1. Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated Disease in a Liver Recipient and Literature Review
- Author
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Renata Scarpa Careta, Letícia Balarini Miranda, Júlia Vieira Moyzés, Anna Danielle Rodrigues Gandarella, Matheus Compart Hemerly, Aloísio Falqueto, Paulo Mendes Peçanha, Paula M Peçanha-Pietrobom, and Karoline Almeida Rangel
- Subjects
Male ,medicine.medical_specialty ,Antifungal Agents ,030231 tropical medicine ,Arthritis ,Paracoccidioides ,03 medical and health sciences ,0302 clinical medicine ,Amphotericin B ,Virology ,Trimethoprim, Sulfamethoxazole Drug Combination ,medicine ,Humans ,Disseminated disease ,Paracoccidioidomycosis ,business.industry ,Mortality rate ,Articles ,Middle Aged ,medicine.disease ,Dermatology ,Transplant Recipients ,Anti-Bacterial Agents ,Liver Transplantation ,Transplantation ,Skin Abscess ,Infectious Diseases ,Parasitology ,Solid organ transplantation ,business ,Brazil - Abstract
Paracoccidioidomycosis (PCM) is an endemic systemic mycosis that is of great importance in Latin America. Its occurrence in solid organ transplantation (SOT) is rare, but with high mortality rate. In this report, we describe a case of PCM in a liver transplant recipient 19 months after transplantation. The patient presented with multiple skin abscesses, arthritis, osteolytic lesions, and pulmonary and adrenal involvement. Despite the presence of disseminated disease and the patient’s immunosuppressed condition, the patient responded well to prolonged antifungal treatment with no sequelae, thus suggesting that early diagnosis and correct treatment may lead to favorable outcomes in SOT recipients with PCM.
- Published
- 2019
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