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11 results on '"Mergel, Franziska"'

3. The SURVIVE study: Liquid biopsy guided surveillance after intermediate- to high-risk early breast cancer.

Author

Pfister, Kerstin, primary, Huesmann, Sophia, additional, Friedl, Thomas W. P., additional, Fink, Angelina, additional, Mehmeti, Forca, additional, Mergel, Franziska, additional, Schäffler, Henning, additional, Heublein, Sabine, additional, Hartkopf, Andreas Daniel, additional, Mueller, Volkmar, additional, Wiesmueller, Lisa Maria, additional, Fehm, Tanja N., additional, Pantel, Klaus, additional, Rack, Brigitte, additional, and Janni, Wolfgang, additional

Published
2024
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4. The Clinical Relevance of the NATALEE Study: Application of the NATALEE Criteria to a Real-World Cohort from Two Large German Breast Cancer Centers

Author

Schäffler, Henning, primary, Mergel, Franziska, additional, Pfister, Kerstin, additional, Lukac, Stephan, additional, Fink, Angelina, additional, Veselinovic, Kristina, additional, Rack, Brigitte, additional, Fink, Visnja, additional, Leinert, Elena, additional, Dimpfl, Moritz, additional, Englisch, Alexander, additional, Tegeler, Christian Martin, additional, Seller, Anna, additional, Grischke, Eva-Maria, additional, Hahn, Markus, additional, Volmer, Léa Louise, additional, Engler, Tobias, additional, Frevert, Marie Louise, additional, Taran, Florin Andrei, additional, Janni, Wolfgang, additional, Brucker, Sara Yvonne, additional, Hartkopf, Andreas Daniel, additional, and Dannehl, Dominik, additional

Published
2023
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7. Diagnosis, Therapy and Follow-up of Cervical Cancer Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) - Part 1 with Recommendations on Epidemiology, Screening, Diagnostics and Therapy

Author

Beckmann, Matthias W., Stuebs, Frederik A., Koch, Martin C., Mallmann, Peter, Dannecker, Christian, Dietl, Anna, Sevnina, Anna, Mergel, Franziska, Lotz, Laura, Hack, Carolin C., Ehret, Anne, Gantert, Daniel, Martignoni, Franca, Cieslik, Jan-Philipp, Menke, Jan, Ortmann, Olaf, Stromberger, Carmen, Oechsle, Karin, Hornemann, Beate, Mumm, Friederike, Grimm, Christoph, Sturdza, Alina, Wight, Edward, Loessl, Kristina, Golatta, Michael, Hagen, Volker, Dauelsberg, Timm, Diel, Ingo, Munstedt, Karsten, Merz, Eberhard, Vordermark, Dirk, Lindel, Katja, Wittekind, Christian, Kuppers, Volkmar, Lelle, Ralph, Neis, Klaus, Griesser, Henrik, Poschel, Birgit, Steiner, Manfred, Freitag, Ulrich, Gilster, Tobias, Schmittel, Alexander, Friedrich, Michael, Haase, Heidemarie, Gebhardt, Marion, Kiesel, Ludwig, Reinhardt, Michael, Kreissl, Michael, Kloke, Marianne, Horn, Lars-Christian, Wiedemann, Regina, Marnitz, Simone, Letsch, Anne, Zraik, Isabella, Mangold, Bernhard, Moeckel, Jochen, Alt, Celine, Wimberger, Pauline, Hillemanns, Peter, Paradies, Kerstin, Mustea, Alexander, Denschlag, Dominik, Henscher, Ulla, Tholen, Reina, Wesselmann, Simone, Fehm, Tanja, Beckmann, Matthias W., Stuebs, Frederik A., Koch, Martin C., Mallmann, Peter, Dannecker, Christian, Dietl, Anna, Sevnina, Anna, Mergel, Franziska, Lotz, Laura, Hack, Carolin C., Ehret, Anne, Gantert, Daniel, Martignoni, Franca, Cieslik, Jan-Philipp, Menke, Jan, Ortmann, Olaf, Stromberger, Carmen, Oechsle, Karin, Hornemann, Beate, Mumm, Friederike, Grimm, Christoph, Sturdza, Alina, Wight, Edward, Loessl, Kristina, Golatta, Michael, Hagen, Volker, Dauelsberg, Timm, Diel, Ingo, Munstedt, Karsten, Merz, Eberhard, Vordermark, Dirk, Lindel, Katja, Wittekind, Christian, Kuppers, Volkmar, Lelle, Ralph, Neis, Klaus, Griesser, Henrik, Poschel, Birgit, Steiner, Manfred, Freitag, Ulrich, Gilster, Tobias, Schmittel, Alexander, Friedrich, Michael, Haase, Heidemarie, Gebhardt, Marion, Kiesel, Ludwig, Reinhardt, Michael, Kreissl, Michael, Kloke, Marianne, Horn, Lars-Christian, Wiedemann, Regina, Marnitz, Simone, Letsch, Anne, Zraik, Isabella, Mangold, Bernhard, Moeckel, Jochen, Alt, Celine, Wimberger, Pauline, Hillemanns, Peter, Paradies, Kerstin, Mustea, Alexander, Denschlag, Dominik, Henscher, Ulla, Tholen, Reina, Wesselmann, Simone, and Fehm, Tanja

Abstract

Aim This update of the interdisciplinary S3 guideline on the Diagnosis, Therapy and Follow-up of Cervical Cancer (AWMF Registry No. 032/033OL) was published in March 2021. This updated guideline was funded by German Cancer Aid (Deutsche Krebshilfe) as part of the German Guideline Program in Oncology. The guideline was coordinated by the German Society of Gynecology and Obstetrics (Deutsche Gesellschaft fur Gynakologie und Geburtshilfe, DGGG) and the Working Group on Gynecological Oncology (Arbeitsgemeinschaft Gynakologische Onkologie, AGO) of the German Cancer Society (Deutsche Krebsgesellschaft, DKG). Method The process of updating the S3 guideline dating from 2014 was based on an appraisal of the available evidence using the criteria of evidence-based medicine, adaptations of existing evidence-based national and international guidelines or - if evidence was lacking - on a consensus of the specialists involved in compiling the update. After an initial review of the current literature was carried out according to a prescribed algorithm, several areas were identified which, in contrast to the predecessor version from September 2014, required new recommendations or statements which took account of more recently published literature and the appraisal of the new evidence. Recommendations The short version of this guideline consists of recommendations and statements on the epidemiology, screening, diagnostic workup and therapy of patients with cervical cancer. The most important new aspects included in this updated guideline include the newly published FIGO classification of 2018, the radical open surgery approach for cervical cancers up to FIGO stage IB1, and use of the sentinel lymph node technique for tumors = 2 cm. Other changes include the use of PET-CT, new options in radiotherapy (e.g., intensity-modulated radiotherapy, image-guided adaptive brachytherapy), and drug therapies to treat recurrence or metastasis.

Published
2022

8. Diagnosis, Therapy and Follow-up of Cervical Cancer Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) - Part 2 with Recommendations on Psycho-oncology, Rehabilitation, Follow-up, Recurrence, Palliative Therapy and Healthcare Facilities

Author

Fehm, Tanja, Stuebs, Frederik A., Koch, Martin C., Mallmann, Peter, Dannecker, Christian, Dietl, Anna, Sevnina, Anna, Mergel, Franziska, Lotz, Laura, Ehret, Anne, Gantert, Daniel, Martignoni, Franca, Cieslik, Jan-Philipp, Menke, Jan, Ortmann, Olaf, Stromberger, Carmen, Oechsle, Karin, Hornemann, Beate, Mumm, Friederike, Grimm, Christoph, Sturdza, Alina, Wight, Edward, Loessl, Kristina, Golatta, Michael, Hagen, Volker, Dauelsberg, Timm, Diel, Ingo, Muenstedt, Karsten, Merz, Eberhard, Vordermark, Dirk, Lindel, Katja, Wittekind, Christian, Kueppers, Volkmar, Lelle, Ralph, Neis, Klaus, Griesser, Henrik, Poeschel, Birgit, Steiner, Manfred, Freitag, Ulrich, Gilster, Tobias, Schmittel, Alexander, Friedrich, Michael, Haase, Heidemarie, Gebhardt, Marion, Kiesel, Ludwig, Reinhardt, Michael, Kreissl, Michael, Kloke, Marianne, Horn, Lars-Christian, Wiedemann, Regina, Marnitz, Simone, Letsch, Anne, Zraik, Isabella, Mangold, Bernhard, Moeckel, Jochen, Alt, Celine, Wimberger, Pauline, Hillemanns, Peter, Paradies, Kerstin, Mustea, Alexander, Denschlag, Dominik, Henscher, Ulla, Tholen, Reina, Wesselmann, Simone, Beckmann, Matthias W., Fehm, Tanja, Stuebs, Frederik A., Koch, Martin C., Mallmann, Peter, Dannecker, Christian, Dietl, Anna, Sevnina, Anna, Mergel, Franziska, Lotz, Laura, Ehret, Anne, Gantert, Daniel, Martignoni, Franca, Cieslik, Jan-Philipp, Menke, Jan, Ortmann, Olaf, Stromberger, Carmen, Oechsle, Karin, Hornemann, Beate, Mumm, Friederike, Grimm, Christoph, Sturdza, Alina, Wight, Edward, Loessl, Kristina, Golatta, Michael, Hagen, Volker, Dauelsberg, Timm, Diel, Ingo, Muenstedt, Karsten, Merz, Eberhard, Vordermark, Dirk, Lindel, Katja, Wittekind, Christian, Kueppers, Volkmar, Lelle, Ralph, Neis, Klaus, Griesser, Henrik, Poeschel, Birgit, Steiner, Manfred, Freitag, Ulrich, Gilster, Tobias, Schmittel, Alexander, Friedrich, Michael, Haase, Heidemarie, Gebhardt, Marion, Kiesel, Ludwig, Reinhardt, Michael, Kreissl, Michael, Kloke, Marianne, Horn, Lars-Christian, Wiedemann, Regina, Marnitz, Simone, Letsch, Anne, Zraik, Isabella, Mangold, Bernhard, Moeckel, Jochen, Alt, Celine, Wimberger, Pauline, Hillemanns, Peter, Paradies, Kerstin, Mustea, Alexander, Denschlag, Dominik, Henscher, Ulla, Tholen, Reina, Wesselmann, Simone, and Beckmann, Matthias W.

Abstract

Aim This is an update of the interdisciplinary S3-guideline on the Diagnosis, Therapy and Follow-up of Cervical Cancer (AWMF Registry No. 032/033OL), published in March 2021. The work on the updated guideline was funded by German Cancer Aid (Deutsche Krebshilfe) as part of the German Guideline Program in Oncology. The guideline was coordinated by the German Society of Gynecology and Obstetrics (Deutsche Gesellschaft fur Gynakologie und Geburtshilfe, DGGG) and the Working Group on Gynecological Oncology (Arbeitsgemeinschaft Gynakologische Onkologie, AGO) of the German Cancer Society (Deutsche Krebsgesellschaft, DKG). Method The process used to update the 2014 S3-guideline was based on an appraisal of the available evidence using the criteria of evidence- based medicine, adaptations of existing evidence-based national and international guidelines or - if evidence was lacking - on the consensus of the specialists involved in compiling the update. After an initial review of the current literature was carried out according to a prescribed algorithm, several areas were identified which, in contrast to the predecessor version from September 2014, required new recommendations or statements which would take account of more recently published literature and the recent appraisal of new evidence. Recommendations The short version of this guideline consists of recommendations and statements on palliative therapy and follow-up of patients with cervical cancer. The most important aspects included in this updated guideline are the new FIGO classification published in 2018, the radical open surgery approach used to treat cervical cancer up to FIGO stage IB1, and the use of the sentinel lymph node technique for tumors = 2 cm. Other changes include the use of PET-CT, new options in radiotherapy (e.g., intensity-modulated radiotherapy, image- guided adaptive brachytherapy), and drug therapies to treat recurrence or metastasis.

Published
2022

9. Diagnosis, Therapy and Follow-up of Cervical Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) – Part 1 with Recommendations on Epidemiology, Screening, Diagnostics and Therapy

Author

Beckmann, Matthias W., additional, Stübs, Frederik A., additional, Koch, Martin C., additional, Mallmann, Peter, additional, Dannecker, Christian, additional, Dietl, Anna, additional, Sevnina, Anna, additional, Mergel, Franziska, additional, Lotz, Laura, additional, Hack, Carolin C., additional, Ehret, Anne, additional, Gantert, Daniel, additional, Martignoni, Franca, additional, Cieslik, Jan-Philipp, additional, Menke, Jan, additional, Ortmann, Olaf, additional, Stromberger, Carmen, additional, Oechsle, Karin, additional, Hornemann, Beate, additional, Mumm, Friederike, additional, Grimm, Christoph, additional, Sturdza, Alina, additional, Wight, Edward, additional, Loessl, Kristina, additional, Golatta, Michael, additional, Hagen, Volker, additional, Dauelsberg, Timm, additional, Diel, Ingo, additional, Münstedt, Karsten, additional, Merz, Eberhard, additional, Vordermark, Dirk, additional, Lindel, Katja, additional, Wittekind, Christian, additional, Küppers, Volkmar, additional, Lellé, Ralph, additional, Neis, Klaus, additional, Griesser, Henrik, additional, Pöschel, Birgit, additional, Steiner, Manfred, additional, Freitag, Ulrich, additional, Gilster, Tobias, additional, Schmittel, Alexander, additional, Friedrich, Michael, additional, Haase, Heidemarie, additional, Gebhardt, Marion, additional, Kiesel, Ludwig, additional, Reinhardt, Michael, additional, Kreißl, Michael, additional, Kloke, Marianne, additional, Horn, Lars-Christian, additional, Wiedemann, Regina, additional, Marnitz, Simone, additional, Letsch, Anne, additional, Zraik, Isabella, additional, Mangold, Bernhard, additional, Möckel, Jochen, additional, Alt, Céline, additional, Wimberger, Pauline, additional, Hillemanns, Peter, additional, Paradies, Kerstin, additional, Mustea, Alexander, additional, Denschlag, Dominik, additional, Henscher, Ulla, additional, Tholen, Reina, additional, Wesselmann, Simone, additional, and Fehm, Tanja, additional

Published
2022
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10. [Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature].

Author

Mergel F, Schochter F, DeGregorio N, Janni W, Reister F, Friebe-Hofmann U, and Hüner B

Abstract

Adnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3 rd trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of hyperthyroidism and elevated ß-HCG. Hyperreactio luteinalis does not require therapy due to complete spontaneous remission postpartum, but is often treated surgically in graviditate. In our case we report a first-time gravida in the 31 st week of pregnancy with a symptomatic 25-cm multicystic, partly solid mass. After antenatal corticosteroid therapy, an exploratory laparotomy with right adnexectomy was performed on suspicion of malignancy. Histology revealed a hyperreactio luteinalis with an incidental finding of a serous borderline tumor of the ovary (FIGO IIIB). At 33 weeks of gestation, a pathological CTG was observed, and an urgent secondary caesarean section by re-longitudinal laparotomy was performed. Postpartum completion surgery revealed no further neoplastic cells., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)

Published
2023
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11. Diagnosis, Therapy and Follow-up of Cervical Cancer. Guideline of the DGGG, DKG and DKH (S3-Level, AWMF Registry No. 032/033OL, May 2021) - Part 2 with Recommendations on Psycho-oncology, Rehabilitation, Follow-up, Recurrence, Palliative Therapy and Healthcare Facilities.

Author

Fehm T, Stübs FA, Koch MC, Mallmann P, Dannecker C, Dietl A, Sevnina A, Mergel F, Lotz L, Ehret A, Gantert D, Martignoni F, Cieslik JP, Menke J, Ortmann O, Stromberger C, Oechsle K, Hornemann B, Mumm F, Grimm C, Sturdza A, Wight E, Loessl K, Golatta M, Hagen V, Dauelsberg T, Diel I, Münstedt K, Merz E, Vordermark D, Lindel K, Wittekind C, Küppers V, Lellé R, Neis K, Griesser H, Pöschel B, Steiner M, Freitag U, Gilster T, Schmittel A, Friedrich M, Haase H, Gebhardt M, Kiesel L, Reinhardt M, Kreißl M, Kloke M, Horn LC, Wiedemann R, Marnitz S, Letsch A, Zraik I, Mangold B, Möckel J, Alt C, Wimberger P, Hillemanns P, Paradies K, Mustea A, Denschlag D, Henscher U, Tholen R, Wesselmann S, and Beckmann MW

Abstract

Aim This is an update of the interdisciplinary S3-guideline on the Diagnosis, Therapy and Follow-up of Cervical Cancer (AWMF Registry No. 032/033OL), published in March 2021. The work on the updated guideline was funded by German Cancer Aid (Deutsche Krebshilfe) as part of the German Guideline Program in Oncology. The guideline was coordinated by the German Society of Gynecology and Obstetrics ( Deutsche Gesellschaft für Gynäkologie und Geburtshilfe , DGGG) and the Working Group on Gynecological Oncology ( Arbeitsgemeinschaft Gynäkologische Onkologie , AGO) of the German Cancer Society ( Deutsche Krebsgesellschaft , DKG). Method The process used to update the 2014 S3-guideline was based on an appraisal of the available evidence using the criteria of evidence-based medicine, adaptations of existing evidence-based national and international guidelines or - if evidence was lacking - on the consensus of the specialists involved in compiling the update. After an initial review of the current literature was carried out according to a prescribed algorithm, several areas were identified which, in contrast to the predecessor version from September 2014, required new recommendations or statements which would take account of more recently published literature and the recent appraisal of new evidence. Recommendations The short version of this guideline consists of recommendations and statements on palliative therapy and follow-up of patients with cervical cancer. The most important aspects included in this updated guideline are the new FIGO classification published in 2018, the radical open surgery approach used to treat cervical cancer up to FIGO stage IB1, and the use of the sentinel lymph node technique for tumors ≤ 2 cm. Other changes include the use of PET-CT, new options in radiotherapy (e.g., intensity-modulated radiotherapy, image-guided adaptive brachytherapy), and drug therapies to treat recurrence or metastasis., Competing Interests: Conflict of Interest/Interessenkonflikt The conflicts of interest of all the authors are listed in the long German-language version of the guideline report./Die Interessenkonflikte der Autoren sind im Leitlinienreport aufgelistet., (Thieme. All rights reserved.)

Published
2022
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