick body sections, non invasively. However continued development made it possible to take non-invasive pictures of breasts, blood vessels and other body parts through thick body sections. Recently, high-voltage X-ray generators of more compact size, increased generation efficiency, and sophisticated output control have become possible. All of these features are made possible by the use of a high-frequency output from an inverter and a fast switching semiconductor device. In this paper, we describe a new X-ray generator operating with a resonant inverter in order to reduce switching loss and high frequency noise. In addition, in order to identify the differences amongst types of rectification, we have compared output and the quality of X-ray pictures obtained with full-wave rectification and dual-voltage rectification methods.

X-ray system which is usefully used in diagnosis of the patient, being bombed of radioactivity is a big weak point when irradiates a X-ray to the human body so that ICRP restricted the radiation exposure tolerance of the human body. In order to reduce being bombed, the many research and development is now advanced. A lots of diagnostic X-ray machines have currently used due to the increase of occurrence efficiency of X-ray and precisely the output control by using the inverter which is a high speed switching semiconductors. For getting the confidence of the X-ray machine, the same radiation occurrence, same evaluation, and same irradiation condition are necessary when evaluates X-ray irradiation. It is the most important part for the accuracy of the test result and the patient safety. This research has produced the high voltage occurrence system of full-wave rectification method by using the LC resonance inverter, and evaluated the irradiation reproducibility in order to use it in diagnosis of the patient.

The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a InGaAlP laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. To raise the stimulus effect of the human body, the optical irradiation frequency could be set up. The study has executed in-vivo experiment by employing our own developed laser diode irradiation system to investigate the effects of the InGaAlP laser diode irradiation on the wound healing as a preliminary study aimed at the application of InGaAlP laser diode to wound healing of human skin injury. The study cut out whole skin layers of Sprague-Dawley rat on the back part in 1 cm circle and observed developing effects after executing light irradiation for 9 days, and in result it is found that the light irradiation rat showed earlier wound healing than non-irradiation rat during the experimental period. In addition, there are some differences found regarding the healing process between laser diode irradiated rats and non-irradiated ones.

Organic field-effect transistors (OFETs) are of interest for use in widely area electronic applications. We fabricated a copper phthalocyanine (CuPc) based field-effect transistor with different metal electrode. The CuPc FET device was made a top-contact type and the substrate temperature was room temperature. The source and drain electrodes were used an Au and Al materials. The CuPc thickness was 40 nm, and the channel length was , channel width was 3 mm. We observed a typical current-voltage (I-V) characteristics in CuPc FET with different electrode materials.

Low power laser therapy is internationally certified and is known to be effective in stimulating DNA in living organisms, increasing protein synthesis and activating cell division, smoothing blood circulation, promoting cell activation, cell regeneration and function. It also has anti-inflammatory, anti-edemic, anti-fibrous dysplastic and neuralogic hyperfunctional effects. This study was intended to verify the effect of LED irradiation therapy on wound healing in cell and animal tests by applying LED irradiator using a laser and laser diode, which was independently designed and developed to emit beams of similar wavelength to that of a laser. This equipment was fabricated using a micro-controller and a high brightness LED, and designed to enable us to control light irradiation time, intensity and reservation. In case of cell proliferation experiment, each experiment was performed to irradiation group and non-irradiation group for tissue cells. MTT assay method was chosen to verify the cell increase of two groups and the effect of irradiation on cell proliferation was examined by measuring 590 nm transmittance of micro-plate reader. In the wound healing experiment, 1 wounds on the skin wound of SD-Rat(Sprague-Dawley Rat) were made. Light irradiation group and none light irradiation group divided, each group was irradiated one hour a day for 9 days. As a result, the cell increase of tissue cells was verified in irradiation group as compared to non-irradiation group. And, compared with none light irradiation group, the lower incidence of inflammation and faster recovery was shown in light irradiation group.

Low level laser therapy has various therapy effects. This paper performed the basic study for fabricating the low level laser therapy apparatus, and one of the goals of this paper was to make this apparatus used handily. The apparatus has been fabricated using the laser diode and microprocessor unit. The apparatus used a 635 nm laser diode for laser medical therapy and was designed for a pulse width modulation type to increase stimulation effects. In this study, the designed device was used to find out how 635 nm laser diode affected the skin injury of SD-Rat(Sprague-Dawley Rat). We divided the participants into two groups; irradiation group which was irradiated 10 minutes a day for 9 consecutive days, and none irradiation group. The results showed that the study group had lower incidence of inflammation and faster recovery, compared with the control group.