Back to Search Start Over

Case Report: Paracoccidioidomycosis in Solid Organ Transplantation: Disseminated Disease in a Liver Recipient and Literature Review

Authors :
Renata Scarpa Careta
Letícia Balarini Miranda
Júlia Vieira Moyzés
Anna Danielle Rodrigues Gandarella
Matheus Compart Hemerly
Aloísio Falqueto
Paulo Mendes Peçanha
Paula M Peçanha-Pietrobom
Karoline Almeida Rangel
Source :
Am J Trop Med Hyg
Publication Year :
2019
Publisher :
American Society of Tropical Medicine and Hygiene, 2019.

Abstract

Paracoccidioidomycosis (PCM) is an endemic systemic mycosis that is of great importance in Latin America. Its occurrence in solid organ transplantation (SOT) is rare, but with high mortality rate. In this report, we describe a case of PCM in a liver transplant recipient 19 months after transplantation. The patient presented with multiple skin abscesses, arthritis, osteolytic lesions, and pulmonary and adrenal involvement. Despite the presence of disseminated disease and the patient’s immunosuppressed condition, the patient responded well to prolonged antifungal treatment with no sequelae, thus suggesting that early diagnosis and correct treatment may lead to favorable outcomes in SOT recipients with PCM.

Details

ISSN :
14761645 and 00029637
Volume :
101
Database :
OpenAIRE
Journal :
The American Journal of Tropical Medicine and Hygiene
Accession number :
edsair.doi.dedup.....d9550404ca263c02aff9c0e2b32c0930