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[Hyperreactio Luteinalis and an Incidentally Detected FIGO IIIB Borderline Tumor of the Ovary in Pregnancy - Diagnostic, Therapy and Review of Literature].

Authors :
Mergel F
Schochter F
DeGregorio N
Janni W
Reister F
Friebe-Hofmann U
Hüner B
Source :
Zeitschrift fur Geburtshilfe und Neonatologie [Z Geburtshilfe Neonatol] 2023 Oct; Vol. 227 (5), pp. 390-397. Date of Electronic Publication: 2023 May 02.
Publication Year :
2023

Abstract

Adnexal masses affect 2-10% of all pregnancies. The highest incidence of 1-6% can be seen in the first trimester, with a high rate of spontaneous remission. Two percent of these masses are malignant neoplasms or borderline tumors. A rare benign mass of the adnexa in pregnancy is hyperreactio luteinalis characterised by bilateral, multicystic ovaries with a frequent occurrence in the 3 <superscript>rd</superscript> trimester. Clinical signs include maternal hyperandrogenaemia with virilisation, hyperemesis, nonspecific abdominal pain or laboratory findings of hyperthyroidism and elevated ß-HCG. Hyperreactio luteinalis does not require therapy due to complete spontaneous remission postpartum, but is often treated surgically in graviditate. In our case we report a first-time gravida in the 31 <superscript>st</superscript> week of pregnancy with a symptomatic 25-cm multicystic, partly solid mass. After antenatal corticosteroid therapy, an exploratory laparotomy with right adnexectomy was performed on suspicion of malignancy. Histology revealed a hyperreactio luteinalis with an incidental finding of a serous borderline tumor of the ovary (FIGO IIIB). At 33 weeks of gestation, a pathological CTG was observed, and an urgent secondary caesarean section by re-longitudinal laparotomy was performed. Postpartum completion surgery revealed no further neoplastic cells.<br />Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht.<br /> (Thieme. All rights reserved.)

Details

Language :
German
ISSN :
1439-1651
Volume :
227
Issue :
5
Database :
MEDLINE
Journal :
Zeitschrift fur Geburtshilfe und Neonatologie
Publication Type :
Academic Journal
Accession number :
37130551
Full Text :
https://doi.org/10.1055/a-2065-0231