Back to Search
Start Over
Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated Disease in a Liver Recipient and Literature Review
- Source :
- Am J Trop Med Hyg
- Publication Year :
- 2019
- Publisher :
- American Society of Tropical Medicine and Hygiene, 2019.
-
Abstract
- Paracoccidioidomycosis (PCM) is an endemic systemic mycosis that is of great importance in Latin America. Its occurrence in solid organ transplantation (SOT) is rare, but with high mortality rate. In this report, we describe a case of PCM in a liver transplant recipient 19 months after transplantation. The patient presented with multiple skin abscesses, arthritis, osteolytic lesions, and pulmonary and adrenal involvement. Despite the presence of disseminated disease and the patient’s immunosuppressed condition, the patient responded well to prolonged antifungal treatment with no sequelae, thus suggesting that early diagnosis and correct treatment may lead to favorable outcomes in SOT recipients with PCM.
- Subjects :
- Male
medicine.medical_specialty
Antifungal Agents
030231 tropical medicine
Arthritis
Paracoccidioides
03 medical and health sciences
0302 clinical medicine
Amphotericin B
Virology
Trimethoprim, Sulfamethoxazole Drug Combination
medicine
Humans
Disseminated disease
Paracoccidioidomycosis
business.industry
Mortality rate
Articles
Middle Aged
medicine.disease
Dermatology
Transplant Recipients
Anti-Bacterial Agents
Liver Transplantation
Transplantation
Skin Abscess
Infectious Diseases
Parasitology
Solid organ transplantation
business
Brazil
Subjects
Details
- ISSN :
- 14761645 and 00029637
- Volume :
- 101
- Database :
- OpenAIRE
- Journal :
- The American Journal of Tropical Medicine and Hygiene
- Accession number :
- edsair.doi.dedup.....d9550404ca263c02aff9c0e2b32c0930