1. ChemPhotoChem / The Right Light: De Novo Design of a Robust Modular Photochemical Reactor for Optimum Batch and Flow Chemistry
- Author
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Bonfield, Holly E., Bonfield, Holly E., Mercer, Kayleigh, Diaz‐Rodriguez, Alba, Cook, Gemma C., McKay, Blandine S. J., Slade, Pawel, Taylor, George M., Ooi, Wei Xiang, Williams, Jason D., Roberts, Jack P. M., Murphy, John A., Schmermund, Luca, Kroutil, Wolfgang, Mielke, Tamara, Cartwright, Jared, Grogan, Gideon, Edwards, Lee, Bonfield, Holly E., Bonfield, Holly E., Mercer, Kayleigh, Diaz‐Rodriguez, Alba, Cook, Gemma C., McKay, Blandine S. J., Slade, Pawel, Taylor, George M., Ooi, Wei Xiang, Williams, Jason D., Roberts, Jack P. M., Murphy, John A., Schmermund, Luca, Kroutil, Wolfgang, Mielke, Tamara, Cartwright, Jared, Grogan, Gideon, and Edwards, Lee
- Abstract
Having identified inconsistencies when repeating literatureexamples of photochemical transformations and difficultiesrecreating experimental setups, we devised several criteria thatan ideal lab-scale reactor should achieve. Herein, we introducea versatile photoreactor for high-throughput screening, prepa-rative-scale batch reactions and continuous processing, all witha single light source. The reactor utilizes interchangeable arraysof pseudo-monochromatic high-power LEDs in a range ofsynthetically useful wavelengths, combined with excellenttemperature control. Moreover, light intensity can be modu-lated in an accurate and straightforward manner. This systemhas subsequently been tested on a range of literature method-ologies., Europäische Kommission 764920, Engineering and Physical Sciences Research Council (EPSRC)(DE-588)5164381-9 EP/S035990/1, Accepted version
- Published
- 2020
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