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Mononuclear Fe(III) complexes containing an antipyrine Schiff base ligand were prepared and fully characterized, demonstrating a planar tetradentate coordination geometry. These complexes were found to be active for the hydrogen evolution reaction. Catalysis occurs at −1.4 V vs. Fc+/Fc, with an overpotential of 700 mV. The complexes are active electrocatalysts with a turnover frequency of 700 s−1. Furthermore, when paired with a chromophore and sacrificial donor, the complexes are active photocatalysts demonstrating >1700 turnovers during 40 hours of irradiation with a quantum yield of up to 5.4%. The catalysts have also been found to operate in natural water samples of varying salinity. [ABSTRACT FROM AUTHOR]

Introduction Nerves play an important role in cancer invasion. The innervation of prostate and gastric cancers promotes tumor growth and spread (1, 2), and perineural invasion is an aggressive form [...], Nerves enable cancer progression, as cancers have been shown to extend along nerves through the process of perineural invasion, which carries a poor prognosis. Furthermore, the innervation of some cancers promotes growth and metastases. It remains unclear, however, how nerves mechanistically contribute to cancer progression. Here, we demonstrated that Schwann cells promote cancer invasion through direct cancer cell contact. Histological evaluation of murine and human cancer specimens with perineural invasion uncovered a subpopulation of Schwann cells that associates with cancer cells. Coculture of cancer cells with dorsal root ganglion extracts revealed that Schwann cells direct cancer cells to migrate toward nerves and promote invasion in a contact-dependent manner. Upon contact, Schwann cells induced the formation of cancer cell protrusions in their direction and intercalated between the cancer cells, leading to cancer cell dispersion. The formation of these processes was dependent on Schwann cell expression of neural cell adhesion molecule 1 (NCAM1) and ultimately promoted perineural invasion. Moreover, NCAM1-deficient mice showed decreased neural invasion and less paralysis. Such Schwann cell behavior reflects normal Schwann cell programs that are typically activated in nerve repair but are instead exploited by cancer cells to promote perineural invasion and cancer progression.

Introduction: Rotator cuff tendons are typically reattached to the proximal humerus using transosseous sutures or suture anchors. Their primary mode of failure is at the tendon–bone interface. Methods: We investigated the addition of an adhesive, gelatin–resorcin–formalin (GRF) glue, to a single-row rotator cuff repair (RCR) on ex vivo sheep models. We hypothesised the addition of GRF glue would increase the repair construct strength. The study consisted of three groups of six sheep infraspinatus tendons with an inverted-mattress stitch, tension-band configuration. Group 1 was the control group where no glue was applied. Group 2 involved applying 2 × 2 cm of GRF glue to the infraspinatus footprint and a 2-min curing time. Group 3 allowed for a 15-min cure time. Results: Failure occurred at the tendon–bone–suture interface in 6/6 of the control group, and 4/6 from groups 2 and 3. Failure occurred via the suture pulling out of the anchor in 2/6 of groups 2 and 3. No significant differences were noted between all three groups in ultimate failure load, repair stiffness or total energy to failure (p > 0.05). Discussion: The addition of GRF glue to the tendon–bone–suture interface did not enhance RCR strength in an ovine model. [ABSTRACT FROM AUTHOR]

Research is done on low concentrations of short chain aliphatic alcohols and organic acids and bases, which suppress single-bubble sonoluminescence (SBSL) in water. In conclusion butyric acid and propylamine behave in the same manner, but only in their neutral forms, indicating that the SBSL suppression is due to processes occurring within the bubble.

The article discusses research into the emissions of sonoluminescence spectra when water is heated to differing temperatures.

An experiment indicates that the emission temperature inside imploding cavitation bubbles is reliant on the thermal conductivity and the polytropic ratio of the bubble contents. During bubble collapse the identity of the bubble contents mutates as a cavitation bubble works as a small chemical reactor.

Prayer is not an easy activity; it involves the destruction of the ego through the encounter with God. Prayer is either occupational, when God is found in the midst of daily activities, or spousal, when a deeper, more intimate communion is sought. Prayer cannot be taught, but an atmosphere of prayer can be cultivated. The way in which one monastic community creates an atmosphere of prayer is described.