328 results on '"McGeary, Ross P."'
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2. Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles
3. Structures of fungal and plant acetohydroxyacid synthases
4. Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse
5. Synthesis, evaluation and structural investigations of potent purple acid phosphatase inhibitors as drug leads for osteoporosis
6. Mapping of the Reaction Trajectory Catalyzed by Class I Ketol-Acid Reductoisomerase.
7. Revisiting Staudinger and Ruzicka's altered pyrethrolone: the cyclopentadienone dimers derived from pyrethrin I, cinerin I and jasmolin I.
8. Purple acid phosphatase inhibitors as leads for osteoporosis chemotherapeutics
9. Inhibitors for metallo-β-lactamases from the B1 and B3 subgroups provide an avenue to combat a major mechanism of antibiotic resistance
10. Structure-activity relationship study and optimisation of 2-aminopyrrole-1-benzyl-4,5-diphenyl-1H-pyrrole-3-carbonitrile as a broad spectrum metallo-β-lactamase inhibitor
11. Design, synthesis, and in vitro and biological evaluation of potent amino acid-derived thiol inhibitors of the metallo-β-lactamase IMP-1
12. Metal chelation, radical scavenging and inhibition of Aβ42 fibrillation by food constituents in relation to Alzheimer’s disease
13. Rivastigmine and metabolite analogues with putative Alzheimer’s disease-modifying properties in a Caenorhabditis elegans model
14. The applications of binuclear metallohydrolases in medicine: Recent advances in the design and development of novel drug leads for purple acid phosphatases, metallo-β-lactamases and arginases
15. Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals
16. Ligand modifications modulate the mechanism of binuclear phosphatase biomimetics
17. Synthesis and kinetic testing of new inhibitors for a metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
18. Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution – a potential target for anti-tuberculosis drug discovery
19. Rational Design of Potent Inhibitors of a Metallohydrolase Using a Fragment‐Based Approach
20. An ‘inside-out’ approach to suramin analogues
21. Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans
22. Cyclodextrin-Crosslinked Poly(Acrylic Acid): Adhesion and Controlled Release of Diflunisal and Fluconazole from Solid Dosage Forms
23. Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening
24. Vaccine delivery utilizing liposaccharides
25. Identification of novel target sites and an inhibitor of the dengue virus E protein
26. Cover Image
27. Discovery of drug‐like acetylcholinesterase inhibitors by rapid virtual screening of a 6.9 million compound database
28. Analogues of the Herbicide, N-Hydroxy-N-isopropyloxamate, Inhibit Mycobacterium tuberculosis Ketol-Acid Reductoisomerase and Their Prodrugs Are Promising Anti-TB Drug Leads
29. Discovery of a Pyrimidinedione Derivative with Potent Inhibitory Activity against Mycobacterium tuberculosis Ketol–Acid Reductoisomerase
30. Design, synthesis, biological evaluation and in silico studies of certain aryl sulfonyl hydrazones conjugated with 1,3-diaryl pyrazoles as potent metallo-β-lactamase inhibitors
31. Cyclodextrin-crosslinked poly(acrylic acid): Synthesis, physicochemical characterization and controlled release of diflunisal and fluconazole from hydrogels
32. Towards synthetic vaccines built on carbohydrate cores
33. Identification of Purple Acid Phosphatase Inhibitors by Fragment-Based Screening: Promising New Leads for Osteoporosis Therapeutics
34. Synthesis and Kinetic Testing of Tetrahydropyrimidine-2-thione and Pyrrole Derivatives as Inhibitors of the Metallo-β-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
35. The development and application of a novel safety-catch linker for BOC-based assembly of libraries of cyclic peptides
36. Conversion of glucosamine to galactosamine and allosamine derivatives: control of inversions of stereochemistry at C-3 and C-4
37. Inhibition studies of ketol-acid reductoisomerases from pathogenic microorganisms
38. Discovery, Synthesis and Evaluation of a Ketol‐Acid Reductoisomerase Inhibitor
39. Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops
40. A backbone linker for BOC-based peptide synthesis and on-resin cyclization: synthesis of stylostatin 1
41. Synthesis of cationic derivatives of Quil A and the preparation of cationic immune-stimulating complexes (ISCOMs)
42. Nine-membered Rings
43. Structural elements that modulate the substrate specificity of plant purple acid phosphatases: avenues for improved phosphorus acquisition in crops
44. Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse and widespread in the environment
45. The Binding Mode of an ADP Analogue to a Metallohydrolase Mimics the Likely Transition State
46. Synthesis and evaluation of novel purple acid phosphatase inhibitors
47. Carbohydrate-based templates for synthetic vaccines and drug delivery
48. Cyclic Polylactones and their Cyclic Polyorthoester Valence Tautomers: Potential Ionophores
49. Captopril analogues as metallo-β-lactamase inhibitors
50. The use of SWATH to analyse the dynamic changes of bacterial proteome of carbapanemase-producing Escherichia coli under antibiotic pressure
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